Cheap flights from Detroit to South America from $115

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
5:00 am - 1:08 pm
DTW
-
MDE
9h 08m
1 stop
Spirit Airlines Logo
2:06 pm - 9:38 am
MDE
-
DTW
18h 32m
1 stop
$264Spirit Airlines
Wed, May 6 - Mon, May 11
Spirit Airlines Logo
5:00 am - 1:13 pm
DTW
-
MDE
9h 13m
1 stop
Spirit Airlines Logo
2:10 pm - 11:59 pm
MDE
-
DTW
8h 49m
1 stop
$281Spirit Airlines
Mon, May 11 - Wed, Aug 19
Spirit Airlines Logo
4:17 pm - 12:21 am
DTW
-
MDE
9h 04m
1 stop
Spirit Airlines Logo
1:17 am - 3:12 pm
MDE
-
DTW
12h 55m
1 stop
$282Spirit Airlines
Thu, Mar 19 - Mon, Mar 23
Spirit Airlines Logo
5:15 am - 12:47 pm
DTW
-
BOG
7h 32m
1 stop
Spirit Airlines Logo
12:45 pm - 11:25 pm
BOG
-
DTW
9h 40m
1 stop
$285Spirit Airlines
Tue, Mar 3 - Tue, Mar 10
Spirit Airlines Logo
8:45 pm - 1:10 pm
DTW
-
CTG
16h 25m
1 stop
Spirit Airlines Logo
2:21 pm - 9:15 am
CTG
-
DTW
18h 54m
1 stop
$288Spirit Airlines
Sun, Feb 22 - Thu, Feb 26
Spirit Airlines Logo
1:45 pm - 1:10 pm
DTW
-
BOG
24h 25m
2 stops
Spirit Airlines Logo
2:05 pm - 11:59 pm
BOG
-
DTW
8h 54m
1 stop
$294Spirit Airlines
Wed, May 13 - Wed, May 20
Spirit Airlines Logo
10:59 pm - 2:10 pm
DTW
-
BOG
15h 11m
2 stops
Spirit Airlines Logo
12:45 pm - 11:25 pm
BOG
-
DTW
9h 40m
1 stop
$299Spirit Airlines
Tue, Mar 3 - Tue, Mar 10
Spirit Airlines Logo
4:17 pm - 12:21 am
DTW
-
MDE
9h 04m
1 stop
Spirit Airlines Logo
10:49 am - 8:33 pm
MDE
-
DTW
8h 44m
1 stop
$302Spirit Airlines
Wed, Mar 18 - Thu, Mar 19
Multiple Airlines Logo
4:09 pm - 12:21 am
DTW
-
MDE
9h 12m
1 stop
Multiple Airlines Logo
1:17 am - 12:29 am
MDE
-
DTW
22h 12m
1 stop
$308Multiple Airlines
Wed, Mar 18 - Mon, Mar 30
Air Canada Logo
6:15 pm - 4:45 pm
DTW
-
SDU
21h 30m
2 stops
Air Canada Logo
1:50 pm - 5:35 pm
SDU
-
DTW
28h 45m
2 stops
$833Air Canada
Mon, Mar 9 - Tue, Mar 17

Spirit Airlines flights from Detroit to South America

Our best Spirit Airlines deals on Detroit to South America flight tickets
Spirit Airlines
May 6
DTW5:00 amDetroit Metropolitan Wayne County
9h 08m
1 stop
MDE1:08 pmMedellín Jose Maria Cordova Intl
May 11
MDE2:06 pmMedellín Jose Maria Cordova Intl
18h 32m
1 stop
DTW9:38 amDetroit Metropolitan Wayne County
$264
Spirit Airlines
May 11
DTW5:00 amDetroit Metropolitan Wayne County
9h 13m
1 stop
MDE1:13 pmMedellín Jose Maria Cordova Intl
Aug 19
MDE2:10 pmMedellín Jose Maria Cordova Intl
8h 49m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$281
Spirit Airlines
Mar 19
DTW4:17 pmDetroit Metropolitan Wayne County
9h 04m
1 stop
MDE12:21 amMedellín Jose Maria Cordova Intl
Mar 23
MDE1:17 amMedellín Jose Maria Cordova Intl
12h 55m
1 stop
DTW3:12 pmDetroit Metropolitan Wayne County
$282

Air Canada flights from Detroit to South America

Our best Air Canada deals on Detroit to South America flight tickets
Air Canada
Mar 1
DTW6:15 pmDetroit Metropolitan Wayne County
14h 20m
1 stop
GRU10:35 amSao Paulo Guarulhos Intl
Mar 11
GRU9:30 pmSao Paulo Guarulhos Intl
21h 05m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$747
Air Canada
May 15
DTW10:15 amDetroit Metropolitan Wayne County
22h 35m
1 stop
GRU9:50 amSao Paulo Guarulhos Intl
May 25
GRU9:00 pmSao Paulo Guarulhos Intl
22h 13m
2 stops
DTW6:13 pmDetroit Metropolitan Wayne County
$750
Air Canada
Mar 8
DTW6:15 pmDetroit Metropolitan Wayne County
15h 20m
1 stop
GRU10:35 amSao Paulo Guarulhos Intl
Mar 18
GRU9:15 pmSao Paulo Guarulhos Intl
21h 20m
2 stops
DTW5:35 pmDetroit Metropolitan Wayne County
$755

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Detroit to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Wed 5/6

5:00 am-1:08 pm

1 stop9h 08m

Medellín Jose Maria Cordova Intl

Mon 5/11

2:06 pm-9:38 am

1 stop18h 32m

$264

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Mon 5/11

5:00 am-1:13 pm

1 stop9h 13m

Medellín Jose Maria Cordova Intl

Wed 8/19

2:10 pm-11:59 pm

1 stop8h 49m

$281

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 3/19

4:17 pm-12:21 am

1 stop9h 04m

Medellín Jose Maria Cordova Intl

Mon 3/23

1:17 am-3:12 pm

1 stop12h 55m

$282

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Tue 3/3

5:15 am-12:47 pm

1 stop7h 32m

Bogotá El Dorado

Tue 3/10

12:45 pm-11:25 pm

1 stop9h 40m

$285

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sun 2/22

8:45 pm-1:10 pm

1 stop16h 25m

Cartagena Rafael Nunez

Thu 2/26

2:21 pm-9:15 am

1 stop18h 54m

$288

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Wed 5/13

1:45 pm-1:10 pm

2 stops24h 25m

Bogotá El Dorado

Wed 5/20

2:05 pm-11:59 pm

1 stop8h 54m

$294

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Tue 3/3

10:59 pm-2:10 pm

2 stops15h 11m

Bogotá El Dorado

Tue 3/10

12:45 pm-11:25 pm

1 stop9h 40m

$299

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Wed 3/18

4:17 pm-12:21 am

1 stop9h 04m

Medellín Jose Maria Cordova Intl

Thu 3/19

10:49 am-8:33 pm

1 stop8h 44m

$302

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Wed 3/18

4:09 pm-12:21 am

1 stop9h 12m

Medellín Jose Maria Cordova Intl

Mon 3/30

1:17 am-12:29 am

1 stop22h 12m

$308

DetroitRio de Janeiro

DTW - SDU

DTWSDU

Detroit Metropolitan Wayne County

Mon 3/9

6:15 pm-4:45 pm

2 stops21h 30m

Rio de Janeiro Santos Dumont

Tue 3/17

1:50 pm-5:35 pm

2 stops28h 45m

$833

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $524. If you aren’t able to travel during the month of September, then book flights to South America from Detroit during August instead. Flights to South America in August, while not as cheap as those in September, still average around $624.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $894 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $589 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 29% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time

7h 21m

Direct flights

None
The fastest flight from Detroit to South America takes 7h 21m
There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.
  • When did momondo last update prices for flights from Detroit to South America?

    Prices for flights from Detroit to South America refresh daily.

  • How many operators does momondo search for flights from Detroit to South America?

  • How old do you have to be to fly from Detroit to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $105Free CancellationRating
6.3
8,451 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $385Free CancellationRating
7.2
11,283 reviews
Search American Airlines flights
DeltaPriceFrom $527Free CancellationRating
7.9
8,198 reviews
Search Delta flights
Air CanadaPriceFrom $585Free CancellationRating
7.1
10,717 reviews
Search Air Canada flights
LATAM AirlinesPriceFrom $643Free CancellationRating
7.5
1,920 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $699Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $801Free CancellationRating
7.4
9,287 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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1 adult
Sun 3/15
Sun 3/22

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