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Cheap flights from Washington, D.C. Reagan-National Airport to Knoxville from $86

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Knoxville departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Washington, D.C. Reagan-National Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:47 pm - 9:44 pm
DCA
-
TYS
1h 57mnonstop
American Airlines Logo
6:05 am - 7:47 am
TYS
-
DCA
1h 42mnonstop
$176American Airlines
Wed, Feb 11 - Sun, Feb 15
Frontier Logo
2:00 pm - 3:30 pm
DCA
-
TYS
25h 30m
1 stop
Frontier Logo
4:30 pm - 1:15 pm
TYS
-
DCA
20h 45m
1 stop
$179Frontier
Thu, Feb 5 - Mon, Feb 9
American Airlines Logo
1:44 pm - 3:32 pm
DCA
-
TYS
1h 48mnonstop
American Airlines Logo
6:05 am - 7:47 am
TYS
-
DCA
1h 42mnonstop
$183American Airlines
Thu, Feb 19 - Thu, Feb 26
American Airlines Logo
1:44 pm - 3:32 pm
DCA
-
TYS
1h 48mnonstop
American Airlines Logo
6:05 am - 7:47 am
TYS
-
DCA
1h 42mnonstop
$186American Airlines
Thu, Feb 26 - Sun, Mar 1
American Airlines Logo
9:04 am - 10:48 am
DCA
-
TYS
1h 44mnonstop
American Airlines Logo
6:41 pm - 8:22 pm
TYS
-
DCA
1h 41mnonstop
$189American Airlines
Sat, May 23 - Sat, May 30
Frontier Logo
8:00 am - 7:18 pm
DCA
-
TYS
11h 18m
1 stop
Frontier Logo
8:13 pm - 1:15 pm
TYS
-
DCA
17h 02m
1 stop
$200Frontier
Mon, Feb 16 - Mon, Feb 23
American Airlines Logo
8:47 am - 10:49 am
DCA
-
TYS
2h 02mnonstop
American Airlines Logo
6:00 am - 7:46 am
TYS
-
DCA
1h 46mnonstop
$201American Airlines
Fri, Feb 6 - Mon, Feb 9
Frontier Logo
8:00 am - 7:27 pm
DCA
-
TYS
11h 27m
1 stop
Frontier Logo
8:13 pm - 1:15 pm
TYS
-
DCA
17h 02m
1 stop
$207Frontier
Fri, Feb 20 - Mon, Feb 23
Delta Logo
1:45 pm - 6:17 pm
DCA
-
TYS
4h 32m
1 stop
Delta Logo
7:20 pm - 11:23 pm
TYS
-
DCA
4h 03m
1 stop
$213Delta
Sat, Jul 18 - Mon, Jul 20
American Airlines Logo
8:47 am - 10:49 am
DCA
-
TYS
2h 02mnonstop
American Airlines Logo
6:00 am - 7:46 am
TYS
-
DCA
1h 46mnonstop
$219American Airlines
Thu, Feb 5 - Mon, Feb 9

Delta flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best Delta deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
Delta
Jul 18
DCA1:45 pmWashington, D.C. Reagan-National
4h 32m
1 stop
TYS6:17 pmKnoxville McGhee Tyson
Jul 20
TYS7:20 pmKnoxville McGhee Tyson
4h 03m
1 stop
DCA11:23 pmWashington, D.C. Reagan-National
$213
Delta
Feb 11
DCA9:00 amWashington, D.C. Reagan-National
6h 21m
1 stop
TYS3:21 pmKnoxville McGhee Tyson
Feb 23
TYS6:41 pmKnoxville McGhee Tyson
4h 51m
1 stop
DCA11:32 pmWashington, D.C. Reagan-National
$241
Delta
May 23
DCA8:00 amWashington, D.C. Reagan-National
5h 25m
1 stop
TYS1:25 pmKnoxville McGhee Tyson
May 27
TYS4:15 pmKnoxville McGhee Tyson
5h 04m
1 stop
DCA9:19 pmWashington, D.C. Reagan-National
$244

Frontier flights from Washington, D.C. Reagan-National Airport to Knoxville

Our best Frontier deals on Washington, D.C. Reagan-National Airport to Knoxville flight tickets
Frontier
Feb 5
DCA2:00 pmWashington, D.C. Reagan-National
25h 30m
1 stop
TYS3:30 pmKnoxville McGhee Tyson
Feb 9
TYS4:30 pmKnoxville McGhee Tyson
20h 45m
1 stop
DCA1:15 pmWashington, D.C. Reagan-National
$179
Frontier
Feb 16
DCA8:00 amWashington, D.C. Reagan-National
11h 18m
1 stop
TYS7:18 pmKnoxville McGhee Tyson
Feb 23
TYS8:13 pmKnoxville McGhee Tyson
17h 02m
1 stop
DCA1:15 pmWashington, D.C. Reagan-National
$200
Frontier
Feb 20
DCA8:00 amWashington, D.C. Reagan-National
11h 27m
1 stop
TYS7:27 pmKnoxville McGhee Tyson
Feb 23
TYS8:13 pmKnoxville McGhee Tyson
17h 02m
1 stop
DCA1:15 pmWashington, D.C. Reagan-National
$207

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Wed 2/11

7:47 pm-9:44 pm

Nonstop1h 57m

Knoxville McGhee Tyson

Sun 2/15

6:05 am-7:47 am

Nonstop1h 42m

$176

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 2/5

2:00 pm-3:30 pm

1 stop25h 30m

Knoxville McGhee Tyson

Mon 2/9

4:30 pm-1:15 pm

1 stop20h 45m

$179

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 2/19

1:44 pm-3:32 pm

Nonstop1h 48m

Knoxville McGhee Tyson

Thu 2/26

6:05 am-7:47 am

Nonstop1h 42m

$183

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 2/26

1:44 pm-3:32 pm

Nonstop1h 48m

Knoxville McGhee Tyson

Sun 3/1

6:05 am-7:47 am

Nonstop1h 42m

$186

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 5/23

9:04 am-10:48 am

Nonstop1h 44m

Knoxville McGhee Tyson

Sat 5/30

6:41 pm-8:22 pm

Nonstop1h 41m

$189

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Mon 2/16

8:00 am-7:18 pm

1 stop11h 18m

Knoxville McGhee Tyson

Mon 2/23

8:13 pm-1:15 pm

1 stop17h 02m

$200

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Fri 2/6

8:47 am-10:49 am

Nonstop2h 02m

Knoxville McGhee Tyson

Mon 2/9

6:00 am-7:46 am

Nonstop1h 46m

$201

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Fri 2/20

8:00 am-7:27 pm

1 stop11h 27m

Knoxville McGhee Tyson

Mon 2/23

8:13 pm-1:15 pm

1 stop17h 02m

$207

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Sat 7/18

1:45 pm-6:17 pm

1 stop4h 32m

Knoxville McGhee Tyson

Mon 7/20

7:20 pm-11:23 pm

1 stop4h 03m

$213

Washington, D.C.Knoxville

DCA - TYS

DCATYS

Washington, D.C. Reagan-National

Thu 2/5

8:47 am-10:49 am

Nonstop2h 02m

Knoxville McGhee Tyson

Mon 2/9

6:00 am-7:46 am

Nonstop1h 46m

$219

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Washington, D.C. Reagan-National Airport and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Washington, D.C. Reagan-National Airport, with most prices found around $201. If you aren’t able to travel during the month of January, then book flights to Knoxville from Washington, D.C. Reagan-National Airport during February instead. Flights to Knoxville in February, while not as cheap as those in January, still average around $264.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Washington, D.C. Reagan-National Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $276. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Washington, D.C. Reagan-National Airport to Knoxville for around $347.

What is the cheapest time of day to depart on your flight to Knoxville?

In the afternoon is the cheapest time of day to fly from Washington, D.C. Reagan-National Airport to Knoxville when you can find flight prices for as low as $233. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $323.

What is the cheapest Washington, D.C. Reagan-National to Knoxville McGhee Tyson flight route?

Fly from Washington, D.C. Reagan-National to Knoxville McGhee Tyson for the best Washington, D.C. Reagan-National - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Washington, D.C. Reagan-National Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $307 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Washington, D.C. Reagan-National Airport for as low as $142 on momondo.

What cabin class options are available on Washington, D.C. Reagan-National to Knoxville McGhee Tyson flights?

There are 3 cabin classes available to choose from on Washington, D.C. Reagan-National to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Washington, D.C. Reagan-National Airport to Knoxville flights?

You could potentially save up to 26% on your flight if you consider stops on a Washington, D.C. Reagan-National Airport to Knoxville flight.

How have Washington, D.C. Reagan-National Airport to Knoxville flight prices changed over time?

As of January 2026, prices for Washington, D.C. Reagan-National Airport to Knoxville flights are approximately 171% more expensive when compared to flights at the same time last year.

When to book flights from Washington, D.C. Reagan-National Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Knoxville (DCA to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Knoxville

Best Price Found

$243

Fastest flight time

1h 49m

Direct flights

Mon, Wed, Thu, Fri, Sat and Sun

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Washington, D.C. Reagan-National Airport in the past 72 hours is $243. The best round-trip flight deal from Washington, D.C. Reagan-National Airport to Knoxville found on momondo in the last 72 hours is $261.
The fastest flight from Washington, D.C. Reagan-National Airport to Knoxville takes 1h 49m
Direct flights go from Washington, D.C. Reagan-National Airport to Knoxville on Monday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is American Airlines.
There is 1 airport in Knoxville. From Washington, D.C. Reagan-National Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Washington, D.C. Reagan-National to Knoxville McGhee Tyson by plane?

    There are 426.9 mi between Washington, D.C. Reagan-National and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 1h 49m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport are updated daily.

  • How many operators does momondo search for flights from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Washington, D.C. Reagan-National Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Washington, D.C. Reagan-National Airport to Knoxville?

  • What is the most popular airline from Washington, D.C. Reagan-National Airport to Knoxville?

Best airlines flying from Washington, D.C. Reagan-National Airport to Knoxville

Compare and see reviews for airlines that fly from Washington, D.C. Reagan-National Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $189Free CancellationRating
7.2
11,169 reviews
Search American Airlines flights

  • American Airlines Flights From Washington, D.C. Reagan-National Airport to Knoxville

    American Airlines flies from Washington, D.C. Reagan-National Airport to Knoxville around 16 times per week, with 11,169 momondo users rating the airline 7.2/10. The cheapest American Airlines deal from Washington, D.C. Reagan-National Airport to Knoxville in the last 72 hours was $189 (round-trip), much lower than the average airfare cost of $311 for American Airlines flights on this route.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Murphy
Alcoa
Crossville
Maryville
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Knoxville?

Finding the right flight to Knoxville from Washington, D.C. is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Washington, D.C. to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Washington, D.C. on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Washington, D.C. to Knoxville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Washington, D.C. to Knoxville.

I’m not ready to book a flight from Washington, D.C. to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Washington, D.C. are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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