What is the cheapest airline that flies from Detroit to South America?

United Airlines, JetBlue, and Air Canada are the most popular carriers operating from Detroit to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of August 2026, there are 7 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$194 Cheap Flights from Detroit to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 3:36 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

9h 36m1 stop Miami

2:35 pm - 11:59 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

9h 24m1 stop Miami

$437American Airlines

Tue, Nov 3 - Sat, Nov 21

6:00 am - 3:36 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

9h 36m1 stop Miami

2:35 pm - 10:55 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 20m1 stop Miami

$437American Airlines

Mon, Nov 2 - Wed, Nov 11

6:00 am - 11:44 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 44m1 stop Fort Lauderdale

12:44 pm - 9:42 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

7h 58m1 stop Fort Lauderdale

$437JetBlue

Tue, Oct 27 - Sat, Oct 31

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:37 pm - 9:41 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 04m1 stop Fort Lauderdale

$437JetBlue

Sun, Oct 18 - Fri, Oct 23

11:06 am - 12:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

26h 29m2 stops Charlotte Douglas Miami

1:35 pm - 1:58 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

23h 23m2 stops Miami Chicago O'Hare Intl

$464GOL

Tue, Oct 27 - Sat, Oct 31

6:15 am - 9:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 55m1 stop Houston George Bush Intcntl

9:45 am - 10:27 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 42m1 stop Houston George Bush Intcntl

$467United Airlines

Mon, Oct 19 - Mon, Oct 26

6:15 am - 9:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 55m1 stop Houston George Bush Intcntl

9:45 am - 10:30 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 45m1 stop Houston George Bush Intcntl

$467United Airlines

Sat, Oct 17 - Wed, Oct 21

4:59 pm - 12:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

20h 36m2 stops Charlotte Douglas Miami

1:35 pm - 4:09 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

25h 34m2 stops Miami Chicago O'Hare Intl

$480GOL

Wed, Oct 14 - Mon, Oct 19

6:00 am - 11:44 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 44m1 stop Fort Lauderdale

3:34 pm - 9:27 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

17h 53m1 stop Atlanta Hartsfield-Jackson

$490Multiple Airlines

Tue, Oct 27 - Sat, Nov 14

7:55 pm - 1:55 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

19h 00m1 stop Boston Logan Intl

11:55 pm - 2:15 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

13h 20m1 stop Boston Logan Intl

$589Multiple Airlines

Fri, Oct 2 - Mon, Oct 12

Cheap last minute flights

Enter your travel dates to find the best prices.

6:00 am - 11:35 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 35m1 stop Fort Lauderdale

2:00 pm - 11:23 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 23m1 stop Fort Lauderdale

$644JetBlue

Sun, Aug 30 - Wed, Sep 16

6:00 am - 11:35 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 35m1 stop Fort Lauderdale

2:00 pm - 11:23 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 23m1 stop Fort Lauderdale

$644JetBlue

Mon, Aug 31 - Wed, Sep 16

7:44 am - 8:15 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

13h 31m2 stops Dallas/Fort Worth Miami

6:00 am - 11:56 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

16h 56m2 stops Miami Philadelphia

$663American Airlines

Thu, Aug 27 - Mon, Aug 31

6:00 am - 11:35 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 35m1 stop Fort Lauderdale

2:30 pm - 9:22 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

17h 52m1 stop Atlanta Hartsfield-Jackson

$700Multiple Airlines

Thu, Aug 27 - Thu, Sep 10

9:49 am - 11:00 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

14h 11m2 stops Orlando Panama City Tocumen Intl

2:30 pm - 12:54 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

9h 24m1 stop Atlanta Hartsfield-Jackson

$740Multiple Airlines

Sat, Aug 29 - Thu, Sep 10

6:40 am - 8:15 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

14h 35m2 stops Chicago O'Hare Intl Miami

6:00 am - 11:55 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

16h 55m1 stop Miami

$741American Airlines

Thu, Aug 27 - Mon, Aug 31

10:15 am - 2:30 pmDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

51h 15m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Sao Paulo Guarulhos Intl

9:00 pm - 3:29 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

19h 29m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$1,320Air Canada

Sat, Aug 29 - Mon, Sep 14

10:15 am - 2:30 pmDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

51h 15m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Sao Paulo Guarulhos Intl

9:00 pm - 1:24 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

17h 24m1 stop Houston George Bush Intcntl

$1,320Air Canada

Sat, Aug 29 - Mon, Sep 14

4:24 pm - 1:00 pmDTW Detroit Metropolitan Wayne County-AEP Buenos Aires Jorge Newbery

19h 36m2 stops Miami Brasilia

3:40 am - 10:57 pmAEP Buenos Aires Jorge Newbery-DTW Detroit Metropolitan Wayne County

20h 17m2 stops Brasilia Miami

$1,856GOL

Sat, Aug 29 - Sun, Sep 13

4:30 pm - 1:00 pmDTW Detroit Metropolitan Wayne County-GRU Sao Paulo Guarulhos Intl

19h 30m2 stops Miami Brasilia

6:00 am - 11:55 pmGRU Sao Paulo Guarulhos Intl-DTW Detroit Metropolitan Wayne County

18h 55m2 stops Brasilia Miami

$1,898GOL

Fri, Aug 28 - Sun, Sep 6

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Avianca flights from Detroit to South America

Our best Avianca deals on Detroit to South America flight tickets

Avianca

Oct 1

DTW6:15 amDetroit Metropolitan Wayne County

15h 55m

1 stop

MDE9:10 pmMedellín Jose Maria Cordova Intl

Oct 8

MDE9:45 amMedellín Jose Maria Cordova Intl

11h 45m

1 stop

DTW10:30 pmDetroit Metropolitan Wayne County

$590

Avianca

Oct 3

DTW7:48 pmDetroit Metropolitan Wayne County

17h 12m

2 stops

BOG12:00 pmBogotá El Dorado

Oct 13

BOG2:45 pmBogotá El Dorado

18h 15m

2 stops

DTW10:00 amDetroit Metropolitan Wayne County

$727

American Airlines flights from Detroit to South America

Our best American Airlines deals on Detroit to South America flight tickets

American Airlines

Sep 21

DTW6:00 amDetroit Metropolitan Wayne County

7h 35m

1 stop

CTG12:35 pmCartagena Rafael Nunez

Sep 30

CTG1:35 pmCartagena Rafael Nunez

8h 22m

1 stop

DTW10:57 pmDetroit Metropolitan Wayne County

$437

American Airlines

Oct 27

DTW5:13 pmDetroit Metropolitan Wayne County

20h 22m

2 stops

CTG12:35 pmCartagena Rafael Nunez

Nov 1

CTG4:37 pmCartagena Rafael Nunez

20h 22m

2 stops

DTW12:59 pmDetroit Metropolitan Wayne County

$442

American Airlines

Nov 12

DTW6:56 pmDetroit Metropolitan Wayne County

20h 40m

1 stop

CTG3:36 pmCartagena Rafael Nunez

Nov 16

CTG4:37 pmCartagena Rafael Nunez

20h 22m

2 stops

DTW12:59 pmDetroit Metropolitan Wayne County

$452

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 11/3

6:00 am-3:36 pm

1 stop9h 36m

Cartagena Rafael Nunez

Sat 11/21

2:35 pm-11:59 pm

1 stop9h 24m

$437

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 11/2

6:00 am-3:36 pm

1 stop9h 36m

Cartagena Rafael Nunez

Wed 11/11

2:35 pm-10:55 pm

1 stop8h 20m

$437

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/27

6:00 am-11:44 am

1 stop6h 44m

Cartagena Rafael Nunez

Sat 10/31

12:44 pm-9:42 pm

1 stop7h 58m

$437

Quickest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Sun 10/18

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Fri 10/23

12:37 pm-9:41 pm

1 stop8h 04m

$437

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/27

11:06 am-12:35 pm

2 stops26h 29m

Cartagena Rafael Nunez

Sat 10/31

1:35 pm-1:58 pm

2 stops23h 23m

$464

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Mon 10/19

6:15 am-9:10 pm

1 stop15h 55m

Medellín Jose Maria Cordova Intl

Mon 10/26

9:45 am-10:27 pm

1 stop11h 42m

$467

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Sat 10/17

6:15 am-9:10 pm

1 stop15h 55m

Medellín Jose Maria Cordova Intl

Wed 10/21

9:45 am-10:30 pm

1 stop11h 45m

$467

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Wed 10/14

4:59 pm-12:35 pm

2 stops20h 36m

Cartagena Rafael Nunez

Mon 10/19

1:35 pm-4:09 pm

2 stops25h 34m

$480

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/27

6:00 am-11:44 am

1 stop6h 44m

Cartagena Rafael Nunez

Sat 11/14

3:34 pm-9:27 am

1 stop17h 53m

$490

DetroitBogotá

DTW Detroit Metropolitan Wayne County - BOG Bogotá El Dorado

DTWBOG

Detroit Metropolitan Wayne County

Fri 10/2

7:55 pm-1:55 pm

1 stop19h 00m

Bogotá El Dorado

Mon 10/12

11:55 pm-2:15 pm

1 stop13h 20m

$589

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $616. If you aren’t able to travel during the month of February, then book flights to South America from Detroit during January instead. Flights to South America in January, while not as cheap as those in February, still average around $633.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $851 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $619 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 49% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Best Price Found	$194
Fastest flight time	6h 35m
Direct flights	None

The best one-way flight to South America from Detroit in the past 72 hours is $194. The best round-trip flight deal from Detroit to South America found on momondo in the last 72 hours is $437.

The fastest flight from Detroit to South America takes 6h 35m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

Frequently asked questions about flying from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of August 2026, there are 7 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $217	Free Cancellation	Rating 7.8 8,529 reviews	Search Delta flights
American Airlines	PriceFrom $295	Free Cancellation	Rating 7.1 11,995 reviews	Search American Airlines flights
JetBlue	PriceFrom $326	Free Cancellation	Rating 7.1 3,035 reviews	Search JetBlue flights
LATAM Airlines	PriceFrom $676	Free Cancellation	Rating 7.4 1,990 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $676	Free Cancellation	Rating 7.1 11,539 reviews	Search Air Canada flights
GOL	PriceFrom $981	Free Cancellation	Rating 7.3 1,282 reviews	Search GOL flights
United Airlines	PriceFrom $1,119	Free Cancellation	Rating 7.4 10,125 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.