What day of the week experiences the fewest flight delays on this route?

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

What is the cheapest airline that flies from San Francisco to Panama?

Avianca and United Airlines are the most popular carriers operating from San Francisco to Panama

How many flights depart from San Francisco to Panama on average per week?

31 flights are operational weekly from San Francisco to Panama as of December 2025. The most popular departure day for this route is Mon, with 16% of flights per week taking off on this day.

What airlines fly to Panama?

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama from San Francisco according to our data. Copa Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

How often are flights from San Francisco to Panama delayed?

Historically, on average around 8% of flights between San Francisco and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 142 minutes.

How many flights depart from San Francisco to Panama on average per day?

The number of flights available between San Francisco and Panama is 4 per day as of December 2025. The most frequent departure time is 12:00AM, with 58% of daily flights leaving in the morning.

Which airline has the best punctuality record on San Francisco to Panama flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 6% of their flights experiencing any sort of delay.

What is the most punctual flight time for San Francisco to Panama flights?

Generally, flights departing at night tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

When did momondo last update prices for flights from San Francisco Airport to Panama?

Prices for flights from San Francisco Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from San Francisco Airport to Panama?

As of December 2025, there are 5 operators available to choose from for flights from San Francisco Airport to Panama.

How old do you have to be to fly from San Francisco Airport to Panama?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$200 Cheap Flights from San Francisco to Panama in 2025/26

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Enter your travel dates to find the best prices.

12:42 am - 10:46 am

SFO

PTY

7h 04mnonstop

6:27 pm - 11:20 pm

PTY

SFO

7h 53mnonstop

$637Copa Airlines

dom., feb. 8 - mié., feb. 18

12:05 am - 10:25 am

SFO

PTY

8h 20m1 stop

10:05 pm - 12:35 pm

PTY

SFO

16h 30m2 stops

$640Avianca

vie., abr. 3 - lun., abr. 13

12:05 am - 10:25 am

SFO

PTY

8h 20m1 stop

3:40 pm - 10:45 pm

PTY

SFO

9h 05m1 stop

$641Avianca

vie., abr. 3 - mié., abr. 15

1:35 am - 6:55 pm

SFO

PTY

14h 20m1 stop

7:50 pm - 9:39 pm

PTY

SFO

52h 49m2 stops

$643Multiple Airlines

sáb., feb. 14 - sáb., feb. 21

11:10 pm - 4:55 pm

SFO

PTY

14h 45m2 stops

3:50 pm - 11:20 pm

PTY

SFO

10h 30m1 stop

$644Avianca

sáb., feb. 14 - jue., feb. 19

1:35 am - 6:55 pm

SFO

PTY

14h 20m1 stop

10:26 am - 9:39 pm

PTY

SFO

14h 13m1 stop

$646Multiple Airlines

mar., feb. 3 - jue., feb. 19

1:20 pm - 10:30 am

SFO

PTY

18h 10m1 stop

7:50 pm - 12:00 pm

PTY

SFO

19h 10m1 stop

$647Avianca

lun., ene. 12 - sáb., ene. 17

12:54 am - 10:46 am

SFO

PTY

6h 52mnonstop

5:51 pm - 11:40 pm

PTY

SFO

7h 49mnonstop

$652Copa Airlines

jue., mar. 5 - mié., mar. 11

7:10 pm - 5:31 pm

SFO

DAV

19h 21m2 stops

9:48 am - 9:53 am

DAV

SFO

27h 05m2 stops

$1,119United Airlines

mar., feb. 3 - mar., feb. 17

11:59 pm - 9:04 am

SFO

DAV

30h 05m2 stops

9:48 am - 7:31 am

DAV

SFO

24h 43m2 stops

$1,134United Airlines

dom., feb. 1 - dom., mar. 1

Copa Airlines flights from San Francisco to Panama

Our best Copa Airlines deals on San Francisco to Panama flight tickets

Copa Airlines

Feb 8

SFO12:42 amSan Francisco

7h 04m

PTY10:46 amPanama City Tocumen Intl

Feb 18

PTY6:27 pmPanama City Tocumen Intl

7h 53m

SFO11:20 pmSan Francisco

$637

Find similar

Copa Airlines

Mar 5

SFO12:54 amSan Francisco

6h 52m

PTY10:46 amPanama City Tocumen Intl

Mar 11

PTY5:51 pmPanama City Tocumen Intl

7h 49m

SFO11:40 pmSan Francisco

$652

Find similar

Copa Airlines

Mar 13

SFO1:54 amSan Francisco

6h 52m

PTY10:46 amPanama City Tocumen Intl

Mar 21

PTY5:51 pmPanama City Tocumen Intl

7h 49m

SFO11:40 pmSan Francisco

$667

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Avianca flights from San Francisco to Panama

Our best Avianca deals on San Francisco to Panama flight tickets

Avianca

Apr 3

SFO12:05 amSan Francisco

8h 20m

1 stop

PTY10:25 amPanama City Tocumen Intl

Apr 13

PTY10:05 pmPanama City Tocumen Intl

16h 30m

2 stops

SFO12:35 pmSan Francisco

$640

Find similar

Avianca

Apr 3

SFO12:05 amSan Francisco

8h 20m

1 stop

PTY10:25 amPanama City Tocumen Intl

Apr 15

PTY3:40 pmPanama City Tocumen Intl

9h 05m

1 stop

SFO10:45 pmSan Francisco

$641

Find similar

Avianca

Feb 14

SFO11:10 pmSan Francisco

8h 20m

1 stop

PTY10:30 amPanama City Tocumen Intl

Feb 19

PTY3:50 pmPanama City Tocumen Intl

10h 30m

1 stop

SFO11:20 pmSan Francisco

$644

Find similar

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

dom. 2/8

12:42 am-10:46 am

Nonstop7h 04m

Panama City Tocumen Intl

mié. 2/18

6:27 pm-11:20 pm

Nonstop7h 53m

$637

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

vie. 4/3

12:05 am-10:25 am

1 stop8h 20m

Panama City Tocumen Intl

lun. 4/13

10:05 pm-12:35 pm

2 stops16h 30m

$640

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

vie. 4/3

12:05 am-10:25 am

1 stop8h 20m

Panama City Tocumen Intl

mié. 4/15

3:40 pm-10:45 pm

1 stop9h 05m

$641

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

sáb. 2/14

1:35 am-6:55 pm

1 stop14h 20m

Panama City Tocumen Intl

sáb. 2/21

7:50 pm-9:39 pm

2 stops52h 49m

$643

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

sáb. 2/14

11:10 pm-4:55 pm

2 stops14h 45m

Panama City Tocumen Intl

jue. 2/19

3:50 pm-11:20 pm

1 stop10h 30m

$644

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 2/3

1:35 am-6:55 pm

1 stop14h 20m

Panama City Tocumen Intl

jue. 2/19

10:26 am-9:39 pm

1 stop14h 13m

$646

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

lun. 1/12

1:20 pm-10:30 am

1 stop18h 10m

Panama City Tocumen Intl

sáb. 1/17

7:50 pm-12:00 pm

1 stop19h 10m

$647

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

jue. 3/5

12:54 am-10:46 am

Nonstop6h 52m

Panama City Tocumen Intl

mié. 3/11

5:51 pm-11:40 pm

Nonstop7h 49m

$652

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

mar. 2/3

7:10 pm-5:31 pm

2 stops19h 21m

David Enrique Malek

mar. 2/17

9:48 am-9:53 am

2 stops27h 05m

$1,119

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

dom. 2/1

11:59 pm-9:04 am

2 stops30h 05m

David Enrique Malek

dom. 3/1

9:48 am-7:31 am

2 stops24h 43m

$1,134

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Other information

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from San Francisco, with most prices found around $533. If you don’t want to visit Panama in October, then you should wait until August to fly from San Francisco, when ticket prices are also cheap, with an average price of $584.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from San Francisco. The lowest ticket price found for a Tuesday departure recently was $644. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to Panama for around $764.

What is the cheapest time of day to depart on your flight to Panama?

At noon is the cheapest time of day to fly from San Francisco to Panama when you can find flight prices for as low as $498. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $1,556 per ticket.

What is the cheapest San Francisco to Panama flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $648 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Francisco for as low as $602 on momondo.

What cabin class options are available on San Francisco to Panama flights?

There are 3 cabin classes available to choose from on San Francisco to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Francisco to Panama flights?

You could potentially save up to 43% on your flight if you consider stops on a San Francisco to Panama flight.

Cheap San Francisco to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama

Best Price Found	$309
Fastest flight time	6h 53m
Direct flights	Every day
Airports in Panama	21 airports

The best one-way flight to Panama from San Francisco in the past 72 hours is $309. The best round-trip flight deal from San Francisco to Panama found on momondo in the last 72 hours is $651.

The fastest flight from San Francisco to Panama takes 6h 53m

Direct flights go from San Francisco to Panama every day.

There are 21 airports in Panama. From San Francisco there are direct flights to Panama City Tocumen Intl (PTY).

Search flight deals

When did momondo last update prices for flights from San Francisco Airport to Panama?
Prices for flights from San Francisco Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from San Francisco Airport to Panama?
As of December 2025, there are 5 operators available to choose from for flights from San Francisco Airport to Panama.
How old do you have to be to fly from San Francisco Airport to Panama?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from San Francisco to Panama?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from San Francisco to Panama is Boeing 737 MAX 9 (46.32% of total bookings). The next most popular plane models are Boeing 737 MAX 8 (31.76%), Boeing 737-900 (12.50%), and Airbus A320neo (7.94%).

Best airlines flying from San Francisco to Panama

Compare and see reviews for airlines that fly from San Francisco to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $387	Free Cancellation	Rating 7.9 8,015 reviews	Search Delta flights
Avianca	PriceFrom $424	Free Cancellation	Rating 6.6 2,491 reviews	Search Avianca flights
Copa Airlines	PriceFrom $503	Free Cancellation	Rating 7.6 1,557 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $533	Free Cancellation	Rating 7.4 9,106 reviews	Search United Airlines flights
American Airlines	PriceFrom $588	Free Cancellation	Rating 7.2 11,051 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Francisco to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Francisco to Panama with flexible booking policies on momondo?

Flights from San Francisco to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Panama?

momondo provides multiple filters to help you find the best flight to Panama from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama trip

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Popular cities in Panama

Flights to Panama Cityfrom $325

Flights to Bocas del Torofrom $663

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Cheap flights from San Francisco to Panama from $200

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Panama departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Copa Airlines flights from San Francisco to Panama

Our best Copa Airlines deals on San Francisco to Panama flight tickets

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Our best Avianca deals on San Francisco to Panama flight tickets

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See travel insights to Panama from

How to get the cheapest flight ticket from San Francisco to Panama

What is the cheapest month to fly to Panama?

What is the cheapest day to depart on your flight to Panama?

What is the cheapest time of day to depart on your flight to Panama?

What is the cheapest San Francisco to Panama flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama flight prices

How far in advance should I book a flight to Panama?

What cabin class options are available on San Francisco to Panama flights?

There are 3 cabin classes available to choose from on San Francisco to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Francisco to Panama flights?

You could potentially save up to 43% on your flight if you consider stops on a San Francisco to Panama flight.

What is the cheapest airline that flies from San Francisco to Panama?

Avianca and United Airlines are the most popular carriers operating from San Francisco to Panama

What airlines fly to Panama?

How often are flights from San Francisco to Panama delayed?

Historically, on average around 8% of flights between San Francisco and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 142 minutes.

What is the most punctual flight time for San Francisco to Panama flights?

Generally, flights departing at night tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

Which airline has the best punctuality record on San Francisco to Panama flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 6% of their flights experiencing any sort of delay.

How many flights depart from San Francisco to Panama on average per day?

The number of flights available between San Francisco and Panama is 4 per day as of December 2025. The most frequent departure time is 12:00AM, with 58% of daily flights leaving in the morning.

How many flights depart from San Francisco to Panama on average per week?

31 flights are operational weekly from San Francisco to Panama as of December 2025. The most popular departure day for this route is Mon, with 16% of flights per week taking off on this day.

Cheap San Francisco to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama

Best Price Found

Fastest flight time

Direct flights

Airports in Panama

When did momondo last update prices for flights from San Francisco Airport to Panama?

How many operators does momondo search for flights from San Francisco Airport to Panama?

How old do you have to be to fly from San Francisco Airport to Panama?

What documentation or ID do you need to fly to Panama?

What is the most popular plane model from San Francisco to Panama?

Best airlines flying from San Francisco to Panama

Compare and see reviews for airlines that fly from San Francisco to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama?

Can I find flights from San Francisco to Panama with flexible booking policies on momondo?

How can momondo help me find flights from San Francisco to Panama?

I’m not ready to book a flight from San Francisco to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo