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Cheap flights from South Dakota to Myrtle Beach from $279

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Dakota to Myrtle Beach departing on 5/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Dakota to Myrtle Beach

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:15 am - 1:39 pm
FSD
-
MYR
7h 24m1 stop
Delta Logo
2:40 pm - 7:06 pm
MYR
-
FSD
5h 26m1 stop
$279Delta
Wed, May 13 - Wed, May 20
Delta Logo
8:15 am - 1:39 pm
FSD
-
MYR
4h 24m1 stop
Delta Logo
3:40 pm - 10:11 pm
MYR
-
FSD
7h 31m1 stop
$294Delta
Tue, May 5 - Tue, May 12
American Airlines Logo
5:49 am - 11:37 am
FSD
-
MYR
4h 48m1 stop
American Airlines Logo
5:28 am - 12:19 pm
MYR
-
FSD
7h 51m2 stops
$369American Airlines
Wed, May 13 - Wed, May 20
American Airlines Logo
5:49 am - 11:37 am
FSD
-
MYR
4h 48m1 stop
American Airlines Logo
5:28 am - 12:19 pm
MYR
-
FSD
7h 51m2 stops
$394American Airlines
Tue, May 5 - Tue, May 12
American Airlines Logo
1:33 pm - 11:20 pm
FSD
-
MYR
8h 47m2 stops
American Airlines Logo
5:28 am - 11:33 am
MYR
-
FSD
7h 05m2 stops
$424American Airlines
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
7:02 pm - 8:15 am
FSD
-
MYR
36h 13m2 stops
Multiple Airlines Logo
9:10 am - 5:24 pm
MYR
-
FSD
9h 14m1 stop
$434Multiple Airlines
Fri, Feb 20 - Mon, Feb 23
American Airlines Logo
12:19 pm - 11:56 pm
FSD
-
MYR
10h 37m2 stops
American Airlines Logo
9:04 am - 7:06 pm
MYR
-
FSD
11h 02m2 stops
$469American Airlines
Fri, Feb 20 - Mon, Feb 23
Multiple Airlines Logo
6:39 pm - 8:15 am
FSD
-
MYR
12h 36m1 stop
Multiple Airlines Logo
9:10 am - 5:24 pm
MYR
-
FSD
9h 14m1 stop
$510Multiple Airlines
Fri, Feb 20 - Mon, Feb 23
American Airlines Logo
5:49 am - 2:07 pm
FSD
-
MYR
7h 18m2 stops
American Airlines Logo
5:28 am - 12:19 pm
MYR
-
FSD
7h 51m2 stops
$588American Airlines
Wed, May 13 - Wed, May 20
United Airlines Logo
3:11 pm - 12:41 pm
FSD
-
MYR
20h 30m2 stops
United Airlines Logo
2:09 pm - 10:47 am
MYR
-
FSD
21h 38m2 stops
$666United Airlines
Sat, Jan 31 - Wed, Feb 4

Delta flights from South Dakota to Myrtle Beach

Our best Delta deals on South Dakota to Myrtle Beach flight tickets
Delta
May 13
FSD5:15 amSioux Falls Joe Foss Field
7h 24m
1 stop
MYR1:39 pmMyrtle Beach Intl
May 20
MYR2:40 pmMyrtle Beach Intl
5h 26m
1 stop
FSD7:06 pmSioux Falls Joe Foss Field
$279
Find similar
Delta
May 5
FSD8:15 amSioux Falls Joe Foss Field
4h 24m
1 stop
MYR1:39 pmMyrtle Beach Intl
May 12
MYR3:40 pmMyrtle Beach Intl
7h 31m
1 stop
FSD10:11 pmSioux Falls Joe Foss Field
$294
Find similar
Delta
Dec 25
FSD11:06 amSioux Falls Joe Foss Field
8h 11m
2 stops
MYR8:17 pmMyrtle Beach Intl
Dec 29
MYR6:59 pmMyrtle Beach Intl
5h 41m
1 stop
FSD11:40 pmSioux Falls Joe Foss Field
$718
Find similar

American Airlines flights from South Dakota to Myrtle Beach

Our best American Airlines deals on South Dakota to Myrtle Beach flight tickets
American Airlines
May 13
FSD5:49 amSioux Falls Joe Foss Field
4h 48m
1 stop
MYR11:37 amMyrtle Beach Intl
May 20
MYR5:28 amMyrtle Beach Intl
7h 51m
2 stops
FSD12:19 pmSioux Falls Joe Foss Field
$369
Find similar
American Airlines
May 5
FSD5:49 amSioux Falls Joe Foss Field
4h 48m
1 stop
MYR11:37 amMyrtle Beach Intl
May 12
MYR5:28 amMyrtle Beach Intl
7h 51m
2 stops
FSD12:19 pmSioux Falls Joe Foss Field
$394
Find similar
American Airlines
May 5
FSD1:33 pmSioux Falls Joe Foss Field
8h 47m
2 stops
MYR11:20 pmMyrtle Beach Intl
May 12
MYR5:28 amMyrtle Beach Intl
7h 05m
2 stops
FSD11:33 amSioux Falls Joe Foss Field
$424
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Dakota to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from South Dakota to Myrtle Beach that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 5/13

