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Cheap flights from Columbia to Key West from $135

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia to Key West departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:45 pm - 7:40 pm
CAE
-
EYW
6h 55m1 stop
Delta Logo
7:10 am - 11:58 am
EYW
-
CAE
4h 48m1 stop
$269Delta
Wed, Jan 21 - Wed, Jan 28
American Airlines Logo
11:59 am - 6:01 pm
CAE
-
EYW
6h 02m1 stop
American Airlines Logo
4:37 pm - 10:59 pm
EYW
-
CAE
6h 22m2 stops
$274American Airlines
Wed, Jan 21 - Wed, Jan 28
Delta Logo
12:45 pm - 7:40 pm
CAE
-
EYW
6h 55m1 stop
Delta Logo
7:10 am - 11:58 am
EYW
-
CAE
4h 48m1 stop
$279Delta
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
1:51 pm - 6:06 pm
CAE
-
EYW
4h 15m1 stop
American Airlines Logo
1:33 pm - 10:59 pm
EYW
-
CAE
9h 26m2 stops
$284American Airlines
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
1:51 pm - 11:56 pm
CAE
-
EYW
10h 05m2 stops
American Airlines Logo
4:37 pm - 10:59 pm
EYW
-
CAE
6h 22m2 stops
$289American Airlines
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
11:59 am - 6:01 pm
CAE
-
EYW
6h 02m1 stop
American Airlines Logo
7:08 am - 1:22 pm
EYW
-
CAE
6h 14m1 stop
$294American Airlines
Fri, Jan 23 - Tue, Jan 27
American Airlines Logo
11:59 am - 6:01 pm
CAE
-
EYW
6h 02m1 stop
American Airlines Logo
6:06 am - 1:22 pm
EYW
-
CAE
7h 16m2 stops
$299American Airlines
Fri, Jan 23 - Tue, Jan 27
American Airlines Logo
6:18 pm - 10:43 pm
CAE
-
EYW
4h 25m1 stop
American Airlines Logo
6:20 pm - 10:58 pm
EYW
-
CAE
4h 38m1 stop
$329American Airlines
Sat, Feb 21 - Tue, Feb 24
American Airlines Logo
2:38 pm - 10:54 pm
CAE
-
EYW
8h 16m2 stops
American Airlines Logo
6:20 pm - 10:58 pm
EYW
-
CAE
4h 38m1 stop
$341American Airlines
Sat, Feb 21 - Tue, Feb 24
American Airlines Logo
6:18 pm - 10:43 pm
CAE
-
EYW
4h 25m1 stop
American Airlines Logo
8:14 am - 1:41 pm
EYW
-
CAE
5h 27m1 stop
$362American Airlines
Sat, Feb 21 - Tue, Feb 24

United Airlines flights from Columbia to Key West

Our best United Airlines deals on Columbia to Key West flight tickets
United Airlines
Jan 24
CAE7:30 pmColumbia Metropolitan
20h 52m
1 stop
EYW4:22 pmKey West
Jan 28
EYW6:05 pmKey West
5h 39m
1 stop
CAE11:44 pmColumbia Metropolitan
$443
Find similar
United Airlines
Jan 24
CAE2:49 pmColumbia Metropolitan
22h 14m
2 stops
EYW1:03 pmKey West
Jan 28
EYW6:05 pmKey West
5h 39m
1 stop
CAE11:44 pmColumbia Metropolitan
$448
Find similar
United Airlines
Jan 12
CAE8:00 amColumbia Metropolitan
7h 17m
1 stop
EYW3:17 pmKey West
Jan 16
EYW6:05 pmKey West
24h 50m
1 stop
CAE6:55 pmColumbia Metropolitan
$473
Find similar

American Airlines flights from Columbia to Key West

Our best American Airlines deals on Columbia to Key West flight tickets
American Airlines
Jan 21
CAE11:59 amColumbia Metropolitan
6h 02m
1 stop
EYW6:01 pmKey West
Jan 28
EYW4:37 pmKey West
6h 22m
2 stops
CAE10:59 pmColumbia Metropolitan
$274
Find similar
American Airlines
Jan 10
CAE1:51 pmColumbia Metropolitan
4h 15m
1 stop
EYW6:06 pmKey West
Jan 14
EYW1:33 pmKey West
9h 26m
2 stops
CAE10:59 pmColumbia Metropolitan
$284
Find similar
American Airlines
Jan 10
CAE1:51 pmColumbia Metropolitan
10h 05m
2 stops
EYW11:56 pmKey West
Jan 14
EYW4:37 pmKey West
6h 22m
2 stops
CAE10:59 pmColumbia Metropolitan
$289
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Columbia to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 1/21

12:45 pm-7:40 pm

1 stop6h 55m

Key West

Wed 1/28

7:10 am-11:58 am

1 stop4h 48m

$269

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 1/21

11:59 am-6:01 pm

1 stop6h 02m

Key West

Wed 1/28

4:37 pm-10:59 pm

2 stops6h 22m

$274

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 1/10

12:45 pm-7:40 pm

1 stop6h 55m

Key West

Wed 1/14

7:10 am-11:58 am

1 stop4h 48m

$279

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 1/10

1:51 pm-6:06 pm

1 stop4h 15m

Key West

Wed 1/14

1:33 pm-10:59 pm

2 stops9h 26m

$284

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 1/10

1:51 pm-11:56 pm

2 stops10h 05m

Key West

Wed 1/14

4:37 pm-10:59 pm

2 stops6h 22m

$289

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 1/23

11:59 am-6:01 pm

1 stop6h 02m

Key West

Tue 1/27

7:08 am-1:22 pm

1 stop6h 14m

$294

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 1/23

11:59 am-6:01 pm

1 stop6h 02m

Key West

Tue 1/27

6:06 am-1:22 pm

2 stops7h 16m

$299

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 2/21

6:18 pm-10:43 pm

1 stop4h 25m

Key West

Tue 2/24

6:20 pm-10:58 pm

1 stop4h 38m

$329

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 2/21

2:38 pm-10:54 pm

2 stops8h 16m

Key West

Tue 2/24

6:20 pm-10:58 pm

1 stop4h 38m

$341

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 2/21

6:18 pm-10:43 pm

1 stop4h 25m

Key West

Tue 2/24

8:14 am-1:41 pm

1 stop5h 27m

$362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbia to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, November is the cheapest month to fly from Columbia to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $331. If you are unable to visit Key West during the month of November, then departing from Columbia during the month January is also very affordable. Most momondo users find prices during this month for around $415.

When to book flights from Columbia to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia to Key West (CAE to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia to Key West

Fastest flight time

3h 58m

Direct flights

None
The fastest flight from Columbia to Key West takes 3h 58m
There are no direct flights from Columbia to Key West. There are no popular flight routes from Columbia to Key West.
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  • How far is Columbia Metropolitan to Key West by plane?

    There are 653.8 mi between Columbia Metropolitan and Key West. 3h 58m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Columbia Metropolitan Airport to Key West Airport?

    Prices for flights from Columbia Metropolitan Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Columbia Metropolitan Airport to Key West Airport?

  • How old do you have to be to fly from Columbia Metropolitan Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbia Metropolitan Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia to Key West?

Best airlines flying from Columbia to Key West

Compare and see reviews for airlines that fly from Columbia to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
8,019 reviews
Search Delta flights
American AirlinesPriceFrom $353Free CancellationRating
7.2
11,072 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Key West?

It is quick and easy to find Columbia to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbia to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Key West?

momondo provides multiple filters to help you find the best flight to Key West from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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