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Cheap flights from Des Moines to Luxembourg from $411

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Luxembourg departing on 1/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Luxembourg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
11:30 am - 1:35 pm
DSM
-
LUX
19h 05m2 stops
Lufthansa Logo
10:35 am - 9:50 pm
LUX
-
DSM
18h 15m2 stops
$476Lufthansa
Fri, Jan 30 - Fri, Feb 6
Multiple Airlines Logo
5:16 pm - 9:55 pm
DSM
-
LUX
21h 39m2 stops
Multiple Airlines Logo
6:00 am - 8:54 pm
LUX
-
DSM
21h 54m2 stops
$478Multiple Airlines
Fri, Jan 30 - Fri, Feb 6
American Airlines Logo
5:21 am - 10:30 am
DSM
-
LUX
22h 09m2 stops
American Airlines Logo
11:00 am - 11:58 pm
LUX
-
DSM
19h 58m2 stops
$479American Airlines
Fri, Jan 30 - Fri, Feb 6
Lufthansa Logo
11:30 am - 10:15 am
DSM
-
LUX
15h 45m2 stops
Lufthansa Logo
7:10 am - 9:50 pm
LUX
-
DSM
21h 40m2 stops
$485Lufthansa
Fri, Feb 6 - Tue, Feb 10
American Airlines Logo
5:21 am - 10:30 am
DSM
-
LUX
22h 09m2 stops
American Airlines Logo
11:00 am - 11:08 pm
LUX
-
DSM
19h 08m2 stops
$488American Airlines
Fri, Jan 30 - Fri, Feb 6
Lufthansa Logo
11:30 am - 10:15 am
DSM
-
LUX
15h 45m2 stops
Lufthansa Logo
10:35 am - 9:50 pm
LUX
-
DSM
18h 15m2 stops
$491Lufthansa
Fri, Jan 30 - Fri, Feb 6
American Airlines Logo
6:00 am - 10:30 am
DSM
-
LUX
21h 30m3 stops
American Airlines Logo
9:55 pm - 9:07 pm
LUX
-
DSM
30h 12m2 stops
$492American Airlines
Fri, Feb 6 - Tue, Feb 10
American Airlines Logo
7:43 am - 10:30 am
DSM
-
LUX
19h 47m3 stops
American Airlines Logo
11:00 am - 11:08 pm
LUX
-
DSM
19h 08m2 stops
$493American Airlines
Fri, Jan 30 - Fri, Feb 6
Multiple Airlines Logo
11:30 am - 10:15 am
DSM
-
LUX
15h 45m2 stops
Multiple Airlines Logo
10:35 am - 2:33 pm
LUX
-
DSM
34h 58m3 stops
$498Multiple Airlines
Fri, Jan 30 - Fri, Feb 6
American Airlines Logo
7:43 am - 10:30 am
DSM
-
LUX
19h 47m3 stops
American Airlines Logo
11:00 am - 11:08 pm
LUX
-
DSM
19h 08m3 stops
$518American Airlines
Fri, Jan 30 - Fri, Feb 6

Lufthansa flights from Des Moines to Luxembourg

Our best Lufthansa deals on Des Moines to Luxembourg flight tickets
Lufthansa
Jan 30
DSM11:30 amDes Moines
19h 05m
2 stops
LUX1:35 pmLuxembourg
Feb 6
LUX10:35 amLuxembourg
18h 15m
2 stops
DSM9:50 pmDes Moines
$476
Find similar
Lufthansa
Feb 6
DSM11:30 amDes Moines
15h 45m
2 stops
LUX10:15 amLuxembourg
Feb 10
LUX7:10 amLuxembourg
21h 40m
2 stops
DSM9:50 pmDes Moines
$485
Find similar
Lufthansa
Jan 30
DSM11:30 amDes Moines
15h 45m
2 stops
LUX10:15 amLuxembourg
Feb 6
LUX10:35 amLuxembourg
18h 15m
2 stops
DSM9:50 pmDes Moines
$491
Find similar

American Airlines flights from Des Moines to Luxembourg

Our best American Airlines deals on Des Moines to Luxembourg flight tickets
American Airlines
Jan 30
DSM5:21 amDes Moines
22h 09m
2 stops
LUX10:30 amLuxembourg
Feb 6
LUX11:00 amLuxembourg
19h 58m
2 stops
DSM11:58 pmDes Moines
$479
Find similar
American Airlines
Jan 30
DSM5:21 amDes Moines
22h 09m
2 stops
LUX10:30 amLuxembourg
Feb 6
LUX11:00 amLuxembourg
19h 08m
2 stops
DSM11:08 pmDes Moines
$488
Find similar
American Airlines
Feb 6
DSM6:00 amDes Moines
21h 30m
3 stops
LUX10:30 amLuxembourg
Feb 10
LUX9:55 pmLuxembourg
30h 12m
2 stops
DSM9:07 pmDes Moines
$492
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

11:30 am-1:35 pm

2 stops19h 05m

Luxembourg

Fri 2/6

10:35 am-9:50 pm

2 stops18h 15m

$476

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

5:16 pm-9:55 pm

2 stops21h 39m

Luxembourg

Fri 2/6

6:00 am-8:54 pm

2 stops21h 54m

$478

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

5:21 am-10:30 am

2 stops22h 09m

Luxembourg

Fri 2/6

11:00 am-11:58 pm

2 stops19h 58m

$479

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 2/6

11:30 am-10:15 am

2 stops15h 45m

Luxembourg

Tue 2/10

7:10 am-9:50 pm

2 stops21h 40m

$485

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

5:21 am-10:30 am

2 stops22h 09m

Luxembourg

Fri 2/6

11:00 am-11:08 pm

2 stops19h 08m

$488

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

11:30 am-10:15 am

2 stops15h 45m

Luxembourg

Fri 2/6

10:35 am-9:50 pm

2 stops18h 15m

$491

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 2/6

6:00 am-10:30 am

3 stops21h 30m

Luxembourg

Tue 2/10

9:55 pm-9:07 pm

2 stops30h 12m

$492

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

7:43 am-10:30 am

3 stops19h 47m

Luxembourg

Fri 2/6

11:00 am-11:08 pm

2 stops19h 08m

$493

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

11:30 am-10:15 am

2 stops15h 45m

Luxembourg

Fri 2/6

10:35 am-2:33 pm

3 stops34h 58m

$498

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 1/30

7:43 am-10:30 am

3 stops19h 47m

Luxembourg

Fri 2/6

11:00 am-11:08 pm

3 stops19h 08m

$518

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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2

See travel insights to Luxembourg from

How to get the cheapest flight ticket from Des Moines to Luxembourg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Luxembourg?

American Airlines and Air Canada are the most popular carriers operating from Des Moines to Luxembourg

When to book flights from Des Moines to Luxembourg

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Luxembourg according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Luxembourg (DSM to LUX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Luxembourg

Fastest flight time

19h 05m

Direct flights

None
The fastest flight from Des Moines to Luxembourg takes 19h 05m
There are no direct flights from Des Moines to Luxembourg. There are no popular flight routes from Des Moines to Luxembourg.
Search flight deals

  • How far is Des Moines to Luxembourg by plane?

    The distance between Des Moines and Luxembourg is about 4484.5 mi. Flights usually cover this in 19h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Luxembourg Airport?

    Prices for flights from Des Moines Airport to Luxembourg Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Luxembourg Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Luxembourg Airport.

  • What documentation or ID do you need to fly to Luxembourg Airport?

    The necessary travel and health documents for your Luxembourg Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette
Clervaux

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Luxembourg?

It is quick and easy to find Des Moines to Luxembourg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Luxembourg that suits you.

Can I find flights from Des Moines to Luxembourg with flexible booking policies on momondo?

Flights from Des Moines to Luxembourg with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Luxembourg?

momondo helps you find the best flight between Des Moines and Luxembourg by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Luxembourg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Luxembourg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Find better results for your trip to Luxembourg

Cabin classes currently available on flights to Luxembourg

List of cabin classes available on flights landing in Luxembourg. Availability may vary depending on flight origin and airline.
First Class to Luxembourg
Business Class to Luxembourg