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Cheap flights from Des Moines to Luxembourg from $485

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Luxembourg departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Luxembourg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Air France Logo
10:51 am - 10:35 am
DSM
-
LUX
17h 44m
2 stops
Air France Logo
7:30 am - 4:54 pm
LUX
-
DSM
15h 24m
2 stops
$485Air France
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
1:52 pm - 9:10 pm
DSM
-
LUX
25h 18m
2 stops
American Airlines Logo
11:00 am - 11:40 pm
LUX
-
DSM
18h 40m
3 stops
$492American Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
1:52 pm - 4:50 pm
DSM
-
LUX
20h 58m
2 stops
American Airlines Logo
11:00 am - 11:40 pm
LUX
-
DSM
18h 40m
3 stops
$495American Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
10:51 am - 2:15 pm
DSM
-
LUX
21h 24m
2 stops
Multiple Airlines Logo
2:45 pm - 9:10 pm
LUX
-
DSM
36h 25m
2 stops
$614Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
British Airways Logo
1:38 pm - 10:30 am
DSM
-
LUX
37h 52m
2 stops
British Airways Logo
5:10 pm - 10:34 pm
LUX
-
DSM
35h 24m
2 stops
$692British Airways
Thu, Mar 5 - Mon, Mar 9
British Airways Logo
10:04 am - 10:30 am
DSM
-
LUX
41h 26m
2 stops
British Airways Logo
10:50 am - 11:40 pm
LUX
-
DSM
42h 50m
2 stops
$693British Airways
Thu, Mar 5 - Mon, Mar 9
Multiple Airlines Logo
5:47 pm - 2:15 pm
DSM
-
LUX
14h 28m
2 stops
Multiple Airlines Logo
2:45 pm - 9:10 pm
LUX
-
DSM
36h 25m
2 stops
$1,017Multiple Airlines
Fri, Mar 20 - Fri, Mar 27
Multiple Airlines Logo
5:47 pm - 2:15 pm
DSM
-
LUX
14h 28m
2 stops
Multiple Airlines Logo
2:45 pm - 9:10 pm
LUX
-
DSM
36h 25m
2 stops
$1,203Multiple Airlines
Fri, Mar 20 - Fri, Mar 27
Air Canada Logo
11:26 am - 10:15 am
DSM
-
LUX
16h 49m
3 stops
Air Canada Logo
8:10 am - 9:40 pm
LUX
-
DSM
19h 30m
3 stops
$1,257Air Canada
Fri, Mar 20 - Fri, Mar 27
Multiple Airlines Logo
11:33 am - 2:15 pm
DSM
-
LUX
20h 42m
2 stops
Multiple Airlines Logo
6:35 pm - 10:38 pm
LUX
-
DSM
34h 03m
2 stops
$1,508Multiple Airlines
Sat, Mar 21 - Sat, Mar 28

British Airways flights from Des Moines to Luxembourg

Our best British Airways deals on Des Moines to Luxembourg flight tickets
British Airways
Mar 5
DSM1:38 pmDes Moines
37h 52m
2 stops
LUX10:30 amLuxembourg
Mar 9
LUX5:10 pmLuxembourg
35h 24m
2 stops
DSM10:34 pmDes Moines
$692
British Airways
Mar 5
DSM10:04 amDes Moines
41h 26m
2 stops
LUX10:30 amLuxembourg
Mar 9
LUX10:50 amLuxembourg
42h 50m
2 stops
DSM11:40 pmDes Moines
$693
British Airways
Feb 5
DSM11:42 amDes Moines
26h 28m
2 stops
LUX9:10 pmLuxembourg
Feb 9
LUX5:10 pmLuxembourg
33h 52m
2 stops
DSM8:02 pmDes Moines
$990

Air Canada flights from Des Moines to Luxembourg

Our best Air Canada deals on Des Moines to Luxembourg flight tickets
Air Canada
Mar 20
DSM11:26 amDes Moines
16h 49m
3 stops
LUX10:15 amLuxembourg
Mar 27
LUX8:10 amLuxembourg
19h 30m
3 stops
DSM9:40 pmDes Moines
$1,257
Air Canada
Mar 21
DSM11:26 amDes Moines
16h 34m
3 stops
LUX10:00 amLuxembourg
Mar 28
LUX8:10 amLuxembourg
19h 30m
3 stops
DSM9:40 pmDes Moines
$3,698
Air Canada
Mar 21
DSM11:26 amDes Moines
16h 34m
3 stops
LUX10:00 amLuxembourg
Mar 28
LUX8:10 amLuxembourg
19h 30m
3 stops
DSM9:40 pmDes Moines
$3,706

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Wed 3/18

10:51 am-10:35 am

2 stops17h 44m

Luxembourg

Wed 3/25

7:30 am-4:54 pm

2 stops15h 24m

$485

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 3/19

1:52 pm-9:10 pm

2 stops25h 18m

Luxembourg

Thu 3/26

11:00 am-11:40 pm

3 stops18h 40m

$492

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Wed 3/18

1:52 pm-4:50 pm

2 stops20h 58m

Luxembourg

Wed 3/25

11:00 am-11:40 pm

3 stops18h 40m

$495

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 3/19

10:51 am-2:15 pm

2 stops21h 24m

Luxembourg

Thu 3/26

2:45 pm-9:10 pm

2 stops36h 25m

$614

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 3/5

1:38 pm-10:30 am

2 stops37h 52m

Luxembourg

Mon 3/9

5:10 pm-10:34 pm

2 stops35h 24m

$692

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Thu 3/5

10:04 am-10:30 am

2 stops41h 26m

Luxembourg

Mon 3/9

10:50 am-11:40 pm

2 stops42h 50m

$693

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 3/20

5:47 pm-2:15 pm

2 stops14h 28m

Luxembourg

Fri 3/27

2:45 pm-9:10 pm

2 stops36h 25m

$1,017

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 3/20

5:47 pm-2:15 pm

2 stops14h 28m

Luxembourg

Fri 3/27

2:45 pm-9:10 pm

2 stops36h 25m

$1,203

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Fri 3/20

11:26 am-10:15 am

3 stops16h 49m

Luxembourg

Fri 3/27

8:10 am-9:40 pm

3 stops19h 30m

$1,257

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

Sat 3/21

11:33 am-2:15 pm

2 stops20h 42m

Luxembourg

Sat 3/28

6:35 pm-10:38 pm

2 stops34h 03m

$1,508

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Luxembourg from

How to get the cheapest flight ticket from Des Moines to Luxembourg

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Luxembourg?

KLM and Air Canada are the most popular carriers operating from Des Moines to Luxembourg

When to book flights from Des Moines to Luxembourg

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Luxembourg according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Luxembourg (DSM to LUX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Luxembourg

Fastest flight time

26h 28m

Direct flights

None
The fastest flight from Des Moines to Luxembourg takes 26h 28m
There are no direct flights from Des Moines to Luxembourg. There are no popular flight routes from Des Moines to Luxembourg.
Search flight deals

  • How far is Des Moines to Luxembourg by plane?

    The distance between Des Moines and Luxembourg is about 4484.5 mi. Flights usually cover this in 26h 28m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Luxembourg Airport?

    Prices for flights from Des Moines Airport to Luxembourg Airport were last updated today.

  • How old do you have to be to fly from Des Moines Airport to Luxembourg Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Luxembourg Airport.

  • What documentation or ID do you need to fly to Luxembourg Airport?

    The necessary travel and health documents for your Luxembourg Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Luxembourg?

Book flights to Luxembourg if you plan to visit one of these locations
Esch-sur-Alzette
Clervaux

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Luxembourg?

It is quick and easy to find Des Moines to Luxembourg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Luxembourg that suits you.

Can I find flights from Des Moines to Luxembourg with flexible booking policies on momondo?

Flights from Des Moines to Luxembourg with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Luxembourg?

momondo helps you find the best flight between Des Moines and Luxembourg by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Luxembourg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Luxembourg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Find better results for your trip to Luxembourg

Cabin classes currently available on flights to Luxembourg

List of cabin classes available on flights landing in Luxembourg. Availability may vary depending on flight origin and airline.
First Class to Luxembourg
Business Class to Luxembourg