What is the cheapest airline that flies from Santo Domingo Las Americas to South Carolina?

Frontier, American Airlines, and Delta are the most popular carriers operating from Santo Domingo Las Americas to South Carolina

When did momondo last update prices for flights from Santo Domingo Las Americas Airport to South Carolina?

Prices for flights from Santo Domingo Las Americas Airport to South Carolina were last updated today.

How many operators does momondo search for flights from Santo Domingo Las Americas Airport to South Carolina?

As of May 2026, there are 2 operators available to choose from for flights from Santo Domingo Las Americas Airport to South Carolina.

How old do you have to be to fly from Santo Domingo Las Americas Airport to South Carolina?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$160 Cheap Flights from Santo Domingo to South Carolina in 2026

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Find the cheapest flights from Santo Domingo to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:44 pm - 10:03 am

SDQ

CLT

19h 19m

1 stop

1:00 pm - 11:05 am

CLT

SDQ

22h 05m

1 stop

$332Frontier

Sat, May 23 - Wed, Jun 3

5:01 am - 4:31 pm

SDQ

CHS

11h 30m

1 stop

7:05 pm - 11:59 pm

CHS

SDQ

4h 54m

1 stop

$383JetBlue

Tue, Sep 1 - Sat, Sep 19

12:21 pm - 8:42 am

SDQ

CLT

20h 21m

1 stop

1:09 pm - 11:06 am

CLT

SDQ

21h 57m

1 stop

$384Frontier

Wed, Jun 17 - Wed, Jun 24

5:01 am - 4:31 pm

SDQ

CHS

11h 30m

1 stop

5:27 pm - 11:59 pm

CHS

SDQ

6h 32m

1 stop

$393JetBlue

Tue, Jul 14 - Tue, Aug 4

5:01 am - 4:31 pm

SDQ

CHS

11h 30m

1 stop

5:27 pm - 11:59 pm

CHS

SDQ

6h 32m

1 stop

$398JetBlue

Tue, Jul 14 - Tue, Aug 4

7:40 pm - 10:22 am

SDQ

CHS

14h 42m

1 stop

7:41 pm - 1:22 pm

CHS

SDQ

17h 41m

2 stops

$403American Airlines

Mon, Jul 27 - Tue, Aug 18

2:00 pm - 11:54 pm

SDQ

CHS

9h 54m

1 stop

7:39 am - 2:20 pm

CHS

SDQ

6h 41m

1 stop

$408American Airlines

Wed, Sep 2 - Wed, Sep 16

2:22 pm - 8:28 am

SDQ

CHS

18h 06m

2 stops

7:21 am - 2:20 pm

CHS

SDQ

6h 59m

2 stops

$412American Airlines

Wed, Sep 2 - Wed, Sep 16

1:10 pm - 10:39 am

SDQ

CAE

21h 29m

1 stop

11:18 am - 10:46 pm

CAE

SDQ

11h 28m

1 stop

$1,364United Airlines

Thu, May 28 - Sun, May 31

6:00 am - 10:39 am

SDQ

CAE

28h 39m

1 stop

11:18 am - 2:10 pm

CAE

SDQ

26h 52m

1 stop

$1,370United Airlines

Thu, May 28 - Sun, May 31

Frontier flights from Santo Domingo to South Carolina

Our best Frontier deals on Santo Domingo to South Carolina flight tickets

Frontier

May 23

SDQ2:44 pmSanto Domingo Las Americas

19h 19m

1 stop

CLT10:03 amCharlotte Douglas

Jun 3

CLT1:00 pmCharlotte Douglas

22h 05m

1 stop

SDQ11:05 amSanto Domingo Las Americas

$332

Frontier

Jun 17

SDQ12:21 pmSanto Domingo Las Americas

20h 21m

1 stop

CLT8:42 amCharlotte Douglas

Jun 24

CLT1:09 pmCharlotte Douglas

21h 57m

1 stop

SDQ11:06 amSanto Domingo Las Americas

$384

Frontier

May 23

SDQ2:44 pmSanto Domingo Las Americas

19h 19m

1 stop

CLT10:03 amCharlotte Douglas

Jun 17

CLT1:09 pmCharlotte Douglas

21h 57m

1 stop

SDQ11:06 amSanto Domingo Las Americas

$420

Delta flights from Santo Domingo to South Carolina

Our best Delta deals on Santo Domingo to South Carolina flight tickets

Delta

Jul 18

SDQ6:05 amSanto Domingo Las Americas

10h 37m

1 stop

CHS4:42 pmCharleston

Aug 17

CHS5:10 pmCharleston

7h 44m

1 stop

SDQ12:54 amSanto Domingo Las Americas

$488

Delta

May 21

SDQ2:48 pmSanto Domingo Las Americas

8h 08m

1 stop

CHS10:56 pmCharleston

May 23

CHS6:00 amCharleston

12h 01m

1 stop

SDQ6:01 pmSanto Domingo Las Americas

$550

Delta

Aug 30

SDQ2:53 pmSanto Domingo Las Americas

7h 14m

1 stop

CHS10:07 pmCharleston

Sep 16

CHS5:30 amCharleston

12h 55m

2 stops

SDQ6:25 pmSanto Domingo Las Americas

$555

momondo Fare Finder

Use the filters below to find and compare flights from Santo Domingo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Sat 5/23

2:44 pm-10:03 am

1 stop19h 19m

Charlotte Douglas

Wed 6/3

1:00 pm-11:05 am

1 stop22h 05m

$332

Quickest round-trip

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 9/1

5:01 am-4:31 pm

1 stop11h 30m

Charleston

Sat 9/19

7:05 pm-11:59 pm

1 stop4h 54m

$383

Santo DomingoCharlotte

SDQ - CLT

SDQCLT

Santo Domingo Las Americas

Wed 6/17

12:21 pm-8:42 am

1 stop20h 21m

Charlotte Douglas

Wed 6/24

1:09 pm-11:06 am

1 stop21h 57m

$384

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 7/14

5:01 am-4:31 pm

1 stop11h 30m

Charleston

Tue 8/4

5:27 pm-11:59 pm

1 stop6h 32m

$393

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 7/14

5:01 am-4:31 pm

1 stop11h 30m

Charleston

Tue 8/4

5:27 pm-11:59 pm

1 stop6h 32m

$398

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 7/27

7:40 pm-10:22 am

1 stop14h 42m

Charleston

Tue 8/18

7:41 pm-1:22 pm

2 stops17h 41m

$403

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 9/2

2:00 pm-11:54 pm

1 stop9h 54m

Charleston

Wed 9/16

7:39 am-2:20 pm

1 stop6h 41m

$408

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 9/2

2:22 pm-8:28 am

2 stops18h 06m

Charleston

Wed 9/16

7:21 am-2:20 pm

2 stops6h 59m

$412

Santo DomingoColumbia

SDQ - CAE

SDQCAE

Santo Domingo Las Americas

Thu 5/28

1:10 pm-10:39 am

1 stop21h 29m

Columbia Metropolitan

Sun 5/31

11:18 am-10:46 pm

1 stop11h 28m

$1,364

Santo DomingoColumbia

SDQ - CAE

SDQCAE

Santo Domingo Las Americas

Thu 5/28

6:00 am-10:39 am

1 stop28h 39m

Columbia Metropolitan

Sun 5/31

11:18 am-2:10 pm

1 stop26h 52m

$1,370

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santo Domingo to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Santo Domingo to South Carolina flights?

You could potentially save up to 31% on your flight if you consider stops on a Santo Domingo to South Carolina flight.

Cheap Santo Domingo to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to South Carolina

Fastest flight time	6h 16m
Direct flights	None

The fastest flight from Santo Domingo to South Carolina takes 6h 16m

There are no direct flights from Santo Domingo to South Carolina. There are no popular flight routes from Santo Domingo to South Carolina.

Search flight deals

Frequently asked questions about flying from Santo Domingo to South Carolina

When did momondo last update prices for flights from Santo Domingo Las Americas Airport to South Carolina?
Prices for flights from Santo Domingo Las Americas Airport to South Carolina were last updated today.
How many operators does momondo search for flights from Santo Domingo Las Americas Airport to South Carolina?
As of May 2026, there are 2 operators available to choose from for flights from Santo Domingo Las Americas Airport to South Carolina.
How old do you have to be to fly from Santo Domingo Las Americas Airport to South Carolina?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to South Carolina?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South Carolina from Santo Domingo.

Can I find flights from Santo Domingo to South Carolina with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South Carolina from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to South Carolina?

momondo helps you find the best flight between Santo Domingo and South Carolina by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to South Carolina right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to South Carolina now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to South Carolina and let you know when they change.