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Cheap flights from Santiago to Chicago from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Chicago departing on 11/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santiago to Chicago

Cheap round-trip flights

Logo
4:25 pm - 7:41 amSCL-ORD
18h 16m2 stops
Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
$563
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Sat, Nov 8 - Wed, Nov 12
Logo
8:15 am - 11:27 amSCL-MDW
29h 12m2 stops
Logo
4:24 pm - 10:15 pmMDW-SCL
27h 51m2 stops
$612
Find Deal
Thu, Oct 9 - Mon, Oct 13
Air Canada Logo
8:35 am - 11:18 amSCL-ORD
29h 43m1 stop
Air Canada Logo
3:35 pm - 7:00 amORD-SCL
36h 25m1 stop
$663Air Canada
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Fri, Dec 19 - Fri, Feb 20
Air Canada Logo
8:35 am - 11:18 amSCL-ORD
29h 43m1 stop
Air Canada Logo
3:35 pm - 7:00 amORD-SCL
36h 25m1 stop
$664Air Canada
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Fri, Dec 19 - Fri, Feb 20
Avianca Logo
1:35 am - 9:20 pmSCL-ORD
21h 45m1 stop
Avianca Logo
10:20 pm - 3:20 pmORD-SCL
14h 00m1 stop
$673Avianca
Find Deal
Tue, Oct 28 - Thu, Nov 6
Avianca Logo
1:35 am - 9:20 pmSCL-ORD
21h 45m1 stop
Avianca Logo
10:20 pm - 12:30 amORD-SCL
23h 10m1 stop
$674Avianca
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Wed, Oct 29 - Thu, Nov 6
Delta Logo
9:40 pm - 9:40 amSCL-MDW
14h 00m1 stop
Delta Logo
10:35 am - 6:50 amMDW-SCL
18h 15m2 stops
$725Delta
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Wed, Oct 8 - Wed, Oct 15
LATAM Airlines Logo
12:10 am - 10:14 pmSCL-MDW
24h 04m2 stops
LATAM Airlines Logo
5:04 pm - 7:00 amMDW-SCL
11h 56m1 stop
$738LATAM Airlines
Find Deal
Wed, Oct 8 - Tue, Oct 14
LATAM Airlines Logo
12:10 am - 10:14 pmSCL-MDW
24h 04m2 stops
LATAM Airlines Logo
5:04 pm - 7:00 amMDW-SCL
11h 56m1 stop
$739LATAM Airlines
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Wed, Oct 8 - Tue, Oct 14
Delta Logo
11:15 pm - 12:01 pmSCL-MDW
14h 46m1 stop
Delta Logo
5:25 pm - 8:00 amMDW-SCL
12h 35m1 stop
$745Delta
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Tue, Mar 10 - Tue, Mar 31

Delta flights from Santiago to Chicago

Our best Delta deals on Santiago to Chicago flight tickets
Delta
Sep 23
SCL9:40 pmSantiago Arturo Merino Benitez
17h 21m
1 stop
ORD1:01 pmChicago O'Hare Intl
Sep 30
ORD9:50 amChicago O'Hare Intl
19h 00m
2 stops
SCL6:50 amSantiago Arturo Merino Benitez
$725
Find similar
Delta
Mar 10
SCL11:15 pmSantiago Arturo Merino Benitez
14h 46m
1 stop
MDW12:01 pmChicago Midway
Mar 31
MDW5:25 pmChicago Midway
12h 35m
1 stop
SCL8:00 amSantiago Arturo Merino Benitez
$745
Find similar
Delta
Sep 29
SCL11:55 pmSantiago Arturo Merino Benitez
18h 25m
2 stops
ORD4:20 pmChicago O'Hare Intl
Oct 10
ORD10:36 amChicago O'Hare Intl
17h 09m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
$765
Find similar

LATAM Airlines flights from Santiago to Chicago

Our best LATAM Airlines deals on Santiago to Chicago flight tickets
LATAM Airlines
Oct 8
SCL12:10 amSantiago Arturo Merino Benitez
24h 04m
2 stops
MDW10:14 pmChicago Midway
Oct 14
MDW5:04 pmChicago Midway
11h 56m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$738
Find similar
LATAM Airlines
Sep 22
SCL12:10 amSantiago Arturo Merino Benitez
20h 50m
2 stops
ORD7:00 pmChicago O'Hare Intl
Sep 30
ORD3:45 pmChicago O'Hare Intl
13h 15m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
$739
Find similar
LATAM Airlines
Sep 29
SCL11:55 pmSantiago Arturo Merino Benitez
19h 50m
1 stop
ORD5:45 pmChicago O'Hare Intl
Oct 10
ORD7:00 amChicago O'Hare Intl
20h 45m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
$741
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santiago to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Sat 11/8

