What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Detroit according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Detroit to South America?

JetBlue, American Airlines, and United Airlines are the most popular carriers operating from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?

Prices for flights from Detroit to South America refresh daily.

How many operators does momondo search for flights from Detroit to South America?

As of August 2026, there are 7 operators available to choose from for flights from Detroit to South America.

How old do you have to be to fly from Detroit to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$192 Cheap Flights from Detroit to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:03 pm - 12:35 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

16h 32m2 stops Chicago O'Hare Intl Miami

1:35 pm - 9:47 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

19h 12m2 stops Miami Chicago O'Hare Intl

$431American Airlines

Mon, Sep 7 - Wed, Sep 16

6:00 am - 2:15 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

9h 15m1 stop Miami

1:35 pm - 8:44 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

18h 09m2 stops Miami New York LaGuardia

$431American Airlines

Mon, Sep 7 - Wed, Sep 16

6:00 am - 12:43 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 43m1 stop Fort Lauderdale

1:49 pm - 9:47 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

7h 58m1 stop Fort Lauderdale

$437JetBlue

Mon, Nov 30 - Wed, Dec 9

6:00 am - 11:30 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 30m1 stop Fort Lauderdale

12:35 pm - 9:45 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 10m1 stop Fort Lauderdale

$437JetBlue

Mon, Oct 19 - Thu, Oct 22

6:15 am - 9:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 55m1 stop Houston George Bush Intcntl

9:45 am - 10:30 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 45m1 stop Houston George Bush Intcntl

$467United Airlines

Tue, Oct 20 - Fri, Oct 23

6:15 am - 9:10 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

15h 55m1 stop Houston George Bush Intcntl

9:45 am - 10:27 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

11h 42m1 stop Houston George Bush Intcntl

$467United Airlines

Fri, Oct 23 - Thu, Oct 29

6:00 am - 12:43 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 43m1 stop Fort Lauderdale

3:25 pm - 9:27 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

18h 02m1 stop Atlanta Hartsfield-Jackson

$489Multiple Airlines

Mon, Nov 30 - Sat, Dec 12

6:00 am - 12:43 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 43m1 stop Fort Lauderdale

3:25 pm - 12:57 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

9h 32m1 stop Atlanta Hartsfield-Jackson

$515Multiple Airlines

Mon, Nov 30 - Mon, Dec 14

3:59 pm - 3:51 pmDTW Detroit Metropolitan Wayne County-UIO Quito Mariscal Sucr

23h 52m2 stops New York John F Kennedy Intl Guayaquil Jose Joaquin de Olmedo

7:05 am - 10:20 pmUIO Quito Mariscal Sucr-DTW Detroit Metropolitan Wayne County

15h 15m2 stops Bogotá El Dorado Miami

$711LATAM Airlines

Mon, Nov 16 - Thu, Nov 19

8:04 pm - 3:51 pmDTW Detroit Metropolitan Wayne County-UIO Quito Mariscal Sucr

19h 47m2 stops New York John F Kennedy Intl Guayaquil Jose Joaquin de Olmedo

8:55 am - 10:20 pmUIO Quito Mariscal Sucr-DTW Detroit Metropolitan Wayne County

13h 25m1 stop Miami

$711LATAM Airlines

Mon, Nov 16 - Thu, Nov 19

Cheap last minute flights

Enter your travel dates to find the best prices.

7:54 pm - 12:48 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

17h 54m2 stops Charlotte Douglas Miami

1:50 pm - 4:36 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

25h 46m2 stops Miami Washington, D.C. Reagan-National

$510GOL

Sun, Aug 23 - Tue, Aug 25

6:00 am - 12:48 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

7h 48m1 stop Miami

1:50 pm - 4:36 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

25h 46m2 stops Miami Washington, D.C. Reagan-National

$510GOL

Sun, Aug 23 - Tue, Aug 25

6:00 am - 12:48 pmDTW Detroit Metropolitan Wayne County-MDE Medellín Jose Maria Cordova Intl

7h 48m1 stop Miami

6:00 am - 10:59 pmMDE Medellín Jose Maria Cordova Intl-DTW Detroit Metropolitan Wayne County

15h 59m1 stop Miami

$658American Airlines

Sun, Aug 23 - Tue, Aug 25

6:00 am - 11:35 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 35m1 stop Fort Lauderdale

12:35 pm - 9:45 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 10m1 stop Fort Lauderdale

