What airlines fly to South Carolina?

Breeze Airways, American Airlines and Delta are the top three most popular airlines that fly to South Carolina from Buffalo according to our data. Breeze Airways is the first choice among our users, with 39% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 8 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

How many flights depart from Buffalo to South Carolina on average per week?

As of April 2026, 19 flights take off from Buffalo and land in South Carolina each week. The most common flight departure day for this route is Mon, with 16% of weekly flights taking off on this day.

What is the cheapest airline that flies from Buffalo to South Carolina?

Frontier, United Airlines, and Delta are the most popular carriers operating from Buffalo to South Carolina

When did momondo last update prices for flights from Buffalo Airport to South Carolina?

Prices for flights from Buffalo Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Buffalo Airport to South Carolina?

As of April 2026, there are 6 operators available to choose from for flights from Buffalo Airport to South Carolina.

How old do you have to be to fly from Buffalo Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$77 Cheap Flights from Buffalo to South Carolina in 2026

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Find the cheapest flights from Buffalo to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:52 pm - 9:38 am

BUF

CHS

13h 46m

1 stop

2:39 pm - 10:41 am

CHS

BUF

44h 02m

2 stops

$210Multiple Airlines

Tue, May 26 - Tue, Jun 2

2:49 pm - 8:36 pm

BUF

MYR

29h 47m

2 stops

3:53 pm - 6:59 pm

MYR

BUF

27h 06m

1 stop

$224Multiple Airlines

Fri, May 29 - Thu, Jun 4

7:28 pm - 11:53 pm

BUF

SAV

4h 25m

1 stop

6:57 pm - 11:49 pm

SAV

BUF

4h 52m

1 stop

$251American Airlines

Mon, May 11 - Sat, May 16

10:44 am - 5:41 pm

BUF

SAV

6h 57m

2 stops

6:30 am - 1:05 pm

SAV

BUF

6h 35m

1 stop

$256American Airlines

Wed, May 6 - Sat, May 9

12:14 pm - 5:18 pm

BUF

CHS

5h 04m

1 stop

6:24 pm - 10:57 pm

CHS

BUF

4h 33m

1 stop

$256Delta

Mon, Jun 8 - Sat, Jun 13

6:00 am - 11:54 am

BUF

CHS

5h 54m

1 stop

6:00 am - 10:35 am

CHS

BUF

4h 35m

1 stop

$257Delta

Sat, Aug 8 - Sat, Aug 15

6:00 am - 1:55 pm

BUF

CHS

7h 55m

2 stops

10:00 am - 2:22 pm

CHS

BUF

4h 22m

1 stop

$269United Airlines

Tue, Sep 15 - Tue, Sep 22

6:10 am - 10:13 am

BUF

CHS

4h 03m

1 stop

11:31 am - 4:46 pm

CHS

BUF

5h 15m

1 stop

$271United Airlines

Mon, May 18 - Thu, May 21

4:00 pm - 8:55 pm

BUF

GSP

4h 55m

1 stop

12:50 pm - 10:15 pm

GSP

BUF

9h 25m

2 stops

$286Southwest

Mon, Jun 1 - Tue, Jun 2

1:10 pm - 8:00 pm

BUF

GSP

6h 50m

1 stop

1:50 pm - 9:25 pm

GSP

BUF

7h 35m

2 stops

$316Southwest

Wed, Jun 3 - Tue, Jun 9

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Frontier flights from Buffalo to South Carolina

Our best Frontier deals on Buffalo to South Carolina flight tickets

Frontier

Jun 2

BUF7:52 pmBuffalo

16h 13m

1 stop

CLT12:05 pmCharlotte Douglas

Jun 4

CLT6:41 pmCharlotte Douglas

19h 13m

2 stops

BUF1:54 pmBuffalo

$278

Frontier

May 8

BUF7:41 pmBuffalo

16h 24m

1 stop

CLT12:05 pmCharlotte Douglas

May 11

CLT5:28 pmCharlotte Douglas

17h 13m

2 stops

BUF10:41 amBuffalo

$280

Frontier

Apr 23

BUF11:19 amBuffalo

22h 53m

1 stop

CLT10:12 amCharlotte Douglas

Apr 26

CLT7:19 pmCharlotte Douglas

24h 07m

1 stop

BUF7:26 pmBuffalo

$281

American Airlines flights from Buffalo to South Carolina

Our best American Airlines deals on Buffalo to South Carolina flight tickets

American Airlines

May 11

BUF7:28 pmBuffalo

4h 25m

1 stop

SAV11:53 pmSavannah/Hilton Head

May 16

SAV6:57 pmSavannah/Hilton Head

4h 52m

1 stop

BUF11:49 pmBuffalo

$251

American Airlines

May 6

BUF10:44 amBuffalo

6h 57m

2 stops

SAV5:41 pmSavannah/Hilton Head

May 9

SAV6:30 amSavannah/Hilton Head

6h 35m

1 stop

BUF1:05 pmBuffalo

$256

American Airlines

May 1

BUF7:28 pmBuffalo

4h 30m

1 stop

SAV11:58 pmSavannah/Hilton Head

May 9

SAV6:57 pmSavannah/Hilton Head

4h 52m

1 stop

BUF11:49 pmBuffalo

$267

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Tue 5/26

7:52 pm-9:38 am

1 stop13h 46m

Charleston

Tue 6/2

2:39 pm-10:41 am

2 stops44h 02m

$210

BuffaloMyrtle Beach

BUF - MYR

BUFMYR

Buffalo

Fri 5/29

2:49 pm-8:36 pm

2 stops29h 47m

Myrtle Beach Intl

Thu 6/4

3:53 pm-6:59 pm

1 stop27h 06m

$224

Quickest round-trip

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Mon 5/11

7:28 pm-11:53 pm

1 stop4h 25m

Savannah/Hilton Head

Sat 5/16

6:57 pm-11:49 pm

1 stop4h 52m

$251

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Wed 5/6

10:44 am-5:41 pm

2 stops6h 57m

Savannah/Hilton Head

Sat 5/9

6:30 am-1:05 pm

1 stop6h 35m

$256

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Mon 6/8

12:14 pm-5:18 pm

1 stop5h 04m

Charleston

Sat 6/13

6:24 pm-10:57 pm

1 stop4h 33m

$256

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sat 8/8

6:00 am-11:54 am

1 stop5h 54m

Charleston

Sat 8/15

6:00 am-10:35 am

1 stop4h 35m

$257

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Tue 9/15

6:00 am-1:55 pm

2 stops7h 55m

Charleston

Tue 9/22

10:00 am-2:22 pm

1 stop4h 22m

$269

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Mon 5/18

6:10 am-10:13 am

1 stop4h 03m

Charleston

Thu 5/21

11:31 am-4:46 pm

1 stop5h 15m

$271

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Mon 6/1

4:00 pm-8:55 pm

1 stop4h 55m

Greenville

Tue 6/2

12:50 pm-10:15 pm

2 stops9h 25m

$286

BuffaloGreenville

BUF - GSP

BUFGSP

Buffalo

Wed 6/3

1:10 pm-8:00 pm

1 stop6h 50m

Greenville

Tue 6/9

1:50 pm-9:25 pm

2 stops7h 35m

$316

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Buffalo is in February. Flight prices, which tend to average around $201, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to South Carolina from Buffalo during September instead. Flights to South Carolina in September, while not as cheap as those in February, still average around $236.

How far in advance should I book a flight to South Carolina?

You are more likely to see cheaper flights to South Carolina from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $284 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Buffalo for as low as $217 on momondo.

Cheap Buffalo to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to South Carolina

Fastest flight time	1h 55m
Direct flights	Every day
Airports in South Carolina	57 airports

The fastest flight from Buffalo to South Carolina takes 1h 55m

Direct flights go from Buffalo to South Carolina every day.

There are 57 airports in South Carolina. From Buffalo there are direct flights to Charlotte Douglas (CLT).

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Frequently asked questions about flying from Buffalo to South Carolina

When did momondo last update prices for flights from Buffalo Airport to South Carolina?
Prices for flights from Buffalo Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Buffalo Airport to South Carolina?
As of April 2026, there are 6 operators available to choose from for flights from Buffalo Airport to South Carolina.
How old do you have to be to fly from Buffalo Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Buffalo Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Buffalo to South Carolina

Compare and see reviews for airlines that fly from Buffalo to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $80	Free Cancellation	Rating 7.2 2,945 reviews	Search JetBlue flights
Delta	PriceFrom $108	Free Cancellation	Rating 7.9 8,424 reviews	Search Delta flights
American Airlines	PriceFrom $198	Free Cancellation	Rating 7.1 11,605 reviews	Search American Airlines flights
United Airlines	PriceFrom $200	Free Cancellation	Rating 7.4 9,603 reviews	Search United Airlines flights
Southwest	PriceFrom $236	Free Cancellation	Rating 8.0 4,330 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to South Carolina?

It is quick and easy to find Buffalo to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Buffalo to South Carolina with flexible booking policies on momondo?

All flight searches from Buffalo to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Buffalo to South Carolina?

Once all potential Buffalo to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Buffalo to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Buffalo and alert you when they change.