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Cheap flights from Charleston to St. Louis from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to St. Louis departing on 2/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charleston to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:01 pm - 11:33 pm
CHS
-
STL
9h 32m1 stop
Multiple Airlines Logo
5:42 pm - 8:38 am
STL
-
CHS
13h 56m1 stop
$173Multiple Airlines
Tue, Jan 27 - Sat, Jan 31
Multiple Airlines Logo
3:01 pm - 11:33 pm
CHS
-
STL
9h 32m1 stop
Multiple Airlines Logo
8:22 pm - 4:10 pm
STL
-
CHS
18h 48m2 stops
$195Multiple Airlines
Tue, Jan 27 - Sat, Jan 31
Multiple Airlines Logo
3:01 pm - 10:34 pm
CHS
-
STL
8h 33m1 stop
Multiple Airlines Logo
8:32 pm - 4:10 pm
STL
-
CHS
18h 38m2 stops
$232Multiple Airlines
Tue, Jan 13 - Wed, Jan 14
Multiple Airlines Logo
10:18 pm - 10:33 pm
CHS
-
STL
25h 15m2 stops
Multiple Airlines Logo
5:11 pm - 8:38 am
STL
-
CHS
14h 27m1 stop
$240Multiple Airlines
Mon, Jan 5 - Mon, Jan 12
Multiple Airlines Logo
5:05 pm - 11:33 pm
CHS
-
STL
31h 28m2 stops
Multiple Airlines Logo
5:42 pm - 8:43 am
STL
-
CHS
14h 01m1 stop
$254Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
3:21 pm - 10:33 pm
CHS
-
STL
8h 12m1 stop
Multiple Airlines Logo
8:32 pm - 4:10 pm
STL
-
CHS
18h 38m2 stops
$255Multiple Airlines
Mon, Jan 12 - Wed, Jan 14
Multiple Airlines Logo
2:59 pm - 10:33 pm
CHS
-
STL
8h 34m1 stop
Multiple Airlines Logo
10:57 am - 9:23 pm
STL
-
CHS
33h 26m2 stops
$258Multiple Airlines
Tue, Dec 16 - Sun, Dec 21
Multiple Airlines Logo
3:01 pm - 10:23 am
CHS
-
STL
20h 22m1 stop
Multiple Airlines Logo
5:42 pm - 8:43 am
STL
-
CHS
14h 01m1 stop
$264Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
3:01 pm - 10:34 pm
CHS
-
STL
8h 33m1 stop
Multiple Airlines Logo
5:11 pm - 8:38 am
STL
-
CHS
14h 27m1 stop
$277Multiple Airlines
Tue, Jan 13 - Wed, Jan 14
Delta Logo
3:02 pm - 8:06 pm
CHS
-
STL
6h 04m1 stop
Delta Logo
6:25 am - 2:22 pm
STL
-
CHS
6h 57m1 stop
$290Delta
Mon, Jan 12 - Wed, Jan 14

Delta flights from Charleston to St. Louis

Our best Delta deals on Charleston to St. Louis flight tickets
Delta
Jan 12
CHS3:02 pmCharleston
6h 04m
1 stop
STL8:06 pmLambert-St Louis
Jan 14
STL6:25 amLambert-St Louis
6h 57m
1 stop
CHS2:22 pmCharleston
$290
Find similar
Delta
Feb 13
CHS2:58 pmCharleston
6h 11m
1 stop
STL8:09 pmLambert-St Louis
Feb 17
STL7:10 amLambert-St Louis
5h 54m
1 stop
CHS2:04 pmCharleston
$365
Find similar
Delta
Dec 19
CHS10:40 amCharleston
6h 26m
1 stop
STL4:06 pmLambert-St Louis
Dec 25
STL7:00 amLambert-St Louis
5h 56m
1 stop
CHS1:56 pmCharleston
$542
Find similar

Southwest flights from Charleston to St. Louis

Our best Southwest deals on Charleston to St. Louis flight tickets
Southwest
Jan 5
CHS6:15 amCharleston
3h 55m
1 stop
STL9:10 amLambert-St Louis
Jan 7
STL8:15 amLambert-St Louis
3h 35m
1 stop
CHS12:50 pmCharleston
$333
Find similar
Southwest
Jan 7
CHS7:55 amCharleston
8h 05m
2 stops
STL3:00 pmLambert-St Louis
Jan 14
STL9:00 amLambert-St Louis
9h 10m
2 stops
CHS7:10 pmCharleston
$357
Find similar
Southwest
Jan 5
CHS10:40 amCharleston
8h 00m
2 stops
STL5:40 pmLambert-St Louis
Jan 7
STL10:15 amLambert-St Louis
6h 20m
2 stops
CHS5:35 pmCharleston
$371
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 1/27

