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Cheap flights from San Francisco to Panama from $206

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Panama departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Panama

Cheap round-trip flights

Avianca Logo
12:05 am - 10:25 amSFO-PTY
8h 20m1 stop
Avianca Logo
10:05 pm - 12:35 pmPTY-SFO
16h 30m2 stops
$478Avianca
Find Deal
mar., sep. 23 - dom., sep. 28
Avianca Logo
2:20 pm - 4:30 pmSFO-PTY
24h 10m2 stops
Avianca Logo
3:40 pm - 10:45 pmPTY-SFO
9h 05m1 stop
$479Avianca
Find Deal
mié., sep. 3 - mar., sep. 16
Avianca Logo
12:05 am - 4:15 pmSFO-PTY
14h 10m1 stop
Avianca Logo
10:05 pm - 12:35 pmPTY-SFO
16h 30m2 stops
$481Avianca
Find Deal
mié., sep. 17 - jue., sep. 25
United Airlines Logo
12:43 am - 6:37 pmSFO-PTY
15h 54m1 stop
United Airlines Logo
3:35 pm - 8:29 pmPTY-SFO
7h 54mnonstop
$508United Airlines
Find Deal
mar., oct. 21 - mar., nov. 25
United Airlines Logo
10:55 am - 8:10 pmSFO-PTY
7h 15mnonstop
United Airlines Logo
3:35 pm - 9:10 pmPTY-SFO
7h 35mnonstop
$519United Airlines
Find Deal
sáb., sep. 6 - vie., sep. 19
American Airlines Logo
11:24 pm - 3:25 pmSFO-PTY
13h 01m2 stops
American Airlines Logo
4:15 pm - 11:07 amPTY-SFO
21h 52m2 stops
$528American Airlines
Find Deal
vie., dic. 5 - dom., dic. 14
Copa Airlines Logo
1:30 am - 5:32 pmSFO-DAV
14h 02m1 stop
Copa Airlines Logo
9:44 am - 11:39 pmDAV-SFO
15h 55m1 stop
$709Copa Airlines
Find Deal
lun., ago. 18 - jue., ago. 28
Copa Airlines Logo
1:30 am - 5:32 pmSFO-DAV
14h 02m1 stop
Copa Airlines Logo
8:41 am - 11:39 pmDAV-SFO
16h 58m1 stop
$969Copa Airlines
Find Deal
dom., ago. 10 - dom., ago. 17
Logo
12:05 am - 5:15 pmSFO-DAV
15h 10m2 stops
Logo
9:44 am - 11:39 pmDAV-SFO
15h 55m1 stop
$1,152
Find Deal
mar., ago. 12 - jue., ago. 14
Logo
2:20 pm - 8:00 amSFO-DAV
39h 40m2 stops
Logo
9:44 am - 11:39 pmDAV-SFO
15h 55m1 stop
$1,163
Find Deal
lun., ago. 11 - jue., ago. 14

Avianca flights from San Francisco to Panama

Our best Avianca deals on San Francisco to Panama flight tickets
Avianca
Sep 23
SFO12:05 amSan Francisco
8h 20m
1 stop
PTY10:25 amPanama City Tocumen Intl
Sep 28
PTY10:05 pmPanama City Tocumen Intl
16h 30m
2 stops
SFO12:35 pmSan Francisco
$478
Find similar
Avianca
Sep 3
SFO2:20 pmSan Francisco
24h 10m
2 stops
PTY4:30 pmPanama City Tocumen Intl
Sep 16
PTY3:40 pmPanama City Tocumen Intl
9h 05m
1 stop
SFO10:45 pmSan Francisco
$479
Find similar
Avianca
Sep 17
SFO12:05 amSan Francisco
14h 10m
1 stop
PTY4:15 pmPanama City Tocumen Intl
Sep 25
PTY10:05 pmPanama City Tocumen Intl
16h 30m
2 stops
SFO12:35 pmSan Francisco
$481
Find similar

United Airlines flights from San Francisco to Panama

Our best United Airlines deals on San Francisco to Panama flight tickets
United Airlines
Oct 21
SFO12:43 amSan Francisco
15h 54m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Nov 25
PTY3:35 pmPanama City Tocumen Intl
7h 54m
SFO8:29 pmSan Francisco
$508
Find similar
United Airlines
Sep 6
SFO10:55 amSan Francisco
7h 15m
PTY8:10 pmPanama City Tocumen Intl
Sep 19
PTY3:35 pmPanama City Tocumen Intl
7h 35m
SFO9:10 pmSan Francisco
$519
Find similar
United Airlines
Sep 2
SFO12:43 amSan Francisco
11h 31m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Sep 18
PTY3:35 pmPanama City Tocumen Intl
7h 35m
SFO9:10 pmSan Francisco
$523
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from San Francisco to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 9/23

12:05 am-10:25 am

1 stop8h 20m

Panama City Tocumen Intl

dom. 9/28

10:05 pm-12:35 pm

2 stops16h 30m

$478

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mié. 9/3

2:20 pm-4:30 pm

2 stops24h 10m

Panama City Tocumen Intl

mar. 9/16

3:40 pm-10:45 pm

1 stop9h 05m

$479

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mié. 9/17

12:05 am-4:15 pm

1 stop14h 10m

Panama City Tocumen Intl

jue. 9/25

10:05 pm-12:35 pm

2 stops16h 30m

$481

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

mar. 10/21

12:43 am-6:37 pm

1 stop15h 54m

Panama City Tocumen Intl

mar. 11/25

3:35 pm-8:29 pm

Nonstop7h 54m

$508

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

sáb. 9/6

10:55 am-8:10 pm

Nonstop7h 15m

Panama City Tocumen Intl

vie. 9/19

3:35 pm-9:10 pm

Nonstop7h 35m

$519

San FranciscoPanama City

SFO - PTY

SFOPTY

San Francisco

vie. 12/5

11:24 pm-3:25 pm

2 stops13h 01m

Panama City Tocumen Intl

dom. 12/14

4:15 pm-11:07 am

2 stops21h 52m

$528

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

lun. 8/18

1:30 am-5:32 pm

1 stop14h 02m

David Enrique Malek

jue. 8/28

9:44 am-11:39 pm

1 stop15h 55m

$709

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

dom. 8/10

1:30 am-5:32 pm

1 stop14h 02m

David Enrique Malek

dom. 8/17

8:41 am-11:39 pm

1 stop16h 58m

$969

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

mar. 8/12

12:05 am-5:15 pm

2 stops15h 10m

David Enrique Malek

jue. 8/14

9:44 am-11:39 pm

1 stop15h 55m

$1,152

San FranciscoDavid

SFO - DAV

SFODAV

San Francisco

lun. 8/11

2:20 pm-8:00 am

2 stops39h 40m

David Enrique Malek

jue. 8/14

9:44 am-11:39 pm

1 stop15h 55m

$1,163

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Francisco to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from San Francisco, with most prices found around $597. If you don’t want to visit Panama in August, then you should wait until September to fly from San Francisco, when ticket prices are also cheap, with an average price of $597.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from San Francisco. The lowest ticket price found for a Tuesday departure recently was $609. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Francisco to Panama for around $748.

What is the cheapest time of day to depart on your flight to Panama?

At noon is the cheapest time of day to fly from San Francisco to Panama when you can find flight prices for as low as $498. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $753 per ticket.

What is the cheapest San Francisco to Panama flight route?

Fly from San Francisco to Panama City Tocumen Intl for the best San Francisco - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $665 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Francisco for as low as $605 on momondo.

What cabin class options are available on San Francisco to Panama flights?

There are 3 cabin classes available to choose from on San Francisco to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Francisco to Panama flights?

You could potentially save up to 1% on your flight if you consider stops on a San Francisco to Panama flight.

Cheap San Francisco to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Panama

Best Price Found

$206

Fastest flight time

7h 15m

Direct flights

Every day

Airports in Panama

3 airports
The best one-way flight to Panama from San Francisco in the past 72 hours is $206. The best round-trip flight deal from San Francisco to Panama found on momondo in the last 72 hours is $478.
The fastest flight from San Francisco to Panama takes 7h 15m
Direct flights go from San Francisco to Panama every day.
There are 3 airports near Panama: Panama City Marcos A. Gelabert Intl (PAC), Panama City Tocumen Intl (PTY), David Enrique Malek (DAV)
Search flight deals

  • When did momondo last update prices for flights from San Francisco Airport to Panama?

    Prices for flights from San Francisco Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Panama?

  • How old do you have to be to fly from San Francisco Airport to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Francisco to Panama?

Best airlines flying from San Francisco to Panama

Compare and see reviews for airlines that fly from San Francisco to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $387Free CancellationRating
8.0
7,981 reviews
Search Delta flights
AviancaPriceFrom $400Free CancellationRating
6.7
2,388 reviews
Search Avianca flights
Copa AirlinesPriceFrom $503Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $539Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
American AirlinesPriceFrom $544Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Francisco to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Francisco to Panama with flexible booking policies on momondo?

Flights from San Francisco to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Panama?

momondo provides multiple filters to help you find the best flight to Panama from San Francisco. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from San Francisco to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for San Francisco to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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