What is the cheapest airline that flies from Columbia Regional to North Carolina?

Allegiant Air, American Airlines, and United Airlines are the most popular carriers operating from Columbia Regional to North Carolina

How many flights depart from Columbia, Missouri to North Carolina on average per week?

As of September 2026, there are 6 flights per week flying from Columbia, Missouri to North Carolina. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.

When did momondo last update prices for flights from Columbia Regional Airport to North Carolina?

Prices for flights from Columbia Regional Airport to North Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Columbia Regional Airport to North Carolina?

The number of operators available for flights from Columbia Regional Airport to North Carolina is 2 as of September 2026.

How old do you have to be to fly from Columbia Regional Airport to North Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to North Carolina.

What documentation or ID do you need to fly to North Carolina?

The required travel and health documents for your North Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at North Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$114 Cheap Flights from Columbia, Missouri to North Carolina in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Columbia, Missouri to North Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:49 pm - 10:20 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

6h 31m1 stop Valparaiso Destin-Ft Walton Beach

9:26 am - 7:43 pmTYS Knoxville McGhee Tyson-COU Columbia Regional

11h 17m1 stop Valparaiso Destin-Ft Walton Beach

$251Allegiant Air

Mon, Oct 5 - Fri, Oct 9

12:29 pm - 9:39 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

8h 10m1 stop Orlando Sanford Intl

2:01 pm - 2:16 pmTYS Knoxville McGhee Tyson-COU Columbia Regional

25h 15m1 stop Valparaiso Destin-Ft Walton Beach

$281Allegiant Air

Mon, Oct 19 - Thu, Oct 29

12:59 pm - 9:41 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

7h 42m1 stop Orlando Sanford Intl

2:01 pm - 2:16 pmTYS Knoxville McGhee Tyson-COU Columbia Regional

25h 15m1 stop Valparaiso Destin-Ft Walton Beach

$284Allegiant Air

Fri, Oct 23 - Thu, Oct 29

6:24 pm - 11:59 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

4h 35m1 stop Chicago O'Hare Intl

4:38 pm - 8:55 pmTYS Knoxville McGhee Tyson-COU Columbia Regional

5h 17m1 stop Chicago O'Hare Intl

$288American Airlines

Wed, Oct 7 - Tue, Oct 13

6:15 am - 2:42 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

7h 27m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:00 am - 10:39 amTYS Knoxville McGhee Tyson-COU Columbia Regional

5h 39m1 stop Chicago O'Hare Intl

$294United Airlines

Wed, Oct 7 - Tue, Oct 13

11:33 am - 8:37 amCOU Columbia Regional-CLT Charlotte Douglas

20h 04m1 stop Orlando Sanford Intl

9:32 am - 10:43 amCLT Charlotte Douglas-COU Columbia Regional

26h 11m1 stop Orlando

$298Multiple Airlines

Mon, Nov 9 - Sun, Nov 15

6:28 pm - 11:47 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

4h 19m1 stop Chicago O'Hare Intl

11:34 am - 2:57 pmTYS Knoxville McGhee Tyson-COU Columbia Regional

4h 23m1 stop Chicago O'Hare Intl

$303American Airlines

Mon, Nov 23 - Thu, Nov 26

8:16 am - 4:31 pmCOU Columbia Regional-ORF Norfolk

7h 15m1 stop Charlotte Douglas

6:17 pm - 10:39 pmORF Norfolk-COU Columbia Regional

5h 22m1 stop Charlotte Douglas

$308American Airlines

Thu, Oct 1 - Mon, Oct 5

3:19 pm - 11:59 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

7h 40m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:00 am - 10:39 amTYS Knoxville McGhee Tyson-COU Columbia Regional

5h 39m1 stop Chicago O'Hare Intl

$324United Airlines

Sat, Sep 26 - Wed, Sep 30

6:15 am - 12:15 pmCOU Columbia Regional-ORF Norfolk

5h 00m1 stop Chicago O'Hare Intl

6:00 am - 3:08 pmORF Norfolk-COU Columbia Regional

10h 08m2 stops Newark Chicago O'Hare Intl

$349United Airlines

Wed, Sep 30 - Tue, Oct 6

Cheap last minute flights

Enter your travel dates to find the best prices.

5:28 pm - 7:53 pmCOU Columbia Regional-TYS Knoxville McGhee Tyson

25h 25m1 stop Orlando Sanford Intl

9:00 am - 5:32 pmTYS Knoxville McGhee Tyson-COU Columbia Regional

9h 32m1 stop Orlando Sanford Intl

$338Allegiant Air

Fri, Sep 18 - Mon, Sep 21

5:28 pm - 11:56 amCOU Columbia Regional-AVL Asheville Regional

17h 28m1 stop Orlando Sanford Intl

6:48 pm - 4:41 pmAVL Asheville Regional-COU Columbia Regional

22h 53m1 stop Orlando Sanford Intl

$343Allegiant Air

Fri, Sep 18 - Thu, Sep 24

5:28 pm - 11:56 amCOU Columbia Regional-AVL Asheville Regional

17h 28m1 stop Orlando Sanford Intl

6:30 am - 4:41 pmAVL Asheville Regional-COU Columbia Regional

11h 11m1 stop Orlando Sanford Intl

$356Allegiant Air

Fri, Sep 18 - Fri, Sep 25

4:51 pm - 11:07 pmCOU Columbia Regional-AVL Asheville Regional

5h 16m1 stop Dallas/Fort Worth

6:55 pm - 10:08 pmAVL Asheville Regional-COU Columbia Regional

4h 13m1 stop Charlotte Douglas

$383American Airlines

Wed, Sep 16 - Wed, Sep 30

5:28 pm - 11:56 amCOU Columbia Regional-AVL Asheville Regional

17h 28m1 stop Orlando Sanford Intl

1:42 pm - 12:14 pmAVL Asheville Regional-COU Columbia Regional

23h 32m1 stop Orlando Sanford Intl

$410Allegiant Air

Fri, Sep 18 - Thu, Oct 1

10:38 am - 7:15 pmCOU Columbia Regional-AVL Asheville Regional

7h 37m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

11:27 am - 6:02 pmAVL Asheville Regional-COU Columbia Regional

7h 35m1 stop Chicago O'Hare Intl

$430American Airlines

Wed, Sep 16 - Wed, Sep 30

11:17 am - 4:59 pmCOU Columbia Regional-AVL Asheville Regional

4h 42m1 stop Chicago O'Hare Intl

5:40 pm - 10:55 pmAVL Asheville Regional-COU Columbia Regional

6h 15m1 stop Chicago O'Hare Intl

$433United Airlines

Sat, Sep 19 - Sat, Oct 3

5:44 am - 10:57 amCOU Columbia Regional-AVL Asheville Regional

4h 13m1 stop Chicago O'Hare Intl

6:55 pm - 10:08 pmAVL Asheville Regional-COU Columbia Regional

4h 13m1 stop Charlotte Douglas

$433American Airlines

Sat, Sep 19 - Fri, Oct 2

11:17 am - 4:59 pmCOU Columbia Regional-AVL Asheville Regional

4h 42m1 stop Chicago O'Hare Intl

10:50 am - 8:33 pmAVL Asheville Regional-COU Columbia Regional

10h 43m2 stops Chicago O'Hare Intl Denver Intl

$439United Airlines

Sat, Sep 19 - Sat, Oct 3

11:17 am - 4:59 pmCOU Columbia Regional-AVL Asheville Regional

4h 42m1 stop Chicago O'Hare Intl

6:40 am - 10:39 amAVL Asheville Regional-COU Columbia Regional

4h 59m1 stop Chicago O'Hare Intl

$448United Airlines

Sat, Sep 19 - Thu, Sep 24

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American Airlines flights from Columbia, Missouri to North Carolina

Our best American Airlines deals on Columbia, Missouri to North Carolina flight tickets

American Airlines

Oct 7

COU6:24 pmColumbia Regional

4h 35m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

Oct 13

TYS4:38 pmKnoxville McGhee Tyson

5h 17m

1 stop

COU8:55 pmColumbia Regional

$288

American Airlines

Nov 23

COU6:28 pmColumbia Regional

4h 19m

1 stop

TYS11:47 pmKnoxville McGhee Tyson

Nov 26

TYS11:34 amKnoxville McGhee Tyson

4h 23m

1 stop

COU2:57 pmColumbia Regional

$303

American Airlines

Oct 1

COU8:16 amColumbia Regional

7h 15m

1 stop

ORF4:31 pmNorfolk

Oct 5

ORF6:17 pmNorfolk

5h 22m

1 stop

COU10:39 pmColumbia Regional

$308

United Airlines flights from Columbia, Missouri to North Carolina

Our best United Airlines deals on Columbia, Missouri to North Carolina flight tickets

United Airlines

Oct 7

COU6:15 amColumbia Regional

7h 27m

2 stops

TYS2:42 pmKnoxville McGhee Tyson

Oct 13

TYS6:00 amKnoxville McGhee Tyson

5h 39m

1 stop

COU10:39 amColumbia Regional

$294

United Airlines

Sep 26

COU3:19 pmColumbia Regional

7h 40m

2 stops

TYS11:59 pmKnoxville McGhee Tyson

Sep 30

TYS6:00 amKnoxville McGhee Tyson

5h 39m

1 stop

COU10:39 amColumbia Regional

$324

United Airlines

Sep 30

COU6:15 amColumbia Regional

5h 00m

1 stop

ORF12:15 pmNorfolk

Oct 6

ORF6:00 amNorfolk

10h 08m

2 stops

COU3:08 pmColumbia Regional

$349

momondo Fare Finder

Use the filters below to find and compare flights from Columbia, Missouri to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/5

2:49 pm-10:20 pm

1 stop6h 31m

Knoxville McGhee Tyson

Fri 10/9

9:26 am-7:43 pm

1 stop11h 17m

$251

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 10/19

12:29 pm-9:39 pm

1 stop8h 10m

Knoxville McGhee Tyson

Thu 10/29

2:01 pm-2:16 pm

1 stop25h 15m

$281

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Fri 10/23

12:59 pm-9:41 pm

1 stop7h 42m

Knoxville McGhee Tyson

Thu 10/29

2:01 pm-2:16 pm

1 stop25h 15m

$284

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Wed 10/7

6:24 pm-11:59 pm

1 stop4h 35m

Knoxville McGhee Tyson

Tue 10/13

4:38 pm-8:55 pm

1 stop5h 17m

$288

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Wed 10/7

6:15 am-2:42 pm

2 stops7h 27m

Knoxville McGhee Tyson

Tue 10/13

6:00 am-10:39 am

1 stop5h 39m

$294

ColumbiaCharlotte

COU Columbia Regional - CLT Charlotte Douglas

COUCLT

Columbia Regional

Mon 11/9

11:33 am-8:37 am

1 stop20h 04m

Charlotte Douglas

Sun 11/15

9:32 am-10:43 am

1 stop26h 11m

$298

Quickest round-trip

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Mon 11/23

6:28 pm-11:47 pm

1 stop4h 19m

Knoxville McGhee Tyson

Thu 11/26

11:34 am-2:57 pm

1 stop4h 23m

$303

ColumbiaNorfolk

COU Columbia Regional - ORF Norfolk

COUORF

Columbia Regional

Thu 10/1

8:16 am-4:31 pm

1 stop7h 15m

Norfolk

Mon 10/5

6:17 pm-10:39 pm

1 stop5h 22m

$308

ColumbiaKnoxville

COU Columbia Regional - TYS Knoxville McGhee Tyson

COUTYS

Columbia Regional

Sat 9/26

3:19 pm-11:59 pm

2 stops7h 40m

Knoxville McGhee Tyson

Wed 9/30

6:00 am-10:39 am

1 stop5h 39m

$324

ColumbiaNorfolk

COU Columbia Regional - ORF Norfolk

COUORF

Columbia Regional

Wed 9/30

6:15 am-12:15 pm

1 stop5h 00m

Norfolk

Tue 10/6

6:00 am-3:08 pm

2 stops10h 08m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Columbia, Missouri to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to North Carolina?

If you don’t want to visit North Carolina in February, then you should wait until April to fly from Columbia, Missouri, when ticket prices are also cheap, with an average price of $388.

What is the cheapest Columbia Regional to North Carolina flight route?

Fly from Columbia Regional to Charlotte Douglas for the best Columbia Regional - North Carolina flight prices

What cabin class options are available on Columbia, Missouri to North Carolina flights?

There are 3 cabin classes available to choose from on Columbia, Missouri to North Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Columbia, Missouri to North Carolina flights?

You could potentially save up to 41% on your flight if you consider stops on a Columbia, Missouri to North Carolina flight.

Cheap Columbia, Missouri to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to North Carolina

Best Price Found	$114
Fastest flight time	2h 12m
Direct flights	Every day
Airports in North Carolina	110 airports

The best one-way flight to North Carolina from Columbia, Missouri in the past 72 hours is $114. The best round-trip flight deal from Columbia, Missouri to North Carolina found on momondo in the last 72 hours is $251.

The fastest flight from Columbia, Missouri to North Carolina takes 2h 12m

Direct flights go from Columbia, Missouri to North Carolina every day.

There are 110 airports in North Carolina. From Columbia, Missouri there are direct flights to Charlotte Douglas (CLT).

Search flight deals

Frequently asked questions about flying from Columbia, Missouri to North Carolina

When did momondo last update prices for flights from Columbia Regional Airport to North Carolina?
Prices for flights from Columbia Regional Airport to North Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Columbia Regional Airport to North Carolina?
The number of operators available for flights from Columbia Regional Airport to North Carolina is 2 as of September 2026.
How old do you have to be to fly from Columbia Regional Airport to North Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to North Carolina.
What documentation or ID do you need to fly to North Carolina?
The required travel and health documents for your North Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at North Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Columbia, Missouri to North Carolina?
momondo data reveals that the most frequently booked plane model on the route from Columbia, Missouri to North Carolina is Embraer 175, representing 72.22% of all bookings. The subsequent popular models are Boeing 737 MAX 8 at 9.72%, Canadair (Bombardier) Regional Jet 900 at 8.33%, and Airbus A320-100/200 at 4.17%.

Best airlines flying from Columbia, Missouri to North Carolina

Compare and see reviews for airlines that fly from Columbia, Missouri to North Carolina with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $271	Free Cancellation	Rating 7.4 10,214 reviews		Search United Airlines flights
American Airlines	PriceFrom $298	Free Cancellation	Rating 7.1 12,049 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to North Carolina?

It is quick and easy to find Columbia to North Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to North Carolina that suits you.

Can I find flights from Columbia to North Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Columbia to North Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Columbia to North Carolina?

Once all potential Columbia to North Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Columbia to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.