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Cheap flights from Appleton to South America from $758

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Appleton to South America departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Appleton to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:15 am - 12:30 amATW-UIO
41h 15m2 stops
United Airlines Logo
1:35 am - 4:48 pmUIO-ATW
16h 13m2 stops
$758United Airlines
Find Deal
Sun, Jan 4 - Fri, Jan 23
Delta Logo
5:41 am - 6:59 pmATW-UIO
13h 18m1 stop
Delta Logo
12:55 am - 8:45 pmUIO-ATW
19h 50m2 stops
$869Delta
Find Deal
Sat, Oct 25 - Mon, Oct 27
Delta Logo
5:41 am - 6:59 pmATW-UIO
13h 18m1 stop
Delta Logo
12:55 am - 9:35 pmUIO-ATW
20h 40m1 stop
$876Delta
Find Deal
Sat, Oct 25 - Mon, Oct 27

Delta flights from Appleton to South America

Our best Delta deals on Appleton to South America flight tickets
Delta
Oct 25
ATW5:41 amAppleton Intl
13h 18m
1 stop
UIO6:59 pmQuito Mariscal Sucr
Oct 27
UIO12:55 amQuito Mariscal Sucr
19h 50m
2 stops
ATW8:45 pmAppleton Intl
$869
Find similar
Delta
Oct 25
ATW5:41 amAppleton Intl
13h 18m
1 stop
UIO6:59 pmQuito Mariscal Sucr
Oct 27
UIO12:55 amQuito Mariscal Sucr
20h 40m
1 stop
ATW9:35 pmAppleton Intl
$876
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Appleton to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 8, 2025.
Use the filters below to find and compare flights from Appleton to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

AppletonQuito

ATW - UIO

ATWUIO

Appleton Intl

Sun 1/4

6:15 am-12:30 am

2 stops41h 15m

Quito Mariscal Sucr

Fri 1/23

1:35 am-4:48 pm

2 stops16h 13m

$758

AppletonQuito

ATW - UIO

ATWUIO

Appleton Intl

Sat 10/25

5:41 am-6:59 pm

1 stop13h 18m

Quito Mariscal Sucr

Mon 10/27

12:55 am-8:45 pm

2 stops19h 50m

$869

AppletonQuito

ATW - UIO

ATWUIO

Appleton Intl

Sat 10/25

5:41 am-6:59 pm

1 stop13h 18m

Quito Mariscal Sucr

Mon 10/27

12:55 am-9:35 pm

1 stop20h 40m

$876

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Appleton to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Appleton to South America is on a Wednesday when prices can be found for as low as $807. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Appleton to South America for around $1,299.

Can stopping save me money on Appleton to South America flights?

You could potentially save up to 41% on your flight if you consider stops on a Appleton to South America flight.

Cheap Appleton to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Appleton to South America

Direct flights

None
There are no direct flights from Appleton to South America. There are no popular flight routes from Appleton to South America.
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  • When did momondo last update prices for flights from Appleton Intl Airport to South America?

    Prices for flights from Appleton Intl Airport to South America are updated daily.

  • How old do you have to be to fly from Appleton Intl Airport to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Appleton Intl Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Appleton to South America

Compare and see reviews for airlines that fly from Appleton to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $669Free CancellationRating
7.9
7,969 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Appleton to South America?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Appleton to South America. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Appleton to South America with flexible booking policies on momondo?

momondo does allow users to show only those flights to South America from Appleton which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Appleton to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Appleton to South America.

I’m not ready to book a flight from Appleton to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Appleton are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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