What is the cheapest airline that flies from Santa Fe to South Carolina?

American Airlines is the most popular carrier operating from Santa Fe to South Carolina

What airlines fly to South Carolina?

Delta, American Airlines and Southwest are the top three most popular airlines that fly to South Carolina from Santa Fe according to our data. Delta is the first choice among our users, with 40% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 3 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Santa Fe Airport to South Carolina?

Prices for flights from Santa Fe Airport to South Carolina are refreshed on a daily basis.

How many operators does momondo search for flights from Santa Fe Airport to South Carolina?

There is 1 operator available for flights from Santa Fe Airport to South Carolina as of October 2026.

How old do you have to be to fly from Santa Fe Airport to South Carolina?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$467 Cheap Flights from Santa Fe to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santa Fe to South Carolina

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 2:57 pmSAF Santa Fe-CHS Charleston

5h 57m1 stop Denver Intl

4:00 pm - 8:51 pmCHS Charleston-SAF Santa Fe

6h 51m1 stop Denver Intl

$467United Airlines

Wed, Jan 6 - Sat, Jan 9

7:00 am - 3:00 pmSAF Santa Fe-CHS Charleston

6h 00m1 stop Denver Intl

4:02 pm - 8:33 pmCHS Charleston-SAF Santa Fe

6h 31m1 stop Denver Intl

$467United Airlines

Wed, Jan 6 - Sat, Jan 9

7:00 am - 3:00 pmSAF Santa Fe-CHS Charleston

6h 00m1 stop Denver Intl

6:00 am - 5:11 pmCHS Charleston-SAF Santa Fe

13h 11m2 stops Chicago O'Hare Intl Denver Intl

$473United Airlines

Wed, Jan 6 - Sat, Jan 9

7:00 am - 3:00 pmSAF Santa Fe-CHS Charleston

6h 00m1 stop Denver Intl

6:00 am - 5:11 pmCHS Charleston-SAF Santa Fe

13h 11m2 stops Newark Denver Intl

$473United Airlines

Wed, Jan 6 - Sat, Jan 9

7:00 am - 11:19 pmSAF Santa Fe-CHS Charleston

14h 19m2 stops Denver Intl Newark

4:00 pm - 8:51 pmCHS Charleston-SAF Santa Fe

6h 51m1 stop Denver Intl

$563United Airlines

Wed, Jan 6 - Sat, Jan 9

3:11 pm - 10:52 pmSAF Santa Fe-MYR Myrtle Beach Intl

5h 41m1 stop Dallas/Fort Worth

4:57 pm - 9:55 pmMYR Myrtle Beach Intl-SAF Santa Fe

6h 58m1 stop Dallas/Fort Worth

$588American Airlines

Wed, Oct 21 - Thu, Oct 29

3:11 pm - 10:52 pmSAF Santa Fe-MYR Myrtle Beach Intl

5h 41m1 stop Dallas/Fort Worth

5:00 am - 2:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

11h 41m2 stops Charlotte Douglas Dallas/Fort Worth

$594American Airlines

Wed, Oct 21 - Thu, Oct 29

7:15 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

11h 22m2 stops Phoenix Sky Harbor Intl Charlotte Douglas

2:11 pm - 9:55 pmMYR Myrtle Beach Intl-SAF Santa Fe

9h 44m2 stops Charlotte Douglas Dallas/Fort Worth

$599American Airlines

Wed, Oct 21 - Thu, Oct 29

10:45 am - 3:13 pmSAF Santa Fe-CHS Charleston

26h 28m2 stops Denver Intl Washington, D.C. Dulles Intl

4:02 pm - 8:33 pmCHS Charleston-SAF Santa Fe

6h 31m1 stop Denver Intl

$616United Airlines

Wed, Jan 6 - Sat, Jan 9

7:00 am - 3:03 pmSAF Santa Fe-GSP Greenville

6h 03m1 stop Denver Intl

6:20 am - 5:10 pmGSP Greenville-SAF Santa Fe

12h 50m2 stops Chicago O'Hare Intl Denver Intl

$618United Airlines

Sat, Oct 31 - Wed, Nov 4

Cheap last minute flights

Enter your travel dates to find the best prices.

7:15 pm - 11:13 amSAF Santa Fe-MYR Myrtle Beach Intl

13h 58m2 stops Phoenix Sky Harbor Intl Charlotte Douglas

7:00 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

8h 41m1 stop Dallas/Fort Worth

$761American Airlines

Fri, Oct 9 - Sun, Oct 11

6:08 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

12h 29m2 stops Los Angeles Charlotte Douglas

7:00 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

8h 41m1 stop Dallas/Fort Worth

$761American Airlines

Fri, Oct 9 - Sun, Oct 11

6:08 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

12h 29m2 stops Los Angeles Charlotte Douglas

7:00 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

8h 41m1 stop Dallas/Fort Worth

$792American Airlines

Fri, Oct 9 - Sun, Oct 11

6:08 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

12h 29m2 stops Los Angeles Charlotte Douglas

7:00 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

8h 41m1 stop Dallas/Fort Worth

$826American Airlines

Fri, Oct 9 - Sun, Oct 11

6:08 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

12h 29m2 stops Los Angeles Charlotte Douglas

6:30 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

9h 11m2 stops Charlotte Douglas Dallas/Fort Worth

$831American Airlines

Fri, Oct 9 - Sun, Oct 11

12:36 pm - 10:52 pmSAF Santa Fe-MYR Myrtle Beach Intl

8h 16m1 stop Dallas/Fort Worth

7:00 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

8h 41m1 stop Dallas/Fort Worth

$851American Airlines

Fri, Oct 9 - Sun, Oct 11

12:36 pm - 10:52 pmSAF Santa Fe-MYR Myrtle Beach Intl

8h 16m1 stop Dallas/Fort Worth

7:00 am - 1:41 pmMYR Myrtle Beach Intl-SAF Santa Fe

8h 41m1 stop Dallas/Fort Worth

$975American Airlines

Fri, Oct 9 - Sun, Oct 11

7:15 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

11h 22m2 stops Phoenix Sky Harbor Intl Charlotte Douglas

4:57 pm - 9:55 pmMYR Myrtle Beach Intl-SAF Santa Fe

6h 58m1 stop Dallas/Fort Worth

$981American Airlines

Fri, Oct 9 - Sun, Oct 11

7:15 pm - 8:37 amSAF Santa Fe-MYR Myrtle Beach Intl

11h 22m2 stops Phoenix Sky Harbor Intl Charlotte Douglas

9:22 am - 7:26 pmMYR Myrtle Beach Intl-SAF Santa Fe

12h 04m2 stops Charlotte Douglas Dallas/Fort Worth

$986American Airlines

Fri, Oct 9 - Sun, Oct 11

1:17 pm - 9:46 pmSAF Santa Fe-CHS Charleston

6h 29m1 stop Denver Intl

8:26 am - 2:46 pmCHS Charleston-SAF Santa Fe

8h 20m1 stop Denver Intl

$1,115United Airlines

Fri, Oct 9 - Mon, Oct 12

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United Airlines flights from Santa Fe to South Carolina

Our best United Airlines deals on Santa Fe to South Carolina flight tickets

United Airlines

Jan 6

SAF7:00 amSanta Fe

5h 57m

1 stop

CHS2:57 pmCharleston

Jan 9

CHS4:00 pmCharleston

6h 51m

1 stop

SAF8:51 pmSanta Fe

$467

United Airlines

Jan 6

SAF7:00 amSanta Fe

6h 00m

1 stop

CHS3:00 pmCharleston

Jan 9

CHS6:00 amCharleston

13h 11m

2 stops

SAF5:11 pmSanta Fe

$473

United Airlines

Jan 6

SAF7:00 amSanta Fe

14h 19m

2 stops

CHS11:19 pmCharleston

Jan 9

CHS4:00 pmCharleston

6h 51m

1 stop

SAF8:51 pmSanta Fe

$563

American Airlines flights from Santa Fe to South Carolina

Our best American Airlines deals on Santa Fe to South Carolina flight tickets

American Airlines

Oct 21

SAF3:11 pmSanta Fe

5h 41m

1 stop

MYR10:52 pmMyrtle Beach Intl

Oct 29

MYR4:57 pmMyrtle Beach Intl

6h 58m

1 stop

SAF9:55 pmSanta Fe

$588

American Airlines

Oct 21

SAF3:11 pmSanta Fe

5h 41m

1 stop

MYR10:52 pmMyrtle Beach Intl

Oct 29

MYR5:00 amMyrtle Beach Intl

11h 41m

2 stops

SAF2:41 pmSanta Fe

$594

American Airlines

Oct 21

SAF7:15 pmSanta Fe

11h 22m

2 stops

MYR8:37 amMyrtle Beach Intl

Oct 29

MYR2:11 pmMyrtle Beach Intl

9h 44m

2 stops

SAF9:55 pmSanta Fe

$599

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa FeCharleston

SAF Santa Fe - CHS Charleston

SAFCHS

Santa Fe

Wed 1/6

7:00 am-2:57 pm

1 stop5h 57m

Charleston

Sat 1/9

4:00 pm-8:51 pm

1 stop6h 51m

$467

Quickest round-trip

Santa FeCharleston

SAF Santa Fe - CHS Charleston

SAFCHS

Santa Fe

Wed 1/6

7:00 am-3:00 pm

1 stop6h 00m

Charleston

Sat 1/9

4:02 pm-8:33 pm

1 stop6h 31m

$467

Santa FeCharleston

SAF Santa Fe - CHS Charleston

SAFCHS

Santa Fe

Wed 1/6

7:00 am-3:00 pm

1 stop6h 00m

Charleston

Sat 1/9

6:00 am-5:11 pm

2 stops13h 11m

$473

Santa FeCharleston

SAF Santa Fe - CHS Charleston

SAFCHS

Santa Fe

Wed 1/6

7:00 am-3:00 pm

1 stop6h 00m

Charleston

Sat 1/9

6:00 am-5:11 pm

2 stops13h 11m

$473

Santa FeCharleston

SAF Santa Fe - CHS Charleston

SAFCHS

Santa Fe

Wed 1/6

7:00 am-11:19 pm

2 stops14h 19m

Charleston

Sat 1/9

4:00 pm-8:51 pm

1 stop6h 51m

$563

Santa FeMyrtle Beach

SAF Santa Fe - MYR Myrtle Beach Intl

SAFMYR

Santa Fe

Wed 10/21

3:11 pm-10:52 pm

1 stop5h 41m

Myrtle Beach Intl

Thu 10/29

4:57 pm-9:55 pm

1 stop6h 58m

$588

Santa FeMyrtle Beach

SAF Santa Fe - MYR Myrtle Beach Intl

SAFMYR

Santa Fe

Wed 10/21

3:11 pm-10:52 pm

1 stop5h 41m

Myrtle Beach Intl

Thu 10/29

5:00 am-2:41 pm

2 stops11h 41m

$594

Santa FeMyrtle Beach

SAF Santa Fe - MYR Myrtle Beach Intl

SAFMYR

Santa Fe

Wed 10/21

7:15 pm-8:37 am

2 stops11h 22m

Myrtle Beach Intl

Thu 10/29

2:11 pm-9:55 pm

2 stops9h 44m

$599

Santa FeCharleston

SAF Santa Fe - CHS Charleston

SAFCHS

Santa Fe

Wed 1/6

10:45 am-3:13 pm

2 stops26h 28m

Charleston

Sat 1/9

4:02 pm-8:33 pm

1 stop6h 31m

$616

Santa FeGreenville

SAF Santa Fe - GSP Greenville

SAFGSP

Santa Fe

Sat 10/31

7:00 am-3:03 pm

1 stop6h 03m

Greenville

Wed 11/4

6:20 am-5:10 pm

2 stops12h 50m

$618

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Santa Fe to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Santa Fe to South Carolina flights?

You could potentially save up to 47% on your flight if you consider stops on a Santa Fe to South Carolina flight.

Cheap Santa Fe to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to South Carolina

Best Price Found	$483
Fastest flight time	6h 00m
Direct flights	None

The best one-way flight to South Carolina from Santa Fe in the past 72 hours is $483. The best round-trip flight deal from Santa Fe to South Carolina found on momondo in the last 72 hours is $467.

The fastest flight from Santa Fe to South Carolina takes 6h 00m

There are no direct flights from Santa Fe to South Carolina. There are no popular flight routes from Santa Fe to South Carolina.

Search flight deals

Frequently asked questions about flying from Santa Fe to South Carolina

When did momondo last update prices for flights from Santa Fe Airport to South Carolina?
Prices for flights from Santa Fe Airport to South Carolina are refreshed on a daily basis.
How many operators does momondo search for flights from Santa Fe Airport to South Carolina?
There is 1 operator available for flights from Santa Fe Airport to South Carolina as of October 2026.
How old do you have to be to fly from Santa Fe Airport to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The necessary travel and health documents for your South Carolina trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Santa Fe to South Carolina

Compare and see reviews for airlines that fly from Santa Fe to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $438	Free Cancellation	Rating 7.0 12,132 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Fe to South Carolina for you.

Can I find flights from Santa Fe to South Carolina with flexible booking policies on momondo?

All flight searches from Santa Fe to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Fe to South Carolina?

Once all potential Santa Fe to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to South Carolina right now. Can momondo alert me if prices change?

Price alerts on flights to South Carolina from Santa Fe are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.