Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Santa Fe to South Carolina from $339

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to South Carolina departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Santa Fe to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:16 pm - 10:59 pm
SAF
-
CLT
7h 43m1 stop
United Airlines Logo
8:00 am - 12:39 pm
CLT
-
SAF
6h 39m1 stop
$379United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
10:45 am - 11:48 pm
SAF
-
GSP
11h 03m2 stops
United Airlines Logo
10:00 am - 8:47 pm
GSP
-
SAF
12h 47m2 stops
$379United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
1:16 pm - 10:59 pm
SAF
-
CLT
7h 43m1 stop
United Airlines Logo
6:10 am - 2:54 pm
CLT
-
SAF
10h 44m2 stops
$389United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
10:45 am - 10:46 pm
SAF
-
SAV
10h 01m2 stops
United Airlines Logo
3:54 pm - 8:47 pm
SAV
-
SAF
6h 53m1 stop
$389United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
10:45 am - 10:46 pm
SAF
-
SAV
10h 01m2 stops
United Airlines Logo
10:10 am - 8:47 pm
SAV
-
SAF
12h 37m2 stops
$394United Airlines
Sat, Jan 24 - Wed, Jan 28
United Airlines Logo
7:00 am - 8:47 pm
SAF
-
GSP
11h 47m2 stops
United Airlines Logo
6:35 am - 2:54 pm
GSP
-
SAF
10h 19m2 stops
$394United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
3:30 pm - 10:59 pm
SAF
-
CLT
5h 29m1 stop
United Airlines Logo
11:00 am - 8:47 pm
CLT
-
SAF
11h 47m2 stops
$399United Airlines
Sat, Jan 31 - Wed, Feb 4
United Airlines Logo
7:00 am - 9:36 pm
SAF
-
SAV
12h 36m2 stops
United Airlines Logo
3:54 pm - 8:47 pm
SAV
-
SAF
6h 53m1 stop
$399United Airlines
Sat, Jan 24 - Wed, Jan 28
American Airlines Logo
4:43 pm - 12:15 am
SAF
-
CLT
5h 32m1 stop
American Airlines Logo
3:06 pm - 9:58 pm
CLT
-
SAF
8h 52m1 stop
$592American Airlines
Mon, Dec 22 - Mon, Dec 29
American Airlines Logo
10:05 am - 7:21 pm
SAF
-
CLT
7h 16m1 stop
American Airlines Logo
11:04 am - 6:10 pm
CLT
-
SAF
9h 06m1 stop
$838American Airlines
Tue, Dec 23 - Sun, Dec 28

American Airlines flights from Santa Fe to South Carolina

Our best American Airlines deals on Santa Fe to South Carolina flight tickets
American Airlines
Dec 22
SAF4:43 pmSanta Fe
5h 32m
1 stop
CLT12:15 amCharlotte Douglas
Dec 29
CLT3:06 pmCharlotte Douglas
8h 52m
1 stop
SAF9:58 pmSanta Fe
$592
Find similar
American Airlines
Dec 23
SAF10:05 amSanta Fe
7h 16m
1 stop
CLT7:21 pmCharlotte Douglas
Dec 28
CLT11:04 amCharlotte Douglas
9h 06m
1 stop
SAF6:10 pmSanta Fe
$838
Find similar
American Airlines
Dec 22
SAF4:43 pmSanta Fe
5h 32m
1 stop
CLT12:15 amCharlotte Douglas
Dec 29
CLT3:41 pmCharlotte Douglas
8h 17m
2 stops
SAF9:58 pmSanta Fe
$889
Find similar

United Airlines flights from Santa Fe to South Carolina

Our best United Airlines deals on Santa Fe to South Carolina flight tickets
United Airlines
Jan 10
SAF1:16 pmSanta Fe
7h 43m
1 stop
CLT10:59 pmCharlotte Douglas
Jan 13
CLT8:00 amCharlotte Douglas
6h 39m
1 stop
SAF12:39 pmSanta Fe
$379
Find similar
United Airlines
Jan 10
SAF1:16 pmSanta Fe
7h 43m
1 stop
CLT10:59 pmCharlotte Douglas
Jan 13
CLT6:10 amCharlotte Douglas
10h 44m
2 stops
SAF2:54 pmSanta Fe
$389
Find similar
United Airlines
Jan 24
SAF10:45 amSanta Fe
10h 01m
2 stops
SAV10:46 pmSavannah/Hilton Head
Jan 28
SAV10:10 amSavannah/Hilton Head
12h 37m
2 stops
SAF8:47 pmSanta Fe
$394
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Santa Fe to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Sat 1/10

1:16 pm-10:59 pm

1 stop7h 43m

Charlotte Douglas

Tue 1/13

8:00 am-12:39 pm

1 stop6h 39m

$379

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Sat 1/17

10:45 am-11:48 pm

2 stops11h 03m

Greenville

Wed 1/21

10:00 am-8:47 pm

2 stops12h 47m

$379

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Sat 1/10

1:16 pm-10:59 pm

1 stop7h 43m

Charlotte Douglas

Tue 1/13

6:10 am-2:54 pm

2 stops10h 44m

$389

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Sat 1/24

10:45 am-10:46 pm

2 stops10h 01m

Savannah/Hilton Head

Wed 1/28

3:54 pm-8:47 pm

1 stop6h 53m

$389

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Sat 1/24

10:45 am-10:46 pm

2 stops10h 01m

Savannah/Hilton Head

Wed 1/28

10:10 am-8:47 pm

2 stops12h 37m

$394

Santa FeGreenville

SAF - GSP

SAFGSP

Santa Fe

Sat 1/17

7:00 am-8:47 pm

2 stops11h 47m

Greenville

Wed 1/21

6:35 am-2:54 pm

2 stops10h 19m

$394

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Sat 1/31

3:30 pm-10:59 pm

1 stop5h 29m

Charlotte Douglas

Wed 2/4

11:00 am-8:47 pm

2 stops11h 47m

$399

Santa FeSavannah

SAF - SAV

SAFSAV

Santa Fe

Sat 1/24

7:00 am-9:36 pm

2 stops12h 36m

Savannah/Hilton Head

Wed 1/28

3:54 pm-8:47 pm

1 stop6h 53m

$399

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Mon 12/22

4:43 pm-12:15 am

1 stop5h 32m

Charlotte Douglas

Mon 12/29

3:06 pm-9:58 pm

1 stop8h 52m

$592

Santa FeCharlotte

SAF - CLT

SAFCLT

Santa Fe

Tue 12/23

10:05 am-7:21 pm

1 stop7h 16m

Charlotte Douglas

Sun 12/28

11:04 am-6:10 pm

1 stop9h 06m

$838

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to South Carolina from

How to get the cheapest flight ticket from Santa Fe to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Thursday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $388. The most expensive day to fly to South Carolina is Friday, with ticket prices averaging around $571.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Santa Fe to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $480. Try not to purchase tickets in the afternoon because they tend to be around $606. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Santa Fe to South Carolina flights?

You could potentially save up to 42% on your flight if you consider stops on a Santa Fe to South Carolina flight.

Cheap Santa Fe to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to South Carolina

Fastest flight time

5h 29m

Direct flights

None
The fastest flight from Santa Fe to South Carolina takes 5h 29m
There are no direct flights from Santa Fe to South Carolina. There are no popular flight routes from Santa Fe to South Carolina.
Search flight deals

  • When did momondo last update prices for flights from Santa Fe Airport to South Carolina?

    Prices for flights from Santa Fe Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Fe Airport to South Carolina?

  • How old do you have to be to fly from Santa Fe Airport to South Carolina?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Fe to South Carolina

Compare and see reviews for airlines that fly from Santa Fe to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $264Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Fe to South Carolina for you.

Can I find flights from Santa Fe to South Carolina with flexible booking policies on momondo?

All flight searches from Santa Fe to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Fe to South Carolina?

Once all potential Santa Fe to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Santa Fe are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/10
Sat 1/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo
Flights to New Yorkfrom $34
Flights to Los Angelesfrom $49
Flights to Miamifrom $49
Flights to Chicagofrom $49
Flights to Orlandofrom $41
Flights to San Franciscofrom $53
Flights to Las Vegasfrom $40
Flights to Washington, D.C.from $49
Flights to Bostonfrom $55
Flights to Atlantafrom $49
Flights to Dallasfrom $52
Flights to Seattlefrom $58