What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Delta is the first choice among our users, with 35% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Detroit to South America?

Copa Airlines, Frontier, and JetBlue are the most popular carriers operating from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of October 2026, there are 8 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$233 Cheap Flights from Detroit to South America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 11:30 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

29h 30m1 stop Orlando

12:45 pm - 1:07 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

12h 22m1 stop Orlando

$460Frontier

Fri, Jan 29 - Sat, Feb 6

8:17 pm - 11:05 amDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

14h 48m1 stop Orlando

3:20 pm - 1:07 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

9h 47m1 stop Orlando

$493Frontier

Wed, Feb 24 - Wed, Mar 3

6:00 am - 12:09 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

7h 09m1 stop Miami

1:25 pm - 11:57 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

9h 32m1 stop Miami

$629American Airlines

Sat, Apr 17 - Sat, Apr 24

5:23 am - 3:34 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

10h 11m1 stop Miami

2:43 pm - 11:57 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

9h 14m1 stop Miami

$629American Airlines

Sun, Feb 21 - Thu, Feb 25

5:20 am - 7:30 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

15h 10m1 stop Atlanta Hartsfield-Jackson

3:55 pm - 9:28 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

16h 33m1 stop Atlanta Hartsfield-Jackson

$690Delta

Wed, Mar 17 - Mon, Apr 5

10:30 am - 7:30 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

10h 00m1 stop Atlanta Hartsfield-Jackson

3:55 pm - 10:29 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

17h 34m1 stop Atlanta Hartsfield-Jackson

$690Delta

Tue, Mar 16 - Thu, Apr 1

6:00 am - 12:43 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 43m1 stop Fort Lauderdale

1:50 pm - 9:57 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 07m1 stop Fort Lauderdale

$707JetBlue

Tue, Nov 17 - Fri, Nov 20

7:30 am - 6:59 pmDTW Detroit Metropolitan Wayne County-UIO Quito Mariscal Sucr

12h 29m1 stop Atlanta Hartsfield-Jackson

8:55 am - 9:40 pmUIO Quito Mariscal Sucr-DTW Detroit Metropolitan Wayne County

11h 45m1 stop Miami

$758LATAM Airlines

Wed, Mar 31 - Thu, Apr 8

7:30 am - 6:59 pmDTW Detroit Metropolitan Wayne County-UIO Quito Mariscal Sucr

12h 29m1 stop Atlanta Hartsfield-Jackson

7:05 am - 9:40 pmUIO Quito Mariscal Sucr-DTW Detroit Metropolitan Wayne County

13h 35m2 stops Bogotá El Dorado Miami

$788LATAM Airlines

Wed, Mar 31 - Thu, Apr 8

6:00 am - 12:43 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 43m1 stop Fort Lauderdale

1:49 pm - 9:42 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

7h 53m1 stop Fort Lauderdale

$869JetBlue

Sat, Nov 7 - Sat, Nov 14

Cheap last minute flights

Enter your travel dates to find the best prices.

4:29 pm - 6:20 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

26h 51m2 stops Fort Lauderdale San Juan Luis Munoz Marin Intl

5:20 am - 2:06 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

32h 46m3 stops Bogotá El Dorado San Juan Luis Munoz Marin Intl Philadelphia

$651Multiple Airlines

Sat, Oct 24 - Sun, Nov 1

10:13 am - 10:55 amDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

25h 42m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

9:15 am - 10:18 amMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

25h 03m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

$659Copa Airlines

Tue, Oct 27 - Wed, Nov 18

4:29 pm - 6:20 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

26h 51m2 stops Fort Lauderdale San Juan Luis Munoz Marin Intl

11:25 am - 2:06 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

26h 41m2 stops San Juan Luis Munoz Marin Intl Philadelphia

$669Multiple Airlines

Sat, Oct 24 - Sun, Nov 1

5:45 am - 5:00 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

12h 15m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

5:00 am - 8:30 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

15h 30m2 stops Panama City Tocumen Intl Chicago O'Hare Intl

$720Copa Airlines

Tue, Oct 27 - Wed, Nov 18

11:00 am - 7:20 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

9h 20m1 stop Houston George Bush Intcntl

1:30 am - 10:27 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

19h 57m1 stop Houston George Bush Intcntl

$731United Airlines

Fri, Oct 23 - Mon, Oct 26

7:00 am - 10:00 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

16h 00m1 stop Newark

1:30 am - 10:27 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

19h 57m1 stop Houston George Bush Intcntl

$731United Airlines

Fri, Oct 23 - Wed, Oct 28

6:00 am - 8:15 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 15m1 stop Miami

7:30 am - 10:55 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

15h 25m1 stop Miami

$751American Airlines

Tue, Oct 27 - Wed, Nov 18

6:06 am - 8:15 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 09m2 stops New York LaGuardia Miami

7:30 am - 10:55 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

15h 25m1 stop Miami

$755American Airlines

Tue, Oct 27 - Wed, Nov 18

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

1:49 pm - 9:42 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

7h 53m1 stop Fort Lauderdale

$1,184JetBlue

Fri, Oct 23 - Sun, Nov 1

6:00 am - 6:20 amDTW Detroit Metropolitan Wayne County-GRU Sao Paulo Guarulhos Intl

23h 20m1 stop Miami

12:05 am - 6:26 pmGRU Sao Paulo Guarulhos Intl-DTW Detroit Metropolitan Wayne County

20h 21m1 stop Miami

$1,516GOL

Sat, Oct 24 - Sun, Nov 1

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United Airlines flights from Detroit to South America

Our best United Airlines deals on Detroit to South America flight tickets

United Airlines

Nov 18

DTW7:26 amDetroit Metropolitan Wayne County

15h 09m

2 stops

BOG10:35 pmBogotá El Dorado

Nov 24

BOG8:15 amBogotá El Dorado

14h 07m

2 stops

DTW10:22 pmDetroit Metropolitan Wayne County

$684

United Airlines

Nov 18

DTW6:15 amDetroit Metropolitan Wayne County

16h 20m

2 stops

BOG10:35 pmBogotá El Dorado

Dec 7

BOG8:15 amBogotá El Dorado

13h 59m

2 stops

DTW10:14 pmDetroit Metropolitan Wayne County

$697

United Airlines

Nov 9

DTW4:10 pmDetroit Metropolitan Wayne County

13h 00m

2 stops

BOG5:10 amBogotá El Dorado

Nov 16

BOG9:45 amBogotá El Dorado

11h 13m

1 stop

DTW8:58 pmDetroit Metropolitan Wayne County

$699

Air Canada flights from Detroit to South America

Our best Air Canada deals on Detroit to South America flight tickets

Air Canada

Mar 26

DTW6:20 pmDetroit Metropolitan Wayne County

20h 25m

1 stop

CTG1:45 pmCartagena Rafael Nunez

Apr 3

CTG2:45 pmCartagena Rafael Nunez

25h 53m

1 stop

DTW5:38 pmDetroit Metropolitan Wayne County

$638

Air Canada

Mar 26

DTW6:20 pmDetroit Metropolitan Wayne County

20h 25m

1 stop

CTG1:45 pmCartagena Rafael Nunez

Apr 3

CTG2:45 pmCartagena Rafael Nunez

25h 53m

1 stop

DTW5:38 pmDetroit Metropolitan Wayne County

$672

Air Canada

Mar 10

DTW6:20 pmDetroit Metropolitan Wayne County

11h 00m

1 stop

BOG5:20 amBogotá El Dorado

Mar 24

BOG8:45 amBogotá El Dorado

31h 54m

2 stops

DTW5:39 pmDetroit Metropolitan Wayne County

$678

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Fri 1/29

6:00 am-11:30 am

1 stop29h 30m

Cartagena Rafael Nunez

Sat 2/6

12:45 pm-1:07 am

1 stop12h 22m

$460

DetroitBogotá

DTW Detroit Metropolitan Wayne County - BOG Bogotá El Dorado

DTWBOG

Detroit Metropolitan Wayne County

Wed 2/24

8:17 pm-11:05 am

1 stop14h 48m

Bogotá El Dorado

Wed 3/3

3:20 pm-1:07 am

1 stop9h 47m

$493

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Sat 4/17

6:00 am-12:09 pm

1 stop7h 09m

Cartagena Rafael Nunez

Sat 4/24

1:25 pm-11:57 pm

1 stop9h 32m

$629

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Sun 2/21

5:23 am-3:34 pm

1 stop10h 11m

Cartagena Rafael Nunez

Thu 2/25

2:43 pm-11:57 pm

1 stop9h 14m

$629

DetroitBogotá

DTW Detroit Metropolitan Wayne County - BOG Bogotá El Dorado

DTWBOG

Detroit Metropolitan Wayne County

Wed 3/17

5:20 am-7:30 pm

1 stop15h 10m

Bogotá El Dorado

Mon 4/5

3:55 pm-9:28 am

1 stop16h 33m

$690

DetroitBogotá

DTW Detroit Metropolitan Wayne County - BOG Bogotá El Dorado

DTWBOG

Detroit Metropolitan Wayne County

Tue 3/16

10:30 am-7:30 pm

1 stop10h 00m

Bogotá El Dorado

Thu 4/1

3:55 pm-10:29 am

1 stop17h 34m

$690

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 11/17

6:00 am-12:43 pm

1 stop6h 43m

Cartagena Rafael Nunez

Fri 11/20

1:50 pm-9:57 pm

1 stop8h 07m

$707

DetroitQuito

DTW Detroit Metropolitan Wayne County - UIO Quito Mariscal Sucr

DTWUIO

Detroit Metropolitan Wayne County

Wed 3/31

7:30 am-6:59 pm

1 stop12h 29m

Quito Mariscal Sucr

Thu 4/8

8:55 am-9:40 pm

1 stop11h 45m

$758

DetroitQuito

DTW Detroit Metropolitan Wayne County - UIO Quito Mariscal Sucr

DTWUIO

Detroit Metropolitan Wayne County

Wed 3/31

7:30 am-6:59 pm

1 stop12h 29m

Quito Mariscal Sucr

Thu 4/8

7:05 am-9:40 pm

2 stops13h 35m

$788

Quickest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Sat 11/7

6:00 am-12:43 pm

1 stop6h 43m

Cartagena Rafael Nunez

Sat 11/14

1:49 pm-9:42 pm

1 stop7h 53m

$869

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $690. If you aren’t able to travel during the month of April, then book flights to South America from Detroit during January instead. Flights to South America in January, while not as cheap as those in April, still average around $714.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $822 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $602 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 46% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Best Price Found	$233
Fastest flight time	6h 43m
Direct flights	None

The best one-way flight to South America from Detroit in the past 72 hours is $233. The best round-trip flight deal from Detroit to South America found on momondo in the last 72 hours is $460.

The fastest flight from Detroit to South America takes 6h 43m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

Frequently asked questions about flying from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of October 2026, there are 8 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $217	Free Cancellation	Rating 7.8 8,667 reviews	Search Delta flights
American Airlines	PriceFrom $299	Free Cancellation	Rating 7.0 12,193 reviews	Search American Airlines flights
JetBlue	PriceFrom $421	Free Cancellation	Rating 7.1 3,062 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $614	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $676	Free Cancellation	Rating 7.4 1,971 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $676	Free Cancellation	Rating 7.1 11,794 reviews	Search Air Canada flights
GOL	PriceFrom $981	Free Cancellation	Rating 7.3 1,326 reviews	Search GOL flights
United Airlines	PriceFrom $1,251	Free Cancellation	Rating 7.3 10,408 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.