Cheap flights from Detroit to South America from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to South America departing on 2/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:15 am - 12:55 pm
DTW
-
MDE
8h 40m
1 stop
Spirit Airlines Logo
1:50 pm - 11:25 pm
MDE
-
DTW
8h 35m
1 stop
$211Spirit Airlines
Di, Mrz 10 - Mi, Mrz 11
Spirit Airlines Logo
5:09 am - 10:35 pm
DTW
-
LIM
17h 26m
2 stops
Spirit Airlines Logo
10:30 pm - 12:33 pm
LIM
-
DTW
13h 03m
2 stops
$218Spirit Airlines
Di, Mrz 3 - Di, Mrz 10
Spirit Airlines Logo
5:09 am - 9:35 pm
DTW
-
LIM
17h 26m
2 stops
Spirit Airlines Logo
10:30 pm - 12:33 pm
LIM
-
DTW
13h 03m
2 stops
$222Spirit Airlines
Mo, Mrz 9 - Di, Mrz 10
Spirit Airlines Logo
6:36 pm - 12:10 pm
DTW
-
CTG
17h 34m
1 stop
Spirit Airlines Logo
1:21 pm - 11:59 pm
CTG
-
DTW
9h 38m
1 stop
$229Spirit Airlines
Sa, Mrz 7 - Mi, Mrz 11
Spirit Airlines Logo
5:45 am - 2:13 pm
DTW
-
MDE
8h 28m
1 stop
Spirit Airlines Logo
2:15 pm - 9:15 am
MDE
-
DTW
18h 00m
1 stop
$231Spirit Airlines
Di, Mrz 3 - Di, Mrz 10
Spirit Airlines Logo
6:10 pm - 12:47 pm
DTW
-
BOG
18h 37m
1 stop
Spirit Airlines Logo
2:05 pm - 9:15 am
BOG
-
DTW
18h 10m
1 stop
$234Spirit Airlines
Di, Mrz 3 - Di, Mrz 10
Spirit Airlines Logo
5:09 am - 10:35 pm
DTW
-
LIM
17h 26m
2 stops
Spirit Airlines Logo
10:30 pm - 11:25 pm
LIM
-
DTW
23h 55m
2 stops
$237Spirit Airlines
Mo, Mrz 2 - Mo, Mrz 9
Multiple Airlines Logo
9:02 am - 1:10 pm
DTW
-
CTG
28h 08m
1 stop
Multiple Airlines Logo
2:21 pm - 1:30 pm
CTG
-
DTW
23h 09m
2 stops
$292Multiple Airlines
Do, Feb 19 - Fr, Feb 27
GOL Logo
5:57 pm - 12:35 pm
DTW
-
SDU
17h 38m
2 stops
GOL Logo
8:45 pm - 11:27 pm
SDU
-
DTW
27h 42m
2 stops
$876GOL
Mo, Mai 4 - Mi, Aug 19
GOL Logo
5:57 pm - 2:20 pm
DTW
-
SDU
19h 23m
2 stops
GOL Logo
6:00 am - 11:27 pm
SDU
-
DTW
18h 27m
2 stops
$933GOL
Mo, Mai 4 - Di, Aug 18

Spirit Airlines flights from Detroit to South America

Our best Spirit Airlines deals on Detroit to South America flight tickets
Spirit Airlines
Mar 10
DTW5:15 amDetroit Metropolitan Wayne County
8h 40m
1 stop
MDE12:55 pmMedellín Jose Maria Cordova Intl
Mar 11
MDE1:50 pmMedellín Jose Maria Cordova Intl
8h 35m
1 stop
DTW11:25 pmDetroit Metropolitan Wayne County
$211
Spirit Airlines
Mar 3
DTW5:09 amDetroit Metropolitan Wayne County
17h 26m
2 stops
LIM10:35 pmLima J Chavez Intl
Mar 10
LIM10:30 pmLima J Chavez Intl
13h 03m
2 stops
DTW12:33 pmDetroit Metropolitan Wayne County
$218
Spirit Airlines
Mar 9
DTW5:09 amDetroit Metropolitan Wayne County
17h 26m
2 stops
LIM9:35 pmLima J Chavez Intl
Mar 10
LIM10:30 pmLima J Chavez Intl
13h 03m
2 stops
DTW12:33 pmDetroit Metropolitan Wayne County
$222

