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Cheap flights from San Luis Obispo to Knoxville from $329

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from San Luis Obispo to Knoxville departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Luis Obispo to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:00 am - 3:14 pm
SBP
-
TYS
7h 14m1 stop
United Airlines Logo
4:25 pm - 9:15 pm
TYS
-
SBP
7h 50m1 stop
$329United Airlines
mié., ene. 7 - mié., ene. 14
United Airlines Logo
5:00 am - 3:14 pm
SBP
-
TYS
7h 14m1 stop
United Airlines Logo
1:59 pm - 11:44 pm
TYS
-
SBP
12h 45m2 stops
$334United Airlines
mié., ene. 7 - mié., ene. 14
United Airlines Logo
5:00 am - 6:05 pm
SBP
-
TYS
10h 05m2 stops
United Airlines Logo
4:25 pm - 11:57 pm
TYS
-
SBP
10h 32m2 stops
$339United Airlines
mié., ene. 7 - mié., ene. 14
United Airlines Logo
5:00 am - 3:02 pm
SBP
-
TYS
7h 02m1 stop
United Airlines Logo
4:25 pm - 9:14 pm
TYS
-
SBP
7h 49m1 stop
$373United Airlines
mié., abr. 29 - jue., may. 7
United Airlines Logo
5:00 am - 3:02 pm
SBP
-
TYS
7h 02m1 stop
United Airlines Logo
7:00 am - 5:11 pm
TYS
-
SBP
13h 11m2 stops
$378United Airlines
mié., abr. 29 - jue., may. 7
United Airlines Logo
6:05 am - 8:46 pm
SBP
-
TYS
11h 41m2 stops
United Airlines Logo
4:25 pm - 11:44 pm
TYS
-
SBP
10h 19m2 stops
$414United Airlines
mié., abr. 29 - jue., may. 7
United Airlines Logo
5:00 am - 8:52 pm
SBP
-
TYS
12h 52m2 stops
United Airlines Logo
2:25 pm - 11:57 pm
TYS
-
SBP
12h 32m2 stops
$419United Airlines
sáb., ene. 31 - mar., feb. 3
United Airlines Logo
5:58 pm - 10:57 am
SBP
-
TYS
13h 59m2 stops
United Airlines Logo
9:30 am - 9:15 pm
TYS
-
SBP
14h 45m2 stops
$439United Airlines
sáb., ene. 31 - mar., feb. 3
United Airlines Logo
5:00 am - 8:52 pm
SBP
-
TYS
12h 52m2 stops
United Airlines Logo
4:25 pm - 9:15 pm
TYS
-
SBP
7h 50m1 stop
$444United Airlines
sáb., ene. 31 - mar., feb. 3
United Airlines Logo
6:06 am - 8:52 pm
SBP
-
TYS
11h 46m2 stops
United Airlines Logo
4:25 pm - 9:15 pm
TYS
-
SBP
7h 50m1 stop
$487United Airlines
sáb., ene. 31 - mar., feb. 3

United Airlines flights from San Luis Obispo to Knoxville

Our best United Airlines deals on San Luis Obispo to Knoxville flight tickets
United Airlines
Jan 7
SBP5:00 amSan Luis Obispo County
7h 14m
1 stop
TYS3:14 pmKnoxville McGhee Tyson
Jan 14
TYS4:25 pmKnoxville McGhee Tyson
7h 50m
1 stop
SBP9:15 pmSan Luis Obispo County
$329
Find similar
United Airlines
Jan 7
SBP5:00 amSan Luis Obispo County
7h 14m
1 stop
TYS3:14 pmKnoxville McGhee Tyson
Jan 14
TYS1:59 pmKnoxville McGhee Tyson
12h 45m
2 stops
SBP11:44 pmSan Luis Obispo County
$334
Find similar
United Airlines
Jan 7
SBP5:00 amSan Luis Obispo County
10h 05m
2 stops
TYS6:05 pmKnoxville McGhee Tyson
Jan 14
TYS4:25 pmKnoxville McGhee Tyson
10h 32m
2 stops
SBP11:57 pmSan Luis Obispo County
$339
Find similar

American Airlines flights from San Luis Obispo to Knoxville

Our best American Airlines deals on San Luis Obispo to Knoxville flight tickets
American Airlines
May 21
SBP12:23 pmSan Luis Obispo County
8h 26m
1 stop
TYS11:49 pmKnoxville McGhee Tyson
May 26
TYS6:00 amKnoxville McGhee Tyson
8h 27m
1 stop
SBP11:27 amSan Luis Obispo County
$550
Find similar
American Airlines
May 21
SBP12:23 pmSan Luis Obispo County
8h 26m
1 stop
TYS11:49 pmKnoxville McGhee Tyson
May 26
TYS2:32 pmKnoxville McGhee Tyson
10h 23m
2 stops
SBP9:55 pmSan Luis Obispo County
$555
Find similar
American Airlines
Dec 19
SBP9:57 amSan Luis Obispo County
11h 41m
2 stops
TYS12:38 amKnoxville McGhee Tyson
Dec 22
TYS4:29 pmKnoxville McGhee Tyson
9h 25m
2 stops
SBP10:54 pmSan Luis Obispo County
$607
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Luis Obispo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 11, 2025.
Use the filters below to find and compare flights from San Luis Obispo to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 1/7

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

mié. 1/14

4:25 pm-9:15 pm

1 stop7h 50m

$329

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 1/7

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

mié. 1/14

1:59 pm-11:44 pm

2 stops12h 45m

$334

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 1/7

5:00 am-6:05 pm

2 stops10h 05m

Knoxville McGhee Tyson

mié. 1/14

4:25 pm-11:57 pm

2 stops10h 32m

$339

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 4/29

5:00 am-3:02 pm

1 stop7h 02m

Knoxville McGhee Tyson

jue. 5/7

4:25 pm-9:14 pm

1 stop7h 49m

$373

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 4/29

5:00 am-3:02 pm

1 stop7h 02m

Knoxville McGhee Tyson

jue. 5/7

7:00 am-5:11 pm

2 stops13h 11m

$378

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 4/29

6:05 am-8:46 pm

2 stops11h 41m

Knoxville McGhee Tyson

jue. 5/7

4:25 pm-11:44 pm

2 stops10h 19m

$414

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 1/31

5:00 am-8:52 pm

2 stops12h 52m

Knoxville McGhee Tyson

mar. 2/3

2:25 pm-11:57 pm

2 stops12h 32m

$419

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 1/31

5:58 pm-10:57 am

2 stops13h 59m

Knoxville McGhee Tyson

mar. 2/3

9:30 am-9:15 pm

2 stops14h 45m

$439

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 1/31

5:00 am-8:52 pm

2 stops12h 52m

Knoxville McGhee Tyson

mar. 2/3

4:25 pm-9:15 pm

1 stop7h 50m

$444

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 1/31

6:06 am-8:52 pm

2 stops11h 46m

Knoxville McGhee Tyson

mar. 2/3

4:25 pm-9:15 pm

1 stop7h 50m

$487

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Knoxville from

How to get the cheapest flight ticket from San Luis Obispo to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of October is, on average, the cheapest month to fly to Knoxville from San Luis Obispo, with most prices found around $308. If you aren’t able to travel during the month of October, then book flights to Knoxville from San Luis Obispo during August instead. Flights to Knoxville in August, while not as cheap as those in October, still average around $311.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from San Luis Obispo to Knoxville is on a Monday. Travelers who choose to depart for Knoxville on a Monday will often find tickets for as low as $398. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from San Luis Obispo to Knoxville for around $552.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from San Luis Obispo to Knoxville when you can find flight prices for as low as $453. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $485.

When to book flights from San Luis Obispo to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from San Luis Obispo to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Luis Obispo to Knoxville (SBP to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Luis Obispo to Knoxville

Fastest flight time

7h 00m

Direct flights

None
The fastest flight from San Luis Obispo to Knoxville takes 7h 00m
There are no direct flights from San Luis Obispo to Knoxville. There are no popular flight routes from San Luis Obispo to Knoxville.
Search flight deals

  • How far is San Luis Obispo County to Knoxville McGhee Tyson by plane?

    The distance between San Luis Obispo County and Knoxville McGhee Tyson is about 2050.2 mi. In terms of flight time, this usually takes a little over 7h 00m.

  • When did momondo last update prices for flights from San Luis Obispo County Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from San Luis Obispo County Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from San Luis Obispo County Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from San Luis Obispo County Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Luis Obispo County Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from San Luis Obispo to Knoxville?

Best airlines flying from San Luis Obispo to Knoxville

Compare and see reviews for airlines that fly from San Luis Obispo to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
United AirlinesPriceFrom $278Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Maryville
Crossville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from San Luis Obispo to Knoxville?

It is quick and easy to find San Luis Obispo to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from San Luis Obispo to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from San Luis Obispo with this policy.

How can momondo help me find flights from San Luis Obispo to Knoxville?

momondo helps you find the best flight between San Luis Obispo and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from San Luis Obispo to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from San Luis Obispo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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