How long does it take to fly to Knoxville?

Average flight duration from South Dakota to Knoxville depends on which airport you fly into and out of. Flying from Sioux Falls to Knoxville is 4h 41m on average, while flying from Rapid City to Knoxville is 5h 02m on average. Knoxville is the most popular airport in Knoxville.

What is the cheapest airline that flies from South Dakota to Knoxville McGhee Tyson?

Delta, American Airlines, and Allegiant Air are the most popular carriers operating from South Dakota to Knoxville McGhee Tyson

How many flights depart from South Dakota to Knoxville on average per week?

The number of flights available between South Dakota and Knoxville is 6 per week as of August 2026. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.

What airlines fly to Knoxville?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Knoxville from South Dakota according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 3 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from South Dakota to Knoxville McGhee Tyson Airport?

Prices for flights from South Dakota to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from South Dakota to Knoxville McGhee Tyson Airport?

There are 3 operators available for flights from South Dakota to Knoxville McGhee Tyson Airport as of August 2026.

How old do you have to be to fly from South Dakota to Knoxville McGhee Tyson Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$279 Cheap Flights from South Dakota to Knoxville in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Dakota to Knoxville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:05 am - 2:36 pmRAP Rapid City-TYS Knoxville McGhee Tyson

5h 31m1 stop Denver Intl

10:50 am - 5:03 pmTYS Knoxville McGhee Tyson-RAP Rapid City

8h 13m2 stops Chicago O'Hare Intl Denver Intl

$284United Airlines

Tue, Jan 5 - Tue, Jan 12

11:29 am - 10:02 pmRAP Rapid City-TYS Knoxville McGhee Tyson

8h 33m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

6:40 pm - 10:37 pmTYS Knoxville McGhee Tyson-RAP Rapid City

5h 57m1 stop Minneapolis St Paul

$295Delta

Tue, Nov 3 - Tue, Nov 10

7:05 am - 2:36 pmRAP Rapid City-TYS Knoxville McGhee Tyson

5h 31m1 stop Denver Intl

8:45 am - 2:43 pmTYS Knoxville McGhee Tyson-RAP Rapid City

7h 58m1 stop Denver Intl

$307United Airlines

Tue, Jan 5 - Tue, Jan 12

7:00 am - 3:00 pmRAP Rapid City-TYS Knoxville McGhee Tyson

6h 00m1 stop Denver Intl

5:05 pm - 10:30 pmTYS Knoxville McGhee Tyson-RAP Rapid City

7h 25m1 stop Denver Intl

$313United Airlines

Wed, Nov 4 - Mon, Nov 9

11:29 am - 10:02 pmRAP Rapid City-TYS Knoxville McGhee Tyson

8h 33m2 stops Minneapolis St Paul Atlanta Hartsfield-Jackson

6:40 pm - 10:37 pmTYS Knoxville McGhee Tyson-RAP Rapid City

5h 57m1 stop Minneapolis St Paul

$314Delta

Tue, Nov 3 - Tue, Nov 10

3:22 pm - 11:47 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

7h 25m1 stop Chicago O'Hare Intl

6:50 am - 12:28 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

6h 38m1 stop Dallas/Fort Worth

$319American Airlines

Fri, Dec 4 - Fri, Dec 11

4:09 pm - 11:02 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 53m1 stop Minneapolis St Paul

7:55 am - 12:11 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 16m1 stop Minneapolis St Paul

$332Delta

Tue, Dec 29 - Tue, Jan 5

6:24 am - 12:51 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 27m1 stop Chicago O'Hare Intl

6:03 am - 12:17 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 14m1 stop Dallas/Fort Worth

$334American Airlines

Wed, Aug 26 - Mon, Aug 31

7:31 pm - 1:11 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

16h 40m1 stop Denver Intl

4:50 pm - 6:44 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

26h 54m1 stop Orlando Sanford Intl

$344Multiple Airlines

Wed, Oct 21 - Sat, Oct 24

8:52 pm - 10:05 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

24h 13m2 stops Denver Intl Phoenix Sky Harbor Intl

6:41 pm - 6:06 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

24h 25m1 stop Orlando Sanford Intl

$379Multiple Airlines

Fri, Oct 2 - Wed, Oct 7

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United Airlines flights from South Dakota to Knoxville

Our best United Airlines deals on South Dakota to Knoxville flight tickets

United Airlines

Jan 5

RAP7:05 amRapid City

5h 31m

1 stop

TYS2:36 pmKnoxville McGhee Tyson

Jan 12

TYS10:50 amKnoxville McGhee Tyson

8h 13m

2 stops

RAP5:03 pmRapid City

$284

United Airlines

Jan 5

RAP7:05 amRapid City

5h 31m

1 stop

TYS2:36 pmKnoxville McGhee Tyson

Jan 12

TYS8:45 amKnoxville McGhee Tyson

7h 58m

1 stop

RAP2:43 pmRapid City

$307

United Airlines

Nov 4

RAP7:00 amRapid City

6h 00m

1 stop

TYS3:00 pmKnoxville McGhee Tyson

Nov 9

TYS5:05 pmKnoxville McGhee Tyson

7h 25m

1 stop

RAP10:30 pmRapid City

$313

Delta flights from South Dakota to Knoxville

Our best Delta deals on South Dakota to Knoxville flight tickets

Delta

Nov 3

RAP11:29 amRapid City

8h 33m

2 stops

TYS10:02 pmKnoxville McGhee Tyson

Nov 10

TYS6:40 pmKnoxville McGhee Tyson

5h 57m

1 stop

RAP10:37 pmRapid City

$295

Delta

Nov 3

RAP11:29 amRapid City

8h 33m

2 stops

TYS10:02 pmKnoxville McGhee Tyson

Nov 10

TYS6:40 pmKnoxville McGhee Tyson

5h 57m

1 stop

RAP10:37 pmRapid City

$314

Delta

Dec 29

FSD4:09 pmSioux Falls Joe Foss Field

5h 53m

1 stop

TYS11:02 pmKnoxville McGhee Tyson

Jan 5

TYS7:55 amKnoxville McGhee Tyson

5h 16m

1 stop

FSD12:11 pmSioux Falls Joe Foss Field

$332

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Rapid CityKnoxville

RAP Rapid City - TYS Knoxville McGhee Tyson

RAPTYS

Rapid City

Tue 1/5

7:05 am-2:36 pm

1 stop5h 31m

Knoxville McGhee Tyson

Tue 1/12

10:50 am-5:03 pm

2 stops8h 13m

$284

Rapid CityKnoxville

RAP Rapid City - TYS Knoxville McGhee Tyson

RAPTYS

Rapid City

Tue 11/3

11:29 am-10:02 pm

2 stops8h 33m

Knoxville McGhee Tyson

Tue 11/10

6:40 pm-10:37 pm

1 stop5h 57m

$295

Rapid CityKnoxville

RAP Rapid City - TYS Knoxville McGhee Tyson

RAPTYS

Rapid City

Tue 1/5

7:05 am-2:36 pm

1 stop5h 31m

Knoxville McGhee Tyson

Tue 1/12

8:45 am-2:43 pm

1 stop7h 58m

$307

Rapid CityKnoxville

RAP Rapid City - TYS Knoxville McGhee Tyson

RAPTYS

Rapid City

Wed 11/4

7:00 am-3:00 pm

1 stop6h 00m

Knoxville McGhee Tyson

Mon 11/9

5:05 pm-10:30 pm

1 stop7h 25m

$313

Rapid CityKnoxville

RAP Rapid City - TYS Knoxville McGhee Tyson

RAPTYS

Rapid City

Tue 11/3

11:29 am-10:02 pm

2 stops8h 33m

Knoxville McGhee Tyson

Tue 11/10

6:40 pm-10:37 pm

1 stop5h 57m

$314

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Fri 12/4

3:22 pm-11:47 pm

1 stop7h 25m

Knoxville McGhee Tyson

Fri 12/11

6:50 am-12:28 pm

1 stop6h 38m

$319

Quickest round-trip

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Tue 12/29

4:09 pm-11:02 pm

1 stop5h 53m

Knoxville McGhee Tyson

Tue 1/5

7:55 am-12:11 pm

1 stop5h 16m

$332

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Wed 8/26

6:24 am-12:51 pm

1 stop5h 27m

Knoxville McGhee Tyson

Mon 8/31

6:03 am-12:17 pm

1 stop7h 14m

$334

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Wed 10/21

7:31 pm-1:11 pm

1 stop16h 40m

Knoxville McGhee Tyson

Sat 10/24

4:50 pm-6:44 pm

1 stop26h 54m

$344

Sioux FallsKnoxville

FSD Sioux Falls Joe Foss Field - TYS Knoxville McGhee Tyson

FSDTYS

Sioux Falls Joe Foss Field

Fri 10/2

8:52 pm-10:05 pm

2 stops24h 13m

Knoxville McGhee Tyson

Wed 10/7

6:41 pm-6:06 pm

1 stop24h 25m

$379

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Dakota to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Knoxville?

The month of October is, on average, the cheapest month to fly to Knoxville from South Dakota, with most prices found around $277. If you aren’t able to travel during the month of October, then book flights to Knoxville from South Dakota during April instead. Flights to Knoxville in April, while not as cheap as those in October, still average around $289.

Can stopping save me money on South Dakota to Knoxville flights?

You could potentially save up to 11% on your flight if you consider stops on a South Dakota to Knoxville flight.

Cheap South Dakota to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Dakota to Knoxville

Fastest flight time	4h 41m
Direct flights	None

The fastest flight from South Dakota to Knoxville takes 4h 41m

There are no direct flights from South Dakota to Knoxville. There are no popular flight routes from South Dakota to Knoxville.

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Frequently asked questions about flying from South Dakota to Knoxville

When did momondo last update prices for flights from South Dakota to Knoxville McGhee Tyson Airport?
Prices for flights from South Dakota to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from South Dakota to Knoxville McGhee Tyson Airport?
There are 3 operators available for flights from South Dakota to Knoxville McGhee Tyson Airport as of August 2026.
How old do you have to be to fly from South Dakota to Knoxville McGhee Tyson Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Dakota to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Dakota to Knoxville

Compare and see reviews for airlines that fly from South Dakota to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $248	Free Cancellation	Rating 7.1 11,911 reviews	Search American Airlines flights
Delta	PriceFrom $274	Free Cancellation	Rating 7.8 8,505 reviews	Search Delta flights
United Airlines	PriceFrom $277	Free Cancellation	Rating 7.4 10,111 reviews	Search United Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Alcoa

Maryville

Crossville

Murphy

Oak Ridge

Kodak

Newport

Dandridge

Lenoir City

Clinton

Jefferson City

Rockford

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Can I find flights from South Dakota to Knoxville with flexible booking policies on momondo?

Flights from South Dakota to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from South Dakota to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from South Dakota. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Dakota to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from South Dakota are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from South Dakota to Knoxville from $284

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Dakota to Knoxville departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from South Dakota to Knoxville

What is the cheapest month to fly to Knoxville?

Can stopping save me money on South Dakota to Knoxville flights?

What is the cheapest airline that flies from South Dakota to Knoxville McGhee Tyson?

What airlines fly to Knoxville?

How many flights depart from South Dakota to Knoxville on average per week?

How long does it take to fly to Knoxville?

Cheap South Dakota to Knoxville flight deals and tips

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Frequently asked questions about flying from South Dakota to Knoxville

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Why use momondo?

An easier way to manage your Knoxville trip

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