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Cheap flights from Houston Hobby Airport to South America from $320

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston Hobby Airport to South America departing on 1/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston Hobby Airport to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:31 pm - 12:10 pmHOU-CTG
17h 39m2 stops
American Airlines Logo
1:55 pm - 9:30 amCTG-HOU
19h 35m2 stops
$499American Airlines
Find Deal
Sun, May 3 - Tue, May 12
American Airlines Logo
8:27 pm - 2:10 pmHOU-CTG
17h 43m2 stops
American Airlines Logo
3:25 pm - 9:30 amCTG-HOU
18h 05m2 stops
$519American Airlines
Find Deal
Fri, Apr 24 - Fri, May 1
American Airlines Logo
6:36 pm - 3:30 pmHOU-CTG
19h 54m2 stops
American Airlines Logo
4:30 pm - 10:05 amCTG-HOU
18h 35m2 stops
$554American Airlines
Find Deal
Sun, Jan 11 - Sat, Jan 17
LATAM Airlines Logo
6:00 am - 9:00 pmHOU-CLO
14h 00m2 stops
LATAM Airlines Logo
6:22 am - 10:35 pmCLO-HOU
17h 13m2 stops
$709LATAM Airlines
Find Deal
Sat, Dec 6 - Tue, Feb 3
LATAM Airlines Logo
6:00 am - 2:13 pmHOU-CLO
31h 13m2 stops
LATAM Airlines Logo
10:47 pm - 10:35 pmCLO-HOU
24h 48m2 stops
$716LATAM Airlines
Find Deal
Tue, Dec 9 - Tue, Jan 13
Delta Logo
6:00 am - 11:16 pmHOU-CTG
16h 16m2 stops
Delta Logo
3:32 pm - 10:48 pmCTG-HOU
8h 16m1 stop
$722Delta
Find Deal
Wed, Dec 3 - Thu, Dec 11
Delta Logo
6:00 am - 8:01 pmHOU-CTG
13h 01m2 stops
Delta Logo
5:05 am - 10:48 pmCTG-HOU
18h 43m2 stops
$725Delta
Find Deal
Wed, Nov 26 - Wed, Dec 3
Multiple Airlines Logo
5:35 am - 6:20 amHOU-EZE
21h 45m2 stops
Multiple Airlines Logo
11:00 am - 4:12 pmEZE-HOU
32h 12m2 stops
$1,189Multiple Airlines
Find Deal
Mon, Jan 5 - Mon, Jan 12
Multiple Airlines Logo
1:06 pm - 9:00 amHOU-EZE
16h 54m1 stop
Multiple Airlines Logo
2:45 pm - 9:32 amEZE-HOU
20h 47m2 stops
$1,346Multiple Airlines
Find Deal
Fri, Mar 6 - Sat, Mar 14
British Airways Logo
8:20 pm - 7:59 pmHOU-UIO
22h 39m2 stops
British Airways Logo
8:27 am - 7:50 pmUIO-HOU
12h 23m2 stops
$1,437British Airways
Find Deal
Sun, Nov 23 - Wed, Nov 26

American Airlines flights from Houston Hobby Airport to South America

Our best American Airlines deals on Houston Hobby Airport to South America flight tickets
American Airlines
May 3
HOU6:31 pmHouston Hobby
17h 39m
2 stops
CTG12:10 pmCartagena Rafael Nunez
May 12
CTG1:55 pmCartagena Rafael Nunez
19h 35m
2 stops
HOU9:30 amHouston Hobby
$499
Find similar
American Airlines
Apr 24
HOU8:27 pmHouston Hobby
17h 43m
2 stops
CTG2:10 pmCartagena Rafael Nunez
May 1
CTG3:25 pmCartagena Rafael Nunez
18h 05m
2 stops
HOU9:30 amHouston Hobby
$519
Find similar
American Airlines
Jan 11
HOU6:36 pmHouston Hobby
19h 54m
2 stops
CTG3:30 pmCartagena Rafael Nunez
Jan 17
CTG4:30 pmCartagena Rafael Nunez
18h 35m
2 stops
HOU10:05 amHouston Hobby
$554
Find similar

Delta flights from Houston Hobby Airport to South America

Our best Delta deals on Houston Hobby Airport to South America flight tickets
Delta
Dec 3
HOU6:00 amHouston Hobby
16h 16m
2 stops
CTG11:16 pmCartagena Rafael Nunez
Dec 11
CTG3:32 pmCartagena Rafael Nunez
8h 16m
1 stop
HOU10:48 pmHouston Hobby
$722
Find similar
Delta
Nov 26
HOU6:00 amHouston Hobby
13h 01m
2 stops
CTG8:01 pmCartagena Rafael Nunez
Dec 3
CTG5:05 amCartagena Rafael Nunez
18h 43m
2 stops
HOU10:48 pmHouston Hobby
$725
Find similar
Delta
Apr 27
HOU6:00 amHouston Hobby
14h 15m
2 stops
LIM8:15 pmLima J Chavez Intl
May 5
LIM11:20 pmLima J Chavez Intl
12h 50m
1 stop
HOU12:10 pmHouston Hobby
$744
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston Hobby Airport to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Houston Hobby Airport to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Sun 5/3

6:31 pm-12:10 pm

2 stops17h 39m

Cartagena Rafael Nunez

Tue 5/12

1:55 pm-9:30 am

2 stops19h 35m

$499

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Fri 4/24

8:27 pm-2:10 pm

2 stops17h 43m

Cartagena Rafael Nunez

Fri 5/1

3:25 pm-9:30 am

2 stops18h 05m

$519

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Sun 1/11

6:36 pm-3:30 pm

2 stops19h 54m

Cartagena Rafael Nunez

Sat 1/17

4:30 pm-10:05 am

2 stops18h 35m

$554

HoustonCali

HOU - CLO

HOUCLO

Houston Hobby

Sat 12/6

6:00 am-9:00 pm

2 stops14h 00m

Cali Alfonso B. Aragon Intl

Tue 2/3

6:22 am-10:35 pm

2 stops17h 13m

$709

HoustonCali

HOU - CLO

HOUCLO

Houston Hobby

Tue 12/9

6:00 am-2:13 pm

2 stops31h 13m

Cali Alfonso B. Aragon Intl

Tue 1/13

10:47 pm-10:35 pm

2 stops24h 48m

$716

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Wed 12/3

6:00 am-11:16 pm

2 stops16h 16m

Cartagena Rafael Nunez

Thu 12/11

3:32 pm-10:48 pm

1 stop8h 16m

$722

HoustonCartagena

HOU - CTG

HOUCTG

Houston Hobby

Wed 11/26

6:00 am-8:01 pm

2 stops13h 01m

Cartagena Rafael Nunez

Wed 12/3

5:05 am-10:48 pm

2 stops18h 43m

$725

HoustonBuenos Aires

HOU - EZE

HOUEZE

Houston Hobby

Mon 1/5

5:35 am-6:20 am

2 stops21h 45m

Buenos Aires Ministro Pistarini

Mon 1/12

11:00 am-4:12 pm

2 stops32h 12m

$1,189

HoustonBuenos Aires

HOU - EZE

HOUEZE

Houston Hobby

Fri 3/6

1:06 pm-9:00 am

1 stop16h 54m

Buenos Aires Ministro Pistarini

Sat 3/14

2:45 pm-9:32 am

2 stops20h 47m

$1,346

HoustonQuito

HOU - UIO

HOUUIO

Houston Hobby

Sun 11/23

8:20 pm-7:59 pm

2 stops22h 39m

Quito Mariscal Sucr

Wed 11/26

8:27 am-7:50 pm

2 stops12h 23m

$1,437

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Houston Hobby Airport to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, May is the cheapest month to fly from Houston Hobby Airport to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $597. If you aren’t able to travel during the month of May, then book flights to South America from Houston Hobby Airport during July instead. Flights to South America in July, while not as cheap as those in May, still average around $686.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Houston Hobby Airport to South America is on a Wednesday when prices can be found for as low as $766. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Houston Hobby Airport to South America for around $928.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Houston Hobby Airport to South America flights are usually those with departure times in the evening. Our users have found flights to South America in the evening for as low as $823. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,190 on average. Flights to South America from Houston Hobby Airport at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Houston Hobby Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $791 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Houston Hobby Airport for as low as $567 on momondo.

Can stopping save me money on Houston Hobby Airport to South America flights?

You could potentially save up to 3% on your flight if you consider stops on a Houston Hobby Airport to South America flight.

Cheap Houston Hobby Airport to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston Hobby Airport to South America

Direct flights

None
There are no direct flights from Houston Hobby Airport to South America. There are no popular flight routes from Houston Hobby Airport to South America.
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  • When did momondo last update prices for flights from Houston Hobby Airport to South America?

    Prices for flights from Houston Hobby Airport to South America refresh daily.

  • How many operators does momondo search for flights from Houston Hobby Airport to South America?

  • How old do you have to be to fly from Houston Hobby Airport to South America?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Houston Hobby Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Houston Hobby Airport to South America

Compare and see reviews for airlines that fly from Houston Hobby Airport to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $201Free CancellationRating
6.3
8,113 reviews
Search Spirit Airlines flights
AviancaPriceFrom $310Free CancellationRating
6.6
2,471 reviews
Search Avianca flights
VolarisPriceFrom $342Free CancellationRating
6.7
1,151 reviews
Search Volaris flights
American AirlinesPriceFrom $578Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $587Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
DeltaPriceFrom $724Free CancellationRating
7.9
8,004 reviews
Search Delta flights
United AirlinesPriceFrom $739Free CancellationRating
7.4
9,001 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $785Free CancellationRating
7.5
1,874 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Houston.

Can I find flights from Houston to South America with flexible booking policies on momondo?

momondo does allow users to show only those flights to South America from Houston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Houston to South America?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Houston to South America.

I’m not ready to book a flight from Houston to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Houston and alert you when they change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

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