Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Indianapolis from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Indianapolis departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:35 pm - 10:14 pmDSM-IND
5h 39m1 stop
United Airlines Logo
11:25 am - 2:33 pmIND-DSM
4h 08m1 stop
$175United Airlines
Find Deal
Tue, Jan 6 - Thu, Jan 8
Delta Logo
6:24 am - 11:30 amDSM-IND
4h 06m1 stop
Delta Logo
12:10 pm - 5:08 pmIND-DSM
5h 58m1 stop
$191Delta
Find Deal
Mon, Jan 26 - Thu, Jan 29
Southwest Logo
3:20 pm - 10:05 pmDSM-IND
5h 45m2 stops
Southwest Logo
2:05 pm - 7:15 pmIND-DSM
6h 10m1 stop
$209Southwest
Find Deal
Wed, Feb 18 - Sat, Feb 21
Multiple Airlines Logo
10:53 am - 11:33 amDSM-IND
23h 40m2 stops
Multiple Airlines Logo
3:01 pm - 10:46 pmIND-DSM
8h 45m1 stop
$231Multiple Airlines
Find Deal
Tue, Jan 6 - Thu, Jan 8
Delta Logo
6:50 am - 11:44 amDSM-IND
3h 54m1 stop
Delta Logo
7:00 am - 10:17 amIND-DSM
4h 17m1 stop
$251Delta
Find Deal
Wed, Feb 18 - Sat, Feb 21
Multiple Airlines Logo
6:14 pm - 1:41 pmDSM-IND
18h 27m1 stop
Multiple Airlines Logo
12:21 pm - 10:09 pmIND-DSM
34h 48m2 stops
$265Multiple Airlines
Find Deal
Wed, Jan 14 - Wed, Jan 21
Southwest Logo
6:10 am - 3:05 pmDSM-IND
7h 55m2 stops
Southwest Logo
11:25 am - 9:10 pmIND-DSM
10h 45m2 stops
$267Southwest
Find Deal
Tue, Jan 6 - Thu, Jan 8
Delta Logo
4:21 pm - 10:30 pmDSM-IND
5h 09m1 stop
Delta Logo
3:43 pm - 8:54 pmIND-DSM
6h 11m1 stop
$285Delta
Find Deal
Fri, Jan 16 - Mon, Jan 19
Multiple Airlines Logo
4:30 pm - 9:43 amDSM-IND
40h 13m2 stops
Multiple Airlines Logo
5:10 am - 10:46 pmIND-DSM
18h 36m1 stop
$297Multiple Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22
Multiple Airlines Logo
4:30 pm - 12:18 amDSM-IND
30h 48m2 stops
Multiple Airlines Logo
10:38 am - 10:09 pmIND-DSM
12h 31m2 stops
$319Multiple Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22

Southwest flights from Des Moines to Indianapolis

Our best Southwest deals on Des Moines to Indianapolis flight tickets
Southwest
Feb 18
DSM3:20 pmDes Moines
5h 45m
2 stops
IND10:05 pmIndianapolis
Feb 21
IND2:05 pmIndianapolis
6h 10m
1 stop
DSM7:15 pmDes Moines
$209
Find similar
Southwest
Jan 6
DSM6:10 amDes Moines
7h 55m
2 stops
IND3:05 pmIndianapolis
Jan 8
IND11:25 amIndianapolis
10h 45m
2 stops
DSM9:10 pmDes Moines
$267
Find similar
Southwest
Jan 16
DSM6:25 amDes Moines
12h 50m
2 stops
IND8:15 pmIndianapolis
Jan 19
IND12:45 pmIndianapolis
10h 30m
2 stops
DSM10:15 pmDes Moines
$459
Find similar

Delta flights from Des Moines to Indianapolis

Our best Delta deals on Des Moines to Indianapolis flight tickets
Delta
Jan 26
DSM6:24 amDes Moines
4h 06m
1 stop
IND11:30 amIndianapolis
Jan 29
IND12:10 pmIndianapolis
5h 58m
1 stop
DSM5:08 pmDes Moines
$191
Find similar
Delta
Jan 16
DSM4:21 pmDes Moines
5h 09m
1 stop
IND10:30 pmIndianapolis
Jan 19
IND3:43 pmIndianapolis
6h 11m
1 stop
DSM8:54 pmDes Moines
$285
Find similar
Delta
May 8
DSM5:35 pmDes Moines
4h 28m
1 stop
IND11:03 pmIndianapolis
May 10
IND6:05 amIndianapolis
4h 14m
1 stop
DSM9:19 amDes Moines
$327
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 1/6

3:35 pm-10:14 pm

1 stop5h 39m

Indianapolis

Thu 1/8

11:25 am-2:33 pm

1 stop4h 08m

$175

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Mon 1/26

6:24 am-11:30 am

1 stop4h 06m

Indianapolis

Thu 1/29

12:10 pm-5:08 pm

1 stop5h 58m

$191

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 2/18

3:20 pm-10:05 pm

2 stops5h 45m

Indianapolis

Sat 2/21

2:05 pm-7:15 pm

1 stop6h 10m

$209

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 1/6

10:53 am-11:33 am

2 stops23h 40m

Indianapolis

Thu 1/8

3:01 pm-10:46 pm

1 stop8h 45m

$231

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 2/18

6:50 am-11:44 am

1 stop3h 54m

Indianapolis

Sat 2/21

7:00 am-10:17 am

1 stop4h 17m

$251

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Wed 1/14

6:14 pm-1:41 pm

1 stop18h 27m

Indianapolis

Wed 1/21

12:21 pm-10:09 pm

2 stops34h 48m

$265

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 1/6

6:10 am-3:05 pm

2 stops7h 55m

Indianapolis

Thu 1/8

11:25 am-9:10 pm

2 stops10h 45m

$267

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Fri 1/16

4:21 pm-10:30 pm

1 stop5h 09m

Indianapolis

Mon 1/19

3:43 pm-8:54 pm

1 stop6h 11m

$285

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 1/15

4:30 pm-9:43 am

2 stops40h 13m

Indianapolis

Thu 1/22

5:10 am-10:46 pm

1 stop18h 36m

$297

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 1/15

4:30 pm-12:18 am

2 stops30h 48m

Indianapolis

Thu 1/22

10:38 am-10:09 pm

2 stops12h 31m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Indianapolis from

How to get the cheapest flight ticket from Des Moines to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, September is the cheapest month to fly from Des Moines to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Indianapolis during the month of September, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $259.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Monday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $479. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Wednesday is $1,408.

How have Des Moines to Indianapolis flight prices changed over time?

As of December 2025, prices for Des Moines to Indianapolis flights are approximately 67% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Indianapolis (DSM to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indianapolis

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from Des Moines to Indianapolis takes 4h 06m
There are no direct flights from Des Moines to Indianapolis. There are no popular flight routes from Des Moines to Indianapolis.
Search flight deals

  • How far is Des Moines to Indianapolis by plane?

    There are 410.6 mi between Des Moines and Indianapolis. 3h 42m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Indianapolis Airport?

    Prices for flights from Des Moines Airport to Indianapolis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Indianapolis Airport?

  • How old do you have to be to fly from Des Moines Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Indianapolis?

Best airlines flying from Des Moines to Indianapolis

Compare and see reviews for airlines that fly from Des Moines to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $196Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
United AirlinesPriceFrom $210Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Anderson
Plainfield
Greenwood
Noblesville
Fishers
Carmel
Shelbyville
West Lafayette
Seymour
Franklin
Speedway
Brownsburg
Crawfordsville
Greenfield
Westfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indianapolis?

Finding the right flight to Indianapolis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Indianapolis quick and easy, saving you time and money.

Can I find flights from Des Moines to Indianapolis with flexible booking policies on momondo?

All flight searches from Des Moines to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from Des Moines.

I’m not ready to book a flight from Des Moines to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Indianapolis trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 1/2
Fri 1/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States