Cheap flights from Santiago to Chicago from $263

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Chicago departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:40 am - 8:39 am
SCL
-
ORD
34h 59m
2 stops
Multiple Airlines Logo
11:20 pm - 3:20 pm
ORD
-
SCL
14h 00m
1 stop
$515Multiple Airlines
Fri, Mar 6 - Mon, Mar 23
Multiple Airlines Logo
8:20 pm - 11:59 pm
SCL
-
ORD
28h 39m
2 stops
Multiple Airlines Logo
7:15 pm - 11:05 am
ORD
-
SCL
38h 50m
2 stops
$550Multiple Airlines
Wed, Apr 15 - Mon, Apr 20
Multiple Airlines Logo
11:25 pm - 1:41 pm
SCL
-
MDW
16h 16m
1 stop
Multiple Airlines Logo
6:30 am - 5:30 am
MDW
-
SCL
22h 00m
2 stops
$561Multiple Airlines
Wed, Mar 18 - Mon, Apr 13
LATAM Airlines Logo
10:55 pm - 5:41 pm
SCL
-
ORD
19h 46m
1 stop
LATAM Airlines Logo
2:25 pm - 6:55 am
ORD
-
SCL
15h 30m
2 stops
$563LATAM Airlines
Tue, Apr 14 - Mon, Apr 27
Multiple Airlines Logo
11:24 am - 10:36 am
SCL
-
ORD
25h 12m
2 stops
Multiple Airlines Logo
11:20 pm - 3:15 pm
ORD
-
SCL
13h 55m
1 stop
$564Multiple Airlines
Tue, Mar 24 - Mon, Mar 30
Multiple Airlines Logo
4:41 am - 9:17 pm
SCL
-
ORD
41h 36m
2 stops
Multiple Airlines Logo
11:20 pm - 2:15 pm
ORD
-
SCL
13h 55m
1 stop
$566Multiple Airlines
Wed, Apr 15 - Tue, May 5
Avianca Logo
12:30 am - 9:20 pm
SCL
-
ORD
21h 50m
1 stop
Avianca Logo
11:20 pm - 11:20 pm
ORD
-
SCL
23h 00m
1 stop
$568Avianca
Tue, May 19 - Mon, May 25
LATAM Airlines Logo
10:40 pm - 12:57 pm
SCL
-
ORD
16h 17m
1 stop
LATAM Airlines Logo
2:38 pm - 7:40 am
ORD
-
SCL
15h 02m
1 stop
$571LATAM Airlines
Thu, Mar 19 - Thu, Mar 26
Delta Logo
8:40 pm - 9:56 am
SCL
-
MDW
14h 16m
1 stop
Delta Logo
5:14 pm - 7:15 am
MDW
-
SCL
13h 01m
1 stop
$574Delta
Tue, Apr 21 - Fri, May 29
Delta Logo
11:00 pm - 4:29 pm
SCL
-
MDW
18h 29m
2 stops
Delta Logo
12:53 pm - 7:15 am
MDW
-
SCL
17h 22m
1 stop
$578Delta
Wed, Apr 15 - Tue, Apr 21

American Airlines flights from Santiago to Chicago

Our best American Airlines deals on Santiago to Chicago flight tickets
American Airlines
Apr 16
SCL8:35 pmSantiago Arturo Merino Benitez
23h 02m
1 stop
ORD6:37 pmChicago O'Hare Intl
May 3
ORD7:00 amChicago O'Hare Intl
23h 05m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
$593
American Airlines
Apr 5
SCL8:25 pmSantiago Arturo Merino Benitez
18h 51m
2 stops
ORD2:16 pmChicago O'Hare Intl
Apr 9
ORD1:54 pmChicago O'Hare Intl
16h 11m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
$594
American Airlines
Apr 16
SCL8:35 pmSantiago Arturo Merino Benitez
18h 45m
2 stops
ORD2:20 pmChicago O'Hare Intl
May 3
ORD1:54 pmChicago O'Hare Intl
16h 11m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
$598

