What is the cheapest airline that flies from Cleveland Hopkins Intl to South America?

American Airlines, United Airlines, and Air Canada are the most popular carriers operating from Cleveland Hopkins Intl to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Cleveland according to our data. Delta is the first choice among our users, with 38% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South America?

Prices for flights from Cleveland Hopkins Intl Airport to South America are updated daily.

How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South America?

The number of operators available for flights from Cleveland Hopkins Intl Airport to South America is 6 as of July 2026.

How old do you have to be to fly from Cleveland Hopkins Intl Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$208 Cheap Flights from Cleveland to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Cleveland to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 12:52 pm

CLE

CTG

6h 52m

1 stop

2:00 pm - 11:12 pm

CTG

CLE

8h 12m

1 stop

$375JetBlue

Mon, Sep 21 - Thu, Sep 24

7:00 am - 12:52 pm

CLE

CTG

6h 52m

1 stop

2:00 pm - 11:12 pm

CTG

CLE

8h 12m

1 stop

$377JetBlue

Mon, Sep 14 - Thu, Sep 17

6:17 am - 12:35 pm

CLE

CTG

7h 18m

1 stop

1:35 pm - 11:46 pm

CTG

CLE

9h 11m

1 stop

$387American Airlines

Sat, Sep 26 - Tue, Sep 29

7:47 pm - 3:14 pm

CLE

CTG

19h 27m

2 stops

2:34 pm - 11:55 pm

CTG

CLE

9h 21m

1 stop

$392American Airlines

Sun, Nov 8 - Tue, Nov 17

6:51 pm - 9:10 pm

CLE

MDE

27h 19m

1 stop

9:45 am - 10:22 pm

MDE

CLE

11h 37m

1 stop

$446United Airlines

Thu, Oct 1 - Mon, Oct 5

10:15 am - 12:15 am

CLE

MDE

15h 00m

2 stops

11:15 pm - 12:29 am

MDE

CLE

24h 14m

2 stops

$450LATAM Airlines

Tue, Aug 25 - Thu, Aug 27

6:51 pm - 9:10 pm

CLE

MDE

27h 19m

1 stop

9:45 am - 11:09 am

MDE

CLE

24h 24m

1 stop

$455United Airlines

Fri, Oct 16 - Mon, Oct 26

7:05 am - 9:25 pm

CLE

MDE

15h 20m

2 stops

7:05 am - 12:29 am

MDE

CLE

16h 24m

2 stops

$481LATAM Airlines

Wed, Aug 26 - Sun, Aug 30

6:55 pm - 5:10 am

CLE

LIM

11h 15m

1 stop

8:00 am - 6:17 pm

LIM

CLE

34h 17m

2 stops

$620Air Canada

Sat, Oct 31 - Sat, Nov 7

6:55 pm - 3:15 am

CLE

LIM

33h 20m

2 stops

8:00 am - 6:17 pm

LIM

CLE

34h 17m

2 stops

$623Air Canada

Sat, Oct 31 - Sat, Nov 7

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American Airlines flights from Cleveland to South America

Our best American Airlines deals on Cleveland to South America flight tickets

American Airlines

Sep 26

CLE6:17 amCleveland Hopkins Intl

7h 18m

1 stop

CTG12:35 pmCartagena Rafael Nunez

Sep 29

CTG1:35 pmCartagena Rafael Nunez

9h 11m

1 stop

CLE11:46 pmCleveland Hopkins Intl

$387

American Airlines

Nov 8

CLE7:47 pmCleveland Hopkins Intl

19h 27m

2 stops

CTG3:14 pmCartagena Rafael Nunez

Nov 17

CTG2:34 pmCartagena Rafael Nunez

9h 21m

1 stop

CLE11:55 pmCleveland Hopkins Intl

$392

American Airlines

Nov 8

CLE5:09 pmCleveland Hopkins Intl

22h 05m

1 stop

CTG3:14 pmCartagena Rafael Nunez

Nov 17

CTG2:34 pmCartagena Rafael Nunez

9h 21m

1 stop

CLE11:55 pmCleveland Hopkins Intl

$397

LATAM Airlines flights from Cleveland to South America

Our best LATAM Airlines deals on Cleveland to South America flight tickets

LATAM Airlines

Aug 25

CLE10:15 amCleveland Hopkins Intl

13h 20m

2 stops

MDE10:35 pmMedellín Jose Maria Cordova Intl

Aug 27

MDE5:10 amMedellín Jose Maria Cordova Intl

12h 49m

2 stops

CLE6:59 pmCleveland Hopkins Intl

$450

LATAM Airlines

Aug 26

CLE7:05 amCleveland Hopkins Intl

15h 20m

2 stops

MDE9:25 pmMedellín Jose Maria Cordova Intl

Aug 30

MDE7:05 amMedellín Jose Maria Cordova Intl

16h 24m

2 stops

CLE12:29 amCleveland Hopkins Intl

$481

LATAM Airlines

Oct 18

CLE7:05 amCleveland Hopkins Intl

15h 25m

2 stops

MDE9:30 pmMedellín Jose Maria Cordova Intl

Oct 28

MDE9:45 amMedellín Jose Maria Cordova Intl

14h 03m

2 stops

CLE12:48 amCleveland Hopkins Intl

$548

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Mon 9/21

7:00 am-12:52 pm

1 stop6h 52m

Cartagena Rafael Nunez

Thu 9/24

2:00 pm-11:12 pm

1 stop8h 12m

$375

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Mon 9/14

7:00 am-12:52 pm

1 stop6h 52m

Cartagena Rafael Nunez

Thu 9/17

2:00 pm-11:12 pm

1 stop8h 12m

$377

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sat 9/26

6:17 am-12:35 pm

1 stop7h 18m

Cartagena Rafael Nunez

Tue 9/29

1:35 pm-11:46 pm

1 stop9h 11m

$387

ClevelandCartagena

CLE - CTG

CLECTG

Cleveland Hopkins Intl

Sun 11/8

7:47 pm-3:14 pm

2 stops19h 27m

Cartagena Rafael Nunez

Tue 11/17

2:34 pm-11:55 pm

1 stop9h 21m

$392

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Thu 10/1

6:51 pm-9:10 pm

1 stop27h 19m

Medellín Jose Maria Cordova Intl

Mon 10/5

9:45 am-10:22 pm

1 stop11h 37m

$446

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 8/25

10:15 am-12:15 am

2 stops15h 00m

Medellín Jose Maria Cordova Intl

Thu 8/27

11:15 pm-12:29 am

2 stops24h 14m

$450

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Fri 10/16

6:51 pm-9:10 pm

1 stop27h 19m

Medellín Jose Maria Cordova Intl

Mon 10/26

9:45 am-11:09 am

1 stop24h 24m

$455

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Wed 8/26

7:05 am-9:25 pm

2 stops15h 20m

Medellín Jose Maria Cordova Intl

Sun 8/30

7:05 am-12:29 am

2 stops16h 24m

$481

ClevelandLima

CLE - LIM

CLELIM

Cleveland Hopkins Intl

Sat 10/31

6:55 pm-5:10 am

1 stop11h 15m

Lima J Chavez Intl

Sat 11/7

8:00 am-6:17 pm

2 stops34h 17m

$620

ClevelandLima

CLE - LIM

CLELIM

Cleveland Hopkins Intl

Sat 10/31

6:55 pm-3:15 am

2 stops33h 20m

Lima J Chavez Intl

Sat 11/7

8:00 am-6:17 pm

2 stops34h 17m

$623

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Cleveland to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from Cleveland to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $670. If you aren’t able to travel during the month of April, then book flights to South America from Cleveland during February instead. Flights to South America in February, while not as cheap as those in April, still average around $729.

How far in advance should I book a flight from Cleveland to South America?

You are more likely to see cheaper flights to South America from Cleveland when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $835 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Cleveland for as low as $627 on momondo.

Can stopping save me money on Cleveland to South America flights?

You could potentially save up to 11% on your flight if you consider stops on a Cleveland to South America flight.

Cheap Cleveland to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to South America

Fastest flight time	6h 52m
Direct flights	None

The fastest flight from Cleveland to South America takes 6h 52m

There are no direct flights from Cleveland to South America. There are no popular flight routes from Cleveland to South America.

Search flight deals

Frequently asked questions about flying from Cleveland to South America

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to South America?
Prices for flights from Cleveland Hopkins Intl Airport to South America are updated daily.
How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to South America?
The number of operators available for flights from Cleveland Hopkins Intl Airport to South America is 6 as of July 2026.
How old do you have to be to fly from Cleveland Hopkins Intl Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Cleveland to South America

Compare and see reviews for airlines that fly from Cleveland to South America with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $310	Free Cancellation	Rating 7.1 11,823 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $498	Free Cancellation	Rating 7.4 1,959 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $536	Free Cancellation	Rating 7.6 1,565 reviews	Search Copa Airlines flights
Air Canada	PriceFrom $553	Free Cancellation	Rating 7.1 11,360 reviews	Search Air Canada flights
Delta	PriceFrom $582	Free Cancellation	Rating 7.8 8,477 reviews	Search Delta flights
United Airlines	PriceFrom $783	Free Cancellation	Rating 7.4 10,011 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Cleveland to South America for you.

Can I find flights from Cleveland to South America with flexible booking policies on momondo?

Flights from Cleveland to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Cleveland to South America?

Once you have performed a search for Cleveland to South America flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cleveland to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Cleveland and alert you when they change.