What airlines fly to South America?

Spirit Airlines, Delta and American Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Spirit Airlines is the first choice among our users, with 30% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Detroit to South America?

Spirit Airlines, Air Canada, and United Airlines are the most popular carriers operating from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of December 2025, there are 7 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$107 Cheap Flights from Detroit to South America in 2025/26

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Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:30 am - 1:15 pmDTW-CTG

7h 45m1 stop

2:21 pm - 10:44 pmCTG-DTW

8h 23m1 stop

$246Spirit Airlines

Find Deal

Wed, Jan 21 - Wed, Jan 28

10:54 am - 2:15 pmDTW-MDE

27h 21m1 stop

3:15 pm - 10:02 pmMDE-DTW

30h 47m1 stop

$270Multiple Airlines

Find Deal

Thu, Feb 5 - Wed, Feb 11

1:43 pm - 2:15 pmDTW-MDE

24h 32m1 stop

3:15 pm - 10:35 amMDE-DTW

43h 20m2 stops

$278Multiple Airlines

Find Deal

Sun, Feb 1 - Sat, Feb 7

5:30 am - 1:15 pmDTW-CTG

7h 45m1 stop

2:21 pm - 10:44 pmCTG-DTW

8h 23m1 stop

$283Spirit Airlines

Find Deal

Sat, Jan 17 - Sat, Jan 24

5:30 am - 2:15 pmDTW-MDE

8h 45m1 stop

3:15 pm - 10:05 amMDE-DTW

18h 50m1 stop

$284Spirit Airlines

Find Deal

Wed, Jan 28 - Wed, Feb 4

6:36 pm - 2:15 pmDTW-MDE

19h 39m1 stop

3:15 pm - 10:02 pmMDE-DTW

30h 47m1 stop

$286Multiple Airlines

Find Deal

Mon, Feb 9 - Wed, Feb 11

5:30 am - 2:15 pmDTW-MDE

8h 45m1 stop

3:15 pm - 10:05 amMDE-DTW

18h 50m1 stop

$290Spirit Airlines

Find Deal

Mon, Feb 9 - Tue, Feb 10

5:30 am - 2:15 pmDTW-MDE

8h 45m1 stop

3:15 pm - 10:05 amMDE-DTW

18h 50m1 stop

$297Spirit Airlines

Find Deal

Fri, Feb 6 - Tue, Feb 10

5:30 am - 1:15 pmDTW-CTG

7h 45m1 stop

2:21 pm - 10:44 pmCTG-DTW

8h 23m1 stop

$299Spirit Airlines

Find Deal

Mon, Jan 26 - Fri, Jan 30

6:36 pm - 2:15 pmDTW-MDE

19h 39m1 stop

3:15 pm - 10:05 amMDE-DTW

18h 50m1 stop

$299Spirit Airlines

Find Deal

Sat, Feb 7 - Tue, Feb 10

Spirit Airlines flights from Detroit to South America

Our best Spirit Airlines deals on Detroit to South America flight tickets

Spirit Airlines

Dec 8

DTW6:00 amDetroit Metropolitan Wayne County

7h 10m

1 stop

CTG1:10 pmCartagena Rafael Nunez

Dec 12

CTG2:15 pmCartagena Rafael Nunez

10h 04m

1 stop

DTW12:19 amDetroit Metropolitan Wayne County

$221

Find similar

Spirit Airlines

Dec 8

DTW6:00 amDetroit Metropolitan Wayne County

7h 10m

1 stop

CTG1:10 pmCartagena Rafael Nunez

Dec 12

CTG2:15 pmCartagena Rafael Nunez

17h 52m

2 stops

DTW8:07 amDetroit Metropolitan Wayne County

$242

Find similar

Spirit Airlines

Jan 21

DTW5:30 amDetroit Metropolitan Wayne County

7h 45m

1 stop

CTG1:15 pmCartagena Rafael Nunez

Jan 28

CTG2:21 pmCartagena Rafael Nunez

8h 23m

1 stop

DTW10:44 pmDetroit Metropolitan Wayne County

$246

Find similar

Delta flights from Detroit to South America

Our best Delta deals on Detroit to South America flight tickets

Delta

May 4

DTW9:25 amDetroit Metropolitan Wayne County

11h 44m

1 stop

UIO8:09 pmQuito Mariscal Sucr

May 14

UIO11:20 pmQuito Mariscal Sucr

9h 04m

1 stop

DTW9:24 amDetroit Metropolitan Wayne County

$705

Find similar

Delta

Dec 8

DTW8:11 amDetroit Metropolitan Wayne County

11h 19m

1 stop

BOG7:30 pmBogotá El Dorado

Dec 16

BOG9:00 amBogotá El Dorado

9h 46m

1 stop

DTW6:46 pmDetroit Metropolitan Wayne County

$953

Find similar

Delta

Dec 10

DTW7:11 amDetroit Metropolitan Wayne County

12h 19m

1 stop

BOG7:30 pmBogotá El Dorado

Dec 16

BOG3:55 pmBogotá El Dorado

8h 44m