GOL flights from Detroit to South America

Our best GOL deals on Detroit to South America flight tickets
GOL
Apr 13
DTW6:07 amDetroit Metropolitan Wayne County
36h 48m
2 stops
GRU7:55 pmSao Paulo Guarulhos Intl
May 7
GRU6:00 amSao Paulo Guarulhos Intl
18h 57m
2 stops
DTW11:57 pmDetroit Metropolitan Wayne County
$753
GOL
Feb 5
DTW12:15 pmDetroit Metropolitan Wayne County
17h 15m
2 stops
GRU7:30 amSao Paulo Guarulhos Intl
Feb 19
GRU6:00 amSao Paulo Guarulhos Intl
19h 39m
2 stops
DTW11:39 pmDetroit Metropolitan Wayne County
$1,142

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Februar 3, 2026.
Use the filters below to find and compare flights from Detroit to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Di 3/10

5:15 am-12:55 pm

1 stop8h 40m

Medellín Jose Maria Cordova Intl

Mi 3/11

1:50 pm-11:25 pm

1 stop8h 35m

$211

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Di 3/3

5:09 am-10:35 pm

2 stops17h 26m

Lima J Chavez Intl

Di 3/10

10:30 pm-12:33 pm

2 stops13h 03m

$218

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Mo 3/9

5:09 am-9:35 pm

2 stops17h 26m

Lima J Chavez Intl

Di 3/10

10:30 pm-12:33 pm

2 stops13h 03m

$222

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sa 3/7

6:36 pm-12:10 pm

1 stop17h 34m

Cartagena Rafael Nunez

Mi 3/11

1:21 pm-11:59 pm

1 stop9h 38m

$229

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Di 3/3

5:45 am-2:13 pm

1 stop8h 28m

Medellín Jose Maria Cordova Intl

Di 3/10

2:15 pm-9:15 am

1 stop18h 00m

$231

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Di 3/3

6:10 pm-12:47 pm

1 stop18h 37m

Bogotá El Dorado

Di 3/10

2:05 pm-9:15 am

1 stop18h 10m

$234

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Mo 3/2

5:09 am-10:35 pm

2 stops17h 26m

Lima J Chavez Intl

Mo 3/9

10:30 pm-11:25 pm

2 stops23h 55m

$237

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Do 2/19

9:02 am-1:10 pm

1 stop28h 08m

Cartagena Rafael Nunez

Fr 2/27

2:21 pm-1:30 pm

2 stops23h 09m

$292

DetroitRio de Janeiro

DTW - SDU

DTWSDU

Detroit Metropolitan Wayne County

Mo 5/4

5:57 pm-12:35 pm

2 stops17h 38m

Rio de Janeiro Santos Dumont

Mi 8/19

8:45 pm-11:27 pm

2 stops27h 42m

$876

DetroitRio de Janeiro

DTW - SDU

DTWSDU

Detroit Metropolitan Wayne County

Mo 5/4

5:57 pm-2:20 pm

2 stops19h 23m

Rio de Janeiro Santos Dumont

Di 8/18

6:00 am-11:27 pm

2 stops18h 27m

$933

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $524. If you aren’t able to travel during the month of September, then book flights to South America from Detroit during August instead. Flights to South America in August, while not as cheap as those in September, still average around $624.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $922 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $611 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 29% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time

7h 21m

Direct flights

None
The fastest flight from Detroit to South America takes 7h 21m
There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.
  • When did momondo last update prices for flights from Detroit to South America?

    Prices for flights from Detroit to South America refresh daily.

  • How many operators does momondo search for flights from Detroit to South America?

  • How old do you have to be to fly from Detroit to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $105Free CancellationRating
6.3
8,399 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $385Free CancellationRating
7.2
11,215 reviews
Search American Airlines flights
DeltaPriceFrom $527Free CancellationRating
7.9
8,137 reviews
Search Delta flights
Air CanadaPriceFrom $585Free CancellationRating
7.1
10,679 reviews
Search Air Canada flights
LATAM AirlinesPriceFrom $643Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $699Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $801Free CancellationRating
7.4
9,232 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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1 adult
Do 3/5
Do 3/12

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