What is the cheapest airline that flies from Santo Domingo Las Americas to South Carolina?

American Airlines and United Airlines are the most popular carriers operating from Santo Domingo Las Americas to South Carolina

When did momondo last update prices for flights from Santo Domingo Las Americas Airport to South Carolina?

Prices for flights from Santo Domingo Las Americas Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Santo Domingo Las Americas Airport to South Carolina?

As of August 2026, there are 2 operators available to choose from for flights from Santo Domingo Las Americas Airport to South Carolina.

How old do you have to be to fly from Santo Domingo Las Americas Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$238 Cheap Flights from Santo Domingo to South Carolina in 2026

Find the cheapest flights from Santo Domingo to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:53 pm - 11:59 pmSDQ Santo Domingo Las Americas-CHS Charleston

9h 06m1 stop Atlanta Hartsfield-Jackson

6:00 am - 5:29 pmCHS Charleston-SDQ Santo Domingo Las Americas

11h 29m1 stop New York John F Kennedy Intl

$443JetBlue

Fri, Sep 18 - Fri, Oct 2

3:30 pm - 8:01 amSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

16h 31m2 stops San Juan Luis Munoz Marin Intl Orlando

9:59 pm - 4:29 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

18h 30m1 stop Miami

$469Multiple Airlines

Sat, Sep 5 - Tue, Sep 22

3:35 pm - 1:55 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

22h 20m1 stop Miami

9:41 pm - 9:45 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

24h 04m1 stop Miami

$487Multiple Airlines

Tue, Sep 29 - Fri, Oct 23

3:35 pm - 1:55 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

22h 20m1 stop Miami

11:27 am - 9:45 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

10h 18m1 stop Miami

$488Multiple Airlines

Tue, Sep 29 - Sun, Oct 4

10:27 am - 11:59 pmSDQ Santo Domingo Las Americas-CHS Charleston

13h 32m1 stop Miami

6:20 pm - 9:21 amCHS Charleston-SDQ Santo Domingo Las Americas

15h 01m1 stop Miami

$491American Airlines

Fri, Sep 4 - Fri, Sep 18

9:30 am - 9:36 pmSDQ Santo Domingo Las Americas-CHS Charleston

12h 06m1 stop Miami

6:00 am - 3:17 pmCHS Charleston-SDQ Santo Domingo Las Americas

9h 17m1 stop Miami

$491American Airlines

Wed, Sep 30 - Sat, Oct 3

10:27 am - 11:56 pmSDQ Santo Domingo Las Americas-CHS Charleston

13h 29m2 stops Miami Philadelphia

6:00 am - 8:50 pmCHS Charleston-SDQ Santo Domingo Las Americas

14h 50m2 stops Philadelphia Miami

$495American Airlines

Wed, Oct 14 - Sun, Oct 18

2:29 pm - 11:20 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

8h 51m1 stop Fort Lauderdale

6:50 am - 3:16 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

8h 26m1 stop Fort Lauderdale

$543JetBlue

Fri, Sep 25 - Thu, Oct 15

1:32 pm - 11:05 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

9h 33m1 stop Fort Lauderdale

9:00 am - 3:16 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

6h 16m1 stop Fort Lauderdale

$543JetBlue

Wed, Oct 21 - Wed, Oct 28

2:29 pm - 11:20 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

8h 51m1 stop Fort Lauderdale

3:10 pm - 11:59 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

8h 49m1 stop Fort Lauderdale

$543JetBlue

Fri, Sep 25 - Thu, Oct 15

Cheap last minute flights

Enter your travel dates to find the best prices.

12:41 pm - 2:20 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

25h 39m2 stops San Juan Luis Munoz Marin Intl Fort Lauderdale

9:59 pm - 4:29 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

18h 30m1 stop Miami

$631Multiple Airlines

Mon, Aug 17 - Thu, Sep 17

12:41 pm - 7:33 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

6h 52m1 stop San Juan Luis Munoz Marin Intl

9:59 pm - 4:29 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

18h 30m1 stop Miami

$777Multiple Airlines

Mon, Aug 17 - Thu, Sep 17

12:41 pm - 7:33 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

6h 52m1 stop San Juan Luis Munoz Marin Intl

9:52 pm - 7:18 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

21h 26m2 stops Orlando San Juan Luis Munoz Marin Intl

$806Multiple Airlines

Mon, Aug 17 - Sat, Sep 5

2:05 pm - 10:58 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

8h 53m1 stop New York John F Kennedy Intl

10:01 am - 6:06 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

8h 05m1 stop New York John F Kennedy Intl

$1,025Delta

Thu, Aug 20 - Thu, Sep 3

6:00 am - 4:55 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

10h 55m1 stop Newark

7:00 am - 10:46 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

15h 46m1 stop Newark

$1,049United Airlines

Thu, Aug 20 - Sat, Sep 5

2:05 pm - 10:58 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

8h 53m1 stop New York John F Kennedy Intl

1:17 pm - 12:54 amCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

11h 37m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl

$1,073Delta

Thu, Aug 20 - Sat, Sep 5

2:05 pm - 10:58 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

8h 53m1 stop New York John F Kennedy Intl

6:00 am - 6:06 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

12h 06m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl

$1,132Delta

Thu, Aug 20 - Thu, Sep 3

2:17 pm - 9:44 amSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

19h 27m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

10:25 am - 11:42 amCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

25h 17m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

$1,168Copa Airlines

Thu, Aug 20 - Sat, Sep 5

7:35 pm - 1:09 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

17h 34m1 stop New York John F Kennedy Intl

11:01 am - 6:06 pmCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

7h 05m1 stop New York John F Kennedy Intl

$1,210JetBlue

Mon, Aug 17 - Sat, Sep 5

6:42 pm - 6:56 pmSDQ Santo Domingo Las Americas-CLT Charlotte Douglas

24h 14m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

10:25 am - 2:25 amCLT Charlotte Douglas-SDQ Santo Domingo Las Americas

16h 00m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl

$1,240Copa Airlines

Mon, Aug 17 - Sat, Sep 5

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JetBlue flights from Santo Domingo to South Carolina

Our best JetBlue deals on Santo Domingo to South Carolina flight tickets

JetBlue

Sep 18

SDQ2:53 pmSanto Domingo Las Americas

9h 06m

1 stop

CHS11:59 pmCharleston

Oct 2

CHS6:00 amCharleston

11h 29m

1 stop

SDQ5:29 pmSanto Domingo Las Americas

$443

JetBlue

Oct 14

SDQ5:01 amSanto Domingo Las Americas

9h 14m

1 stop

CLT2:15 pmCharlotte Douglas

Oct 24

CLT6:50 amCharlotte Douglas

5h 32m

1 stop

SDQ12:22 pmSanto Domingo Las Americas

$543

JetBlue

Oct 2

SDQ2:29 pmSanto Domingo Las Americas

8h 51m

1 stop

CLT11:20 pmCharlotte Douglas

Oct 23

CLT6:50 amCharlotte Douglas

8h 26m

1 stop

SDQ3:16 pmSanto Domingo Las Americas

$560

Delta flights from Santo Domingo to South Carolina

Our best Delta deals on Santo Domingo to South Carolina flight tickets

Delta

Sep 5

SDQ7:35 pmSanto Domingo Las Americas

15h 08m

1 stop

CHS10:43 amCharleston

Sep 16

CHS6:40 amCharleston

6h 47m

1 stop

SDQ1:27 pmSanto Domingo Las Americas

$658

Delta

Sep 5

SDQ7:35 pmSanto Domingo Las Americas

18h 17m

2 stops

CHS1:52 pmCharleston

Sep 17

CHS6:00 amCharleston

12h 07m

1 stop

SDQ6:07 pmSanto Domingo Las Americas

$663

Delta

Sep 2

SDQ6:05 amSanto Domingo Las Americas

10h 22m

1 stop

CHS4:27 pmCharleston

Sep 18

CHS6:00 amCharleston

12h 07m

1 stop

SDQ6:07 pmSanto Domingo Las Americas

$706

momondo Fare Finder

Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoCharleston

SDQ Santo Domingo Las Americas - CHS Charleston

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:53 pm-11:59 pm

1 stop9h 06m

Charleston

Fri 10/2

6:00 am-5:29 pm

1 stop11h 29m

$443

Santo DomingoCharlotte

SDQ Santo Domingo Las Americas - CLT Charlotte Douglas

SDQCLT

Santo Domingo Las Americas

Sat 9/5

3:30 pm-8:01 am

2 stops16h 31m

Charlotte Douglas

Tue 9/22

9:59 pm-4:29 pm

1 stop18h 30m

$469

Santo DomingoCharlotte

SDQ Santo Domingo Las Americas - CLT Charlotte Douglas

SDQCLT

Santo Domingo Las Americas

Tue 9/29

3:35 pm-1:55 pm

1 stop22h 20m

Charlotte Douglas

Fri 10/23

9:41 pm-9:45 pm

1 stop24h 04m

$487

Santo DomingoCharlotte

SDQ Santo Domingo Las Americas - CLT Charlotte Douglas

SDQCLT

Santo Domingo Las Americas

Tue 9/29

3:35 pm-1:55 pm

1 stop22h 20m

Charlotte Douglas

Sun 10/4

11:27 am-9:45 pm

1 stop10h 18m

$488

Santo DomingoCharleston

SDQ Santo Domingo Las Americas - CHS Charleston

SDQCHS

Santo Domingo Las Americas

Fri 9/4

10:27 am-11:59 pm

1 stop13h 32m

Charleston

Fri 9/18

6:20 pm-9:21 am

1 stop15h 01m

$491

Santo DomingoCharleston

SDQ Santo Domingo Las Americas - CHS Charleston

SDQCHS

Santo Domingo Las Americas

Wed 9/30

9:30 am-9:36 pm

1 stop12h 06m

Charleston

Sat 10/3

6:00 am-3:17 pm

1 stop9h 17m

$491

Santo DomingoCharleston

SDQ Santo Domingo Las Americas - CHS Charleston

SDQCHS

Santo Domingo Las Americas

Wed 10/14

10:27 am-11:56 pm

2 stops13h 29m

Charleston

Sun 10/18

6:00 am-8:50 pm

2 stops14h 50m

$495

Santo DomingoCharlotte

SDQ Santo Domingo Las Americas - CLT Charlotte Douglas

SDQCLT

Santo Domingo Las Americas

Fri 9/25

2:29 pm-11:20 pm

1 stop8h 51m

Charlotte Douglas

Thu 10/15

6:50 am-3:16 pm

1 stop8h 26m

$543

Quickest round-trip

Santo DomingoCharlotte

SDQ Santo Domingo Las Americas - CLT Charlotte Douglas

SDQCLT

Santo Domingo Las Americas

Wed 10/21

1:32 pm-11:05 pm

1 stop9h 33m

Charlotte Douglas

Wed 10/28

9:00 am-3:16 pm

1 stop6h 16m

$543

Santo DomingoCharlotte

SDQ Santo Domingo Las Americas - CLT Charlotte Douglas

SDQCLT

Santo Domingo Las Americas

Fri 9/25

2:29 pm-11:20 pm

1 stop8h 51m

Charlotte Douglas

Thu 10/15

3:10 pm-11:59 pm

1 stop8h 49m

$543

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santo Domingo to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Santo Domingo to South Carolina flights?

You could potentially save up to 41% on your flight if you consider stops on a Santo Domingo to South Carolina flight.

Cheap Santo Domingo to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to South Carolina

Fastest flight time	6h 45m
Direct flights	None

The fastest flight from Santo Domingo to South Carolina takes 6h 45m

There are no direct flights from Santo Domingo to South Carolina. There are no popular flight routes from Santo Domingo to South Carolina.

Search flight deals

Frequently asked questions about flying from Santo Domingo to South Carolina

When did momondo last update prices for flights from Santo Domingo Las Americas Airport to South Carolina?
Prices for flights from Santo Domingo Las Americas Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Santo Domingo Las Americas Airport to South Carolina?
As of August 2026, there are 2 operators available to choose from for flights from Santo Domingo Las Americas Airport to South Carolina.
How old do you have to be to fly from Santo Domingo Las Americas Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Santo Domingo.

Can I find flights from Santo Domingo to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to South Carolina?

momondo helps you find the best flight between Santo Domingo and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.