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Cheap flights from Des Moines to Chile from $397

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Chile departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Chile

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:31 pm - 8:00 amDSM-SCL
13h 29m1 stop
American Airlines Logo
10:30 pm - 11:29 pmSCL-DSM
27h 59m1 stop
$741American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
12:54 pm - 9:00 amDSM-SCL
17h 06m2 stops
American Airlines Logo
11:15 pm - 2:55 pmSCL-DSM
18h 40m1 stop
$746American Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
6:05 am - 8:50 amDSM-SCL
23h 45m1 stop
United Airlines Logo
10:45 pm - 2:20 pmSCL-DSM
18h 35m2 stops
$756United Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
LATAM Airlines Logo
5:35 am - 5:50 amDSM-SCL
21h 15m2 stops
LATAM Airlines Logo
4:35 am - 10:34 pmSCL-DSM
20h 59m2 stops
$760LATAM Airlines
Find Deal
Wed, Nov 26 - Tue, Dec 2
Delta Logo
5:35 am - 6:35 amDSM-SCL
22h 00m2 stops
Delta Logo
8:15 am - 10:34 pmSCL-DSM
17h 19m2 stops
$764Delta
Find Deal
Wed, Nov 26 - Wed, Dec 3
LATAM Airlines Logo
5:35 am - 5:50 amDSM-SCL
21h 15m2 stops
LATAM Airlines Logo
4:35 am - 10:34 pmSCL-DSM
20h 59m2 stops
$765LATAM Airlines
Find Deal
Wed, Nov 26 - Tue, Dec 2
United Airlines Logo
8:02 am - 8:50 amDSM-SCL
21h 48m2 stops
United Airlines Logo
10:45 pm - 2:12 pmSCL-DSM
18h 27m1 stop
$769United Airlines
Find Deal
Thu, Nov 27 - Thu, Dec 4
Multiple Airlines Logo
9:44 am - 4:17 amDSM-SCL
39h 33m3 stops
Multiple Airlines Logo
9:29 pm - 10:21 pmSCL-DSM
27h 52m3 stops
$862Multiple Airlines
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Wed, Nov 26 - Wed, Dec 3
Multiple Airlines Logo
9:44 am - 4:17 amDSM-SCL
39h 33m3 stops
Multiple Airlines Logo
6:00 am - 10:21 pmSCL-DSM
43h 21m3 stops
$877Multiple Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
Delta Logo
2:16 pm - 12:50 pmDSM-SCL
19h 34m2 stops
Delta Logo
5:25 pm - 10:38 amSCL-DSM
20h 13m2 stops
$910Delta
Find Deal
Mon, Dec 8 - Fri, Dec 12

LATAM Airlines flights from Des Moines to Chile

Our best LATAM Airlines deals on Des Moines to Chile flight tickets
LATAM Airlines
Nov 26
DSM5:35 amDes Moines
21h 15m
2 stops
SCL5:50 amSantiago Arturo Merino Benitez
Dec 2
SCL4:35 amSantiago Arturo Merino Benitez
20h 59m
2 stops
DSM10:34 pmDes Moines
$760
Find similar
LATAM Airlines
Nov 26
DSM5:35 amDes Moines
21h 15m
2 stops
SCL5:50 amSantiago Arturo Merino Benitez
Dec 2
SCL4:35 amSantiago Arturo Merino Benitez
20h 59m
2 stops
DSM10:34 pmDes Moines
$765
Find similar
LATAM Airlines
Nov 26
DSM5:35 amDes Moines
21h 50m
2 stops
SCL6:25 amSantiago Arturo Merino Benitez
Dec 2
SCL4:35 amSantiago Arturo Merino Benitez
20h 59m
2 stops
DSM10:34 pmDes Moines
$767
Find similar

American Airlines flights from Des Moines to Chile

Our best American Airlines deals on Des Moines to Chile flight tickets
American Airlines
Nov 26
DSM3:31 pmDes Moines
13h 29m
1 stop
SCL8:00 amSantiago Arturo Merino Benitez
Dec 3
SCL10:30 pmSantiago Arturo Merino Benitez
27h 59m
1 stop
DSM11:29 pmDes Moines
$741
Find similar
American Airlines
Nov 26
DSM12:54 pmDes Moines
17h 06m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Dec 3
SCL11:15 pmSantiago Arturo Merino Benitez
18h 40m
1 stop
DSM2:55 pmDes Moines
$746
Find similar
American Airlines
Nov 28
DSM6:00 amDes Moines
24h 00m
1 stop
SCL9:00 amSantiago Arturo Merino Benitez
Dec 5
SCL11:15 pmSantiago Arturo Merino Benitez
14h 14m
1 stop
DSM10:29 amDes Moines
$840
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Des Moines to Chile that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

3:31 pm-8:00 am

1 stop13h 29m

Santiago Arturo Merino Benitez

Wed 12/3

10:30 pm-11:29 pm

1 stop27h 59m

$741

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

12:54 pm-9:00 am

2 stops17h 06m

Santiago Arturo Merino Benitez

Wed 12/3

11:15 pm-2:55 pm

1 stop18h 40m

$746

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

6:05 am-8:50 am

1 stop23h 45m

Santiago Arturo Merino Benitez

Wed 12/3

10:45 pm-2:20 pm

2 stops18h 35m

$756

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

5:35 am-5:50 am

2 stops21h 15m

Santiago Arturo Merino Benitez

Tue 12/2

4:35 am-10:34 pm

2 stops20h 59m

$760

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

5:35 am-6:35 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Wed 12/3

8:15 am-10:34 pm

2 stops17h 19m

$764

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

5:35 am-5:50 am

2 stops21h 15m

Santiago Arturo Merino Benitez

Tue 12/2

4:35 am-10:34 pm

2 stops20h 59m

$765

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 11/27

8:02 am-8:50 am

2 stops21h 48m

Santiago Arturo Merino Benitez

Thu 12/4

10:45 pm-2:12 pm

1 stop18h 27m

$769

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

9:44 am-4:17 am

3 stops39h 33m

Santiago Arturo Merino Benitez

Wed 12/3

9:29 pm-10:21 pm

3 stops27h 52m

$862

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 11/26

9:44 am-4:17 am

3 stops39h 33m

Santiago Arturo Merino Benitez

Wed 12/3

6:00 am-10:21 pm

3 stops43h 21m

$877

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 12/8

2:16 pm-12:50 pm

2 stops19h 34m

Santiago Arturo Merino Benitez

Fri 12/12

5:25 pm-10:38 am

2 stops20h 13m

$910

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Chile from

How to get the cheapest flight ticket from Des Moines to Chile

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chile?

Our data shows that Tuesday is the least expensive day to fly to Chile. Tickets to fly out on this day can be as low as $958. On the other hand, Thursday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,692.

What is the cheapest time of day to depart on your flight to Chile?

According to our data, the cheapest time of day to fly to Chile is in the afternoon. momondo users have found flights departing from Des Moines to Chile in the afternoon for as low as $768. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $1,081 on average. Flights to Chile from Des Moines in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Des Moines to Chile flights?

You could potentially save up to 23% on your flight if you consider stops on a Des Moines to Chile flight.

Cheap Des Moines to Chile flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Chile

Direct flights

None
There are no direct flights from Des Moines to Chile. There are no popular flight routes from Des Moines to Chile.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Chile?

    Prices for flights from Des Moines Airport to Chile were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Chile?

  • How old do you have to be to fly from Des Moines Airport to Chile?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Chile.

  • What documentation or ID do you need to fly to Chile?

    The travel and health documents required for your trip to Chile can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chile. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Chile

Compare and see reviews for airlines that fly from Des Moines to Chile with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $814Free CancellationRating
7.5
1,866 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Chile?

Finding the right flight to Chile from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chile quick and easy, saving you time and money.

Can I find flights from Des Moines to Chile with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chile from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Chile?

momondo provides multiple filters to help you find the best flight to Chile from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Chile right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chile from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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