What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Cleveland according to our data. Delta is the first choice among our users, with 31% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 7 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Cleveland Hopkins Intl to South America?

Spirit Airlines, Air Canada, and Avianca are the most popular carriers operating from Cleveland Hopkins Intl to South America

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South America?

Prices for flights from Cleveland Hopkins Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South America?

The number of operators available for flights from Cleveland Hopkins Intl Airport to South America is 5 as of January 2026.

How old do you have to be to fly from Cleveland Hopkins Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$169 Cheap Flights from Cleveland to South America in 2026

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Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

7:10 pm - 1:10 pm

CLE

CTG

18h 00m

1 stop

2:21 pm - 2:03 pm

CTG

CLE

23h 42m

1 stop

$292Multiple Airlines

Sat, Feb 21 - Wed, Feb 25

7:04 pm - 1:10 pm

CLE

CTG

18h 06m

1 stop

2:21 pm - 1:42 am

CTG

CLE

11h 21m

1 stop

$304Multiple Airlines

Fri, Feb 27 - Fri, Mar 6

7:04 pm - 12:10 pm

CLE

CTG

18h 06m

1 stop

1:21 pm - 1:42 am

CTG

CLE

11h 21m

1 stop

$310Multiple Airlines

Mon, Mar 9 - Thu, Mar 12

7:10 pm - 1:10 pm

CLE

CTG

18h 00m

1 stop

2:21 pm - 7:34 am

CTG

CLE

17h 13m

2 stops

$315Multiple Airlines

Sat, Feb 21 - Wed, Feb 25

6:26 pm - 12:19 pm

CLE

CTG

18h 53m

1 stop

1:24 pm - 11:28 pm

CTG

CLE

9h 04m

1 stop

$316Multiple Airlines

Sun, Mar 15 - Tue, Mar 17

7:02 pm - 1:55 pm

CLE

MDE

18h 53m

2 stops

2:50 pm - 6:09 pm

MDE

CLE

27h 19m

2 stops

$405Spirit Airlines

Tue, Feb 10 - Tue, Feb 17

7:59 pm - 10:20 am

CLE

GRU

13h 21m

1 stop

9:30 pm - 9:50 am

GRU

CLE

13h 20m

1 stop

$781Copa Airlines

Thu, Mar 12 - Sat, Mar 21

5:30 pm - 7:40 am

CLE

SCL

12h 10m

1 stop

11:30 pm - 11:43 am

SCL

CLE

14h 13m

1 stop

$821LATAM Airlines

Wed, Feb 18 - Mon, Mar 2

12:35 pm - 6:55 am

CLE

SCL

16h 20m

1 stop

11:30 pm - 11:43 am

SCL

CLE

14h 13m

1 stop

$822LATAM Airlines

Fri, Feb 20 - Wed, Mar 4

11:56 am - 10:15 am

CLE

EZE

21h 19m

1 stop

8:10 pm - 10:05 am

EZE

CLE

14h 55m

1 stop

$1,047Delta

Tue, Mar 24 - Mon, Apr 6

Avianca flights from Cleveland to South America

Our best Avianca deals on Cleveland to South America flight tickets

Avianca

Mar 31

CLE11:00 amCleveland Hopkins Intl

10h 25m

1 stop

BOG8:25 pmBogotá El Dorado

Apr 7

BOG7:00 amBogotá El Dorado

12h 38m

1 stop

CLE8:38 pmCleveland Hopkins Intl

$448

Avianca

Apr 11

CLE7:05 amCleveland Hopkins Intl

16h 21m

2 stops

CTG10:26 pmCartagena Rafael Nunez

Apr 18

CTG6:06 amCartagena Rafael Nunez

12h 43m

2 stops

CLE7:49 pmCleveland Hopkins Intl

$492

Avianca

Feb 21

CLE6:06 pmCleveland Hopkins Intl

17h 34m

2 stops

CTG11:40 amCartagena Rafael Nunez

Feb 25

CTG6:00 amCartagena Rafael Nunez

14h 08m

2 stops

CLE8:08 pmCleveland Hopkins Intl

$501

Copa Airlines flights from Cleveland to South America

Our best Copa Airlines deals on Cleveland to South America flight tickets

Copa Airlines

Feb 27

CLE9:00 amCleveland Hopkins Intl

14h 00m

2 stops

CTG11:00 pmCartagena Rafael Nunez

Mar 6

CTG9:42 amCartagena Rafael Nunez

24h 08m

2 stops

CLE9:50 amCleveland Hopkins Intl

$548

Copa Airlines

May 10

CLE9:00 amCleveland Hopkins Intl

15h 01m

2 stops

CTG11:01 pmCartagena Rafael Nunez

May 16

CTG3:05 pmCartagena Rafael Nunez

17h 43m

2 stops

CLE9:48 amCleveland Hopkins Intl

$568

Copa Airlines

Jan 27

CLE7:55 pmCleveland Hopkins Intl

13h 30m

2 stops

BOG9:25 amBogotá El Dorado

Feb 3

BOG4:45 amBogotá El Dorado

15h 55m

2 stops

CLE8:40 pmCleveland Hopkins Intl

$575

Fly from

Fly to

Route

Depart

Return

Price

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sat 2/21

7:10 pm-1:10 pm

1 stop18h 00m

Cartagena Rafael Nunez

Wed 2/25

2:21 pm-2:03 pm

1 stop23h 42m

$292

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Fri 2/27

7:04 pm-1:10 pm

1 stop18h 06m

Cartagena Rafael Nunez

Fri 3/6

2:21 pm-1:42 am

1 stop11h 21m

$304

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Mon 3/9

7:04 pm-12:10 pm

1 stop18h 06m

Cartagena Rafael Nunez

Thu 3/12

1:21 pm-1:42 am

1 stop11h 21m

$310

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sat 2/21

7:10 pm-1:10 pm

1 stop18h 00m

Cartagena Rafael Nunez

Wed 2/25

2:21 pm-7:34 am

2 stops17h 13m

$315

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sun 3/15

6:26 pm-12:19 pm

1 stop18h 53m

Cartagena Rafael Nunez

Tue 3/17

1:24 pm-11:28 pm

1 stop9h 04m

$316

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 2/10

7:02 pm-1:55 pm

2 stops18h 53m

Medellín Jose Maria Cordova Intl

Tue 2/17

2:50 pm-6:09 pm

2 stops27h 19m

$405

ClevelandSao Paulo

CLE - GRU

CLEGRU

Cleveland Hopkins Intl

Thu 3/12

7:59 pm-10:20 am

1 stop13h 21m

Sao Paulo Guarulhos Intl

Sat 3/21

9:30 pm-9:50 am

1 stop13h 20m

$781

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Wed 2/18

5:30 pm-7:40 am

1 stop12h 10m

Santiago Arturo Merino Benitez

Mon 3/2

11:30 pm-11:43 am

1 stop14h 13m

$821

ClevelandSantiago

CLE - SCL

CLESCL

Cleveland Hopkins Intl

Fri 2/20

12:35 pm-6:55 am

1 stop16h 20m

Santiago Arturo Merino Benitez

Wed 3/4

11:30 pm-11:43 am

1 stop14h 13m

$822

ClevelandBuenos Aires

CLE - EZE

CLEEZE

Cleveland Hopkins Intl

Tue 3/24

11:56 am-10:15 am

1 stop21h 19m

Buenos Aires Ministro Pistarini

Mon 4/6

8:10 pm-10:05 am

1 stop14h 55m

$1,047

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Cleveland to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from Cleveland to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $684. If you aren’t able to travel during the month of October, then book flights to South America from Cleveland during January instead. Flights to South America in January, while not as cheap as those in October, still average around $701.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Cleveland when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $823 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Cleveland for as low as $692 on momondo.

Can stopping save me money on Cleveland to South America flights?

You could potentially save up to 5% on your flight if you consider stops on a Cleveland to South America flight.

Cheap Cleveland to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to South America

Fastest flight time	7h 10m
Direct flights	None

The fastest flight from Cleveland to South America takes 7h 10m

There are no direct flights from Cleveland to South America. There are no popular flight routes from Cleveland to South America.

Search flight deals

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South America?
Prices for flights from Cleveland Hopkins Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South America?
The number of operators available for flights from Cleveland Hopkins Intl Airport to South America is 5 as of January 2026.
How old do you have to be to fly from Cleveland Hopkins Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Cleveland to South America

Compare and see reviews for airlines that fly from Cleveland to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $413	Free Cancellation	Rating 7.9 8,048 reviews	Search Delta flights
United Airlines	PriceFrom $462	Free Cancellation	Rating 7.4 9,163 reviews	Search United Airlines flights
American Airlines	PriceFrom $469	Free Cancellation	Rating 7.2 11,130 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $498	Free Cancellation	Rating 7.5 1,904 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $536	Free Cancellation	Rating 7.6 1,559 reviews	Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Cleveland to South America for you.

Can I find flights from Cleveland to South America with flexible booking policies on momondo?

Flights from Cleveland to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Cleveland to South America?

Once you have performed a search for Cleveland to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cleveland to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Cleveland and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $188

Flights to Buenos Airesfrom $491

Flights to Sao Paulofrom $356

Flights to Bogotáfrom $165

Flights to Rio de Janeirofrom $378

Flights to Medellínfrom $181

Flights to Santiagofrom $320

Flights to Cartagenafrom $178

Flights to Quitofrom $232

Flights to Cuscofrom $369

Flights to Guayaquilfrom $178

Flights to Califrom $168

Cheap flights from Cleveland to South America from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to South America departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

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Price Alerts

Find the cheapest flights from Cleveland to South America

Cheap round-trip flights

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Avianca flights from Cleveland to South America

Our best Avianca deals on Cleveland to South America flight tickets

Copa Airlines flights from Cleveland to South America

Our best Copa Airlines deals on Cleveland to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Cleveland to South America that are best for you.

How to get the cheapest flight ticket from Cleveland to South America

What is the cheapest month to fly to South America?

How far in advance should I book a flight to South America?

Can stopping save me money on Cleveland to South America flights?

You could potentially save up to 5% on your flight if you consider stops on a Cleveland to South America flight.

What is the cheapest airline that flies from Cleveland Hopkins Intl to South America?

Spirit Airlines, Air Canada, and Avianca are the most popular carriers operating from Cleveland Hopkins Intl to South America

What airlines fly to South America?

Cheap Cleveland to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to South America

Fastest flight time

Direct flights

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South America?

How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South America?

How old do you have to be to fly from Cleveland Hopkins Intl Airport to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Cleveland to South America

Compare and see reviews for airlines that fly from Cleveland to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to South America?

Can I find flights from Cleveland to South America with flexible booking policies on momondo?

How can momondo help me find flights from Cleveland to South America?

I’m not ready to book a flight from Cleveland to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo