What is the cheapest airline that flies from Detroit to South America?

American Airlines, United Airlines, and JetBlue are the most popular carriers operating from Detroit to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of September 2026, there are 8 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$231 Cheap Flights from Detroit to South America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to South America

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:37 pm - 9:41 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 04m1 stop Fort Lauderdale

$438JetBlue

Tue, Oct 20 - Thu, Oct 22

5:03 pm - 1:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

20h 32m2 stops Washington, D.C. Reagan-National Miami

4:38 pm - 11:32 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

18h 54m2 stops Miami Dallas/Fort Worth

$443American Airlines

Fri, Jan 29 - Sat, Feb 6

7:22 pm - 12:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

18h 13m2 stops Philadelphia Miami

1:35 pm - 2:47 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

24h 12m2 stops Miami Philadelphia

$443American Airlines

Sat, Oct 24 - Wed, Oct 28

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

12:37 pm - 9:41 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 04m1 stop Fort Lauderdale

$494JetBlue

Tue, Oct 20 - Wed, Oct 21

7:26 am - 10:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

38h 44m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:40 am - 10:27 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 47m1 stop Houston George Bush Intcntl

$528United Airlines

Thu, Nov 5 - Wed, Nov 11

7:26 am - 10:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

38h 44m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:40 am - 10:27 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 47m1 stop Houston George Bush Intcntl

$528United Airlines

Fri, Nov 6 - Fri, Nov 13

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

9:30 pm - 10:02 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

23h 32m2 stops Bogotá El Dorado Miami

$530Multiple Airlines

Tue, Oct 20 - Wed, Oct 21

6:00 am - 11:34 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

17h 34m2 stops Charlotte Douglas Miami

3:12 pm - 9:01 amMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

17h 49m2 stops Miami Washington, D.C. Reagan-National

$541GOL

Thu, Nov 5 - Wed, Nov 11

6:00 am - 11:37 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 37m1 stop Fort Lauderdale

2:30 pm - 9:27 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

17h 57m1 stop Atlanta Hartsfield-Jackson

$563Multiple Airlines

Wed, Oct 21 - Sat, Oct 24

6:56 pm - 7:10 amDTW Detroit Metropolitan Wayne County-GRU Sao Paulo Guarulhos Intl

34h 14m2 stops Miami Belém Val De Cans

6:00 pm - 11:43 pmGRU Sao Paulo Guarulhos Intl-DTW Detroit Metropolitan Wayne County

31h 43m2 stops Fortaleza Pinto Martins Miami

$941GOL

Sat, Dec 12 - Sat, Jan 16

Cheap last minute flights

Enter your travel dates to find the best prices.

7:55 pm - 1:55 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

19h 00m1 stop Boston Logan Intl

11:55 pm - 2:15 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

13h 20m1 stop Boston Logan Intl

$590Multiple Airlines

Fri, Oct 2 - Mon, Oct 12

7:55 pm - 1:55 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

19h 00m1 stop Boston Logan Intl

11:55 pm - 2:15 pmBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

13h 20m1 stop Boston Logan Intl

$630Multiple Airlines

Fri, Oct 2 - Mon, Oct 12

5:30 am - 9:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

40h 40m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

9:45 am - 6:05 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

31h 20m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$682United Airlines

Wed, Sep 30 - Wed, Oct 7

6:15 am - 9:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 55m1 stop Houston George Bush Intcntl

9:45 am - 10:30 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 45m1 stop Houston George Bush Intcntl

$690United Airlines

Tue, Sep 29 - Thu, Oct 1

6:00 am - 8:15 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 15m1 stop Miami

6:00 am - 10:57 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

15h 57m1 stop Miami

$719American Airlines

Sun, Sep 27 - Tue, Sep 29

7:59 pm - 12:48 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

17h 49m2 stops Charlotte Douglas Miami

1:53 pm - 9:47 amMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

18h 54m2 stops Miami Chicago O'Hare Intl

$724American Airlines

Sun, Sep 27 - Tue, Sep 29

8:25 am - 7:15 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

11h 50m1 stop Atlanta Hartsfield-Jackson

2:55 pm - 12:58 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

9h 03m1 stop Atlanta Hartsfield-Jackson

$1,126Delta

Thu, Oct 1 - Thu, Oct 8

10:30 am - 7:15 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

9h 45m1 stop Atlanta Hartsfield-Jackson

2:55 pm - 12:52 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

8h 57m1 stop Atlanta Hartsfield-Jackson

$1,151Delta

Thu, Oct 1 - Sat, Oct 10

2:00 pm - 2:30 pmDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

47h 30m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Sao Paulo Guarulhos Intl

4:35 pm - 9:29 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

53h 54m3 stops Sao Paulo Guarulhos Intl Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

$1,402Air Canada

Mon, Sep 28 - Wed, Sep 30

2:00 pm - 2:30 pmDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

47h 30m3 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl Sao Paulo Guarulhos Intl

4:35 pm - 9:29 pmEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

29h 54m2 stops Sao Paulo Guarulhos Intl Montreal Pierre Elliott Trudeau Intl

$1,448Air Canada

Mon, Sep 28 - Wed, Sep 30

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Frontier flights from Detroit to South America

Our best Frontier deals on Detroit to South America flight tickets

Frontier

Jan 20

DTW8:17 pmDetroit Metropolitan Wayne County

14h 48m

1 stop

BOG11:05 amBogotá El Dorado

Jan 27

BOG3:20 pmBogotá El Dorado

9h 47m

1 stop

DTW1:07 amDetroit Metropolitan Wayne County

$564

Frontier

Feb 25

DTW8:17 pmDetroit Metropolitan Wayne County

15h 43m

1 stop

MDE12:00 pmMedellín Jose Maria Cordova Intl

Mar 2

MDE1:10 pmMedellín Jose Maria Cordova Intl

11h 57m

1 stop

DTW1:07 amDetroit Metropolitan Wayne County

$579

Frontier

Dec 10

DTW1:32 pmDetroit Metropolitan Wayne County

46h 28m

2 stops

MDE12:00 pmMedellín Jose Maria Cordova Intl

Dec 20

MDE1:10 pmMedellín Jose Maria Cordova Intl

11h 31m

1 stop

DTW12:41 amDetroit Metropolitan Wayne County

$588

Avianca flights from Detroit to South America

Our best Avianca deals on Detroit to South America flight tickets

Avianca

Sep 29

DTW7:48 pmDetroit Metropolitan Wayne County

16h 27m

1 stop

BOG11:15 amBogotá El Dorado

Oct 10

BOG10:50 pmBogotá El Dorado

10h 10m

1 stop

DTW10:00 amDetroit Metropolitan Wayne County

$906

Avianca

Oct 4

DTW6:00 amDetroit Metropolitan Wayne County

30h 15m

1 stop

BOG11:15 amBogotá El Dorado

Oct 7

BOG10:50 pmBogotá El Dorado

10h 10m

1 stop

DTW10:00 amDetroit Metropolitan Wayne County

$916

Avianca

Oct 3

DTW7:48 pmDetroit Metropolitan Wayne County

21h 12m

2 stops

BOG4:00 pmBogotá El Dorado

Oct 10

BOG10:50 pmBogotá El Dorado

10h 10m

1 stop

DTW10:00 amDetroit Metropolitan Wayne County

$920

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/20

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Thu 10/22

12:37 pm-9:41 pm

1 stop8h 04m

$438

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Fri 1/29

5:03 pm-1:35 pm

2 stops20h 32m

Cartagena Rafael Nunez

Sat 2/6

4:38 pm-11:32 am

2 stops18h 54m

$443

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Sat 10/24

7:22 pm-12:35 pm

2 stops18h 13m

Cartagena Rafael Nunez

Wed 10/28

1:35 pm-2:47 pm

2 stops24h 12m

$443

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/20

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Wed 10/21

12:37 pm-9:41 pm

1 stop8h 04m

$494

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Thu 11/5

7:26 am-10:10 pm

2 stops38h 44m

Medellín Jose Maria Cordova Intl

Wed 11/11

10:40 am-10:27 pm

1 stop11h 47m

$528

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Fri 11/6

7:26 am-10:10 pm

2 stops38h 44m

Medellín Jose Maria Cordova Intl

Fri 11/13

10:40 am-10:27 pm

1 stop11h 47m

$528

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Tue 10/20

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Wed 10/21

9:30 pm-10:02 pm

2 stops23h 32m

$530

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Thu 11/5

6:00 am-11:34 pm

2 stops17h 34m

Medellín Jose Maria Cordova Intl

Wed 11/11

3:12 pm-9:01 am

2 stops17h 49m

$541

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Wed 10/21

6:00 am-11:37 am

1 stop6h 37m

Cartagena Rafael Nunez

Sat 10/24

2:30 pm-9:27 am

1 stop17h 57m

$563

DetroitSao Paulo

DTW Detroit Metropolitan Wayne County - GRU Sao Paulo Guarulhos Intl

DTWGRU

Detroit Metropolitan Wayne County

Sat 12/12

6:56 pm-7:10 am

2 stops34h 14m

Sao Paulo Guarulhos Intl

Sat 1/16

6:00 pm-11:43 pm

2 stops31h 43m

$941

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $621. If you aren’t able to travel during the month of February, then book flights to South America from Detroit during January instead. Flights to South America in January, while not as cheap as those in February, still average around $633.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $833 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $602 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 49% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Best Price Found	$231
Fastest flight time	6h 37m
Direct flights	None

The best one-way flight to South America from Detroit in the past 72 hours is $231. The best round-trip flight deal from Detroit to South America found on momondo in the last 72 hours is $438.

The fastest flight from Detroit to South America takes 6h 37m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

Frequently asked questions about flying from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of September 2026, there are 8 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $217	Free Cancellation	Rating 7.8 8,609 reviews	Search Delta flights
American Airlines	PriceFrom $295	Free Cancellation	Rating 7.0 12,098 reviews	Search American Airlines flights
JetBlue	PriceFrom $421	Free Cancellation	Rating 7.1 3,041 reviews	Search JetBlue flights
Copa Airlines	PriceFrom $614	Free Cancellation	Rating 7.6 1,544 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $676	Free Cancellation	Rating 7.4 1,980 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $676	Free Cancellation	Rating 7.1 11,696 reviews	Search Air Canada flights
GOL	PriceFrom $981	Free Cancellation	Rating 7.3 1,314 reviews	Search GOL flights
United Airlines	PriceFrom $1,133	Free Cancellation	Rating 7.4 10,243 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.