Cheap flights from Los Angeles to Panama City from $320

In general, August is the cheapest month to fly from Los Angeles to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $599. If you’re not able to fly to Panama City in August, then February is your next best option. Flight prices from Los Angeles to Panama City during February average around $628.

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $636. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $680. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Los Angeles to Panama City during this time can be as low as $647. Try not to purchase tickets in the evening because they tend to be around $662. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Los Angeles to Panama City Tocumen Intl for the best Los Angeles - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $691 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Los Angeles for as low as $595 on momondo.

There are 3 cabin classes available to choose from on Los Angeles to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Los Angeles to Panama City.

As of July 2026, prices for Los Angeles to Panama City flights are approximately 2% more expensive when compared to flights at the same time last year.

United Airlines and Copa Airlines are the most popular carriers operating from Los Angeles to Panama City Tocumen Intl

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Panama City from Los Angeles according to our data. Copa Airlines is the first choice among our users, with 77% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Houston (IAH) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Mexico City (MEX) offer the lowest average round-trip price of $784.

Flights connecting via San Salvador (SAL) have the shortest average one-way travel time: 9h 06m.

San Salvador (SAL) has the shortest average layover time for this route: 1h 51m.

9 flights are operational daily from Los Angeles to Panama City as of July 2026. The most popular departure time for this route is 1:00AM, with 53% of flights per day taking off in the morning.

As of July 2026, 64 flights take off from Los Angeles and land in Panama City each week. The most common flight departure day for this route is Tue, with 16% of weekly flights taking off on this day.