1 stop

DTW12:39 amDetroit Metropolitan Wayne County

$1,008

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Wed 1/21

5:30 am-1:15 pm

1 stop7h 45m

Cartagena Rafael Nunez

Wed 1/28

2:21 pm-10:44 pm

1 stop8h 23m

$246

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Thu 2/5

10:54 am-2:15 pm

1 stop27h 21m

Medellín Jose Maria Cordova Intl

Wed 2/11

3:15 pm-10:02 pm

1 stop30h 47m

$270

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sun 2/1

1:43 pm-2:15 pm

1 stop24h 32m

Medellín Jose Maria Cordova Intl

Sat 2/7

3:15 pm-10:35 am

2 stops43h 20m

$278

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 1/17

5:30 am-1:15 pm

1 stop7h 45m

Cartagena Rafael Nunez

Sat 1/24

2:21 pm-10:44 pm

1 stop8h 23m

$283

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Wed 1/28

5:30 am-2:15 pm

1 stop8h 45m

Medellín Jose Maria Cordova Intl

Wed 2/4

3:15 pm-10:05 am

1 stop18h 50m

$284

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Mon 2/9

6:36 pm-2:15 pm

1 stop19h 39m

Medellín Jose Maria Cordova Intl

Wed 2/11

3:15 pm-10:02 pm

1 stop30h 47m

$286

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Mon 2/9

5:30 am-2:15 pm

1 stop8h 45m

Medellín Jose Maria Cordova Intl

Tue 2/10

3:15 pm-10:05 am

1 stop18h 50m

$290

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Fri 2/6

5:30 am-2:15 pm

1 stop8h 45m

Medellín Jose Maria Cordova Intl

Tue 2/10

3:15 pm-10:05 am

1 stop18h 50m

$297

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Mon 1/26

5:30 am-1:15 pm

1 stop7h 45m

Cartagena Rafael Nunez

Fri 1/30

2:21 pm-10:44 pm

1 stop8h 23m

$299

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sat 2/7

6:36 pm-2:15 pm

1 stop19h 39m

Medellín Jose Maria Cordova Intl

Tue 2/10

3:15 pm-10:05 am

1 stop18h 50m

$299

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $524. If you aren’t able to travel during the month of September, then book flights to South America from Detroit during August instead. Flights to South America in August, while not as cheap as those in September, still average around $622.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Detroit to South America is on a Tuesday when prices can be found for as low as $793. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Detroit to South America for around $999.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Detroit to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $923. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $954 on average. Flights to South America from Detroit in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $972 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $671 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 19% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time	7h 10m
Direct flights	None

The fastest flight from Detroit to South America takes 7h 10m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of December 2025, there are 7 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $104	Free Cancellation	Rating 6.3 8,156 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $385	Free Cancellation	Rating 7.2 11,045 reviews	Search American Airlines flights
Delta	PriceFrom $527	Free Cancellation	Rating 7.9 8,011 reviews	Search Delta flights
United Airlines	PriceFrom $550	Free Cancellation	Rating 7.4 9,063 reviews	Search United Airlines flights
Air Canada	PriceFrom $585	Free Cancellation	Rating 7.1 10,496 reviews	Search Air Canada flights
LATAM Airlines	PriceFrom $652	Free Cancellation	Rating 7.5 1,890 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $699	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.