Cheap flights from Detroit to South America from $196

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to South America departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:05 pm - 12:26 pm
DTW
-
CTG
19h 21m
2 stops
Multiple Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$392Multiple Airlines
Wed, May 27 - Wed, Jun 3
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$394Spirit Airlines
Wed, Jun 10 - Wed, Jun 17
Spirit Airlines Logo
6:00 am - 12:26 pm
DTW
-
CTG
7h 26m
1 stop
Spirit Airlines Logo
1:31 pm - 11:53 pm
CTG
-
DTW
9h 22m
1 stop
$395Spirit Airlines
Wed, May 27 - Thu, Jun 4
Air Canada Logo
10:15 am - 4:05 am
DTW
-
BOG
18h 50m
1 stop
Air Canada Logo
9:00 am - 9:25 pm
BOG
-
DTW
11h 25m
1 stop
$563Air Canada
Sat, May 9 - Sat, May 16
Air Canada Logo
10:05 am - 2:30 pm
DTW
-
EZE
27h 25m
2 stops
Air Canada Logo
4:35 pm - 9:29 pm
EZE
-
DTW
29h 54m
2 stops
$971Air Canada
Fri, Sep 11 - Mon, Sep 21
LATAM Airlines Logo
7:45 pm - 10:00 am
DTW
-
CUZ
15h 15m
2 stops
LATAM Airlines Logo
6:10 pm - 3:11 pm
CUZ
-
DTW
20h 01m
2 stops
$1,013LATAM Airlines
Mon, Oct 5 - Mon, Oct 12
LATAM Airlines Logo
6:30 pm - 1:35 pm
DTW
-
CUZ
20h 05m
2 stops
LATAM Airlines Logo
6:10 pm - 3:11 pm
CUZ
-
DTW
20h 01m
2 stops
$1,053LATAM Airlines
Thu, Oct 15 - Sun, Oct 25
Delta Logo
8:25 am - 1:00 am
DTW
-
CUZ
17h 35m
2 stops
Delta Logo
8:35 am - 3:11 pm
CUZ
-
DTW
29h 36m
2 stops
$1,069Delta
Sat, Aug 15 - Mon, Aug 24
American Airlines Logo
6:00 am - 7:20 am
DTW
-
CUZ
26h 20m
2 stops
American Airlines Logo
8:05 pm - 3:55 pm
CUZ
-
DTW
18h 50m
2 stops
$1,070American Airlines
Mon, Aug 3 - Thu, Aug 13
American Airlines Logo
6:00 am - 7:20 am
DTW
-
CUZ
26h 20m
2 stops
American Airlines Logo
8:05 pm - 3:55 pm
CUZ
-
DTW
18h 50m
2 stops
$1,108American Airlines
Mon, Aug 3 - Thu, Aug 13

Air Canada flights from Detroit to South America

Our best Air Canada deals on Detroit to South America flight tickets
Air Canada
May 9
DTW10:15 amDetroit Metropolitan Wayne County
18h 50m
1 stop
BOG4:05 amBogotá El Dorado
May 16
BOG9:00 amBogotá El Dorado
11h 25m
1 stop
DTW9:25 pmDetroit Metropolitan Wayne County
$563
Air Canada
May 9
DTW2:55 pmDetroit Metropolitan Wayne County
14h 10m
2 stops
BOG4:05 amBogotá El Dorado
May 16
BOG9:00 amBogotá El Dorado
11h 25m
1 stop
DTW9:25 pmDetroit Metropolitan Wayne County
$578
Air Canada
May 14
DTW10:15 amDetroit Metropolitan Wayne County
18h 50m
1 stop
BOG4:05 amBogotá El Dorado
May 23
BOG9:00 amBogotá El Dorado
11h 25m
1 stop
DTW9:25 pmDetroit Metropolitan Wayne County
$595

Spirit Airlines flights from Detroit to South America

Our best Spirit Airlines deals on Detroit to South America flight tickets
Spirit Airlines
Jun 10
DTW6:00 amDetroit Metropolitan Wayne County
7h 26m
1 stop
CTG12:26 pmCartagena Rafael Nunez
Jun 17
CTG1:31 pmCartagena Rafael Nunez
9h 22m
1 stop
DTW11:53 pmDetroit Metropolitan Wayne County
$394
Spirit Airlines
May 27
DTW6:00 amDetroit Metropolitan Wayne County
7h 26m
1 stop
CTG12:26 pmCartagena Rafael Nunez
Jun 4
CTG1:31 pmCartagena Rafael Nunez
9h 22m
1 stop
DTW11:53 pmDetroit Metropolitan Wayne County
$395
Spirit Airlines
Jul 4
DTW8:29 pmDetroit Metropolitan Wayne County
16h 38m
1 stop
CTG12:07 pmCartagena Rafael Nunez
Jul 13
CTG1:12 pmCartagena Rafael Nunez
9h 38m
1 stop
DTW11:50 pmDetroit Metropolitan Wayne County
$419

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Detroit to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Wed 5/27

6:05 pm-12:26 pm

2 stops19h 21m

Cartagena Rafael Nunez

Wed 6/3

1:31 pm-11:53 pm

1 stop9h 22m

$392
Quickest round-trip

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Wed 6/10

6:00 am-12:26 pm

1 stop7h 26m

Cartagena Rafael Nunez

Wed 6/17

1:31 pm-11:53 pm

1 stop9h 22m

$394

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Wed 5/27

6:00 am-12:26 pm

1 stop7h 26m

Cartagena Rafael Nunez

Thu 6/4

1:31 pm-11:53 pm

1 stop9h 22m

$395

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Sat 5/9

10:15 am-4:05 am

1 stop18h 50m

Bogotá El Dorado

Sat 5/16

9:00 am-9:25 pm

1 stop11h 25m

$563

DetroitBuenos Aires

DTW - EZE

DTWEZE

Detroit Metropolitan Wayne County

Fri 9/11

10:05 am-2:30 pm

2 stops27h 25m

Buenos Aires Ministro Pistarini

Mon 9/21

4:35 pm-9:29 pm

2 stops29h 54m

$971

DetroitCusco

DTW - CUZ

DTWCUZ

Detroit Metropolitan Wayne County

Mon 10/5

7:45 pm-10:00 am

2 stops15h 15m

Cusco Velazco Astete

Mon 10/12

6:10 pm-3:11 pm

2 stops20h 01m

$1,013

DetroitCusco

DTW - CUZ

DTWCUZ

Detroit Metropolitan Wayne County

Thu 10/15

6:30 pm-1:35 pm

2 stops20h 05m

Cusco Velazco Astete

Sun 10/25

6:10 pm-3:11 pm

2 stops20h 01m

$1,053

DetroitCusco

DTW - CUZ

DTWCUZ

Detroit Metropolitan Wayne County

Sat 8/15

8:25 am-1:00 am

2 stops17h 35m

Cusco Velazco Astete

Mon 8/24

8:35 am-3:11 pm

2 stops29h 36m

$1,069

DetroitCusco

DTW - CUZ

DTWCUZ

Detroit Metropolitan Wayne County

Mon 8/3

6:00 am-7:20 am

2 stops26h 20m

Cusco Velazco Astete

Thu 8/13

8:05 pm-3:55 pm

2 stops18h 50m

$1,070

DetroitCusco

DTW - CUZ

DTWCUZ

Detroit Metropolitan Wayne County

Mon 8/3

6:00 am-7:20 am

2 stops26h 20m

Cusco Velazco Astete

Thu 8/13

8:05 pm-3:55 pm

2 stops18h 50m

$1,108

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $105. If you aren’t able to travel during the month of October, then book flights to South America from Detroit during March instead. Flights to South America in March, while not as cheap as those in October, still average around $119.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $837 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $512 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 33% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Fastest flight time

7h 07m

Direct flights

None
The fastest flight from Detroit to South America takes 7h 07m
There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Frequently asked questions about flying from Detroit to South America

  • When did momondo last update prices for flights from Detroit to South America?

    Prices for flights from Detroit to South America refresh daily.

  • How many operators does momondo search for flights from Detroit to South America?

  • How old do you have to be to fly from Detroit to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $271Free CancellationRating
6.3
8,632 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $452Free CancellationRating
7.1
11,678 reviews
Search American Airlines flights
DeltaPriceFrom $563Free CancellationRating
7.9
8,465 reviews
Search Delta flights
Copa AirlinesPriceFrom $650Free CancellationRating
7.5
1,580 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $730Free CancellationRating
7.4
1,912 reviews
Search LATAM Airlines flights
Air CanadaPriceFrom $773Free CancellationRating
7.1
10,979 reviews
Search Air Canada flights
United AirlinesPriceFrom $1,078Free CancellationRating
7.4
9,679 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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1 adult
Fri 5/29
Fri 6/5

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