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Cheap flights from Charleston to St. Louis from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to St. Louis departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Charleston to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
2:15 pm - 3:30 pm
CHS
-
STL
2h 15mnonstop
Southwest Logo
2:10 pm - 5:05 pm
STL
-
CHS
1h 55mnonstop
$239Southwest
Thu, Apr 9 - Mon, Apr 13
Southwest Logo
7:55 pm - 11:15 pm
CHS
-
STL
4h 20m
1 stop
Southwest Logo
2:10 pm - 5:05 pm
STL
-
CHS
1h 55mnonstop
$249Southwest
Thu, Apr 9 - Mon, Apr 13
Southwest Logo
2:15 pm - 3:30 pm
CHS
-
STL
2h 15mnonstop
Southwest Logo
1:45 pm - 8:50 pm
STL
-
CHS
6h 05m
2 stops
$254Southwest
Thu, Apr 9 - Mon, Apr 13
Southwest Logo
4:45 pm - 11:25 pm
CHS
-
STL
7h 40m
1 stop
Southwest Logo
1:45 pm - 9:55 pm
STL
-
CHS
7h 10m
1 stop
$259Southwest
Thu, May 14 - Mon, May 18
Southwest Logo
5:45 pm - 10:40 pm
CHS
-
STL
5h 55m
1 stop
Southwest Logo
1:45 pm - 8:50 pm
STL
-
CHS
6h 05m
2 stops
$264Southwest
Thu, Apr 9 - Mon, Apr 13
Southwest Logo
1:25 pm - 7:05 pm
CHS
-
STL
6h 40m
1 stop
Southwest Logo
3:15 pm - 6:15 pm
STL
-
CHS
2h 00mnonstop
$277Southwest
Fri, Jun 5 - Tue, Jun 9
Southwest Logo
3:15 pm - 12:40 am
CHS
-
STL
10h 25m
2 stops
Southwest Logo
3:15 pm - 6:15 pm
STL
-
CHS
2h 00mnonstop
$282Southwest
Fri, Jun 5 - Tue, Jun 9
American Airlines Logo
12:13 pm - 4:41 pm
CHS
-
STL
5h 28m
1 stop
American Airlines Logo
5:21 pm - 11:08 pm
STL
-
CHS
4h 47m
1 stop
$287American Airlines
Wed, Apr 22 - Sun, Apr 26
Southwest Logo
2:15 pm - 3:30 pm
CHS
-
STL
2h 15mnonstop
Southwest Logo
8:20 am - 3:00 pm
STL
-
CHS
5h 40m
1 stop
$288Southwest
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
8:28 pm - 6:50 am
CHS
-
STL
35h 22m
2 stops
Multiple Airlines Logo
4:59 pm - 8:43 am
STL
-
CHS
14h 44m
1 stop
$289Multiple Airlines
Mon, Apr 20 - Sun, Apr 26

Southwest flights from Charleston to St. Louis

Our best Southwest deals on Charleston to St. Louis flight tickets
Southwest
Apr 9
CHS2:15 pmCharleston
2h 15m
STL3:30 pmLambert-St Louis
Apr 13
STL2:10 pmLambert-St Louis
1h 55m
CHS5:05 pmCharleston
$239
Southwest
Apr 9
CHS7:55 pmCharleston
4h 20m
1 stop
STL11:15 pmLambert-St Louis
Apr 13
STL2:10 pmLambert-St Louis
1h 55m
CHS5:05 pmCharleston
$249
Southwest
Apr 9
CHS2:15 pmCharleston
2h 15m
STL3:30 pmLambert-St Louis
Apr 13
STL1:45 pmLambert-St Louis
6h 05m
2 stops
CHS8:50 pmCharleston
$254

American Airlines flights from Charleston to St. Louis

Our best American Airlines deals on Charleston to St. Louis flight tickets
American Airlines
Apr 22
CHS12:13 pmCharleston
5h 28m
1 stop
STL4:41 pmLambert-St Louis
Apr 26
STL5:21 pmLambert-St Louis
4h 47m
1 stop
CHS11:08 pmCharleston
$287
American Airlines
Apr 22
CHS7:35 amCharleston
6h 13m
1 stop
STL12:48 pmLambert-St Louis
Apr 26
STL6:29 amLambert-St Louis
8h 14m
1 stop
CHS3:43 pmCharleston
$298
American Airlines
Apr 22
CHS7:35 amCharleston
6h 13m
1 stop
STL12:48 pmLambert-St Louis
Apr 26
STL5:51 amLambert-St Louis
4h 58m
1 stop
CHS11:49 amCharleston
$325

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 4/9

2:15 pm-3:30 pm

Nonstop2h 15m

Lambert-St Louis

Mon 4/13

2:10 pm-5:05 pm

Nonstop1h 55m

$239

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 4/9

7:55 pm-11:15 pm

1 stop4h 20m

Lambert-St Louis

Mon 4/13

2:10 pm-5:05 pm

Nonstop1h 55m

$249

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 4/9

2:15 pm-3:30 pm

Nonstop2h 15m

Lambert-St Louis

Mon 4/13

1:45 pm-8:50 pm

2 stops6h 05m

$254

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 5/14

4:45 pm-11:25 pm

1 stop7h 40m

Lambert-St Louis

Mon 5/18

1:45 pm-9:55 pm

1 stop7h 10m

$259

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 4/9

5:45 pm-10:40 pm

1 stop5h 55m

Lambert-St Louis

Mon 4/13

1:45 pm-8:50 pm

2 stops6h 05m

$264

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 6/5

1:25 pm-7:05 pm

1 stop6h 40m

Lambert-St Louis

Tue 6/9

3:15 pm-6:15 pm

Nonstop2h 00m

$277

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 6/5

3:15 pm-12:40 am

2 stops10h 25m

Lambert-St Louis

Tue 6/9

3:15 pm-6:15 pm

Nonstop2h 00m

$282

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Wed 4/22

12:13 pm-4:41 pm

1 stop5h 28m

Lambert-St Louis

Sun 4/26

5:21 pm-11:08 pm

1 stop4h 47m

$287

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 4/23

2:15 pm-3:30 pm

Nonstop2h 15m

Lambert-St Louis

Sun 4/26

8:20 am-3:00 pm

1 stop5h 40m

$288

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Mon 4/20

8:28 pm-6:50 am

2 stops35h 22m

Lambert-St Louis

Sun 4/26

4:59 pm-8:43 am

1 stop14h 44m

$289

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Charleston to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to St. Louis?

In general, February is the cheapest month to fly from Charleston to St. Louis. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $276. The month of September is another great option to travel to St. Louis, with average flight prices from Charleston averaging around $299.

What is the cheapest day to depart on your flight to St. Louis?

The cheapest day to depart on your flight to St. Louis is on a Thursday when prices can be found for as low as $336. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $606. These prices are subject to change though, so be sure to set up a Price Alert for flights to St. Louis.

What is the cheapest time of day to depart on your flight to St. Louis?

Flying to St. Louis from Charleston in the morning is the least expensive time of day to depart. momondo users have found prices as low as $373 when looking at flights departing in the morning. At noon is when there is more demand to fly to St. Louis, so prices are often more expensive at around $464 per ticket.

What is the cheapest Charleston to Lambert-St Louis flight route?

Fly from Charleston to Lambert-St Louis for the best Charleston - Lambert-St Louis flight prices

What cabin class options are available on Charleston to Lambert-St Louis flights?

There is only 1 cabin class available to choose from on Charleston to Lambert-St Louis flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Charleston to St. Louis flights?

You could potentially save up to 31% on your flight if you consider stops on a Charleston to St. Louis flight.

How have Charleston to St. Louis flight prices changed over time?

As of March 2026, prices for Charleston to St. Louis flights are approximately 21% more expensive when compared to flights at the same time last year.

When to book flights from Charleston to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to St. Louis (CHS to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to St. Louis

Best Price Found

$412

Fastest flight time

2h 05m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in St. Louis

1 airport
The best flight deal from Charleston to St. Louis found on momondo in the last 72 hours is $412
The fastest flight from Charleston to St. Louis takes 2h 05m
Direct flights go from Charleston to St. Louis on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in St. Louis. From Charleston there are direct flights to Lambert-St Louis (STL).
Search flight deals

  • How far is Charleston to Lambert-St Louis by plane?

    A flight from Charleston to Lambert-St Louis will travel around 702.5 mi. A reasonable flight in good conditions will take 2h 05m.

  • When did momondo last update prices for flights from Charleston Airport to Lambert-St Louis Airport?

    Prices for flights from Charleston Airport to Lambert-St Louis Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Charleston Airport to Lambert-St Louis Airport?

  • How old do you have to be to fly from Charleston Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The required travel and health documents for your Lambert-St Louis Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Lambert-St Louis Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Charleston to St. Louis?

  • What is the most popular airline from Charleston to St. Louis?

Best airlines flying from Charleston to St. Louis

Compare and see reviews for airlines that fly from Charleston to St. Louis with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $246Free CancellationRating
7.9
8,288 reviews
Search Delta flights
American AirlinesPriceFrom $274Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights
SouthwestPriceFrom $287Free CancellationRating
8.0
4,320 reviews
Search Southwest flights

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Florissant
Maryland Heights
O'Fallon
Collinsville
Alton
St. Peters
Wentzville
Fenton
Farmington
Clayton
Edwardsville
Festus
Eureka
Litchfield
Shrewsbury
Grafton

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to St. Louis with flexible booking policies on momondo?

All flight searches from Charleston to St. Louis on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Charleston to St. Louis?

Once you have performed a search for Charleston to St. Louis flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to St. Louis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Charleston to St. Louis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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