Cheap flights from Santa Fe to South America from $543

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Fe to South America departing on 10/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

American Airlines Logo
6:15 am - 4:10 amSAF-LIM
20h 55m2 stops
American Airlines Logo
6:30 am - 10:10 pmLIM-SAF
16h 40m2 stops
$724American Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
United Airlines Logo
1:20 pm - 8:50 amSAF-SCL
15h 30m2 stops
United Airlines Logo
10:45 pm - 2:39 pmSCL-SAF
19h 54m2 stops
$828United Airlines
Find Deal
Sat, Dec 6 - Wed, Dec 10
American Airlines Logo
8:11 am - 4:40 amSAF-LIM
18h 29m2 stops
American Airlines Logo
12:45 am - 8:00 pmLIM-SAF
21h 15m2 stops
$829American Airlines
Find Deal
Fri, Jan 30 - Sat, Feb 14
United Airlines Logo
5:59 pm - 11:00 pmSAF-LIM
28h 01m2 stops
United Airlines Logo
12:40 am - 10:03 pmLIM-SAF
46h 23m2 stops
$834United Airlines
Find Deal
Tue, Sep 30 - Mon, Oct 6
United Airlines Logo
5:59 pm - 11:00 pmSAF-LIM
28h 01m2 stops
United Airlines Logo
12:40 am - 10:03 pmLIM-SAF
22h 23m2 stops
$860United Airlines
Find Deal
Sat, Oct 4 - Mon, Oct 6
American Airlines Logo
12:46 pm - 7:50 amSAF-SCL
15h 04m1 stop
American Airlines Logo
11:15 pm - 9:26 amSCL-SAF
14h 11m1 stop
$879American Airlines
Find Deal
Sat, Jan 31 - Sat, Feb 14
United Airlines Logo
6:05 pm - 8:50 amSAF-SCL
58h 45m2 stops
United Airlines Logo
10:45 pm - 9:32 amSCL-SAF
38h 47m2 stops
$880United Airlines
Find Deal
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
10:43 am - 9:05 amSAF-SCL
18h 22m2 stops
American Airlines Logo
11:15 pm - 9:26 amSCL-SAF
14h 11m1 stop
$884American Airlines
Find Deal
Sat, Jan 31 - Sat, Feb 14
American Airlines Logo
12:46 pm - 4:40 amSAF-LIM
13h 54m2 stops
American Airlines Logo
10:55 pm - 3:47 pmLIM-SAF
18h 52m2 stops
$902American Airlines
Find Deal
Fri, Jan 30 - Sun, Feb 15
American Airlines Logo
12:36 pm - 7:50 amSAF-SCL
15h 14m1 stop
American Airlines Logo
11:15 pm - 4:21 pmSCL-SAF
21h 06m1 stop
$979American Airlines
Find Deal
Sat, Dec 6 - Wed, Dec 10

American Airlines flights from Santa Fe to South America

Our best American Airlines deals on Santa Fe to South America flight tickets
American Airlines
Sep 30
SAF6:15 amSanta Fe
20h 55m
2 stops
LIM4:10 amLima J Chavez Intl
Oct 7
LIM6:30 amLima J Chavez Intl
16h 40m
2 stops
SAF10:10 pmSanta Fe
American Airlines
Jan 30
SAF8:11 amSanta Fe
18h 29m
2 stops
LIM4:40 amLima J Chavez Intl
Feb 14
LIM12:45 amLima J Chavez Intl
21h 15m
2 stops
SAF8:00 pmSanta Fe
American Airlines
Jan 31
SAF12:46 pmSanta Fe
15h 04m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Feb 14
SCL11:15 pmSantiago Arturo Merino Benitez
14h 11m
1 stop
SAF9:26 amSanta Fe

