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Cheap flights from Des Moines to Indianapolis from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Indianapolis departing on 5/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Indianapolis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
6:55 am - 1:15 pm
DSM
-
IND
5h 20m
1 stop
Southwest Logo
6:40 am - 11:25 am
IND
-
DSM
5h 45m
1 stop
$271Southwest
Tue, Apr 7 - Tue, Apr 14
American Airlines Logo
2:16 pm - 7:03 pm
DSM
-
IND
3h 47m
1 stop
American Airlines Logo
9:40 am - 1:46 pm
IND
-
DSM
5h 06m
1 stop
$273American Airlines
Sat, Apr 25 - Sat, May 2
Southwest Logo
6:55 am - 1:15 pm
DSM
-
IND
5h 20m
1 stop
Southwest Logo
3:40 pm - 10:10 pm
IND
-
DSM
7h 30m
2 stops
$276Southwest
Tue, Apr 7 - Tue, Apr 14
Southwest Logo
5:30 am - 12:40 pm
DSM
-
IND
6h 10m
2 stops
Southwest Logo
3:40 pm - 10:10 pm
IND
-
DSM
7h 30m
2 stops
$281Southwest
Tue, Apr 7 - Tue, Apr 14
American Airlines Logo
8:03 pm - 12:32 am
DSM
-
IND
3h 29m
1 stop
American Airlines Logo
9:40 am - 1:46 pm
IND
-
DSM
5h 06m
1 stop
$289American Airlines
Thu, Apr 23 - Thu, Apr 30
United Airlines Logo
1:10 pm - 5:48 pm
DSM
-
IND
3h 38m
1 stop
United Airlines Logo
9:00 am - 2:25 pm
IND
-
DSM
6h 25m
1 stop
$291United Airlines
Tue, Apr 14 - Thu, Apr 16
Southwest Logo
5:35 am - 12:05 pm
DSM
-
IND
5h 30m
2 stops
Southwest Logo
6:35 am - 11:30 am
IND
-
DSM
5h 55m
1 stop
$296Southwest
Sat, Apr 25 - Sat, May 2
Delta Logo
5:45 pm - 12:07 am
DSM
-
IND
5h 22m
1 stop
Delta Logo
5:58 pm - 8:49 pm
IND
-
DSM
3h 51m
1 stop
$299Delta
Tue, Apr 14 - Fri, Apr 17
Southwest Logo
5:30 am - 12:40 pm
DSM
-
IND
6h 10m
2 stops
Southwest Logo
6:35 pm - 11:05 pm
IND
-
DSM
5h 30m
2 stops
$301Southwest
Tue, Apr 14 - Thu, Apr 16
Southwest Logo
4:20 pm - 11:55 pm
DSM
-
IND
6h 35m
1 stop
Southwest Logo
2:15 pm - 11:05 pm
IND
-
DSM
9h 50m
2 stops
$302Southwest
Thu, Apr 23 - Thu, Apr 30

American Airlines flights from Des Moines to Indianapolis

Our best American Airlines deals on Des Moines to Indianapolis flight tickets
American Airlines
Apr 25
DSM2:16 pmDes Moines
3h 47m
1 stop
IND7:03 pmIndianapolis
May 2
IND9:40 amIndianapolis
5h 06m
1 stop
DSM1:46 pmDes Moines
$273
American Airlines
Apr 23
DSM8:03 pmDes Moines
3h 29m
1 stop
IND12:32 amIndianapolis
Apr 30
IND9:40 amIndianapolis
5h 06m
1 stop
DSM1:46 pmDes Moines
$289
American Airlines
Apr 14
DSM12:00 pmDes Moines
6h 03m
1 stop
IND7:03 pmIndianapolis
Apr 17
IND5:55 amIndianapolis
3h 31m
1 stop
DSM8:26 amDes Moines
$309

United Airlines flights from Des Moines to Indianapolis

Our best United Airlines deals on Des Moines to Indianapolis flight tickets
United Airlines
Apr 14
DSM1:10 pmDes Moines
3h 38m
1 stop
IND5:48 pmIndianapolis
Apr 16
IND9:00 amIndianapolis
6h 25m
1 stop
DSM2:25 pmDes Moines
$291
United Airlines
May 9
DSM11:40 amDes Moines
5h 12m
1 stop
IND5:52 pmIndianapolis
May 13
IND7:15 amIndianapolis
4h 22m
1 stop
DSM10:37 amDes Moines
$326
United Airlines
May 9
DSM8:00 amDes Moines
6h 03m
1 stop
IND3:03 pmIndianapolis
May 13
IND7:15 amIndianapolis
4h 22m
1 stop
DSM10:37 amDes Moines
$336

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Des Moines to Indianapolis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/7

6:55 am-1:15 pm

1 stop5h 20m

Indianapolis

Tue 4/14

6:40 am-11:25 am

1 stop5h 45m

$271

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 4/25

2:16 pm-7:03 pm

1 stop3h 47m

Indianapolis

Sat 5/2

9:40 am-1:46 pm

1 stop5h 06m

$273

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/7

6:55 am-1:15 pm

1 stop5h 20m

Indianapolis

Tue 4/14

3:40 pm-10:10 pm

2 stops7h 30m

$276

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/7

5:30 am-12:40 pm

2 stops6h 10m

Indianapolis

Tue 4/14

3:40 pm-10:10 pm

2 stops7h 30m

$281
Quickest round-trip

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 4/23

8:03 pm-12:32 am

1 stop3h 29m

Indianapolis

Thu 4/30

9:40 am-1:46 pm

1 stop5h 06m

$289

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/14

1:10 pm-5:48 pm

1 stop3h 38m

Indianapolis

Thu 4/16

9:00 am-2:25 pm

1 stop6h 25m

$291

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 4/25

5:35 am-12:05 pm

2 stops5h 30m

Indianapolis

Sat 5/2

6:35 am-11:30 am

1 stop5h 55m

$296

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/14

5:45 pm-12:07 am

1 stop5h 22m

Indianapolis

Fri 4/17

5:58 pm-8:49 pm

1 stop3h 51m

$299

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Tue 4/14

5:30 am-12:40 pm

2 stops6h 10m

Indianapolis

Thu 4/16

6:35 pm-11:05 pm

2 stops5h 30m

$301

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 4/23

4:20 pm-11:55 pm

1 stop6h 35m

Indianapolis

Thu 4/30

2:15 pm-11:05 pm

2 stops9h 50m

$302

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Indianapolis from

How to get the cheapest flight ticket from Des Moines to Indianapolis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Indianapolis?

In general, September is the cheapest month to fly from Des Moines to Indianapolis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $251. If you are unable to visit Indianapolis during the month of September, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $259.

What is the cheapest day to depart on your flight to Indianapolis?

Our data shows that Saturday is the least expensive day to fly to Indianapolis. Tickets to fly out on this day can be as low as $994. Be sure to avoid booking your departure on a Wednesday as prices are generally higher than usual. According to our data, the average ticket price to Indianapolis on Wednesday is $1,408.

Can stopping save me money on Des Moines to Indianapolis flights?

You could potentially save up to 30% on your flight if you consider stops on a Des Moines to Indianapolis flight.

How have Des Moines to Indianapolis flight prices changed over time?

When to book flights from Des Moines to Indianapolis

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Indianapolis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Indianapolis (DSM to IND) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Indianapolis

Fastest flight time

3h 50m

Direct flights

None
The fastest flight from Des Moines to Indianapolis takes 3h 50m
There are no direct flights from Des Moines to Indianapolis. There are no popular flight routes from Des Moines to Indianapolis.
Search flight deals

  • How far is Des Moines to Indianapolis by plane?

    There are 410.6 mi between Des Moines and Indianapolis. 3h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Indianapolis Airport?

    Prices for flights from Des Moines Airport to Indianapolis Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Indianapolis Airport?

  • How old do you have to be to fly from Des Moines Airport to Indianapolis Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Indianapolis Airport.

  • What documentation or ID do you need to fly to Indianapolis Airport?

    The travel and health documents required for your trip to Indianapolis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Indianapolis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Indianapolis?

Best airlines flying from Des Moines to Indianapolis

Compare and see reviews for airlines that fly from Des Moines to Indianapolis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,285 reviews
Search Delta flights
American AirlinesPriceFrom $196Free CancellationRating
7.1
11,446 reviews
Search American Airlines flights
United AirlinesPriceFrom $210Free CancellationRating
7.4
9,418 reviews
Search United Airlines flights

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Bloomington
Kokomo
Muncie
Plainfield
Anderson
Greenwood
Noblesville
Carmel
Fishers
Shelbyville
Franklin
West Lafayette
Seymour
Brownsburg
Speedway
Crawfordsville
Westfield
Greenfield
Mooresville

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Indianapolis?

Finding the right flight to Indianapolis from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Indianapolis quick and easy, saving you time and money.

Can I find flights from Des Moines to Indianapolis with flexible booking policies on momondo?

All flight searches from Des Moines to Indianapolis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Indianapolis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Indianapolis from Des Moines.

I’m not ready to book a flight from Des Moines to Indianapolis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Indianapolis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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