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Cheap flights from Washington, D.C. Reagan-National Airport to Knoxville from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Knoxville departing on 7/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Washington, D.C. Reagan-National Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:45 pm - 9:31 pm
DCA
-
TYS
1h 46mnonstop
American Airlines Logo
7:32 am - 9:19 am
TYS
-
DCA
1h 47mnonstop
$187American Airlines
Tue, Jun 23 - Tue, Jun 30
American Airlines Logo
4:59 pm - 6:46 pm
DCA
-
TYS
1h 47mnonstop
American Airlines Logo
7:06 am - 8:59 am
TYS
-
DCA
1h 53mnonstop
$200American Airlines
Tue, Aug 11 - Sat, Aug 15
Delta Logo
6:00 am - 9:38 am
DCA
-
TYS
3h 38m
1 stop
Delta Logo
5:40 am - 9:15 am
TYS
-
DCA
3h 35m
1 stop
$207Delta
Tue, Jun 23 - Tue, Jun 30
American Airlines Logo
9:00 am - 10:48 am
DCA
-
TYS
1h 48mnonstop
American Airlines Logo
11:18 am - 12:59 pm
TYS
-
DCA
1h 41mnonstop
$212American Airlines
Tue, Jun 16 - Sat, Jun 20
American Airlines Logo
7:07 pm - 11:47 pm
DCA
-
TYS
4h 40m
1 stop
American Airlines Logo
7:32 am - 9:19 am
TYS
-
DCA
1h 47mnonstop
$222American Airlines
Tue, Jun 23 - Tue, Jun 30
Southwest Logo
6:10 am - 12:05 pm
DCA
-
TYS
5h 55m
1 stop
Southwest Logo
7:45 pm - 11:20 pm
TYS
-
DCA
3h 35m
1 stop
$232Southwest
Tue, Jul 14 - Fri, Jul 17
American Airlines Logo
5:00 am - 8:38 am
DCA
-
TYS
3h 38m
1 stop
American Airlines Logo
7:04 am - 8:57 am
TYS
-
DCA
1h 53mnonstop
$235American Airlines
Sat, Aug 8 - Sat, Aug 15
American Airlines Logo
7:46 pm - 9:33 pm
DCA
-
TYS
1h 47mnonstop
American Airlines Logo
7:07 am - 8:57 am
TYS
-
DCA
1h 50mnonstop
$237American Airlines
Mon, Jul 27 - Sat, Aug 1
Southwest Logo
6:00 am - 5:10 pm
DCA
-
TYS
11h 10m
1 stop
Southwest Logo
7:00 am - 12:05 pm
TYS
-
DCA
5h 05m
1 stop
$238Southwest
Thu, Sep 3 - Tue, Sep 8
American Airlines Logo
7:45 pm - 9:31 pm
DCA
-
TYS
1h 46mnonstop
American Airlines Logo
7:32 am - 9:19 am
TYS
-
DCA
1h 47mnonstop
$242American Airlines
Fri, Jun 19 - Tue, Jun 23

Southwest flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best Southwest deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
Southwest
Jul 14
DCA6:10 amWashington, D.C. Reagan-National
5h 55m
1 stop
TYS12:05 pmKnoxville McGhee Tyson
Jul 17
TYS7:45 pmKnoxville McGhee Tyson
3h 35m
1 stop
DCA11:20 pmWashington, D.C. Reagan-National
$232
Southwest
Sep 3
DCA6:00 amWashington, D.C. Reagan-National
11h 10m
1 stop
TYS5:10 pmKnoxville McGhee Tyson
Sep 8
TYS7:00 amKnoxville McGhee Tyson
5h 05m
1 stop
DCA12:05 pmWashington, D.C. Reagan-National
$238
Southwest
Sep 3
DCA6:00 amWashington, D.C. Reagan-National
11h 10m
1 stop
TYS5:10 pmKnoxville McGhee Tyson
Sep 8
TYS7:00 amKnoxville McGhee Tyson
8h 45m
2 stops
DCA3:45 pmWashington, D.C. Reagan-National
$244

Delta flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best Delta deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
Delta
Jun 23
DCA6:00 amWashington, D.C. Reagan-National
3h 38m
1 stop
TYS9:38 amKnoxville McGhee Tyson
Jun 30
TYS5:40 amKnoxville McGhee Tyson
3h 35m
1 stop
DCA9:15 amWashington, D.C. Reagan-National
$207
Delta
Nov 6
DCA7:30 pmWashington, D.C. Reagan-National
4h 16m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Nov 11
TYS2:30 pmKnoxville McGhee Tyson
6h 45m
1 stop
DCA9:15 pmWashington, D.C. Reagan-National
$253
Delta
Jul 14
DCA6:59 amWashington, D.C. Reagan-National
4h 06m
1 stop
TYS11:05 amKnoxville McGhee Tyson
Jul 19
TYS5:40 amKnoxville McGhee Tyson
3h 36m
1 stop
DCA9:16 amWashington, D.C. Reagan-National
$283

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 6/23

7:45 pm-9:31 pm

Nonstop1h 46m

Knoxville McGhee Tyson

Tue 6/30

7:32 am-9:19 am

Nonstop1h 47m

$187

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 8/11

4:59 pm-6:46 pm

Nonstop1h 47m

Knoxville McGhee Tyson

Sat 8/15

7:06 am-8:59 am

Nonstop1h 53m

$200

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 6/23

6:00 am-9:38 am

1 stop3h 38m

Knoxville McGhee Tyson

Tue 6/30

5:40 am-9:15 am

1 stop3h 35m

$207
Quickest round-trip

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 6/16

9:00 am-10:48 am

Nonstop1h 48m

Knoxville McGhee Tyson

Sat 6/20

11:18 am-12:59 pm

Nonstop1h 41m

$212

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 6/23

7:07 pm-11:47 pm

1 stop4h 40m

Knoxville McGhee Tyson

Tue 6/30

7:32 am-9:19 am

Nonstop1h 47m

$222

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Tue 7/14

6:10 am-12:05 pm

1 stop5h 55m

Knoxville McGhee Tyson

Fri 7/17

7:45 pm-11:20 pm

1 stop3h 35m

$232

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 8/8

5:00 am-8:38 am

1 stop3h 38m

Knoxville McGhee Tyson

Sat 8/15

7:04 am-8:57 am

Nonstop1h 53m

$235

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Mon 7/27

7:46 pm-9:33 pm

Nonstop1h 47m

Knoxville McGhee Tyson

Sat 8/1

7:07 am-8:57 am

Nonstop1h 50m

$237

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 9/3

6:00 am-5:10 pm

1 stop11h 10m

Knoxville McGhee Tyson

Tue 9/8

7:00 am-12:05 pm

1 stop5h 05m

$238

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Fri 6/19

7:45 pm-9:31 pm

Nonstop1h 46m

Knoxville McGhee Tyson

Tue 6/23

7:32 am-9:19 am

Nonstop1h 47m

$242

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Knoxville from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Washington, D.C. Reagan-National Airport and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Washington, D.C. Reagan-National Airport, with most prices found around $201. If you aren’t able to travel during the month of January, then book flights to Knoxville from Washington, D.C. Reagan-National Airport during June instead. Flights to Knoxville in June, while not as cheap as those in January, still average around $263.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Washington, D.C. Reagan-National Airport to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $264. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Washington, D.C. Reagan-National Airport to Knoxville for around $334.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Washington, D.C. Reagan-National Airport to Knoxville when you can find flight prices for as low as $188. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $326.

What is the cheapest Washington, D.C. Reagan-National to Knoxville McGhee Tyson flight route?

Fly from Washington, D.C. Reagan-National to Knoxville McGhee Tyson for the best Washington, D.C. Reagan-National - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight from Washington, D.C. Reagan-National Airport to Knoxville?

You are more likely to see cheaper flights to Knoxville from Washington, D.C. Reagan-National Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $323 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Washington, D.C. Reagan-National Airport for as low as $189 on momondo.

What cabin class options are available on Washington, D.C. Reagan-National Airport to Knoxville flights?

There is only 1 cabin class available to choose from on Washington, D.C. Reagan-National Airport to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Washington, D.C. Reagan-National Airport to Knoxville flights?

You could potentially save up to 5% on your flight if you consider stops on a Washington, D.C. Reagan-National Airport to Knoxville flight.

How have Washington, D.C. Reagan-National Airport to Knoxville flight prices changed over time?

As of May 2026, prices for Washington, D.C. Reagan-National Airport to Knoxville flights are approximately 86% more expensive when compared to flights at the same time last year.

When to book flights from Washington, D.C. Reagan-National Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Knoxville (DCA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Knoxville

Best Price Found

$297

Fastest flight time

1h 41m

Direct flights

Every day

Airports in Knoxville

1 airport
The best flight deal from Washington, D.C. Reagan-National Airport to Knoxville found on momondo in the last 72 hours is $297
The fastest flight from Washington, D.C. Reagan-National Airport to Knoxville takes 1h 41m
Direct flights go from Washington, D.C. Reagan-National Airport to Knoxville every day.
There is 1 airport in Knoxville. From Washington, D.C. Reagan-National Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Washington, D.C. Reagan-National Airport to Knoxville

  • How far is Washington, D.C. Reagan-National to Knoxville McGhee Tyson by plane?

    There are 426.9 mi between Washington, D.C. Reagan-National and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 1h 41m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Washington, D.C. Reagan-National Airport to Knoxville?

  • What is the most popular airline from Washington, D.C. Reagan-National Airport to Knoxville?

Best airlines flying from Washington, D.C. Reagan-National Airport to Knoxville

Compare and see reviews for airlines that fly from Washington, D.C. Reagan-National Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.1
11,630 reviews
Search American Airlines flights

  • American Airlines Flights From Washington, D.C. Reagan-National Airport to Knoxville

    American Airlines flies from Washington, D.C. Reagan-National Airport to Knoxville around 7 times per week, with 11,630 momondo users rating the airline 7.1/10. The cheapest American Airlines deal from Washington, D.C. Reagan-National Airport to Knoxville in the last 72 hours was $189 (round-trip), much lower than the average airfare cost of $330 for American Airlines flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Lenoir City
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Knoxville?

Finding the right flight to Knoxville from Washington, D.C. is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Washington, D.C. to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Washington, D.C. on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Washington, D.C. to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Washington, D.C. to Knoxville.

I’m not ready to book a flight from Washington, D.C. to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Washington, D.C. are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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