Avianca flights from Santiago to Chicago

Our best Avianca deals on Santiago to Chicago flight tickets
Avianca
May 19
SCL12:30 amSantiago Arturo Merino Benitez
21h 50m
1 stop
ORD9:20 pmChicago O'Hare Intl
May 25
ORD11:20 pmChicago O'Hare Intl
23h 00m
1 stop
SCL11:20 pmSantiago Arturo Merino Benitez
$568
Avianca
Apr 14
SCL6:40 amSantiago Arturo Merino Benitez
15h 40m
1 stop
ORD9:20 pmChicago O'Hare Intl
Apr 27
ORD11:20 pmChicago O'Hare Intl
13h 55m
1 stop
SCL2:15 pmSantiago Arturo Merino Benitez
$573
Avianca
May 19
SCL6:40 amSantiago Arturo Merino Benitez
15h 40m
1 stop
ORD9:20 pmChicago O'Hare Intl
May 22
ORD11:20 pmChicago O'Hare Intl
13h 55m
1 stop
SCL2:15 pmSantiago Arturo Merino Benitez
$588

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Santiago to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Fri 3/6

12:40 am-8:39 am

2 stops34h 59m

Chicago O'Hare Intl

Mon 3/23

11:20 pm-3:20 pm

1 stop14h 00m

$515

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Wed 4/15

8:20 pm-11:59 pm

2 stops28h 39m

Chicago O'Hare Intl

Mon 4/20

7:15 pm-11:05 am

2 stops38h 50m

$550

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Wed 3/18

11:25 pm-1:41 pm

1 stop16h 16m

Chicago Midway

Mon 4/13

6:30 am-5:30 am

2 stops22h 00m

$561

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Tue 4/14

10:55 pm-5:41 pm

1 stop19h 46m

Chicago O'Hare Intl

Mon 4/27

2:25 pm-6:55 am

2 stops15h 30m

$563

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Tue 3/24

11:24 am-10:36 am

2 stops25h 12m

Chicago O'Hare Intl

Mon 3/30

11:20 pm-3:15 pm

1 stop13h 55m

$564

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Wed 4/15

4:41 am-9:17 pm

2 stops41h 36m

Chicago O'Hare Intl

Tue 5/5

11:20 pm-2:15 pm

1 stop13h 55m

$566

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Tue 5/19

12:30 am-9:20 pm

1 stop21h 50m

Chicago O'Hare Intl

Mon 5/25

11:20 pm-11:20 pm

1 stop23h 00m

$568

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Thu 3/19

10:40 pm-12:57 pm

1 stop16h 17m

Chicago O'Hare Intl

Thu 3/26

2:38 pm-7:40 am

1 stop15h 02m

$571

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Tue 4/21

8:40 pm-9:56 am

1 stop14h 16m

Chicago Midway

Fri 5/29

5:14 pm-7:15 am

1 stop13h 01m

$574

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Wed 4/15

11:00 pm-4:29 pm

2 stops18h 29m

Chicago Midway

Tue 4/21

12:53 pm-7:15 am

1 stop17h 22m

$578

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Santiago to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of April is, on average, the cheapest month to fly to Chicago from Santiago, with most prices found around $513. If you’re not able to fly to Chicago in April, then March is your next best option. Flight prices from Santiago to Chicago during March average around $593.

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $753 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Santiago for as low as $598 on momondo.

How have Santiago to Chicago flight prices changed over time?

As of February 2026, prices for Santiago to Chicago flights are approximately 11% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Chicago (SCL to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Chicago

Fastest flight time

13h 44m

Direct flights

None
The fastest flight from Santiago to Chicago takes 13h 44m
There are no direct flights from Santiago to Chicago. There are no popular flight routes from Santiago to Chicago.
  • How far is Santiago Arturo Merino Benitez to Chicago by plane?

    Santiago Arturo Merino Benitez and Chicago are 5311.0 mi apart from one another. By plane, this route typically takes 13h 44m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Chicago?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Chicago are updated daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Chicago?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Chicago?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to Chicago?

Best airlines flying from Santiago to Chicago

Compare and see reviews for airlines that fly from Santiago to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $267Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
AviancaPriceFrom $273Free CancellationRating
6.5
2,498 reviews
Search Avianca flights
DeltaPriceFrom $504Free CancellationRating
7.9
8,138 reviews
Search Delta flights
LATAM AirlinesPriceFrom $513Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $753Free CancellationRating
7.2
11,216 reviews
Search American Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Santiago with this policy.

How can momondo help me find flights from Santiago to Chicago?

Once you have performed a search for Santiago to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Fri 3/6
Fri 3/13

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago