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Cheap flights from Santa Fe to South Carolina from $239

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to South Carolina departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Fe to South Carolina

Cheap round-trip flights

American Airlines Logo
2:07 pm - 11:49 pmSAF-CHS
7h 42m1 stop
American Airlines Logo
12:15 pm - 9:01 pmCHS-SAF
10h 46m2 stops
$325American Airlines
Find Deal
Tue, Oct 21 - Tue, Oct 28
American Airlines Logo
2:07 pm - 11:59 pmSAF-CHS
7h 52m2 stops
American Airlines Logo
9:42 am - 4:29 pmCHS-SAF
8h 47m2 stops
$330American Airlines
Find Deal
Tue, Oct 21 - Tue, Oct 28
American Airlines Logo
2:07 pm - 11:49 pmSAF-CHS
7h 42m1 stop
American Airlines Logo
2:26 pm - 9:01 pmCHS-SAF
8h 35m1 stop
$365American Airlines
Find Deal
Tue, Oct 21 - Tue, Oct 28
American Airlines Logo
12:58 pm - 9:55 pmSAF-CHS
6h 57m1 stop
American Airlines Logo
5:31 am - 3:47 pmCHS-SAF
12h 16m2 stops
$404American Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 25
American Airlines Logo
7:20 pm - 8:32 amSAF-CHS
11h 12m2 stops
American Airlines Logo
5:31 am - 3:47 pmCHS-SAF
12h 16m2 stops
$409American Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 25
American Airlines Logo
6:15 am - 6:33 pmSAF-HHH
10h 18m2 stops
American Airlines Logo
11:47 am - 9:48 pmHHH-SAF
12h 01m2 stops
$444American Airlines
Find Deal
Wed, Dec 10 - Sat, Dec 13
American Airlines Logo
7:22 pm - 10:17 amSAF-CHS
12h 55m2 stops
American Airlines Logo
3:55 pm - 8:00 pmCHS-SAF
6h 05m1 stop
$445American Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
10:45 am - 11:25 pmSAF-CHS
10h 40m2 stops
United Airlines Logo
10:59 am - 9:54 pmCHS-SAF
12h 55m2 stops
$459United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
7:00 am - 9:55 pmSAF-SAV
12h 55m2 stops
United Airlines Logo
7:17 pm - 8:32 amSAV-SAF
15h 15m2 stops
$468United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
American Airlines Logo
10:44 am - 5:45 pmSAF-CHS
5h 01m1 stop
American Airlines Logo
7:14 am - 11:07 amCHS-SAF
5h 53m1 stop
$476American Airlines
Find Deal
Wed, Mar 11 - Wed, Mar 25

American Airlines flights from Santa Fe to South Carolina

Our best American Airlines deals on Santa Fe to South Carolina flight tickets
American Airlines
Oct 21
SAF2:07 pmSanta Fe
7h 42m
1 stop
CHS11:49 pmCharleston
Oct 28
CHS12:15 pmCharleston
10h 46m
2 stops
SAF9:01 pmSanta Fe
$325
Find similar
American Airlines
Oct 21
SAF2:07 pmSanta Fe
7h 52m
2 stops
CHS11:59 pmCharleston
Oct 28
CHS9:42 amCharleston
8h 47m
2 stops
SAF4:29 pmSanta Fe
$330
Find similar
American Airlines
Oct 21
SAF2:07 pmSanta Fe
7h 42m
1 stop
CHS11:49 pmCharleston
Oct 28
CHS2:26 pmCharleston
8h 35m
1 stop
SAF9:01 pmSanta Fe
$365
Find similar

United Airlines flights from Santa Fe to South Carolina

Our best United Airlines deals on Santa Fe to South Carolina flight tickets
United Airlines
Mar 3
SAF10:45 amSanta Fe
10h 40m
2 stops
CHS11:25 pmCharleston
Mar 7
CHS10:59 amCharleston
12h 55m
2 stops
SAF9:54 pmSanta Fe
$459
Find similar
United Airlines
Mar 3
SAF7:00 amSanta Fe
12h 55m
2 stops
SAV9:55 pmSavannah/Hilton Head
Mar 7
SAV7:17 pmSavannah/Hilton Head
15h 15m
2 stops
SAF8:32 amSanta Fe
$468
Find similar
United Airlines
Mar 3
SAF7:00 amSanta Fe
9h 52m
2 stops
SAV6:52 pmSavannah/Hilton Head
Mar 7
SAV7:17 pmSavannah/Hilton Head
15h 15m
2 stops
SAF8:32 amSanta Fe
$514
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from Santa Fe to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 10/21

2:07 pm-11:49 pm

1 stop7h 42m

Charleston

Tue 10/28

12:15 pm-9:01 pm

2 stops10h 46m

$325

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 10/21

2:07 pm-11:59 pm

2 stops7h 52m

Charleston

Tue 10/28

9:42 am-4:29 pm

2 stops8h 47m

$330

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 10/21

2:07 pm-11:49 pm

1 stop7h 42m

Charleston

Tue 10/28

2:26 pm-9:01 pm

1 stop8h 35m

$365

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 3/10

12:58 pm-9:55 pm

1 stop6h 57m

Charleston

Wed 3/25

5:31 am-3:47 pm

2 stops12h 16m

$404

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 3/10

7:20 pm-8:32 am

2 stops11h 12m

Charleston

Wed 3/25

5:31 am-3:47 pm

2 stops12h 16m

$409

Santa FeHilton Head Island

SAF - HHH

SAFHHH

Santa Fe

Wed 12/10

6:15 am-6:33 pm

2 stops10h 18m

Hilton Head Island

Sat 12/13

11:47 am-9:48 pm

2 stops12h 01m

$444

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 3/3

7:22 pm-10:17 am

2 stops12h 55m

Charleston

Sat 3/7

3:55 pm-8:00 pm

1 stop6h 05m

$445

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Tue 3/3

10:45 am-11:25 pm

2 stops10h 40m

Charleston

Sat 3/7

10:59 am-9:54 pm

2 stops12h 55m

$459

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Tue 3/3

7:00 am-9:55 pm

2 stops12h 55m

Savannah/Hilton Head

Sat 3/7

7:17 pm-8:32 am

2 stops15h 15m

$468

Santa FeCharleston

SAF - CHS

SAFCHS

Santa Fe

Wed 3/11

10:44 am-5:45 pm

1 stop5h 01m

Charleston

Wed 3/25

7:14 am-11:07 am

1 stop5h 53m

$476

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Santa Fe to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Thursday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $388. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $571.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Santa Fe to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $480. Try not to purchase tickets in the afternoon because they tend to be around $606. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Santa Fe to South Carolina flights?

You could potentially save up to 29% on your flight if you consider stops on a Santa Fe to South Carolina flight.

Cheap Santa Fe to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to South Carolina

Direct flights

None
There are no direct flights from Santa Fe to South Carolina. There are no popular flight routes from Santa Fe to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Santa Fe Airport to South Carolina?

    Prices for flights from Santa Fe Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Fe Airport to South Carolina?

  • How old do you have to be to fly from Santa Fe Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Fe to South Carolina

Compare and see reviews for airlines that fly from Santa Fe to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $374Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Fe to South Carolina for you.

Can I find flights from Santa Fe to South Carolina with flexible booking policies on momondo?

All flight searches from Santa Fe to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Fe to South Carolina?

Once all potential Santa Fe to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Santa Fe are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Sat 10/25
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