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Cheap flights from Central America to Greenville from $280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Central America to Greenville departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Central America to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
9:00 am - 10:15 pm
SJO
-
GSP
11h 15m
2 stops
Southwest Logo
6:45 am - 7:00 pm
GSP
-
SJO
14h 15m
2 stops
$458Southwest
Thu, May 14 - Wed, May 20
Southwest Logo
9:00 am - 9:40 pm
SJO
-
GSP
10h 40m
2 stops
Southwest Logo
6:45 am - 7:00 pm
GSP
-
SJO
14h 15m
2 stops
$485Southwest
Tue, May 19 - Tue, May 26
American Airlines Logo
3:10 pm - 12:21 am
PTY
-
GSP
8h 11m
1 stop
American Airlines Logo
6:22 pm - 3:01 pm
GSP
-
PTY
21h 39m
2 stops
$492American Airlines
Thu, Mar 19 - Mon, Mar 30
American Airlines Logo
3:10 pm - 12:21 am
PTY
-
GSP
8h 11m
1 stop
American Airlines Logo
7:26 pm - 3:01 pm
GSP
-
PTY
20h 35m
1 stop
$497American Airlines
Thu, Mar 19 - Mon, Mar 30
Delta Logo
2:13 pm - 11:54 pm
SAL
-
GSP
7h 41m
1 stop
Delta Logo
5:40 am - 12:48 pm
GSP
-
SAL
9h 08m
1 stop
$504Delta
Tue, Mar 31 - Tue, Apr 7
Southwest Logo
9:00 am - 9:40 pm
SJO
-
GSP
10h 40m
2 stops
Southwest Logo
6:45 am - 7:00 pm
GSP
-
SJO
14h 15m
2 stops
$506Southwest
Tue, May 19 - Tue, May 26
Copa Airlines Logo
6:19 pm - 9:55 am
SJO
-
GSP
13h 36m
2 stops
Copa Airlines Logo
10:33 am - 7:08 am
GSP
-
SJO
22h 35m
2 stops
$547Copa Airlines
Tue, Apr 7 - Tue, Apr 14
Delta Logo
1:20 pm - 11:54 pm
SJO
-
GSP
8h 34m
1 stop
Delta Logo
8:30 am - 9:15 pm
GSP
-
SJO
14h 45m
1 stop
$567Delta
Wed, Mar 25 - Wed, Apr 1
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
GSP
13h 04m
1 stop
United Airlines Logo
11:18 am - 7:31 pm
GSP
-
PTY
9h 13m
1 stop
$577United Airlines
Thu, May 28 - Mon, Jun 1
United Airlines Logo
3:41 pm - 9:59 pm
PTY
-
GSP
29h 18m
1 stop
United Airlines Logo
4:41 pm - 2:14 pm
GSP
-
PTY
22h 33m
1 stop
$1,035United Airlines
Sat, Mar 28 - Sat, Apr 4

American Airlines flights from Central America to Greenville

Our best American Airlines deals on Central America to Greenville flight tickets
American Airlines
Mar 19
PTY3:10 pmPanama City Tocumen Intl
8h 11m
1 stop
GSP12:21 amGreenville
Mar 30
GSP6:22 pmGreenville
21h 39m
2 stops
PTY3:01 pmPanama City Tocumen Intl
$492
American Airlines
Mar 19
PTY3:10 pmPanama City Tocumen Intl
8h 11m
1 stop
GSP12:21 amGreenville
Mar 30
GSP7:26 pmGreenville
20h 35m
1 stop
PTY3:01 pmPanama City Tocumen Intl
$497
American Airlines
Apr 16
PTY1:49 pmPanama City Tocumen Intl
9h 10m
1 stop
GSP11:59 pmGreenville
May 15
GSP6:45 pmGreenville
19h 01m
1 stop
PTY12:46 pmPanama City Tocumen Intl
$507

Southwest flights from Central America to Greenville

Our best Southwest deals on Central America to Greenville flight tickets
Southwest
May 14
SJO9:00 amSan José Juan Santamaria Intl
11h 15m
2 stops
GSP10:15 pmGreenville
May 20
GSP6:45 amGreenville
14h 15m
2 stops
SJO7:00 pmSan José Juan Santamaria Intl
$458
Southwest
May 19
SJO9:00 amSan José Juan Santamaria Intl
10h 40m
2 stops
GSP9:40 pmGreenville
May 26
GSP6:45 amGreenville
14h 15m
2 stops
SJO7:00 pmSan José Juan Santamaria Intl
$485
Southwest
May 19
SJO9:00 amSan José Juan Santamaria Intl
10h 40m
2 stops
GSP9:40 pmGreenville
May 26
GSP6:45 amGreenville
14h 15m
2 stops
SJO7:00 pmSan José Juan Santamaria Intl
$506

momondo Fare Finder

 
Customize your flight search to find flights from Central America to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Central America to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San JoséGreenville

SJO - GSP

SJOGSP

San José Juan Santamaria Intl

Thu 5/14

9:00 am-10:15 pm

2 stops11h 15m

Greenville

Wed 5/20

6:45 am-7:00 pm

2 stops14h 15m

$458

San JoséGreenville

SJO - GSP

SJOGSP

San José Juan Santamaria Intl

Tue 5/19

9:00 am-9:40 pm

2 stops10h 40m

Greenville

Tue 5/26

6:45 am-7:00 pm

2 stops14h 15m

$485

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 3/19

3:10 pm-12:21 am

1 stop8h 11m

Greenville

Mon 3/30

6:22 pm-3:01 pm

2 stops21h 39m

$492

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 3/19

3:10 pm-12:21 am

1 stop8h 11m

Greenville

Mon 3/30

7:26 pm-3:01 pm

1 stop20h 35m

$497

San SalvadorGreenville

SAL - GSP

SALGSP

San Salvador El Salvador Intl

Tue 3/31

2:13 pm-11:54 pm

1 stop7h 41m

Greenville

Tue 4/7

5:40 am-12:48 pm

1 stop9h 08m

$504

San JoséGreenville

SJO - GSP

SJOGSP

San José Juan Santamaria Intl

Tue 5/19

9:00 am-9:40 pm

2 stops10h 40m

Greenville

Tue 5/26

6:45 am-7:00 pm

2 stops14h 15m

$506

San JoséGreenville

SJO - GSP

SJOGSP

San José Juan Santamaria Intl

Tue 4/7

6:19 pm-9:55 am

2 stops13h 36m

Greenville

Tue 4/14

10:33 am-7:08 am

2 stops22h 35m

$547

San JoséGreenville

SJO - GSP

SJOGSP

San José Juan Santamaria Intl

Wed 3/25

1:20 pm-11:54 pm

1 stop8h 34m

Greenville

Wed 4/1

8:30 am-9:15 pm

1 stop14h 45m

$567

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 5/28

7:55 am-9:59 pm

1 stop13h 04m

Greenville

Mon 6/1

11:18 am-7:31 pm

1 stop9h 13m

$577

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Sat 3/28

3:41 pm-9:59 pm

1 stop29h 18m

Greenville

Sat 4/4

4:41 pm-2:14 pm

1 stop22h 33m

$1,035

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Central America to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Central America to Greenville flights?

You could potentially save up to 19% on your flight if you consider stops on a Central America to Greenville flight.

Cheap Central America to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Central America to Greenville

Fastest flight time

7h 30m

Direct flights

None
The fastest flight from Central America to Greenville takes 7h 30m
There are no direct flights from Central America to Greenville. There are no popular flight routes from Central America to Greenville.
Search flight deals

  • When did momondo last update prices for flights from Central America to Greenville Airport?

    Prices for flights from Central America to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Central America to Greenville Airport?

  • How old do you have to be to fly from Central America to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Central America to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Central America to Greenville

Compare and see reviews for airlines that fly from Central America to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $298Free CancellationRating
7.9
8,237 reviews
Search Delta flights
United AirlinesPriceFrom $310Free CancellationRating
7.4
9,375 reviews
Search United Airlines flights
American AirlinesPriceFrom $413Free CancellationRating
7.1
11,369 reviews
Search American Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Central America to Greenville?

Finding the right flight to Greenville from Central America is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Central America to Greenville with flexible booking policies on momondo?

Yes. All flights to Greenville from Central America on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Central America to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Central America to Greenville.

I’m not ready to book a flight from Central America to Greenville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Central America to Greenville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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