3:01 pm-11:33 pm

1 stop9h 32m

Lambert-St Louis

Sat 1/31

5:42 pm-8:38 am

1 stop13h 56m

$173

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 1/27

3:01 pm-11:33 pm

1 stop9h 32m

Lambert-St Louis

Sat 1/31

8:22 pm-4:10 pm

2 stops18h 48m

$195

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 1/13

3:01 pm-10:34 pm

1 stop8h 33m

Lambert-St Louis

Wed 1/14

8:32 pm-4:10 pm

2 stops18h 38m

$232

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Mon 1/5

10:18 pm-10:33 pm

2 stops25h 15m

Lambert-St Louis

Mon 1/12

5:11 pm-8:38 am

1 stop14h 27m

$240

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 1/22

5:05 pm-11:33 pm

2 stops31h 28m

Lambert-St Louis

Thu 1/29

5:42 pm-8:43 am

1 stop14h 01m

$254

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Mon 1/12

3:21 pm-10:33 pm

1 stop8h 12m

Lambert-St Louis

Wed 1/14

8:32 pm-4:10 pm

2 stops18h 38m

$255

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 12/16

2:59 pm-10:33 pm

1 stop8h 34m

Lambert-St Louis

Sun 12/21

10:57 am-9:23 pm

2 stops33h 26m

$258

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 1/22

3:01 pm-10:23 am

1 stop20h 22m

Lambert-St Louis

Thu 1/29

5:42 pm-8:43 am

1 stop14h 01m

$264

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 1/13

3:01 pm-10:34 pm

1 stop8h 33m

Lambert-St Louis

Wed 1/14

5:11 pm-8:38 am

1 stop14h 27m

$277

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Mon 1/12

3:02 pm-8:06 pm

1 stop6h 04m

Lambert-St Louis

Wed 1/14

6:25 am-2:22 pm

1 stop6h 57m

$290

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Charleston to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, September is the cheapest month to fly from Charleston to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $308. The month of August is another great option to travel to St. Louis, with average flight prices from Charleston averaging around $342.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $336. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $646. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Charleston in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $388 when looking at flights departing in the afternoon. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $606 per ticket.

What is the cheapest Charleston to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best Charleston - Lambert-St Louis flight prices

What cabin class options are available on Charleston to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on Charleston to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charleston to St. Louis flights?

No. A direct flight is the cheapest option for a flight between Charleston to St. Louis.

How have Charleston to St. Louis flight prices changed over time?

As of December 2025, prices for Charleston to St. Louis flights are approximately 91% more expensive when compared to flights at the same time last year.

When to book flights from Charleston to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to St. Louis (CHS to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to St. Louis

Fastest flight time

4h 44m

Direct flights

Sat and Sun

Airports in St. Louis

1 airport
The fastest flight from Charleston to St. Louis takes 4h 44m
Direct flights go from Charleston to St. Louis on Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport near St. Louis: Lambert-St Louis (STL)
Search flight deals

  • How far is Charleston to Lambert-St Louis by plane?

    A flight from Charleston to Lambert-St Louis will travel around 702.5 mi. A reasonable flight in good conditions will take 3h 55m.

  • When did momondo last update prices for flights from Charleston Airport to Lambert-St Louis Airport?

    Prices for flights from Charleston Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Charleston Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Charleston to St. Louis?

  • What is the most popular airline from Charleston to St. Louis?

Best airlines flying from Charleston to St. Louis

Compare and see reviews for airlines that fly from Charleston to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $287Free CancellationRating
8.0
4,254 reviews
Search Southwest flights
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
DeltaPriceFrom $306Free CancellationRating
7.9
8,011 reviews
Search Delta flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
Fenton
Wentzville
St. Peters
Collinsville
Alton
Farmington
Festus
Clayton
Glencoe
Edwardsville
Eureka
Litchfield
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to St. Louis with flexible booking policies on momondo?

All flight searches from Charleston to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Charleston to St. Louis?

Once you have performed a search for Charleston to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to St. Louis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to St. Louis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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