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Cheap flights from Santiago to Knoxville from $951

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Knoxville departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santiago to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
8:40 pm - 7:11 pm
SCL
-
TYS
22h 31m
1 stop
LATAM Airlines Logo
2:16 pm - 8:55 pm
TYS
-
SCL
30h 39m
2 stops
$951LATAM Airlines
Fri, Aug 7 - Mon, Aug 10
Delta Logo
8:40 pm - 11:52 pm
SCL
-
TYS
27h 12m
1 stop
Delta Logo
12:01 pm - 6:55 am
TYS
-
SCL
18h 54m
2 stops
$998Delta
Sun, Aug 9 - Sun, Aug 16
LATAM Airlines Logo
8:40 pm - 12:28 pm
SCL
-
TYS
15h 48m
1 stop
LATAM Airlines Logo
2:16 pm - 7:15 am
TYS
-
SCL
16h 59m
1 stop
$1,274LATAM Airlines
Fri, Aug 7 - Mon, Aug 10

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LATAM Airlines flights from Santiago to Knoxville

Our best LATAM Airlines deals on Santiago to Knoxville flight tickets
LATAM Airlines
Aug 7
SCL8:40 pmSantiago Arturo Merino Benitez
22h 31m
1 stop
TYS7:11 pmKnoxville McGhee Tyson
Aug 10
TYS2:16 pmKnoxville McGhee Tyson
30h 39m
2 stops
SCL8:55 pmSantiago Arturo Merino Benitez
$951
LATAM Airlines
Aug 7
SCL8:40 pmSantiago Arturo Merino Benitez
15h 48m
1 stop
TYS12:28 pmKnoxville McGhee Tyson
Aug 10
TYS2:16 pmKnoxville McGhee Tyson
16h 59m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$1,274

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from Santiago to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Fri 8/7

8:40 pm-7:11 pm

1 stop22h 31m

Knoxville McGhee Tyson

Mon 8/10

2:16 pm-8:55 pm

2 stops30h 39m

$951

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Sun 8/9

8:40 pm-11:52 pm

1 stop27h 12m

Knoxville McGhee Tyson

Sun 8/16

12:01 pm-6:55 am

2 stops18h 54m

$998
Quickest round-trip

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Fri 8/7

8:40 pm-12:28 pm

1 stop15h 48m

Knoxville McGhee Tyson

Mon 8/10

2:16 pm-7:15 am

1 stop16h 59m

$1,274

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Santiago to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Knoxville (SCL to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Knoxville

Fastest flight time

12h 56m

Direct flights

None
The fastest flight from Santiago to Knoxville takes 12h 56m
There are no direct flights from Santiago to Knoxville. There are no popular flight routes from Santiago to Knoxville.
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Frequently asked questions about flying from Santiago to Knoxville

  • How far is Santiago Arturo Merino Benitez to Knoxville McGhee Tyson by plane?

    The distance between Santiago Arturo Merino Benitez and Knoxville McGhee Tyson is about 4868.2 mi. By plane, this route typically takes 12h 56m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Frequently asked questions about flying from Santiago to Knoxville

  • How do I get Price Alerts for flights from Santiago to Knoxville?

    Search flight deals from Santiago to Knoxville. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Santiago to Knoxville with momondo?

    Leverage our AI within our “Price Forecast” tool, which predicts if it’s better to book now or wait until prices decrease. You can strategically pick the best days to fly and save money on your trip by using our “Price Calendar” tool. “Explore” shows an overview of how much it costs to fly to anywhere from a selected city or airport. Our “Discover” content is a great option for travel inspiration and money-saving tips, while “Price Alerts” will update you when prices change, so you can book when fares are right.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Knoxville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santiago to Knoxville for you.

Can I find flights from Santiago to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Santiago with this policy.

How can momondo help me find flights from Santiago to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Santiago.

I’m not ready to book a flight from Santiago to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Tue 7/28
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