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Cheap flights from South Carolina to Chicago from $44

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 2/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
10:46 pm - 12:17 am
CLT
-
ORD
2h 31mnonstop
Frontier Logo
6:55 pm - 9:57 pm
ORD
-
CLT
2h 02mnonstop
$58Frontier
Fri, Mar 6 - Sun, Mar 8
Frontier Logo
8:20 pm - 9:42 pm
CLT
-
ORD
2h 22mnonstop
Frontier Logo
4:19 pm - 7:25 pm
ORD
-
CLT
2h 06mnonstop
$59Frontier
Thu, Feb 5 - Mon, Feb 9
Spirit Airlines Logo
5:05 pm - 10:42 pm
CHS
-
ORD
6h 37m
1 stop
Spirit Airlines Logo
7:00 am - 5:40 pm
ORD
-
CHS
9h 40m
1 stop
$102Spirit Airlines
Sat, Feb 7 - Sat, Feb 28
Spirit Airlines Logo
5:05 pm - 10:42 pm
CHS
-
ORD
6h 37m
1 stop
Spirit Airlines Logo
7:00 am - 5:40 pm
ORD
-
CHS
9h 40m
1 stop
$104Spirit Airlines
Sat, Feb 7 - Sat, Feb 28
Multiple Airlines Logo
7:00 am - 1:56 pm
CLT
-
MDW
7h 56m
1 stop
Multiple Airlines Logo
6:45 am - 6:13 pm
MDW
-
CLT
10h 28m
1 stop
$138Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
$139Southwest
Wed, Feb 11 - Wed, Feb 18
Multiple Airlines Logo
6:35 pm - 11:03 pm
CHS
-
ORD
29h 28m
1 stop
Multiple Airlines Logo
12:05 pm - 4:05 pm
ORD
-
CHS
27h 00m
1 stop
$139Multiple Airlines
Thu, Feb 19 - Thu, Feb 26
Southwest Logo
6:25 pm - 7:30 pm
CLT
-
MDW
2h 05mnonstop
Southwest Logo
6:00 pm - 8:50 pm
MDW
-
CLT
1h 50mnonstop
$158Southwest
Sat, Feb 14 - Sun, Feb 15
JetBlue Logo
5:21 pm - 10:59 pm
SAV
-
ORD
6h 38m
1 stop
JetBlue Logo
6:04 am - 4:22 pm
ORD
-
SAV
9h 18m
1 stop
$173JetBlue
Thu, Feb 26 - Sat, Feb 28
JetBlue Logo
5:25 pm - 10:59 pm
SAV
-
ORD
6h 34m
1 stop
JetBlue Logo
6:04 am - 4:25 pm
ORD
-
SAV
9h 21m
1 stop
$189JetBlue
Mon, Mar 2 - Mon, Mar 9

Frontier flights from South Carolina to Chicago

Our best Frontier deals on South Carolina to Chicago flight tickets
Frontier
Mar 6
CLT10:46 pmCharlotte Douglas
2h 31m
ORD12:17 amChicago O'Hare Intl
Mar 8
ORD6:55 pmChicago O'Hare Intl
2h 02m
CLT9:57 pmCharlotte Douglas
$58
Frontier
Feb 5
CLT8:20 pmCharlotte Douglas
2h 22m
ORD9:42 pmChicago O'Hare Intl
Feb 9
ORD4:19 pmChicago O'Hare Intl
2h 06m
CLT7:25 pmCharlotte Douglas
$59
Frontier
Feb 5
CLT8:20 pmCharlotte Douglas
2h 22m
ORD9:42 pmChicago O'Hare Intl
Feb 9
ORD4:19 pmChicago O'Hare Intl
2h 06m
CLT7:25 pmCharlotte Douglas
$60

Spirit Airlines flights from South Carolina to Chicago

Our best Spirit Airlines deals on South Carolina to Chicago flight tickets
Spirit Airlines
Feb 7
CHS5:05 pmCharleston
6h 37m
1 stop
ORD10:42 pmChicago O'Hare Intl
Feb 28
ORD7:00 amChicago O'Hare Intl
9h 40m
1 stop
CHS5:40 pmCharleston
$102
Spirit Airlines
Feb 18
CHS5:00 pmCharleston
8h 40m
1 stop
ORD12:40 amChicago O'Hare Intl
Feb 23
ORD5:15 amChicago O'Hare Intl
11h 25m
1 stop
CHS5:40 pmCharleston
$115
Spirit Airlines
Feb 11
CLT6:00 amCharlotte Douglas
6h 22m
1 stop
ORD11:22 amChicago O'Hare Intl
Feb 18
ORD4:43 pmChicago O'Hare Intl
6h 13m
1 stop
CLT11:56 pmCharlotte Douglas
$118

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 3/6

10:46 pm-12:17 am

Nonstop2h 31m

Chicago O'Hare Intl

Sun 3/8

6:55 pm-9:57 pm

Nonstop2h 02m

$58

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 2/5

8:20 pm-9:42 pm

Nonstop2h 22m

Chicago O'Hare Intl

Mon 2/9

4:19 pm-7:25 pm

Nonstop2h 06m

$59

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Sat 2/7

5:05 pm-10:42 pm

1 stop6h 37m

Chicago O'Hare Intl

Sat 2/28

7:00 am-5:40 pm

1 stop9h 40m

$102

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Sat 2/7

5:05 pm-10:42 pm

1 stop6h 37m

Chicago O'Hare Intl

Sat 2/28

7:00 am-5:40 pm

1 stop9h 40m

$104

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 2/19

7:00 am-1:56 pm

1 stop7h 56m

Chicago Midway

Mon 2/23

6:45 am-6:13 pm

1 stop10h 28m

$138

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 2/11

5:50 pm-6:55 pm

Nonstop2h 05m

Chicago Midway

Wed 2/18

1:30 pm-4:20 pm

Nonstop1h 50m

$139

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Thu 2/19

6:35 pm-11:03 pm

1 stop29h 28m

Chicago O'Hare Intl

Thu 2/26

12:05 pm-4:05 pm

1 stop27h 00m

$139

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 2/14

6:25 pm-7:30 pm

Nonstop2h 05m

Chicago Midway

Sun 2/15

6:00 pm-8:50 pm

Nonstop1h 50m

$158

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Thu 2/26

5:21 pm-10:59 pm

1 stop6h 38m

Chicago O'Hare Intl

Sat 2/28

6:04 am-4:22 pm

1 stop9h 18m

$173

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Mon 3/2

5:25 pm-10:59 pm

1 stop6h 34m

Chicago O'Hare Intl

Mon 3/9

6:04 am-4:25 pm

1 stop9h 21m

$189

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from South Carolina, with most prices found around $284. If you’re not able to fly to Chicago in August, then September is your next best option. Flight prices from South Carolina to Chicago during September average around $310.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $400. This is often the case because there is less demand to fly during this day of the week. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Chicago for around $646.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the evening. Flights from South Carolina to Chicago during this time can be as low as $379. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $541.

What is the cheapest South Carolina to Chicago flight route?

Fly from Charleston to Chicago O'Hare Intl for the best South Carolina - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $373 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from South Carolina for as low as $268 on momondo.

What cabin class options are available on South Carolina to Chicago flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago flights?

You could potentially save up to 23% on your flight if you consider stops on a South Carolina to Chicago flight.

Cheap South Carolina to Chicago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago

Best Price Found

$159

Fastest flight time

2h 00m

Direct flights

Every day

Airports in Chicago

3 airports
The best one-way flight to Chicago from South Carolina in the past 72 hours is $159. The best round-trip flight deal from South Carolina to Chicago found on momondo in the last 72 hours is $333.
The fastest flight from South Carolina to Chicago takes 2h 00m
Direct flights go from South Carolina to Chicago every day.
There are 3 airports in Chicago. From South Carolina there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Chicago?

    Prices for flights from South Carolina to Chicago are updated daily.

  • How many operators does momondo search for flights from South Carolina to Chicago?

  • How old do you have to be to fly from South Carolina to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from South Carolina to Chicago?

Best airlines flying from South Carolina to Chicago

Compare and see reviews for airlines that fly from South Carolina to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $113Free CancellationRating
6.3
8,319 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $135Free CancellationRating
7.2
11,129 reviews
Search American Airlines flights
DeltaPriceFrom $180Free CancellationRating
7.9
8,048 reviews
Search Delta flights
SouthwestPriceFrom $190Free CancellationRating
8.0
4,258 reviews
Search Southwest flights
United AirlinesPriceFrom $193Free CancellationRating
7.4
9,163 reviews
Search United Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from South Carolina.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

All flight searches from South Carolina to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport