Cheap flights from South Carolina to South America from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to South America departing on 8/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Spirit Airlines Logo
6:00 am - 1:10 pmCLT-BOG
8h 10m1 stop
Spirit Airlines Logo
2:05 pm - 9:22 amBOG-CLT
18h 17m1 stop
$264Spirit Airlines
Find Deal
Wed, Sep 17 - Sun, Sep 21
Spirit Airlines Logo
7:00 am - 11:54 pmCLT-MDE
17h 54m1 stop
Spirit Airlines Logo
2:20 pm - 11:55 pmMDE-CLT
8h 35m1 stop
$264Spirit Airlines
Find Deal
Mon, Aug 25 - Thu, Aug 28
 Logo
5:45 am - 9:57 pmCLT-MDE
17h 12m2 stops
 Logo
2:09 pm - 10:59 pmMDE-CLT
7h 50m1 stop
Tue, Sep 23 - Thu, Sep 25
 Logo
2:50 pm - 1:04 pmGSP-MDE
23h 14m1 stop
 Logo
2:00 pm - 8:48 amMDE-GSP
17h 48m1 stop
Fri, Aug 15 - Thu, Aug 21
United Airlines Logo
7:00 am - 1:46 pmCLT-GYE
31h 46m2 stops
United Airlines Logo
2:44 pm - 9:59 pmGYE-CLT
30h 15m2 stops
$497United Airlines
Find Deal
Wed, Sep 24 - Tue, Oct 14
American Airlines Logo
6:00 am - 8:15 pmGSP-MDE
15h 15m1 stop
American Airlines Logo
1:35 pm - 11:21 pmMDE-GSP
8h 46m1 stop
$506American Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
American Airlines Logo
5:00 am - 8:15 pmGSP-MDE
16h 15m2 stops
American Airlines Logo
6:00 am - 9:47 pmMDE-GSP
14h 47m2 stops
$510American Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
United Airlines Logo
6:45 am - 11:16 amCLT-GYE
29h 31m2 stops
United Airlines Logo
8:30 am - 9:59 pmGYE-CLT
37h 29m2 stops
$516United Airlines
Find Deal
Tue, Oct 28 - Fri, Nov 21
LATAM Airlines Logo
2:20 pm - 6:25 amCLT-LIM
16h 05m2 stops
LATAM Airlines Logo
12:15 am - 1:08 pmLIM-CLT
12h 53m2 stops
$614LATAM Airlines
Find Deal
Tue, Nov 25 - Fri, Dec 12
LATAM Airlines Logo
4:30 pm - 6:25 amCLT-LIM
13h 55m2 stops
LATAM Airlines Logo
12:00 pm - 8:40 amLIM-CLT
20h 40m2 stops
$617LATAM Airlines
Find Deal
Sun, Jan 25 - Sun, Feb 8

Spirit Airlines flights from South Carolina to South America

Our best Spirit Airlines deals on South Carolina to South America flight tickets
Spirit Airlines
Sep 17
CLT6:00 amCharlotte Douglas
8h 10m
1 stop
BOG1:10 pmBogotá El Dorado
Sep 21
BOG2:05 pmBogotá El Dorado
18h 17m
1 stop
CLT9:22 amCharlotte Douglas
Spirit Airlines
Sep 12
CLT3:34 pmCharlotte Douglas
9h 51m
1 stop
MDE12:25 amMedellín Jose Maria Cordova Intl
Sep 19
MDE2:09 pmMedellín Jose Maria Cordova Intl
18h 13m
1 stop
CLT9:22 amCharlotte Douglas
Spirit Airlines
Sep 22
CLT5:45 amCharlotte Douglas
8h 25m
1 stop
BOG1:10 pmBogotá El Dorado
Sep 28
BOG2:05 pmBogotá El Dorado
18h 17m
1 stop
CLT9:22 amCharlotte Douglas

LATAM Airlines flights from South Carolina to South America

Our best LATAM Airlines deals on South Carolina to South America flight tickets
LATAM Airlines
Nov 25
CLT2:20 pmCharlotte Douglas
16h 05m
2 stops
LIM6:25 amLima J Chavez Intl
Dec 12
LIM12:15 amLima J Chavez Intl
12h 53m
2 stops
CLT1:08 pmCharlotte Douglas
LATAM Airlines
Aug 16
GSP7:48 amGreenville
15h 41m
2 stops
MDE10:29 pmMedellín Jose Maria Cordova Intl
Aug 23
MDE4:26 amMedellín Jose Maria Cordova Intl
16h 58m
2 stops
GSP10:24 pmGreenville
LATAM Airlines
Jan 25
CLT4:30 pmCharlotte Douglas
13h 55m
2 stops
LIM6:25 amLima J Chavez Intl
Feb 8
LIM12:00 pmLima J Chavez Intl
20h 40m
2 stops
CLT8:40 amCharlotte Douglas

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from South Carolina to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 9/17

6:00 am-1:10 pm

1 stop8h 10m

Bogotá El Dorado

Sun 9/21

2:05 pm-9:22 am

1 stop18h 17m

$264

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 8/25

7:00 am-11:54 pm

1 stop17h 54m

Medellín Jose Maria Cordova Intl

Thu 8/28

2:20 pm-11:55 pm

1 stop8h 35m

$264

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 9/23

5:45 am-9:57 pm

2 stops17h 12m

Medellín Jose Maria Cordova Intl

Thu 9/25

2:09 pm-10:59 pm

1 stop7h 50m

$330

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 8/15

2:50 pm-1:04 pm

1 stop23h 14m

Medellín Jose Maria Cordova Intl

Thu 8/21

2:00 pm-8:48 am

1 stop17h 48m

$371

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 9/24

7:00 am-1:46 pm

2 stops31h 46m

Guayaquil Jose Joaquin de Olmedo

Tue 10/14

2:44 pm-9:59 pm

2 stops30h 15m

$497

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

6:00 am-8:15 pm

1 stop15h 15m

Medellín Jose Maria Cordova Intl

Tue 10/28

1:35 pm-11:21 pm

1 stop8h 46m

$506

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

5:00 am-8:15 pm

2 stops16h 15m

Medellín Jose Maria Cordova Intl

Tue 10/28

6:00 am-9:47 pm

2 stops14h 47m

$510

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 10/28

6:45 am-11:16 am

2 stops29h 31m

Guayaquil Jose Joaquin de Olmedo

Fri 11/21

8:30 am-9:59 pm

2 stops37h 29m

$516

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

Tue 11/25

2:20 pm-6:25 am

2 stops16h 05m

Lima J Chavez Intl

Fri 12/12

12:15 am-1:08 pm

2 stops12h 53m

$614

CharlotteLima

CLT - LIM

CLTLIM

Charlotte Douglas

Sun 1/25

4:30 pm-6:25 am

2 stops13h 55m

Lima J Chavez Intl

Sun 2/8

12:00 pm-8:40 am

2 stops20h 40m

$617

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from South Carolina to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $585. If you aren’t able to travel during the month of January, then book flights to South America from South Carolina during April instead. Flights to South America in April, while not as cheap as those in January, still average around $625.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from South Carolina to South America is on a Monday when prices can be found for as low as $530. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to South America for around $871.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest South Carolina to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $659. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $833 on average. Flights to South America from South Carolina in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on South Carolina to South America flights?

You could potentially save up to 57% on your flight if you consider stops on a South Carolina to South America flight.

Cheap South Carolina to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to South America

Best Price Found

$110

Fastest flight time

6h 20m

Direct flights

None

Airports in South America

3 airports
The best one-way flight to South America from South Carolina in the past 72 hours is $110. The best round-trip flight deal from South Carolina to South America found on momondo in the last 72 hours is $264.
The fastest flight from South Carolina to South America takes 6h 20m
There are no direct flights from South Carolina to South America. Popular non-direct routes for this connection are Charlotte Douglas Airport - Bogotá El Dorado Airport and Charlotte Douglas Airport - Medellín Jose Maria Cordova Intl Airport.
There are 3 airports near South America: Guayaquil Jose Joaquin de Olmedo (GYE), Bogotá El Dorado (BOG), Medellín Jose Maria Cordova Intl (MDE)

  • When did momondo last update prices for flights from South Carolina to South America?

    Prices for flights from South Carolina to South America are updated daily.

  • How many operators does momondo search for flights from South Carolina to South America?

  • How old do you have to be to fly from South Carolina to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.


Best airlines flying from South Carolina to South America

Compare and see reviews for airlines that fly from South Carolina to South America with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $333Free CancellationRating
6.3
8,058 reviews
Search Spirit Airlines flights
DeltaPriceFrom $436Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $458Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $502Free CancellationRating
7.5
1,823 reviews
Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to South America?

Finding the right flight to South America from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from South Carolina to South America with flexible booking policies on momondo?

Yes. All flights to South America from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to South America?

Once all potential South Carolina to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to South America right now. Can momondo alert me if prices change?

If you are not ready to book a flight from South Carolina to South America now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South America and let you know when they change.


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1 adult
Thu 8/7
Thu 8/14

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Popular flights according to clicks in the last 7 days on momondo