What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from South Carolina according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 4 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

How long is the flight from South Carolina to South America?

Average flight duration from South Carolina to South America depends on which airport you fly into and out of. Flying from Greenville to Copenhagen is 15h 16m on average, while flying from Charleston to Copenhagen is 18h 35m on average. Copenhagen is the most popular airport in South America.

What is the cheapest airline that flies from South Carolina to South America?

Spirit Airlines, LATAM Airlines, and American Airlines are the most popular carriers operating from South Carolina to South America

When did momondo last update prices for flights from South Carolina to South America?

Prices for flights from South Carolina to South America are updated daily.

How many operators does momondo search for flights from South Carolina to South America?

As of March 2026, there are 6 operators available to choose from for flights from South Carolina to South America.

How old do you have to be to fly from South Carolina to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$109 Cheap Flights from South Carolina to South America in 2026

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Find the cheapest flights from South Carolina to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:06 pm

CLT

CTG

7h 06m

1 stop

1:11 pm - 8:49 pm

CTG

CLT

6h 38m

1 stop

$242Spirit Airlines

ש', אפר' 11 - ד', אפר' 15

9:00 pm - 12:06 pm

CLT

CTG

16h 06m

1 stop

1:11 pm - 8:49 pm

CTG

CLT

6h 38m

1 stop

$273Spirit Airlines

ב', אפר' 13 - א', אפר' 19

6:00 am - 1:19 pm

CLT

CLO

8h 19m

1 stop

2:24 pm - 8:21 am

CLO

CLT

16h 57m

1 stop

$276Spirit Airlines

ד', אפר' 8 - ב', אפר' 13

3:08 pm - 5:00 am

CLT

LIM

14h 52m

1 stop

12:15 am - 1:38 pm

LIM

CLT

12h 23m

1 stop

$400Multiple Airlines

ה', אפר' 9 - ד', אפר' 15

3:08 pm - 5:00 am

CLT

LIM

14h 52m

1 stop

12:15 am - 8:05 am

LIM

CLT

30h 50m

2 stops

$424Multiple Airlines

ה', אפר' 9 - ד', אפר' 22

6:00 am - 4:25 am

GSP

BOG

23h 25m

2 stops

12:14 am - 10:14 am

BOG

GSP

33h 00m

2 stops

$504United Airlines

ד', מאי 27 - ב', יוני 29

7:49 pm - 4:25 am

GSP

BOG

9h 36m

1 stop

12:14 am - 9:17 pm

BOG

GSP

20h 03m

2 stops

$505United Airlines

ד', מאי 27 - ב', יוני 29

2:25 pm - 12:05 pm

GSP

BOG

22h 40m

2 stops

2:55 pm - 9:27 am

BOG

GSP

17h 32m

1 stop

$515Delta

ד', יולי 29 - ד', ספט' 9

2:38 pm - 5:20 pm

CLT

GIG

25h 42m

2 stops

6:05 am - 11:52 pm

GIG

CLT

18h 47m

2 stops

$657GOL

ג', אוג' 25 - א', אוג' 30

6:50 pm - 12:50 pm

CLT

GIG

17h 00m

2 stops

6:05 am - 9:43 pm

GIG

CLT

16h 38m

2 stops

$660GOL

ד', אוג' 26 - ג', ספט' 8

American Airlines flights from South Carolina to South America

Our best American Airlines deals on South Carolina to South America flight tickets

American Airlines

Apr 9

GSP5:20 amGreenville

8h 45m

2 stops

BOG1:05 pmBogotá El Dorado

Apr 21

BOG6:30 amBogotá El Dorado

13h 43m

2 stops

GSP9:13 pmGreenville

$542

American Airlines

Aug 17

CLT5:17 amCharlotte Douglas

19h 38m

1 stop

UIO11:55 pmQuito Mariscal Sucr

Aug 31

UIO11:40 pmQuito Mariscal Sucr

13h 16m

1 stop

CLT1:56 pmCharlotte Douglas

$545

American Airlines

Mar 30

GSP6:40 amGreenville

7h 00m

1 stop

BOG12:40 pmBogotá El Dorado

Apr 6

BOG1:40 pmBogotá El Dorado

9h 41m

1 stop

GSP12:21 amGreenville

$549

Spirit Airlines flights from South Carolina to South America

Our best Spirit Airlines deals on South Carolina to South America flight tickets

Spirit Airlines

Apr 11

CLT6:00 amCharlotte Douglas

7h 06m

1 stop

CTG12:06 pmCartagena Rafael Nunez

Apr 15

CTG1:11 pmCartagena Rafael Nunez

6h 38m

1 stop

CLT8:49 pmCharlotte Douglas

$242

Spirit Airlines

Apr 13

CLT9:00 pmCharlotte Douglas

16h 06m

1 stop

CTG12:06 pmCartagena Rafael Nunez

Apr 19

CTG1:11 pmCartagena Rafael Nunez

6h 38m

1 stop

CLT8:49 pmCharlotte Douglas

$273

Spirit Airlines

Apr 8

CLT6:00 amCharlotte Douglas

8h 19m

1 stop

CLO1:19 pmCali Alfonso B. Aragon Intl

Apr 13

CLO2:24 pmCali Alfonso B. Aragon Intl

16h 57m

1 stop

CLT8:21 amCharlotte Douglas

$276

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

ש' 4/11

6:00 am-12:06 pm

1 stop7h 06m

Cartagena Rafael Nunez

ד' 4/15

1:11 pm-8:49 pm

1 stop6h 38m

$242

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

ב' 4/13

9:00 pm-12:06 pm

1 stop16h 06m

Cartagena Rafael Nunez

א' 4/19

1:11 pm-8:49 pm

1 stop6h 38m

$273

CharlotteCali

CLT - CLO

CLTCLO

Charlotte Douglas

ד' 4/8

6:00 am-1:19 pm

1 stop8h 19m

Cali Alfonso B. Aragon Intl

ב' 4/13

2:24 pm-8:21 am

1 stop16h 57m

$276

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

ה' 4/9

3:08 pm-5:00 am

1 stop14h 52m

Lima J Chavez Intl

ד' 4/15

12:15 am-1:38 pm

1 stop12h 23m

$400

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

ה' 4/9

3:08 pm-5:00 am

1 stop14h 52m

Lima J Chavez Intl

ד' 4/22

12:15 am-8:05 am

2 stops30h 50m

$424

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

ד' 5/27

6:00 am-4:25 am

2 stops23h 25m

Bogotá El Dorado

ב' 6/29

12:14 am-10:14 am

2 stops33h 00m

$504

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

ד' 5/27

7:49 pm-4:25 am

1 stop9h 36m

Bogotá El Dorado

ב' 6/29

12:14 am-9:17 pm

2 stops20h 03m

$505

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

ד' 7/29

2:25 pm-12:05 pm

2 stops22h 40m

Bogotá El Dorado

ד' 9/9

2:55 pm-9:27 am

1 stop17h 32m

$515

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

ג' 8/25

2:38 pm-5:20 pm

2 stops25h 42m

Rio de Janeiro–Galeão Intl

א' 8/30

6:05 am-11:52 pm

2 stops18h 47m

$657

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

ד' 8/26

6:50 pm-12:50 pm

2 stops17h 00m

Rio de Janeiro–Galeão Intl

ג' 9/8

6:05 am-9:43 pm

2 stops16h 38m

$660

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from South Carolina to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $535. If you aren’t able to travel during the month of April, then book flights to South America from South Carolina during September instead. Flights to South America in September, while not as cheap as those in April, still average around $633.

Can stopping save me money on South Carolina to South America flights?

You could potentially save up to 31% on your flight if you consider stops on a South Carolina to South America flight.

Cheap South Carolina to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to South America

Fastest flight time	4h 59m
Direct flights	None

The fastest flight from South Carolina to South America takes 4h 59m

There are no direct flights from South Carolina to South America. There are no popular flight routes from South Carolina to South America.

Search flight deals

When did momondo last update prices for flights from South Carolina to South America?
Prices for flights from South Carolina to South America are updated daily.
How many operators does momondo search for flights from South Carolina to South America?
As of March 2026, there are 6 operators available to choose from for flights from South Carolina to South America.
How old do you have to be to fly from South Carolina to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to South America

Compare and see reviews for airlines that fly from South Carolina to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $301	Free Cancellation	Rating 7.9 8,238 reviews	Search Delta flights
Spirit Airlines	PriceFrom $327	Free Cancellation	Rating 6.3 8,486 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $458	Free Cancellation	Rating 7.1 11,371 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $494	Free Cancellation	Rating 7.4 1,919 reviews	Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to South America?

Finding the right flight to South America from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from South Carolina to South America with flexible booking policies on momondo?

Yes. All flights to South America from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to South America?

Once all potential South Carolina to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.