Cheap flights from Columbia, Missouri to Myrtle Beach from $255

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to Myrtle Beach departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Columbia, Missouri to Myrtle Beach

Cheap round-trip flights

American Airlines Logo
7:09 am - 4:39 pmCOU-MYR
8h 30m1 stop
American Airlines Logo
5:43 pm - 10:35 pmMYR-COU
5h 52m1 stop
$480American Airlines
Find Deal
Tue, Dec 9 - Sat, Dec 13
American Airlines Logo
7:09 am - 4:39 pmCOU-MYR
8h 30m1 stop
American Airlines Logo
3:57 pm - 10:00 pmMYR-COU
7h 03m2 stops
$486American Airlines
Find Deal
Tue, Dec 9 - Sat, Dec 13
American Airlines Logo
6:40 am - 2:44 pmCOU-MYR
7h 04m2 stops
American Airlines Logo
6:00 am - 1:25 pmMYR-COU
8h 25m2 stops
$491American Airlines
Find Deal
Tue, Dec 9 - Sat, Dec 13

American Airlines flights from Columbia, Missouri to Myrtle Beach

Our best American Airlines deals on Columbia, Missouri to Myrtle Beach flight tickets
American Airlines
Sep 3
COU4:23 pmColumbia Regional
5h 28m
1 stop
MYR10:51 pmMyrtle Beach Intl
Sep 7
MYR7:00 amMyrtle Beach Intl
6h 00m
1 stop
COU12:00 pmColumbia Regional
American Airlines
Sep 3
COU12:28 pmColumbia Regional
9h 37m
2 stops
MYR11:05 pmMyrtle Beach Intl
Sep 7
MYR7:00 amMyrtle Beach Intl
6h 00m
1 stop
COU12:00 pmColumbia Regional
American Airlines
Dec 9
COU7:09 amColumbia Regional
8h 30m
1 stop
MYR4:39 pmMyrtle Beach Intl
Dec 13
MYR5:43 pmMyrtle Beach Intl
5h 52m
1 stop
COU10:35 pmColumbia Regional

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Tue 12/9

7:09 am-4:39 pm

1 stop8h 30m

Myrtle Beach Intl

Sat 12/13

5:43 pm-10:35 pm

1 stop5h 52m

$480

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Tue 12/9

7:09 am-4:39 pm

1 stop8h 30m

Myrtle Beach Intl

Sat 12/13

3:57 pm-10:00 pm

2 stops7h 03m

$486

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Tue 12/9

6:40 am-2:44 pm

2 stops7h 04m

Myrtle Beach Intl

Sat 12/13

6:00 am-1:25 pm

2 stops8h 25m

$491

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sat 11/15

7:09 am-4:41 pm

1 stop8h 32m

$255

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sat 11/15

6:34 am-3:23 pm

2 stops7h 49m

$261

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sat 11/15

7:09 am-4:41 pm

1 stop8h 32m

$378

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sat 11/15

7:09 am-7:22 pm

2 stops11h 13m

$384

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from Columbia, Missouri to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Columbia Regional to Myrtle Beach Intl?

American Airlines is the most popular carrier operating from Columbia Regional to Myrtle Beach Intl

When to book flights from Columbia, Missouri to Myrtle Beach

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to Myrtle Beach according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to Myrtle Beach (COU to MYR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to Myrtle Beach

Direct flights

None
There are no direct flights from Columbia, Missouri to Myrtle Beach. There are no popular flight routes from Columbia, Missouri to Myrtle Beach.
  • How far is Columbia Regional to Myrtle Beach Intl by plane?

    Columbia Regional and Myrtle Beach Intl are 830.5 mi apart from one another. In terms of flight time, this usually takes a little over 7h 04m.

  • When did momondo last update prices for flights from Columbia Regional Airport to Myrtle Beach Intl Airport?

    Prices for flights from Columbia Regional Airport to Myrtle Beach Intl Airport refresh daily.

  • How old do you have to be to fly from Columbia Regional Airport to Myrtle Beach Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The necessary travel and health documents for your Myrtle Beach Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Surfside Beach
Garden City Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Myrtle Beach?

It is quick and easy to find Columbia to Myrtle Beach flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Myrtle Beach that suits you.

Can I find flights from Columbia to Myrtle Beach with flexible booking policies on momondo?

All flight searches from Columbia to Myrtle Beach on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Columbia to Myrtle Beach?

momondo helps you find the best flight between Columbia and Myrtle Beach by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Columbia to Myrtle Beach right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Myrtle Beach from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Tue 9/2
Tue 9/9

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