What is the cheapest airline that flies from South Carolina to Chicago?

Frontier, Southwest, and American Airlines are the most popular carriers operating from South Carolina to Chicago

How many flights depart from South Carolina to Chicago on average per week?

The number of flights available between South Carolina and Chicago is 731 per week as of September 2025. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.

What airlines fly to Chicago?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Chicago from South Carolina according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 5 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

How many flights depart from South Carolina to Chicago on average per day?

As of September 2025, 104 flights take off from South Carolina and land in Chicago each day. The most common flight departure time for this route is 11:00AM, with 51% of daily flights taking off at noon.

How long does it take to fly to Chicago?

Average flight duration from South Carolina to Chicago depends on which airport you fly into and out of. Flying from Greenville to Chicago O'Hare Intl Airport is 2h 02m on average, while flying from Columbia to Chicago O'Hare Intl Airport is 2h 16m on average. Chicago O'Hare Intl Airport is the most popular airport in Chicago.

When did momondo last update prices for flights from South Carolina to Chicago?

Prices for flights from South Carolina to Chicago are updated daily.

How many operators does momondo search for flights from South Carolina to Chicago?

The number of operators available for flights from South Carolina to Chicago is 7 as of September 2025.

How old do you have to be to fly from South Carolina to Chicago?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago.

What documentation or ID do you need to fly to Chicago?

The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$59 Cheap Flights from South Carolina to Chicago in 2025/26

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Find the cheapest flights from South Carolina to Chicago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

10:03 am - 11:18 amCLT-ORD

2h 15mnonstop

5:50 am - 9:00 amORD-CLT

2h 10mnonstop

$110Frontier

Find Deal

Fri, Oct 17 - Mon, Oct 20

10:03 am - 11:18 amCLT-ORD

2h 15mnonstop

6:00 am - 9:08 amORD-CLT

2h 08mnonstop

$111Frontier

Find Deal

Fri, Oct 17 - Sun, Oct 19

9:45 am - 11:14 amCLT-ORD

2h 29mnonstop

11:12 am - 9:39 pmORD-CLT

9h 27m1 stop

$130Multiple Airlines

Find Deal

Fri, Oct 24 - Sat, Oct 25

4:00 pm - 5:13 pmCLT-ORD

2h 13mnonstop

8:44 pm - 11:53 pmORD-CLT

2h 09mnonstop

$134American Airlines

Find Deal

Wed, Oct 29 - Wed, Oct 29

3:54 pm - 5:16 pmCLT-ORD

2h 22mnonstop

5:59 pm - 12:59 amORD-CLT

6h 00m1 stop

$135Multiple Airlines

Find Deal

Fri, Dec 5 - Tue, Dec 9

6:30 am - 7:50 amCLT-ORD

2h 20mnonstop

2:15 pm - 5:20 pmORD-CLT

2h 05mnonstop

$137United Airlines

Find Deal

Sat, Oct 25 - Sat, Nov 1

9:25 am - 10:32 amCLT-ORD

2h 07mnonstop

6:36 pm - 9:54 pmORD-CLT

2h 18mnonstop

$138American Airlines

Find Deal

Wed, Oct 29 - Sat, Nov 1

6:30 am - 7:50 amCLT-ORD

2h 20mnonstop

7:15 am - 10:32 amORD-CLT

2h 17mnonstop

$149United Airlines

Find Deal

Wed, Oct 22 - Wed, Oct 29

6:30 am - 7:25 amCLT-MDW

1h 55mnonstop

8:20 pm - 11:10 pmMDW-CLT

1h 50mnonstop

$150Southwest

Find Deal

Sat, Nov 1 - Sun, Nov 2

6:30 am - 7:25 amCLT-MDW

1h 55mnonstop

5:20 am - 11:15 amMDW-CLT

4h 55m1 stop

$160Southwest

Find Deal

Sat, Nov 1 - Sun, Nov 2

Spirit Airlines flights from South Carolina to Chicago

Our best Spirit Airlines deals on South Carolina to Chicago flight tickets

Spirit Airlines

Sep 29

CLT5:45 amCharlotte Douglas

12h 54m

1 stop

ORD5:39 pmChicago O'Hare Intl

Oct 6

ORD7:51 pmChicago O'Hare Intl

10h 56m

1 stop

CLT7:47 amCharlotte Douglas

$161

Find similar

Spirit Airlines

Sep 29

CLT5:45 amCharlotte Douglas

12h 54m

1 stop

ORD5:39 pmChicago O'Hare Intl

Oct 6

ORD7:51 pmChicago O'Hare Intl

10h 56m

1 stop

CLT7:47 amCharlotte Douglas

$162

Find similar

Spirit Airlines

Oct 8

MYR8:14 amMyrtle Beach Intl

9h 59m

1 stop

ORD5:13 pmChicago O'Hare Intl

Oct 11

ORD11:55 amChicago O'Hare Intl

7h 09m

1 stop

MYR8:04 pmMyrtle Beach Intl

$167

Find similar

Frontier flights from South Carolina to Chicago

Our best Frontier deals on South Carolina to Chicago flight tickets

Frontier

Oct 17

CLT10:03 amCharlotte Douglas

2h 15m

ORD11:18 amChicago O'Hare Intl

Oct 20

ORD5:50 amChicago O'Hare Intl

2h 10m

CLT9:00 amCharlotte Douglas

$110

Find similar

Frontier

Oct 17

CLT10:03 amCharlotte Douglas

2h 15m

ORD11:18 amChicago O'Hare Intl

Oct 19

ORD6:00 amChicago O'Hare Intl

2h 08m

CLT9:08 amCharlotte Douglas

$111

Find similar

Frontier

Oct 24

CLT9:42 amCharlotte Douglas

9h 33m

1 stop

ORD6:15 pmChicago O'Hare Intl

Oct 27

ORD5:50 amChicago O'Hare Intl

2h 10m

CLT9:00 amCharlotte Douglas

$112

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 10/17

10:03 am-11:18 am

Nonstop2h 15m

Chicago O'Hare Intl

Mon 10/20

5:50 am-9:00 am

Nonstop2h 10m

$110

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 10/17

10:03 am-11:18 am

Nonstop2h 15m

Chicago O'Hare Intl

Sun 10/19

6:00 am-9:08 am

Nonstop2h 08m

$111

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 10/24

9:45 am-11:14 am

Nonstop2h 29m

Chicago O'Hare Intl

Sat 10/25

11:12 am-9:39 pm

1 stop9h 27m

$130

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/29

4:00 pm-5:13 pm

Nonstop2h 13m

Chicago O'Hare Intl

Wed 10/29

8:44 pm-11:53 pm

Nonstop2h 09m

$134

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 12/5

3:54 pm-5:16 pm

Nonstop2h 22m

Chicago O'Hare Intl

Tue 12/9

5:59 pm-12:59 am

1 stop6h 00m

$135

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 10/25

6:30 am-7:50 am

Nonstop2h 20m

Chicago O'Hare Intl

Sat 11/1

2:15 pm-5:20 pm

Nonstop2h 05m

$137

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/29

9:25 am-10:32 am

Nonstop2h 07m

Chicago O'Hare Intl

Sat 11/1

6:36 pm-9:54 pm

Nonstop2h 18m

$138

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 10/22

6:30 am-7:50 am

Nonstop2h 20m

Chicago O'Hare Intl

Wed 10/29

7:15 am-10:32 am

Nonstop2h 17m

$149

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 11/1

6:30 am-7:25 am

Nonstop1h 55m

Chicago Midway

Sun 11/2

8:20 pm-11:10 pm

Nonstop1h 50m

$150

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 11/1

6:30 am-7:25 am

Nonstop1h 55m

Chicago Midway

Sun 11/2

5:20 am-11:15 am

1 stop4h 55m

$160

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How to get the cheapest flight ticket from South Carolina to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from South Carolina, with most prices found around $284. If you’re not able to fly to Chicago in August, then October is your next best option. Flight prices from South Carolina to Chicago during October average around $315.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $411. This is often the case because there is less demand to fly during this day of the week. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Chicago for around $584.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the evening. Flights from South Carolina to Chicago during this time can be as low as $369. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $507.

What is the cheapest South Carolina to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best South Carolina - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from South Carolina for as low as $262 on momondo.

What cabin class options are available on South Carolina to Chicago flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago flights?

You could potentially save up to 2% on your flight if you consider stops on a South Carolina to Chicago flight.

Cheap South Carolina to Chicago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago

Best Price Found	$144
Fastest flight time	1h 55m
Direct flights	Every day
Airports in Chicago	1 airport

The best one-way flight to Chicago from South Carolina in the past 72 hours is $144. The best round-trip flight deal from South Carolina to Chicago found on momondo in the last 72 hours is $289.

The fastest flight from South Carolina to Chicago takes 1h 55m

Direct flights go from South Carolina to Chicago every day.

There is 1 airport near Chicago: Chicago Midway (MDW)

Search flight deals

When did momondo last update prices for flights from South Carolina to Chicago?
Prices for flights from South Carolina to Chicago are updated daily.
How many operators does momondo search for flights from South Carolina to Chicago?
The number of operators available for flights from South Carolina to Chicago is 7 as of September 2025.
How old do you have to be to fly from South Carolina to Chicago?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago.
What documentation or ID do you need to fly to Chicago?
The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from South Carolina to Chicago?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from South Carolina to Chicago is Embraer 175 (Enhanced Winglets) (20.92% of total bookings). The next most popular plane models are Embraer 175 (15.87%), Embraer 170 (12.63%), and Canadair (Bombardier) Regional Jet CRJ-550 (9.28%).

Best airlines flying from South Carolina to Chicago

Compare and see reviews for airlines that fly from South Carolina to Chicago with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $47	Free Cancellation	Rating 6.3 8,051 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $139	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $180	Free Cancellation	Rating 7.9 7,973 reviews	Search Delta flights
Southwest	PriceFrom $190	Free Cancellation	Rating 8.0 4,245 reviews	Search Southwest flights
United Airlines	PriceFrom $193	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights

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Hammond

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Saint Joseph

Portage

Lansing

Schererville

Valparaiso

Crown Point

Munster

Chesterton

Monticello

Porter

Griffith

Saint John

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from South Carolina.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

All flight searches from South Carolina to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Chicago Midway Airport

Chicago O'Hare Intl Airport

Chicago Greater Rockford Airport

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Cheap flights from South Carolina to Chicago from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 11/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from South Carolina to Chicago

Cheap round-trip flights

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Cheap last minute flights

Cheap direct flights

Spirit Airlines flights from South Carolina to Chicago

Our best Spirit Airlines deals on South Carolina to Chicago flight tickets

Frontier flights from South Carolina to Chicago

Our best Frontier deals on South Carolina to Chicago flight tickets

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Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from South Carolina, with most prices found around $284. If you’re not able to fly to Chicago in August, then October is your next best option. Flight prices from South Carolina to Chicago during October average around $315.

What is the cheapest day to depart on your flight to Chicago?

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the evening. Flights from South Carolina to Chicago during this time can be as low as $369. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $507.

What is the cheapest South Carolina to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best South Carolina - Chicago flight prices

How far in advance should I book a flight to Chicago?

What cabin class options are available on South Carolina to Chicago flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago flights?

You could potentially save up to 2% on your flight if you consider stops on a South Carolina to Chicago flight.

What is the cheapest airline that flies from South Carolina to Chicago?

Frontier, Southwest, and American Airlines are the most popular carriers operating from South Carolina to Chicago

What airlines fly to Chicago?

How many flights depart from South Carolina to Chicago on average per day?

As of September 2025, 104 flights take off from South Carolina and land in Chicago each day. The most common flight departure time for this route is 11:00AM, with 51% of daily flights taking off at noon.

How many flights depart from South Carolina to Chicago on average per week?

The number of flights available between South Carolina and Chicago is 731 per week as of September 2025. The most frequent departure day is Mon, with 16% of weekly flights leaving on this day.

How long does it take to fly to Chicago?

Cheap South Carolina to Chicago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago

Best Price Found

Fastest flight time

Direct flights

Airports in Chicago

When did momondo last update prices for flights from South Carolina to Chicago?

How many operators does momondo search for flights from South Carolina to Chicago?

How old do you have to be to fly from South Carolina to Chicago?

What documentation or ID do you need to fly to Chicago?

What is the most popular plane model from South Carolina to Chicago?

Best airlines flying from South Carolina to Chicago

Compare and see reviews for airlines that fly from South Carolina to Chicago with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Chicago?

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago