Cheap flights from Detroit to Charleston from $79

The cheapest month to fly to Charleston from Detroit is in September. Flight prices, which tend to average around $198, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Charleston, with average flight prices from Detroit averaging around $229.

The cheapest day to depart from Detroit to Charleston is on a Monday. Travelers who choose to depart for Charleston on a Monday will often find tickets for as low as $299. The most expensive day to fly to Charleston is Thursday, with ticket prices averaging around $342.

The cheapest time of day to fly to Charleston is at noon when flights can be purchased for as low as $299. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $373 per ticket.

Fly from Detroit Metropolitan Wayne County to Charleston for the best Detroit - Charleston flight prices

You are more likely to see cheaper flights to Charleston from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Charleston for around $358 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charleston from Detroit for as low as $185 on momondo.

There are 2 cabin classes available to choose from on Detroit to Charleston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 42% on your flight if you consider stops on a Detroit to Charleston flight.

As of March 2026, prices for Detroit to Charleston flights are approximately 1% cheaper when compared to flights at the same time last year.

JetBlue, Southwest, and Delta are the most popular carriers operating from Detroit to Charleston

Delta, Spirit Airlines and American Airlines are the top three most popular airlines that fly to Charleston from Detroit according to our data. Delta is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Charleston. Keep in mind that there are 4 different airlines that fly to Charleston on a routine basis, so you have a few additional options to choose from.

Newark (EWR) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Charlotte (CLT) offer the lowest average round-trip price of $329.

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 4h 33m.

Charlotte (CLT) has the shortest average layover time for this route: 1h 23m.

The number of flights available between Detroit and Charleston is 4 per day as of March 2026. The most frequent departure time is 3:00PM, with 61% of daily flights leaving in the afternoon.

The number of flights available between Detroit and Charleston is 29 per week as of March 2026. The most frequent departure day is Tue, with 21% of weekly flights leaving on this day.