Cheap flights from Los Angeles to Panama City from $176

In general, September is the cheapest month to fly from Los Angeles to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $519. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from Los Angeles to Panama City during August average around $521.

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $615. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $663. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Los Angeles to Panama City during this time can be as low as $616. Try not to purchase tickets in the evening because they tend to be around $635. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Los Angeles to Panama City Tocumen Intl for the best Los Angeles - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $628 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Los Angeles for as low as $581 on momondo.

There are 3 cabin classes available to choose from on Los Angeles to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 4% on your flight if you consider stops on a Los Angeles to Panama City flight.

As of February 2026, prices for Los Angeles to Panama City flights are approximately 44% more expensive when compared to flights at the same time last year.

Avianca is the most popular carrier operating from Los Angeles to Panama City Tocumen Intl

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Panama City from Los Angeles according to our data. Copa Airlines is the first choice among our users, with 78% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

San Salvador (SAL) was the most common stop: 46% of momondo users choosing 1-stop flights on this route connected there.

Flights via Miami (MIA) offer the lowest average round-trip price of $337.

Flights connecting via Houston (IAH) have the shortest average one-way travel time: 9h 43m.

San Salvador (SAL) has the shortest average layover time for this route: 2h 11m.

8 flights are operational daily from Los Angeles to Panama City as of February 2026. The most popular departure time for this route is 1:00AM, with 52% of flights per day taking off in the morning.

As of February 2026, 58 flights take off from Los Angeles and land in Panama City each week. The most common flight departure day for this route is Mon, with 16% of weekly flights taking off on this day.