What is the cheapest airline that flies from Santo Domingo Las Americas to South Carolina?

Frontier, Spirit Airlines, and American Airlines are the most popular carriers operating from Santo Domingo Las Americas to South Carolina

When did momondo last update prices for flights from Santo Domingo Las Americas Airport to South Carolina?

Prices for flights from Santo Domingo Las Americas Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Santo Domingo Las Americas Airport to South Carolina?

As of March 2026, there are 3 operators available to choose from for flights from Santo Domingo Las Americas Airport to South Carolina.

How old do you have to be to fly from Santo Domingo Las Americas Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$153 Cheap Flights from Santo Domingo to South Carolina in 2026

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Find the cheapest flights from Santo Domingo to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

3:01 pm - 12:25 am

SDQ

CLT

9h 24m

1 stop

6:45 am - 1:56 pm

CLT

SDQ

7h 11m

1 stop

$285Frontier

Wed, Apr 1 - Mon, Apr 6

3:01 pm - 12:25 am

SDQ

CLT

9h 24m

1 stop

6:15 am - 2:20 pm

CLT

SDQ

8h 05m

1 stop

$307Frontier

Wed, Apr 1 - Fri, Apr 10

2:52 am - 2:17 pm

SDQ

CLT

11h 25m

1 stop

7:00 am - 1:56 pm

CLT

SDQ

6h 56m

1 stop

$317Multiple Airlines

Mon, Mar 23 - Wed, Apr 1

2:52 am - 2:17 pm

SDQ

CLT

11h 25m

1 stop

7:00 am - 1:56 pm

CLT

SDQ

6h 56m

1 stop

$321Multiple Airlines

Tue, Mar 24 - Wed, Apr 1

12:41 pm - 2:18 pm

SDQ

CLT

25h 37m

2 stops

7:12 am - 5:29 am

CLT

SDQ

22h 17m

1 stop

$330Multiple Airlines

Wed, Apr 15 - Tue, Apr 21

2:49 pm - 10:56 pm

SDQ

CHS

8h 07m

1 stop

6:30 am - 1:12 pm

CHS

SDQ

6h 42m

1 stop

$385Delta

Fri, May 15 - Mon, Aug 31

6:05 am - 11:59 pm

SDQ

CHS

17h 54m

2 stops

5:15 am - 12:41 am

CHS

SDQ

19h 26m

2 stops

$395Delta

Fri, May 15 - Sat, May 30

4:00 pm - 12:24 am

SDQ

CHS

8h 24m

1 stop

8:09 pm - 9:20 am

CHS

SDQ

13h 11m

1 stop

$404American Airlines

Fri, May 1 - Mon, May 4

6:00 am - 12:24 am

SDQ

CHS

18h 24m

1 stop

5:50 am - 1:35 pm

CHS

SDQ

7h 45m

1 stop

$410American Airlines

Fri, May 15 - Mon, Aug 31

4:05 am - 4:57 pm

SDQ

CHS

12h 52m

1 stop

4:00 pm - 1:44 am

CHS

SDQ

9h 44m

1 stop

$418JetBlue

Mon, May 11 - Fri, May 29

Frontier flights from Santo Domingo to South Carolina

Our best Frontier deals on Santo Domingo to South Carolina flight tickets

Frontier

Apr 1

SDQ3:01 pmSanto Domingo Las Americas

9h 24m

1 stop

CLT12:25 amCharlotte Douglas

Apr 6

CLT6:45 amCharlotte Douglas

7h 11m

1 stop

SDQ1:56 pmSanto Domingo Las Americas

$285

Frontier

Apr 1

SDQ3:01 pmSanto Domingo Las Americas

9h 24m

1 stop

CLT12:25 amCharlotte Douglas

Apr 10

CLT6:15 amCharlotte Douglas

8h 05m

1 stop

SDQ2:20 pmSanto Domingo Las Americas

$307

Frontier

Apr 1

SDQ3:01 pmSanto Domingo Las Americas

9h 24m

1 stop

CLT12:25 amCharlotte Douglas

Apr 4

CLT3:02 pmCharlotte Douglas

19h 37m

1 stop

SDQ10:39 amSanto Domingo Las Americas

$380

Spirit Airlines flights from Santo Domingo to South Carolina

Our best Spirit Airlines deals on Santo Domingo to South Carolina flight tickets

Spirit Airlines

Mar 24

SDQ2:52 amSanto Domingo Las Americas

7h 19m

2 stops

CLT10:11 amCharlotte Douglas

Mar 25

CLT1:20 pmCharlotte Douglas

12h 18m

1 stop

SDQ1:38 amSanto Domingo Las Americas

$358

Spirit Airlines

Mar 24

SDQ2:52 amSanto Domingo Las Americas

7h 19m

2 stops

CLT10:11 amCharlotte Douglas

Mar 25

CLT1:20 pmCharlotte Douglas

12h 18m

1 stop

SDQ1:38 amSanto Domingo Las Americas

$362

Spirit Airlines

Mar 23

SDQ2:52 amSanto Domingo Las Americas

17h 25m

1 stop

CLT8:17 pmCharlotte Douglas

Apr 29

CLT9:54 pmCharlotte Douglas

15h 35m

1 stop

SDQ1:29 pmSanto Domingo Las Americas

$378

momondo Fare Finder

Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Wed 4/1

3:01 pm-12:25 am

1 stop9h 24m

Charlotte Douglas

Mon 4/6

6:45 am-1:56 pm

1 stop7h 11m

$285

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Wed 4/1

3:01 pm-12:25 am

1 stop9h 24m

Charlotte Douglas

Fri 4/10

6:15 am-2:20 pm

1 stop8h 05m

$307

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Mon 3/23

2:52 am-2:17 pm

1 stop11h 25m

Charlotte Douglas

Wed 4/1

7:00 am-1:56 pm

1 stop6h 56m

$317

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Tue 3/24

2:52 am-2:17 pm

1 stop11h 25m

Charlotte Douglas

Wed 4/1

7:00 am-1:56 pm

1 stop6h 56m

$321

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Wed 4/15

12:41 pm-2:18 pm

2 stops25h 37m

Charlotte Douglas

Tue 4/21

7:12 am-5:29 am

1 stop22h 17m

$330

Quickest round-trip

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/15

2:49 pm-10:56 pm

1 stop8h 07m

Charleston

Mon 8/31

6:30 am-1:12 pm

1 stop6h 42m

$385

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/15

6:05 am-11:59 pm

2 stops17h 54m

Charleston

Sat 5/30

5:15 am-12:41 am

2 stops19h 26m

$395

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/1

4:00 pm-12:24 am

1 stop8h 24m

Charleston

Mon 5/4

8:09 pm-9:20 am

1 stop13h 11m

$404

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 5/15

6:00 am-12:24 am

1 stop18h 24m

Charleston

Mon 8/31

5:50 am-1:35 pm

1 stop7h 45m

$410

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 5/11

4:05 am-4:57 pm

1 stop12h 52m

Charleston

Fri 5/29

4:00 pm-1:44 am

1 stop9h 44m

$418

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santo Domingo to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Santo Domingo to South Carolina flights?

You could potentially save up to 18% on your flight if you consider stops on a Santo Domingo to South Carolina flight.

Cheap Santo Domingo to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to South Carolina

Fastest flight time	6h 14m
Direct flights	None

The fastest flight from Santo Domingo to South Carolina takes 6h 14m

There are no direct flights from Santo Domingo to South Carolina. There are no popular flight routes from Santo Domingo to South Carolina.

Search flight deals

When did momondo last update prices for flights from Santo Domingo Las Americas Airport to South Carolina?
Prices for flights from Santo Domingo Las Americas Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Santo Domingo Las Americas Airport to South Carolina?
As of March 2026, there are 3 operators available to choose from for flights from Santo Domingo Las Americas Airport to South Carolina.
How old do you have to be to fly from Santo Domingo Las Americas Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Santo Domingo.

Can I find flights from Santo Domingo to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to South Carolina?

momondo helps you find the best flight between Santo Domingo and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.