What is the cheapest airline that flies from Des Moines to Indianapolis?

Delta is the most popular carrier operating from Des Moines to Indianapolis

What airlines fly to Indianapolis?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Indianapolis from Des Moines according to our data. United Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Indianapolis. Keep in mind that there are 3 different airlines that fly to Indianapolis on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Indianapolis Airport?

Prices for flights from Des Moines Airport to Indianapolis Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport to Indianapolis Airport?

The number of operators available for flights from Des Moines Airport to Indianapolis Airport is 3 as of November 2025.

How old do you have to be to fly from Des Moines Airport to Indianapolis Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Indianapolis Airport.

What documentation or ID do you need to fly to Indianapolis Airport?

The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$126 Cheap Flights from Des Moines to Indianapolis in 2025/26

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Find the cheapest flights from Des Moines to Indianapolis

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:17 am - 11:29 amDSM-IND

4h 12m1 stop

12:09 pm - 4:58 pmIND-DSM

5h 49m1 stop

$251Delta

Find Deal

Tue, Dec 2 - Sat, Dec 6

7:40 am - 4:27 pmDSM-IND

7h 47m1 stop

3:45 pm - 6:34 pmIND-DSM

3h 49m1 stop

$275American Airlines

Find Deal

Wed, Feb 11 - Sun, Feb 15

11:09 am - 9:43 amDSM-IND

21h 34m2 stops

10:38 am - 10:09 pmIND-DSM

12h 31m2 stops

$281Multiple Airlines

Find Deal

Fri, Jan 9 - Sun, Jan 11

6:15 am - 11:29 amDSM-IND

4h 14m1 stop

7:50 am - 11:24 amIND-DSM

4h 34m1 stop

$289Delta

Find Deal

Thu, Jan 1 - Thu, Jan 8

4:32 pm - 12:17 pmDSM-IND

18h 45m1 stop

3:15 pm - 10:46 pmIND-DSM

8h 31m1 stop

$294Allegiant Air

Find Deal

Fri, Dec 12 - Sun, Dec 14

8:00 am - 8:47 amDSM-IND

23h 47m2 stops

9:29 pm - 2:06 pmIND-DSM

17h 37m1 stop

$296Multiple Airlines

Find Deal

Mon, Nov 24 - Wed, Nov 26

6:17 am - 11:29 amDSM-IND

4h 12m1 stop

6:22 am - 9:40 amIND-DSM

4h 18m1 stop

$299Delta

Find Deal

Tue, Dec 9 - Sun, Dec 14

6:10 am - 3:05 pmDSM-IND

7h 55m2 stops

3:10 pm - 9:20 pmIND-DSM

7h 10m1 stop

$300Southwest

Find Deal

Wed, Feb 11 - Sun, Feb 15

11:09 am - 9:43 amDSM-IND

21h 34m2 stops

2:31 pm - 11:07 pmIND-DSM

9h 36m1 stop

$305Multiple Airlines

Find Deal

Fri, Jan 9 - Sun, Jan 11

6:40 am - 5:12 pmDSM-IND

9h 32m1 stop

9:29 pm - 2:06 pmIND-DSM

17h 37m1 stop

$306Multiple Airlines

Find Deal

Mon, Nov 24 - Wed, Nov 26

Delta flights from Des Moines to Indianapolis

Our best Delta deals on Des Moines to Indianapolis flight tickets

Delta

Dec 2

DSM6:17 amDes Moines

4h 12m

1 stop

IND11:29 amIndianapolis

Dec 6

IND12:09 pmIndianapolis

5h 49m

1 stop

DSM4:58 pmDes Moines

$251

Find similar

Delta

Jan 1

DSM6:15 amDes Moines

4h 14m

1 stop

IND11:29 amIndianapolis

Jan 8

IND7:05 amIndianapolis

4h 14m

1 stop

DSM10:19 amDes Moines

$289

Find similar

Delta

Dec 9

DSM6:17 amDes Moines

4h 12m

1 stop

IND11:29 amIndianapolis

Dec 14

IND6:22 amIndianapolis

4h 18m

1 stop

DSM9:40 amDes Moines

$299

Find similar

American Airlines flights from Des Moines to Indianapolis

Our best American Airlines deals on Des Moines to Indianapolis flight tickets

American Airlines

Feb 11

DSM7:40 amDes Moines

7h 47m

1 stop

IND4:27 pmIndianapolis

Feb 15

IND3:45 pmIndianapolis

3h 49m

1 stop

DSM6:34 pmDes Moines

$275

Find similar

American Airlines

Dec 18

DSM3:55 pmDes Moines

4h 02m

1 stop

IND8:57 pmIndianapolis

Dec 23

IND8:11 pmIndianapolis

5h 26m

1 stop

DSM12:37 amDes Moines

$317

Find similar

American Airlines

Jan 1

DSM6:40 amDes Moines

7h 47m

2 stops

IND3:27 pmIndianapolis

Jan 8

IND6:18 pmIndianapolis

3h 46m

1 stop

DSM9:04 pmDes Moines

$436

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 12/2

6:17 am-11:29 am

1 stop4h 12m

Indianapolis

Sat 12/6

12:09 pm-4:58 pm

1 stop5h 49m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 2/11

7:40 am-4:27 pm

1 stop7h 47m

Indianapolis

Sun 2/15

3:45 pm-6:34 pm

1 stop3h 49m

$275

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 1/9

11:09 am-9:43 am

2 stops21h 34m

Indianapolis

Sun 1/11

10:38 am-10:09 pm

2 stops12h 31m

$281

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 1/1

6:15 am-11:29 am

1 stop4h 14m

Indianapolis

Thu 1/8

7:50 am-11:24 am

1 stop4h 34m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 12/12

4:32 pm-12:17 pm

1 stop18h 45m

Indianapolis

Sun 12/14

3:15 pm-10:46 pm

1 stop8h 31m

$294

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 11/24

8:00 am-8:47 am

2 stops23h 47m

Indianapolis

Wed 11/26

9:29 pm-2:06 pm

1 stop17h 37m

$296

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 12/9

6:17 am-11:29 am

1 stop4h 12m

Indianapolis

Sun 12/14

6:22 am-9:40 am

1 stop4h 18m

$299

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 2/11

6:10 am-3:05 pm

2 stops7h 55m

Indianapolis

Sun 2/15

3:10 pm-9:20 pm

1 stop7h 10m

$300

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 1/9

11:09 am-9:43 am

2 stops21h 34m

Indianapolis

Sun 1/11

2:31 pm-11:07 pm

1 stop9h 36m

$305

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 11/24

6:40 am-5:12 pm

1 stop9h 32m

Indianapolis

Wed 11/26

9:29 pm-2:06 pm

1 stop17h 37m

$306

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Indianapolis?

In general, September is the cheapest month to fly from Des Moines to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Indianapolis during the month of September, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $259.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Monday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $479. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Wednesday is $1,408.

How have Des Moines to Indianapolis flight prices changed over time?

As of November 2025, prices for Des Moines to Indianapolis flights are approximately 19% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Indianapolis (DSM to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indianapolis

Direct flights	None

There are no direct flights from Des Moines to Indianapolis. There are no popular flight routes from Des Moines to Indianapolis.

Search flight deals

How far is Des Moines to Indianapolis by plane?
There are 410.6 mi between Des Moines and Indianapolis. 4h 02m is a normal flight duration for this route.
When did momondo last update prices for flights from Des Moines Airport to Indianapolis Airport?
Prices for flights from Des Moines Airport to Indianapolis Airport were last updated today.
How many operators does momondo search for flights from Des Moines Airport to Indianapolis Airport?
The number of operators available for flights from Des Moines Airport to Indianapolis Airport is 3 as of November 2025.
How old do you have to be to fly from Des Moines Airport to Indianapolis Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Indianapolis Airport.
What documentation or ID do you need to fly to Indianapolis Airport?
The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Des Moines to Indianapolis?
Based on momondo bookings for flights between Des Moines and Indianapolis, the leading airline is American Airlines, making up 37% of the total bookings. Other popular airlines include Delta with 34% and United Airlines with 29%.

Best airlines flying from Des Moines to Indianapolis

Compare and see reviews for airlines that fly from Des Moines to Indianapolis with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $196	Free Cancellation	Rating 7.9 8,003 reviews	Search Delta flights
American Airlines	PriceFrom $196	Free Cancellation	Rating 7.2 11,045 reviews	Search American Airlines flights
United Airlines	PriceFrom $210	Free Cancellation	Rating 7.4 9,019 reviews	Search United Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indianapolis?

Finding the right flight to Indianapolis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Indianapolis quick and easy, saving you time and money.

Can I find flights from Des Moines to Indianapolis with flexible booking policies on momondo?

All flight searches from Des Moines to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from Des Moines.

I’m not ready to book a flight from Des Moines to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.