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Cheap flights from Columbia to Key West from $419

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia to Key West departing on 4/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:59 pm - 7:49 pm
CAE
-
EYW
5h 50m
1 stop
Delta Logo
7:30 am - 1:14 pm
EYW
-
CAE
5h 44m
1 stop
$427Delta
Fri, May 8 - Fri, May 15
Delta Logo
1:59 pm - 7:40 pm
CAE
-
EYW
5h 41m
1 stop
Delta Logo
7:33 am - 11:29 am
EYW
-
CAE
3h 56m
1 stop
$499Delta
Tue, Apr 21 - Tue, Apr 28
Delta Logo
1:47 pm - 7:53 pm
CAE
-
EYW
6h 06m
1 stop
Delta Logo
1:18 pm - 5:12 pm
EYW
-
CAE
3h 54m
1 stop
$539Delta
Fri, Jun 26 - Tue, Jun 30
Delta Logo
1:47 pm - 7:53 pm
CAE
-
EYW
6h 06m
1 stop
Delta Logo
6:24 pm - 11:45 pm
EYW
-
CAE
5h 21m
1 stop
$549Delta
Fri, Jun 12 - Mon, Jun 15
Delta Logo
6:45 am - 10:46 am
CAE
-
EYW
4h 01m
1 stop
Delta Logo
7:33 am - 1:14 pm
EYW
-
CAE
5h 41m
1 stop
$557Delta
Sun, Apr 19 - Wed, Apr 22
American Airlines Logo
2:43 pm - 10:58 pm
CAE
-
EYW
8h 15m
2 stops
American Airlines Logo
8:05 am - 12:20 pm
EYW
-
CAE
4h 15m
1 stop
$562American Airlines
Sun, Apr 19 - Wed, Apr 22
United Airlines Logo
10:50 am - 4:42 pm
CAE
-
EYW
5h 52m
1 stop
United Airlines Logo
6:22 pm - 2:49 pm
EYW
-
CAE
20h 27m
2 stops
$575United Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
6:00 am - 3:24 pm
CAE
-
EYW
9h 24m
1 stop
American Airlines Logo
12:04 pm - 9:45 pm
EYW
-
CAE
9h 41m
1 stop
$638American Airlines
Fri, May 15 - Mon, May 18
American Airlines Logo
12:48 pm - 10:58 pm
CAE
-
EYW
10h 10m
2 stops
American Airlines Logo
8:05 am - 2:16 pm
EYW
-
CAE
6h 11m
1 stop
$645American Airlines
Fri, May 15 - Mon, May 18
American Airlines Logo
2:43 pm - 10:58 pm
CAE
-
EYW
8h 15m
2 stops
American Airlines Logo
6:45 am - 3:46 pm
EYW
-
CAE
9h 01m
2 stops
$650American Airlines
Sun, Apr 19 - Wed, Apr 22

Delta flights from Columbia to Key West

Our best Delta deals on Columbia to Key West flight tickets
Delta
May 8
CAE1:59 pmColumbia Metropolitan
5h 50m
1 stop
EYW7:49 pmKey West
May 15
EYW7:30 amKey West
5h 44m
1 stop
CAE1:14 pmColumbia Metropolitan
$427
Delta
Apr 21
CAE1:59 pmColumbia Metropolitan
5h 41m
1 stop
EYW7:40 pmKey West
Apr 28
EYW7:33 amKey West
3h 56m
1 stop
CAE11:29 amColumbia Metropolitan
$499
Delta
Jun 26
CAE1:47 pmColumbia Metropolitan
6h 06m
1 stop
EYW7:53 pmKey West
Jun 30
EYW1:18 pmKey West
3h 54m
1 stop
CAE5:12 pmColumbia Metropolitan
$539

American Airlines flights from Columbia to Key West

Our best American Airlines deals on Columbia to Key West flight tickets
American Airlines
Apr 19
CAE2:43 pmColumbia Metropolitan
8h 15m
2 stops
EYW10:58 pmKey West
Apr 22
EYW8:05 amKey West
4h 15m
1 stop
CAE12:20 pmColumbia Metropolitan
$562
American Airlines
Apr 2
CAE9:04 amColumbia Metropolitan
6h 53m
1 stop
EYW3:57 pmKey West
Apr 5
EYW4:40 pmKey West
5h 15m
1 stop
CAE9:55 pmColumbia Metropolitan
$627
American Airlines
May 15
CAE6:00 amColumbia Metropolitan
9h 24m
1 stop
EYW3:24 pmKey West
May 18
EYW12:04 pmKey West
9h 41m
1 stop
CAE9:45 pmColumbia Metropolitan
$638

momondo Fare Finder

 
Customize your flight search to find flights from Columbia to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Columbia to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 5/8

1:59 pm-7:49 pm

1 stop5h 50m

Key West

Fri 5/15

7:30 am-1:14 pm

1 stop5h 44m

$427
Quickest round-trip

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 4/21

1:59 pm-7:40 pm

1 stop5h 41m

Key West

Tue 4/28

7:33 am-11:29 am

1 stop3h 56m

$499

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 6/26

1:47 pm-7:53 pm

1 stop6h 06m

Key West

Tue 6/30

1:18 pm-5:12 pm

1 stop3h 54m

$539

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 6/12

1:47 pm-7:53 pm

1 stop6h 06m

Key West

Mon 6/15

6:24 pm-11:45 pm

1 stop5h 21m

$549

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sun 4/19

6:45 am-10:46 am

1 stop4h 01m

Key West

Wed 4/22

7:33 am-1:14 pm

1 stop5h 41m

$557

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sun 4/19

2:43 pm-10:58 pm

2 stops8h 15m

Key West

Wed 4/22

8:05 am-12:20 pm

1 stop4h 15m

$562

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 4/21

10:50 am-4:42 pm

1 stop5h 52m

Key West

Tue 4/28

6:22 pm-2:49 pm

2 stops20h 27m

$575

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 5/15

6:00 am-3:24 pm

1 stop9h 24m

Key West

Mon 5/18

12:04 pm-9:45 pm

1 stop9h 41m

$638

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Fri 5/15

12:48 pm-10:58 pm

2 stops10h 10m

Key West

Mon 5/18

8:05 am-2:16 pm

1 stop6h 11m

$645

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Sun 4/19

2:43 pm-10:58 pm

2 stops8h 15m

Key West

Wed 4/22

6:45 am-3:46 pm

2 stops9h 01m

$650

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Columbia to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbia and Key West?

What is the cheapest month to fly to Key West?

In general, November is the cheapest month to fly from Columbia to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $331. If you are unable to visit Key West during the month of November, then departing from Columbia during the month September is also very affordable. Most momondo users find prices during this month for around $449.

When to book flights from Columbia to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia to Key West (CAE to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia to Key West

Fastest flight time

5h 14m

Direct flights

None
The fastest flight from Columbia to Key West takes 5h 14m
There are no direct flights from Columbia to Key West. There are no popular flight routes from Columbia to Key West.
Search flight deals

  • How far is Columbia Metropolitan to Key West by plane?

    There are 653.8 mi between Columbia Metropolitan and Key West. 5h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Columbia Metropolitan Airport to Key West Airport?

    Prices for flights from Columbia Metropolitan Airport to Key West Airport were last updated today.

  • How many operators does momondo search for flights from Columbia Metropolitan Airport to Key West Airport?

  • How old do you have to be to fly from Columbia Metropolitan Airport to Key West Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Columbia Metropolitan Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia to Key West?

Best airlines flying from Columbia to Key West

Compare and see reviews for airlines that fly from Columbia to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $248Free CancellationRating
7.9
8,331 reviews
Search Delta flights
American AirlinesPriceFrom $331Free CancellationRating
7.1
11,495 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Key West?

It is quick and easy to find Columbia to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Columbia to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to Key West?

momondo provides multiple filters to help you find the best flight to Key West from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to Key West right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Key West from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Key West trip

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