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Cheap flights from Des Moines to Luxembourg from $443

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Luxembourg departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Luxembourg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:47 pm - 1:50 pm
DSM
-
LUX
13h 03m
2 stops
Multiple Airlines Logo
10:25 am - 8:45 pm
LUX
-
DSM
17h 20m
2 stops
$478Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Air France Logo
10:51 am - 10:35 am
DSM
-
LUX
16h 44m
2 stops
Air France Logo
7:30 am - 4:54 pm
LUX
-
DSM
16h 24m
2 stops
$484Air France
Tue, Mar 31 - Tue, Apr 7
KLM Logo
10:28 am - 9:55 am
DSM
-
LUX
16h 27m
2 stops
KLM Logo
6:25 pm - 3:42 pm
LUX
-
DSM
28h 17m
2 stops
$581KLM
Mon, Mar 30 - Mon, Apr 6
Lufthansa Logo
6:59 pm - 7:30 pm
DSM
-
LUX
17h 31m
2 stops
Lufthansa Logo
8:10 pm - 9:27 pm
LUX
-
DSM
32h 17m
2 stops
$588Lufthansa
Mon, Mar 30 - Mon, Apr 6
Lufthansa Logo
6:59 pm - 7:30 pm
DSM
-
LUX
17h 31m
2 stops
Lufthansa Logo
8:10 pm - 10:59 pm
LUX
-
DSM
33h 49m
2 stops
$591Lufthansa
Mon, Mar 30 - Mon, Apr 6
Lufthansa Logo
1:10 pm - 7:30 pm
DSM
-
LUX
23h 20m
2 stops
Lufthansa Logo
8:10 pm - 10:59 pm
LUX
-
DSM
33h 49m
2 stops
$612Lufthansa
Mon, Mar 30 - Mon, Apr 6
Lufthansa Logo
6:49 pm - 8:40 am
DSM
-
LUX
31h 51m
2 stops
Lufthansa Logo
8:10 pm - 9:27 pm
LUX
-
DSM
32h 17m
2 stops
$655Lufthansa
Sat, Mar 28 - Sat, Apr 4
Lufthansa Logo
6:49 pm - 12:50 pm
DSM
-
LUX
36h 01m
2 stops
Lufthansa Logo
8:10 pm - 10:59 pm
LUX
-
DSM
33h 49m
2 stops
$679Lufthansa
Sat, Mar 28 - Sat, Apr 4
Air France Logo
5:47 pm - 1:50 pm
DSM
-
LUX
13h 03m
2 stops
Air France Logo
6:25 pm - 4:33 pm
LUX
-
DSM
53h 08m
2 stops
$722Air France
Sun, Mar 29 - Sun, Apr 5
Multiple Airlines Logo
6:59 pm - 7:30 pm
DSM
-
LUX
17h 31m
2 stops
Multiple Airlines Logo
6:05 am - 9:27 pm
LUX
-
DSM
22h 22m
3 stops
$733Multiple Airlines
Mon, Mar 30 - Mon, Apr 6

Lufthansa flights from Des Moines to Luxembourg

Our best Lufthansa deals on Des Moines to Luxembourg flight tickets
Lufthansa
Mar 30
DSM6:59 pmDes Moines
17h 31m
2 stops
LUX7:30 pmLuxembourg
Apr 6
LUX8:10 pmLuxembourg
32h 17m
2 stops
DSM9:27 pmDes Moines
$588
Lufthansa
Mar 30
DSM6:59 pmDes Moines
17h 31m
2 stops
LUX7:30 pmLuxembourg
Apr 6
LUX8:10 pmLuxembourg
33h 49m
2 stops
DSM10:59 pmDes Moines
$591
Lufthansa
Mar 30
DSM1:10 pmDes Moines
23h 20m
2 stops
LUX7:30 pmLuxembourg
Apr 6
LUX8:10 pmLuxembourg
33h 49m
2 stops
DSM10:59 pmDes Moines
$612

Air Canada flights from Des Moines to Luxembourg

Our best Air Canada deals on Des Moines to Luxembourg flight tickets
Air Canada
Mar 31
DSM1:10 pmDes Moines
17h 25m
3 stops
LUX1:35 pmLuxembourg
Apr 7
LUX6:05 amLuxembourg
19h 10m
3 stops
DSM6:15 pmDes Moines
$960
Air Canada
Mar 28
DSM11:26 amDes Moines
19h 34m
3 stops
LUX1:00 pmLuxembourg
Apr 4
LUX6:05 amLuxembourg
19h 10m
3 stops
DSM6:15 pmDes Moines
$1,168
Air Canada
Mar 28
DSM11:26 amDes Moines
19h 34m
3 stops
LUX1:00 pmLuxembourg
Apr 4
LUX6:05 amLuxembourg
19h 10m
3 stops
DSM6:15 pmDes Moines
$1,171

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 3/31

5:47 pm-1:50 pm

2 stops13h 03m

Luxembourg

Tue 4/7

10:25 am-8:45 pm

2 stops17h 20m

$478

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 3/31

10:51 am-10:35 am

2 stops16h 44m

Luxembourg

Tue 4/7

7:30 am-4:54 pm

2 stops16h 24m

$484

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 3/30

10:28 am-9:55 am

2 stops16h 27m

Luxembourg

Mon 4/6

6:25 pm-3:42 pm

2 stops28h 17m

$581

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 3/30

6:59 pm-7:30 pm

2 stops17h 31m

Luxembourg

Mon 4/6

8:10 pm-9:27 pm

2 stops32h 17m

$588

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 3/30

6:59 pm-7:30 pm

2 stops17h 31m

Luxembourg

Mon 4/6

8:10 pm-10:59 pm

2 stops33h 49m

$591

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 3/30

1:10 pm-7:30 pm

2 stops23h 20m

Luxembourg

Mon 4/6

8:10 pm-10:59 pm

2 stops33h 49m

$612

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 3/28

6:49 pm-8:40 am

2 stops31h 51m

Luxembourg

Sat 4/4

8:10 pm-9:27 pm

2 stops32h 17m

$655

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 3/28

6:49 pm-12:50 pm

2 stops36h 01m

Luxembourg

Sat 4/4

8:10 pm-10:59 pm

2 stops33h 49m

$679

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 3/29

5:47 pm-1:50 pm

2 stops13h 03m

Luxembourg

Sun 4/5

6:25 pm-4:33 pm

2 stops53h 08m

$722

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 3/30

6:59 pm-7:30 pm

2 stops17h 31m

Luxembourg

Mon 4/6

6:05 am-9:27 pm

3 stops22h 22m

$733

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Luxembourg from

How to get the cheapest flight ticket from Des Moines to Luxembourg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Luxembourg?

Lufthansa, Air France, and Air Canada are the most popular carriers operating from Des Moines to Luxembourg

Cheap Des Moines to Luxembourg flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Luxembourg

Fastest flight time

13h 03m

Direct flights

None
The fastest flight from Des Moines to Luxembourg takes 13h 03m
There are no direct flights from Des Moines to Luxembourg. There are no popular flight routes from Des Moines to Luxembourg.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Luxembourg?

    Prices for flights from Des Moines Airport to Luxembourg were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Luxembourg?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Luxembourg.

  • What documentation or ID do you need to fly to Luxembourg?

    The necessary travel and health documents for your Luxembourg trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Luxembourg?

It is quick and easy to find Des Moines to Luxembourg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Luxembourg that suits you.

Can I find flights from Des Moines to Luxembourg with flexible booking policies on momondo?

Yes. All flights to Luxembourg from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Luxembourg?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Luxembourg from Des Moines.

I’m not ready to book a flight from Des Moines to Luxembourg right now. Can momondo alert me if prices change?

Price alerts on flights to Luxembourg from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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