4:25 pm-7:41 am

2 stops18h 16m

Chicago O'Hare Intl

Wed 11/12

10:20 pm-3:20 pm

1 stop14h 00m

$563

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Thu 10/9

8:15 am-11:27 am

2 stops29h 12m

Chicago Midway

Mon 10/13

4:24 pm-10:15 pm

2 stops27h 51m

$612

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Fri 12/19

8:35 am-11:18 am

1 stop29h 43m

Chicago O'Hare Intl

Fri 2/20

3:35 pm-7:00 am

1 stop36h 25m

$663

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Fri 12/19

8:35 am-11:18 am

1 stop29h 43m

Chicago O'Hare Intl

Fri 2/20

3:35 pm-7:00 am

1 stop36h 25m

$664

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Tue 10/28

1:35 am-9:20 pm

1 stop21h 45m

Chicago O'Hare Intl

Thu 11/6

10:20 pm-3:20 pm

1 stop14h 00m

$673

SantiagoChicago

SCL - ORD

SCLORD

Santiago Arturo Merino Benitez

Wed 10/29

1:35 am-9:20 pm

1 stop21h 45m

Chicago O'Hare Intl

Thu 11/6

10:20 pm-12:30 am

1 stop23h 10m

$674

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Wed 10/8

9:40 pm-9:40 am

1 stop14h 00m

Chicago Midway

Wed 10/15

10:35 am-6:50 am

2 stops18h 15m

$725

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Wed 10/8

12:10 am-10:14 pm

2 stops24h 04m

Chicago Midway

Tue 10/14

5:04 pm-7:00 am

1 stop11h 56m

$738

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Wed 10/8

12:10 am-10:14 pm

2 stops24h 04m

Chicago Midway

Tue 10/14

5:04 pm-7:00 am

1 stop11h 56m

$739

SantiagoChicago

SCL - MDW

SCLMDW

Santiago Arturo Merino Benitez

Tue 3/10

11:15 pm-12:01 pm

1 stop14h 46m

Chicago Midway

Tue 3/31

5:25 pm-8:00 am

1 stop12h 35m

$745

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Santiago to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of April is, on average, the cheapest month to fly to Chicago from Santiago, with most prices found around $504. If you’re not able to fly to Chicago in April, then March is your next best option. Flight prices from Santiago to Chicago during March average around $580.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Monday when prices can be found for as low as $687. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Santiago to Chicago for around $907.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the afternoon. Flights from Santiago to Chicago during this time can be as low as $749. In contrast, the most expensive time of day to depart to Chicago is in the morning when prices are around $818.

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $761 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Santiago for as low as $568 on momondo.

How have Santiago to Chicago flight prices changed over time?

As of September 2025, prices for Santiago to Chicago flights are approximately 43% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Chicago (SCL to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Chicago

Direct flights

None
There are no direct flights from Santiago to Chicago. There are no popular flight routes from Santiago to Chicago.
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  • How far is Santiago Arturo Merino Benitez to Chicago by plane?

    Santiago Arturo Merino Benitez and Chicago are 5311.0 mi apart from one another. By plane, this route typically takes 13h 30m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Chicago?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Chicago are updated daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Chicago?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Chicago?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The necessary travel and health documents for your Chicago trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to Chicago?

Best airlines flying from Santiago to Chicago

Compare and see reviews for airlines that fly from Santiago to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $501Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
DeltaPriceFrom $504Free CancellationRating
7.9
7,954 reviews
Search Delta flights
LATAM AirlinesPriceFrom $506Free CancellationRating
7.5
1,847 reviews
Search LATAM Airlines flights
AviancaPriceFrom $519Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
American AirlinesPriceFrom $753Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Lansing
Portage
Schererville
Valparaiso
Crown Point
Munster
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santiago to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from Santiago to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Santiago with this policy.

How can momondo help me find flights from Santiago to Chicago?

Once you have performed a search for Santiago to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport