Cheap flights from Detroit to Myrtle Beach from $121

In general, January is the cheapest month to fly from Detroit to Myrtle Beach. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $320. If you are unable to visit Myrtle Beach during the month of January, then departing from Detroit during the month November is also very affordable. Most momondo users find prices during this month for around $349.

Our data shows that Saturday is the least expensive day to fly to Myrtle Beach. Tickets to fly out on this day can be as low as $389. The most expensive day to fly to Myrtle Beach is Sunday, with ticket prices averaging around $459.

The cheapest time of day to fly to Myrtle Beach is in the evening when flights can be purchased for as low as $113. Flights in the morning are often more expensive with an average ticket price of $421.

Fly from Detroit Metropolitan Wayne County to Myrtle Beach Intl for the best Detroit - Myrtle Beach Intl flight prices

You are more likely to see cheaper flights to Myrtle Beach from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Myrtle Beach for around $379 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Myrtle Beach from Detroit for as low as $244 on momondo.

There are 4 cabin classes available to choose from on Detroit to Myrtle Beach flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 42% on your flight if you consider stops on a Detroit to Myrtle Beach flight.

Southwest is the most popular carrier operating from Detroit to Myrtle Beach Intl

Delta, American Airlines and Southwest are the top three most popular airlines that fly to Myrtle Beach from Detroit according to our data. Delta is the first choice among our users, with 70% of people opting to fly with this airline when traveling to Myrtle Beach. Keep in mind that there are 4 different airlines that fly to Myrtle Beach on a routine basis, so you have a few additional options to choose from.

As of September 2026, 3 flights take off from Detroit and land in Myrtle Beach each day. The most common flight departure time for this route is 8:00AM, with 100% of daily flights taking off at noon.

The number of flights available between Detroit and Myrtle Beach is 21 per week as of September 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.