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Cheap flights from Columbia to Key West from $374

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia to Key West departing on 7/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 10:58 am
CAE
-
EYW
4h 58m
1 stop
American Airlines Logo
7:55 pm - 11:55 pm
EYW
-
CAE
4h 00m
1 stop
$374American Airlines
Sat, Jul 25 - Sat, Aug 1
American Airlines Logo
12:31 pm - 6:49 pm
CAE
-
EYW
6h 18m
1 stop
American Airlines Logo
7:49 pm - 11:59 pm
EYW
-
CAE
4h 10m
1 stop
$384American Airlines
Tue, May 26 - Sat, May 30
Delta Logo
11:55 am - 5:14 pm
CAE
-
EYW
5h 19m
1 stop
Delta Logo
7:00 am - 12:28 pm
EYW
-
CAE
5h 28m
1 stop
$443Delta
Sat, Sep 26 - Sat, Oct 3
Delta Logo
5:40 am - 10:53 am
CAE
-
EYW
5h 13m
1 stop
Delta Logo
6:19 pm - 11:47 pm
EYW
-
CAE
5h 28m
1 stop
$451Delta
Sat, May 30 - Sat, Jun 6
American Airlines Logo
6:00 am - 1:09 pm
CAE
-
EYW
7h 09m
1 stop
American Airlines Logo
7:29 pm - 11:56 pm
EYW
-
CAE
4h 27m
1 stop
$488American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
8:49 am - 7:23 pm
CAE
-
EYW
10h 34m
2 stops
American Airlines Logo
7:55 pm - 11:55 pm
EYW
-
CAE
4h 00m
1 stop
$505American Airlines
Sat, Jul 25 - Sat, Aug 1
American Airlines Logo
8:49 am - 7:19 pm
CAE
-
EYW
10h 30m
2 stops
American Airlines Logo
7:29 pm - 11:56 pm
EYW
-
CAE
4h 27m
1 stop
$515American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
2:30 pm - 6:49 pm
CAE
-
EYW
4h 19m
1 stop
American Airlines Logo
7:29 pm - 11:59 pm
EYW
-
CAE
4h 30m
1 stop
$537American Airlines
Mon, Jun 1 - Thu, Jun 4
American Airlines Logo
6:00 am - 10:58 am
CAE
-
EYW
4h 58m
1 stop
American Airlines Logo
7:33 pm - 11:58 pm
EYW
-
CAE
4h 25m
1 stop
$557American Airlines
Sat, Jul 11 - Wed, Jul 15
American Airlines Logo
5:00 am - 1:07 pm
CAE
-
EYW
8h 07m
2 stops
American Airlines Logo
7:49 pm - 11:59 pm
EYW
-
CAE
4h 10m
1 stop
$560American Airlines
Tue, May 26 - Sat, May 30

United Airlines flights from Columbia to Key West

Our best United Airlines deals on Columbia to Key West flight tickets
United Airlines
Jul 11
CAE10:31 amColumbia Metropolitan
28h 48m
2 stops
EYW3:19 pmKey West
Jul 15
EYW2:26 pmKey West
23h 50m
2 stops
CAE2:16 pmColumbia Metropolitan
$789
United Airlines
May 30
CAE10:31 amColumbia Metropolitan
26h 59m
2 stops
EYW1:30 pmKey West
Jun 6
EYW2:26 pmKey West
20h 13m
1 stop
CAE10:39 amColumbia Metropolitan
$1,069
United Airlines
Jun 19
CAE7:45 pmColumbia Metropolitan
17h 45m
2 stops
EYW1:30 pmKey West
Jun 22
EYW2:26 pmKey West
43h 30m
2 stops
CAE9:56 amColumbia Metropolitan
$1,075

Delta flights from Columbia to Key West

Our best Delta deals on Columbia to Key West flight tickets
Delta
Sep 26
CAE11:55 amColumbia Metropolitan
5h 19m
1 stop
EYW5:14 pmKey West
Oct 3
EYW7:00 amKey West
5h 28m
1 stop
CAE12:28 pmColumbia Metropolitan
$443
Delta
May 30
CAE5:40 amColumbia Metropolitan
5h 13m
1 stop
EYW10:53 amKey West
Jun 6
EYW6:19 pmKey West
5h 28m
1 stop
CAE11:47 pmColumbia Metropolitan
$451
Delta
Jun 9
CAE1:47 pmColumbia Metropolitan
6h 06m
1 stop
EYW7:53 pmKey West
Jun 15
EYW7:50 amKey West
5h 12m
1 stop
CAE1:02 pmColumbia Metropolitan
$669

momondo Fare Finder

 
Customize your flight search to find flights from Columbia to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Columbia to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 7/25

6:00 am-10:58 am

1 stop4h 58m

Key West

Sat 8/1

7:55 pm-11:55 pm

1 stop4h 00m

$374

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 5/26

12:31 pm-6:49 pm

1 stop6h 18m

Key West

Sat 5/30

7:49 pm-11:59 pm

1 stop4h 10m

$384

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 9/26

11:55 am-5:14 pm

1 stop5h 19m

Key West

Sat 10/3

7:00 am-12:28 pm

1 stop5h 28m

$443

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 5/30

5:40 am-10:53 am

1 stop5h 13m

Key West

Sat 6/6

6:19 pm-11:47 pm

1 stop5h 28m

$451

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 5/23

6:00 am-1:09 pm

1 stop7h 09m

Key West

Wed 5/27

7:29 pm-11:56 pm

1 stop4h 27m

$488

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 7/25

8:49 am-7:23 pm

2 stops10h 34m

Key West

Sat 8/1

7:55 pm-11:55 pm

1 stop4h 00m

$505

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 5/23

8:49 am-7:19 pm

2 stops10h 30m

Key West

Wed 5/27

7:29 pm-11:56 pm

1 stop4h 27m

$515
Quickest round-trip

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Mon 6/1

2:30 pm-6:49 pm

1 stop4h 19m

Key West

Thu 6/4

7:29 pm-11:59 pm

1 stop4h 30m

$537

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sat 7/11

6:00 am-10:58 am

1 stop4h 58m

Key West

Wed 7/15

7:33 pm-11:58 pm

1 stop4h 25m

$557

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 5/26

5:00 am-1:07 pm

2 stops8h 07m

Key West

Sat 5/30

7:49 pm-11:59 pm

1 stop4h 10m

$560

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Columbia to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Key West?

In general, November is the cheapest month to fly from Columbia to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $331. If you are unable to visit Key West during the month of November, then departing from Columbia during the month January is also very affordable. Most momondo users find prices during this month for around $476.

When to book flights from Columbia to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia to Key West (CAE to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia to Key West

Fastest flight time

3h 55m

Direct flights

None
The fastest flight from Columbia to Key West takes 3h 55m
There are no direct flights from Columbia to Key West. There are no popular flight routes from Columbia to Key West.
Search flight deals

Frequently asked questions about flying from Columbia to Key West

  • How far is Columbia Metropolitan to Key West by plane?

    There are 653.8 mi between Columbia Metropolitan and Key West. 3h 55m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Columbia Metropolitan Airport to Key West Airport?

    Prices for flights from Columbia Metropolitan Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Columbia Metropolitan Airport to Key West Airport?

  • How old do you have to be to fly from Columbia Metropolitan Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbia Metropolitan Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia to Key West?

Best airlines flying from Columbia to Key West

Compare and see reviews for airlines that fly from Columbia to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $258Free CancellationRating
7.9
8,448 reviews
Search Delta flights
American AirlinesPriceFrom $353Free CancellationRating
7.1
11,665 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Key West?

It is quick and easy to find Columbia to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbia to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Key West?

momondo provides multiple filters to help you find the best flight to Key West from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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