$824JetBlue

Mon, Aug 24 - Sun, Aug 30

6:00 am - 2:15 pmDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

9h 15m2 stops Washington, D.C. Reagan-National Miami

1:35 pm - 10:52 amCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

20h 17m2 stops Miami Dallas/Fort Worth

$829American Airlines

Mon, Aug 24 - Sun, Aug 30

7:48 pm - 12:00 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

17h 12m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

2:45 pm - 10:10 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

18h 25m2 stops Guatemala City La Aurora Washington, D.C. Dulles Intl

$840Avianca

Mon, Aug 24 - Mon, Aug 31

7:48 pm - 12:30 pmDTW Detroit Metropolitan Wayne County-BOG Bogotá El Dorado

17h 42m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl

2:45 pm - 10:10 amBOG Bogotá El Dorado-DTW Detroit Metropolitan Wayne County

18h 25m2 stops Guatemala City La Aurora Washington, D.C. Dulles Intl

$846Avianca

Mon, Aug 24 - Mon, Aug 31

6:00 am - 11:35 amDTW Detroit Metropolitan Wayne County-CTG Cartagena Rafael Nunez

6h 35m1 stop Fort Lauderdale

12:35 pm - 9:45 pmCTG Cartagena Rafael Nunez-DTW Detroit Metropolitan Wayne County

8h 10m1 stop Fort Lauderdale

$894JetBlue

Mon, Aug 24 - Sun, Aug 30

9:09 am - 9:40 amDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

23h 31m1 stop Miami

8:10 pm - 11:15 amEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

16h 05m1 stop Atlanta Hartsfield-Jackson

$2,130LATAM Airlines

Mon, Aug 24 - Wed, Aug 26

2:59 pm - 9:45 amDTW Detroit Metropolitan Wayne County-EZE Buenos Aires Ministro Pistarini

17h 46m1 stop Atlanta Hartsfield-Jackson

8:10 pm - 11:15 amEZE Buenos Aires Ministro Pistarini-DTW Detroit Metropolitan Wayne County

16h 05m1 stop Atlanta Hartsfield-Jackson

$2,175LATAM Airlines

Sun, Aug 23 - Tue, Aug 25

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Air Canada flights from Detroit to South America

Our best Air Canada deals on Detroit to South America flight tickets

Air Canada

Nov 19

DTW6:20 pmDetroit Metropolitan Wayne County

11h 50m

1 stop

LIM6:10 amLima J Chavez Intl

Nov 30

LIM8:00 amLima J Chavez Intl

33h 40m

2 stops

DTW5:40 pmDetroit Metropolitan Wayne County

$650

Air Canada

Nov 19

DTW6:20 pmDetroit Metropolitan Wayne County

32h 55m

2 stops

LIM3:15 amLima J Chavez Intl

Nov 30

LIM8:00 amLima J Chavez Intl

33h 40m

2 stops

DTW5:40 pmDetroit Metropolitan Wayne County

$654

Air Canada

Sep 1

DTW10:15 amDetroit Metropolitan Wayne County

18h 50m

1 stop

BOG4:05 amBogotá El Dorado

Sep 15

BOG9:00 amBogotá El Dorado

28h 12m

2 stops

DTW2:12 pmDetroit Metropolitan Wayne County

$820

Avianca flights from Detroit to South America

Our best Avianca deals on Detroit to South America flight tickets

Avianca

Aug 24

DTW7:48 pmDetroit Metropolitan Wayne County

17h 12m

2 stops

BOG12:00 pmBogotá El Dorado

Aug 31

BOG2:45 pmBogotá El Dorado

18h 25m

2 stops

DTW10:10 amDetroit Metropolitan Wayne County

$840

Avianca

Aug 24

DTW7:48 pmDetroit Metropolitan Wayne County

17h 42m

3 stops

BOG12:30 pmBogotá El Dorado

Aug 31

BOG2:45 pmBogotá El Dorado

18h 25m

2 stops

DTW10:10 amDetroit Metropolitan Wayne County

$846

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 9/7

9:03 pm-12:35 pm

2 stops16h 32m

Cartagena Rafael Nunez

Wed 9/16

1:35 pm-9:47 am

2 stops19h 12m

$431

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 9/7

6:00 am-2:15 pm

1 stop9h 15m

Cartagena Rafael Nunez

Wed 9/16

1:35 pm-8:44 am

2 stops18h 09m

$431

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 11/30

6:00 am-12:43 pm

1 stop6h 43m

Cartagena Rafael Nunez

Wed 12/9

1:49 pm-9:47 pm

1 stop7h 58m

$437

Quickest round-trip

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 10/19

6:00 am-11:30 am

1 stop6h 30m

Cartagena Rafael Nunez

Thu 10/22

12:35 pm-9:45 pm

1 stop8h 10m

$437

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Tue 10/20

6:15 am-9:10 pm

1 stop15h 55m

Medellín Jose Maria Cordova Intl

Fri 10/23

9:45 am-10:30 pm

1 stop11h 45m

$467

DetroitMedellín

DTW Detroit Metropolitan Wayne County - MDE Medellín Jose Maria Cordova Intl

DTWMDE

Detroit Metropolitan Wayne County

Fri 10/23

6:15 am-9:10 pm

1 stop15h 55m

Medellín Jose Maria Cordova Intl

Thu 10/29

9:45 am-10:27 pm

1 stop11h 42m

$467

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 11/30

6:00 am-12:43 pm

1 stop6h 43m

Cartagena Rafael Nunez

Sat 12/12

3:25 pm-9:27 am

1 stop18h 02m

$489

DetroitCartagena

DTW Detroit Metropolitan Wayne County - CTG Cartagena Rafael Nunez

DTWCTG

Detroit Metropolitan Wayne County

Mon 11/30

6:00 am-12:43 pm

1 stop6h 43m

Cartagena Rafael Nunez

Mon 12/14

3:25 pm-12:57 am

1 stop9h 32m

$515

DetroitQuito

DTW Detroit Metropolitan Wayne County - UIO Quito Mariscal Sucr

DTWUIO

Detroit Metropolitan Wayne County

Mon 11/16

3:59 pm-3:51 pm

2 stops23h 52m

Quito Mariscal Sucr

Thu 11/19

7:05 am-10:20 pm

2 stops15h 15m

$711

DetroitQuito

DTW Detroit Metropolitan Wayne County - UIO Quito Mariscal Sucr

DTWUIO

Detroit Metropolitan Wayne County

Mon 11/16

8:04 pm-3:51 pm

2 stops19h 47m

Quito Mariscal Sucr

Thu 11/19

8:55 am-10:20 pm

1 stop13h 25m

$711

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Detroit to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $616. If you aren’t able to travel during the month of February, then book flights to South America from Detroit during January instead. Flights to South America in January, while not as cheap as those in February, still average around $633.

How far in advance should I book a flight from Detroit to South America?

You are more likely to see cheaper flights to South America from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $858 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Detroit for as low as $619 on momondo.

Can stopping save me money on Detroit to South America flights?

You could potentially save up to 49% on your flight if you consider stops on a Detroit to South America flight.

Cheap Detroit to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to South America

Best Price Found	$192
Fastest flight time	6h 30m
Direct flights	None

The best one-way flight to South America from Detroit in the past 72 hours is $192. The best round-trip flight deal from Detroit to South America found on momondo in the last 72 hours is $431.

The fastest flight from Detroit to South America takes 6h 30m

There are no direct flights from Detroit to South America. There are no popular flight routes from Detroit to South America.

Search flight deals

Frequently asked questions about flying from Detroit to South America

When did momondo last update prices for flights from Detroit to South America?
Prices for flights from Detroit to South America refresh daily.
How many operators does momondo search for flights from Detroit to South America?
As of August 2026, there are 7 operators available to choose from for flights from Detroit to South America.
How old do you have to be to fly from Detroit to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to South America

Compare and see reviews for airlines that fly from Detroit to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $217	Free Cancellation	Rating 7.8 8,513 reviews	Search Delta flights
American Airlines	PriceFrom $295	Free Cancellation	Rating 7.1 11,981 reviews	Search American Airlines flights
JetBlue	PriceFrom $326	Free Cancellation	Rating 7.1 3,041 reviews	Search JetBlue flights
LATAM Airlines	PriceFrom $676	Free Cancellation	Rating 7.4 1,989 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $676	Free Cancellation	Rating 7.1 11,513 reviews	Search Air Canada flights
GOL	PriceFrom $981	Free Cancellation	Rating 7.3 1,281 reviews	Search GOL flights
United Airlines	PriceFrom $1,119	Free Cancellation	Rating 7.4 10,107 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Detroit.

Can I find flights from Detroit to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to South America?

momondo helps you find the best flight between Detroit and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.