What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Delta is the first choice among our users, with 42% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Detroit to South America?

JetBlue, American Airlines, and Air Canada are the most popular carriers operating from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of June 2026, there are 7 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$182 Cheap Flights from Detroit to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 2:20 pm

DTW

MDE

8h 20m

1 stop

1:30 pm - 11:30 pm

MDE

DTW

9h 00m

1 stop

$364JetBlue

Sat, Sep 12 - Fri, Sep 18

7:00 am - 2:20 pm

DTW

MDE

8h 20m

1 stop

1:30 pm - 11:30 pm

MDE

DTW

9h 00m

1 stop

$365JetBlue

Sat, Sep 12 - Wed, Sep 16

7:00 am - 2:20 pm

DTW

MDE

8h 20m

1 stop

1:30 pm - 11:30 pm

MDE

DTW

9h 00m

1 stop

$373JetBlue

Mon, Sep 14 - Thu, Sep 17

6:00 am - 12:35 pm

DTW

CTG

7h 35m

1 stop

1:35 pm - 10:57 pm

CTG

DTW

8h 22m

1 stop

$421American Airlines

Wed, Sep 9 - Wed, Sep 16

10:08 am - 6:00 pm

DTW

BOG

8h 52m

1 stop

10:35 pm - 5:22 pm

BOG

DTW

17h 47m

2 stops

$443Multiple Airlines

Fri, Aug 14 - Fri, Aug 21

5:41 am - 10:34 pm

DTW

BOG

17h 53m

1 stop

12:25 am - 3:08 pm

BOG

DTW

13h 43m

1 stop

$533American Airlines

Tue, Sep 1 - Mon, Sep 14

3:55 pm - 3:15 am

DTW

LIM

11h 20m

1 stop

8:00 am - 3:12 pm

LIM

DTW

31h 12m

2 stops

$558Air Canada

Fri, Nov 27 - Fri, Dec 4

3:55 pm - 3:15 am

DTW

LIM

11h 20m

1 stop

1:50 am - 3:12 pm

LIM

DTW

37h 22m

2 stops

$559Multiple Airlines

Fri, Nov 13 - Tue, Nov 17

3:55 pm - 6:10 am

DTW

LIM

38h 15m

2 stops

8:00 am - 3:12 pm

LIM

DTW

31h 12m

2 stops

$566Air Canada

Fri, Nov 27 - Fri, Dec 4

2:32 pm - 10:00 pm

DTW

LIM

32h 28m

1 stop

12:30 pm - 9:23 am

LIM

DTW

19h 53m

2 stops

$747LATAM Airlines

Wed, Sep 16 - Wed, Sep 23

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United Airlines flights from Detroit to South America

