Cheap flights from Santa Fe to South Carolina from $329

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to South Carolina departing on 4/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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American Airlines Logo
5:13 pm - 12:53 am
SAF
-
CLT
5h 40m
1 stop
American Airlines Logo
5:45 am - 9:38 am
CLT
-
SAF
5h 53m
1 stop
$344American Airlines
Thu, Jun 18 - Tue, Jun 23
American Airlines Logo
5:13 pm - 12:53 am
SAF
-
CLT
5h 40m
1 stop
American Airlines Logo
3:25 pm - 10:42 pm
CLT
-
SAF
9h 17m
1 stop
$399American Airlines
Thu, Jun 18 - Tue, Jun 23
United Airlines Logo
7:00 am - 2:57 pm
SAF
-
SAV
5h 57m
1 stop
United Airlines Logo
4:05 pm - 8:43 pm
SAV
-
SAF
6h 38m
1 stop
$413United Airlines
Sat, Aug 15 - Sat, Aug 22
United Airlines Logo
7:00 am - 2:57 pm
SAF
-
SAV
5h 57m
1 stop
United Airlines Logo
9:50 am - 8:43 pm
SAV
-
SAF
12h 53m
2 stops
$422United Airlines
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
2:04 pm - 12:24 am
SAF
-
CHS
8h 20m
2 stops
American Airlines Logo
4:51 pm - 9:07 pm
CHS
-
SAF
6h 16m
1 stop
$445American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
2:04 pm - 12:24 am
SAF
-
CHS
8h 20m
2 stops
American Airlines Logo
6:35 am - 2:55 pm
CHS
-
SAF
10h 20m
2 stops
$507American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
7:30 am - 7:52 pm
SAF
-
SAV
10h 22m
2 stops
American Airlines Logo
9:40 am - 7:01 pm
SAV
-
SAF
11h 21m
2 stops
$519American Airlines
Sat, Aug 15 - Sat, Aug 22
American Airlines Logo
2:04 pm - 10:41 pm
SAF
-
CHS
6h 37m
1 stop
American Airlines Logo
4:51 pm - 9:07 pm
CHS
-
SAF
6h 16m
1 stop
$526American Airlines
Wed, Apr 29 - Sat, May 2
American Airlines Logo
12:36 pm - 10:31 pm
SAF
-
SAV
7h 55m
1 stop
American Airlines Logo
4:11 pm - 9:07 pm
SAV
-
SAF
6h 56m
1 stop
$560American Airlines
Thu, Apr 9 - Mon, Apr 13
American Airlines Logo
6:05 am - 1:43 pm
SAF
-
SAV
5h 38m
1 stop
American Airlines Logo
7:02 am - 12:25 pm
SAV
-
SAF
7h 23m
1 stop
$648American Airlines
Thu, Jun 4 - Tue, Jun 9

American Airlines flights from Santa Fe to South Carolina

Our best American Airlines deals on Santa Fe to South Carolina flight tickets
American Airlines
Jun 18
SAF5:13 pmSanta Fe
5h 40m
1 stop
CLT12:53 amCharlotte Douglas
Jun 23
CLT5:45 amCharlotte Douglas
5h 53m
1 stop
SAF9:38 amSanta Fe
$344
American Airlines
Jun 18
SAF5:13 pmSanta Fe
5h 40m
1 stop
CLT12:53 amCharlotte Douglas
Jun 23
CLT3:25 pmCharlotte Douglas
9h 17m
1 stop
SAF10:42 pmSanta Fe
$399
American Airlines
Apr 29
SAF2:04 pmSanta Fe
8h 20m
2 stops
CHS12:24 amCharleston
May 2
CHS4:51 pmCharleston
6h 16m
1 stop
SAF9:07 pmSanta Fe
$445

United Airlines flights from Santa Fe to South Carolina

Our best United Airlines deals on Santa Fe to South Carolina flight tickets
United Airlines
Aug 15
SAF7:00 amSanta Fe
5h 57m
1 stop
SAV2:57 pmSavannah/Hilton Head
Aug 22
SAV4:05 pmSavannah/Hilton Head
6h 38m
1 stop
SAF8:43 pmSanta Fe
$413
United Airlines
Aug 15
SAF7:00 amSanta Fe
5h 57m
1 stop
SAV2:57 pmSavannah/Hilton Head
Aug 22
SAV9:50 amSavannah/Hilton Head
12h 53m
2 stops
SAF8:43 pmSanta Fe
$422
United Airlines
Jun 18
SAF1:22 pmSanta Fe
7h 46m
1 stop
CLT11:08 pmCharlotte Douglas
Jun 23
CLT7:44 pmCharlotte Douglas
16h 00m
2 stops
SAF9:44 amSanta Fe
$662

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Santa Fe to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Thu 6/18

5:13 pm-12:53 am

1 stop5h 40m

Charlotte Douglas

Tue 6/23

5:45 am-9:38 am

1 stop5h 53m

$344

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Thu 6/18

5:13 pm-12:53 am

1 stop5h 40m

Charlotte Douglas

Tue 6/23

3:25 pm-10:42 pm

1 stop9h 17m

$399

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Sat 8/15

7:00 am-2:57 pm

1 stop5h 57m

Savannah/Hilton Head

Sat 8/22

4:05 pm-8:43 pm

1 stop6h 38m

$413

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Sat 8/15

7:00 am-2:57 pm

1 stop5h 57m

Savannah/Hilton Head

Sat 8/22

9:50 am-8:43 pm

2 stops12h 53m

$422

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Wed 4/29

2:04 pm-12:24 am

2 stops8h 20m

Charleston

Sat 5/2

4:51 pm-9:07 pm

1 stop6h 16m

$445

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Wed 4/29

2:04 pm-12:24 am

2 stops8h 20m

Charleston

Sat 5/2

6:35 am-2:55 pm

2 stops10h 20m

$507

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Sat 8/15

7:30 am-7:52 pm

2 stops10h 22m

Savannah/Hilton Head

Sat 8/22

9:40 am-7:01 pm

2 stops11h 21m

$519

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Wed 4/29

2:04 pm-10:41 pm

1 stop6h 37m

Charleston

Sat 5/2

4:51 pm-9:07 pm

1 stop6h 16m

$526

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Thu 4/9

12:36 pm-10:31 pm

1 stop7h 55m

Savannah/Hilton Head

Mon 4/13

4:11 pm-9:07 pm

1 stop6h 56m

$560

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Thu 6/4

6:05 am-1:43 pm

1 stop5h 38m

Savannah/Hilton Head

Tue 6/9

7:02 am-12:25 pm

1 stop7h 23m

$648

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Santa Fe to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Fe to South Carolina flights?

You could potentially save up to 42% on your flight if you consider stops on a Santa Fe to South Carolina flight.

Cheap Santa Fe to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to South Carolina

Fastest flight time

5h 57m

Direct flights

None
The fastest flight from Santa Fe to South Carolina takes 5h 57m
There are no direct flights from Santa Fe to South Carolina. There are no popular flight routes from Santa Fe to South Carolina.
  • When did momondo last update prices for flights from Santa Fe Airport to South Carolina?

    Prices for flights from Santa Fe Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Fe Airport to South Carolina?

  • How old do you have to be to fly from Santa Fe Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Fe to South Carolina

Compare and see reviews for airlines that fly from Santa Fe to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $374Free CancellationRating
7.1
11,531 reviews
Search American Airlines flights

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Why should I use momondo to find a flight deal from Santa Fe to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Fe to South Carolina for you.

Can I find flights from Santa Fe to South Carolina with flexible booking policies on momondo?

All flight searches from Santa Fe to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Fe to South Carolina?

Once all potential Santa Fe to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to South Carolina right now. Can momondo alert me if prices change?

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1 adult
Wed 4/29
Wed 5/6

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