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Cheap flights from Washington, D.C. Reagan-National Airport to Knoxville from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Knoxville departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Washington, D.C. Reagan-National Airport to Knoxville

Cheap round-trip flights

American Airlines Logo
7:58 pm - 9:41 pmDCA-TYS
1h 43mnonstop
American Airlines Logo
6:25 am - 8:14 amTYS-DCA
1h 49mnonstop
$189American Airlines
Find Deal
Wed, Sep 24 - Sat, Sep 27
American Airlines Logo
1:55 pm - 3:41 pmDCA-TYS
1h 46mnonstop
American Airlines Logo
5:20 pm - 6:59 pmTYS-DCA
1h 39mnonstop
$194American Airlines
Find Deal
Sat, Sep 20 - Tue, Sep 30
Delta Logo
7:30 pm - 11:44 pmDCA-TYS
4h 14m1 stop
Delta Logo
8:10 pm - 11:41 pmTYS-DCA
3h 31m1 stop
$209Delta
Find Deal
Fri, Oct 3 - Mon, Oct 6
American Airlines Logo
1:59 pm - 3:48 pmDCA-TYS
1h 49mnonstop
American Airlines Logo
6:06 am - 7:49 amTYS-DCA
1h 43mnonstop
$219American Airlines
Find Deal
Thu, Nov 20 - Sun, Nov 23
American Airlines Logo
1:55 pm - 3:41 pmDCA-TYS
1h 46mnonstop
American Airlines Logo
6:25 am - 8:14 amTYS-DCA
1h 49mnonstop
$224American Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
Delta Logo
6:00 am - 10:39 amDCA-TYS
4h 39m1 stop
Delta Logo
8:10 pm - 11:41 pmTYS-DCA
3h 31m1 stop
$234Delta
Find Deal
Thu, Oct 2 - Mon, Oct 6
Frontier Logo
6:00 pm - 4:18 pmDCA-TYS
22h 18m1 stop
Frontier Logo
8:35 pm - 9:59 pmTYS-DCA
25h 24m1 stop
$264Frontier
Find Deal
Sat, Sep 13 - Mon, Sep 15
Frontier Logo
7:00 am - 6:22 pmDCA-TYS
11h 22m1 stop
Frontier Logo
7:17 pm - 5:01 pmTYS-DCA
21h 44m1 stop
$266Frontier
Find Deal
Thu, Nov 13 - Sun, Nov 16
Logo
8:00 am - 7:32 pmDCA-TYS
11h 32m1 stop
Logo
1:23 pm - 9:59 pmTYS-DCA
32h 36m2 stops
$319
Find Deal
Mon, Oct 27 - Mon, Nov 3
Logo
8:00 am - 7:32 pmDCA-TYS
11h 32m1 stop
Logo
5:44 pm - 4:59 pmTYS-DCA
23h 15m2 stops
$341
Find Deal
Mon, Oct 27 - Fri, Oct 31

Delta flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best Delta deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
Delta
Oct 3
DCA7:30 pmWashington, D.C. Reagan-National
4h 14m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Oct 6
TYS8:10 pmKnoxville McGhee Tyson
3h 31m
1 stop
DCA11:41 pmWashington, D.C. Reagan-National
$209
Find similar
Delta
Oct 2
DCA6:00 amWashington, D.C. Reagan-National
4h 39m
1 stop
TYS10:39 amKnoxville McGhee Tyson
Oct 6
TYS8:10 pmKnoxville McGhee Tyson
3h 31m
1 stop
DCA11:41 pmWashington, D.C. Reagan-National
$234
Find similar
Delta
Sep 13
DCA12:30 pmWashington, D.C. Reagan-National
5h 53m
1 stop
TYS6:23 pmKnoxville McGhee Tyson
Sep 20
TYS6:08 pmKnoxville McGhee Tyson
5h 34m
1 stop
DCA11:42 pmWashington, D.C. Reagan-National
$244
Find similar

American Airlines flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best American Airlines deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
American Airlines
Sep 24
DCA7:58 pmWashington, D.C. Reagan-National
1h 43m
TYS9:41 pmKnoxville McGhee Tyson
Sep 27
TYS6:25 amKnoxville McGhee Tyson
1h 49m
DCA8:14 amWashington, D.C. Reagan-National
$189
Find similar
American Airlines
Sep 20
DCA1:55 pmWashington, D.C. Reagan-National
1h 46m
TYS3:41 pmKnoxville McGhee Tyson
Sep 30
TYS5:20 pmKnoxville McGhee Tyson
1h 39m
DCA6:59 pmWashington, D.C. Reagan-National
$194
Find similar
American Airlines
Nov 20
DCA1:59 pmWashington, D.C. Reagan-National
1h 49m
TYS3:48 pmKnoxville McGhee Tyson
Nov 23
TYS6:06 amKnoxville McGhee Tyson
1h 43m
DCA7:49 amWashington, D.C. Reagan-National
$219
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 4, 2025.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Wed 9/24

7:58 pm-9:41 pm

Nonstop1h 43m

Knoxville McGhee Tyson

Sat 9/27

6:25 am-8:14 am

Nonstop1h 49m

$189

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 9/20

1:55 pm-3:41 pm

Nonstop1h 46m

Knoxville McGhee Tyson

Tue 9/30

5:20 pm-6:59 pm

Nonstop1h 39m

$194

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Fri 10/3

7:30 pm-11:44 pm

1 stop4h 14m

Knoxville McGhee Tyson

Mon 10/6

8:10 pm-11:41 pm

1 stop3h 31m

$209

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 11/20

1:59 pm-3:48 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Sun 11/23

6:06 am-7:49 am

Nonstop1h 43m

$219

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 9/13

1:55 pm-3:41 pm

Nonstop1h 46m

Knoxville McGhee Tyson

Sat 9/20

6:25 am-8:14 am

Nonstop1h 49m

$224

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 10/2

6:00 am-10:39 am

1 stop4h 39m

Knoxville McGhee Tyson

Mon 10/6

8:10 pm-11:41 pm

1 stop3h 31m

$234

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 9/13

6:00 pm-4:18 pm

1 stop22h 18m

Knoxville McGhee Tyson

Mon 9/15

8:35 pm-9:59 pm

1 stop25h 24m

$264

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 11/13

7:00 am-6:22 pm

1 stop11h 22m

Knoxville McGhee Tyson

Sun 11/16

7:17 pm-5:01 pm

1 stop21h 44m

$266

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Mon 10/27

8:00 am-7:32 pm

1 stop11h 32m

Knoxville McGhee Tyson

Mon 11/3

1:23 pm-9:59 pm

2 stops32h 36m

$319

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Mon 10/27

8:00 am-7:32 pm

1 stop11h 32m

Knoxville McGhee Tyson

Fri 10/31

5:44 pm-4:59 pm

2 stops23h 15m

$341

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Washington, D.C. Reagan-National Airport, with most prices found around $261. If you aren’t able to travel during the month of January, then book flights to Knoxville from Washington, D.C. Reagan-National Airport during February instead. Flights to Knoxville in February, while not as cheap as those in January, still average around $264.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Washington, D.C. Reagan-National Airport to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $290. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Washington, D.C. Reagan-National Airport to Knoxville for around $377.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Washington, D.C. Reagan-National Airport to Knoxville when you can find flight prices for as low as $249. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $343.

What is the cheapest Washington, D.C. Reagan-National to Knoxville McGhee Tyson flight route?

Fly from Washington, D.C. Reagan-National to Knoxville McGhee Tyson for the best Washington, D.C. Reagan-National - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Washington, D.C. Reagan-National Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $316 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Washington, D.C. Reagan-National Airport for as low as $241 on momondo.

What cabin class options are available on Washington, D.C. Reagan-National to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Washington, D.C. Reagan-National to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Washington, D.C. Reagan-National Airport to Knoxville flight prices changed over time?

As of September 2025, prices for Washington, D.C. Reagan-National Airport to Knoxville flights are approximately 11% more expensive when compared to flights at the same time last year.

When to book flights from Washington, D.C. Reagan-National Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Knoxville (DCA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Knoxville

Best Price Found

$213

Fastest flight time

1h 39m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Washington, D.C. Reagan-National Airport in the past 72 hours is $213. The best round-trip flight deal from Washington, D.C. Reagan-National Airport to Knoxville found on momondo in the last 72 hours is $254.
The fastest flight from Washington, D.C. Reagan-National Airport to Knoxville takes 1h 39m
Direct flights go from Washington, D.C. Reagan-National Airport to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Washington, D.C. Reagan-National to Knoxville McGhee Tyson by plane?

    There are 426.9 mi between Washington, D.C. Reagan-National and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 1h 41m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Washington, D.C. Reagan-National Airport to Knoxville?

  • What is the most popular airline from Washington, D.C. Reagan-National Airport to Knoxville?

Best airlines flying from Washington, D.C. Reagan-National Airport to Knoxville

Compare and see reviews for airlines that fly from Washington, D.C. Reagan-National Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $202Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • American Airlines Flights From Washington, D.C. Reagan-National Airport to Knoxville

    American Airlines flies from Washington, D.C. Reagan-National Airport to Knoxville around 19 times per week, with 10,000 momondo users rating the airline 7.2/10. The cheapest American Airlines deal from Washington, D.C. Reagan-National Airport to Knoxville in the last 72 hours was $202 (round-trip), much lower than the average airfare cost of $320 for American Airlines flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Newport
Alcoa
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Knoxville?

Finding the right flight to Knoxville from Washington, D.C. is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Washington, D.C. to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Washington, D.C. on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Washington, D.C. to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Washington, D.C. to Knoxville.

I’m not ready to book a flight from Washington, D.C. to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Washington, D.C. are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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