What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from St. Louis according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 4 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Lambert-St Louis to South America?

American Airlines, Delta, and Air Canada are the most popular carriers operating from Lambert-St Louis to South America

When did momondo last update prices for flights from Lambert-St Louis Airport to South America?

Prices for flights from Lambert-St Louis Airport to South America were last updated today.

How many operators does momondo search for flights from Lambert-St Louis Airport to South America?

The number of operators available for flights from Lambert-St Louis Airport to South America is 4 as of June 2026.

How old do you have to be to fly from Lambert-St Louis Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$268 Cheap Flights from St. Louis to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:42 pm - 2:15 pm

STL

CTG

21h 33m

1 stop

3:25 pm - 11:39 pm

CTG

STL

9h 14m

1 stop

$537Delta

Wed, Nov 4 - Tue, Mar 2

8:07 pm - 2:15 pm

STL

CTG

18h 08m

2 stops

1:35 pm - 9:24 am

CTG

STL

19h 49m

2 stops

$572American Airlines

Fri, Aug 21 - Tue, Aug 25

11:35 am - 12:35 pm

STL

CTG

25h 00m

1 stop

1:35 pm - 10:40 pm

CTG

STL

9h 05m

1 stop

$580American Airlines

Fri, Aug 21 - Tue, Aug 25

6:00 am - 2:15 pm

STL

CTG

7h 15m

1 stop

3:25 pm - 11:39 pm

CTG

STL

9h 14m

1 stop

$608Delta

Thu, Nov 5 - Wed, Nov 11

8:00 am - 9:10 pm

STL

MDE

13h 10m

2 stops

9:45 am - 10:30 pm

MDE

STL

12h 45m

1 stop

$654United Airlines

Thu, Sep 10 - Mon, Sep 14

8:00 am - 9:10 pm

STL

MDE

13h 10m

2 stops

9:45 am - 11:57 am

MDE

STL

26h 12m

2 stops

$659United Airlines

Thu, Sep 10 - Mon, Sep 14

6:00 am - 8:20 pm

STL

LIM

13h 20m

2 stops

12:00 pm - 8:12 am

LIM

STL

21h 12m

1 stop

$734LATAM Airlines

Mon, Nov 9 - Mon, Nov 16

6:00 am - 8:20 pm

STL

LIM

14h 20m

2 stops

12:05 pm - 11:37 pm

LIM

STL

11h 32m

1 stop

$756LATAM Airlines

Wed, Sep 2 - Fri, Sep 11

5:33 am - 11:05 pm

STL

GRU

39h 32m

2 stops

6:00 am - 5:23 pm

GRU

STL

37h 23m

2 stops

$1,022GOL

Thu, Oct 8 - Mon, Oct 19

11:35 am - 10:45 am

STL

VCP

21h 10m

2 stops

6:00 pm - 11:46 pm

VCP

STL

31h 46m

2 stops

$1,141GOL

Wed, Sep 2 - Wed, Sep 16

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LATAM Airlines flights from St. Louis to South America

Our best LATAM Airlines deals on St. Louis to South America flight tickets

LATAM Airlines

Jul 10

STL6:58 pmLambert-St Louis

18h 11m

1 stop

CTG1:09 pmCartagena Rafael Nunez

Jul 18

CTG2:30 pmCartagena Rafael Nunez

17h 49m

1 stop

STL8:19 amLambert-St Louis

$684

LATAM Airlines

Oct 24

STL6:00 amLambert-St Louis

17h 35m

2 stops

CTG11:35 pmCartagena Rafael Nunez

Oct 28

CTG5:05 amCartagena Rafael Nunez

29h 43m

2 stops

STL10:48 amLambert-St Louis

$703

LATAM Airlines

Nov 9

STL6:00 amLambert-St Louis

13h 20m

2 stops

LIM8:20 pmLima J Chavez Intl

Nov 16

LIM12:00 pmLima J Chavez Intl

21h 12m

1 stop

STL8:12 amLambert-St Louis

$734

American Airlines flights from St. Louis to South America

Our best American Airlines deals on St. Louis to South America flight tickets

American Airlines

Aug 21

STL8:07 pmLambert-St Louis

18h 08m

2 stops

CTG2:15 pmCartagena Rafael Nunez

Aug 25

CTG1:35 pmCartagena Rafael Nunez

19h 49m

2 stops

STL9:24 amLambert-St Louis

$572

American Airlines

Aug 21

STL11:35 amLambert-St Louis

25h 00m

1 stop

CTG12:35 pmCartagena Rafael Nunez

Aug 25

CTG1:35 pmCartagena Rafael Nunez

9h 05m

1 stop

STL10:40 pmLambert-St Louis

$580

American Airlines

Jul 10

STL6:13 pmLambert-St Louis

20h 04m

2 stops

CTG2:17 pmCartagena Rafael Nunez

Jul 18

CTG3:17 pmCartagena Rafael Nunez

19h 18m

2 stops

STL10:35 amLambert-St Louis

$593

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

Wed 11/4

3:42 pm-2:15 pm

1 stop21h 33m

Cartagena Rafael Nunez

Tue 3/2

3:25 pm-11:39 pm

1 stop9h 14m

$537

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

Fri 8/21

8:07 pm-2:15 pm

2 stops18h 08m

Cartagena Rafael Nunez

Tue 8/25

1:35 pm-9:24 am

2 stops19h 49m

$572

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

Fri 8/21

11:35 am-12:35 pm

1 stop25h 00m

Cartagena Rafael Nunez

Tue 8/25

1:35 pm-10:40 pm

1 stop9h 05m

$580

Quickest round-trip

St. LouisCartagena

STL - CTG

STLCTG

Lambert-St Louis

Thu 11/5

6:00 am-2:15 pm

1 stop7h 15m

Cartagena Rafael Nunez

Wed 11/11

3:25 pm-11:39 pm

1 stop9h 14m

$608

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 9/10

8:00 am-9:10 pm

2 stops13h 10m

Medellín Jose Maria Cordova Intl

Mon 9/14

9:45 am-10:30 pm

1 stop12h 45m

$654

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 9/10

8:00 am-9:10 pm

2 stops13h 10m

Medellín Jose Maria Cordova Intl

Mon 9/14

9:45 am-11:57 am

2 stops26h 12m

$659

St. LouisLima

STL - LIM

STLLIM

Lambert-St Louis

Mon 11/9

6:00 am-8:20 pm

2 stops13h 20m

Lima J Chavez Intl

Mon 11/16

12:00 pm-8:12 am

1 stop21h 12m

$734

St. LouisLima

STL - LIM

STLLIM

Lambert-St Louis

Wed 9/2

6:00 am-8:20 pm

2 stops14h 20m

Lima J Chavez Intl

Fri 9/11

12:05 pm-11:37 pm

1 stop11h 32m

$756

St. LouisSao Paulo

STL - GRU

STLGRU

Lambert-St Louis

Thu 10/8

5:33 am-11:05 pm

2 stops39h 32m

Sao Paulo Guarulhos Intl

Mon 10/19

6:00 am-5:23 pm

2 stops37h 23m

$1,022

St. LouisSao Paulo

STL - VCP

STLVCP

Lambert-St Louis

Wed 9/2

11:35 am-10:45 am

2 stops21h 10m

Sao Paulo Viracopos

Wed 9/16

6:00 pm-11:46 pm

2 stops31h 46m

$1,141

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, July is the cheapest month to fly from St. Louis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $178. If you aren’t able to travel during the month of July, then book flights to South America from St. Louis during June instead. Flights to South America in June, while not as cheap as those in July, still average around $185.

How far in advance should I book a flight from St. Louis to South America?

You are more likely to see cheaper flights to South America from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $841 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from St. Louis for as low as $671 on momondo.

Can stopping save me money on St. Louis to South America flights?

You could potentially save up to 7% on your flight if you consider stops on a St. Louis to South America flight.

Cheap St. Louis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to South America

Fastest flight time	7h 09m
Direct flights	None

The fastest flight from St. Louis to South America takes 7h 09m

There are no direct flights from St. Louis to South America. There are no popular flight routes from St. Louis to South America.

Search flight deals

Frequently asked questions about flying from St. Louis to South America

When did momondo last update prices for flights from Lambert-St Louis Airport to South America?
Prices for flights from Lambert-St Louis Airport to South America were last updated today.
How many operators does momondo search for flights from Lambert-St Louis Airport to South America?
The number of operators available for flights from Lambert-St Louis Airport to South America is 4 as of June 2026.
How old do you have to be to fly from Lambert-St Louis Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from St. Louis to South America

Compare and see reviews for airlines that fly from St. Louis to South America with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $536	Free Cancellation	Rating 7.4 1,932 reviews	Search LATAM Airlines flights
Delta	PriceFrom $563	Free Cancellation	Rating 7.9 8,406 reviews	Search Delta flights
American Airlines	PriceFrom $574	Free Cancellation	Rating 7.1 11,649 reviews	Search American Airlines flights
United Airlines	PriceFrom $615	Free Cancellation	Rating 7.4 9,816 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from St. Louis to South America. momondo saves you time and could save you money on your trip.

Can I find flights from St. Louis to South America with flexible booking policies on momondo?

momondo does allow users to show only those flights to South America from St. Louis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from St. Louis to South America?

Once all potential St. Louis to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from St. Louis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.