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Cheap flights from Boston to Florence from $339

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Boston to Florence departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Boston to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:23 pm - 10:43 pm
BOS
-
FLO
4h 20m1 stop
American Airlines Logo
5:36 pm - 10:22 pm
FLO
-
BOS
4h 46m1 stop
$339American Airlines
Tue, Jan 6 - Sat, Jan 10
American Airlines Logo
4:20 pm - 10:43 pm
BOS
-
FLO
6h 23m2 stops
American Airlines Logo
6:15 am - 10:29 am
FLO
-
BOS
4h 14m1 stop
$344American Airlines
Tue, Jan 6 - Sat, Jan 10
American Airlines Logo
9:52 am - 5:09 pm
BOS
-
FLO
7h 17m2 stops
American Airlines Logo
6:15 am - 5:06 pm
FLO
-
BOS
10h 51m2 stops
$349American Airlines
Tue, Jan 6 - Sat, Jan 10
American Airlines Logo
9:00 am - 2:10 pm
BOS
-
FLO
5h 10m1 stop
American Airlines Logo
2:33 pm - 8:09 pm
FLO
-
BOS
5h 36m1 stop
$419American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
5:17 am - 2:10 pm
BOS
-
FLO
8h 53m2 stops
American Airlines Logo
2:33 pm - 6:26 pm
FLO
-
BOS
3h 53m1 stop
$424American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
5:17 am - 2:10 pm
BOS
-
FLO
8h 53m2 stops
American Airlines Logo
2:33 pm - 9:08 pm
FLO
-
BOS
6h 35m2 stops
$429American Airlines
Sat, Apr 25 - Sat, May 2
American Airlines Logo
7:23 pm - 11:41 pm
BOS
-
FLO
4h 18m1 stop
American Airlines Logo
2:33 pm - 8:09 pm
FLO
-
BOS
5h 36m1 stop
$502American Airlines
Sat, Apr 25 - Sun, May 3
American Airlines Logo
9:00 am - 2:10 pm
BOS
-
FLO
5h 10m1 stop
American Airlines Logo
5:13 am - 10:58 am
FLO
-
BOS
5h 45m1 stop
$506American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
7:23 pm - 11:41 pm
BOS
-
FLO
4h 18m1 stop
American Airlines Logo
5:13 am - 10:58 am
FLO
-
BOS
5h 45m2 stops
$507American Airlines
Sat, Apr 25 - Sun, May 3
American Airlines Logo
5:15 am - 10:02 am
BOS
-
FLO
4h 47m1 stop
American Airlines Logo
5:13 am - 11:27 am
FLO
-
BOS
6h 14m2 stops
$511American Airlines
Sun, Apr 26 - Sat, May 2

American Airlines flights from Boston to Florence, South Carolina

Our best American Airlines deals on Boston to Florence, South Carolina flight tickets
American Airlines
Jan 6
BOS6:23 pmBoston Logan Intl
4h 20m
1 stop
FLO10:43 pmFlorence
Jan 10
FLO5:36 pmFlorence
4h 46m
1 stop
BOS10:22 pmBoston Logan Intl
$339
Find similar
American Airlines
Jan 6
BOS4:20 pmBoston Logan Intl
6h 23m
2 stops
FLO10:43 pmFlorence
Jan 10
FLO6:15 amFlorence
4h 14m
1 stop
BOS10:29 amBoston Logan Intl
$344
Find similar
American Airlines
Jan 6
BOS9:52 amBoston Logan Intl
7h 17m
2 stops
FLO5:09 pmFlorence
Jan 10
FLO6:15 amFlorence
10h 51m
2 stops
BOS5:06 pmBoston Logan Intl
$349
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Boston to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Boston to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 1/6

6:23 pm-10:43 pm

1 stop4h 20m

Florence

Sat 1/10

5:36 pm-10:22 pm

1 stop4h 46m

$339

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 1/6

4:20 pm-10:43 pm

2 stops6h 23m

Florence

Sat 1/10

6:15 am-10:29 am

1 stop4h 14m

$344

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 1/6

9:52 am-5:09 pm

2 stops7h 17m

Florence

Sat 1/10

6:15 am-5:06 pm

2 stops10h 51m

$349

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 4/25

9:00 am-2:10 pm

1 stop5h 10m

Florence

Sat 5/2

2:33 pm-8:09 pm

1 stop5h 36m

$419

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 4/25

5:17 am-2:10 pm

2 stops8h 53m

Florence

Sat 5/2

2:33 pm-6:26 pm

1 stop3h 53m

$424

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 4/25

5:17 am-2:10 pm

2 stops8h 53m

Florence

Sat 5/2

2:33 pm-9:08 pm

2 stops6h 35m

$429

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 4/25

7:23 pm-11:41 pm

1 stop4h 18m

Florence

Sun 5/3

2:33 pm-8:09 pm

1 stop5h 36m

$502

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 4/26

9:00 am-2:10 pm

1 stop5h 10m

Florence

Sat 5/2

5:13 am-10:58 am

1 stop5h 45m

$506

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sat 4/25

7:23 pm-11:41 pm

1 stop4h 18m

Florence

Sun 5/3

5:13 am-10:58 am

2 stops5h 45m

$507

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Sun 4/26

5:15 am-10:02 am

1 stop4h 47m

Florence

Sat 5/2

5:13 am-11:27 am

2 stops6h 14m

$511

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Boston to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Boston is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $318. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Boston because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $558.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the afternoon. momondo users have found flights departing from Boston to Florence, South Carolina in the afternoon for as low as $388. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $418 per ticket.

When to book flights from Boston to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Boston to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Boston to Florence, South Carolina (BOS to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Boston to Florence, South Carolina

Fastest flight time

4h 20m

Direct flights

None
The fastest flight from Boston to Florence, South Carolina takes 4h 20m
There are no direct flights from Boston to Florence, South Carolina. There are no popular flight routes from Boston to Florence, South Carolina.
Search flight deals

  • How far is Boston Logan Intl to Florence by plane?

    The distance between Boston Logan Intl and Florence is about 734.3 mi. Flights usually cover this in 4h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Boston Logan Intl Airport to Florence Airport?

    Prices for flights from Boston Logan Intl Airport to Florence Airport were last updated today.

  • How many operators does momondo search for flights from Boston Logan Intl Airport to Florence Airport?

  • How old do you have to be to fly from Boston Logan Intl Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Boston Logan Intl Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents you'll need for your trip to Florence Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Florence Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Boston to Florence, South Carolina?

Best airlines flying from Boston to Florence, South Carolina

Compare and see reviews for airlines that fly from Boston to Florence, South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $330Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Boston to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Boston to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Boston to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Boston with this policy.

How can momondo help me find flights from Boston to Florence?

Once you have performed a search for Boston to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Boston to Florence right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Boston to Florence now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florence and let you know when they change.

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