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Cheap flights from Des Moines to Luxembourg from $648

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Luxembourg departing on 3/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Luxembourg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
6:45 pm - 10:00 pmDSM-LUX
21h 15m2 stops
Lufthansa Logo
8:20 am - 5:33 pmLUX-DSM
16h 13m2 stops
$648Lufthansa
Find Deal
Fri, Mar 27 - Tue, Mar 31
Multiple Airlines Logo
10:20 am - 10:25 amDSM-LUX
17h 05m2 stops
Multiple Airlines Logo
6:20 pm - 4:41 pmLUX-DSM
29h 21m2 stops
$679Multiple Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
Multiple Airlines Logo
6:33 pm - 10:35 amDSM-LUX
33h 02m2 stops
Multiple Airlines Logo
2:45 pm - 8:02 pmLUX-DSM
36h 17m2 stops
$822Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Dec 23
Multiple Airlines Logo
2:59 pm - 2:10 pmDSM-LUX
16h 11m2 stops
Multiple Airlines Logo
7:30 am - 4:41 pmLUX-DSM
16h 11m2 stops
$829Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Dec 23
Multiple Airlines Logo
10:20 am - 10:25 amDSM-LUX
17h 05m2 stops
Multiple Airlines Logo
7:30 am - 4:52 pmLUX-DSM
40h 22m2 stops
$832Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Dec 23
Lufthansa Logo
11:35 am - 6:00 pmDSM-LUX
23h 25m2 stops
Lufthansa Logo
2:30 pm - 7:29 pmLUX-DSM
35h 59m2 stops
$953Lufthansa
Find Deal
Tue, Dec 16 - Tue, Dec 23
Multiple Airlines Logo
8:00 am - 10:00 amDSM-LUX
19h 00m3 stops
Multiple Airlines Logo
6:55 am - 6:05 pmLUX-DSM
18h 10m2 stops
$1,104Multiple Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
Multiple Airlines Logo
11:35 am - 6:00 pmDSM-LUX
23h 25m3 stops
Multiple Airlines Logo
5:00 pm - 7:29 pmLUX-DSM
33h 29m3 stops
$1,150Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Dec 23
Multiple Airlines Logo
8:00 am - 4:50 pmDSM-LUX
25h 50m3 stops
Multiple Airlines Logo
7:05 am - 11:30 pmLUX-DSM
23h 25m3 stops
$1,359Multiple Airlines
Find Deal
Mon, Dec 15 - Mon, Dec 22
Multiple Airlines Logo
11:35 am - 10:00 amDSM-LUX
15h 25m3 stops
Multiple Airlines Logo
9:30 am - 9:40 pmLUX-DSM
19h 10m2 stops
$1,552Multiple Airlines
Find Deal
Tue, Dec 16 - Tue, Dec 23

Lufthansa flights from Des Moines to Luxembourg

Our best Lufthansa deals on Des Moines to Luxembourg flight tickets
Lufthansa
Mar 27
DSM6:45 pmDes Moines
21h 15m
2 stops
LUX10:00 pmLuxembourg
Mar 31
LUX8:20 amLuxembourg
16h 13m
2 stops
DSM5:33 pmDes Moines
$648
Find similar
Lufthansa
Dec 16
DSM11:35 amDes Moines
23h 25m
2 stops
LUX6:00 pmLuxembourg
Dec 23
LUX2:30 pmLuxembourg
35h 59m
2 stops
DSM7:29 pmDes Moines
$953
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 3/27

6:45 pm-10:00 pm

2 stops21h 15m

Luxembourg

Tue 3/31

8:20 am-5:33 pm

2 stops16h 13m

$648

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 12/15

10:20 am-10:25 am

2 stops17h 05m

Luxembourg

Mon 12/22

6:20 pm-4:41 pm

2 stops29h 21m

$679

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 12/16

6:33 pm-10:35 am

2 stops33h 02m

Luxembourg

Tue 12/23

2:45 pm-8:02 pm

2 stops36h 17m

$822

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 12/16

2:59 pm-2:10 pm

2 stops16h 11m

Luxembourg

Tue 12/23

7:30 am-4:41 pm

2 stops16h 11m

$829

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 12/16

10:20 am-10:25 am

2 stops17h 05m

Luxembourg

Tue 12/23

7:30 am-4:52 pm

2 stops40h 22m

$832

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 12/16

11:35 am-6:00 pm

2 stops23h 25m

Luxembourg

Tue 12/23

2:30 pm-7:29 pm

2 stops35h 59m

$953

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 12/15

8:00 am-10:00 am

3 stops19h 00m

Luxembourg

Mon 12/22

6:55 am-6:05 pm

2 stops18h 10m

$1,104

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 12/16

11:35 am-6:00 pm

3 stops23h 25m

Luxembourg

Tue 12/23

5:00 pm-7:29 pm

3 stops33h 29m

$1,150

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 12/15

8:00 am-4:50 pm

3 stops25h 50m

Luxembourg

Mon 12/22

7:05 am-11:30 pm

3 stops23h 25m

$1,359

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Tue 12/16

11:35 am-10:00 am

3 stops15h 25m

Luxembourg

Tue 12/23

9:30 am-9:40 pm

2 stops19h 10m

$1,552

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Luxembourg from

How to get the cheapest flight ticket from Des Moines to Luxembourg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Luxembourg?

United Airlines and Air Canada are the most popular carriers operating from Des Moines to Luxembourg

When to book flights from Des Moines to Luxembourg

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Luxembourg according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Luxembourg (DSM to LUX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Luxembourg

Direct flights

None
There are no direct flights from Des Moines to Luxembourg. There are no popular flight routes from Des Moines to Luxembourg.
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  • How far is Des Moines to Luxembourg by plane?

    The distance between Des Moines and Luxembourg is about 4484.5 mi. Flights usually cover this in 15h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Luxembourg Airport?

    Prices for flights from Des Moines Airport to Luxembourg Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Luxembourg Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Luxembourg Airport.

  • What documentation or ID do you need to fly to Luxembourg Airport?

    The necessary travel and health documents for your Luxembourg Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette
Clervaux

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Luxembourg?

It is quick and easy to find Des Moines to Luxembourg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Luxembourg that suits you.

Can I find flights from Des Moines to Luxembourg with flexible booking policies on momondo?

Flights from Des Moines to Luxembourg with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Luxembourg?

momondo helps you find the best flight between Des Moines and Luxembourg by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Luxembourg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Luxembourg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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