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Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse from $468

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to La Crosse departing on 1/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to La Crosse

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:08 pm - 4:16 pm
DTW
-
LSE
4h 08m1 stop
American Airlines Logo
11:37 am - 5:25 pm
LSE
-
DTW
4h 48m1 stop
$468American Airlines
Thu, Jan 15 - Thu, Jan 22
American Airlines Logo
8:00 am - 11:07 am
DTW
-
LSE
4h 07m1 stop
American Airlines Logo
11:37 am - 10:30 pm
LSE
-
DTW
9h 53m2 stops
$474American Airlines
Thu, Jan 15 - Thu, Jan 22
American Airlines Logo
12:54 pm - 4:16 pm
DTW
-
LSE
4h 22m1 stop
American Airlines Logo
11:37 am - 9:58 pm
LSE
-
DTW
9h 21m2 stops
$475American Airlines
Sat, Jan 17 - Sun, Jan 18
American Airlines Logo
7:05 am - 4:16 pm
DTW
-
LSE
10h 11m2 stops
American Airlines Logo
6:00 am - 4:23 pm
LSE
-
DTW
9h 23m2 stops
$479American Airlines
Thu, Jan 15 - Thu, Jan 22
American Airlines Logo
10:10 am - 7:36 pm
DTW
-
LSE
10h 26m2 stops
American Airlines Logo
8:06 pm - 2:20 am
LSE
-
DTW
5h 14m1 stop
$523American Airlines
Wed, Dec 31 - Sun, Jan 4
American Airlines Logo
10:16 am - 5:39 pm
DTW
-
LSE
8h 23m2 stops
American Airlines Logo
6:00 am - 4:33 pm
LSE
-
DTW
9h 33m2 stops
$525American Airlines
Thu, Feb 12 - Mon, Feb 16
American Airlines Logo
12:54 pm - 4:16 pm
DTW
-
LSE
4h 22m1 stop
American Airlines Logo
11:37 am - 5:25 pm
LSE
-
DTW
4h 48m1 stop
$536American Airlines
Sat, Jan 17 - Sun, Jan 18
American Airlines Logo
7:16 am - 7:36 pm
DTW
-
LSE
13h 20m2 stops
American Airlines Logo
5:45 am - 4:29 pm
LSE
-
DTW
9h 44m2 stops
$717American Airlines
Wed, Dec 31 - Sun, Jan 4
American Airlines Logo
8:05 am - 7:36 pm
DTW
-
LSE
12h 31m1 stop
American Airlines Logo
8:06 pm - 2:20 am
LSE
-
DTW
5h 14m1 stop
$752American Airlines
Wed, Dec 31 - Sun, Jan 4
American Airlines Logo
1:08 pm - 5:39 pm
DTW
-
LSE
5h 31m1 stop
American Airlines Logo
10:03 am - 4:49 pm
LSE
-
DTW
5h 46m1 stop
$838American Airlines
Sun, Feb 15 - Mon, Feb 16

American Airlines flights from Detroit Metropolitan Wayne County Airport to La Crosse

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to La Crosse flight tickets
American Airlines
Jan 15
DTW1:08 pmDetroit Metropolitan Wayne County
4h 08m
1 stop
LSE4:16 pmLa Crosse
Jan 22
LSE11:37 amLa Crosse
4h 48m
1 stop
DTW5:25 pmDetroit Metropolitan Wayne County
$468
Find similar
American Airlines
Jan 15
DTW8:00 amDetroit Metropolitan Wayne County
4h 07m
1 stop
LSE11:07 amLa Crosse
Jan 22
LSE11:37 amLa Crosse
9h 53m
2 stops
DTW10:30 pmDetroit Metropolitan Wayne County
$474
Find similar
American Airlines
Jan 17
DTW12:54 pmDetroit Metropolitan Wayne County
4h 22m
1 stop
LSE4:16 pmLa Crosse
Jan 18
LSE11:37 amLa Crosse
9h 21m
2 stops
DTW9:58 pmDetroit Metropolitan Wayne County
$475
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 1/15

1:08 pm-4:16 pm

1 stop4h 08m

La Crosse

Thu 1/22

11:37 am-5:25 pm

1 stop4h 48m

$468

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 1/15

8:00 am-11:07 am

1 stop4h 07m

La Crosse

Thu 1/22

11:37 am-10:30 pm

2 stops9h 53m

$474

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 1/17

12:54 pm-4:16 pm

1 stop4h 22m

La Crosse

Sun 1/18

11:37 am-9:58 pm

2 stops9h 21m

$475

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 1/15

7:05 am-4:16 pm

2 stops10h 11m

La Crosse

Thu 1/22

6:00 am-4:23 pm

2 stops9h 23m

$479

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 12/31

10:10 am-7:36 pm

2 stops10h 26m

La Crosse

Sun 1/4

8:06 pm-2:20 am

1 stop5h 14m

$523

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/12

10:16 am-5:39 pm

2 stops8h 23m

La Crosse

Mon 2/16

6:00 am-4:33 pm

2 stops9h 33m

$525

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sat 1/17

12:54 pm-4:16 pm

1 stop4h 22m

La Crosse

Sun 1/18

11:37 am-5:25 pm

1 stop4h 48m

$536

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 12/31

7:16 am-7:36 pm

2 stops13h 20m

La Crosse

Sun 1/4

5:45 am-4:29 pm

2 stops9h 44m

$717

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Wed 12/31

8:05 am-7:36 pm

1 stop12h 31m

La Crosse

Sun 1/4

8:06 pm-2:20 am

1 stop5h 14m

$752

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sun 2/15

1:08 pm-5:39 pm

1 stop5h 31m

La Crosse

Mon 2/16

10:03 am-4:49 pm

1 stop5h 46m

$838

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Detroit Metropolitan Wayne County Airport to La Crosse

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to La Crosse according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to La Crosse (DTW to LSE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to La Crosse

Fastest flight time

4h 08m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to La Crosse takes 4h 08m
There are no direct flights from Detroit Metropolitan Wayne County Airport to La Crosse. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to La Crosse.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to La Crosse by plane?

    Detroit Metropolitan Wayne County and La Crosse are 412.7 mi apart from one another. By plane, this route typically takes 4h 08m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The necessary travel and health documents for your La Crosse Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to La Crosse?

Best airlines flying from Detroit Metropolitan Wayne County Airport to La Crosse

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to La Crosse with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $468Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

  • How do I get Price Alerts for flights from Detroit Metropolitan Wayne County Airport to La Crosse?

    Confirm your travel details to search for the latest offers for flights from Detroit Metropolitan Wayne County Airport to La Crosse. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from Detroit Metropolitan Wayne County Airport to La Crosse with momondo?

    With “Price Forecast”, learn how soon you should book your flight in advance. Down to the day of week and time of day, our information can inform you on the ideal time to book to save on your travel. Our “Price Calendar” shows you at a quick glance when to book your travel for lower rates. By setting “Price Alerts” you can monitor changes in price and target the ideal time to book. Search for your trip destination by budget amount via our “Explore” feature. Whether you’re looking for ideas for your next travel adventure or cost-cutting tips, our “Discover” content is a great place to start.

  • How does momondo find its flight prices?

    We compare prices from 700+ competitors to help you find the price that works best for you. momondo operates in over 30 international markets, bringing you access to a wide range of fares and deals. Search for your travel using momondo for a diverse range of options from airlines and OTAs.

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Onalaska
Winona
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to La Crosse?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to La Crosse from Detroit.

Can I find flights from Detroit to La Crosse with flexible booking policies on momondo?

Yes. All flights to La Crosse from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to La Crosse?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to La Crosse from Detroit.

I’m not ready to book a flight from Detroit to La Crosse right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to La Crosse from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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