Our best United Airlines deals on Detroit to South America flight tickets

United Airlines

Oct 4

DTW6:55 pmDetroit Metropolitan Wayne County

25h 25m

1 stop

BOG7:20 pmBogotá El Dorado

Oct 15

BOG8:30 amBogotá El Dorado

13h 00m

1 stop

DTW10:30 pmDetroit Metropolitan Wayne County

$616

United Airlines

Dec 5

DTW4:43 pmDetroit Metropolitan Wayne County

31h 47m

1 stop

UIO12:30 amQuito Mariscal Sucr

Dec 13

UIO1:35 amQuito Mariscal Sucr

14h 08m

1 stop

DTW3:43 pmDetroit Metropolitan Wayne County

$821

United Airlines

Jun 25

DTW6:15 amDetroit Metropolitan Wayne County

23h 45m

1 stop

UIO5:00 amQuito Mariscal Sucr

Aug 16

UIO7:25 amQuito Mariscal Sucr

25h 13m

2 stops

DTW9:38 amDetroit Metropolitan Wayne County

$1,043

LATAM Airlines flights from Detroit to South America

Our best LATAM Airlines deals on Detroit to South America flight tickets

LATAM Airlines

Sep 7

DTW9:09 amDetroit Metropolitan Wayne County

25h 26m

2 stops

CTG9:35 amCartagena Rafael Nunez

Sep 17

CTG2:30 pmCartagena Rafael Nunez

9h 24m

1 stop

DTW12:54 amDetroit Metropolitan Wayne County

$556

LATAM Airlines

Sep 1

DTW9:09 amDetroit Metropolitan Wayne County

12h 01m

1 stop

BOG8:10 pmBogotá El Dorado

Sep 17

BOG8:40 amBogotá El Dorado

11h 40m

1 stop

DTW9:20 pmDetroit Metropolitan Wayne County

$583

LATAM Airlines

Nov 23

DTW6:30 amDetroit Metropolitan Wayne County

13h 00m

1 stop

BOG7:30 pmBogotá El Dorado

Dec 8

BOG7:00 amBogotá El Dorado

14h 40m

1 stop

DTW9:40 pmDetroit Metropolitan Wayne County

$678

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sat 9/12

7:00 am-2:20 pm

1 stop8h 20m

Medellín Jose Maria Cordova Intl

Fri 9/18

1:30 pm-11:30 pm

1 stop9h 00m

$364

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sat 9/12

7:00 am-2:20 pm

1 stop8h 20m

Medellín Jose Maria Cordova Intl

Wed 9/16

1:30 pm-11:30 pm

1 stop9h 00m

$365

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Mon 9/14

7:00 am-2:20 pm

1 stop8h 20m

Medellín Jose Maria Cordova Intl

Thu 9/17

1:30 pm-11:30 pm

1 stop9h 00m

$373

Quickest round-trip

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Wed 9/9

6:00 am-12:35 pm

1 stop7h 35m

Cartagena Rafael Nunez

Wed 9/16

1:35 pm-10:57 pm

1 stop8h 22m

$421

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Fri 8/14

10:08 am-6:00 pm

1 stop8h 52m

Bogotá El Dorado

Fri 8/21

10:35 pm-5:22 pm

2 stops17h 47m

$443

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Tue 9/1

5:41 am-10:34 pm

1 stop17h 53m

Bogotá El Dorado

Mon 9/14

12:25 am-3:08 pm

1 stop13h 43m

$533

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Fri 11/27

3:55 pm-3:15 am

1 stop11h 20m

Lima J Chavez Intl

Fri 12/4

8:00 am-3:12 pm

2 stops31h 12m

$558

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Fri 11/13

3:55 pm-3:15 am

1 stop11h 20m

Lima J Chavez Intl

Tue 11/17

1:50 am-3:12 pm

2 stops37h 22m

$559

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Fri 11/27

3:55 pm-6:10 am

2 stops38h 15m

Lima J Chavez Intl

Fri 12/4

8:00 am-3:12 pm

2 stops31h 12m

$566

DetroitLima

DTW - LIM

DTWLIM

Detroit Metropolitan Wayne County

Wed 9/16

2:32 pm-10:00 pm

1 stop32h 28m

Lima J Chavez Intl

Wed 9/23

12:30 pm-9:23 am

2 stops19h 53m

$747

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $105. If you aren’t able to travel during the month of October, then book flights to South America from Detroit during November instead. Flights to South America in November, while not as cheap as those in October, still average around $159.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $818 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $417 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 33% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time	6h 30m
Direct flights	None

The fastest flight from Detroit to South America takes 6h 30m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

Frequently asked questions about flying from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of June 2026, there are 7 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $235	Free Cancellation	Rating 7.8 8,423 reviews	Search Delta flights
JetBlue	PriceFrom $428	Free Cancellation	Rating 7.1 2,990 reviews	Search JetBlue flights
American Airlines	PriceFrom $452	Free Cancellation	Rating 7.1 11,722 reviews	Search American Airlines flights
Copa Airlines	PriceFrom $650	Free Cancellation	Rating 7.6 1,569 reviews	Search Copa Airlines flights
Air Canada	PriceFrom $681	Free Cancellation	Rating 7.1 11,231 reviews	Search Air Canada flights
LATAM Airlines	PriceFrom $730	Free Cancellation	Rating 7.4 1,940 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $1,119	Free Cancellation	Rating 7.4 9,868 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.