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Cheap flights from Columbia, Missouri to North Carolina from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to North Carolina departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia, Missouri to North Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:10 pm - 8:52 pm
COU
-
TYS
4h 42m1 stop
United Airlines Logo
11:10 am - 2:35 pm
TYS
-
COU
4h 25m1 stop
$298United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
3:10 pm - 8:52 pm
COU
-
TYS
4h 42m1 stop
United Airlines Logo
2:25 pm - 9:37 pm
TYS
-
COU
8h 12m2 stops
$304United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
8:45 am - 11:44 pm
COU
-
TYS
13h 59m2 stops
United Airlines Logo
2:25 pm - 9:37 pm
TYS
-
COU
8h 12m2 stops
$309United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
11:17 am - 5:06 pm
COU
-
ORF
4h 49m1 stop
United Airlines Logo
10:05 am - 2:35 pm
ORF
-
COU
5h 30m1 stop
$328United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
11:17 am - 4:52 pm
COU
-
AVL
4h 35m1 stop
United Airlines Logo
5:29 pm - 9:37 pm
AVL
-
COU
5h 08m1 stop
$328United Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
3:16 pm - 9:23 pm
COU
-
CLT
5h 07m1 stop
United Airlines Logo
10:30 am - 2:29 pm
CLT
-
COU
4h 59m1 stop
$330United Airlines
Wed, May 6 - Wed, May 20
United Airlines Logo
11:17 am - 5:06 pm
COU
-
ORF
4h 49m1 stop
United Airlines Logo
12:25 pm - 9:37 pm
ORF
-
COU
10h 12m2 stops
$334United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
3:10 pm - 9:03 pm
COU
-
AVL
4h 53m1 stop
United Airlines Logo
10:20 am - 8:33 pm
AVL
-
COU
11h 13m2 stops
$334United Airlines
Sat, Jan 31 - Tue, Feb 3
American Airlines Logo
5:57 am - 11:31 am
COU
-
CLT
4h 34m1 stop
American Airlines Logo
9:20 am - 2:38 pm
CLT
-
COU
6h 18m1 stop
$374American Airlines
Wed, May 6 - Wed, May 20
American Airlines Logo
10:09 am - 7:10 pm
COU
-
CLT
8h 01m1 stop
American Airlines Logo
10:41 pm - 9:39 am
CLT
-
COU
11h 58m1 stop
$486American Airlines
Wed, Dec 31 - Sun, Jan 4

United Airlines flights from Columbia, Missouri to North Carolina

Our best United Airlines deals on Columbia, Missouri to North Carolina flight tickets
United Airlines
Jan 24
COU3:10 pmColumbia Regional
4h 42m
1 stop
TYS8:52 pmKnoxville McGhee Tyson
Jan 28
TYS11:10 amKnoxville McGhee Tyson
4h 25m
1 stop
COU2:35 pmColumbia Regional
$298
Find similar
United Airlines
Jan 24
COU11:17 amColumbia Regional
11h 27m
2 stops
TYS11:44 pmKnoxville McGhee Tyson
Jan 28
TYS11:10 amKnoxville McGhee Tyson
4h 25m
1 stop
COU2:35 pmColumbia Regional
$304
Find similar
United Airlines
Jan 24
COU8:09 amColumbia Regional
10h 41m
2 stops
TYS7:50 pmKnoxville McGhee Tyson
Jan 28
TYS2:25 pmKnoxville McGhee Tyson
8h 12m
2 stops
COU9:37 pmColumbia Regional
$309
Find similar

American Airlines flights from Columbia, Missouri to North Carolina

Our best American Airlines deals on Columbia, Missouri to North Carolina flight tickets
American Airlines
May 6
COU5:57 amColumbia Regional
4h 34m
1 stop
CLT11:31 amCharlotte Douglas
May 20
CLT9:20 amCharlotte Douglas
6h 18m
1 stop
COU2:38 pmColumbia Regional
$374
Find similar
American Airlines
Dec 23
COU3:20 pmColumbia Regional
7h 26m
1 stop
CLT11:46 pmCharlotte Douglas
Dec 27
CLT6:00 pmCharlotte Douglas
4h 59m
1 stop
COU9:59 pmColumbia Regional
$418
Find similar
American Airlines
Dec 31
COU7:35 amColumbia Regional
7h 21m
1 stop
TYS3:56 pmKnoxville McGhee Tyson
Jan 4
TYS7:48 amKnoxville McGhee Tyson
12h 24m
1 stop
COU7:12 pmColumbia Regional
$477
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 1/24

3:10 pm-8:52 pm

1 stop4h 42m

Knoxville McGhee Tyson

Wed 1/28

11:10 am-2:35 pm

1 stop4h 25m

$298

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 1/24

3:10 pm-8:52 pm

1 stop4h 42m

Knoxville McGhee Tyson

Wed 1/28

2:25 pm-9:37 pm

2 stops8h 12m

$304

ColumbiaKnoxville

COU - TYS

COUTYS

Columbia Regional

Sat 1/24

8:45 am-11:44 pm

2 stops13h 59m

Knoxville McGhee Tyson

Wed 1/28

2:25 pm-9:37 pm

2 stops8h 12m

$309

ColumbiaNorfolk

COU - ORF

COUORF

Columbia Regional

Sat 1/17

11:17 am-5:06 pm

1 stop4h 49m

Norfolk

Wed 1/21

10:05 am-2:35 pm

1 stop5h 30m

$328

ColumbiaAsheville

COU - AVL

COUAVL

Columbia Regional

Sat 1/31

11:17 am-4:52 pm

1 stop4h 35m

Asheville Regional

Tue 2/3

5:29 pm-9:37 pm

1 stop5h 08m

$328

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Wed 5/6

3:16 pm-9:23 pm

1 stop5h 07m

Charlotte Douglas

Wed 5/20

10:30 am-2:29 pm

1 stop4h 59m

$330

ColumbiaNorfolk

COU - ORF

COUORF

Columbia Regional

Sat 1/17

11:17 am-5:06 pm

1 stop4h 49m

Norfolk

Wed 1/21

12:25 pm-9:37 pm

2 stops10h 12m

$334

ColumbiaAsheville

COU - AVL

COUAVL

Columbia Regional

Sat 1/31

3:10 pm-9:03 pm

1 stop4h 53m

Asheville Regional

Tue 2/3

10:20 am-8:33 pm

2 stops11h 13m

$334

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Wed 5/6

5:57 am-11:31 am

1 stop4h 34m

Charlotte Douglas

Wed 5/20

9:20 am-2:38 pm

1 stop6h 18m

$374

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Wed 12/31

10:09 am-7:10 pm

1 stop8h 01m

Charlotte Douglas

Sun 1/4

10:41 pm-9:39 am

1 stop11h 58m

$486

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to North Carolina from

How to get the cheapest flight ticket from Columbia, Missouri to North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to North Carolina?

The cheapest day to depart from Columbia, Missouri to North Carolina is on a Friday when prices can be found for as low as $555. The most expensive day to fly to North Carolina is Monday, with ticket prices averaging around $733.

What is the cheapest time of day to depart on your flight to North Carolina?

The cheapest time of day to fly to North Carolina is in the afternoon when flights can be purchased for as low as $580. Try not to purchase tickets in the morning because they tend to be around $590. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Columbia, Missouri to North Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a Columbia, Missouri to North Carolina flight.

Cheap Columbia, Missouri to North Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to North Carolina

Fastest flight time

4h 35m

Direct flights

None
The fastest flight from Columbia, Missouri to North Carolina takes 4h 35m
There are no direct flights from Columbia, Missouri to North Carolina. There are no popular flight routes from Columbia, Missouri to North Carolina.
Search flight deals

  • When did momondo last update prices for flights from Columbia Regional Airport to North Carolina?

    Prices for flights from Columbia Regional Airport to North Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to North Carolina?

  • How old do you have to be to fly from Columbia Regional Airport to North Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to North Carolina.

  • What documentation or ID do you need to fly to North Carolina?

    The required travel and health documents for your North Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at North Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Columbia, Missouri to North Carolina

Compare and see reviews for airlines that fly from Columbia, Missouri to North Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $404Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to North Carolina?

It is quick and easy to find Columbia to North Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to North Carolina that suits you.

Can I find flights from Columbia to North Carolina with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Columbia to North Carolina flights to just show those with flexible booking policies.

How can momondo help me find flights from Columbia to North Carolina?

Once all potential Columbia to North Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to North Carolina right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Columbia to North Carolina flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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