What is the cheapest airline that flies from Detroit to South America?

American Airlines, United Airlines, and Copa Airlines are the most popular carriers operating from Detroit to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of September 2026, there are 8 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$192 Cheap Flights from Detroit to South America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:10 pm - 3:36 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

18h 26m2 stops Chicago O'Hare Intl Miami

4:37 pm - 10:30 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

17h 53m2 stops Miami Charlotte Douglas

$430American Airlines

Mon, Nov 9 - Tue, Nov 17

6:00 am - 3:36 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

9h 36m1 stop Miami

2:35 pm - 10:55 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 20m1 stop Miami

$430American Airlines

Mon, Nov 9 - Tue, Nov 17

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:37 pm - 9:41 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 04m1 stop Fort Lauderdale

$437JetBlue

Tue, Oct 20 - Thu, Oct 22

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:44 pm - 9:42 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

7h 58m1 stop Fort Lauderdale

$437JetBlue

Tue, Oct 20 - Wed, Oct 28

6:00 am - 12:34 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 34m1 stop Fort Lauderdale

3:30 pm - 9:28 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

17h 58m1 stop Atlanta Hartsfield-Jackson

$507Multiple Airlines

Tue, Mar 2 - Tue, Mar 9

12:31 pm - 10:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

33h 39m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:40 am - 10:37 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 57m1 stop Houston George Bush Intcntl

$527United Airlines

Thu, Jan 28 - Thu, Feb 4

7:26 am - 10:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

38h 44m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:40 am - 10:56 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

12h 16m1 stop Houston George Bush Intcntl

$527United Airlines

Sun, Nov 1 - Sun, Nov 8

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

4:30 am - 10:02 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

16h 32m2 stops Bogotá El Dorado Miami

$529Multiple Airlines

Tue, Oct 20 - Thu, Oct 22

8:25 am - 7:30 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

11h 05m1 stop Atlanta Hartsfield-Jackson

6:35 pm - 11:25 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

16h 50m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$775Delta

Mon, Nov 23 - Tue, Dec 8

8:25 am - 8:10 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

11h 45m2 stops Atlanta Hartsfield-Jackson Miami

3:55 pm - 9:34 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

17h 39m1 stop Atlanta Hartsfield-Jackson

$780Delta

Thu, Nov 26 - Thu, Dec 3

Cheap last minute flights

Enter your travel dates to find the best prices.

7:55 pm - 1:55 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

19h 00m1 stop Boston Logan Intl

11:05 pm - 6:08 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

19h 03m1 stop New York John F Kennedy Intl

$694Multiple Airlines

Fri, Sep 25 - Mon, Nov 9

7:55 pm - 1:55 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

19h 00m1 stop Boston Logan Intl

5:50 pm - 6:08 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

24h 18m2 stops Medellín Jose Maria Cordova Intl New York John F Kennedy Intl

$716Multiple Airlines

Fri, Sep 25 - Mon, Nov 9

7:00 am - 12:52 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 52m1 stop Fort Lauderdale

2:00 pm - 11:23 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 23m1 stop Fort Lauderdale

$769JetBlue

Wed, Sep 23 - Wed, Sep 30

6:00 am - 12:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

7h 35m1 stop Miami

1:35 pm - 10:57 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 22m1 stop Miami

$769American Airlines

Wed, Sep 23 - Wed, Sep 30

2:13 pm - 12:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

23h 22m2 stops New York LaGuardia Miami

1:35 pm - 9:47 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

19h 12m2 stops Miami Chicago O'Hare Intl

$774American Airlines

Wed, Sep 23 - Wed, Sep 30

6:00 am - 8:00 amDTW Detroit Metropolitan Wayne County-GRU Sao Paulo Guarulhos Intl

49h 00m2 stops Miami Brasilia

8:40 am - 10:57 pmGRU Sao Paulo Guarulhos Intl-DTW Detroit Metropolitan Wayne County

39h 17m2 stops Brasilia Miami

$1,202GOL

Sat, Sep 26 - Sat, Oct 3

2:55 pm - 2:30 pmDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

22h 35m2 stops Toronto Pearson Intl Sao Paulo Guarulhos Intl

4:35 pm - 9:29 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

29h 54m2 stops Sao Paulo Guarulhos Intl Montreal Pierre Elliott Trudeau Intl

$1,231Air Canada

Tue, Sep 22 - Thu, Sep 24

2:00 pm - 2:30 pmDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

23h 30m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Sao Paulo Guarulhos Intl

4:35 pm - 9:29 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

29h 54m2 stops Sao Paulo Guarulhos Intl Montreal Pierre Elliott Trudeau Intl

$1,235Air Canada

Tue, Sep 22 - Thu, Sep 24

2:52 pm - 11:05 amDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

19h 13m2 stops Charlotte Douglas New York John F Kennedy Intl

10:30 pm - 10:59 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

25h 29m1 stop Miami

$1,338GOL

Thu, Sep 24 - Thu, Oct 15

6:20 am - 8:20 pmDTW Detroit Metropolitan Wayne County-LIM Lima J Chavez Intl

15h 00m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

12:05 am - 3:02 pmLIM Lima J Chavez Intl-DTW Detroit Metropolitan Wayne County

13h 57m1 stop New York John F Kennedy Intl

$1,451LATAM Airlines

Thu, Sep 24 - Tue, Oct 20

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United Airlines flights from Detroit to South America

Our best United Airlines deals on Detroit to South America flight tickets

United Airlines

Nov 1

DTW7:26 amDetroit Metropolitan Wayne County

38h 44m

2 stops

MDE10:10 pmMedellín Jose Maria Cordova Intl

Nov 8

MDE10:40 amMedellín Jose Maria Cordova Intl

12h 16m

1 stop

DTW10:56 pmDetroit Metropolitan Wayne County

$527

United Airlines

Nov 1

DTW7:26 amDetroit Metropolitan Wayne County

38h 44m

2 stops

MDE10:10 pmMedellín Jose Maria Cordova Intl

Nov 8

MDE10:40 amMedellín Jose Maria Cordova Intl

33h 50m

2 stops

DTW8:30 pmDetroit Metropolitan Wayne County

$533

United Airlines

Nov 1

DTW8:45 amDetroit Metropolitan Wayne County

13h 25m

1 stop

MDE10:10 pmMedellín Jose Maria Cordova Intl

Nov 8

MDE10:40 amMedellín Jose Maria Cordova Intl

12h 16m

1 stop

DTW10:56 pmDetroit Metropolitan Wayne County

$571

American Airlines flights from Detroit to South America

Our best American Airlines deals on Detroit to South America flight tickets

American Airlines

Nov 9

DTW6:00 amDetroit Metropolitan Wayne County

7h 35m

1 stop

CTG1:35 pmCartagena Rafael Nunez

Nov 17

CTG4:37 pmCartagena Rafael Nunez

17h 53m

2 stops

DTW10:30 amDetroit Metropolitan Wayne County

$430

American Airlines

Oct 24

DTW4:59 pmDetroit Metropolitan Wayne County

20h 36m

2 stops

CTG12:35 pmCartagena Rafael Nunez

Oct 28

CTG1:35 pmCartagena Rafael Nunez

8h 24m

1 stop

DTW10:59 pmDetroit Metropolitan Wayne County

$442

American Airlines

Mar 2

DTW5:35 amDetroit Metropolitan Wayne County

7h 55m

1 stop

CTG1:30 pmCartagena Rafael Nunez

Mar 9

CTG2:30 pmCartagena Rafael Nunez

18h 55m

2 stops

DTW9:25 amDetroit Metropolitan Wayne County

$443

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 11/9

9:10 pm-3:36 pm

2 stops18h 26m

Cartagena Rafael Nunez

Tue 11/17

4:37 pm-10:30 am

2 stops17h 53m

$430

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 11/9

6:00 am-3:36 pm

1 stop9h 36m

Cartagena Rafael Nunez

Tue 11/17

2:35 pm-10:55 pm

1 stop8h 20m

$430

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/20

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Thu 10/22

12:37 pm-9:41 pm

1 stop8h 04m

$437

Quickest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/20

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Wed 10/28

12:44 pm-9:42 pm

1 stop7h 58m

$437

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 3/2

6:00 am-12:34 pm

1 stop6h 34m

Cartagena Rafael Nunez

Tue 3/9

3:30 pm-9:28 am

1 stop17h 58m

$507

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Thu 1/28

12:31 pm-10:10 pm

2 stops33h 39m

Medellín Jose Maria Cordova Intl

Thu 2/4

10:40 am-10:37 pm

1 stop11h 57m

$527

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Sun 11/1

7:26 am-10:10 pm

2 stops38h 44m

Medellín Jose Maria Cordova Intl

Sun 11/8

10:40 am-10:56 pm

1 stop12h 16m

$527

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/20

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Thu 10/22

4:30 am-10:02 pm

2 stops16h 32m

$529

DetroitBogotá

DTW Detroit Metropolitan Wayne County - BOG Bogotá El Dorado

DTWBOG

Detroit Metropolitan Wayne County

Mon 11/23

8:25 am-7:30 pm

1 stop11h 05m

Bogotá El Dorado

Tue 12/8

6:35 pm-11:25 am

2 stops16h 50m

$775

DetroitBogotá

DTW Detroit Metropolitan Wayne County - BOG Bogotá El Dorado

DTWBOG

Detroit Metropolitan Wayne County

Thu 11/26

8:25 am-8:10 pm

2 stops11h 45m

Bogotá El Dorado

Thu 12/3

3:55 pm-9:34 am

1 stop17h 39m

$780

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $621. If you aren’t able to travel during the month of February, then book flights to South America from Detroit during January instead. Flights to South America in January, while not as cheap as those in February, still average around $644.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $829 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $602 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 49% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Best Price Found	$192
Fastest flight time	6h 34m
Direct flights	None

The best one-way flight to South America from Detroit in the past 72 hours is $192. The best round-trip flight deal from Detroit to South America found on momondo in the last 72 hours is $430.

The fastest flight from Detroit to South America takes 6h 34m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

Frequently asked questions about flying from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of September 2026, there are 8 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $217	Free Cancellation	Rating 7.8 8,597 reviews	Search Delta flights
American Airlines	PriceFrom $295	Free Cancellation	Rating 7.0 12,076 reviews	Search American Airlines flights
JetBlue	PriceFrom $421	Free Cancellation	Rating 7.1 3,036 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $614	Free Cancellation	Rating 7.6 1,541 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $676	Free Cancellation	Rating 7.4 1,980 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $676	Free Cancellation	Rating 7.1 11,663 reviews	Search Air Canada flights
GOL	PriceFrom $981	Free Cancellation	Rating 7.3 1,309 reviews	Search GOL flights
United Airlines	PriceFrom $1,133	Free Cancellation	Rating 7.4 10,222 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.