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Cheap flights from Columbia, Missouri to North Carolina from $378

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to North Carolina departing on 9/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Columbia, Missouri to North Carolina

Cheap round-trip flights

American Airlines Logo
12:17 pm - 8:25 pmCOU-CLT
7h 08m1 stop
American Airlines Logo
1:36 pm - 6:44 pmCLT-COU
6h 08m1 stop
$378American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
12:17 pm - 6:22 pmCOU-CLT
5h 05m1 stop
American Airlines Logo
8:00 am - 1:09 pmCLT-COU
6h 09m2 stops
$384American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
12:28 pm - 8:37 pmCOU-CLT
7h 09m1 stop
American Airlines Logo
7:21 am - 12:00 pmCLT-COU
5h 39m1 stop
$400American Airlines
Find Deal
Wed, Sep 17 - Sun, Sep 21
American Airlines Logo
6:24 am - 3:31 pmCOU-MYR
8h 07m2 stops
American Airlines Logo
5:52 pm - 10:45 pmMYR-COU
5h 53m1 stop
$416American Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
4:23 pm - 10:51 pmCOU-MYR
5h 28m1 stop
American Airlines Logo
5:52 pm - 10:45 pmMYR-COU
5h 53m1 stop
$420American Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
6:24 am - 3:31 pmCOU-MYR
8h 07m2 stops
American Airlines Logo
8:06 am - 4:44 pmMYR-COU
9h 38m2 stops
$421American Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
American Airlines Logo
6:15 am - 12:26 pmCOU-TYS
5h 11m1 stop
American Airlines Logo
4:37 pm - 10:45 pmTYS-COU
7h 08m1 stop
$430American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
6:15 am - 5:47 pmCOU-TYS
10h 32m2 stops
American Airlines Logo
7:29 am - 11:58 amTYS-COU
5h 29m1 stop
$436American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
6:15 am - 5:47 pmCOU-TYS
10h 32m2 stops
American Airlines Logo
6:25 am - 1:09 pmTYS-COU
7h 44m2 stops
$441American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
4:23 pm - 10:51 pmCOU-MYR
5h 28m1 stop
American Airlines Logo
7:00 am - 12:00 pmMYR-COU
6h 00m1 stop
$469American Airlines
Find Deal
Wed, Sep 3 - Sun, Sep 7

American Airlines flights from Columbia, Missouri to North Carolina

Our best American Airlines deals on Columbia, Missouri to North Carolina flight tickets
American Airlines
Sep 2
COU12:17 pmColumbia Regional
7h 08m
1 stop
CLT8:25 pmCharlotte Douglas
Sep 6
CLT1:36 pmCharlotte Douglas
6h 08m
1 stop
COU6:44 pmColumbia Regional
$378
Find similar
American Airlines
Sep 2
COU12:17 pmColumbia Regional
5h 05m
1 stop
CLT6:22 pmCharlotte Douglas
Sep 6
CLT8:00 amCharlotte Douglas
6h 09m
2 stops
COU1:09 pmColumbia Regional
$384
Find similar
American Airlines
Sep 17
COU12:28 pmColumbia Regional
7h 09m
1 stop
CLT8:37 pmCharlotte Douglas
Sep 21
CLT7:21 amCharlotte Douglas
5h 39m
1 stop
COU12:00 pmColumbia Regional
$400
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Tue 9/2

12:17 pm-8:25 pm

1 stop7h 08m

Charlotte Douglas

Sat 9/6

1:36 pm-6:44 pm

1 stop6h 08m

$378

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Tue 9/2

12:17 pm-6:22 pm

1 stop5h 05m

Charlotte Douglas

Sat 9/6

8:00 am-1:09 pm

2 stops6h 09m

$384

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Wed 9/17

12:28 pm-8:37 pm

1 stop7h 09m

Charlotte Douglas

Sun 9/21

7:21 am-12:00 pm

1 stop5h 39m

$400

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Tue 9/23

6:24 am-3:31 pm

2 stops8h 07m

Myrtle Beach Intl

Tue 9/30

5:52 pm-10:45 pm

1 stop5h 53m

$416

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Tue 9/23

4:23 pm-10:51 pm

1 stop5h 28m

Myrtle Beach Intl

Tue 9/30

5:52 pm-10:45 pm

1 stop5h 53m

$420

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Tue 9/23

6:24 am-3:31 pm

2 stops8h 07m

Myrtle Beach Intl

Tue 9/30

8:06 am-4:44 pm

2 stops9h 38m

$421

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Tue 9/2

6:15 am-12:26 pm

1 stop5h 11m

Knoxville McGhee Tyson

Sat 9/6

4:37 pm-10:45 pm

1 stop7h 08m

$430

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Tue 9/2

6:15 am-5:47 pm

2 stops10h 32m

Knoxville McGhee Tyson

Sat 9/6

7:29 am-11:58 am

1 stop5h 29m

$436

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Tue 9/2

6:15 am-5:47 pm

2 stops10h 32m

Knoxville McGhee Tyson

Sat 9/6

6:25 am-1:09 pm

2 stops7h 44m

$441

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Wed 9/3

4:23 pm-10:51 pm

1 stop5h 28m

Myrtle Beach Intl

Sun 9/7

7:00 am-12:00 pm

1 stop6h 00m

$469

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to North Carolina from

How to get the cheapest flight ticket from Columbia, Missouri to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to North Carolina?

The cheapest day to depart from Columbia, Missouri to North Carolina is on a Friday when prices can be found for as low as $401. The most expensive day to fly to North Carolina is Thursday, with ticket prices averaging around $590.

What is the cheapest time of day to depart on your flight to North Carolina?

The cheapest time of day to fly to North Carolina is in the afternoon when flights can be purchased for as low as $519. Try not to purchase tickets in the morning because they tend to be around $538. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Columbia, Missouri to North Carolina flights?

You could potentially save up to 32% on your flight if you consider stops on a Columbia, Missouri to North Carolina flight.

Cheap Columbia, Missouri to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to North Carolina

Direct flights

None
There are no direct flights from Columbia, Missouri to North Carolina. There are no popular flight routes from Columbia, Missouri to North Carolina.
Search flight deals

  • When did momondo last update prices for flights from Columbia Regional Airport to North Carolina?

    Prices for flights from Columbia Regional Airport to North Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to North Carolina?

  • How old do you have to be to fly from Columbia Regional Airport to North Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to North Carolina.

  • What documentation or ID do you need to fly to North Carolina?

    The required travel and health documents for your North Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at North Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbia, Missouri to North Carolina

Compare and see reviews for airlines that fly from Columbia, Missouri to North Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $320Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to North Carolina?

It is quick and easy to find Columbia to North Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to North Carolina that suits you.

Can I find flights from Columbia to North Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Columbia to North Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Columbia to North Carolina?

Once all potential Columbia to North Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Columbia to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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