Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse from $222

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to La Crosse departing on 7/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to La Crosse

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:33 am - 5:11 pm
DTW
-
LSE
11h 38m
1 stop
American Airlines Logo
12:01 pm - 9:49 am
LSE
-
DTW
20h 48m
1 stop
$371American Airlines
Sat, Jul 18 - Tue, Jul 21
American Airlines Logo
7:00 am - 5:11 pm
DTW
-
LSE
11h 11m
2 stops
American Airlines Logo
5:57 pm - 5:41 pm
LSE
-
DTW
22h 44m
1 stop
$439American Airlines
Sat, Jul 18 - Tue, Jul 21
American Airlines Logo
1:02 pm - 12:19 am
DTW
-
LSE
12h 17m
1 stop
American Airlines Logo
5:28 pm - 10:03 am
LSE
-
DTW
15h 35m
1 stop
$443American Airlines
Wed, Jun 10 - Sun, Jun 14
American Airlines Logo
1:43 pm - 12:19 am
DTW
-
LSE
11h 36m
2 stops
American Airlines Logo
5:28 pm - 10:03 am
LSE
-
DTW
15h 35m
1 stop
$447American Airlines
Thu, Jun 11 - Sun, Jun 14
American Airlines Logo
1:02 pm - 12:19 am
DTW
-
LSE
12h 17m
1 stop
American Airlines Logo
5:33 pm - 4:59 pm
LSE
-
DTW
22h 26m
1 stop
$456American Airlines
Wed, Jun 10 - Sat, Jun 13
Multiple Airlines Logo
8:01 pm - 7:14 pm
DTW
-
LSE
24h 13m
1 stop
Multiple Airlines Logo
5:26 pm - 4:53 pm
LSE
-
DTW
22h 27m
2 stops
$463Multiple Airlines
Thu, Jun 11 - Thu, Jun 18
American Airlines Logo
6:45 am - 12:19 am
DTW
-
LSE
18h 34m
1 stop
American Airlines Logo
5:28 pm - 4:59 pm
LSE
-
DTW
22h 31m
1 stop
$476American Airlines
Thu, Jun 4 - Sun, Jun 7
American Airlines Logo
8:58 pm - 12:19 am
DTW
-
LSE
4h 21m
1 stop
American Airlines Logo
6:00 am - 12:32 pm
LSE
-
DTW
5h 32m
1 stop
$498American Airlines
Tue, Jun 9 - Sat, Jun 13
American Airlines Logo
5:36 pm - 12:19 am
DTW
-
LSE
7h 43m
1 stop
American Airlines Logo
5:25 pm - 10:03 am
LSE
-
DTW
15h 38m
1 stop
$503American Airlines
Sat, Jun 20 - Mon, Jun 22
American Airlines Logo
1:43 pm - 12:19 am
DTW
-
LSE
11h 36m
2 stops
American Airlines Logo
6:00 am - 12:32 pm
LSE
-
DTW
5h 32m
1 stop
$504American Airlines
Tue, Jun 9 - Sat, Jun 13

American Airlines flights from Detroit Metropolitan Wayne County Airport to La Crosse

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to La Crosse flight tickets
American Airlines
Jul 18
DTW6:33 amDetroit Metropolitan Wayne County
11h 38m
1 stop
LSE5:11 pmLa Crosse
Jul 21
LSE12:01 pmLa Crosse
20h 48m
1 stop
DTW9:49 amDetroit Metropolitan Wayne County
$371
American Airlines
Jul 18
DTW7:00 amDetroit Metropolitan Wayne County
11h 11m
2 stops
LSE5:11 pmLa Crosse
Jul 21
LSE5:57 pmLa Crosse
22h 44m
1 stop
DTW5:41 pmDetroit Metropolitan Wayne County
$439
American Airlines
Jun 10
DTW1:02 pmDetroit Metropolitan Wayne County
12h 17m
1 stop
LSE12:19 amLa Crosse
Jun 14
LSE5:28 pmLa Crosse
15h 35m
1 stop
DTW10:03 amDetroit Metropolitan Wayne County
$443

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 7/18

6:33 am-5:11 pm

1 stop11h 38m

La Crosse

Tue 7/21

12:01 pm-9:49 am

1 stop20h 48m

$371

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 7/18

7:00 am-5:11 pm

2 stops11h 11m

La Crosse

Tue 7/21

5:57 pm-5:41 pm

1 stop22h 44m

$439

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 6/10

1:02 pm-12:19 am

1 stop12h 17m

La Crosse

Sun 6/14

5:28 pm-10:03 am

1 stop15h 35m

$443

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 6/11

1:43 pm-12:19 am

2 stops11h 36m

La Crosse

Sun 6/14

5:28 pm-10:03 am

1 stop15h 35m

$447

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 6/10

1:02 pm-12:19 am

1 stop12h 17m

La Crosse

Sat 6/13

5:33 pm-4:59 pm

1 stop22h 26m

$456

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 6/11

8:01 pm-7:14 pm

1 stop24h 13m

La Crosse

Thu 6/18

5:26 pm-4:53 pm

2 stops22h 27m

$463

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 6/4

6:45 am-12:19 am

1 stop18h 34m

La Crosse

Sun 6/7

5:28 pm-4:59 pm

1 stop22h 31m

$476
Quickest round-trip

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 6/9

8:58 pm-12:19 am

1 stop4h 21m

La Crosse

Sat 6/13

6:00 am-12:32 pm

1 stop5h 32m

$498

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 6/20

5:36 pm-12:19 am

1 stop7h 43m

La Crosse

Mon 6/22

5:25 pm-10:03 am

1 stop15h 38m

$503

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 6/9

1:43 pm-12:19 am

2 stops11h 36m

La Crosse

Sat 6/13

6:00 am-12:32 pm

1 stop5h 32m

$504

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to La Crosse from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to La Crosse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Detroit Metropolitan Wayne County to La Crosse?

American Airlines is the most popular carrier operating from Detroit Metropolitan Wayne County to La Crosse

When to book flights from Detroit Metropolitan Wayne County Airport to La Crosse

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to La Crosse according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to La Crosse (DTW to LSE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to La Crosse

Fastest flight time

5h 42m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to La Crosse takes 5h 42m
There are no direct flights from Detroit Metropolitan Wayne County Airport to La Crosse. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to La Crosse.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to La Crosse

  • How far is Detroit Metropolitan Wayne County to La Crosse by plane?

    Detroit Metropolitan Wayne County and La Crosse are 412.7 mi apart from one another. By plane, this route typically takes 5h 42m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport refresh daily.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The necessary travel and health documents for your La Crosse Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Onalaska
Winona
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to La Crosse?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to La Crosse from Detroit.

Can I find flights from Detroit to La Crosse with flexible booking policies on momondo?

Yes. All flights to La Crosse from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to La Crosse?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to La Crosse from Detroit.

I’m not ready to book a flight from Detroit to La Crosse right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to La Crosse from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your La Crosse trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 6/15
Mon 6/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States