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Cheap flights from Charleston to St. Louis from $101

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to St. Louis departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
6:45 am - 7:45 amCHS  Charleston-STL Lambert-St Louis
2h 00mnonstop
Southwest Logo
7:20 am - 4:10 pmSTL  Lambert-St Louis-CHS Charleston
7h 50m1 stop Baltimore/Washington
$227Southwest
Sat, Sep 5 - Sun, Sep 6
Multiple Airlines Logo
2:13 pm - 4:34 pmCHS  Charleston-STL Lambert-St Louis
27h 21m1 stop Orlando
Multiple Airlines Logo
2:29 pm - 8:38 amSTL  Lambert-St Louis-CHS Charleston
17h 09m2 stops Atlanta Hartsfield-Jackson Orlando
$228Multiple Airlines
Thu, Sep 24 - Mon, Sep 28
United Airlines Logo
4:58 pm - 10:00 pmCHS  Charleston-STL Lambert-St Louis
6h 02m1 stop Chicago O'Hare Intl
United Airlines Logo
8:40 am - 3:10 pmSTL  Lambert-St Louis-CHS Charleston
5h 30m1 stop Washington, D.C. Dulles Intl
$232United Airlines
Sat, Sep 5 - Sun, Sep 6
Southwest Logo
6:45 am - 7:45 amCHS  Charleston-STL Lambert-St Louis
2h 00mnonstop
Southwest Logo
1:40 pm - 4:40 pmSTL  Lambert-St Louis-CHS Charleston
2h 00mnonstop
$236Southwest
Sat, Sep 5 - Sat, Sep 12
Southwest Logo
6:45 am - 7:45 amCHS  Charleston-STL Lambert-St Louis
2h 00mnonstop
Southwest Logo
3:35 pm - 6:35 pmSTL  Lambert-St Louis-CHS Charleston
2h 00mnonstop
$236Southwest
Sat, Sep 5 - Mon, Sep 7
Multiple Airlines Logo
2:13 pm - 4:34 pmCHS  Charleston-STL Lambert-St Louis
27h 21m1 stop Orlando
Multiple Airlines Logo
2:29 pm - 12:31 pmSTL  Lambert-St Louis-CHS Charleston
21h 02m2 stops Atlanta Hartsfield-Jackson Tampa
$236Multiple Airlines
Thu, Sep 17 - Mon, Sep 21
Delta Logo
7:05 am - 11:15 amCHS  Charleston-STL Lambert-St Louis
5h 10m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:20 pm - 6:05 pmSTL  Lambert-St Louis-CHS Charleston
4h 45m1 stop Atlanta Hartsfield-Jackson
$251Delta
Thu, Nov 26 - Thu, Dec 3
Delta Logo
6:00 am - 9:41 amCHS  Charleston-STL Lambert-St Louis
4h 41m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:31 pm - 8:45 pmSTL  Lambert-St Louis-CHS Charleston
5h 14m1 stop Atlanta Hartsfield-Jackson
$251Delta
Thu, Nov 26 - Wed, Dec 2
American Airlines Logo
2:06 pm - 8:44 pmCHS  Charleston-STL Lambert-St Louis
7h 38m1 stop Chicago O'Hare Intl
American Airlines Logo
5:00 am - 1:16 pmSTL  Lambert-St Louis-CHS Charleston
7h 16m1 stop Chicago O'Hare Intl
$265American Airlines
Thu, Sep 10 - Mon, Sep 14
American Airlines Logo
11:07 am - 5:27 pmCHS  Charleston-STL Lambert-St Louis
7h 20m1 stop Washington, D.C. Reagan-National
American Airlines Logo
1:54 pm - 6:56 pmSTL  Lambert-St Louis-CHS Charleston
4h 02m1 stop Charlotte Douglas
$265American Airlines
Wed, Sep 2 - Wed, Sep 9

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Southwest flights from Charleston to St. Louis

Our best Southwest deals on Charleston to St. Louis flight tickets
Southwest
Sep 5
CHS6:45 amCharleston
2h 00m
STL7:45 amLambert-St Louis
Sep 6
STL7:20 amLambert-St Louis
7h 50m
1 stop
CHS4:10 pmCharleston
$227
Southwest
Sep 5
CHS6:45 amCharleston
2h 00m
STL7:45 amLambert-St Louis
Sep 12
STL1:40 pmLambert-St Louis
2h 00m
CHS4:40 pmCharleston
$236
Southwest
Sep 5
CHS6:45 amCharleston
2h 00m
STL7:45 amLambert-St Louis
Sep 12
STL7:50 amLambert-St Louis
3h 55m
1 stop
CHS12:45 pmCharleston
$241

United Airlines flights from Charleston to St. Louis

Our best United Airlines deals on Charleston to St. Louis flight tickets
United Airlines
Sep 5
CHS4:58 pmCharleston
6h 02m
1 stop
STL10:00 pmLambert-St Louis
Sep 6
STL8:40 amLambert-St Louis
5h 30m
1 stop
CHS3:10 pmCharleston
$232
United Airlines
Sep 5
CHS4:58 pmCharleston
6h 02m
1 stop
STL10:00 pmLambert-St Louis
Sep 6
STL6:00 amLambert-St Louis
8h 10m
2 stops
CHS3:10 pmCharleston
$238
United Airlines
Sep 5
CHS2:54 pmCharleston
9h 05m
2 stops
STL10:59 pmLambert-St Louis
Sep 12
STL8:00 amLambert-St Louis
4h 58m
1 stop
CHS1:58 pmCharleston
$256

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Sat 9/5

6:45 am-7:45 am

Nonstop2h 00m

Lambert-St Louis

Sun 9/6

7:20 am-4:10 pm

1 stop7h 50m

$227

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Thu 9/24

2:13 pm-4:34 pm

1 stop27h 21m

Lambert-St Louis

Mon 9/28

2:29 pm-8:38 am

2 stops17h 09m

$228

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Sat 9/5

4:58 pm-10:00 pm

1 stop6h 02m

Lambert-St Louis

Sun 9/6

8:40 am-3:10 pm

1 stop5h 30m

$232
Quickest round-trip

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Sat 9/5

6:45 am-7:45 am

Nonstop2h 00m

Lambert-St Louis

Sat 9/12

1:40 pm-4:40 pm

Nonstop2h 00m

$236

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Sat 9/5

6:45 am-7:45 am

Nonstop2h 00m

Lambert-St Louis

Mon 9/7

3:35 pm-6:35 pm

Nonstop2h 00m

$236

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Thu 9/17

2:13 pm-4:34 pm

1 stop27h 21m

Lambert-St Louis

Mon 9/21

2:29 pm-12:31 pm

2 stops21h 02m

$236

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Thu 11/26

7:05 am-11:15 am

1 stop5h 10m

Lambert-St Louis

Thu 12/3

12:20 pm-6:05 pm

1 stop4h 45m

$251

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Thu 11/26

6:00 am-9:41 am

1 stop4h 41m

Lambert-St Louis

Wed 12/2

2:31 pm-8:45 pm

1 stop5h 14m

$251

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Thu 9/10

2:06 pm-8:44 pm

1 stop7h 38m

Lambert-St Louis

Mon 9/14

5:00 am-1:16 pm

1 stop7h 16m

$265

CharlestonSt. Louis

CHS Charleston - STL Lambert-St Louis

CHSSTL

Charleston

Wed 9/2

11:07 am-5:27 pm

1 stop7h 20m

Lambert-St Louis

Wed 9/9

1:54 pm-6:56 pm

1 stop4h 02m

$265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Charleston to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and St. Louis?

Prices are currently low for flights on this route.

Typical prices usually range from $321 to $394.
The lowest price recently found on this route was $228.

What is the cheapest month to fly to St. Louis?

In general, February is the cheapest month to fly from Charleston to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $276. The month of May is another great option to travel to St. Louis, with average flight prices from Charleston averaging around $332.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Wednesday when prices can be found for as low as $330. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $606. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Charleston in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $394 when looking at flights departing in the afternoon. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $527 per ticket.

What is the cheapest Charleston to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best Charleston - Lambert-St Louis flight prices

What cabin class options are available on Charleston to St. Louis flights?

There is only 1 cabin class available to choose from on Charleston to St. Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charleston to St. Louis flights?

No. A direct flight is the cheapest option for a flight between Charleston to St. Louis.

How have Charleston to St. Louis flight prices changed over time?

As of August 2026, prices for Charleston to St. Louis flights are approximately 84% more expensive when compared to flights at the same time last year.

When to book flights from Charleston to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to St. Louis (CHS to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to St. Louis

Best Price Found

$154

Fastest flight time

2h 00m

Direct flights

Mon, Tue, Fri, Sat and Sun

Airports in St. Louis

1 airport
The best one-way flight to St. Louis from Charleston in the past 72 hours is $154. The best round-trip flight deal from Charleston to St. Louis found on momondo in the last 72 hours is $332.
The fastest flight from Charleston to St. Louis takes 2h 00m
Direct flights go from Charleston to St. Louis on Monday, Tuesday, Friday, Saturday and Sunday. The only airline offering direct flights is Southwest.
There is 1 airport in St. Louis. From Charleston there are direct flights to Lambert-St Louis (STL).
Search flight deals

Frequently asked questions about flying from Charleston to St. Louis

  • How far is Charleston to Lambert-St Louis by plane?

    A flight from Charleston to Lambert-St Louis will travel around 702.5 mi. A reasonable flight in good conditions will take 2h 00m.

  • When did momondo last update prices for flights from Charleston Airport to Lambert-St Louis Airport?

    Prices for flights from Charleston Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Charleston Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Charleston to St. Louis?

  • What is the most popular airline from Charleston to St. Louis?

Best airlines flying from Charleston to St. Louis

Compare and see reviews for airlines that fly from Charleston to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $206Free CancellationRating
7.8
8,497 reviews
Search Delta flights
SouthwestPriceFrom $228Free CancellationRating
8.0
4,216 reviews
Search Southwest flights
American AirlinesPriceFrom $274Free CancellationRating
7.1
11,893 reviews
Search American Airlines flights

  • Southwest Flights From Charleston to St. Louis

    Southwest flight deals from Charleston to St. Louis start from $228 round-trip. Over the 4 Southwest flights for this route in a normal week, average airfare is usually $393 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Fairview Heights
Hermann
St. Peters
Maryland Heights
Florissant
Collinsville
Alton
O'Fallon
Clayton
Farmington
Fenton
Wentzville
Festus
Eureka
Edwardsville
Litchfield
Grafton
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to St. Louis with flexible booking policies on momondo?

All flight searches from Charleston to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Charleston to St. Louis?

Once you have performed a search for Charleston to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to St. Louis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to St. Louis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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