Cheap flights from Chicago to Syracuse from $106

The month of January is, on average, the cheapest month to fly to Syracuse from Chicago, with most prices found around $286. If you aren’t able to travel to Syracuse during the month of January, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $295.

The cheapest day to depart from Chicago to Syracuse is on a Saturday. Travelers who choose to depart for Syracuse on a Saturday will often find tickets for as low as $289. The most expensive day to fly to Syracuse is Monday, with ticket prices averaging around $466.

Our most recent data shows that the best time of day to fly to Syracuse is in the evening. Flights from Chicago to Syracuse during this time can be as low as $307. Flights to Syracuse are more costly at noon, with an average ticket price of $394. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Chicago O'Hare Intl to Syracuse Hancock Intl for the best Chicago - Syracuse Hancock Intl flight prices

You are more likely to see cheaper flights to Syracuse from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Syracuse for around $360 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Syracuse from Chicago for as low as $209 on momondo.

There are 4 cabin classes available to choose from on Chicago to Syracuse flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

JetBlue, Delta, and Allegiant Air are the most popular carriers operating from Chicago to Syracuse Hancock Intl

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Syracuse from Chicago according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Syracuse. Keep in mind that there are 3 different airlines that fly to Syracuse on a routine basis, so you have a few additional options to choose from.

The number of flights available between Chicago and Syracuse is 20 per day as of July 2026. The most frequent departure time is 1:00PM, with 58% of daily flights leaving in the afternoon.

142 flights are operational weekly from Chicago to Syracuse as of July 2026. The most popular departure day for this route is Mon, with 17% of flights per week taking off on this day.