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Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse from $352

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to La Crosse departing on 8/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to La Crosse

Cheap round-trip flights

American Airlines Logo
5:30 am - 10:24 amDTW-LSE
5h 54m1 stop
American Airlines Logo
10:54 am - 5:35 pmLSE-DTW
5h 41m1 stop
$468American Airlines
Find Deal
Fri, Oct 24 - Sun, Oct 26
American Airlines Logo
7:10 am - 5:45 pmDTW-LSE
11h 35m2 stops
American Airlines Logo
10:54 am - 5:35 pmLSE-DTW
5h 41m1 stop
$474American Airlines
Find Deal
Fri, Oct 24 - Sun, Oct 26
American Airlines Logo
7:10 am - 5:45 pmDTW-LSE
11h 35m2 stops
American Airlines Logo
10:54 am - 6:53 pmLSE-DTW
6h 59m2 stops
$555American Airlines
Find Deal
Fri, Oct 24 - Sun, Oct 26
American Airlines Logo
3:17 pm - 6:09 pmDTW-LSE
3h 52m1 stop
American Airlines Logo
6:21 pm - 11:21 pmLSE-DTW
4h 00m1 stop
$751American Airlines
Find Deal
Mon, Sep 29 - Wed, Oct 1
American Airlines Logo
7:18 pm - 11:17 pmDTW-LSE
4h 59m1 stop
American Airlines Logo
6:00 am - 6:01 pmLSE-DTW
11h 01m2 stops
$757American Airlines
Find Deal
Mon, Sep 29 - Wed, Oct 1
American Airlines Logo
9:18 am - 6:09 pmDTW-LSE
9h 51m2 stops
American Airlines Logo
9:50 am - 6:01 pmLSE-DTW
7h 11m2 stops
$762American Airlines
Find Deal
Mon, Sep 29 - Wed, Oct 1

American Airlines flights from Detroit Metropolitan Wayne County Airport to La Crosse

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to La Crosse flight tickets
American Airlines
Oct 24
DTW5:30 amDetroit Metropolitan Wayne County
5h 54m
1 stop
LSE10:24 amLa Crosse
Oct 26
LSE10:54 amLa Crosse
5h 41m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$468
Find similar
American Airlines
Oct 24
DTW7:10 amDetroit Metropolitan Wayne County
11h 35m
2 stops
LSE5:45 pmLa Crosse
Oct 26
LSE10:54 amLa Crosse
5h 41m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$474
Find similar
American Airlines
Oct 24
DTW7:10 amDetroit Metropolitan Wayne County
11h 35m
2 stops
LSE5:45 pmLa Crosse
Oct 26
LSE10:54 amLa Crosse
6h 59m
2 stops
DTW6:53 pmDetroit Metropolitan Wayne County
$555
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Fri 10/24

5:30 am-10:24 am

1 stop5h 54m

La Crosse

Sun 10/26

10:54 am-5:35 pm

1 stop5h 41m

$468

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Fri 10/24

7:10 am-5:45 pm

2 stops11h 35m

La Crosse

Sun 10/26

10:54 am-5:35 pm

1 stop5h 41m

$474

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Fri 10/24

7:10 am-5:45 pm

2 stops11h 35m

La Crosse

Sun 10/26

10:54 am-6:53 pm

2 stops6h 59m

$555

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 9/29

3:17 pm-6:09 pm

1 stop3h 52m

La Crosse

Wed 10/1

6:21 pm-11:21 pm

1 stop4h 00m

$751

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 9/29

7:18 pm-11:17 pm

1 stop4h 59m

La Crosse

Wed 10/1

6:00 am-6:01 pm

2 stops11h 01m

$757

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 9/29

9:18 am-6:09 pm

2 stops9h 51m

La Crosse

Wed 10/1

9:50 am-6:01 pm

2 stops7h 11m

$762

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 8/20

6:55 am-11:43 am

1 stop5h 48m

$352

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 8/20

7:05 am-6:02 pm

2 stops11h 57m

$509

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to La Crosse from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to La Crosse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Detroit Metropolitan Wayne County to La Crosse?

American Airlines is the most popular carrier operating from Detroit Metropolitan Wayne County to La Crosse

When to book flights from Detroit Metropolitan Wayne County Airport to La Crosse

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to La Crosse according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to La Crosse (DTW to LSE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to La Crosse

Best Price Found

$352

Fastest flight time

3h 52m

Direct flights

None

Airports in La Crosse

1 airport
The best one-way flight to La Crosse from Detroit Metropolitan Wayne County Airport in the past 72 hours is $352. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to La Crosse found on momondo in the last 72 hours is $468.
The fastest flight from Detroit Metropolitan Wayne County Airport to La Crosse takes 3h 52m
There are no direct flights from Detroit Metropolitan Wayne County Airport to La Crosse. Popular non-direct route for this connection is Detroit Metropolitan Wayne County Airport - La Crosse Airport.
There is 1 airport near La Crosse: La Crosse (LSE)
Search flight deals

  • How far is Detroit Metropolitan Wayne County to La Crosse by plane?

    Detroit Metropolitan Wayne County and La Crosse are 412.7 mi apart from one another. By plane, this route typically takes 3h 52m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The necessary travel and health documents for your La Crosse Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to La Crosse?

Best airlines flying from Detroit Metropolitan Wayne County Airport to La Crosse

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to La Crosse with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Winona
Onalaska
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to La Crosse?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to La Crosse from Detroit.

Can I find flights from Detroit to La Crosse with flexible booking policies on momondo?

Yes. All flights to La Crosse from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to La Crosse?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to La Crosse from Detroit.

I’m not ready to book a flight from Detroit to La Crosse right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to La Crosse from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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