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Cheap flights from Charlotte to South America from $106

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to South America departing on 9/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charlotte to South America

Cheap round-trip flights

Spirit Airlines Logo
6:00 am - 1:10 pmCLT-BOG
8h 10m1 stop
Spirit Airlines Logo
2:05 pm - 9:22 amBOG-CLT
18h 17m1 stop
$264Spirit Airlines
Find Deal
Wed, Sep 17 - Sun, Sep 21
Spirit Airlines Logo
7:00 am - 11:54 pmCLT-MDE
17h 54m1 stop
Spirit Airlines Logo
2:20 pm - 11:55 pmMDE-CLT
8h 35m1 stop
$264Spirit Airlines
Find Deal
Mon, Aug 25 - Thu, Aug 28
American Airlines Logo
7:20 pm - 7:10 pmCLT-GYE
24h 50m1 stop
American Airlines Logo
6:00 am - 11:48 pmGYE-CLT
17h 48m1 stop
$522American Airlines
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Tue, Oct 28 - Fri, Nov 21
American Airlines Logo
5:16 am - 12:25 pmCLT-CTG
8h 09m1 stop
American Airlines Logo
1:25 pm - 11:50 pmCTG-CLT
9h 25m1 stop
$526American Airlines
Find Deal
Wed, Oct 15 - Wed, Oct 22
Delta Logo
8:16 am - 10:50 pmCLT-CTG
15h 34m2 stops
Delta Logo
5:05 am - 9:28 pmCTG-CLT
15h 23m2 stops
$534Delta
Find Deal
Tue, Oct 21 - Sun, Oct 26
LATAM Airlines Logo
5:05 pm - 5:00 amCLT-LIM
12h 55m1 stop
LATAM Airlines Logo
12:15 pm - 11:50 pmLIM-CLT
11h 35m1 stop
$563LATAM Airlines
Find Deal
Tue, Oct 28 - Thu, Nov 6
LATAM Airlines Logo
7:00 am - 8:15 pmCLT-LIM
13h 15m2 stops
LATAM Airlines Logo
12:15 pm - 11:54 pmLIM-CLT
11h 39m1 stop
$573LATAM Airlines
Find Deal
Wed, Nov 19 - Tue, Dec 2
GOL Logo
5:20 pm - 5:35 pmCLT-GIG
23h 15m2 stops
GOL Logo
6:15 pm - 11:32 pmGIG-CLT
30h 17m2 stops
$624GOL
Find Deal
Tue, Sep 9 - Wed, Sep 17
GOL Logo
2:30 pm - 10:10 amCLT-GIG
18h 40m2 stops
GOL Logo
3:40 pm - 9:45 pmGIG-CLT
31h 05m2 stops
$627GOL
Find Deal
Tue, Sep 9 - Fri, Sep 19
Delta Logo
11:45 am - 6:10 amCLT-SCL
16h 25m1 stop
Delta Logo
6:30 pm - 11:03 amSCL-CLT
18h 33m2 stops
$754Delta
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Wed, Dec 10 - Wed, Dec 17

Spirit Airlines flights from Charlotte to South America

Our best Spirit Airlines deals on Charlotte to South America flight tickets
Spirit Airlines
Sep 17
CLT6:00 amCharlotte Douglas
8h 10m
1 stop
BOG1:10 pmBogotá El Dorado
Sep 21
BOG2:05 pmBogotá El Dorado
18h 17m
1 stop
CLT9:22 amCharlotte Douglas
$264
Find similar
Spirit Airlines
Sep 12
CLT3:34 pmCharlotte Douglas
9h 51m
1 stop
MDE12:25 amMedellín Jose Maria Cordova Intl
Sep 19
MDE2:09 pmMedellín Jose Maria Cordova Intl
18h 13m
1 stop
CLT9:22 amCharlotte Douglas
$272
Find similar
Spirit Airlines
Sep 22
CLT5:45 amCharlotte Douglas
8h 25m
1 stop
BOG1:10 pmBogotá El Dorado
Sep 28
BOG2:05 pmBogotá El Dorado
18h 17m
1 stop
CLT9:22 amCharlotte Douglas
$274
Find similar

LATAM Airlines flights from Charlotte to South America

Our best LATAM Airlines deals on Charlotte to South America flight tickets
LATAM Airlines
Oct 28
CLT5:05 pmCharlotte Douglas
12h 55m
1 stop
LIM5:00 amLima J Chavez Intl
Nov 6
LIM12:15 pmLima J Chavez Intl
11h 35m
1 stop
CLT11:50 pmCharlotte Douglas
$563
Find similar
LATAM Airlines
Nov 19
CLT7:00 amCharlotte Douglas
13h 15m
2 stops
LIM8:15 pmLima J Chavez Intl
Dec 2
LIM12:15 pmLima J Chavez Intl
11h 39m
1 stop
CLT11:54 pmCharlotte Douglas
$573
Find similar
LATAM Airlines
Nov 5
CLT6:45 amCharlotte Douglas
13h 30m
2 stops
LIM8:15 pmLima J Chavez Intl
Nov 12
LIM11:40 pmLima J Chavez Intl
11h 23m
1 stop
CLT11:03 amCharlotte Douglas
$584
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 9/17

6:00 am-1:10 pm

1 stop8h 10m

Bogotá El Dorado

Sun 9/21

2:05 pm-9:22 am

1 stop18h 17m

$264

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 8/25

7:00 am-11:54 pm

1 stop17h 54m

Medellín Jose Maria Cordova Intl

Thu 8/28

2:20 pm-11:55 pm

1 stop8h 35m

$264

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 10/28

7:20 pm-7:10 pm

1 stop24h 50m

Guayaquil Jose Joaquin de Olmedo

Fri 11/21

6:00 am-11:48 pm

1 stop17h 48m

$522

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Wed 10/15

5:16 am-12:25 pm

1 stop8h 09m

Cartagena Rafael Nunez

Wed 10/22

1:25 pm-11:50 pm

1 stop9h 25m

$526

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Tue 10/21

8:16 am-10:50 pm

2 stops15h 34m

Cartagena Rafael Nunez

Sun 10/26

5:05 am-9:28 pm

2 stops15h 23m

$534

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

Tue 10/28

5:05 pm-5:00 am

1 stop12h 55m

Lima J Chavez Intl

Thu 11/6

12:15 pm-11:50 pm

1 stop11h 35m

$563

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

Wed 11/19

7:00 am-8:15 pm

2 stops13h 15m

Lima J Chavez Intl

Tue 12/2

12:15 pm-11:54 pm

1 stop11h 39m

$573

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Tue 9/9

5:20 pm-5:35 pm

2 stops23h 15m

Rio de Janeiro–Galeão Intl

Wed 9/17

6:15 pm-11:32 pm

2 stops30h 17m

$624

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Tue 9/9

2:30 pm-10:10 am

2 stops18h 40m

Rio de Janeiro–Galeão Intl

Fri 9/19

3:40 pm-9:45 pm

2 stops31h 05m

$627

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 12/10

11:45 am-6:10 am

1 stop16h 25m

Santiago Arturo Merino Benitez

Wed 12/17

6:30 pm-11:03 am

2 stops18h 33m

$754

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Charlotte to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, March is the cheapest month to fly from Charlotte to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $703. If you aren’t able to travel during the month of March, then book flights to South America from Charlotte during October instead. Flights to South America in October, while not as cheap as those in March, still average around $707.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Charlotte to South America is on a Tuesday when prices can be found for as low as $616. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Charlotte to South America for around $888.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Charlotte to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $685. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $874 on average. Flights to South America from Charlotte in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $774 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Charlotte for as low as $695 on momondo.

Can stopping save me money on Charlotte to South America flights?

You could potentially save up to 7% on your flight if you consider stops on a Charlotte to South America flight.

Cheap Charlotte to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to South America

Best Price Found

$106

Fastest flight time

6h 20m

Direct flights

None

Airports in South America

5 airports
The best one-way flight to South America from Charlotte in the past 72 hours is $106. The best round-trip flight deal from Charlotte to South America found on momondo in the last 72 hours is $264.
The fastest flight from Charlotte to South America takes 6h 20m
There are no direct flights from Charlotte to South America. Popular non-direct routes for this connection are Charlotte Douglas Airport - Cartagena Rafael Nunez Airport, Charlotte Douglas Airport - Bogotá El Dorado Airport and Charlotte Douglas Airport - Medellín Jose Maria Cordova Intl Airport.
There are 5 airports near South America: Lima J Chavez Intl (LIM), Guayaquil Jose Joaquin de Olmedo (GYE), Cartagena Rafael Nunez (CTG), Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE)
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  • When did momondo last update prices for flights from Charlotte Douglas Airport to South America?

    Prices for flights from Charlotte Douglas Airport to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to South America?

  • How old do you have to be to fly from Charlotte Douglas Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to South America

Compare and see reviews for airlines that fly from Charlotte to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $247Free CancellationRating
6.3
8,054 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $384Free CancellationRating
7.4
8,904 reviews
Search United Airlines flights
DeltaPriceFrom $425Free CancellationRating
8.0
7,983 reviews
Search Delta flights
American AirlinesPriceFrom $449Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $469Free CancellationRating
7.5
1,823 reviews
Search LATAM Airlines flights
GOLPriceFrom $579Free CancellationRating
7.3
1,091 reviews
Search GOL flights
Air CanadaPriceFrom $704Free CancellationRating
7.1
9,855 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to South America for you.

Can I find flights from Charlotte to South America with flexible booking policies on momondo?

Flights from Charlotte to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to South America?

momondo provides multiple filters to help you find the best flight to South America from Charlotte. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charlotte to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charlotte to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $300
Flights to Buenos Airesfrom $565
Flights to Bogotáfrom $177
Flights to Sao Paulofrom $348
Flights to Medellínfrom $167
Flights to Rio de Janeirofrom $421
Flights to Santiagofrom $380
Flights to Cartagenafrom $178
Flights to Quitofrom $318
Flights to Califrom $178
Flights to Cuscofrom $413
Flights to Guayaquilfrom $231