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Cheap flights from Des Moines to Luxembourg from $642

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Luxembourg departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Des Moines to Luxembourg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
11:40 am - 4:10 pm
DSM
-
LUX
21h 30m
2 stops
Lufthansa Logo
9:40 am - 9:23 pm
LUX
-
DSM
18h 43m
2 stops
$866Lufthansa
Thu, May 7 - Thu, May 14
Lufthansa Logo
11:40 am - 4:10 pm
DSM
-
LUX
21h 30m
2 stops
Lufthansa Logo
9:40 am - 9:23 pm
LUX
-
DSM
18h 43m
2 stops
$870Lufthansa
Thu, May 7 - Thu, May 14
KLM Logo
2:33 pm - 2:05 pm
DSM
-
LUX
40h 32m
2 stops
KLM Logo
2:35 pm - 4:48 pm
LUX
-
DSM
33h 13m
2 stops
$874KLM
Mon, May 11 - Mon, May 18
Lufthansa Logo
7:05 pm - 4:10 pm
DSM
-
LUX
14h 05m
2 stops
Lufthansa Logo
2:30 pm - 9:23 pm
LUX
-
DSM
37h 53m
2 stops
$880Lufthansa
Thu, May 7 - Thu, May 14
American Airlines Logo
8:56 am - 10:35 am
DSM
-
LUX
18h 39m
3 stops
American Airlines Logo
9:05 pm - 7:33 pm
LUX
-
DSM
29h 28m
2 stops
$885American Airlines
Mon, May 11 - Mon, May 18
American Airlines Logo
8:56 am - 10:35 am
DSM
-
LUX
18h 39m
3 stops
American Airlines Logo
9:05 pm - 7:33 pm
LUX
-
DSM
29h 28m
2 stops
$886American Airlines
Mon, May 11 - Mon, May 18
British Airways Logo
8:03 pm - 10:40 am
DSM
-
LUX
31h 37m
2 stops
British Airways Logo
9:05 pm - 7:33 pm
LUX
-
DSM
29h 28m
2 stops
$902British Airways
Mon, May 11 - Mon, May 18
Multiple Airlines Logo
5:28 pm - 1:50 pm
DSM
-
LUX
13h 22m
2 stops
Multiple Airlines Logo
6:00 am - 4:48 pm
LUX
-
DSM
17h 48m
2 stops
$926Multiple Airlines
Sun, May 10 - Sun, May 17
Multiple Airlines Logo
5:28 pm - 1:50 pm
DSM
-
LUX
13h 22m
2 stops
Multiple Airlines Logo
6:00 am - 4:48 pm
LUX
-
DSM
17h 48m
2 stops
$932Multiple Airlines
Sun, May 10 - Sun, May 17
Multiple Airlines Logo
5:28 pm - 1:50 pm
DSM
-
LUX
13h 22m
2 stops
Multiple Airlines Logo
10:30 am - 8:36 pm
LUX
-
DSM
17h 06m
2 stops
$936Multiple Airlines
Sun, May 10 - Sun, May 17

Delta flights from Des Moines to Luxembourg

Our best Delta deals on Des Moines to Luxembourg flight tickets
Delta
Jun 14
DSM6:39 pmDes Moines
16h 16m
2 stops
LUX5:55 pmLuxembourg
Jul 1
LUX6:00 amLuxembourg
20h 38m
2 stops
DSM7:38 pmDes Moines
$1,167
Delta
Jun 13
DSM4:47 pmDes Moines
42h 08m
2 stops
LUX5:55 pmLuxembourg
Jul 1
LUX10:25 amLuxembourg
43h 06m
2 stops
DSM10:31 pmDes Moines
$1,174
Delta
Jun 14
DSM5:34 pmDes Moines
17h 21m
2 stops
LUX5:55 pmLuxembourg
Jun 29
LUX6:00 amLuxembourg
17h 54m
2 stops
DSM4:54 pmDes Moines
$1,237

