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Cheap flights from Santo Domingo to Buffalo from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Buffalo departing on 10/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santo Domingo to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:53 pm - 11:52 pm
SDQ
-
BUF
8h 59m
1 stop
Delta Logo
6:05 am - 1:27 pm
BUF
-
SDQ
7h 22m
1 stop
$458Delta
Fri, Oct 2 - Sun, Oct 4
Delta Logo
2:53 pm - 11:59 pm
SDQ
-
BUF
9h 06m
1 stop
Delta Logo
10:00 am - 12:54 am
BUF
-
SDQ
14h 54m
1 stop
$458Delta
Thu, Aug 27 - Sun, Sep 6
Delta Logo
2:53 pm - 11:53 pm
SDQ
-
BUF
9h 00m
2 stops
Delta Logo
6:05 am - 1:27 pm
BUF
-
SDQ
7h 22m
1 stop
$458Delta
Fri, Oct 2 - Sun, Oct 4
JetBlue Logo
2:29 pm - 10:56 pm
SDQ
-
BUF
8h 27m
1 stop
JetBlue Logo
7:00 am - 2:49 pm
BUF
-
SDQ
7h 49m
1 stop
$477JetBlue
Fri, Oct 2 - Sun, Oct 4
JetBlue Logo
2:29 pm - 10:56 pm
SDQ
-
BUF
8h 27m
1 stop
JetBlue Logo
7:00 am - 2:49 pm
BUF
-
SDQ
7h 49m
1 stop
$477JetBlue
Fri, Oct 2 - Sat, Oct 3
JetBlue Logo
2:29 pm - 10:56 pm
SDQ
-
BUF
8h 27m
1 stop
JetBlue Logo
7:00 am - 2:49 pm
BUF
-
SDQ
7h 49m
1 stop
$479JetBlue
Fri, Oct 2 - Sun, Oct 4
Delta Logo
2:53 pm - 11:53 pm
SDQ
-
BUF
9h 00m
2 stops
Delta Logo
6:05 am - 1:27 pm
BUF
-
SDQ
7h 22m
1 stop
$519Delta
Fri, Oct 2 - Sun, Oct 4
JetBlue Logo
2:29 pm - 10:56 pm
SDQ
-
BUF
8h 27m
1 stop
JetBlue Logo
7:00 am - 3:25 pm
BUF
-
SDQ
8h 25m
1 stop
$536JetBlue
Fri, Oct 2 - Sat, Oct 3
JetBlue Logo
2:29 pm - 10:56 pm
SDQ
-
BUF
8h 27m
1 stop
JetBlue Logo
6:00 am - 5:56 pm
BUF
-
SDQ
11h 56m
1 stop
$543JetBlue
Fri, Oct 2 - Mon, Oct 5
JetBlue Logo
2:29 pm - 10:56 pm
SDQ
-
BUF
8h 27m
1 stop
JetBlue Logo
7:00 am - 2:49 pm
BUF
-
SDQ
7h 49m
1 stop
$550JetBlue
Fri, Oct 2 - Mon, Oct 5

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American Airlines flights from Santo Domingo to Buffalo

Our best American Airlines deals on Santo Domingo to Buffalo flight tickets
American Airlines
Aug 27
SDQ2:00 pmSanto Domingo Las Americas
26h 56m
1 stop
BUF4:56 pmBuffalo
Sep 6
BUF6:21 amBuffalo
12h 23m
2 stops
SDQ6:44 pmSanto Domingo Las Americas
$836
American Airlines
Dec 14
SDQ6:00 amSanto Domingo Las Americas
15h 09m
2 stops
BUF8:09 pmBuffalo
Dec 21
BUF7:15 pmBuffalo
13h 52m
2 stops
SDQ10:07 amSanto Domingo Las Americas
$1,031

United Airlines flights from Santo Domingo to Buffalo

Our best United Airlines deals on Santo Domingo to Buffalo flight tickets
United Airlines
Oct 2
SDQ1:10 pmSanto Domingo Las Americas
20h 19m
2 stops
BUF9:29 amBuffalo
Oct 5
BUF7:42 pmBuffalo
16h 13m
1 stop
SDQ11:55 amSanto Domingo Las Americas
$611
United Airlines
Oct 2
SDQ3:20 pmSanto Domingo Las Americas
18h 09m
2 stops
BUF9:29 amBuffalo
Oct 4
BUF10:46 amBuffalo
25h 09m
2 stops
SDQ11:55 amSanto Domingo Las Americas
$619
United Airlines
Oct 2
SDQ3:20 pmSanto Domingo Las Americas
18h 09m
2 stops
BUF9:29 amBuffalo
Oct 4
BUF10:46 amBuffalo
25h 09m
2 stops
SDQ11:55 amSanto Domingo Las Americas
$677

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:53 pm-11:52 pm

1 stop8h 59m

Buffalo

Sun 10/4

6:05 am-1:27 pm

1 stop7h 22m

$458

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 8/27

2:53 pm-11:59 pm

1 stop9h 06m

Buffalo

Sun 9/6

10:00 am-12:54 am

1 stop14h 54m

$458

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:53 pm-11:53 pm

2 stops9h 00m

Buffalo

Sun 10/4

6:05 am-1:27 pm

1 stop7h 22m

$458
Quickest round-trip

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:29 pm-10:56 pm

1 stop8h 27m

Buffalo

Sun 10/4

7:00 am-2:49 pm

1 stop7h 49m

$477

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:29 pm-10:56 pm

1 stop8h 27m

Buffalo

Sat 10/3

7:00 am-2:49 pm

1 stop7h 49m

$477

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:29 pm-10:56 pm

1 stop8h 27m

Buffalo

Sun 10/4

7:00 am-2:49 pm

1 stop7h 49m

$479

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:53 pm-11:53 pm

2 stops9h 00m

Buffalo

Sun 10/4

6:05 am-1:27 pm

1 stop7h 22m

$519

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:29 pm-10:56 pm

1 stop8h 27m

Buffalo

Sat 10/3

7:00 am-3:25 pm

1 stop8h 25m

$536

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:29 pm-10:56 pm

1 stop8h 27m

Buffalo

Mon 10/5

6:00 am-5:56 pm

1 stop11h 56m

$543

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 10/2

2:29 pm-10:56 pm

1 stop8h 27m

Buffalo

Mon 10/5

7:00 am-2:49 pm

1 stop7h 49m

$550

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Buffalo from

How to get the cheapest flight ticket from Santo Domingo to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Buffalo?

If you aren’t able to travel during the month of April, then book flights to Buffalo from Santo Domingo during January instead. Flights to Buffalo in January, while not as cheap as those in April, still average around $412.

Can stopping save me money on Santo Domingo to Buffalo flights?

You could potentially save up to 1% on your flight if you consider stops on a Santo Domingo to Buffalo flight.

How have Santo Domingo to Buffalo flight prices changed over time?

When to book flights from Santo Domingo to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Buffalo (SDQ to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Buffalo

Fastest flight time

7h 39m

Direct flights

None
The fastest flight from Santo Domingo to Buffalo takes 7h 39m
There are no direct flights from Santo Domingo to Buffalo. There are no popular flight routes from Santo Domingo to Buffalo.
Search flight deals

Frequently asked questions about flying from Santo Domingo to Buffalo

  • How far is Santo Domingo Las Americas to Buffalo by plane?

    Santo Domingo Las Americas and Buffalo are 1764.1 mi apart from one another. Typically, this will take 7h 39m by plane in normal conditions.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Buffalo Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Buffalo Airport refresh daily.

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The required travel and health documents for your Buffalo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Buffalo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Williamsville
Orchard Park
Grand Island
Bowmansville
West Seneca
Lockport
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santo Domingo.

Can I find flights from Santo Domingo to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santo Domingo which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santo Domingo to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Santo Domingo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santo Domingo to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

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