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Cheap flights from Detroit Metropolitan Wayne County Airport to Key West from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Key West departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:09 pm - 10:21 am
DTW
-
EYW
17h 12m
2 stops
Multiple Airlines Logo
11:51 am - 10:21 am
EYW
-
DTW
22h 30m
1 stop
$235Multiple Airlines
Sat, Apr 18 - Wed, Apr 22
Multiple Airlines Logo
10:10 pm - 9:09 am
DTW
-
EYW
10h 59m
1 stop
Multiple Airlines Logo
11:46 am - 12:39 am
EYW
-
DTW
12h 53m
2 stops
$245Multiple Airlines
Sun, May 3 - Wed, May 6
Multiple Airlines Logo
12:44 pm - 2:01 pm
DTW
-
EYW
25h 17m
1 stop
Multiple Airlines Logo
1:14 pm - 11:59 pm
EYW
-
DTW
34h 45m
2 stops
$249Multiple Airlines
Thu, May 28 - Tue, Jun 2
Multiple Airlines Logo
10:10 pm - 9:09 am
DTW
-
EYW
10h 59m
1 stop
Multiple Airlines Logo
4:22 pm - 9:10 am
EYW
-
DTW
16h 48m
2 stops
$250Multiple Airlines
Sun, Apr 26 - Thu, Apr 30
Multiple Airlines Logo
4:17 pm - 12:21 pm
DTW
-
EYW
20h 04m
2 stops
Multiple Airlines Logo
9:49 am - 9:11 pm
EYW
-
DTW
11h 22m
1 stop
$251Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
5:25 pm - 12:26 pm
DTW
-
EYW
19h 01m
1 stop
Multiple Airlines Logo
9:49 am - 11:45 am
EYW
-
DTW
25h 56m
2 stops
$255Multiple Airlines
Sun, Apr 19 - Fri, Apr 24
Multiple Airlines Logo
4:17 pm - 12:21 pm
DTW
-
EYW
20h 04m
2 stops
Multiple Airlines Logo
9:49 am - 9:11 pm
EYW
-
DTW
11h 22m
1 stop
$256Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
9:28 pm - 12:21 pm
DTW
-
EYW
14h 53m
1 stop
Multiple Airlines Logo
9:49 am - 9:11 pm
EYW
-
DTW
11h 22m
1 stop
$260Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
12:44 pm - 2:01 pm
DTW
-
EYW
25h 17m
1 stop
Multiple Airlines Logo
2:51 pm - 12:00 pm
EYW
-
DTW
21h 09m
1 stop
$264Multiple Airlines
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
10:05 am - 12:21 pm
DTW
-
EYW
26h 16m
1 stop
Multiple Airlines Logo
9:49 am - 9:11 pm
EYW
-
DTW
11h 22m
1 stop
$265Multiple Airlines
Mon, Apr 13 - Fri, Apr 17

Spirit Airlines flights from Detroit Metropolitan Wayne County Airport to Key West

Our best Spirit Airlines deals on Detroit Metropolitan Wayne County Airport to Key West flight tickets
Spirit Airlines
Apr 12
DTW1:28 pmDetroit Metropolitan Wayne County
24h 09m
3 stops
EYW1:37 pmKey West
Apr 14
EYW12:25 pmKey West
11h 34m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$400
Spirit Airlines
Apr 13
DTW5:45 amDetroit Metropolitan Wayne County
7h 52m
1 stop
EYW1:37 pmKey West
Apr 17
EYW2:30 pmKey West
26h 48m
3 stops
DTW5:18 pmDetroit Metropolitan Wayne County
$407
Spirit Airlines
Apr 13
DTW8:15 amDetroit Metropolitan Wayne County
5h 22m
1 stop
EYW1:37 pmKey West
Apr 17
EYW2:30 pmKey West
26h 48m
3 stops
DTW5:18 pmDetroit Metropolitan Wayne County
$408

Delta flights from Detroit Metropolitan Wayne County Airport to Key West

Our best Delta deals on Detroit Metropolitan Wayne County Airport to Key West flight tickets
Delta
May 2
DTW5:20 amDetroit Metropolitan Wayne County
5h 26m
1 stop
EYW10:46 amKey West
May 6
EYW6:23 pmKey West
6h 21m
1 stop
DTW12:44 amDetroit Metropolitan Wayne County
$323
Delta
Apr 15
DTW7:39 amDetroit Metropolitan Wayne County
6h 05m
1 stop
EYW1:44 pmKey West
Apr 22
EYW7:33 amKey West
5h 24m
1 stop
DTW12:57 pmDetroit Metropolitan Wayne County
$374
Delta
Apr 15
DTW5:20 amDetroit Metropolitan Wayne County
5h 26m
1 stop
EYW10:46 amKey West
Apr 22
EYW6:23 pmKey West
5h 16m
1 stop
DTW11:39 pmDetroit Metropolitan Wayne County
$414

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sat 4/18

5:09 pm-10:21 am

2 stops17h 12m

Key West

Wed 4/22

11:51 am-10:21 am

1 stop22h 30m

$235
Quickest round-trip

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sun 5/3

10:10 pm-9:09 am

1 stop10h 59m

Key West

Wed 5/6

11:46 am-12:39 am

2 stops12h 53m

$245

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Thu 5/28

12:44 pm-2:01 pm

1 stop25h 17m

Key West

Tue 6/2

1:14 pm-11:59 pm

2 stops34h 45m

$249

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sun 4/26

10:10 pm-9:09 am

1 stop10h 59m

Key West

Thu 4/30

4:22 pm-9:10 am

2 stops16h 48m

$250

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Mon 4/13

4:17 pm-12:21 pm

2 stops20h 04m

Key West

Fri 4/17

9:49 am-9:11 pm

1 stop11h 22m

$251

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Sun 4/19

5:25 pm-12:26 pm

1 stop19h 01m

Key West

Fri 4/24

9:49 am-11:45 am

2 stops25h 56m

$255

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Mon 4/13

4:17 pm-12:21 pm

2 stops20h 04m

Key West

Fri 4/17

9:49 am-9:11 pm

1 stop11h 22m

$256

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Mon 4/13

9:28 pm-12:21 pm

1 stop14h 53m

Key West

Fri 4/17

9:49 am-9:11 pm

1 stop11h 22m

$260

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Thu 5/28

12:44 pm-2:01 pm

1 stop25h 17m

Key West

Mon 6/1

2:51 pm-12:00 pm

1 stop21h 09m

$264

DetroitKey West

DTW - EYW

DTWEYW

Detroit Metropolitan Wayne County

Mon 4/13

10:05 am-12:21 pm

1 stop26h 16m

Key West

Fri 4/17

9:49 am-9:11 pm

1 stop11h 22m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Key West?

What is the cheapest month to fly to Key West?

In general, January is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $348. If you are unable to visit Key West during the month of January, then departing from Detroit Metropolitan Wayne County Airport during the month November is also very affordable. Most momondo users find prices during this month for around $379.

How far in advance should I book a flight to Key West?

You are more likely to see cheaper flights to Key West from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Key West for around $444 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Key West from Detroit Metropolitan Wayne County Airport for as low as $281 on momondo.

When to book flights from Detroit Metropolitan Wayne County Airport to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Key West (DTW to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Key West

Fastest flight time

5h 54m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Key West takes 5h 54m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Key West. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Key West.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Key West

  • How far is Detroit Metropolitan Wayne County to Key West by plane?

    A flight from Detroit Metropolitan Wayne County to Key West will travel around 1223.0 mi. Typically, this will take 5h 54m by plane in normal conditions.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Key West Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Key West Airport refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Key West Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Key West Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The required travel and health documents for your Key West Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Key West Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Key West?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Key West

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Key West with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $130Free CancellationRating
6.3
8,578 reviews
Search Spirit Airlines flights
DeltaPriceFrom $247Free CancellationRating
7.9
8,374 reviews
Search Delta flights
United AirlinesPriceFrom $268Free CancellationRating
7.4
9,538 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.1
11,552 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Key West?

It is quick and easy to find Detroit to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Detroit to Key West with flexible booking policies on momondo?

All flight searches from Detroit to Key West on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Key West?

momondo helps you find the best flight between Detroit and Key West by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Key West right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Key West, momondo offers a useful price alert feature which will track prices for flights to Key West from Detroit and alert you when they change.

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