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Cheap flights from Charlotte to South America from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to South America departing on 2/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:00 am - 1:15 pm
CLT
-
CTG
7h 15m1 stop
Spirit Airlines Logo
2:21 pm - 12:40 am
CTG
-
CLT
10h 19m1 stop
$249Spirit Airlines
mar., ene. 20 - mar., feb. 3
Spirit Airlines Logo
1:24 pm - 12:21 am
CLT
-
GYE
10h 57m1 stop
Spirit Airlines Logo
1:26 am - 6:48 pm
GYE
-
CLT
17h 22m1 stop
$256Spirit Airlines
jue., ene. 29 - sáb., feb. 7
Multiple Airlines Logo
7:43 pm - 12:21 am
CLT
-
GYE
28h 38m1 stop
Multiple Airlines Logo
1:26 am - 9:17 pm
GYE
-
CLT
19h 51m1 stop
$273Multiple Airlines
vie., ene. 9 - dom., ene. 25
Multiple Airlines Logo
7:43 pm - 12:21 am
CLT
-
GYE
28h 38m1 stop
Multiple Airlines Logo
1:26 am - 8:58 pm
GYE
-
CLT
19h 32m1 stop
$279Multiple Airlines
vie., ene. 9 - jue., ene. 29
Delta Logo
11:45 am - 8:09 pm
CLT
-
UIO
9h 24m1 stop
Delta Logo
11:20 pm - 8:38 am
UIO
-
CLT
8h 18m1 stop
$534Delta
lun., abr. 13 - jue., abr. 23
Delta Logo
4:52 pm - 4:58 am
CLT
-
UIO
13h 06m2 stops
Delta Logo
11:20 pm - 5:34 pm
UIO
-
CLT
17h 14m1 stop
$538Delta
dom., abr. 12 - mar., abr. 28
United Airlines Logo
6:23 am - 11:25 pm
CLT
-
UIO
18h 02m1 stop
United Airlines Logo
12:35 am - 10:56 am
UIO
-
CLT
9h 21m1 stop
$544United Airlines
vie., abr. 10 - lun., abr. 27
United Airlines Logo
6:30 am - 11:25 pm
CLT
-
UIO
17h 55m2 stops
United Airlines Logo
12:35 am - 5:07 pm
UIO
-
CLT
15h 32m2 stops
$549United Airlines
vie., abr. 10 - lun., abr. 27
GOL Logo
2:42 pm - 10:45 am
CLT
-
SDU
18h 03m2 stops
GOL Logo
6:00 am - 9:21 pm
SDU
-
CLT
16h 21m2 stops
$658GOL
jue., mar. 5 - jue., mar. 12
GOL Logo
6:45 pm - 10:50 am
CLT
-
SDU
15h 05m2 stops
GOL Logo
6:00 am - 9:35 pm
SDU
-
CLT
16h 35m2 stops
$680GOL
jue., abr. 23 - lun., abr. 27

Spirit Airlines flights from Charlotte to South America

Our best Spirit Airlines deals on Charlotte to South America flight tickets
Spirit Airlines
Jan 20
CLT6:00 amCharlotte Douglas
7h 15m
1 stop
CTG1:15 pmCartagena Rafael Nunez
Feb 3
CTG2:21 pmCartagena Rafael Nunez
10h 19m
1 stop
CLT12:40 amCharlotte Douglas
$249
Find similar
Spirit Airlines
Jan 29
CLT1:24 pmCharlotte Douglas
10h 57m
1 stop
GYE12:21 amGuayaquil Jose Joaquin de Olmedo
Feb 7
GYE1:26 amGuayaquil Jose Joaquin de Olmedo
17h 22m
1 stop
CLT6:48 pmCharlotte Douglas
$256
Find similar
Spirit Airlines
Jan 28
CLT6:00 amCharlotte Douglas
8h 15m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Jan 31
MDE3:15 pmMedellín Jose Maria Cordova Intl
9h 25m
1 stop
CLT12:40 amCharlotte Douglas
$264
Find similar

LATAM Airlines flights from Charlotte to South America

Our best LATAM Airlines deals on Charlotte to South America flight tickets
LATAM Airlines
Apr 14
CLT11:45 amCharlotte Douglas
9h 24m
1 stop
UIO8:09 pmQuito Mariscal Sucr
Apr 23
UIO11:20 pmQuito Mariscal Sucr
8h 18m
1 stop
CLT8:38 amCharlotte Douglas
$554
Find similar
LATAM Airlines
Feb 5
CLT7:59 amCharlotte Douglas
27h 46m
2 stops
UIO11:45 amQuito Mariscal Sucr
Mar 1
UIO11:45 pmQuito Mariscal Sucr
18h 27m
1 stop
CLT6:12 pmCharlotte Douglas
$570
Find similar
LATAM Airlines
Apr 13
CLT11:45 amCharlotte Douglas
9h 24m
1 stop
UIO8:09 pmQuito Mariscal Sucr
Apr 27
UIO11:20 pmQuito Mariscal Sucr
8h 18m
1 stop
CLT8:38 amCharlotte Douglas
$587
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 11, 2025.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

mar. 1/20

6:00 am-1:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

mar. 2/3

2:21 pm-12:40 am

1 stop10h 19m

$249

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

jue. 1/29

1:24 pm-12:21 am

1 stop10h 57m

Guayaquil Jose Joaquin de Olmedo

sáb. 2/7

1:26 am-6:48 pm

1 stop17h 22m

$256

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

vie. 1/9

7:43 pm-12:21 am

1 stop28h 38m

Guayaquil Jose Joaquin de Olmedo

dom. 1/25

1:26 am-9:17 pm

1 stop19h 51m

$273

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

vie. 1/9

7:43 pm-12:21 am

1 stop28h 38m

Guayaquil Jose Joaquin de Olmedo

jue. 1/29

1:26 am-8:58 pm

1 stop19h 32m

$279

CharlotteQuito

CLT - UIO

CLTUIO

Charlotte Douglas

lun. 4/13

11:45 am-8:09 pm

1 stop9h 24m

Quito Mariscal Sucr

jue. 4/23

11:20 pm-8:38 am

1 stop8h 18m

$534

CharlotteQuito

CLT - UIO

CLTUIO

Charlotte Douglas

dom. 4/12

4:52 pm-4:58 am

2 stops13h 06m

Quito Mariscal Sucr

mar. 4/28

11:20 pm-5:34 pm

1 stop17h 14m

$538

CharlotteQuito

CLT - UIO

CLTUIO

Charlotte Douglas

vie. 4/10

6:23 am-11:25 pm

1 stop18h 02m

Quito Mariscal Sucr

lun. 4/27

12:35 am-10:56 am

1 stop9h 21m

$544

CharlotteQuito

CLT - UIO

CLTUIO

Charlotte Douglas

vie. 4/10

6:30 am-11:25 pm

2 stops17h 55m

Quito Mariscal Sucr

lun. 4/27

12:35 am-5:07 pm

2 stops15h 32m

$549

CharlotteRio de Janeiro

CLT - SDU

CLTSDU

Charlotte Douglas

jue. 3/5

2:42 pm-10:45 am

2 stops18h 03m

Rio de Janeiro Santos Dumont

jue. 3/12

6:00 am-9:21 pm

2 stops16h 21m

$658

CharlotteRio de Janeiro

CLT - SDU

CLTSDU

Charlotte Douglas

jue. 4/23

6:45 pm-10:50 am

2 stops15h 05m

Rio de Janeiro Santos Dumont

lun. 4/27

6:00 am-9:35 pm

2 stops16h 35m

$680

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Charlotte to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Charlotte to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $676. If you aren’t able to travel during the month of November, then book flights to South America from Charlotte during October instead. Flights to South America in October, while not as cheap as those in November, still average around $720.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Charlotte to South America is on a Tuesday when prices can be found for as low as $616. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Charlotte to South America for around $888.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Charlotte to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $685. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $874 on average. Flights to South America from Charlotte in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $762 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Charlotte for as low as $689 on momondo.

Can stopping save me money on Charlotte to South America flights?

You could potentially save up to 5% on your flight if you consider stops on a Charlotte to South America flight.

Cheap Charlotte to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to South America

Fastest flight time

6h 50m

Direct flights

None
The fastest flight from Charlotte to South America takes 6h 50m
There are no direct flights from Charlotte to South America. There are no popular flight routes from Charlotte to South America.
Search flight deals

  • When did momondo last update prices for flights from Charlotte Douglas Airport to South America?

    Prices for flights from Charlotte Douglas Airport to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to South America?

  • How old do you have to be to fly from Charlotte Douglas Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to South America

Compare and see reviews for airlines that fly from Charlotte to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $247Free CancellationRating
6.3
8,180 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $394Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights
American AirlinesPriceFrom $436Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights
DeltaPriceFrom $452Free CancellationRating
7.9
8,007 reviews
Search Delta flights
LATAM AirlinesPriceFrom $470Free CancellationRating
7.5
1,887 reviews
Search LATAM Airlines flights
GOLPriceFrom $667Free CancellationRating
7.3
1,127 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to South America for you.

Can I find flights from Charlotte to South America with flexible booking policies on momondo?

Flights from Charlotte to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to South America?

momondo provides multiple filters to help you find the best flight to South America from Charlotte. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charlotte to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charlotte to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

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sáb. 1/10
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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
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Flights to Califrom $180