United Airlines flights from Des Moines to Luxembourg

Our best United Airlines deals on Des Moines to Luxembourg flight tickets
United Airlines
Jun 18
DSM5:50 amDes Moines
30h 40m
2 stops
LUX7:30 pmLuxembourg
Jul 2
LUX8:20 amLuxembourg
44h 20m
2 stops
DSM9:40 pmDes Moines
$1,264
United Airlines
Jun 15
DSM11:34 amDes Moines
24h 56m
2 stops
LUX7:30 pmLuxembourg
Jul 3
LUX8:20 amLuxembourg
35h 10m
2 stops
DSM12:30 pmDes Moines
$1,300
United Airlines
Jun 14
DSM6:00 amDes Moines
27h 15m
2 stops
LUX4:15 pmLuxembourg
Jul 3
LUX8:20 amLuxembourg
35h 10m
2 stops
DSM12:30 pmDes Moines
$1,306

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 5/7

11:40 am-4:10 pm

2 stops21h 30m

Luxembourg

Thu 5/14

9:40 am-9:23 pm

2 stops18h 43m

$866

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 5/7

11:40 am-4:10 pm

2 stops21h 30m

Luxembourg

Thu 5/14

9:40 am-9:23 pm

2 stops18h 43m

$870

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 5/11

2:33 pm-2:05 pm

2 stops40h 32m

Luxembourg

Mon 5/18

2:35 pm-4:48 pm

2 stops33h 13m

$874

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 5/7

7:05 pm-4:10 pm

2 stops14h 05m

Luxembourg

Thu 5/14

2:30 pm-9:23 pm

2 stops37h 53m

$880

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 5/11

8:56 am-10:35 am

3 stops18h 39m

Luxembourg

Mon 5/18

9:05 pm-7:33 pm

2 stops29h 28m

$885

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 5/11

8:56 am-10:35 am

3 stops18h 39m

Luxembourg

Mon 5/18

9:05 pm-7:33 pm

2 stops29h 28m

$886

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Mon 5/11

8:03 pm-10:40 am

2 stops31h 37m

Luxembourg

Mon 5/18

9:05 pm-7:33 pm

2 stops29h 28m

$902

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 5/10

5:28 pm-1:50 pm

2 stops13h 22m

Luxembourg

Sun 5/17

6:00 am-4:48 pm

2 stops17h 48m

$926

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 5/10

5:28 pm-1:50 pm

2 stops13h 22m

Luxembourg

Sun 5/17

6:00 am-4:48 pm

2 stops17h 48m

$932
Quickest round-trip

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sun 5/10

5:28 pm-1:50 pm

2 stops13h 22m

Luxembourg

Sun 5/17

10:30 am-8:36 pm

2 stops17h 06m

$936

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

See travel insights to Luxembourg from

How to get the cheapest flight ticket from Des Moines to Luxembourg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Luxembourg?

Air Canada is the most popular carrier operating from Des Moines to Luxembourg

When to book flights from Des Moines to Luxembourg

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Luxembourg according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Luxembourg (DSM to LUX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Luxembourg

Fastest flight time

34h 30m

Direct flights

None
The fastest flight from Des Moines to Luxembourg takes 34h 30m
There are no direct flights from Des Moines to Luxembourg. There are no popular flight routes from Des Moines to Luxembourg.
Search flight deals

  • How far is Des Moines to Luxembourg by plane?

    The distance between Des Moines and Luxembourg is about 4484.5 mi. Flights usually cover this in 34h 30m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Luxembourg Airport?

    Prices for flights from Des Moines Airport to Luxembourg Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Luxembourg Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Luxembourg Airport.

  • What documentation or ID do you need to fly to Luxembourg Airport?

    The necessary travel and health documents for your Luxembourg Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette
Clervaux

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Luxembourg?

It is quick and easy to find Des Moines to Luxembourg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Luxembourg that suits you.

Can I find flights from Des Moines to Luxembourg with flexible booking policies on momondo?

Flights from Des Moines to Luxembourg with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Luxembourg?

momondo helps you find the best flight between Des Moines and Luxembourg by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Luxembourg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Luxembourg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Find better results for your trip to Luxembourg

Cabin classes currently available on flights to Luxembourg

List of cabin classes available on flights landing in Luxembourg. Availability may vary depending on flight origin and airline.
First Class to Luxembourg
Business Class to Luxembourg