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Cheap flights from Des Moines to Indianapolis from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Indianapolis departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:55 am - 11:35 am
DSM
-
IND
3h 40m
1 stop
Delta Logo
7:05 am - 10:09 am
IND
-
DSM
4h 04m
1 stop
$251Delta
Wed, Mar 25 - Wed, Apr 1
Southwest Logo
5:30 am - 5:15 pm
DSM
-
IND
10h 45m
2 stops
Southwest Logo
4:55 pm - 10:05 pm
IND
-
DSM
6h 10m
1 stop
$256Southwest
Wed, Mar 25 - Wed, Apr 1
Delta Logo
10:34 am - 5:18 pm
DSM
-
IND
5h 44m
1 stop
Delta Logo
7:05 am - 10:18 am
IND
-
DSM
4h 13m
1 stop
$289Delta
Tue, Apr 28 - Sun, May 3
Southwest Logo
5:30 am - 12:40 pm
DSM
-
IND
6h 10m
2 stops
Southwest Logo
5:45 pm - 11:20 pm
IND
-
DSM
6h 35m
1 stop
$300Southwest
Tue, Apr 28 - Sun, May 3
Delta Logo
5:28 pm - 11:12 pm
DSM
-
IND
4h 44m
1 stop
Delta Logo
7:00 am - 10:16 am
IND
-
DSM
4h 16m
1 stop
$302Delta
Thu, May 7 - Sun, May 10
Southwest Logo
5:30 am - 12:40 pm
DSM
-
IND
6h 10m
2 stops
Southwest Logo
4:45 pm - 11:20 pm
IND
-
DSM
7h 35m
2 stops
$309Southwest
Tue, Apr 28 - Sun, May 3
Southwest Logo
3:40 pm - 11:15 pm
DSM
-
IND
6h 35m
2 stops
Southwest Logo
9:30 am - 10:05 pm
IND
-
DSM
13h 35m
2 stops
$310Southwest
Wed, Mar 25 - Wed, Apr 1
United Airlines Logo
8:00 am - 3:06 pm
DSM
-
IND
6h 06m
1 stop
United Airlines Logo
3:47 pm - 9:41 pm
IND
-
DSM
6h 54m
1 stop
$312United Airlines
Fri, Mar 6 - Mon, Mar 9
American Airlines Logo
5:00 am - 3:17 pm
DSM
-
IND
9h 17m
1 stop
American Airlines Logo
5:49 am - 10:54 am
IND
-
DSM
6h 05m
1 stop
$319American Airlines
Sat, Mar 7 - Sat, Mar 14
Delta Logo
5:57 pm - 11:59 pm
DSM
-
IND
5h 02m
1 stop
Delta Logo
7:00 am - 10:16 am
IND
-
DSM
4h 16m
1 stop
$327Delta
Fri, May 8 - Sun, May 10

United Airlines flights from Des Moines to Indianapolis

Our best United Airlines deals on Des Moines to Indianapolis flight tickets
United Airlines
Mar 6
DSM8:00 amDes Moines
6h 06m
1 stop
IND3:06 pmIndianapolis
Mar 9
IND3:47 pmIndianapolis
6h 54m
1 stop
DSM9:41 pmDes Moines
$312
United Airlines
Jun 11
DSM1:05 pmDes Moines
4h 56m
1 stop
IND7:01 pmIndianapolis
Jun 15
IND7:59 pmIndianapolis
5h 31m
1 stop
DSM12:30 amDes Moines
$387
United Airlines
Feb 23
DSM6:55 pmDes Moines
3h 49m
1 stop
IND11:44 pmIndianapolis
Feb 27
IND6:10 pmIndianapolis
4h 31m
1 stop
DSM9:41 pmDes Moines
$407

Delta flights from Des Moines to Indianapolis

Our best Delta deals on Des Moines to Indianapolis flight tickets
Delta
Mar 25
DSM6:55 amDes Moines
3h 40m
1 stop
IND11:35 amIndianapolis
Apr 1
IND7:05 amIndianapolis
4h 04m
1 stop
DSM10:09 amDes Moines
$251
Delta
Apr 28
DSM10:34 amDes Moines
5h 44m
1 stop
IND5:18 pmIndianapolis
May 3
IND7:05 amIndianapolis
4h 13m
1 stop
DSM10:18 amDes Moines
$289
Delta
May 7
DSM5:28 pmDes Moines
4h 44m
1 stop
IND11:12 pmIndianapolis
May 10
IND7:00 amIndianapolis
4h 16m
1 stop
DSM10:16 amDes Moines
$302

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 3/25

6:55 am-11:35 am

1 stop3h 40m

Indianapolis

Wed 4/1

7:05 am-10:09 am

1 stop4h 04m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 3/25

5:30 am-5:15 pm

2 stops10h 45m

Indianapolis

Wed 4/1

4:55 pm-10:05 pm

1 stop6h 10m

$256

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/28

10:34 am-5:18 pm

1 stop5h 44m

Indianapolis

Sun 5/3

7:05 am-10:18 am

1 stop4h 13m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/28

5:30 am-12:40 pm

2 stops6h 10m

Indianapolis

Sun 5/3

5:45 pm-11:20 pm

1 stop6h 35m

$300

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 5/7

5:28 pm-11:12 pm

1 stop4h 44m

Indianapolis

Sun 5/10

7:00 am-10:16 am

1 stop4h 16m

$302

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/28

5:30 am-12:40 pm

2 stops6h 10m

Indianapolis

Sun 5/3

4:45 pm-11:20 pm

2 stops7h 35m

$309

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 3/25

3:40 pm-11:15 pm

2 stops6h 35m

Indianapolis

Wed 4/1

9:30 am-10:05 pm

2 stops13h 35m

$310

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 3/6

8:00 am-3:06 pm

1 stop6h 06m

Indianapolis

Mon 3/9

3:47 pm-9:41 pm

1 stop6h 54m

$312

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 3/7

5:00 am-3:17 pm

1 stop9h 17m

Indianapolis

Sat 3/14

5:49 am-10:54 am

1 stop6h 05m

$319

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 5/8

5:57 pm-11:59 pm

1 stop5h 02m

Indianapolis

Sun 5/10

7:00 am-10:16 am

1 stop4h 16m

$327

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Des Moines to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, September is the cheapest month to fly from Des Moines to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Indianapolis during the month of September, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $259.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Saturday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $994. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Wednesday is $1,408.

Can stopping save me money on Des Moines to Indianapolis flights?

You could potentially save up to 52% on your flight if you consider stops on a Des Moines to Indianapolis flight.

How have Des Moines to Indianapolis flight prices changed over time?

When to book flights from Des Moines to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Indianapolis (DSM to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indianapolis

Fastest flight time

3h 49m

Direct flights

None
The fastest flight from Des Moines to Indianapolis takes 3h 49m
There are no direct flights from Des Moines to Indianapolis. There are no popular flight routes from Des Moines to Indianapolis.
Search flight deals

  • How far is Des Moines to Indianapolis by plane?

    There are 410.6 mi between Des Moines and Indianapolis. 3h 49m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Indianapolis Airport?

    Prices for flights from Des Moines Airport to Indianapolis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Indianapolis Airport?

  • How old do you have to be to fly from Des Moines Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Indianapolis?

Best airlines flying from Des Moines to Indianapolis

Compare and see reviews for airlines that fly from Des Moines to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $179Free CancellationRating
7.9
8,179 reviews
Search Delta flights
United AirlinesPriceFrom $196Free CancellationRating
7.4
9,276 reviews
Search United Airlines flights
American AirlinesPriceFrom $196Free CancellationRating
7.2
11,267 reviews
Search American Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
Franklin
West Lafayette
Seymour
Brownsburg
Speedway
Crawfordsville
Westfield
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indianapolis?

Finding the right flight to Indianapolis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Indianapolis quick and easy, saving you time and money.

Can I find flights from Des Moines to Indianapolis with flexible booking policies on momondo?

All flight searches from Des Moines to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from Des Moines.

I’m not ready to book a flight from Des Moines to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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