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Cheap flights from Santo Domingo to Buffalo from $217

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Buffalo departing on 5/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Santo Domingo to Buffalo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:05 am - 3:02 pm
SDQ
-
BUF
8h 57m
1 stop
Delta Logo
7:00 am - 6:01 pm
BUF
-
SDQ
11h 01m
1 stop
$401Delta
Thu, May 21 - Mon, Jun 1
Delta Logo
7:35 pm - 9:44 am
SDQ
-
BUF
14h 09m
1 stop
Delta Logo
7:00 am - 6:01 pm
BUF
-
SDQ
11h 01m
1 stop
$451Delta
Fri, May 15 - Tue, May 19
Delta Logo
2:49 pm - 11:59 pm
SDQ
-
BUF
9h 10m
1 stop
Delta Logo
7:00 am - 6:01 pm
BUF
-
SDQ
11h 01m
1 stop
$484Delta
Wed, May 13 - Tue, May 19
United Airlines Logo
6:00 am - 11:33 pm
SDQ
-
BUF
17h 33m
1 stop
United Airlines Logo
6:04 am - 10:46 pm
BUF
-
SDQ
16h 42m
2 stops
$490United Airlines
Thu, May 14 - Tue, May 19
JetBlue Logo
9:20 am - 9:05 pm
SDQ
-
BUF
11h 45m
1 stop
JetBlue Logo
6:16 pm - 8:09 am
BUF
-
SDQ
13h 53m
1 stop
$506JetBlue
Thu, Jun 4 - Mon, Jun 8
American Airlines Logo
10:25 am - 12:09 am
SDQ
-
BUF
13h 44m
2 stops
American Airlines Logo
5:25 am - 12:45 pm
BUF
-
SDQ
7h 20m
1 stop
$511American Airlines
Thu, May 21 - Mon, Jun 1
United Airlines Logo
6:00 am - 11:55 pm
SDQ
-
BUF
17h 55m
2 stops
United Airlines Logo
5:55 pm - 10:46 pm
BUF
-
SDQ
28h 51m
2 stops
$515United Airlines
Fri, May 15 - Mon, May 18
JetBlue Logo
9:20 am - 9:05 pm
SDQ
-
BUF
11h 45m
1 stop
JetBlue Logo
6:16 pm - 8:09 am
BUF
-
SDQ
13h 53m
1 stop
$517JetBlue
Thu, Jun 4 - Mon, Jun 8
United Airlines Logo
6:00 am - 11:59 pm
SDQ
-
BUF
17h 59m
2 stops
United Airlines Logo
6:00 am - 10:46 pm
BUF
-
SDQ
16h 46m
2 stops
$519United Airlines
Thu, May 21 - Mon, Jun 1
Delta Logo
7:35 pm - 9:44 am
SDQ
-
BUF
14h 09m
1 stop
Delta Logo
7:39 pm - 1:23 pm
BUF
-
SDQ
17h 44m
1 stop
$526Delta
Fri, May 15 - Fri, May 22

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United Airlines flights from Santo Domingo to Buffalo

Our best United Airlines deals on Santo Domingo to Buffalo flight tickets
United Airlines
May 14
SDQ6:00 amSanto Domingo Las Americas
17h 33m
1 stop
BUF11:33 pmBuffalo
May 19
BUF6:04 amBuffalo
16h 42m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
$490
United Airlines
May 15
SDQ6:00 amSanto Domingo Las Americas
17h 55m
2 stops
BUF11:55 pmBuffalo
May 18
BUF5:55 pmBuffalo
28h 51m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
$515
United Airlines
May 21
SDQ6:00 amSanto Domingo Las Americas
17h 59m
2 stops
BUF11:59 pmBuffalo
Jun 1
BUF6:00 amBuffalo
16h 46m
2 stops
SDQ10:46 pmSanto Domingo Las Americas
$519

Delta flights from Santo Domingo to Buffalo

Our best Delta deals on Santo Domingo to Buffalo flight tickets
Delta
May 21
SDQ6:05 amSanto Domingo Las Americas
8h 57m
1 stop
BUF3:02 pmBuffalo
Jun 1
BUF7:00 amBuffalo
11h 01m
1 stop
SDQ6:01 pmSanto Domingo Las Americas
$401
Delta
May 15
SDQ7:35 pmSanto Domingo Las Americas
14h 09m
1 stop
BUF9:44 amBuffalo
May 19
BUF7:00 amBuffalo
11h 01m
1 stop
SDQ6:01 pmSanto Domingo Las Americas
$451
Delta
May 12
SDQ2:00 pmSanto Domingo Las Americas
10h 19m
1 stop
BUF12:19 amBuffalo
May 19
BUF7:00 amBuffalo
11h 01m
1 stop
SDQ6:01 pmSanto Domingo Las Americas
$474

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 5/21

6:05 am-3:02 pm

1 stop8h 57m

Buffalo

Mon 6/1

7:00 am-6:01 pm

1 stop11h 01m

$401

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 5/15

7:35 pm-9:44 am

1 stop14h 09m

Buffalo

Tue 5/19

7:00 am-6:01 pm

1 stop11h 01m

$451

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 5/13

2:49 pm-11:59 pm

1 stop9h 10m

Buffalo

Tue 5/19

7:00 am-6:01 pm

1 stop11h 01m

$484

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 5/14

6:00 am-11:33 pm

1 stop17h 33m

Buffalo

Tue 5/19

6:04 am-10:46 pm

2 stops16h 42m

$490

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 6/4

9:20 am-9:05 pm

1 stop11h 45m

Buffalo

Mon 6/8

6:16 pm-8:09 am

1 stop13h 53m

$506

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 5/21

10:25 am-12:09 am

2 stops13h 44m

Buffalo

Mon 6/1

5:25 am-12:45 pm

1 stop7h 20m

$511

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 5/15

6:00 am-11:55 pm

2 stops17h 55m

Buffalo

Mon 5/18

5:55 pm-10:46 pm

2 stops28h 51m

$515

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 6/4

9:20 am-9:05 pm

1 stop11h 45m

Buffalo

Mon 6/8

6:16 pm-8:09 am

1 stop13h 53m

$517

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 5/21

6:00 am-11:59 pm

2 stops17h 59m

Buffalo

Mon 6/1

6:00 am-10:46 pm

2 stops16h 46m

$519

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 5/15

7:35 pm-9:44 am

1 stop14h 09m

Buffalo

Fri 5/22

7:39 pm-1:23 pm

1 stop17h 44m

$526

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santo Domingo to Buffalo flights?

You could potentially save up to 12% on your flight if you consider stops on a Santo Domingo to Buffalo flight.

When to book flights from Santo Domingo to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Buffalo (SDQ to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Buffalo

Fastest flight time

9h 10m

Direct flights

None
The fastest flight from Santo Domingo to Buffalo takes 9h 10m
There are no direct flights from Santo Domingo to Buffalo. There are no popular flight routes from Santo Domingo to Buffalo.
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Frequently asked questions about flying from Santo Domingo to Buffalo

  • How far is Santo Domingo Las Americas to Buffalo by plane?

    Santo Domingo Las Americas and Buffalo are 1764.1 mi apart from one another. Typically, this will take 9h 10m by plane in normal conditions.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Buffalo Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Buffalo Airport refresh daily.

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Buffalo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The required travel and health documents for your Buffalo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Buffalo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Amherst
Tonawanda
Grand Island
Williamsville
Orchard Park
Lockport
West Seneca
Bowmansville
East Aurora
Eden
Angola

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Buffalo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Buffalo from Santo Domingo.

Can I find flights from Santo Domingo to Buffalo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Buffalo from Santo Domingo which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santo Domingo to Buffalo?

momondo provides multiple filters to help you find the best flight to Buffalo from Santo Domingo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santo Domingo to Buffalo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to Buffalo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Buffalo and let you know when they change.

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