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Cheap flights from Santiago to Knoxville from $988

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Knoxville departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:45 pm - 11:12 amSCL  Santiago Arturo Merino Benitez-TYS Knoxville McGhee Tyson
14h 27m1 stop Houston George Bush Intcntl
United Airlines Logo
4:30 pm - 8:50 amTYS  Knoxville McGhee Tyson-SCL Santiago Arturo Merino Benitez
38h 20m2 stops Newark Houston George Bush Intcntl
$988United Airlines
Wed, Nov 11 - Sun, Nov 15
United Airlines Logo
10:45 pm - 11:12 amSCL  Santiago Arturo Merino Benitez-TYS Knoxville McGhee Tyson
14h 27m1 stop Houston George Bush Intcntl
United Airlines Logo
5:40 pm - 8:50 amTYS  Knoxville McGhee Tyson-SCL Santiago Arturo Merino Benitez
37h 10m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$1,008United Airlines
Wed, Nov 11 - Sun, Nov 15
United Airlines Logo
10:45 pm - 9:53 amSCL  Santiago Arturo Merino Benitez-TYS Knoxville McGhee Tyson
37h 08m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
5:40 pm - 8:50 amTYS  Knoxville McGhee Tyson-SCL Santiago Arturo Merino Benitez
37h 10m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$1,016United Airlines
Wed, Nov 11 - Sun, Nov 15
LATAM Airlines Logo
11:10 pm - 9:50 amSCL  Santiago Arturo Merino Benitez-TYS Knoxville McGhee Tyson
12h 40m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:09 pm - 7:40 amTYS  Knoxville McGhee Tyson-SCL Santiago Arturo Merino Benitez
11h 31m1 stop Atlanta Hartsfield-Jackson
$1,051LATAM Airlines
Wed, Nov 11 - Sun, Nov 15

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United Airlines flights from Santiago to Knoxville

Our best United Airlines deals on Santiago to Knoxville flight tickets
United Airlines
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
27h 14m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
Nov 15
TYS11:20 amKnoxville McGhee Tyson
43h 30m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
$988
United Airlines
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
14h 27m
1 stop
TYS11:12 amKnoxville McGhee Tyson
Nov 15
TYS5:40 pmKnoxville McGhee Tyson
37h 10m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
$1,008
United Airlines
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
37h 08m
2 stops
TYS9:53 amKnoxville McGhee Tyson
Nov 15
TYS5:40 pmKnoxville McGhee Tyson
37h 10m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
$1,016

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Santiago to Knoxville that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

SantiagoKnoxville

SCL Santiago Arturo Merino Benitez - TYS Knoxville McGhee Tyson

SCLTYS

Santiago Arturo Merino Benitez

Wed 11/11

10:45 pm-11:12 am

1 stop14h 27m

Knoxville McGhee Tyson

Sun 11/15

4:30 pm-8:50 am

2 stops38h 20m

$988

SantiagoKnoxville

SCL Santiago Arturo Merino Benitez - TYS Knoxville McGhee Tyson

SCLTYS

Santiago Arturo Merino Benitez

Wed 11/11

10:45 pm-11:12 am

1 stop14h 27m

Knoxville McGhee Tyson

Sun 11/15

5:40 pm-8:50 am

2 stops37h 10m

$1,008

SantiagoKnoxville

SCL Santiago Arturo Merino Benitez - TYS Knoxville McGhee Tyson

SCLTYS

Santiago Arturo Merino Benitez

Wed 11/11

10:45 pm-9:53 am

2 stops37h 08m

Knoxville McGhee Tyson

Sun 11/15

5:40 pm-8:50 am

2 stops37h 10m

$1,016
Quickest round-trip

SantiagoKnoxville

SCL Santiago Arturo Merino Benitez - TYS Knoxville McGhee Tyson

SCLTYS

Santiago Arturo Merino Benitez

Wed 11/11

11:10 pm-9:50 am

1 stop12h 40m

Knoxville McGhee Tyson

Sun 11/15

6:09 pm-7:40 am

1 stop11h 31m

$1,051

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Santiago to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Knoxville (SCL to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Knoxville

Fastest flight time

27h 14m

Direct flights

None
The fastest flight from Santiago to Knoxville takes 27h 14m
There are no direct flights from Santiago to Knoxville. There are no popular flight routes from Santiago to Knoxville.
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Frequently asked questions about flying from Santiago to Knoxville

  • How far is Santiago Arturo Merino Benitez to Knoxville McGhee Tyson by plane?

    The distance between Santiago Arturo Merino Benitez and Knoxville McGhee Tyson is about 4868.2 mi. By plane, this route typically takes 27h 14m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Frequently asked questions about flying from Santiago to Knoxville

  • How do I get Price Alerts for flights from Santiago to Knoxville?

    Search flight deals from Santiago to Knoxville. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Santiago to Knoxville with momondo?

    Leverage our AI within our “Price Forecast” tool, which predicts if it’s better to book now or wait until prices decrease. You can strategically pick the best days to fly and save money on your trip by using our “Price Calendar” tool. “Explore” shows an overview of how much it costs to fly to anywhere from a selected city or airport. Our “Discover” content is a great option for travel inspiration and money-saving tips, while “Price Alerts” will update you when prices change, so you can book when fares are right.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santiago to Knoxville for you.

Can I find flights from Santiago to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Santiago with this policy.

How can momondo help me find flights from Santiago to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Santiago.

I’m not ready to book a flight from Santiago to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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