Cheap flights from Detroit to South America from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to South America departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:50 pm - 1:22 pm
DTW
-
MDE
19h 32m
1 stop
Multiple Airlines Logo
2:06 pm - 12:46 am
MDE
-
DTW
9h 40m
1 stop
$326Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
3:57 pm - 1:12 pm
DTW
-
BOG
22h 15m
1 stop
Multiple Airlines Logo
2:07 pm - 9:10 am
BOG
-
DTW
42h 03m
2 stops
$358Multiple Airlines
Fri, Apr 17 - Sat, May 2
Spirit Airlines Logo
8:15 am - 12:21 am
DTW
-
MDE
17h 06m
1 stop
Spirit Airlines Logo
2:06 pm - 5:18 pm
MDE
-
DTW
26h 12m
2 stops
$358Spirit Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
8:49 pm - 12:06 pm
DTW
-
CTG
40h 17m
2 stops
Multiple Airlines Logo
1:11 pm - 11:59 pm
CTG
-
DTW
9h 48m
1 stop
$359Multiple Airlines
Fri, Apr 24 - Fri, May 1
Spirit Airlines Logo
5:45 am - 1:11 pm
DTW
-
BOG
8h 26m
1 stop
Spirit Airlines Logo
2:10 pm - 11:59 pm
BOG
-
DTW
8h 49m
1 stop
$363Spirit Airlines
Sun, Apr 12 - Tue, Apr 14
Air Canada Logo
10:45 am - 9:00 am
DTW
-
GRU
21h 15m
1 stop
Air Canada Logo
9:00 pm - 9:25 pm
GRU
-
DTW
25h 25m
1 stop
$795Air Canada
Mon, May 25 - Mon, Jun 8
Air Canada Logo
10:15 am - 2:30 pm
DTW
-
EZE
27h 15m
2 stops
Air Canada Logo
4:35 pm - 9:29 pm
EZE
-
DTW
29h 54m
2 stops
$951Air Canada
Tue, Sep 1 - Wed, Sep 23
Azul Logo
10:15 am - 2:30 pm
DTW
-
EZE
27h 15m
2 stops
Azul Logo
4:35 pm - 10:07 am
EZE
-
DTW
18h 32m
1 stop
$981Azul
Tue, Sep 1 - Wed, Sep 23
Azul Logo
10:15 am - 2:30 pm
DTW
-
EZE
27h 15m
2 stops
Azul Logo
4:35 pm - 9:25 pm
EZE
-
DTW
53h 50m
2 stops
$984Azul
Wed, May 20 - Wed, Jun 3
GOL Logo
6:19 am - 4:40 pm
DTW
-
SDU
33h 21m
2 stops
GOL Logo
6:00 am - 10:52 pm
SDU
-
DTW
17h 52m
2 stops
$1,016GOL
Thu, Sep 3 - Sun, Sep 27

Spirit Airlines flights from Detroit to South America

Our best Spirit Airlines deals on Detroit to South America flight tickets
Spirit Airlines
Apr 9
DTW6:50 pmDetroit Metropolitan Wayne County
19h 21m
1 stop
BOG1:11 pmBogotá El Dorado
Apr 14
BOG2:10 pmBogotá El Dorado
8h 49m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$334
Spirit Airlines
Apr 9
DTW4:17 pmDetroit Metropolitan Wayne County
9h 04m
1 stop
MDE12:21 amMedellín Jose Maria Cordova Intl
Apr 13
MDE1:17 amMedellín Jose Maria Cordova Intl
12h 55m
1 stop
DTW3:12 pmDetroit Metropolitan Wayne County
$344
Spirit Airlines
Apr 10
DTW6:50 pmDetroit Metropolitan Wayne County
18h 16m
1 stop
CTG12:06 pmCartagena Rafael Nunez
Apr 14
CTG1:14 pmCartagena Rafael Nunez
8h 18m
1 stop
DTW10:32 pmDetroit Metropolitan Wayne County
$348

United Airlines flights from Detroit to South America

Our best United Airlines deals on Detroit to South America flight tickets
United Airlines
Sep 1
DTW11:00 amDetroit Metropolitan Wayne County
13h 25m
2 stops
UIO11:25 pmQuito Mariscal Sucr
Sep 8
UIO7:25 amQuito Mariscal Sucr
13h 59m
1 stop
DTW10:24 pmDetroit Metropolitan Wayne County
$757
United Airlines
Jul 12
DTW6:15 amDetroit Metropolitan Wayne County
18h 10m
1 stop
UIO11:25 pmQuito Mariscal Sucr
Jul 18
UIO12:35 amQuito Mariscal Sucr
22h 23m
2 stops
DTW11:58 pmDetroit Metropolitan Wayne County
$855
United Airlines
Apr 13
DTW9:00 amDetroit Metropolitan Wayne County
15h 00m
1 stop
LIM11:00 pmLima J Chavez Intl
Apr 17
LIM11:05 pmLima J Chavez Intl
17h 26m
2 stops
DTW5:31 pmDetroit Metropolitan Wayne County
$1,012

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Detroit to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Mon 4/13

6:50 pm-1:22 pm

1 stop19h 32m

Medellín Jose Maria Cordova Intl

Fri 4/17

2:06 pm-12:46 am

1 stop9h 40m

$326

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Fri 4/17

3:57 pm-1:12 pm

1 stop22h 15m

Bogotá El Dorado

Sat 5/2

2:07 pm-9:10 am

2 stops42h 03m

$358

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Mon 4/13

8:15 am-12:21 am

1 stop17h 06m

Medellín Jose Maria Cordova Intl

Fri 4/17

2:06 pm-5:18 pm

2 stops26h 12m

$358

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Fri 4/24

8:49 pm-12:06 pm

2 stops40h 17m

Cartagena Rafael Nunez

Fri 5/1

1:11 pm-11:59 pm

1 stop9h 48m

$359
Quickest round-trip

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Sun 4/12

5:45 am-1:11 pm

1 stop8h 26m

Bogotá El Dorado

Tue 4/14

2:10 pm-11:59 pm

1 stop8h 49m

$363

DetroitSao Paulo

DTW - GRU

DTWGRU

Detroit Metropolitan Wayne County

Mon 5/25

10:45 am-9:00 am

1 stop21h 15m

Sao Paulo Guarulhos Intl

Mon 6/8

9:00 pm-9:25 pm

1 stop25h 25m

$795

DetroitBuenos Aires

DTW - EZE

DTWEZE

Detroit Metropolitan Wayne County

Tue 9/1

10:15 am-2:30 pm

2 stops27h 15m

Buenos Aires Ministro Pistarini

Wed 9/23

4:35 pm-9:29 pm

2 stops29h 54m

$951

DetroitBuenos Aires

DTW - EZE

DTWEZE

Detroit Metropolitan Wayne County

Tue 9/1

10:15 am-2:30 pm

2 stops27h 15m

Buenos Aires Ministro Pistarini

Wed 9/23

4:35 pm-10:07 am

1 stop18h 32m

$981

DetroitBuenos Aires

DTW - EZE

DTWEZE

Detroit Metropolitan Wayne County

Wed 5/20

10:15 am-2:30 pm

2 stops27h 15m

Buenos Aires Ministro Pistarini

Wed 6/3

4:35 pm-9:25 pm

2 stops53h 50m

$984

DetroitRio de Janeiro

DTW - SDU

DTWSDU

Detroit Metropolitan Wayne County

Thu 9/3

6:19 am-4:40 pm

2 stops33h 21m

Rio de Janeiro Santos Dumont

Sun 9/27

6:00 am-10:52 pm

2 stops17h 52m

$1,016

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, March is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $436. If you aren’t able to travel during the month of March, then book flights to South America from Detroit during September instead. Flights to South America in September, while not as cheap as those in March, still average around $524.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $847 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $555 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 27% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time

7h 26m

Direct flights

None
The fastest flight from Detroit to South America takes 7h 26m
There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Frequently asked questions about flying from Detroit to South America

  • When did momondo last update prices for flights from Detroit to South America?

    Prices for flights from Detroit to South America refresh daily.

  • How many operators does momondo search for flights from Detroit to South America?

  • How old do you have to be to fly from Detroit to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $266Free CancellationRating
6.3
8,578 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $417Free CancellationRating
7.1
11,549 reviews
Search American Airlines flights
DeltaPriceFrom $563Free CancellationRating
7.9
8,374 reviews
Search Delta flights
LATAM AirlinesPriceFrom $643Free CancellationRating
7.4
1,908 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $650Free CancellationRating
7.5
1,578 reviews
Search Copa Airlines flights
Air CanadaPriceFrom $773Free CancellationRating
7.1
10,886 reviews
Search Air Canada flights
United AirlinesPriceFrom $1,078Free CancellationRating
7.4
9,539 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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1 adult
Sat 5/2
Sat 5/9

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