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Cheap flights from Spain to Panama City from $731

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Spain to Panama City departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Spain to Panama City

Recent round-trip flight deals from Spain to Panama City

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:00 am - 5:12 pm
MAD
-
ECP
18h 12m2 stops
Multiple Airlines Logo
4:45 pm - 5:40 pm
ECP
-
MAD
17h 55m2 stops
$731Multiple Airlines
Fri, Jan 23 - Tue, Jan 27
American Airlines Logo
1:00 pm - 2:54 pm
MAD
-
ECP
32h 54m1 stop
American Airlines Logo
7:02 am - 9:25 am
ECP
-
MAD
19h 23m1 stop
$739American Airlines
Fri, Jan 23 - Tue, Jan 27
American Airlines Logo
1:00 pm - 2:54 pm
MAD
-
ECP
32h 54m1 stop
American Airlines Logo
12:03 pm - 10:00 am
ECP
-
MAD
14h 57m2 stops
$740American Airlines
Fri, Jan 23 - Tue, Jan 27
Delta Logo
12:40 pm - 10:46 pm
MAD
-
ECP
17h 06m2 stops
Delta Logo
7:05 pm - 7:35 pm
ECP
-
MAD
17h 30m2 stops
$782Delta
Wed, Jun 10 - Mon, Sep 7
American Airlines Logo
1:00 pm - 11:41 pm
MAD
-
ECP
17h 41m1 stop
American Airlines Logo
1:14 pm - 9:35 am
ECP
-
MAD
13h 21m1 stop
$790American Airlines
Wed, Jun 10 - Mon, Sep 7
American Airlines Logo
12:55 am - 3:08 pm
MAD
-
ECP
21h 13m1 stop
American Airlines Logo
1:19 pm - 8:50 am
ECP
-
MAD
12h 31m1 stop
$904American Airlines
Wed, Feb 18 - Mon, Feb 23
United Airlines Logo
11:15 am - 1:09 pm
MAD
-
ECP
56h 54m2 stops
United Airlines Logo
11:10 am - 10:50 am
ECP
-
MAD
40h 40m3 stops
$1,236United Airlines
Wed, Jun 10 - Mon, Sep 7

American Airlines flights from Spain to Panama City, Florida

Our best American Airlines deals on Spain to Panama City, Florida flight tickets
American Airlines
Jan 23
MAD1:00 pmMadrid Barajas
32h 54m
1 stop
ECP2:54 pmPanama City NW Florida Beaches
Jan 27
ECP7:02 amPanama City NW Florida Beaches
19h 23m
1 stop
MAD9:25 amMadrid Barajas
$739
Find similar
American Airlines
Jan 23
MAD1:00 pmMadrid Barajas
32h 54m
1 stop
ECP2:54 pmPanama City NW Florida Beaches
Jan 27
ECP12:03 pmPanama City NW Florida Beaches
14h 57m
2 stops
MAD10:00 amMadrid Barajas
$740
Find similar
American Airlines
Jun 10
MAD1:00 pmMadrid Barajas
17h 41m
1 stop
ECP11:41 pmPanama City NW Florida Beaches
Sep 7
ECP1:14 pmPanama City NW Florida Beaches
13h 21m
1 stop
MAD9:35 amMadrid Barajas
$790
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Spain to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Spain to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 1/23

6:00 am-5:12 pm

2 stops18h 12m

Panama City NW Florida Beaches

Tue 1/27

4:45 pm-5:40 pm

2 stops17h 55m

$731

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 1/23

1:00 pm-2:54 pm

1 stop32h 54m

Panama City NW Florida Beaches

Tue 1/27

7:02 am-9:25 am

1 stop19h 23m

$739

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 1/23

1:00 pm-2:54 pm

1 stop32h 54m

Panama City NW Florida Beaches

Tue 1/27

12:03 pm-10:00 am

2 stops14h 57m

$740

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/10

12:40 pm-10:46 pm

2 stops17h 06m

Panama City NW Florida Beaches

Mon 9/7

7:05 pm-7:35 pm

2 stops17h 30m

$782

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/10

1:00 pm-11:41 pm

1 stop17h 41m

Panama City NW Florida Beaches

Mon 9/7

1:14 pm-9:35 am

1 stop13h 21m

$790

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 2/18

12:55 am-3:08 pm

1 stop21h 13m

Panama City NW Florida Beaches

Mon 2/23

1:19 pm-8:50 am

1 stop12h 31m

$904

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 6/10

11:15 am-1:09 pm

2 stops56h 54m

Panama City NW Florida Beaches

Mon 9/7

11:10 am-10:50 am

3 stops40h 40m

$1,236

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Spain to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Spain to Panama City, Florida flights?

You could potentially save up to 14% on your flight if you consider stops on a Spain to Panama City, Florida flight.

Cheap Spain to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Spain to Panama City, Florida

Fastest flight time

17h 06m

Direct flights

None
The fastest flight from Spain to Panama City, Florida takes 17h 06m
There are no direct flights from Spain to Panama City, Florida. There are no popular flight routes from Spain to Panama City, Florida.
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  • When did momondo last update prices for flights from Spain to Panama City NW Florida Beaches Airport?

    Prices for flights from Spain to Panama City NW Florida Beaches Airport refresh daily.

  • How old do you have to be to fly from Spain to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Spain to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Spain to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Spain to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Spain to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Spain to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Spain to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Spain to Panama City.

I’m not ready to book a flight from Spain to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Spain to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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