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Cheap flights from Charleston to Panama City from $288

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:20 pm - 11:46 pm
CHS
-
ECP
6h 26m
1 stop
American Airlines Logo
10:48 am - 4:06 pm
ECP
-
CHS
4h 18m
1 stop
$305American Airlines
Thu, May 14 - Mon, May 18
Delta Logo
4:55 pm - 7:09 pm
CHS
-
ECP
3h 14m
1 stop
Delta Logo
9:23 am - 1:45 pm
ECP
-
CHS
3h 22m
1 stop
$335Delta
Thu, Jun 4 - Tue, Jun 9
Delta Logo
5:30 am - 10:14 am
CHS
-
ECP
5h 44m
1 stop
Delta Logo
7:45 am - 1:45 pm
ECP
-
CHS
5h 00m
1 stop
$355Delta
Fri, Jun 12 - Mon, Jun 15
American Airlines Logo
7:50 pm - 11:40 pm
CHS
-
ECP
4h 50m
1 stop
American Airlines Logo
7:05 am - 6:51 pm
ECP
-
CHS
10h 46m
2 stops
$360American Airlines
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
1:15 pm - 8:45 pm
CHS
-
ECP
8h 30m
1 stop
Southwest Logo
7:20 am - 2:45 pm
ECP
-
CHS
6h 25m
1 stop
$361Southwest
Tue, Jun 2 - Sun, Jun 7
Southwest Logo
3:40 pm - 8:25 pm
CHS
-
ECP
5h 45m
1 stop
Southwest Logo
5:40 am - 4:20 pm
ECP
-
CHS
9h 40m
2 stops
$366Southwest
Tue, Jun 2 - Sun, Jun 7
Southwest Logo
12:00 pm - 8:45 pm
CHS
-
ECP
9h 45m
2 stops
Southwest Logo
5:40 am - 4:20 pm
ECP
-
CHS
9h 40m
2 stops
$371Southwest
Tue, Jun 2 - Sun, Jun 7
Delta Logo
7:59 pm - 10:46 pm
CHS
-
ECP
3h 47m
1 stop
Delta Logo
2:47 pm - 9:45 pm
ECP
-
CHS
5h 58m
1 stop
$375Delta
Fri, Jun 12 - Mon, Jun 15
American Airlines Logo
7:50 pm - 11:40 pm
CHS
-
ECP
4h 50m
1 stop
American Airlines Logo
7:05 am - 6:51 pm
ECP
-
CHS
10h 46m
2 stops
$380American Airlines
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
6:25 am - 12:45 pm
CHS
-
ECP
7h 20m
2 stops
Southwest Logo
7:40 am - 8:40 pm
ECP
-
CHS
12h 00m
2 stops
$392Southwest
Thu, Jun 4 - Tue, Jun 9

Delta flights from Charleston to Panama City, Florida

Our best Delta deals on Charleston to Panama City, Florida flight tickets
Delta
Jun 4
CHS4:55 pmCharleston
3h 14m
1 stop
ECP7:09 pmPanama City NW Florida Beaches
Jun 9
ECP9:23 amPanama City NW Florida Beaches
3h 22m
1 stop
CHS1:45 pmCharleston
$335
Delta
Jun 12
CHS5:30 amCharleston
5h 44m
1 stop
ECP10:14 amPanama City NW Florida Beaches
Jun 15
ECP7:45 amPanama City NW Florida Beaches
5h 00m
1 stop
CHS1:45 pmCharleston
$355
Delta
Jun 12
CHS7:59 pmCharleston
3h 47m
1 stop
ECP10:46 pmPanama City NW Florida Beaches
Jun 15
ECP2:47 pmPanama City NW Florida Beaches
5h 58m
1 stop
CHS9:45 pmCharleston
$375

Southwest flights from Charleston to Panama City, Florida

Our best Southwest deals on Charleston to Panama City, Florida flight tickets
Southwest
May 8
CHS2:15 pmCharleston
5h 05m
1 stop
ECP6:20 pmPanama City NW Florida Beaches
May 10
ECP5:35 amPanama City NW Florida Beaches
10h 55m
1 stop
CHS5:30 pmCharleston
$361
Southwest
May 8
CHS1:15 pmCharleston
9h 25m
2 stops
ECP9:40 pmPanama City NW Florida Beaches
May 10
ECP5:35 amPanama City NW Florida Beaches
8h 25m
2 stops
CHS3:00 pmCharleston
$366
Southwest
Jun 2
CHS12:00 pmCharleston
9h 45m
2 stops
ECP8:45 pmPanama City NW Florida Beaches
Jun 7
ECP5:40 amPanama City NW Florida Beaches
9h 40m
2 stops
CHS4:20 pmCharleston
$371

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Charleston to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 5/14

6:20 pm-11:46 pm

1 stop6h 26m

Panama City NW Florida Beaches

Mon 5/18

10:48 am-4:06 pm

1 stop4h 18m

$305

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 6/4

4:55 pm-7:09 pm

1 stop3h 14m

Panama City NW Florida Beaches

Tue 6/9

9:23 am-1:45 pm

1 stop3h 22m

$335

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Fri 6/12

5:30 am-10:14 am

1 stop5h 44m

Panama City NW Florida Beaches

Mon 6/15

7:45 am-1:45 pm

1 stop5h 00m

$355

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 6/4

7:50 pm-11:40 pm

1 stop4h 50m

Panama City NW Florida Beaches

Tue 6/9

7:05 am-6:51 pm

2 stops10h 46m

$360

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Tue 6/2

1:15 pm-8:45 pm

1 stop8h 30m

Panama City NW Florida Beaches

Sun 6/7

7:20 am-2:45 pm

1 stop6h 25m

$361

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Tue 6/2

3:40 pm-8:25 pm

1 stop5h 45m

Panama City NW Florida Beaches

Sun 6/7

5:40 am-4:20 pm

2 stops9h 40m

$366

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Tue 6/2

12:00 pm-8:45 pm

2 stops9h 45m

Panama City NW Florida Beaches

Sun 6/7

5:40 am-4:20 pm

2 stops9h 40m

$371

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Fri 6/12

7:59 pm-10:46 pm

1 stop3h 47m

Panama City NW Florida Beaches

Mon 6/15

2:47 pm-9:45 pm

1 stop5h 58m

$375

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 6/4

7:50 pm-11:40 pm

1 stop4h 50m

Panama City NW Florida Beaches

Tue 6/9

7:05 am-6:51 pm

2 stops10h 46m

$380

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 6/4

6:25 am-12:45 pm

2 stops7h 20m

Panama City NW Florida Beaches

Tue 6/9

7:40 am-8:40 pm

2 stops12h 00m

$392

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from Charleston is in March. Flight prices, which tend to average around $298, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Panama City, Florida, with average flight prices from Charleston averaging around $304.

When to book flights from Charleston to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City, Florida (CHS to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City, Florida

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from Charleston to Panama City, Florida takes 4h 06m
There are no direct flights from Charleston to Panama City, Florida. There are no popular flight routes from Charleston to Panama City, Florida.
Search flight deals

  • How far is Charleston to Panama City NW Florida Beaches by plane?

    Panama City NW Florida Beaches is 382.6 mi away from Charleston. Typically, this will take 4h 06m by plane in normal conditions.

  • When did momondo last update prices for flights from Charleston Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Charleston Airport to Panama City NW Florida Beaches Airport were last updated today.

  • How many operators does momondo search for flights from Charleston Airport to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City NW Florida Beaches Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Charleston Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Charleston to Panama City, Florida?

Best airlines flying from Charleston to Panama City, Florida

Compare and see reviews for airlines that fly from Charleston to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $231Free CancellationRating
7.9
8,245 reviews
Search Delta flights
American AirlinesPriceFrom $272Free CancellationRating
7.1
11,378 reviews
Search American Airlines flights
SouthwestPriceFrom $283Free CancellationRating
8.0
4,304 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

Finding the right flight to Panama City from Charleston is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Charleston with this policy.

How can momondo help me find flights from Charleston to Panama City?

momondo helps you find the best flight between Charleston and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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