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Cheap flights from Charleston to St. Louis from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to St. Louis departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:13 pm - 9:29 pm
CHS
-
STL
6h 16m
1 stop
American Airlines Logo
9:23 am - 5:39 pm
STL
-
CHS
7h 16m
1 stop
$227American Airlines
Tue, Jun 9 - Wed, Jun 10
Southwest Logo
2:15 pm - 3:30 pm
CHS
-
STL
2h 15mnonstop
Southwest Logo
3:45 pm - 9:05 pm
STL
-
CHS
4h 20m
1 stop
$233Southwest
Thu, May 21 - Tue, May 26
Multiple Airlines Logo
4:34 pm - 11:57 pm
CHS
-
STL
8h 23m
1 stop
Multiple Airlines Logo
4:19 pm - 8:48 am
STL
-
CHS
15h 29m
1 stop
$236Multiple Airlines
Wed, May 27 - Fri, May 29
American Airlines Logo
7:19 pm - 11:59 pm
CHS
-
STL
5h 40m
1 stop
American Airlines Logo
6:12 pm - 11:48 pm
STL
-
CHS
4h 36m
1 stop
$243American Airlines
Thu, May 21 - Tue, May 26
Multiple Airlines Logo
4:34 pm - 11:57 pm
CHS
-
STL
8h 23m
1 stop
Multiple Airlines Logo
5:27 pm - 12:50 pm
STL
-
CHS
42h 23m
2 stops
$251Multiple Airlines
Wed, May 27 - Mon, Jun 1
Multiple Airlines Logo
7:25 am - 4:15 pm
CHS
-
STL
9h 50m
2 stops
Multiple Airlines Logo
4:19 pm - 9:38 am
STL
-
CHS
16h 19m
1 stop
$252Multiple Airlines
Thu, May 21 - Tue, May 26
United Airlines Logo
11:31 am - 3:46 pm
CHS
-
STL
5h 15m
1 stop
United Airlines Logo
6:00 am - 2:27 pm
STL
-
CHS
7h 27m
2 stops
$256United Airlines
Wed, Jun 17 - Wed, Jun 24
Multiple Airlines Logo
4:34 pm - 11:57 pm
CHS
-
STL
8h 23m
1 stop
Multiple Airlines Logo
4:19 pm - 8:38 am
STL
-
CHS
15h 19m
1 stop
$261Multiple Airlines
Wed, May 27 - Sat, May 30
Southwest Logo
4:15 pm - 10:00 pm
CHS
-
STL
6h 45m
1 stop
Southwest Logo
3:15 pm - 6:15 pm
STL
-
CHS
2h 00mnonstop
$262Southwest
Wed, Jun 17 - Wed, Jun 24
Delta Logo
7:59 pm - 11:59 pm
CHS
-
STL
5h 00m
1 stop
Delta Logo
7:05 am - 12:10 pm
STL
-
CHS
4h 05m
1 stop
$267Delta
Mon, May 18 - Mon, May 25

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United Airlines flights from Charleston to St. Louis

Our best United Airlines deals on Charleston to St. Louis flight tickets
United Airlines
Jun 17
CHS11:31 amCharleston
5h 15m
1 stop
STL3:46 pmLambert-St Louis
Jun 24
STL6:00 amLambert-St Louis
7h 27m
2 stops
CHS2:27 pmCharleston
$256
United Airlines
May 28
CHS11:31 amCharleston
5h 15m
1 stop
STL3:46 pmLambert-St Louis
May 31
STL1:13 pmLambert-St Louis
7h 38m
1 stop
CHS9:51 pmCharleston
$298
United Airlines
Aug 18
CHS3:25 pmCharleston
6h 57m
1 stop
STL9:22 pmLambert-St Louis
Aug 19
STL6:00 amLambert-St Louis
6h 55m
1 stop
CHS1:55 pmCharleston
$307

Southwest flights from Charleston to St. Louis

Our best Southwest deals on Charleston to St. Louis flight tickets
Southwest
May 21
CHS2:15 pmCharleston
2h 15m
STL3:30 pmLambert-St Louis
May 26
STL3:45 pmLambert-St Louis
4h 20m
1 stop
CHS9:05 pmCharleston
$233
Southwest
Jun 17
CHS4:15 pmCharleston
6h 45m
1 stop
STL10:00 pmLambert-St Louis
Jun 24
STL3:15 pmLambert-St Louis
2h 00m
CHS6:15 pmCharleston
$262
Southwest
May 27
CHS3:40 pmCharleston
2h 20m
STL5:00 pmLambert-St Louis
May 29
STL4:00 pmLambert-St Louis
4h 30m
1 stop
CHS9:30 pmCharleston
$273

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 2, 2026.
Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 6/9

4:13 pm-9:29 pm

1 stop6h 16m

Lambert-St Louis

Wed 6/10

9:23 am-5:39 pm

1 stop7h 16m

$227
Quickest round-trip

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 5/21

2:15 pm-3:30 pm

Nonstop2h 15m

Lambert-St Louis

Tue 5/26

3:45 pm-9:05 pm

1 stop4h 20m

$233

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 5/27

4:34 pm-11:57 pm

1 stop8h 23m

Lambert-St Louis

Fri 5/29

4:19 pm-8:48 am

1 stop15h 29m

$236

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 5/21

7:19 pm-11:59 pm

1 stop5h 40m

Lambert-St Louis

Tue 5/26

6:12 pm-11:48 pm

1 stop4h 36m

$243

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 5/27

4:34 pm-11:57 pm

1 stop8h 23m

Lambert-St Louis

Mon 6/1

5:27 pm-12:50 pm

2 stops42h 23m

$251

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 5/21

7:25 am-4:15 pm

2 stops9h 50m

Lambert-St Louis

Tue 5/26

4:19 pm-9:38 am

1 stop16h 19m

$252

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 6/17

11:31 am-3:46 pm

1 stop5h 15m

Lambert-St Louis

Wed 6/24

6:00 am-2:27 pm

2 stops7h 27m

$256

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 5/27

4:34 pm-11:57 pm

1 stop8h 23m

Lambert-St Louis

Sat 5/30

4:19 pm-8:38 am

1 stop15h 19m

$261

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 6/17

4:15 pm-10:00 pm

1 stop6h 45m

Lambert-St Louis

Wed 6/24

3:15 pm-6:15 pm

Nonstop2h 00m

$262

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Mon 5/18

7:59 pm-11:59 pm

1 stop5h 00m

Lambert-St Louis

Mon 5/25

7:05 am-12:10 pm

1 stop4h 05m

$267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Charleston to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and St. Louis?

What is the cheapest month to fly to St. Louis?

In general, February is the cheapest month to fly from Charleston to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $276. The month of September is another great option to travel to St. Louis, with average flight prices from Charleston averaging around $299.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $287. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $606. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Charleston in the morning is the least expensive time of day to depart. momondo users have found prices as low as $373 when looking at flights departing in the morning. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $538 per ticket.

What is the cheapest Charleston to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best Charleston - Lambert-St Louis flight prices

Can stopping save me money on Charleston to St. Louis flights?

No. A direct flight is the cheapest option for a flight between Charleston to St. Louis.

How have Charleston to St. Louis flight prices changed over time?

As of May 2026, prices for Charleston to St. Louis flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Charleston to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to St. Louis (CHS to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to St. Louis

Best Price Found

$179

Fastest flight time

2h 00m

Direct flights

Every day

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Charleston in the past 72 hours is $179. The best round-trip flight deal from Charleston to St. Louis found on momondo in the last 72 hours is $381.
The fastest flight from Charleston to St. Louis takes 2h 00m
Direct flights go from Charleston to St. Louis every day.
There is 1 airport in St. Louis. From Charleston there are direct flights to Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from Charleston to St. Louis

  • How far is Charleston to Lambert-St Louis by plane?

    A flight from Charleston to Lambert-St Louis will travel around 702.5 mi. A reasonable flight in good conditions will take 2h 00m.

  • When did momondo last update prices for flights from Charleston Airport to Lambert-St Louis Airport?

    Prices for flights from Charleston Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Charleston Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Charleston to St. Louis?

  • What is the most popular airline from Charleston to St. Louis?

Best airlines flying from Charleston to St. Louis

Compare and see reviews for airlines that fly from Charleston to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
7.9
8,463 reviews
Search Delta flights
American AirlinesPriceFrom $274Free CancellationRating
7.1
11,674 reviews
Search American Airlines flights
SouthwestPriceFrom $281Free CancellationRating
8.0
4,314 reviews
Search Southwest flights

  • Southwest Flights From Charleston to St. Louis

    Southwest flight deals from Charleston to St. Louis start from $281 round-trip. Over the 1 Southwest flight for this route in a normal week, average airfare is usually $385 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
O'Fallon
Florissant
St. Peters
Collinsville
Wentzville
Alton
Fenton
Farmington
Festus
Clayton
Eureka
Litchfield
Edwardsville
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to St. Louis with flexible booking policies on momondo?

All flight searches from Charleston to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Charleston to St. Louis?

Once you have performed a search for Charleston to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to St. Louis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to St. Louis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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