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Cheap flights from Columbia to Key West from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia to Key West departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:50 pm - 11:30 am
CAE
-
EYW
13h 40m
1 stop
Multiple Airlines Logo
2:35 pm - 9:02 pm
EYW
-
CAE
6h 27m
1 stop
$216Multiple Airlines
Mon, Mar 23 - Fri, Mar 27
Multiple Airlines Logo
9:50 pm - 12:21 pm
CAE
-
EYW
14h 31m
2 stops
Multiple Airlines Logo
2:35 pm - 9:02 pm
EYW
-
CAE
6h 27m
1 stop
$258Multiple Airlines
Mon, Mar 23 - Fri, Mar 27
Delta Logo
3:09 pm - 7:42 pm
CAE
-
EYW
4h 33m
1 stop
Delta Logo
7:10 am - 12:00 pm
EYW
-
CAE
4h 50m
1 stop
$339Delta
Wed, Feb 25 - Wed, Mar 4
Delta Logo
5:35 am - 10:59 am
CAE
-
EYW
5h 24m
1 stop
Delta Logo
7:10 am - 12:00 pm
EYW
-
CAE
4h 50m
1 stop
$364Delta
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
10:09 am - 7:15 pm
CAE
-
EYW
9h 06m
2 stops
American Airlines Logo
8:04 am - 1:42 pm
EYW
-
CAE
5h 38m
1 stop
$377American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
10:09 am - 7:15 pm
CAE
-
EYW
9h 06m
2 stops
American Airlines Logo
8:04 am - 1:42 pm
EYW
-
CAE
5h 38m
1 stop
$402American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
10:09 am - 7:15 pm
CAE
-
EYW
9h 06m
2 stops
American Airlines Logo
1:55 pm - 10:56 pm
EYW
-
CAE
9h 01m
2 stops
$414American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
12:09 pm - 7:15 pm
CAE
-
EYW
7h 06m
2 stops
American Airlines Logo
8:04 am - 1:42 pm
EYW
-
CAE
5h 38m
1 stop
$427American Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
10:09 am - 7:15 pm
CAE
-
EYW
9h 06m
2 stops
American Airlines Logo
1:55 pm - 10:56 pm
EYW
-
CAE
9h 01m
2 stops
$438American Airlines
Wed, Feb 25 - Wed, Mar 4
Delta Logo
1:30 pm - 7:42 pm
CAE
-
EYW
6h 12m
1 stop
Delta Logo
5:56 pm - 11:47 pm
EYW
-
CAE
5h 51m
1 stop
$449Delta
Sat, Feb 28 - Sat, Mar 7

Delta flights from Columbia to Key West

Our best Delta deals on Columbia to Key West flight tickets
Delta
Feb 25
CAE3:09 pmColumbia Metropolitan
4h 33m
1 stop
EYW7:42 pmKey West
Mar 4
EYW7:10 amKey West
4h 50m
1 stop
CAE12:00 pmColumbia Metropolitan
$339
Delta
Feb 21
CAE5:35 amColumbia Metropolitan
5h 24m
1 stop
EYW10:59 amKey West
Feb 25
EYW7:10 amKey West
4h 50m
1 stop
CAE12:00 pmColumbia Metropolitan
$364
Delta
Feb 28
CAE1:30 pmColumbia Metropolitan
6h 12m
1 stop
EYW7:42 pmKey West
Mar 7
EYW5:56 pmKey West
5h 51m
1 stop
CAE11:47 pmColumbia Metropolitan
$449

United Airlines flights from Columbia to Key West

Our best United Airlines deals on Columbia to Key West flight tickets
United Airlines
Feb 21
CAE9:00 amColumbia Metropolitan
8h 54m
1 stop
EYW5:54 pmKey West
Feb 24
EYW6:35 pmKey West
5h 09m
1 stop
CAE11:44 pmColumbia Metropolitan
$459
United Airlines
Feb 21
CAE9:00 amColumbia Metropolitan
8h 54m
1 stop
EYW5:54 pmKey West
Feb 24
EYW3:56 pmKey West
31h 48m
2 stops
CAE11:44 pmColumbia Metropolitan
$558
United Airlines
Feb 21
CAE9:00 amColumbia Metropolitan
8h 54m
1 stop
EYW5:54 pmKey West
Feb 24
EYW4:52 pmKey West
30h 52m
2 stops
CAE11:44 pmColumbia Metropolitan
$619

momondo Fare Finder

 
Customize your flight search to find flights from Columbia to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Columbia to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Mon 3/23

9:50 pm-11:30 am

1 stop13h 40m

Key West

Fri 3/27

2:35 pm-9:02 pm

1 stop6h 27m

$216

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Mon 3/23

9:50 pm-12:21 pm

2 stops14h 31m

Key West

Fri 3/27

2:35 pm-9:02 pm

1 stop6h 27m

$258

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 2/25

3:09 pm-7:42 pm

1 stop4h 33m

Key West

Wed 3/4

7:10 am-12:00 pm

1 stop4h 50m

$339

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 2/21

5:35 am-10:59 am

1 stop5h 24m

Key West

Wed 2/25

7:10 am-12:00 pm

1 stop4h 50m

$364

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 2/25

10:09 am-7:15 pm

2 stops9h 06m

Key West

Wed 3/4

8:04 am-1:42 pm

1 stop5h 38m

$377

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 2/25

10:09 am-7:15 pm

2 stops9h 06m

Key West

Wed 3/4

8:04 am-1:42 pm

1 stop5h 38m

$402

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 2/25

10:09 am-7:15 pm

2 stops9h 06m

Key West

Wed 3/4

1:55 pm-10:56 pm

2 stops9h 01m

$414

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 2/25

12:09 pm-7:15 pm

2 stops7h 06m

Key West

Wed 3/4

8:04 am-1:42 pm

1 stop5h 38m

$427

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Wed 2/25

10:09 am-7:15 pm

2 stops9h 06m

Key West

Wed 3/4

1:55 pm-10:56 pm

2 stops9h 01m

$438

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 2/28

1:30 pm-7:42 pm

1 stop6h 12m

Key West

Sat 3/7

5:56 pm-11:47 pm

1 stop5h 51m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbia to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbia and Key West?

What is the cheapest month to fly to Key West?

In general, November is the cheapest month to fly from Columbia to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $331. If you are unable to visit Key West during the month of November, then departing from Columbia during the month September is also very affordable. Most momondo users find prices during this month for around $449.

When to book flights from Columbia to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia to Key West (CAE to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia to Key West

Fastest flight time

3h 39m

Direct flights

None
The fastest flight from Columbia to Key West takes 3h 39m
There are no direct flights from Columbia to Key West. There are no popular flight routes from Columbia to Key West.
Search flight deals

  • How far is Columbia Metropolitan to Key West by plane?

    There are 653.8 mi between Columbia Metropolitan and Key West. 3h 39m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Columbia Metropolitan Airport to Key West Airport?

    Prices for flights from Columbia Metropolitan Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Columbia Metropolitan Airport to Key West Airport?

  • How old do you have to be to fly from Columbia Metropolitan Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbia Metropolitan Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia to Key West?

Best airlines flying from Columbia to Key West

Compare and see reviews for airlines that fly from Columbia to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
8,180 reviews
Search Delta flights
American AirlinesPriceFrom $353Free CancellationRating
7.2
11,265 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Key West?

It is quick and easy to find Columbia to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbia to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Key West?

momondo provides multiple filters to help you find the best flight to Key West from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Key West trip

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