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Cheap flights from Santa Fe to South Carolina from $264

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to South Carolina departing on 10/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Fe to South Carolina

Cheap round-trip flights

American Airlines Logo
6:15 am - 1:33 pmSAF-CHS
5h 18m1 stop
American Airlines Logo
7:02 am - 11:11 amCHS-SAF
6h 09m1 stop
$264American Airlines
Find Deal
mar., oct. 21 - mar., oct. 28
American Airlines Logo
7:20 pm - 6:15 amSAF-CLT
8h 55m1 stop
American Airlines Logo
5:30 am - 9:33 amCLT-SAF
6h 03m1 stop
$264American Airlines
Find Deal
jue., sep. 11 - dom., sep. 14
American Airlines Logo
6:15 am - 1:33 pmSAF-CHS
5h 18m1 stop
American Airlines Logo
12:15 pm - 10:10 pmCHS-SAF
11h 55m2 stops
$274American Airlines
Find Deal
mar., oct. 21 - mar., oct. 28
American Airlines Logo
6:15 am - 7:04 pmSAF-CHS
10h 49m2 stops
American Airlines Logo
9:42 am - 4:29 pmCHS-SAF
8h 47m2 stops
$279American Airlines
Find Deal
mar., oct. 21 - mar., oct. 28
American Airlines Logo
6:15 am - 3:52 pmSAF-SAV
7h 37m1 stop
American Airlines Logo
4:23 pm - 9:59 pmSAV-SAF
7h 36m1 stop
$286American Airlines
Find Deal
vie., ago. 22 - mar., ago. 26
American Airlines Logo
7:15 am - 3:52 pmSAF-SAV
6h 37m1 stop
American Airlines Logo
7:28 am - 1:34 pmSAV-SAF
8h 06m2 stops
$296American Airlines
Find Deal
vie., ago. 22 - mar., ago. 26
American Airlines Logo
2:04 pm - 11:59 pmSAF-SAV
7h 55m2 stops
American Airlines Logo
7:28 am - 1:34 pmSAV-SAF
8h 06m2 stops
$301American Airlines
Find Deal
vie., ago. 22 - mar., ago. 26
American Airlines Logo
2:04 pm - 10:02 pmSAF-CHS
5h 58m1 stop
American Airlines Logo
2:40 pm - 8:47 pmCHS-SAF
8h 07m1 stop
$314American Airlines
Find Deal
vie., ago. 22 - mar., ago. 26
United Airlines Logo
7:00 am - 5:15 pmSAF-CLT
8h 15m2 stops
United Airlines Logo
6:40 am - 5:09 pmCLT-SAF
12h 29m2 stops
$464United Airlines
Find Deal
sáb., ago. 23 - mié., ago. 27
United Airlines Logo
7:00 am - 9:37 pmSAF-CLT
12h 37m2 stops
United Airlines Logo
10:35 am - 10:00 pmCLT-SAF
13h 25m2 stops
$469United Airlines
Find Deal
sáb., ago. 23 - mar., ago. 26

United Airlines flights from Santa Fe to South Carolina

Our best United Airlines deals on Santa Fe to South Carolina flight tickets
United Airlines
Aug 23
SAF7:00 amSanta Fe
8h 15m
2 stops
CLT5:15 pmCharlotte Douglas
Aug 27
CLT6:40 amCharlotte Douglas
12h 29m
2 stops
SAF5:09 pmSanta Fe
$464
Find similar
United Airlines
Aug 23
SAF7:00 amSanta Fe
12h 37m
2 stops
CLT9:37 pmCharlotte Douglas
Aug 26
CLT10:35 amCharlotte Douglas
13h 25m
2 stops
SAF10:00 pmSanta Fe
$469
Find similar
United Airlines
Sep 11
SAF5:59 pmSanta Fe
26h 54m
1 stop
CLT10:53 pmCharlotte Douglas
Sep 14
CLT6:40 amCharlotte Douglas
28h 43m
2 stops
SAF9:23 amSanta Fe
$520
Find similar

American Airlines flights from Santa Fe to South Carolina

Our best American Airlines deals on Santa Fe to South Carolina flight tickets
American Airlines
Sep 11
SAF7:20 pmSanta Fe
8h 55m
1 stop
CLT6:15 amCharlotte Douglas
Sep 14
CLT5:30 amCharlotte Douglas
6h 03m
1 stop
SAF9:33 amSanta Fe
$264
Find similar
American Airlines
Oct 21
SAF6:15 amSanta Fe
5h 18m
1 stop
CHS1:33 pmCharleston
Oct 28
CHS12:15 pmCharleston
11h 55m
2 stops
SAF10:10 pmSanta Fe
$274
Find similar
American Airlines
Oct 21
SAF6:15 amSanta Fe
10h 49m
2 stops
CHS7:04 pmCharleston
Oct 28
CHS9:42 amCharleston
8h 47m
2 stops
SAF4:29 pmSanta Fe
$279
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 7, 2025.
Use the filters below to find and compare flights from Santa Fe to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

mar. 10/21

6:15 am-1:33 pm

1 stop5h 18m

Charleston

mar. 10/28

7:02 am-11:11 am

1 stop6h 09m

$264

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

jue. 9/11

7:20 pm-6:15 am

1 stop8h 55m

Charlotte Douglas

dom. 9/14

5:30 am-9:33 am

1 stop6h 03m

$264

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

mar. 10/21

6:15 am-1:33 pm

1 stop5h 18m

Charleston

mar. 10/28

12:15 pm-10:10 pm

2 stops11h 55m

$274

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

mar. 10/21

6:15 am-7:04 pm

2 stops10h 49m

Charleston

mar. 10/28

9:42 am-4:29 pm

2 stops8h 47m

$279

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

vie. 8/22

6:15 am-3:52 pm

1 stop7h 37m

Savannah/Hilton Head

mar. 8/26

4:23 pm-9:59 pm

1 stop7h 36m

$286

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

vie. 8/22

7:15 am-3:52 pm

1 stop6h 37m

Savannah/Hilton Head

mar. 8/26

7:28 am-1:34 pm

2 stops8h 06m

$296

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

vie. 8/22

2:04 pm-11:59 pm

2 stops7h 55m

Savannah/Hilton Head

mar. 8/26

7:28 am-1:34 pm

2 stops8h 06m

$301

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

vie. 8/22

2:04 pm-10:02 pm

1 stop5h 58m

Charleston

mar. 8/26

2:40 pm-8:47 pm

1 stop8h 07m

$314

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

sáb. 8/23

7:00 am-5:15 pm

2 stops8h 15m

Charlotte Douglas

mié. 8/27

6:40 am-5:09 pm

2 stops12h 29m

$464

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

sáb. 8/23

7:00 am-9:37 pm

2 stops12h 37m

Charlotte Douglas

mar. 8/26

10:35 am-10:00 pm

2 stops13h 25m

$469

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Santa Fe to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Thursday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $388. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $571.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Santa Fe to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $480. Try not to purchase tickets in the afternoon because they tend to be around $606. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Santa Fe to South Carolina flights?

You could potentially save up to 53% on your flight if you consider stops on a Santa Fe to South Carolina flight.

Cheap Santa Fe to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to South Carolina

Best Price Found

$290

Fastest flight time

4h 58m

Direct flights

None

Airports in South Carolina

4 airports
The best one-way flight to South Carolina from Santa Fe in the past 72 hours is $290. The best round-trip flight deal from Santa Fe to South Carolina found on momondo in the last 72 hours is $264.
The fastest flight from Santa Fe to South Carolina takes 4h 58m
There are no direct flights from Santa Fe to South Carolina. Popular non-direct routes for this connection are Santa Fe Airport - Charleston Airport, Santa Fe Airport - Greenville Airport and Santa Fe Airport - Charlotte Douglas Airport.
There are 4 airports near South Carolina: Greenville (GSP), Savannah/Hilton Head (SAV), Charlotte Douglas (CLT), Charleston (CHS)
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  • When did momondo last update prices for flights from Santa Fe Airport to South Carolina?

    Prices for flights from Santa Fe Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Fe Airport to South Carolina?

  • How old do you have to be to fly from Santa Fe Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Fe to South Carolina

Compare and see reviews for airlines that fly from Santa Fe to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $223Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Fe to South Carolina for you.

Can I find flights from Santa Fe to South Carolina with flexible booking policies on momondo?

All flight searches from Santa Fe to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Fe to South Carolina?

Once all potential Santa Fe to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Santa Fe are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

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