What airlines fly to South America?

American Airlines, LATAM Airlines and Delta are the top three most popular airlines that fly to South America from South Carolina according to our data. American Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to South America?

Spirit Airlines, Avianca, and United Airlines are the most popular carriers operating from South Carolina to South America

How long is the flight from South Carolina to South America?

Average flight duration from South Carolina to South America depends on which airport you fly into and out of. Flying from Myrtle Beach to Copenhagen is 13h 51m on average, while flying from Charleston to Copenhagen is 16h 08m on average. Copenhagen is the most popular airport in South America.

When did momondo last update prices for flights from South Carolina to South America?

Prices for flights from South Carolina to South America are updated daily.

How many operators does momondo search for flights from South Carolina to South America?

As of April 2026, there are 6 operators available to choose from for flights from South Carolina to South America.

How old do you have to be to fly from South Carolina to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$131 Cheap Flights from South Carolina to South America in 2026

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Find the cheapest flights from South Carolina to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:07 pm - 12:26 pm

CLT

CTG

16h 19m

1 stop

1:31 pm - 11:40 pm

CTG

CLT

9h 09m

1 stop

$224Spirit Airlines

Sun, May 17 - Wed, May 20

6:00 am - 12:26 pm

CLT

CTG

7h 26m

1 stop

1:31 pm - 11:40 pm

CTG

CLT

9h 09m

1 stop

$234Spirit Airlines

Mon, May 18 - Wed, May 27

6:00 am - 12:26 pm

CLT

CTG

7h 26m

1 stop

1:31 pm - 11:40 pm

CTG

CLT

9h 09m

1 stop

$248Spirit Airlines

Mon, May 18 - Wed, May 27

5:50 pm - 12:26 pm

CLT

CTG

19h 36m

1 stop

1:31 pm - 11:40 pm

CTG

CLT

9h 09m

1 stop

$270Multiple Airlines

Sat, May 9 - Wed, May 13

3:16 pm - 12:26 pm

CLT

CTG

22h 10m

1 stop

1:31 pm - 12:05 pm

CTG

CLT

21h 34m

1 stop

$291Multiple Airlines

Wed, May 27 - Sun, May 31

6:00 am - 8:16 pm

CHS

MDE

15h 16m

1 stop

6:00 am - 7:31 pm

MDE

CHS

12h 31m

1 stop

$577American Airlines

Sun, Jul 19 - Sat, Aug 1

2:07 pm - 11:51 pm

CHS

MDE

10h 44m

2 stops

5:50 am - 10:03 pm

MDE

CHS

15h 13m

2 stops

$582American Airlines

Wed, Sep 2 - Wed, Sep 9

8:12 pm - 2:02 pm

CHS

MDE

18h 50m

1 stop

1:25 pm - 7:17 pm

MDE

CHS

28h 52m

1 stop

$597JetBlue

Thu, May 7 - Tue, May 19

2:57 pm - 7:50 am

CLT

GIG

15h 53m

2 stops

6:05 am - 9:31 pm

GIG

CLT

16h 26m

2 stops

$651GOL

Mon, Jun 8 - Mon, Jun 15

2:57 pm - 10:40 am

CLT

GIG

18h 43m

2 stops

6:05 am - 9:54 pm

GIG

CLT

16h 49m

2 stops

$660GOL

Mon, Jun 15 - Sat, Jun 20

Spirit Airlines flights from South Carolina to South America

Our best Spirit Airlines deals on South Carolina to South America flight tickets

Spirit Airlines

May 17

CLT9:07 pmCharlotte Douglas

16h 19m

1 stop

CTG12:26 pmCartagena Rafael Nunez

May 20

CTG1:31 pmCartagena Rafael Nunez

9h 09m

1 stop

CLT11:40 pmCharlotte Douglas

$224

Spirit Airlines

May 18

CLT6:00 amCharlotte Douglas

7h 26m

1 stop

CTG12:26 pmCartagena Rafael Nunez

May 27

CTG1:31 pmCartagena Rafael Nunez

9h 09m

1 stop

CLT11:40 pmCharlotte Douglas

$234

Spirit Airlines

May 18

CLT6:00 amCharlotte Douglas

7h 26m

1 stop

CTG12:26 pmCartagena Rafael Nunez

May 27

CTG1:31 pmCartagena Rafael Nunez

9h 09m

1 stop

CLT11:40 pmCharlotte Douglas

$248

LATAM Airlines flights from South Carolina to South America

Our best LATAM Airlines deals on South Carolina to South America flight tickets

LATAM Airlines

May 29

CHS10:43 amCharleston

14h 02m

2 stops

MDE11:45 pmMedellín Jose Maria Cordova Intl

Jun 2

MDE8:25 amMedellín Jose Maria Cordova Intl

14h 34m

2 stops

CHS11:59 pmCharleston

$745

LATAM Airlines

May 5

CLT12:49 pmCharlotte Douglas

10h 06m

1 stop

LIM9:55 pmLima J Chavez Intl

May 12

LIM12:05 pmLima J Chavez Intl

10h 48m

1 stop

CLT11:53 pmCharlotte Douglas

$840

LATAM Airlines

May 7

CLT4:46 pmCharlotte Douglas

13h 14m

2 stops

LIM5:00 amLima J Chavez Intl

May 14

LIM12:05 pmLima J Chavez Intl

19h 51m

1 stop

CLT8:56 amCharlotte Douglas

$864

momondo Fare Finder

Use the filters below to find and compare flights from South Carolina to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sun 5/17

9:07 pm-12:26 pm

1 stop16h 19m

Cartagena Rafael Nunez

Wed 5/20

1:31 pm-11:40 pm

1 stop9h 09m

$224

Quickest round-trip

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Mon 5/18

6:00 am-12:26 pm

1 stop7h 26m

Cartagena Rafael Nunez

Wed 5/27

1:31 pm-11:40 pm

1 stop9h 09m

$234

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Mon 5/18

6:00 am-12:26 pm

1 stop7h 26m

Cartagena Rafael Nunez

Wed 5/27

1:31 pm-11:40 pm

1 stop9h 09m

$248

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sat 5/9

5:50 pm-12:26 pm

1 stop19h 36m

Cartagena Rafael Nunez

Wed 5/13

1:31 pm-11:40 pm

1 stop9h 09m

$270

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Wed 5/27

3:16 pm-12:26 pm

1 stop22h 10m

Cartagena Rafael Nunez

Sun 5/31

1:31 pm-12:05 pm

1 stop21h 34m

$291

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sun 7/19

6:00 am-8:16 pm

1 stop15h 16m

Medellín Jose Maria Cordova Intl

Sat 8/1

6:00 am-7:31 pm

1 stop12h 31m

$577

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 9/2

2:07 pm-11:51 pm

2 stops10h 44m

Medellín Jose Maria Cordova Intl

Wed 9/9

5:50 am-10:03 pm

2 stops15h 13m

$582

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Thu 5/7

8:12 pm-2:02 pm

1 stop18h 50m

Medellín Jose Maria Cordova Intl

Tue 5/19

1:25 pm-7:17 pm

1 stop28h 52m

$597

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Mon 6/8

2:57 pm-7:50 am

2 stops15h 53m

Rio de Janeiro–Galeão Intl

Mon 6/15

6:05 am-9:31 pm

2 stops16h 26m

$651

CharlotteRio de Janeiro

CLT - GIG

CLTGIG

Charlotte Douglas

Mon 6/15

2:57 pm-10:40 am

2 stops18h 43m

Rio de Janeiro–Galeão Intl

Sat 6/20

6:05 am-9:54 pm

2 stops16h 49m

$660

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South America?

In general, October is the cheapest month to fly from South Carolina to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $650. If you aren’t able to travel during the month of October, then book flights to South America from South Carolina during March instead. Flights to South America in March, while not as cheap as those in October, still average around $701.

Can stopping save me money on South Carolina to South America flights?

You could potentially save up to 26% on your flight if you consider stops on a South Carolina to South America flight.

Cheap South Carolina to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to South America

Fastest flight time	6h 55m
Direct flights	None

The fastest flight from South Carolina to South America takes 6h 55m

There are no direct flights from South Carolina to South America. There are no popular flight routes from South Carolina to South America.

Search flight deals

Frequently asked questions about flying from South Carolina to South America

When did momondo last update prices for flights from South Carolina to South America?
Prices for flights from South Carolina to South America are updated daily.
How many operators does momondo search for flights from South Carolina to South America?
As of April 2026, there are 6 operators available to choose from for flights from South Carolina to South America.
How old do you have to be to fly from South Carolina to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to South America

Compare and see reviews for airlines that fly from South Carolina to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $301	Free Cancellation	Rating 7.9 8,437 reviews	Search Delta flights
American Airlines	PriceFrom $493	Free Cancellation	Rating 7.1 11,655 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $535	Free Cancellation	Rating 7.4 1,912 reviews	Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to South America?

Finding the right flight to South America from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from South Carolina to South America with flexible booking policies on momondo?

Yes. All flights to South America from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to South America?

Once all potential South Carolina to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.