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Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse from $293

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to La Crosse departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to La Crosse

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:45 am - 11:02 am
DTW
-
LSE
6h 17m
1 stop
American Airlines Logo
11:34 am - 4:50 pm
LSE
-
DTW
4h 16m
1 stop
$488American Airlines
Sun, Mar 8 - Wed, Mar 18
American Airlines Logo
5:45 am - 9:18 am
DTW
-
LSE
4h 33m
1 stop
American Airlines Logo
6:29 pm - 12:31 am
LSE
-
DTW
5h 02m
1 stop
$491American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
3:37 pm - 11:36 pm
DTW
-
LSE
8h 59m
2 stops
American Airlines Logo
6:29 pm - 12:31 am
LSE
-
DTW
5h 02m
1 stop
$494American Airlines
Sun, Mar 8 - Wed, Mar 18
American Airlines Logo
5:45 am - 9:18 am
DTW
-
LSE
4h 33m
1 stop
American Airlines Logo
9:48 am - 9:53 pm
LSE
-
DTW
11h 05m
2 stops
$497American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
3:37 pm - 11:36 pm
DTW
-
LSE
8h 59m
2 stops
American Airlines Logo
11:34 am - 11:03 pm
LSE
-
DTW
10h 29m
2 stops
$499American Airlines
Sun, Mar 8 - Wed, Mar 18
American Airlines Logo
6:41 am - 2:06 pm
DTW
-
LSE
8h 25m
2 stops
American Airlines Logo
9:48 am - 9:53 pm
LSE
-
DTW
11h 05m
2 stops
$502American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
5:45 am - 11:01 am
DTW
-
LSE
6h 16m
1 stop
American Airlines Logo
11:27 am - 4:53 pm
LSE
-
DTW
4h 26m
1 stop
$537American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
7:14 am - 5:59 pm
DTW
-
LSE
11h 45m
2 stops
American Airlines Logo
11:27 am - 4:53 pm
LSE
-
DTW
4h 26m
1 stop
$543American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
10:11 am - 5:59 pm
DTW
-
LSE
8h 48m
2 stops
American Airlines Logo
5:20 am - 5:41 pm
LSE
-
DTW
11h 21m
2 stops
$548American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
8:18 am - 11:01 am
DTW
-
LSE
3h 43m
1 stop
American Airlines Logo
5:20 am - 9:56 am
LSE
-
DTW
3h 36m
1 stop
$580American Airlines
Thu, Feb 26 - Mon, Mar 2

American Airlines flights from Detroit Metropolitan Wayne County Airport to La Crosse

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to La Crosse flight tickets
American Airlines
Mar 8
DTW5:45 amDetroit Metropolitan Wayne County
6h 17m
1 stop
LSE11:02 amLa Crosse
Mar 18
LSE11:34 amLa Crosse
4h 16m
1 stop
DTW4:50 pmDetroit Metropolitan Wayne County
$488
American Airlines
Mar 3
DTW5:45 amDetroit Metropolitan Wayne County
4h 33m
1 stop
LSE9:18 amLa Crosse
Mar 10
LSE6:29 pmLa Crosse
5h 02m
1 stop
DTW12:31 amDetroit Metropolitan Wayne County
$491
American Airlines
Mar 8
DTW3:37 pmDetroit Metropolitan Wayne County
8h 59m
2 stops
LSE11:36 pmLa Crosse
Mar 18
LSE6:29 pmLa Crosse
5h 02m
1 stop
DTW12:31 amDetroit Metropolitan Wayne County
$494

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sun 3/8

5:45 am-11:02 am

1 stop6h 17m

La Crosse

Wed 3/18

11:34 am-4:50 pm

1 stop4h 16m

$488

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 3/3

5:45 am-9:18 am

1 stop4h 33m

La Crosse

Tue 3/10

6:29 pm-12:31 am

1 stop5h 02m

$491

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sun 3/8

3:37 pm-11:36 pm

2 stops8h 59m

La Crosse

Wed 3/18

6:29 pm-12:31 am

1 stop5h 02m

$494

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 3/3

5:45 am-9:18 am

1 stop4h 33m

La Crosse

Tue 3/10

9:48 am-9:53 pm

2 stops11h 05m

$497

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Sun 3/8

3:37 pm-11:36 pm

2 stops8h 59m

La Crosse

Wed 3/18

11:34 am-11:03 pm

2 stops10h 29m

$499

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 3/3

6:41 am-2:06 pm

2 stops8h 25m

La Crosse

Tue 3/10

9:48 am-9:53 pm

2 stops11h 05m

$502

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/12

5:45 am-11:01 am

1 stop6h 16m

La Crosse

Sat 2/14

11:27 am-4:53 pm

1 stop4h 26m

$537

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/12

7:14 am-5:59 pm

2 stops11h 45m

La Crosse

Sat 2/14

11:27 am-4:53 pm

1 stop4h 26m

$543

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/12

10:11 am-5:59 pm

2 stops8h 48m

La Crosse

Sat 2/14

5:20 am-5:41 pm

2 stops11h 21m

$548

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/26

8:18 am-11:01 am

1 stop3h 43m

La Crosse

Mon 3/2

5:20 am-9:56 am

1 stop3h 36m

$580

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to La Crosse

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Detroit Metropolitan Wayne County to La Crosse?

American Airlines is the most popular carrier operating from Detroit Metropolitan Wayne County to La Crosse

When to book flights from Detroit Metropolitan Wayne County Airport to La Crosse

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to La Crosse according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to La Crosse (DTW to LSE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to La Crosse

Fastest flight time

3h 43m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to La Crosse takes 3h 43m
There are no direct flights from Detroit Metropolitan Wayne County Airport to La Crosse. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to La Crosse.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to La Crosse by plane?

    Detroit Metropolitan Wayne County and La Crosse are 412.7 mi apart from one another. By plane, this route typically takes 3h 43m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to La Crosse Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to La Crosse Airport.

  • What documentation or ID do you need to fly to La Crosse Airport?

    The necessary travel and health documents for your La Crosse Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to La Crosse?

Best airlines flying from Detroit Metropolitan Wayne County Airport to La Crosse

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to La Crosse with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $414Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Onalaska
Winona
Decorah
Harpers Ferry
Lansing

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to La Crosse?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to La Crosse from Detroit.

Can I find flights from Detroit to La Crosse with flexible booking policies on momondo?

Yes. All flights to La Crosse from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to La Crosse?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to La Crosse from Detroit.

I’m not ready to book a flight from Detroit to La Crosse right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to La Crosse from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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