What is the cheapest airline that flies from San Francisco to Panama?

Avianca is the most popular carrier operating from San Francisco to Panama

How many flights depart from San Francisco to Panama on average per day?

The number of flights available between San Francisco and Panama is 4 per day as of September 2025. The most frequent departure time is 1:00AM, with 58% of daily flights leaving in the morning.

What airlines fly to Panama?

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama from San Francisco according to our data. Copa Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

How many flights depart from San Francisco to Panama on average per week?

33 flights are operational weekly from San Francisco to Panama as of September 2025. The most popular departure day for this route is Mon, with 15% of flights per week taking off on this day.

When did momondo last update prices for flights from San Francisco Airport to Panama?

Prices for flights from San Francisco Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from San Francisco Airport to Panama?

As of September 2025, there are 5 operators available to choose from for flights from San Francisco Airport to Panama.

How old do you have to be to fly from San Francisco Airport to Panama?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$207 Cheap Flights from San Francisco to Panama in 2025/26

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Find the cheapest flights from San Francisco to Panama

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

11:10 pm - 10:20 amSFO-PTY

8h 10m1 stop

5:55 pm - 12:00 pmPTY-SFO

21h 05m2 stops

$484Avianca

Find Deal

Wed, Feb 18 - Mon, Mar 2

2:30 am - 4:15 pmSFO-PTY

11h 45m1 stop

3:20 am - 10:45 pmPTY-SFO

21h 25m2 stops

$485Avianca

Find Deal

Thu, Oct 16 - Tue, May 19

2:20 pm - 10:25 amSFO-PTY

18h 05m1 stop

2:55 am - 10:50 pmPTY-SFO

21h 55m2 stops

$489Avianca

Find Deal

Wed, Oct 22 - Sat, Oct 25

12:36 am - 10:46 amSFO-PTY

7h 10mnonstop

6:27 pm - 11:17 pmPTY-SFO

7h 50mnonstop

$549Copa Airlines

Find Deal

Fri, Nov 28 - Tue, Dec 9

12:42 am - 10:46 amSFO-PTY

7h 04mnonstop

6:27 pm - 11:20 pmPTY-SFO

7h 53mnonstop

$637Copa Airlines

Find Deal

Tue, Jan 20 - Mon, Jan 26

12:36 am - 10:46 amSFO-PTY

7h 10mnonstop

6:27 pm - 11:17 pmPTY-SFO

7h 50mnonstop

$649Copa Airlines

Find Deal

Sat, Nov 29 - Thu, Dec 11

8:45 am - 6:49 pmSFO-PTY

7h 04mnonstop

3:35 pm - 8:29 pmPTY-SFO

7h 54mnonstop

$659United Airlines

Find Deal

Mon, Dec 15 - Wed, Dec 24

5:00 am - 5:07 pmSFO-PTY

9h 07m1 stop

3:35 pm - 8:29 pmPTY-SFO

7h 54mnonstop

$663United Airlines

Find Deal

Mon, Dec 15 - Wed, Dec 24

8:45 am - 5:31 pmSFO-DAV

29h 46m1 stop

9:48 am - 8:29 pmDAV-SFO

13h 41m1 stop

$1,084United Airlines

Find Deal

Tue, Feb 3 - Tue, Feb 17

12:42 am - 5:31 pmSFO-DAV

13h 49m1 stop

6:38 pm - 11:20 pmDAV-SFO

31h 42m1 stop

$1,184Copa Airlines

Find Deal

Sun, Feb 22 - Fri, Feb 27

Avianca flights from San Francisco to Panama

Our best Avianca deals on San Francisco to Panama flight tickets

Avianca

Feb 18

SFO11:10 pmSan Francisco

8h 10m

1 stop

PTY10:20 amPanama City Tocumen Intl

Mar 2

PTY5:55 pmPanama City Tocumen Intl

21h 05m

2 stops

SFO12:00 pmSan Francisco

$484

Find similar

Avianca

Oct 16

SFO2:30 amSan Francisco

11h 45m

1 stop

PTY4:15 pmPanama City Tocumen Intl

May 19

PTY3:20 amPanama City Tocumen Intl

21h 25m

2 stops

SFO10:45 pmSan Francisco

$485

Find similar

Avianca

Oct 22

SFO2:20 pmSan Francisco

18h 05m

1 stop

PTY10:25 amPanama City Tocumen Intl

Oct 25

PTY2:55 amPanama City Tocumen Intl

21h 55m

2 stops

SFO10:50 pmSan Francisco

$489

Find similar

Copa Airlines flights from San Francisco to Panama

Our best Copa Airlines deals on San Francisco to Panama flight tickets

Copa Airlines

Nov 28

SFO12:36 amSan Francisco

7h 10m

PTY10:46 amPanama City Tocumen Intl

Dec 9

PTY6:27 pmPanama City Tocumen Intl

7h 50m

SFO11:17 pmSan Francisco

$549

Find similar

Copa Airlines

Jan 20

SFO12:42 amSan Francisco

7h 04m

PTY10:46 amPanama City Tocumen Intl

Jan 26

PTY6:27 pmPanama City Tocumen Intl

7h 53m

SFO11:20 pmSan Francisco

$637

Find similar

Copa Airlines

Nov 29

SFO12:36 amSan Francisco

7h 10m

PTY10:46 amPanama City Tocumen Intl

Dec 11

PTY6:27 pmPanama City Tocumen Intl

7h 50m

SFO11:17 pmSan Francisco

$649

Find similar

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 2/18

11:10 pm-10:20 am

1 stop8h 10m

Panama City Tocumen Intl

Mon 3/2

5:55 pm-12:00 pm

2 stops21h 05m

$484

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Thu 10/16

2:30 am-4:15 pm

1 stop11h 45m

Panama City Tocumen Intl

Tue 5/19

3:20 am-10:45 pm

2 stops21h 25m

$485

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Wed 10/22

2:20 pm-10:25 am

1 stop18h 05m

Panama City Tocumen Intl

Sat 10/25

2:55 am-10:50 pm

2 stops21h 55m

$489

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Fri 11/28

12:36 am-10:46 am

Nonstop7h 10m

Panama City Tocumen Intl

Tue 12/9

6:27 pm-11:17 pm

Nonstop7h 50m

$549

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Tue 1/20

12:42 am-10:46 am

Nonstop7h 04m

Panama City Tocumen Intl

Mon 1/26

6:27 pm-11:20 pm

Nonstop7h 53m

$637

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Sat 11/29

12:36 am-10:46 am

Nonstop7h 10m

Panama City Tocumen Intl

Thu 12/11

6:27 pm-11:17 pm

Nonstop7h 50m

$649

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 12/15

8:45 am-6:49 pm

Nonstop7h 04m

Panama City Tocumen Intl

Wed 12/24

3:35 pm-8:29 pm

Nonstop7h 54m

$659

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

Mon 12/15

5:00 am-5:07 pm

1 stop9h 07m

Panama City Tocumen Intl

Wed 12/24

3:35 pm-8:29 pm

Nonstop7h 54m

$663

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Tue 2/3

8:45 am-5:31 pm

1 stop29h 46m

David Enrique Malek

Tue 2/17

9:48 am-8:29 pm

1 stop13h 41m

$1,084

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

Sun 2/22

12:42 am-5:31 pm

1 stop13h 49m

David Enrique Malek

Fri 2/27

6:38 pm-11:20 pm

1 stop31h 42m

$1,184

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How to get the cheapest flight ticket from San Francisco to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from San Francisco, with most prices found around $580. If you don’t want to visit Panama in August, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $608.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from San Francisco. The lowest ticket price found for a Tuesday departure recently was $631. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to Panama for around $752.

What is the cheapest time of day to depart on your flight to Panama?

At noon is the cheapest time of day to fly from San Francisco to Panama when you can find flight prices for as low as $498. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $756 per ticket.

What is the cheapest San Francisco to Panama flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $654 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Francisco for as low as $596 on momondo.

What cabin class options are available on San Francisco to Panama flights?

There are 3 cabin classes available to choose from on San Francisco to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Francisco to Panama flights?

You could potentially save up to 4% on your flight if you consider stops on a San Francisco to Panama flight.

Cheap San Francisco to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama

Best Price Found	$347
Fastest flight time	6h 52m
Direct flights	Every day
Airports in Panama	1 airport

The best one-way flight to Panama from San Francisco in the past 72 hours is $347. The best round-trip flight deal from San Francisco to Panama found on momondo in the last 72 hours is $498.

The fastest flight from San Francisco to Panama takes 6h 52m

Direct flights go from San Francisco to Panama every day.

There is 1 airport near Panama: Panama City Tocumen Intl (PTY)

Search flight deals

When did momondo last update prices for flights from San Francisco Airport to Panama?
Prices for flights from San Francisco Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from San Francisco Airport to Panama?
As of September 2025, there are 5 operators available to choose from for flights from San Francisco Airport to Panama.
How old do you have to be to fly from San Francisco Airport to Panama?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from San Francisco to Panama?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from San Francisco to Panama is Boeing 737 MAX 8 (50.11% of total bookings). The next most popular plane models are Boeing 737 MAX 9 (40.26%), Boeing 737-900 (6.42%), and Airbus A320neo (1.28%).

Best airlines flying from San Francisco to Panama

Compare and see reviews for airlines that fly from San Francisco to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $387	Free Cancellation	Rating 7.9 7,961 reviews	Search Delta flights
Avianca	PriceFrom $408	Free Cancellation	Rating 6.7 2,436 reviews	Search Avianca flights
Copa Airlines	PriceFrom $503	Free Cancellation	Rating 7.6 1,533 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $533	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights
American Airlines	PriceFrom $544	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Francisco to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Francisco to Panama with flexible booking policies on momondo?

Flights from San Francisco to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Panama?

momondo provides multiple filters to help you find the best flight to Panama from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Popular cities in Panama

Flights to Panama Cityfrom $248

Flights to Bocas del Torofrom $516

Flights to Davidfrom $296

Flights to Changuinola

Cheap flights from San Francisco to Panama from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Panama departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

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Find the cheapest flights from San Francisco to Panama

Cheap round-trip flights

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Cheap last minute flights

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Avianca flights from San Francisco to Panama

Our best Avianca deals on San Francisco to Panama flight tickets

Copa Airlines flights from San Francisco to Panama

Our best Copa Airlines deals on San Francisco to Panama flight tickets

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How to get the cheapest flight ticket from San Francisco to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from San Francisco, with most prices found around $580. If you don’t want to visit Panama in August, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $608.

What is the cheapest day to depart on your flight to Panama?

What is the cheapest time of day to depart on your flight to Panama?

What is the cheapest San Francisco to Panama flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama flight prices

How far in advance should I book a flight to Panama?

What cabin class options are available on San Francisco to Panama flights?

There are 3 cabin classes available to choose from on San Francisco to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Francisco to Panama flights?

You could potentially save up to 4% on your flight if you consider stops on a San Francisco to Panama flight.

What is the cheapest airline that flies from San Francisco to Panama?

Avianca is the most popular carrier operating from San Francisco to Panama

What airlines fly to Panama?

How many flights depart from San Francisco to Panama on average per day?

The number of flights available between San Francisco and Panama is 4 per day as of September 2025. The most frequent departure time is 1:00AM, with 58% of daily flights leaving in the morning.

How many flights depart from San Francisco to Panama on average per week?

33 flights are operational weekly from San Francisco to Panama as of September 2025. The most popular departure day for this route is Mon, with 15% of flights per week taking off on this day.

Cheap San Francisco to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama

Best Price Found

Fastest flight time

Direct flights

Airports in Panama

When did momondo last update prices for flights from San Francisco Airport to Panama?

How many operators does momondo search for flights from San Francisco Airport to Panama?

How old do you have to be to fly from San Francisco Airport to Panama?

What documentation or ID do you need to fly to Panama?

What is the most popular plane model from San Francisco to Panama?

Best airlines flying from San Francisco to Panama

Compare and see reviews for airlines that fly from San Francisco to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama?

Can I find flights from San Francisco to Panama with flexible booking policies on momondo?

How can momondo help me find flights from San Francisco to Panama?

I’m not ready to book a flight from San Francisco to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo