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Cheap flights from Charlotte to South America from $75

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charlotte to South America departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:00 am - 1:13 pm
CLT
-
MDE
8h 13m
1 stop
Spirit Airlines Logo
2:10 pm - 12:40 am
MDE
-
CLT
9h 30m
1 stop
$214Spirit Airlines
Wed, Apr 29 - Wed, May 27
Spirit Airlines Logo
5:55 am - 2:13 pm
CLT
-
MDE
8h 18m
1 stop
Spirit Airlines Logo
2:15 pm - 11:56 pm
MDE
-
CLT
8h 41m
1 stop
$223Spirit Airlines
Sat, Mar 7 - Wed, Mar 11
Spirit Airlines Logo
5:55 am - 2:13 pm
CLT
-
MDE
8h 18m
1 stop
Spirit Airlines Logo
2:15 pm - 11:56 pm
MDE
-
CLT
8h 41m
1 stop
$228Spirit Airlines
Mon, Mar 2 - Mon, Mar 9
Spirit Airlines Logo
7:13 pm - 12:47 pm
CLT
-
BOG
17h 34m
2 stops
Spirit Airlines Logo
3:06 pm - 8:26 am
BOG
-
CLT
17h 20m
1 stop
$236Spirit Airlines
Wed, Feb 18 - Mon, Feb 23
Spirit Airlines Logo
6:00 am - 1:22 pm
CLT
-
MDE
8h 22m
1 stop
Spirit Airlines Logo
2:17 pm - 12:38 am
MDE
-
CLT
9h 21m
1 stop
$236Spirit Airlines
Wed, Mar 18 - Wed, Mar 25
Spirit Airlines Logo
6:00 am - 1:11 pm
CLT
-
BOG
8h 11m
1 stop
Spirit Airlines Logo
2:10 pm - 12:38 am
BOG
-
CLT
9h 28m
1 stop
$237Spirit Airlines
Wed, Mar 18 - Wed, Mar 25
Multiple Airlines Logo
4:29 pm - 9:35 pm
CLT
-
LIM
30h 06m
1 stop
Multiple Airlines Logo
10:30 pm - 2:18 pm
LIM
-
CLT
14h 48m
1 stop
$316Multiple Airlines
Sat, Apr 11 - Thu, Apr 23
GOL Logo
1:15 pm - 6:25 am
CLT
-
GIG
16h 10m
2 stops
GOL Logo
5:55 am - 10:59 pm
GIG
-
CLT
18h 04m
2 stops
$679GOL
Sun, Mar 8 - Fri, Mar 13
GOL Logo
4:30 pm - 6:35 am
CLT
-
GIG
37h 05m
2 stops
GOL Logo
10:30 pm - 9:30 pm
GIG
-
CLT
24h 00m
2 stops
$682GOL
Tue, May 19 - Sun, May 24
GOL Logo
2:42 pm - 6:15 pm
CLT
-
GIG
26h 33m
2 stops
GOL Logo
5:55 am - 10:59 pm
GIG
-
CLT
18h 04m
2 stops
$694GOL
Sun, Mar 8 - Fri, Mar 13

Spirit Airlines flights from Charlotte to South America

Our best Spirit Airlines deals on Charlotte to South America flight tickets
Spirit Airlines
Apr 29
CLT6:00 amCharlotte Douglas
8h 13m
1 stop
MDE1:13 pmMedellín Jose Maria Cordova Intl
May 27
MDE2:10 pmMedellín Jose Maria Cordova Intl
9h 30m
1 stop
CLT12:40 amCharlotte Douglas
$214
Spirit Airlines
Mar 7
CLT5:55 amCharlotte Douglas
8h 18m
1 stop
MDE2:13 pmMedellín Jose Maria Cordova Intl
Mar 11
MDE2:15 pmMedellín Jose Maria Cordova Intl
8h 41m
1 stop
CLT11:56 pmCharlotte Douglas
$223
Spirit Airlines
Mar 22
CLT6:00 amCharlotte Douglas
8h 22m
1 stop
MDE1:22 pmMedellín Jose Maria Cordova Intl
Mar 24
MDE2:17 pmMedellín Jose Maria Cordova Intl
9h 21m
1 stop
CLT12:38 amCharlotte Douglas
$228

United Airlines flights from Charlotte to South America

Our best United Airlines deals on Charlotte to South America flight tickets
United Airlines
May 11
CLT7:43 pmCharlotte Douglas
28h 42m
2 stops
UIO11:25 pmQuito Mariscal Sucr
May 31
UIO7:25 amQuito Mariscal Sucr
13h 26m
1 stop
CLT9:51 pmCharlotte Douglas
$559
United Airlines
May 9
CLT6:35 amCharlotte Douglas
17h 50m
1 stop
UIO11:25 pmQuito Mariscal Sucr
Jun 1
UIO7:25 amQuito Mariscal Sucr
25h 24m
2 stops
CLT9:49 amCharlotte Douglas
$560
United Airlines
May 21
CLT7:10 amCharlotte Douglas
17h 15m
1 stop
UIO11:25 pmQuito Mariscal Sucr
Jun 3
UIO12:35 amQuito Mariscal Sucr
43h 54m
2 stops
CLT9:29 pmCharlotte Douglas
$566

momondo Fare Finder

 
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 4/29

6:00 am-1:13 pm

1 stop8h 13m

Medellín Jose Maria Cordova Intl

Wed 5/27

2:10 pm-12:40 am

1 stop9h 30m

$214

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 3/7

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Wed 3/11

2:15 pm-11:56 pm

1 stop8h 41m

$223

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/2

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Mon 3/9

2:15 pm-11:56 pm

1 stop8h 41m

$228

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 2/18

7:13 pm-12:47 pm

2 stops17h 34m

Bogotá El Dorado

Mon 2/23

3:06 pm-8:26 am

1 stop17h 20m

$236

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 3/18

6:00 am-1:22 pm

1 stop8h 22m

Medellín Jose Maria Cordova Intl

Wed 3/25

2:17 pm-12:38 am

1 stop9h 21m

$236

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 3/18

6:00 am-1:11 pm

1 stop8h 11m

Bogotá El Dorado

Wed 3/25

2:10 pm-12:38 am

1 stop9h 28m

$237

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

Sat 4/11

4:29 pm-9:35 pm

1 stop30h 06m

Lima J Chavez Intl

Thu 4/23

10:30 pm-2:18 pm

1 stop14h 48m

$316

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Sun 3/8

1:15 pm-6:25 am

2 stops16h 10m

Rio de Janeiro–Galeão Intl

Fri 3/13

5:55 am-10:59 pm

2 stops18h 04m

$679

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Tue 5/19

4:30 pm-6:35 am

2 stops37h 05m

Rio de Janeiro–Galeão Intl

Sun 5/24

10:30 pm-9:30 pm

2 stops24h 00m

$682

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Sun 3/8

2:42 pm-6:15 pm

2 stops26h 33m

Rio de Janeiro–Galeão Intl

Fri 3/13

5:55 am-10:59 pm

2 stops18h 04m

$694

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Charlotte to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Charlotte to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $676. If you aren’t able to travel during the month of November, then book flights to South America from Charlotte during October instead. Flights to South America in October, while not as cheap as those in November, still average around $720.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $764 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Charlotte for as low as $689 on momondo.

Can stopping save me money on Charlotte to South America flights?

You could potentially save up to 32% on your flight if you consider stops on a Charlotte to South America flight.

Cheap Charlotte to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charlotte to South America

Fastest flight time

7h 15m

Direct flights

None
The fastest flight from Charlotte to South America takes 7h 15m
There are no direct flights from Charlotte to South America. There are no popular flight routes from Charlotte to South America.
Search flight deals

  • When did momondo last update prices for flights from Charlotte Douglas Airport to South America?

    Prices for flights from Charlotte Douglas Airport to South America are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charlotte Douglas Airport to South America?

  • How old do you have to be to fly from Charlotte Douglas Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charlotte Douglas Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Charlotte to South America

Compare and see reviews for airlines that fly from Charlotte to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $121Free CancellationRating
6.3
8,409 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $424Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
American AirlinesPriceFrom $435Free CancellationRating
7.2
11,218 reviews
Search American Airlines flights
DeltaPriceFrom $452Free CancellationRating
7.9
8,139 reviews
Search Delta flights
LATAM AirlinesPriceFrom $487Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights
GOLPriceFrom $667Free CancellationRating
7.3
1,165 reviews
Search GOL flights

Why use momondo?

Why should I use momondo to find a flight deal from Charlotte to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Charlotte to South America for you.

Can I find flights from Charlotte to South America with flexible booking policies on momondo?

Flights from Charlotte to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charlotte to South America?

momondo provides multiple filters to help you find the best flight to South America from Charlotte. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charlotte to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charlotte to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo
Flights to Limafrom $187
Flights to Buenos Airesfrom $503
Flights to Sao Paulofrom $377
Flights to Bogotáfrom $162
Flights to Rio de Janeirofrom $474
Flights to Medellínfrom $94
Flights to Santiagofrom $371
Flights to Cartagenafrom $166
Flights to Quitofrom $295
Flights to Guayaquilfrom $165
Flights to Cuscofrom $320
Flights to Califrom $187