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Cheap flights from Washington, D.C. Reagan-National Airport to Knoxville from $55

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Knoxville departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Washington, D.C. Reagan-National Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:00 pm - 3:57 pmDCA-TYS
21h 57m1 stop
Frontier Logo
4:52 pm - 1:06 pmTYS-DCA
20h 14m1 stop
$121Frontier
Find Deal
sáb., dic. 6 - lun., dic. 8
American Airlines Logo
1:59 pm - 3:56 pmDCA-TYS
1h 57mnonstop
American Airlines Logo
4:15 pm - 5:59 pmTYS-DCA
1h 44mnonstop
$189American Airlines
Find Deal
mié., feb. 11 - lun., feb. 23
Delta Logo
7:36 pm - 11:28 pmDCA-TYS
3h 52m1 stop
Delta Logo
7:59 pm - 11:40 pmTYS-DCA
3h 41m1 stop
$209Delta
Find Deal
vie., dic. 5 - lun., dic. 8
American Airlines Logo
1:59 pm - 3:48 pmDCA-TYS
1h 49mnonstop
American Airlines Logo
5:03 pm - 6:44 pmTYS-DCA
1h 41mnonstop
$219American Airlines
Find Deal
jue., nov. 20 - dom., nov. 23
American Airlines Logo
4:43 pm - 8:56 pmDCA-TYS
4h 13m1 stop
American Airlines Logo
4:15 pm - 5:59 pmTYS-DCA
1h 44mnonstop
$220American Airlines
Find Deal
mié., feb. 11 - lun., feb. 23
Frontier Logo
8:00 am - 3:57 pmDCA-TYS
7h 57m1 stop
Frontier Logo
4:52 pm - 1:06 pmTYS-DCA
20h 14m1 stop
$222Frontier
Find Deal
dom., dic. 14 - lun., dic. 15
American Airlines Logo
9:03 am - 10:50 amDCA-TYS
1h 47mnonstop
American Airlines Logo
4:32 pm - 6:10 pmTYS-DCA
1h 38mnonstop
$231American Airlines
Find Deal
mar., dic. 9 - mar., dic. 9
American Airlines Logo
1:41 pm - 8:53 pmDCA-TYS
7h 12m1 stop
American Airlines Logo
6:00 am - 7:48 amTYS-DCA
1h 48mnonstop
$233American Airlines
Find Deal
vie., dic. 5 - lun., dic. 8
American Airlines Logo
7:48 pm - 9:36 pmDCA-TYS
1h 48mnonstop
American Airlines Logo
6:00 am - 7:48 amTYS-DCA
1h 48mnonstop
$234American Airlines
Find Deal
vie., dic. 5 - lun., dic. 8
Delta Logo
6:59 am - 1:44 pmDCA-TYS
6h 45m1 stop
Delta Logo
5:35 am - 11:39 amTYS-DCA
6h 04m1 stop
$239Delta
Find Deal
mar., nov. 18 - dom., nov. 23

American Airlines flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best American Airlines deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
American Airlines
Feb 11
DCA1:59 pmWashington, D.C. Reagan-National
1h 57m
TYS3:56 pmKnoxville McGhee Tyson
Feb 23
TYS4:15 pmKnoxville McGhee Tyson
1h 44m
DCA5:59 pmWashington, D.C. Reagan-National
$189
Find similar
American Airlines
Nov 20
DCA1:59 pmWashington, D.C. Reagan-National
1h 49m
TYS3:48 pmKnoxville McGhee Tyson
Nov 23
TYS5:03 pmKnoxville McGhee Tyson
1h 41m
DCA6:44 pmWashington, D.C. Reagan-National
$219
Find similar
American Airlines
Feb 11
DCA4:43 pmWashington, D.C. Reagan-National
4h 13m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
Feb 23
TYS4:15 pmKnoxville McGhee Tyson
1h 44m
DCA5:59 pmWashington, D.C. Reagan-National
$220
Find similar

Frontier flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best Frontier deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
Frontier
Dec 6
DCA6:00 pmWashington, D.C. Reagan-National
21h 57m
1 stop
TYS3:57 pmKnoxville McGhee Tyson
Dec 8
TYS4:52 pmKnoxville McGhee Tyson
20h 14m
1 stop
DCA1:06 pmWashington, D.C. Reagan-National
$121
Find similar
Frontier
Dec 14
DCA8:00 amWashington, D.C. Reagan-National
7h 57m
1 stop
TYS3:57 pmKnoxville McGhee Tyson
Dec 15
TYS4:52 pmKnoxville McGhee Tyson
20h 14m
1 stop
DCA1:06 pmWashington, D.C. Reagan-National
$222
Find similar
Frontier
Dec 11
DCA8:00 amWashington, D.C. Reagan-National
7h 57m
1 stop
TYS3:57 pmKnoxville McGhee Tyson
Dec 15
TYS4:52 pmKnoxville McGhee Tyson
20h 14m
1 stop
DCA1:06 pmWashington, D.C. Reagan-National
$345
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

sáb. 12/6

6:00 pm-3:57 pm

1 stop21h 57m

Knoxville McGhee Tyson

lun. 12/8

4:52 pm-1:06 pm

1 stop20h 14m

$121

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

mié. 2/11

1:59 pm-3:56 pm

Nonstop1h 57m

Knoxville McGhee Tyson

lun. 2/23

4:15 pm-5:59 pm

Nonstop1h 44m

$189

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

vie. 12/5

7:36 pm-11:28 pm

1 stop3h 52m

Knoxville McGhee Tyson

lun. 12/8

7:59 pm-11:40 pm

1 stop3h 41m

$209

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

jue. 11/20

1:59 pm-3:48 pm

Nonstop1h 49m

Knoxville McGhee Tyson

dom. 11/23

5:03 pm-6:44 pm

Nonstop1h 41m

$219

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

mié. 2/11

4:43 pm-8:56 pm

1 stop4h 13m

Knoxville McGhee Tyson

lun. 2/23

4:15 pm-5:59 pm

Nonstop1h 44m

$220

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

dom. 12/14

8:00 am-3:57 pm

1 stop7h 57m

Knoxville McGhee Tyson

lun. 12/15

4:52 pm-1:06 pm

1 stop20h 14m

$222

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

mar. 12/9

9:03 am-10:50 am

Nonstop1h 47m

Knoxville McGhee Tyson

mar. 12/9

4:32 pm-6:10 pm

Nonstop1h 38m

$231

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

vie. 12/5

1:41 pm-8:53 pm

1 stop7h 12m

Knoxville McGhee Tyson

lun. 12/8

6:00 am-7:48 am

Nonstop1h 48m

$233

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

vie. 12/5

7:48 pm-9:36 pm

Nonstop1h 48m

Knoxville McGhee Tyson

lun. 12/8

6:00 am-7:48 am

Nonstop1h 48m

$234

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

mar. 11/18

6:59 am-1:44 pm

1 stop6h 45m

Knoxville McGhee Tyson

dom. 11/23

5:35 am-11:39 am

1 stop6h 04m

$239

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Knoxville from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Washington, D.C. Reagan-National Airport, with most prices found around $261. If you aren’t able to travel during the month of January, then book flights to Knoxville from Washington, D.C. Reagan-National Airport during February instead. Flights to Knoxville in February, while not as cheap as those in January, still average around $264.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Washington, D.C. Reagan-National Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $289. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Washington, D.C. Reagan-National Airport to Knoxville for around $376.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Washington, D.C. Reagan-National Airport to Knoxville when you can find flight prices for as low as $249. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $331.

What is the cheapest Washington, D.C. Reagan-National to Knoxville McGhee Tyson flight route?

Fly from Washington, D.C. Reagan-National to Knoxville McGhee Tyson for the best Washington, D.C. Reagan-National - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Washington, D.C. Reagan-National Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $312 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Washington, D.C. Reagan-National Airport for as low as $142 on momondo.

What cabin class options are available on Washington, D.C. Reagan-National to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Washington, D.C. Reagan-National to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Washington, D.C. Reagan-National Airport to Knoxville flight prices changed over time?

As of November 2025, prices for Washington, D.C. Reagan-National Airport to Knoxville flights are approximately 33% more expensive when compared to flights at the same time last year.

When to book flights from Washington, D.C. Reagan-National Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Knoxville (DCA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Knoxville

Best Price Found

$168

Fastest flight time

1h 44m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Washington, D.C. Reagan-National Airport in the past 72 hours is $168. The best round-trip flight deal from Washington, D.C. Reagan-National Airport to Knoxville found on momondo in the last 72 hours is $274.
The fastest flight from Washington, D.C. Reagan-National Airport to Knoxville takes 1h 44m
Direct flights go from Washington, D.C. Reagan-National Airport to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Washington, D.C. Reagan-National to Knoxville McGhee Tyson by plane?

    There are 426.9 mi between Washington, D.C. Reagan-National and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 1h 45m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Washington, D.C. Reagan-National Airport to Knoxville?

  • What is the most popular airline from Washington, D.C. Reagan-National Airport to Knoxville?

Best airlines flying from Washington, D.C. Reagan-National Airport to Knoxville

Compare and see reviews for airlines that fly from Washington, D.C. Reagan-National Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights

  • American Airlines Flights From Washington, D.C. Reagan-National Airport to Knoxville

    American Airlines flies from Washington, D.C. Reagan-National Airport to Knoxville around 16 times per week, with 11,040 momondo users rating the airline 7.2/10. The cheapest American Airlines deal from Washington, D.C. Reagan-National Airport to Knoxville in the last 72 hours was $189 (round-trip), much lower than the average airfare cost of $319 for American Airlines flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Knoxville?

Finding the right flight to Knoxville from Washington, D.C. is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Washington, D.C. to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Washington, D.C. on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Washington, D.C. to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Washington, D.C. to Knoxville.

I’m not ready to book a flight from Washington, D.C. to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Washington, D.C. are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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