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Cheap flights from Detroit to Key West from $225

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Key West departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:54 pm - 10:19 am
DTW
-
EYW
13h 25m
1 stop
Multiple Airlines Logo
10:04 am - 12:42 am
EYW
-
DTW
14h 38m
2 stops
$313Multiple Airlines
Sat, Sep 12 - Wed, Sep 16
Multiple Airlines Logo
7:25 pm - 10:19 am
DTW
-
EYW
14h 54m
1 stop
Multiple Airlines Logo
10:04 am - 12:42 am
EYW
-
DTW
14h 38m
2 stops
$318Multiple Airlines
Sun, Sep 27 - Wed, Sep 30
American Airlines Logo
11:01 am - 5:55 pm
DTW
-
EYW
6h 54m
1 stop
American Airlines Logo
4:39 pm - 9:38 pm
EYW
-
DTW
4h 59m
1 stop
$323American Airlines
Sat, Sep 26 - Tue, Sep 29
Multiple Airlines Logo
6:02 pm - 7:13 pm
DTW
-
EYW
25h 11m
1 stop
Multiple Airlines Logo
11:46 am - 12:40 am
EYW
-
DTW
12h 54m
2 stops
$324Multiple Airlines
Sat, Aug 8 - Wed, Aug 12
American Airlines Logo
3:32 pm - 9:47 pm
DTW
-
EYW
6h 15m
1 stop
American Airlines Logo
2:50 pm - 10:30 pm
EYW
-
DTW
7h 40m
1 stop
$334American Airlines
Sat, Nov 7 - Wed, Nov 11
American Airlines Logo
3:32 pm - 9:47 pm
DTW
-
EYW
6h 15m
1 stop
American Airlines Logo
4:10 pm - 11:56 pm
EYW
-
DTW
7h 46m
1 stop
$338American Airlines
Tue, Dec 1 - Tue, Dec 8
Multiple Airlines Logo
12:27 pm - 11:25 am
DTW
-
EYW
22h 58m
1 stop
Multiple Airlines Logo
11:46 am - 12:40 am
EYW
-
DTW
12h 54m
2 stops
$341Multiple Airlines
Sat, Jul 18 - Wed, Jul 22
Multiple Airlines Logo
2:56 pm - 11:06 am
DTW
-
EYW
20h 10m
2 stops
Multiple Airlines Logo
12:07 pm - 11:55 am
EYW
-
DTW
23h 48m
1 stop
$342Multiple Airlines
Tue, Jul 14 - Mon, Jul 20
American Airlines Logo
1:41 pm - 6:48 pm
DTW
-
EYW
5h 07m
1 stop
American Airlines Logo
7:33 pm - 12:41 am
EYW
-
DTW
5h 08m
1 stop
$345American Airlines
Fri, Jul 17 - Fri, Jul 24
Multiple Airlines Logo
7:25 pm - 10:19 am
DTW
-
EYW
14h 54m
1 stop
Multiple Airlines Logo
10:59 am - 11:17 am
EYW
-
DTW
24h 18m
1 stop
$348Multiple Airlines
Sun, Nov 1 - Thu, Nov 5

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American Airlines flights from Detroit to Key West

Our best American Airlines deals on Detroit to Key West flight tickets
American Airlines
Sep 26
DTW11:01 amDetroit Metropolitan Wayne County
6h 54m
1 stop
EYW5:55 pmKey West
Sep 29
EYW4:39 pmKey West
4h 59m
1 stop
DTW9:38 pmDetroit Metropolitan Wayne County
$323
American Airlines
Nov 7
DTW3:32 pmDetroit Metropolitan Wayne County
6h 15m
1 stop
EYW9:47 pmKey West
Nov 11
EYW2:50 pmKey West
7h 40m
1 stop
DTW10:30 pmDetroit Metropolitan Wayne County
$334
American Airlines
Dec 1
DTW3:32 pmDetroit Metropolitan Wayne County
6h 15m
1 stop
EYW9:47 pmKey West
Dec 8
EYW4:10 pmKey West
7h 46m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$338

United Airlines flights from Detroit to Key West

Our best United Airlines deals on Detroit to Key West flight tickets
United Airlines
Jun 18
DTW6:00 amDetroit Metropolitan Wayne County
9h 09m
2 stops
EYW3:09 pmKey West
Jun 22
EYW2:26 pmKey West
9h 04m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$650
United Airlines
Jun 18
DTW6:00 amDetroit Metropolitan Wayne County
9h 09m
2 stops
EYW3:09 pmKey West
Jun 20
EYW2:26 pmKey West
9h 04m
1 stop
DTW11:30 pmDetroit Metropolitan Wayne County
$680
United Airlines
Jun 18
DTW6:00 amDetroit Metropolitan Wayne County
9h 09m
2 stops
EYW3:09 pmKey West
Jun 22
EYW2:26 pmKey West
9h 25m
2 stops
DTW11:51 pmDetroit Metropolitan Wayne County
$739

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from Detroit to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sat 9/12

8:54 pm-10:19 am

1 stop13h 25m

Key West

Wed 9/16

10:04 am-12:42 am

2 stops14h 38m

$313

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sun 9/27

7:25 pm-10:19 am

1 stop14h 54m

Key West

Wed 9/30

10:04 am-12:42 am

2 stops14h 38m

$318

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sat 9/26

11:01 am-5:55 pm

1 stop6h 54m

Key West

Tue 9/29

4:39 pm-9:38 pm

1 stop4h 59m

$323

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sat 8/8

6:02 pm-7:13 pm

1 stop25h 11m

Key West

Wed 8/12

11:46 am-12:40 am

2 stops12h 54m

$324

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sat 11/7

3:32 pm-9:47 pm

1 stop6h 15m

Key West

Wed 11/11

2:50 pm-10:30 pm

1 stop7h 40m

$334

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Tue 12/1

3:32 pm-9:47 pm

1 stop6h 15m

Key West

Tue 12/8

4:10 pm-11:56 pm

1 stop7h 46m

$338

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sat 7/18

12:27 pm-11:25 am

1 stop22h 58m

Key West

Wed 7/22

11:46 am-12:40 am

2 stops12h 54m

$341

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Tue 7/14

2:56 pm-11:06 am

2 stops20h 10m

Key West

Mon 7/20

12:07 pm-11:55 am

1 stop23h 48m

$342
Quickest round-trip

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Fri 7/17

1:41 pm-6:48 pm

1 stop5h 07m

Key West

Fri 7/24

7:33 pm-12:41 am

1 stop5h 08m

$345

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sun 11/1

7:25 pm-10:19 am

1 stop14h 54m

Key West

Thu 11/5

10:59 am-11:17 am

1 stop24h 18m

$348

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Detroit to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Key West?

What is the cheapest month to fly to Key West?

In general, February is the cheapest month to fly from Detroit to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $130. If you are unable to visit Key West during the month of February, then departing from Detroit during the month November is also very affordable. Most momondo users find prices during this month for around $196.

How far in advance should I book a flight from Detroit to Key West?

You are more likely to see cheaper flights to Key West from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $439 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Detroit for as low as $319 on momondo.

When to book flights from Detroit to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Key West (DTT to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Key West

Fastest flight time

5h 27m

Direct flights

None
The fastest flight from Detroit to Key West takes 5h 27m
There are no direct flights from Detroit to Key West. There are no popular flight routes from Detroit to Key West.
Search flight deals

Frequently asked questions about flying from Detroit to Key West

  • How far is Detroit to Key West by plane?

    A flight from Detroit to Key West will travel around 1229.9 mi. In terms of flight time, this usually takes a little over 5h 27m.

  • When did momondo last update prices for flights from Detroit to Key West Airport?

    Prices for flights from Detroit to Key West Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Detroit to Key West Airport?

  • How old do you have to be to fly from Detroit to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Detroit to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The travel and health documents you'll need for your trip to Key West Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Key West Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Detroit to Key West?

Best airlines flying from Detroit to Key West

Compare and see reviews for airlines that fly from Detroit to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $247Free CancellationRating
7.9
8,405 reviews
Search Delta flights
United AirlinesPriceFrom $268Free CancellationRating
7.4
9,842 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.1
11,665 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Key West?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Detroit to Key West for you.

Can I find flights from Detroit to Key West with flexible booking policies on momondo?

All flight searches from Detroit to Key West on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Key West?

Once you have performed a search for Detroit to Key West flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Detroit to Key West right now. Can momondo alert me if prices change?

Price alerts on flights to Key West from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Key West trip

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