What is the cheapest airline that flies from Amarillo to South Carolina?

Southwest and American Airlines are the most popular carriers operating from Amarillo to South Carolina

When did momondo last update prices for flights from Amarillo Airport to South Carolina?

Prices for flights from Amarillo Airport to South Carolina refresh daily.

How many operators does momondo search for flights from Amarillo Airport to South Carolina?

As of April 2026, there is 1 operator available to choose from for flights from Amarillo Airport to South Carolina.

How old do you have to be to fly from Amarillo Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Amarillo Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$249 Cheap Flights from Amarillo to South Carolina in 2026

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Find the cheapest flights from Amarillo to South Carolina

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:25 pm - 6:50 pm

AMA

CHS

5h 25m

1 stop

6:25 am - 2:40 pm

CHS

AMA

9h 15m

2 stops

$452Southwest

Sat, Jul 11 - Fri, Jul 17

9:00 am - 4:11 pm

AMA

CHS

6h 11m

1 stop

5:12 pm - 10:34 pm

CHS

AMA

6h 22m

1 stop

$457United Airlines

Tue, Apr 28 - Wed, Apr 29

3:04 pm - 9:59 pm

AMA

CHS

5h 55m

1 stop

11:22 am - 10:34 pm

CHS

AMA

12h 12m

2 stops

$462United Airlines

Tue, Apr 28 - Wed, Apr 29

9:00 am - 6:59 pm

AMA

CHS

8h 59m

2 stops

6:30 am - 4:40 pm

CHS

AMA

11h 10m

2 stops

$468United Airlines

Tue, Apr 28 - Wed, Apr 29

12:25 pm - 6:50 pm

AMA

CHS

5h 25m

1 stop

3:15 pm - 11:10 pm

CHS

AMA

8h 55m

1 stop

$472Southwest

Sat, Jul 11 - Fri, Jul 17

3:04 pm - 9:59 pm

AMA

CHS

5h 55m

1 stop

5:12 pm - 10:34 pm

CHS

AMA

6h 22m

1 stop

$477United Airlines

Tue, Apr 28 - Wed, Apr 29

5:00 am - 6:40 pm

AMA

CHS

12h 40m

1 stop

7:30 pm - 11:59 pm

CHS

AMA

5h 29m

1 stop

$497American Airlines

Wed, May 13 - Mon, May 18

6:00 am - 1:23 pm

AMA

CAE

6h 23m

1 stop

7:21 pm - 11:59 pm

CAE

AMA

5h 38m

1 stop

$507American Airlines

Wed, May 27 - Wed, Jun 3

6:00 am - 1:23 pm

AMA

CAE

6h 23m

1 stop

4:09 pm - 11:59 pm

CAE

AMA

8h 50m

2 stops

$512American Airlines

Wed, May 27 - Wed, Jun 3

1:17 pm - 6:51 pm

AMA

CAE

4h 34m

1 stop

7:21 pm - 11:59 pm

CAE

AMA

5h 38m

1 stop

$648American Airlines

Fri, May 22 - Mon, May 25

Southwest flights from Amarillo to South Carolina

Our best Southwest deals on Amarillo to South Carolina flight tickets

Southwest

Jul 11

AMA12:25 pmAmarillo

5h 25m

1 stop

CHS6:50 pmCharleston

Jul 17

CHS6:25 amCharleston

9h 15m

2 stops

AMA2:40 pmAmarillo

$452

Southwest

Jul 11

AMA12:25 pmAmarillo

5h 25m

1 stop

CHS6:50 pmCharleston

Jul 17

CHS3:15 pmCharleston

8h 55m

1 stop

AMA11:10 pmAmarillo

$472

Southwest

May 13

AMA11:40 amAmarillo

5h 55m

1 stop

CHS6:35 pmCharleston

May 18

CHS3:50 pmCharleston

8h 35m

2 stops

AMA11:25 pmAmarillo

$492

United Airlines flights from Amarillo to South Carolina

Our best United Airlines deals on Amarillo to South Carolina flight tickets

United Airlines

Apr 28

AMA9:00 amAmarillo

6h 11m

1 stop

CHS4:11 pmCharleston

Apr 29

CHS5:12 pmCharleston

6h 22m

1 stop

AMA10:34 pmAmarillo

$457

United Airlines

Apr 28

AMA3:04 pmAmarillo

5h 55m

1 stop

CHS9:59 pmCharleston

Apr 29

CHS11:22 amCharleston

12h 12m

2 stops

AMA10:34 pmAmarillo

$462

United Airlines

Apr 28

AMA9:00 amAmarillo

8h 59m

2 stops

CHS6:59 pmCharleston

Apr 29

CHS6:30 amCharleston

11h 10m

2 stops

AMA4:40 pmAmarillo

$468

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Sat 7/11

12:25 pm-6:50 pm

1 stop5h 25m

Charleston

Fri 7/17

6:25 am-2:40 pm

2 stops9h 15m

$452

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 4/28

9:00 am-4:11 pm

1 stop6h 11m

Charleston

Wed 4/29

5:12 pm-10:34 pm

1 stop6h 22m

$457

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 4/28

3:04 pm-9:59 pm

1 stop5h 55m

Charleston

Wed 4/29

11:22 am-10:34 pm

2 stops12h 12m

$462

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 4/28

9:00 am-6:59 pm

2 stops8h 59m

Charleston

Wed 4/29

6:30 am-4:40 pm

2 stops11h 10m

$468

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Sat 7/11

12:25 pm-6:50 pm

1 stop5h 25m

Charleston

Fri 7/17

3:15 pm-11:10 pm

1 stop8h 55m

$472

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 4/28

3:04 pm-9:59 pm

1 stop5h 55m

Charleston

Wed 4/29

5:12 pm-10:34 pm

1 stop6h 22m

$477

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Wed 5/13

5:00 am-6:40 pm

1 stop12h 40m

Charleston

Mon 5/18

7:30 pm-11:59 pm

1 stop5h 29m

$497

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 5/27

6:00 am-1:23 pm

1 stop6h 23m

Columbia Metropolitan

Wed 6/3

7:21 pm-11:59 pm

1 stop5h 38m

$507

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 5/27

6:00 am-1:23 pm

1 stop6h 23m

Columbia Metropolitan

Wed 6/3

4:09 pm-11:59 pm

2 stops8h 50m

$512

Quickest round-trip

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Fri 5/22

1:17 pm-6:51 pm

1 stop4h 34m

Columbia Metropolitan

Mon 5/25

7:21 pm-11:59 pm

1 stop5h 38m

$648

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first

How to get the cheapest flight ticket from Amarillo to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Amarillo to South Carolina flights?

You could potentially save up to 1% on your flight if you consider stops on a Amarillo to South Carolina flight.

Cheap Amarillo to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Amarillo to South Carolina

Fastest flight time	5h 55m
Direct flights	None

The fastest flight from Amarillo to South Carolina takes 5h 55m

There are no direct flights from Amarillo to South Carolina. There are no popular flight routes from Amarillo to South Carolina.

Search flight deals

Frequently asked questions about flying from Amarillo to South Carolina

When did momondo last update prices for flights from Amarillo Airport to South Carolina?
Prices for flights from Amarillo Airport to South Carolina refresh daily.
How many operators does momondo search for flights from Amarillo Airport to South Carolina?
As of April 2026, there is 1 operator available to choose from for flights from Amarillo Airport to South Carolina.
How old do you have to be to fly from Amarillo Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Amarillo Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Amarillo to South Carolina

Compare and see reviews for airlines that fly from Amarillo to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $370	Free Cancellation	Rating 7.1 11,548 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Amarillo to South Carolina?

It is quick and easy to find Amarillo to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Amarillo to South Carolina with flexible booking policies on momondo?

Yes. All flights to South Carolina from Amarillo on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Amarillo to South Carolina?

Once you have performed a search for Amarillo to South Carolina flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Amarillo to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Amarillo and alert you when they change.