What airlines fly to South America?

Spirit Airlines, Delta and American Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Spirit Airlines is the first choice among our users, with 30% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Detroit to South America?

Spirit Airlines is the most popular carrier operating from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of November 2025, there are 7 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$101 Cheap Flights from Detroit to South America in 2025/26

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Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:50 pm - 1:10 pmDTW-CTG

22h 20m2 stops

2:15 pm - 12:19 amCTG-DTW

10h 04m1 stop

$288Spirit Airlines

Find Deal

Sat, Dec 6 - Mon, Dec 15

2:50 pm - 1:10 pmDTW-CTG

22h 20m2 stops

2:15 pm - 8:07 amCTG-DTW

17h 52m2 stops

$291Spirit Airlines

Find Deal

Sat, Dec 6 - Mon, Dec 15

2:50 pm - 1:10 pmDTW-CTG

22h 20m2 stops

2:15 pm - 12:19 amCTG-DTW

10h 04m1 stop

$298Spirit Airlines

Find Deal

Sat, Dec 6 - Mon, Dec 15

6:58 pm - 1:09 amDTW-MDE

30h 11m1 stop

2:05 am - 10:08 amMDE-DTW

8h 03m1 stop

$299Spirit Airlines

Find Deal

Sat, Dec 6 - Fri, Dec 12

2:50 pm - 1:10 pmDTW-CTG

22h 20m2 stops

2:15 pm - 12:19 amCTG-DTW

10h 04m1 stop

$303Spirit Airlines

Find Deal

Sat, Dec 6 - Sat, Dec 13

5:15 am - 12:50 pmDTW-BOG

7h 35m1 stop

1:47 pm - 11:41 pmBOG-DTW

9h 54m1 stop

$308Spirit Airlines

Find Deal

Sun, Feb 1 - Sat, Feb 28

6:01 pm - 12:50 pmDTW-BOG

18h 49m1 stop

1:47 pm - 11:41 pmBOG-DTW

9h 54m1 stop

$310Spirit Airlines

Find Deal

Sun, Feb 1 - Sat, Feb 28

4:48 pm - 1:13 pmDTW-CTG

20h 25m1 stop

2:21 pm - 11:40 amCTG-DTW

21h 19m2 stops

$312Multiple Airlines

Find Deal

Sat, Feb 21 - Wed, Feb 25

5:30 am - 9:35 pmDTW-CGH

38h 05m2 stops

6:30 am - 10:45 pmCGH-DTW

17h 15m2 stops

$773GOL

Find Deal

Mon, Feb 9 - Tue, Apr 7

11:29 am - 9:40 pmDTW-CGH

32h 11m2 stops

8:20 pm - 11:30 amCGH-DTW

41h 10m2 stops

$810GOL

Find Deal

Sat, Jan 24 - Fri, Jan 30

American Airlines flights from Detroit to South America

Our best American Airlines deals on Detroit to South America flight tickets

American Airlines

May 5

DTW5:56 pmDetroit Metropolitan Wayne County

13h 09m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

May 12

SCL8:50 pmSantiago Arturo Merino Benitez

20h 29m

1 stop

DTW5:19 pmDetroit Metropolitan Wayne County

$904

Find similar

American Airlines

May 5

DTW2:54 pmDetroit Metropolitan Wayne County

16h 11m

2 stops

SCL7:05 amSantiago Arturo Merino Benitez

May 12

SCL8:50 pmSantiago Arturo Merino Benitez

15h 30m

2 stops

DTW12:20 pmDetroit Metropolitan Wayne County

$909

Find similar

American Airlines

Nov 25

DTW6:00 amDetroit Metropolitan Wayne County

15h 30m

1 stop

LIM9:30 pmLima J Chavez Intl

Nov 28

LIM7:00 amLima J Chavez Intl

16h 51m

1 stop

DTW11:51 pmDetroit Metropolitan Wayne County

$1,002

Find similar

Spirit Airlines flights from Detroit to South America

Our best Spirit Airlines deals on Detroit to South America flight tickets

Spirit Airlines

Dec 6

DTW2:50 pmDetroit Metropolitan Wayne County

22h 20m

2 stops

CTG1:10 pmCartagena Rafael Nunez

Dec 15

CTG2:15 pmCartagena Rafael Nunez

10h 04m

1 stop

DTW12:19 amDetroit Metropolitan Wayne County

$288

Find similar

Spirit Airlines

Dec 6

DTW2:50 pmDetroit Metropolitan Wayne County

22h 20m

2 stops

CTG1:10 pmCartagena Rafael Nunez

Dec 15

CTG2:15 pmCartagena Rafael Nunez

17h 52m

2 stops

DTW8:07 amDetroit Metropolitan Wayne County

$291

Find similar

Spirit Airlines

Dec 6

DTW2:50 pmDetroit Metropolitan Wayne County

22h 20m

2 stops

CTG1:10 pmCartagena Rafael Nunez

Dec 15

CTG2:15 pmCartagena Rafael Nunez

10h 04m

1 stop

DTW12:19 amDetroit Metropolitan Wayne County

$298

Find similar

Fly from

Fly to

Route

Depart

Return

Price

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 12/6

2:50 pm-1:10 pm

2 stops22h 20m

Cartagena Rafael Nunez

Mon 12/15

2:15 pm-12:19 am

1 stop10h 04m

$288

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 12/6

2:50 pm-1:10 pm

2 stops22h 20m

Cartagena Rafael Nunez

Mon 12/15

2:15 pm-8:07 am

2 stops17h 52m

$291

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 12/6

2:50 pm-1:10 pm

2 stops22h 20m

Cartagena Rafael Nunez

Mon 12/15

2:15 pm-12:19 am

1 stop10h 04m

$298

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Sat 12/6

6:58 pm-1:09 am

1 stop30h 11m

Medellín Jose Maria Cordova Intl

Fri 12/12

2:05 am-10:08 am

1 stop8h 03m

$299

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 12/6

2:50 pm-1:10 pm

2 stops22h 20m

Cartagena Rafael Nunez

Sat 12/13

2:15 pm-12:19 am

1 stop10h 04m

$303

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Sun 2/1

5:15 am-12:50 pm

1 stop7h 35m

Bogotá El Dorado

Sat 2/28

1:47 pm-11:41 pm

1 stop9h 54m

$308

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Sun 2/1

6:01 pm-12:50 pm

1 stop18h 49m

Bogotá El Dorado

Sat 2/28

1:47 pm-11:41 pm

1 stop9h 54m

$310

DetroitCartagena

DTW - CTG

DTWCTG

Detroit Metropolitan Wayne County

Sat 2/21

4:48 pm-1:13 pm

1 stop20h 25m

Cartagena Rafael Nunez

Wed 2/25

2:21 pm-11:40 am

2 stops21h 19m

$312

DetroitSao Paulo

DTW - CGH

DTWCGH

Detroit Metropolitan Wayne County

Mon 2/9

5:30 am-9:35 pm

2 stops38h 05m

Sao Paulo Congonhas

Tue 4/7

6:30 am-10:45 pm

2 stops17h 15m

$773

DetroitSao Paulo

DTW - CGH

DTWCGH

Detroit Metropolitan Wayne County

Sat 1/24

11:29 am-9:40 pm

2 stops32h 11m

Sao Paulo Congonhas

Fri 1/30

8:20 pm-11:30 am

2 stops41h 10m

$810

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $524. If you aren’t able to travel during the month of September, then book flights to South America from Detroit during August instead. Flights to South America in August, while not as cheap as those in September, still average around $622.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Detroit to South America is on a Tuesday when prices can be found for as low as $793. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Detroit to South America for around $999.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Detroit to South America flights are usually those with departure times in the morning. Our users have found flights to South America in the morning for as low as $923. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $954 on average. Flights to South America from Detroit in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $971 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $658 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 10% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Direct flights	None

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of November 2025, there are 7 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $104	Free Cancellation	Rating 6.3 8,139 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $417	Free Cancellation	Rating 7.2 11,050 reviews	Search American Airlines flights
Delta	PriceFrom $527	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
United Airlines	PriceFrom $550	Free Cancellation	Rating 7.4 9,017 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $583	Free Cancellation	Rating 7.6 1,565 reviews	Search Copa Airlines flights
Air Canada	PriceFrom $585	Free Cancellation	Rating 7.1 10,444 reviews	Search Air Canada flights
LATAM Airlines	PriceFrom $652	Free Cancellation	Rating 7.5 1,875 reviews	Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.