United Airlines flights from Santa Fe to South America

Our best United Airlines deals on Santa Fe to South America flight tickets
United Airlines
Dec 6
SAF1:20 pmSanta Fe
15h 30m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Dec 10
SCL10:45 pmSantiago Arturo Merino Benitez
19h 54m
2 stops
SAF2:39 pmSanta Fe
United Airlines
Sep 30
SAF5:59 pmSanta Fe
28h 01m
2 stops
LIM11:00 pmLima J Chavez Intl
Oct 6
LIM12:40 amLima J Chavez Intl
46h 23m
2 stops
SAF10:03 pmSanta Fe
United Airlines
Oct 4
SAF5:59 pmSanta Fe
28h 01m
2 stops
LIM11:00 pmLima J Chavez Intl
Oct 6
LIM12:40 amLima J Chavez Intl
22h 23m
2 stops
SAF10:03 pmSanta Fe

momondo Fare Finder

 
Customize your flight search to find flights from Santa Fe to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Santa Fe to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Tue 9/30

6:15 am-4:10 am

2 stops20h 55m

Lima J Chavez Intl

Tue 10/7

6:30 am-10:10 pm

2 stops16h 40m

$724

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 12/6

1:20 pm-8:50 am

2 stops15h 30m

Santiago Arturo Merino Benitez

Wed 12/10

10:45 pm-2:39 pm

2 stops19h 54m

$828

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Fri 1/30

8:11 am-4:40 am

2 stops18h 29m

Lima J Chavez Intl

Sat 2/14

12:45 am-8:00 pm

2 stops21h 15m

$829

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Tue 9/30

5:59 pm-11:00 pm

2 stops28h 01m

Lima J Chavez Intl

Mon 10/6

12:40 am-10:03 pm

2 stops46h 23m

$834

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Sat 10/4

5:59 pm-11:00 pm

2 stops28h 01m

Lima J Chavez Intl

Mon 10/6

12:40 am-10:03 pm

2 stops22h 23m

$860

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 1/31

12:46 pm-7:50 am

1 stop15h 04m

Santiago Arturo Merino Benitez

Sat 2/14

11:15 pm-9:26 am

1 stop14h 11m

$879

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 1/31

6:05 pm-8:50 am

2 stops58h 45m

Santiago Arturo Merino Benitez

Sat 2/14

10:45 pm-9:32 am

2 stops38h 47m

$880

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 1/31

10:43 am-9:05 am

2 stops18h 22m

Santiago Arturo Merino Benitez

Sat 2/14

11:15 pm-9:26 am

1 stop14h 11m

$884

Santa FeLima

SAF - LIM

SAFLIM

Santa Fe

Fri 1/30

12:46 pm-4:40 am

2 stops13h 54m

Lima J Chavez Intl

Sun 2/15

10:55 pm-3:47 pm

2 stops18h 52m

$902

Santa FeSantiago

SAF - SCL

SAFSCL

Santa Fe

Sat 12/6

12:36 pm-7:50 am

1 stop15h 14m

Santiago Arturo Merino Benitez

Wed 12/10

11:15 pm-4:21 pm

1 stop21h 06m

$979

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santa Fe to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Santa Fe to South America is on a Monday when prices can be found for as low as $967. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Santa Fe to South America for around $1,499.

Cheap Santa Fe to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Fe to South America

Direct flights

None
There are no direct flights from Santa Fe to South America. There are no popular flight routes from Santa Fe to South America.
  • When did momondo last update prices for flights from Santa Fe Airport to South America?

    Prices for flights from Santa Fe Airport to South America were last updated today.

  • How many operators does momondo search for flights from Santa Fe Airport to South America?

  • How old do you have to be to fly from Santa Fe Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Fe Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Santa Fe to South America

Compare and see reviews for airlines that fly from Santa Fe to South America with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $647Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santa Fe to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Fe to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Fe to South America with flexible booking policies on momondo?

All flight searches from Santa Fe to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Fe to South America?

Once all potential Santa Fe to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Santa Fe to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Santa Fe and alert you when they change.

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1 adult
Tue 9/9
Tue 9/16

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Popular flights according to clicks in the last 7 days on momondo