5:15 am-1:39 pm

1 stop7h 24m

Myrtle Beach Intl

Wed 5/20

2:40 pm-7:06 pm

1 stop5h 26m

$279

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 5/5

8:15 am-1:39 pm

1 stop4h 24m

Myrtle Beach Intl

Tue 5/12

3:40 pm-10:11 pm

1 stop7h 31m

$294

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 5/13

5:49 am-11:37 am

1 stop4h 48m

Myrtle Beach Intl

Wed 5/20

5:28 am-12:19 pm

2 stops7h 51m

$369

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 5/5

5:49 am-11:37 am

1 stop4h 48m

Myrtle Beach Intl

Tue 5/12

5:28 am-12:19 pm

2 stops7h 51m

$394

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 5/5

1:33 pm-11:20 pm

2 stops8h 47m

Myrtle Beach Intl

Tue 5/12

5:28 am-11:33 am

2 stops7h 05m

$424

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 2/20

7:02 pm-8:15 am

2 stops36h 13m

Myrtle Beach Intl

Mon 2/23

9:10 am-5:24 pm

1 stop9h 14m

$434

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 2/20

12:19 pm-11:56 pm

2 stops10h 37m

Myrtle Beach Intl

Mon 2/23

9:04 am-7:06 pm

2 stops11h 02m

$469

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 2/20

6:39 pm-8:15 am

1 stop12h 36m

Myrtle Beach Intl

Mon 2/23

9:10 am-5:24 pm

1 stop9h 14m

$510

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 5/13

5:49 am-2:07 pm

2 stops7h 18m

Myrtle Beach Intl

Wed 5/20

5:28 am-12:19 pm

2 stops7h 51m

$588

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 1/31

3:11 pm-12:41 pm

2 stops20h 30m

Myrtle Beach Intl

Wed 2/4

2:09 pm-10:47 am

2 stops21h 38m

$666

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Myrtle Beach from

How to get the cheapest flight ticket from South Dakota to Myrtle Beach

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Myrtle Beach?

Our data shows that Tuesday is the least expensive day to fly to Myrtle Beach. Tickets to fly out on this day can be as low as $432. The most expensive day to fly to Myrtle Beach is Thursday, with ticket prices averaging around $698.

What is the cheapest time of day to depart on your flight to Myrtle Beach?

The cheapest time of day to fly to Myrtle Beach is at noon when flights can be purchased for as low as $547. Flights in the morning are often more expensive with an average ticket price of $568.

Can stopping save me money on South Dakota to Myrtle Beach flights?

You could potentially save up to 88% on your flight if you consider stops on a South Dakota to Myrtle Beach flight.

Cheap South Dakota to Myrtle Beach flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Dakota to Myrtle Beach

Fastest flight time

6h 13m

Direct flights

None
The fastest flight from South Dakota to Myrtle Beach takes 6h 13m
There are no direct flights from South Dakota to Myrtle Beach. There are no popular flight routes from South Dakota to Myrtle Beach.
Search flight deals

  • When did momondo last update prices for flights from South Dakota to Myrtle Beach Intl Airport?

    Prices for flights from South Dakota to Myrtle Beach Intl Airport are updated daily.

  • How many operators does momondo search for flights from South Dakota to Myrtle Beach Intl Airport?

  • How old do you have to be to fly from South Dakota to Myrtle Beach Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Myrtle Beach Intl Airport.

  • What documentation or ID do you need to fly to Myrtle Beach Intl Airport?

    The travel and health documents required for your trip to Myrtle Beach Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Myrtle Beach Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from South Dakota to Myrtle Beach

Compare and see reviews for airlines that fly from South Dakota to Myrtle Beach with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $256Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $261Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
United AirlinesPriceFrom $273Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
North Myrtle Beach
Pawleys Island
Sunset Beach
Ocean Isle Beach
Murrells Inlet
Garden City Beach
Surfside Beach
Conway
Little River
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from South Dakota to Myrtle Beach?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Dakota to Myrtle Beach. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Dakota to Myrtle Beach with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Myrtle Beach from South Dakota with this policy.

How can momondo help me find flights from South Dakota to Myrtle Beach?

momondo helps you find the best flight between South Dakota and Myrtle Beach by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Dakota to Myrtle Beach right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Myrtle Beach, momondo offers a useful price alert feature which will track prices for flights to Myrtle Beach from South Dakota and alert you when they change.

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