What is the cheapest airline that flies from Detroit to South America?

Spirit Airlines, Delta, and United Airlines are the most popular carriers operating from Detroit to South America

What airlines fly to South America?

Spirit Airlines, Delta and American Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Spirit Airlines is the first choice among our users, with 30% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of November 2025, there are 7 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$148 Cheap Flights from Detroit to South America in 2025/26

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Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 1:15 pmDTW-CTG

7h 15m1 stop

2:21 pm - 10:44 pmCTG-DTW

8h 23m1 stop

$291Spirit Airlines

Find Deal

Tue, Jan 20 - Tue, Jan 27

7:42 pm - 10:55 amDTW-MDE

15h 13m1 stop

2:05 am - 10:08 amMDE-DTW

8h 03m1 stop

$295Spirit Airlines

Find Deal

Wed, Dec 10 - Thu, Dec 11

6:00 am - 1:10 pmDTW-CTG

7h 10m1 stop

2:15 pm - 12:19 amCTG-DTW

10h 04m1 stop

$304Spirit Airlines

Find Deal

Mon, Dec 8 - Fri, Dec 12

6:00 am - 1:10 pmDTW-CTG

7h 10m1 stop

2:15 pm - 12:19 amCTG-DTW

10h 04m1 stop

$315Spirit Airlines

Find Deal

Mon, Dec 8 - Fri, Dec 12

6:36 pm - 1:15 pmDTW-CTG

18h 39m1 stop

2:21 pm - 10:44 pmCTG-DTW

8h 23m1 stop

$318Spirit Airlines

Find Deal

Thu, Jan 29 - Thu, Feb 5

10:54 am - 1:15 pmDTW-CTG

26h 21m1 stop

2:21 pm - 9:46 amCTG-DTW

19h 25m2 stops

$320Multiple Airlines

Find Deal

Thu, Jan 29 - Thu, Feb 5

2:28 pm - 1:09 amDTW-MDE

10h 41m1 stop

2:05 am - 3:40 pmMDE-DTW

37h 35m2 stops

$341Multiple Airlines

Find Deal

Thu, Dec 4 - Sun, Dec 7

5:56 pm - 12:50 pmDTW-GIG

17h 54m2 stops

6:05 am - 10:45 pmGIG-DTW

17h 40m2 stops

$707GOL

Find Deal

Fri, May 8 - Fri, May 15

6:15 pm - 12:05 pmDTW-GIG

15h 50m1 stop

9:00 pm - 5:35 pmGIG-DTW

22h 35m1 stop

$769Air Canada

Find Deal

Tue, Jan 27 - Wed, Feb 4

5:56 pm - 4:50 pmDTW-GIG

21h 54m2 stops

5:55 pm - 10:45 pmGIG-DTW

29h 50m2 stops

$770GOL

Find Deal

Sat, May 9 - Sat, May 16

Delta flights from Detroit to South America

Our best Delta deals on Detroit to South America flight tickets

Delta

May 4

DTW9:25 amDetroit Metropolitan Wayne County

11h 44m

1 stop

UIO8:09 pmQuito Mariscal Sucr

May 14

UIO11:20 pmQuito Mariscal Sucr

9h 04m

1 stop

DTW9:24 amDetroit Metropolitan Wayne County

$685

Find similar

Delta

May 4

DTW9:25 amDetroit Metropolitan Wayne County

10h 40m

2 stops

UIO7:05 pmQuito Mariscal Sucr

May 14

UIO9:11 amQuito Mariscal Sucr

14h 34m

2 stops

DTW12:45 amDetroit Metropolitan Wayne County

$689

Find similar

Delta

Jan 14

DTW2:10 pmDetroit Metropolitan Wayne County

15h 07m

2 stops

UIO5:17 amQuito Mariscal Sucr

Jan 21

UIO7:00 pmQuito Mariscal Sucr

16h 01m

2 stops

DTW11:01 amDetroit Metropolitan Wayne County

$729

Find similar

American Airlines flights from Detroit to South America

Our best American Airlines deals on Detroit to South America flight tickets

American Airlines

May 1

DTW6:17 amDetroit Metropolitan Wayne County

15h 28m

1 stop

UIO8:45 pmQuito Mariscal Sucr

May 10

UIO6:50 amQuito Mariscal Sucr

9h 29m

1 stop

DTW5:19 pmDetroit Metropolitan Wayne County

$705

Find similar

American Airlines

May 1

DTW6:17 amDetroit Metropolitan Wayne County

15h 28m

1 stop

UIO8:45 pmQuito Mariscal Sucr

May 10

UIO11:40 pmQuito Mariscal Sucr

14h 03m

2 stops

DTW2:43 pmDetroit Metropolitan Wayne County

$709

Find similar

American Airlines

Jan 14

DTW12:15 pmDetroit Metropolitan Wayne County

11h 32m

1 stop

UIO11:47 pmQuito Mariscal Sucr

Jan 20

UIO12:49 amQuito Mariscal Sucr

10h 41m

1 stop

DTW11:30 amDetroit Metropolitan Wayne County

$725

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Tue 1/20

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Tue 1/27

2:21 pm-10:44 pm

1 stop8h 23m

$291

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Wed 12/10

7:42 pm-10:55 am

1 stop15h 13m

Medellín Jose Maria Cordova Intl

Thu 12/11

2:05 am-10:08 am

1 stop8h 03m

$295

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Mon 12/8

6:00 am-1:10 pm

1 stop7h 10m

Cartagena Rafael Nunez

Fri 12/12

2:15 pm-12:19 am

1 stop10h 04m

$304

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Mon 12/8

6:00 am-1:10 pm

1 stop7h 10m

Cartagena Rafael Nunez

Fri 12/12

2:15 pm-12:19 am

1 stop10h 04m

$315

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Thu 1/29

6:36 pm-1:15 pm

1 stop18h 39m

Cartagena Rafael Nunez

Thu 2/5

2:21 pm-10:44 pm

1 stop8h 23m

$318

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Thu 1/29

10:54 am-1:15 pm

1 stop26h 21m

Cartagena Rafael Nunez

Thu 2/5

2:21 pm-9:46 am

2 stops19h 25m

$320

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 12/4

2:28 pm-1:09 am

1 stop10h 41m

Medellín Jose Maria Cordova Intl

Sun 12/7

2:05 am-3:40 pm

2 stops37h 35m

$341

DetroitRio de Janeiro

DTW - GIG

DTWGIG

Detroit Metropolitan Wayne County

Fri 5/8

5:56 pm-12:50 pm

2 stops17h 54m

Rio de Janeiro–Galeão Intl

Fri 5/15

6:05 am-10:45 pm

2 stops17h 40m

$707

DetroitRio de Janeiro

DTW - GIG

DTWGIG

Detroit Metropolitan Wayne County

Tue 1/27

6:15 pm-12:05 pm

1 stop15h 50m

Rio de Janeiro–Galeão Intl

Wed 2/4

9:00 pm-5:35 pm

1 stop22h 35m

$769

DetroitRio de Janeiro

DTW - GIG

DTWGIG

Detroit Metropolitan Wayne County

Sat 5/9

5:56 pm-4:50 pm

2 stops21h 54m

Rio de Janeiro–Galeão Intl

Sat 5/16

5:55 pm-10:45 pm

2 stops29h 50m

$770

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $524. If you aren’t able to travel during the month of September, then book flights to South America from Detroit during August instead. Flights to South America in August, while not as cheap as those in September, still average around $622.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Detroit to South America is on a Tuesday when prices can be found for as low as $793. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Detroit to South America for around $999.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Detroit to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $923. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $954 on average. Flights to South America from Detroit in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $979 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $658 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Direct flights	None

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of November 2025, there are 7 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $104	Free Cancellation	Rating 6.3 8,158 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $417	Free Cancellation	Rating 7.2 11,047 reviews	Search American Airlines flights
Delta	PriceFrom $527	Free Cancellation	Rating 7.9 8,002 reviews	Search Delta flights
United Airlines	PriceFrom $550	Free Cancellation	Rating 7.4 9,029 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $583	Free Cancellation	Rating 7.6 1,566 reviews	Search Copa Airlines flights
Air Canada	PriceFrom $585	Free Cancellation	Rating 7.1 10,463 reviews	Search Air Canada flights
LATAM Airlines	PriceFrom $652	Free Cancellation	Rating 7.5 1,882 reviews	Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.