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Cheap flights from Buffalo to Des Moines from $209

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:15 am - 9:42 amBUF  Buffalo-DSM Des Moines
4h 27m1 stop Detroit Metropolitan Wayne County
Delta Logo
5:50 pm - 11:59 pmDSM  Des Moines-BUF Buffalo
5h 09m1 stop Detroit Metropolitan Wayne County
$325Delta
Wed, Oct 7 - Mon, Oct 12
Southwest Logo
7:35 pm - 11:10 pmBUF  Buffalo-DSM Des Moines
4h 35m1 stop Chicago Midway
Southwest Logo
5:10 am - 10:25 amDSM  Des Moines-BUF Buffalo
4h 15m1 stop Chicago Midway
$345Southwest
Thu, Oct 1 - Mon, Oct 5
Southwest Logo
7:35 pm - 11:15 pmBUF  Buffalo-DSM Des Moines
4h 40m1 stop Chicago Midway
Southwest Logo
1:20 pm - 6:55 pmDSM  Des Moines-BUF Buffalo
4h 35m1 stop Chicago Midway
$358Southwest
Fri, Oct 16 - Sat, Oct 17
Southwest Logo
7:35 pm - 11:15 pmBUF  Buffalo-DSM Des Moines
4h 40m1 stop Chicago Midway
Southwest Logo
5:50 am - 5:35 pmDSM  Des Moines-BUF Buffalo
10h 45m2 stops Chicago Midway Baltimore/Washington
$363Southwest
Fri, Oct 16 - Sat, Oct 17
Southwest Logo
7:35 pm - 11:10 pmBUF  Buffalo-DSM Des Moines
4h 35m1 stop Chicago Midway
Southwest Logo
5:10 am - 2:10 pmDSM  Des Moines-BUF Buffalo
8h 00m2 stops Chicago Midway Baltimore/Washington
$370Southwest
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
1:48 pm - 5:48 pmBUF  Buffalo-DSM Des Moines
5h 00m1 stop Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 8:47 pmDSM  Des Moines-BUF Buffalo
4h 36m1 stop Chicago O'Hare Intl
$371United Airlines
Wed, Oct 7 - Sun, Oct 11
American Airlines Logo
7:55 am - 1:28 pmBUF  Buffalo-DSM Des Moines
6h 33m1 stop Chicago O'Hare Intl
American Airlines Logo
1:58 pm - 9:37 pmDSM  Des Moines-BUF Buffalo
6h 39m1 stop Chicago O'Hare Intl
$371American Airlines
Sun, Nov 1 - Sat, Nov 7
American Airlines Logo
5:57 pm - 12:14 amBUF  Buffalo-DSM Des Moines
7h 17m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl
American Airlines Logo
6:05 am - 12:46 pmDSM  Des Moines-BUF Buffalo
5h 41m1 stop Philadelphia
$376American Airlines
Wed, Oct 7 - Sun, Oct 11
Southwest Logo
9:15 am - 6:35 pmBUF  Buffalo-DSM Des Moines
10h 20m1 stop Phoenix Sky Harbor Intl
Southwest Logo
12:45 pm - 9:35 pmDSM  Des Moines-BUF Buffalo
7h 50m2 stops Chicago Midway Baltimore/Washington
$376Southwest
Sun, Nov 1 - Sat, Nov 7
United Airlines Logo
7:00 am - 10:31 amBUF  Buffalo-DSM Des Moines
4h 31m1 stop Chicago O'Hare Intl
United Airlines Logo
1:24 pm - 8:47 pmDSM  Des Moines-BUF Buffalo
6h 23m1 stop Chicago O'Hare Intl
$405United Airlines
Tue, Oct 20 - Wed, Oct 21

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Delta flights from Buffalo to Des Moines

Our best Delta deals on Buffalo to Des Moines flight tickets
Delta
Oct 7
BUF6:15 amBuffalo
4h 27m
1 stop
DSM9:42 amDes Moines
Oct 12
DSM5:50 pmDes Moines
5h 09m
1 stop
BUF11:59 pmBuffalo
$325
Delta
Oct 9
BUF6:15 amBuffalo
9h 10m
2 stops
DSM2:25 pmDes Moines
Oct 12
DSM3:46 pmDes Moines
7h 13m
2 stops
BUF11:59 pmBuffalo
$1,724

Southwest flights from Buffalo to Des Moines

Our best Southwest deals on Buffalo to Des Moines flight tickets
Southwest
Oct 1
BUF7:35 pmBuffalo
4h 35m
1 stop
DSM11:10 pmDes Moines
Oct 5
DSM5:10 amDes Moines
4h 15m
1 stop
BUF10:25 amBuffalo
$345
Southwest
Oct 16
BUF7:35 pmBuffalo
4h 40m
1 stop
DSM11:15 pmDes Moines
Oct 17
DSM1:20 pmDes Moines
4h 35m
1 stop
BUF6:55 pmBuffalo
$358
Southwest
Oct 16
BUF7:35 pmBuffalo
4h 40m
1 stop
DSM11:15 pmDes Moines
Oct 17
DSM5:50 amDes Moines
10h 45m
2 stops
BUF5:35 pmBuffalo
$363

momondo Fare Finder

 
Use the filters below to find and compare flights from Buffalo to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Wed 10/7

6:15 am-9:42 am

1 stop4h 27m

Des Moines

Mon 10/12

5:50 pm-11:59 pm

1 stop5h 09m

$325
Quickest round-trip

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Thu 10/1

7:35 pm-11:10 pm

1 stop4h 35m

Des Moines

Mon 10/5

5:10 am-10:25 am

1 stop4h 15m

$345

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Fri 10/16

7:35 pm-11:15 pm

1 stop4h 40m

Des Moines

Sat 10/17

1:20 pm-6:55 pm

1 stop4h 35m

$358

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Fri 10/16

7:35 pm-11:15 pm

1 stop4h 40m

Des Moines

Sat 10/17

5:50 am-5:35 pm

2 stops10h 45m

$363

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Thu 10/1

7:35 pm-11:10 pm

1 stop4h 35m

Des Moines

Mon 10/5

5:10 am-2:10 pm

2 stops8h 00m

$370

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Wed 10/7

1:48 pm-5:48 pm

1 stop5h 00m

Des Moines

Sun 10/11

3:11 pm-8:47 pm

1 stop4h 36m

$371

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Sun 11/1

7:55 am-1:28 pm

1 stop6h 33m

Des Moines

Sat 11/7

1:58 pm-9:37 pm

1 stop6h 39m

$371

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Wed 10/7

5:57 pm-12:14 am

2 stops7h 17m

Des Moines

Sun 10/11

6:05 am-12:46 pm

1 stop5h 41m

$376

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Sun 11/1

9:15 am-6:35 pm

1 stop10h 20m

Des Moines

Sat 11/7

12:45 pm-9:35 pm

2 stops7h 50m

$376

BuffaloDes Moines

BUF Buffalo - DSM Des Moines

BUFDSM

Buffalo

Tue 10/20

7:00 am-10:31 am

1 stop4h 31m

Des Moines

Wed 10/21

1:24 pm-8:47 pm

1 stop6h 23m

$405

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Buffalo to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in January, then April is your next best option. Flight prices from Buffalo to Des Moines during April average around $364.

Can stopping save me money on Buffalo to Des Moines flights?

You could potentially save up to 50% on your flight if you consider stops on a Buffalo to Des Moines flight.

When to book flights from Buffalo to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Des Moines (BUF to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Des Moines

Best Price Found

$209

Fastest flight time

4h 20m

Direct flights

None
The best one-way flight to Des Moines from Buffalo in the past 72 hours is $209. The best round-trip flight deal from Buffalo to Des Moines found on momondo in the last 72 hours is $325.
The fastest flight from Buffalo to Des Moines takes 4h 20m
There are no direct flights from Buffalo to Des Moines. There are no popular flight routes from Buffalo to Des Moines.
Search flight deals

Frequently asked questions about flying from Buffalo to Des Moines

  • How far is Buffalo to Des Moines by plane?

    Buffalo and Des Moines are 758.3 mi apart from one another. Flights usually cover this in 4h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Buffalo Airport to Des Moines Airport?

    Prices for flights from Buffalo Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Buffalo Airport to Des Moines Airport?

  • How old do you have to be to fly from Buffalo Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Buffalo Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Buffalo to Des Moines?

Best airlines flying from Buffalo to Des Moines

Compare and see reviews for airlines that fly from Buffalo to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $335Free CancellationRating
7.4
10,158 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Newton
Osceola
Boone
Johnston
Oskaloosa
Norwalk
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Des Moines?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Buffalo to Des Moines for you.

Can I find flights from Buffalo to Des Moines with flexible booking policies on momondo?

Flights from Buffalo to Des Moines with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to Des Moines?

momondo helps you find the best flight between Buffalo and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to Des Moines right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Buffalo to Des Moines now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Des Moines and let you know when they change.

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