Cheap flights from Detroit to South America from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to South America departing on 7/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:01 am - 10:11 pm
DTW
-
GYE
12h 10m
2 stops
American Airlines Logo
6:00 am - 9:10 am
GYE
-
DTW
26h 10m
2 stops
$387American Airlines
Wed, Sep 16 - Mon, Sep 21
JetBlue Logo
6:00 am - 11:30 am
DTW
-
CTG
6h 30m
1 stop
JetBlue Logo
12:35 pm - 9:45 pm
CTG
-
DTW
8h 10m
1 stop
$389JetBlue
Sat, Oct 17 - Sat, Oct 24
Multiple Airlines Logo
6:00 am - 3:22 pm
DTW
-
GYE
10h 22m
1 stop
Multiple Airlines Logo
4:19 pm - 9:23 am
GYE
-
DTW
16h 04m
1 stop
$451Multiple Airlines
Wed, Sep 16 - Mon, Sep 21
Multiple Airlines Logo
6:00 am - 3:20 pm
DTW
-
GYE
10h 20m
1 stop
Multiple Airlines Logo
5:31 pm - 9:56 pm
GYE
-
DTW
27h 25m
2 stops
$480Multiple Airlines
Thu, Aug 20 - Wed, Sep 23
GOL Logo
6:57 pm - 11:20 am
DTW
-
BOG
17h 23m
1 stop
GOL Logo
2:10 pm - 12:28 pm
BOG
-
DTW
21h 18m
2 stops
$574GOL
Wed, Jun 24 - Mon, Aug 24
LATAM Airlines Logo
7:20 am - 7:15 pm
DTW
-
BOG
12h 55m
1 stop
LATAM Airlines Logo
8:40 am - 10:10 pm
BOG
-
DTW
12h 30m
1 stop
$583LATAM Airlines
Tue, Aug 11 - Tue, Aug 25
Air Canada Logo
3:55 pm - 3:15 am
DTW
-
LIM
11h 20m
1 stop
Air Canada Logo
8:00 am - 5:40 pm
LIM
-
DTW
33h 40m
2 stops
$594Air Canada
Fri, Nov 20 - Sat, Nov 28
Air Canada Logo
3:55 pm - 6:10 am
DTW
-
LIM
38h 15m
2 stops
Air Canada Logo
8:00 am - 5:40 pm
LIM
-
DTW
33h 40m
2 stops
$602Air Canada
Fri, Nov 20 - Sat, Nov 28
GOL Logo
6:00 am - 10:45 am
DTW
-
GIG
26h 45m
2 stops
GOL Logo
10:30 pm - 11:49 pm
GIG
-
DTW
27h 19m
2 stops
$839GOL
Thu, Nov 5 - Tue, Nov 10
LATAM Airlines Logo
2:24 pm - 1:35 pm
DTW
-
CUZ
24h 11m
2 stops
LATAM Airlines Logo
3:30 pm - 3:04 pm
CUZ
-
DTW
22h 34m
2 stops
$1,089LATAM Airlines
Tue, Sep 1 - Tue, Sep 22

LATAM Airlines flights from Detroit to South America

Our best LATAM Airlines deals on Detroit to South America flight tickets
LATAM Airlines
Sep 9
DTW8:45 pmDetroit Metropolitan Wayne County
17h 30m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Sep 16
CTG9:30 pmCartagena Rafael Nunez
23h 26m
2 stops
DTW9:56 pmDetroit Metropolitan Wayne County
$533
LATAM Airlines
Sep 16
DTW7:20 pmDetroit Metropolitan Wayne County
18h 55m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Sep 23
CTG5:30 amCartagena Rafael Nunez
15h 26m
2 stops
DTW9:56 pmDetroit Metropolitan Wayne County
$561
LATAM Airlines
Aug 11
DTW7:20 amDetroit Metropolitan Wayne County
12h 55m
1 stop
BOG7:15 pmBogotá El Dorado
Aug 25
BOG8:40 amBogotá El Dorado
12h 30m
1 stop
DTW10:10 pmDetroit Metropolitan Wayne County
$583

GOL flights from Detroit to South America

Our best GOL deals on Detroit to South America flight tickets
GOL
Sep 9
DTW7:37 pmDetroit Metropolitan Wayne County
27h 34m
2 stops
GYE10:11 pmGuayaquil Jose Joaquin de Olmedo
Sep 14
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
15h 57m
1 stop
DTW10:57 pmDetroit Metropolitan Wayne County
$570
GOL
Jun 24
DTW6:57 pmDetroit Metropolitan Wayne County
17h 23m
1 stop
BOG11:20 amBogotá El Dorado
Aug 24
BOG2:10 pmBogotá El Dorado
21h 18m
2 stops
DTW12:28 pmDetroit Metropolitan Wayne County
$574
GOL
Jul 23
DTW6:10 amDetroit Metropolitan Wayne County
16h 07m
2 stops
BOG9:17 pmBogotá El Dorado
Jul 29
BOG6:30 amBogotá El Dorado
15h 27m
1 stop
DTW10:57 pmDetroit Metropolitan Wayne County
$584

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 1, 2026.
Use the filters below to find and compare flights from Detroit to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Wed 9/16

11:01 am-10:11 pm

2 stops12h 10m

Guayaquil Jose Joaquin de Olmedo

Mon 9/21

6:00 am-9:10 am

2 stops26h 10m

$387
Quickest round-trip

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 10/17

6:00 am-11:30 am

1 stop6h 30m

Cartagena Rafael Nunez

Sat 10/24

12:35 pm-9:45 pm

1 stop8h 10m

$389

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Wed 9/16

6:00 am-3:22 pm

1 stop10h 22m

Guayaquil Jose Joaquin de Olmedo

Mon 9/21

4:19 pm-9:23 am

1 stop16h 04m

$451

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Thu 8/20

6:00 am-3:20 pm

1 stop10h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 9/23

5:31 pm-9:56 pm

2 stops27h 25m

$480

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Wed 6/24

6:57 pm-11:20 am

1 stop17h 23m

Bogotá El Dorado

Mon 8/24

2:10 pm-12:28 pm

2 stops21h 18m

$574

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Tue 8/11

7:20 am-7:15 pm

1 stop12h 55m

Bogotá El Dorado

Tue 8/25

8:40 am-10:10 pm

1 stop12h 30m

$583

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Fri 11/20

3:55 pm-3:15 am

1 stop11h 20m

Lima J Chavez Intl

Sat 11/28

8:00 am-5:40 pm

2 stops33h 40m

$594

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Fri 11/20

3:55 pm-6:10 am

2 stops38h 15m

Lima J Chavez Intl

Sat 11/28

8:00 am-5:40 pm

2 stops33h 40m

$602

DetroitRio de Janeiro

DTW - GIG

DTWGIG

Detroit Metropolitan Wayne County

Thu 11/5

6:00 am-10:45 am

2 stops26h 45m

Rio de Janeiro–Galeão Intl

Tue 11/10

10:30 pm-11:49 pm

2 stops27h 19m

$839

DetroitCusco

DTW - CUZ

DTWCUZ

Detroit Metropolitan Wayne County

Tue 9/1

2:24 pm-1:35 pm

2 stops24h 11m

Cusco Velazco Astete

Tue 9/22

3:30 pm-3:04 pm

2 stops22h 34m

$1,089

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $105. If you aren’t able to travel during the month of October, then book flights to South America from Detroit during November instead. Flights to South America in November, while not as cheap as those in October, still average around $159.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $813 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $437 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 33% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from Detroit to South America takes 6h 30m
There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Frequently asked questions about flying from Detroit to South America

  • When did momondo last update prices for flights from Detroit to South America?

    Prices for flights from Detroit to South America refresh daily.

  • How many operators does momondo search for flights from Detroit to South America?

  • How old do you have to be to fly from Detroit to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $274Free CancellationRating
7.9
8,398 reviews
Search Delta flights
American AirlinesPriceFrom $452Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
JetBluePriceFrom $467Free CancellationRating
7.1
2,981 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $650Free CancellationRating
7.5
1,569 reviews
Search Copa Airlines flights
Air CanadaPriceFrom $766Free CancellationRating
7.1
11,114 reviews
Search Air Canada flights
LATAM AirlinesPriceFrom $787Free CancellationRating
7.4
1,920 reviews
Search LATAM Airlines flights
United AirlinesPriceFrom $1,119Free CancellationRating
7.4
9,778 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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1 adult
Wed 7/1
Wed 7/8

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