What airlines fly to Chicago?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Chicago from South Carolina according to our data. United Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 5 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Chicago?

Average flight duration from South Carolina to Chicago depends on which airport you fly into and out of. Flying from Greenville to Chicago O'Hare Intl Airport is 2h 12m on average, while flying from Charleston to Chicago O'Hare Intl Airport is 2h 20m on average. Chicago O'Hare Intl Airport is the most popular airport in Chicago.

How many flights depart from South Carolina to Chicago on average per week?

The number of flights available between South Carolina and Chicago is 661 per week as of November 2025. The most frequent departure day is Wed, with 17% of weekly flights leaving on this day.

How many flights depart from South Carolina to Chicago on average per day?

As of November 2025, 94 flights take off from South Carolina and land in Chicago each day. The most common flight departure time for this route is 5:00PM, with 53% of daily flights taking off in the afternoon.

What is the cheapest airline that flies from South Carolina to Chicago?

Frontier, Southwest, and United Airlines are the most popular carriers operating from South Carolina to Chicago

When did momondo last update prices for flights from South Carolina to Chicago?

Prices for flights from South Carolina to Chicago are updated daily.

How many operators does momondo search for flights from South Carolina to Chicago?

The number of operators available for flights from South Carolina to Chicago is 7 as of November 2025.

How old do you have to be to fly from South Carolina to Chicago?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago.

What documentation or ID do you need to fly to Chicago?

The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$50 Cheap Flights from South Carolina to Chicago in 2025/26

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One-way

Last minute

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Cheap round-trip flights

Enter your travel dates to find the best prices.

9:27 am - 10:40 amCLT-ORD

2h 13mnonstop

11:53 am - 3:00 pmORD-CLT

2h 07mnonstop

$90Frontier

Find Deal

Thu, Dec 25 - Thu, Jan 8

3:45 pm - 5:07 pmCLT-ORD

2h 22mnonstop

11:53 am - 3:00 pmORD-CLT

2h 07mnonstop

$91Frontier

Find Deal

Fri, Jan 9 - Sun, Jan 11

6:20 pm - 7:25 pmCLT-MDW

2h 05mnonstop

6:00 pm - 8:50 pmMDW-CLT

1h 50mnonstop

$139Southwest

Find Deal

Thu, Dec 25 - Wed, Dec 31

7:00 am - 1:57 pmSAV-ORD

7h 57m1 stop

3:20 pm - 11:18 pmORD-SAV

6h 58m1 stop

$145Multiple Airlines

Find Deal

Thu, Dec 11 - Sun, Dec 14

6:10 am - 7:15 amCLT-MDW

2h 05mnonstop

6:35 am - 12:20 pmMDW-CLT

4h 45m1 stop

$149Southwest

Find Deal

Thu, Dec 25 - Thu, Jan 1

8:00 am - 10:31 pmSAV-ORD

15h 31m1 stop

12:00 pm - 5:13 pmORD-SAV

28h 13m1 stop

$154Multiple Airlines

Find Deal

Thu, Jan 29 - Sat, Jan 31

9:54 am - 8:01 pmMYR-ORD

11h 07m1 stop

7:20 am - 1:20 pmORD-MYR

5h 00m1 stop

$164Spirit Airlines

Find Deal

Thu, Dec 4 - Mon, Dec 8

9:54 am - 8:01 pmMYR-ORD

11h 07m1 stop

7:20 am - 1:20 pmORD-MYR

5h 00m1 stop

$167Spirit Airlines

Find Deal

Fri, Dec 5 - Mon, Dec 8

5:21 pm - 10:54 pmSAV-ORD

6h 33m1 stop

6:04 am - 4:22 pmORD-SAV

9h 18m1 stop

$173JetBlue

Find Deal

Fri, Feb 27 - Mon, Mar 2

7:00 am - 12:50 pmCHS-ORD

6h 50m1 stop

1:45 pm - 11:07 pmORD-CHS

8h 22m1 stop

$284JetBlue

Find Deal

Fri, Apr 3 - Mon, Apr 6

Spirit Airlines flights from South Carolina to Chicago

Our best Spirit Airlines deals on South Carolina to Chicago flight tickets

Spirit Airlines

Dec 4

MYR9:54 amMyrtle Beach Intl

11h 07m

1 stop

ORD8:01 pmChicago O'Hare Intl

Dec 8

ORD7:20 amChicago O'Hare Intl

5h 00m

1 stop

MYR1:20 pmMyrtle Beach Intl

$164

Find similar

Spirit Airlines

Dec 5

MYR9:54 amMyrtle Beach Intl

11h 07m

1 stop

ORD8:01 pmChicago O'Hare Intl

Dec 8

ORD7:20 amChicago O'Hare Intl

5h 00m

1 stop

MYR1:20 pmMyrtle Beach Intl

$167

Find similar

Spirit Airlines

Dec 4

MYR9:54 amMyrtle Beach Intl

11h 07m

1 stop

ORD8:01 pmChicago O'Hare Intl

Dec 6

ORD7:20 amChicago O'Hare Intl

5h 00m

1 stop

MYR1:20 pmMyrtle Beach Intl

$168

Find similar

Frontier flights from South Carolina to Chicago

Our best Frontier deals on South Carolina to Chicago flight tickets

Frontier

Nov 27

CLT4:17 pmCharlotte Douglas

2h 22m

ORD5:39 pmChicago O'Hare Intl

Dec 4

ORD5:15 amChicago O'Hare Intl

2h 07m

CLT8:22 amCharlotte Douglas

$89

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Frontier

Dec 25

CLT9:27 amCharlotte Douglas

2h 13m

ORD10:40 amChicago O'Hare Intl

Jan 8

ORD11:53 amChicago O'Hare Intl

2h 07m

CLT3:00 pmCharlotte Douglas

$90

Find similar

Frontier

Jan 9

CLT3:45 pmCharlotte Douglas

2h 22m

ORD5:07 pmChicago O'Hare Intl

Jan 11

ORD11:53 amChicago O'Hare Intl

2h 07m

CLT3:00 pmCharlotte Douglas

$91

Find similar

Fly from

Fly to

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 12/25

9:27 am-10:40 am

Nonstop2h 13m

Chicago O'Hare Intl

Thu 1/8

11:53 am-3:00 pm

Nonstop2h 07m

$90

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Fri 1/9

3:45 pm-5:07 pm

Nonstop2h 22m

Chicago O'Hare Intl

Sun 1/11

11:53 am-3:00 pm

Nonstop2h 07m

$91

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 12/25

6:20 pm-7:25 pm

Nonstop2h 05m

Chicago Midway

Wed 12/31

6:00 pm-8:50 pm

Nonstop1h 50m

$139

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Thu 12/11

7:00 am-1:57 pm

1 stop7h 57m

Chicago O'Hare Intl

Sun 12/14

3:20 pm-11:18 pm

1 stop6h 58m

$145

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 12/25

6:10 am-7:15 am

Nonstop2h 05m

Chicago Midway

Thu 1/1

6:35 am-12:20 pm

1 stop4h 45m

$149

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Thu 1/29

8:00 am-10:31 pm

1 stop15h 31m

Chicago O'Hare Intl

Sat 1/31

12:00 pm-5:13 pm

1 stop28h 13m

$154

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 12/4

9:54 am-8:01 pm

1 stop11h 07m

Chicago O'Hare Intl

Mon 12/8

7:20 am-1:20 pm

1 stop5h 00m

$164

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 12/5

9:54 am-8:01 pm

1 stop11h 07m

Chicago O'Hare Intl

Mon 12/8

7:20 am-1:20 pm

1 stop5h 00m

$167

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Fri 2/27

5:21 pm-10:54 pm

1 stop6h 33m

Chicago O'Hare Intl

Mon 3/2

6:04 am-4:22 pm

1 stop9h 18m

$173

CharlestonChicago

CHS - ORD

CHSORD

Charleston

Fri 4/3

7:00 am-12:50 pm

1 stop6h 50m

Chicago O'Hare Intl

Mon 4/6

1:45 pm-11:07 pm

1 stop8h 22m

$284

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from South Carolina, with most prices found around $284. If you’re not able to fly to Chicago in August, then September is your next best option. Flight prices from South Carolina to Chicago during September average around $310.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $405. This is often the case because there is less demand to fly during this day of the week. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Chicago for around $579.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the evening. Flights from South Carolina to Chicago during this time can be as low as $372. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $496.

What is the cheapest South Carolina to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best South Carolina - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from South Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $375 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from South Carolina for as low as $283 on momondo.

What cabin class options are available on South Carolina to Chicago flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago flights?

You could potentially save up to 29% on your flight if you consider stops on a South Carolina to Chicago flight.

Cheap South Carolina to Chicago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago

Best Price Found	$184
Fastest flight time	2h 00m
Direct flights	Every day
Airports in Chicago	2 airports

The best one-way flight to Chicago from South Carolina in the past 72 hours is $184. The best round-trip flight deal from South Carolina to Chicago found on momondo in the last 72 hours is $294.

The fastest flight from South Carolina to Chicago takes 2h 00m

Direct flights go from South Carolina to Chicago every day.

There are 2 airports near Chicago: Chicago O'Hare Intl (ORD), Chicago Midway (MDW)

Search flight deals

When did momondo last update prices for flights from South Carolina to Chicago?
Prices for flights from South Carolina to Chicago are updated daily.
How many operators does momondo search for flights from South Carolina to Chicago?
The number of operators available for flights from South Carolina to Chicago is 7 as of November 2025.
How old do you have to be to fly from South Carolina to Chicago?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Chicago.
What documentation or ID do you need to fly to Chicago?
The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from South Carolina to Chicago?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from South Carolina to Chicago is Embraer 175 (Enhanced Winglets) (22.76% of total bookings). The next most popular plane models are Embraer 175 (15.40%), Canadair (Bombardier) Regional Jet CRJ-550 (11.89%), and Embraer 170 (11.49%).

Best airlines flying from South Carolina to Chicago

Compare and see reviews for airlines that fly from South Carolina to Chicago with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $93	Free Cancellation	Rating 6.3 8,159 reviews	Search Spirit Airlines flights
American Airlines	PriceFrom $135	Free Cancellation	Rating 7.2 11,047 reviews	Search American Airlines flights
Delta	PriceFrom $180	Free Cancellation	Rating 7.9 8,002 reviews	Search Delta flights
Southwest	PriceFrom $190	Free Cancellation	Rating 8.0 4,251 reviews	Search Southwest flights
United Airlines	PriceFrom $193	Free Cancellation	Rating 7.4 9,028 reviews	Search United Airlines flights

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New Buffalo

Hammond

Benton Harbor

Saint Joseph

Portage

Lansing

Schererville

Valparaiso

Crown Point

Munster

Chesterton

Monticello

Porter

Griffith

Saint John

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from South Carolina.

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

All flight searches from South Carolina to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Chicago Midway Airport

Chicago O'Hare Intl Airport

Chicago Greater Rockford Airport

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Cheap flights from South Carolina to Chicago from $50

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Chicago departing on 2/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from South Carolina to Chicago

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Cheap last minute flights

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Spirit Airlines flights from South Carolina to Chicago

Our best Spirit Airlines deals on South Carolina to Chicago flight tickets

Frontier flights from South Carolina to Chicago

Our best Frontier deals on South Carolina to Chicago flight tickets

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Use the filters below to find and compare flights from South Carolina to Chicago that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from South Carolina to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

What is the cheapest day to depart on your flight to Chicago?

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the evening. Flights from South Carolina to Chicago during this time can be as low as $372. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $496.

What is the cheapest South Carolina to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best South Carolina - Chicago flight prices

How far in advance should I book a flight to Chicago?

What cabin class options are available on South Carolina to Chicago flights?

There are 4 cabin classes available to choose from on South Carolina to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on South Carolina to Chicago flights?

You could potentially save up to 29% on your flight if you consider stops on a South Carolina to Chicago flight.

What is the cheapest airline that flies from South Carolina to Chicago?

Frontier, Southwest, and United Airlines are the most popular carriers operating from South Carolina to Chicago

What airlines fly to Chicago?

How many flights depart from South Carolina to Chicago on average per day?

As of November 2025, 94 flights take off from South Carolina and land in Chicago each day. The most common flight departure time for this route is 5:00PM, with 53% of daily flights taking off in the afternoon.

How many flights depart from South Carolina to Chicago on average per week?

The number of flights available between South Carolina and Chicago is 661 per week as of November 2025. The most frequent departure day is Wed, with 17% of weekly flights leaving on this day.

How long does it take to fly to Chicago?

Cheap South Carolina to Chicago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Chicago

Best Price Found

Fastest flight time

Direct flights

Airports in Chicago

When did momondo last update prices for flights from South Carolina to Chicago?

How many operators does momondo search for flights from South Carolina to Chicago?

How old do you have to be to fly from South Carolina to Chicago?

What documentation or ID do you need to fly to Chicago?

What is the most popular plane model from South Carolina to Chicago?

Best airlines flying from South Carolina to Chicago

Compare and see reviews for airlines that fly from South Carolina to Chicago with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Chicago?

Can I find flights from South Carolina to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Chicago?

I’m not ready to book a flight from South Carolina to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago