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Cheap flights from Washington, D.C. Reagan-National Airport to Florence from $265

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Florence departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Washington, D.C. Reagan-National Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:29 pm - 11:57 pm
DCA
-
FLO
6h 28m
1 stop
American Airlines Logo
6:24 am - 12:44 pm
FLO
-
DCA
6h 20m
1 stop
$531American Airlines
Sun, Sep 27 - Sat, Oct 3
American Airlines Logo
5:50 pm - 11:37 pm
DCA
-
FLO
5h 47m
1 stop
American Airlines Logo
3:22 pm - 8:00 pm
FLO
-
DCA
4h 38m
1 stop
$545American Airlines
Tue, Aug 4 - Sat, Aug 8
American Airlines Logo
5:35 pm - 10:59 pm
DCA
-
FLO
5h 24m
1 stop
American Airlines Logo
6:22 am - 10:58 am
FLO
-
DCA
4h 36m
1 stop
$579American Airlines
Fri, Sep 4 - Mon, Sep 7
American Airlines Logo
8:32 am - 2:56 pm
DCA
-
FLO
6h 24m
1 stop
American Airlines Logo
6:22 am - 12:58 pm
FLO
-
DCA
6h 36m
1 stop
$638American Airlines
Sat, Aug 8 - Fri, Aug 14
American Airlines Logo
7:07 pm - 11:37 pm
DCA
-
FLO
4h 30m
1 stop
American Airlines Logo
2:35 pm - 8:00 pm
FLO
-
DCA
5h 25m
1 stop
$661American Airlines
Fri, Jul 31 - Mon, Aug 3
American Airlines Logo
5:24 pm - 11:37 pm
DCA
-
FLO
6h 13m
2 stops
American Airlines Logo
3:22 pm - 8:00 pm
FLO
-
DCA
4h 38m
1 stop
$672American Airlines
Tue, Aug 4 - Sat, Aug 8
American Airlines Logo
8:32 am - 2:09 pm
DCA
-
FLO
5h 37m
1 stop
American Airlines Logo
5:09 am - 11:12 am
FLO
-
DCA
6h 03m
2 stops
$689American Airlines
Fri, Oct 9 - Wed, Oct 14
American Airlines Logo
8:30 am - 2:10 pm
DCA
-
FLO
5h 40m
1 stop
American Airlines Logo
5:17 am - 12:16 pm
FLO
-
DCA
6h 59m
2 stops
$763American Airlines
Fri, Jul 31 - Sun, Aug 2
American Airlines Logo
6:59 am - 2:10 pm
DCA
-
FLO
7h 11m
2 stops
American Airlines Logo
2:35 pm - 8:41 pm
FLO
-
DCA
6h 06m
2 stops
$865American Airlines
Fri, Jul 31 - Sun, Aug 2
American Airlines Logo
8:32 am - 2:10 pm
DCA
-
FLO
5h 38m
2 stops
American Airlines Logo
1:43 pm - 6:13 pm
FLO
-
DCA
4h 30m
1 stop
$886American Airlines
Sun, Sep 27 - Sat, Oct 3

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American Airlines flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Our best American Airlines deals on Washington, D.C. Reagan-National Airport to Florence, South Carolina flight tickets
American Airlines
Sep 27
DCA5:29 pmWashington, D.C. Reagan-National
6h 28m
1 stop
FLO11:57 pmFlorence
Oct 3
FLO6:24 amFlorence
6h 20m
1 stop
DCA12:44 pmWashington, D.C. Reagan-National
$531
American Airlines
Aug 4
DCA5:50 pmWashington, D.C. Reagan-National
5h 47m
1 stop
FLO11:37 pmFlorence
Aug 8
FLO3:22 pmFlorence
4h 38m
1 stop
DCA8:00 pmWashington, D.C. Reagan-National
$545
American Airlines
Sep 4
DCA5:35 pmWashington, D.C. Reagan-National
5h 24m
1 stop
FLO10:59 pmFlorence
Sep 7
FLO6:22 amFlorence
4h 36m
1 stop
DCA10:58 amWashington, D.C. Reagan-National
$579

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 21, 2026.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sun 9/27

5:29 pm-11:57 pm

1 stop6h 28m

Florence

Sat 10/3

6:24 am-12:44 pm

1 stop6h 20m

$531

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 8/4

5:50 pm-11:37 pm

1 stop5h 47m

Florence

Sat 8/8

3:22 pm-8:00 pm

1 stop4h 38m

$545

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 9/4

5:35 pm-10:59 pm

1 stop5h 24m

Florence

Mon 9/7

6:22 am-10:58 am

1 stop4h 36m

$579

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 8/8

8:32 am-2:56 pm

1 stop6h 24m

Florence

Fri 8/14

6:22 am-12:58 pm

1 stop6h 36m

$638
Quickest round-trip

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 7/31

7:07 pm-11:37 pm

1 stop4h 30m

Florence

Mon 8/3

2:35 pm-8:00 pm

1 stop5h 25m

$661

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 8/4

5:24 pm-11:37 pm

2 stops6h 13m

Florence

Sat 8/8

3:22 pm-8:00 pm

1 stop4h 38m

$672

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 10/9

8:32 am-2:09 pm

1 stop5h 37m

Florence

Wed 10/14

5:09 am-11:12 am

2 stops6h 03m

$689

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 7/31

8:30 am-2:10 pm

1 stop5h 40m

Florence

Sun 8/2

5:17 am-12:16 pm

2 stops6h 59m

$763

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 7/31

6:59 am-2:10 pm

2 stops7h 11m

Florence

Sun 8/2

2:35 pm-8:41 pm

2 stops6h 06m

$865

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sun 9/27

8:32 am-2:10 pm

2 stops5h 38m

Florence

Sat 10/3

1:43 pm-6:13 pm

1 stop4h 30m

$886

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Washington, D.C. Reagan-National to Florence?

American Airlines is the most popular carrier operating from Washington, D.C. Reagan-National to Florence

When to book flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Florence, South Carolina (DCA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Fastest flight time

3h 25m

Direct flights

None
The fastest flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina takes 3h 25m
There are no direct flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina. There are no popular flight routes from Washington, D.C. Reagan-National Airport to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Washington, D.C. Reagan-National Airport to Florence, South Carolina

  • How far is Washington, D.C. Reagan-National to Florence by plane?

    Florence is 355.3 mi away from Washington, D.C. Reagan-National. In terms of flight time, this usually takes a little over 3h 25m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Florence Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Washington, D.C. Reagan-National Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Washington, D.C..

Can I find flights from Washington, D.C. to Florence with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Washington, D.C. to Florence flights to just show those with flexible booking policies.

How can momondo help me find flights from Washington, D.C. to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Washington, D.C..

I’m not ready to book a flight from Washington, D.C. to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Washington, D.C.. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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