Cheap flights from Washington, D.C. Reagan-National Airport to Florence from $209

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Florence departing on 12/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Washington, D.C. Reagan-National Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 10:51 amDCA-FLO
3h 51m1 stop
American Airlines Logo
12:51 pm - 5:34 pmFLO-DCA
4h 43m1 stop
$209American Airlines
Find Deal
Sat, Dec 13 - Wed, Dec 24
American Airlines Logo
1:44 pm - 6:05 pmDCA-FLO
4h 21m1 stop
American Airlines Logo
5:15 am - 9:20 amFLO-DCA
4h 05m1 stop
$439American Airlines
Find Deal
Sat, Dec 27 - Sun, Jan 4
American Airlines Logo
5:24 pm - 12:15 amDCA-FLO
6h 51m1 stop
American Airlines Logo
5:15 am - 11:10 amFLO-DCA
5h 55m2 stops
$479American Airlines
Find Deal
Sat, Dec 13 - Wed, Dec 24
American Airlines Logo
3:00 pm - 11:38 pmDCA-FLO
8h 38m2 stops
American Airlines Logo
2:30 pm - 7:40 amFLO-DCA
17h 10m2 stops
$559American Airlines
Find Deal
Mon, Mar 30 - Fri, Apr 3
American Airlines Logo
5:30 pm - 11:38 pmDCA-FLO
6h 08m1 stop
American Airlines Logo
2:30 pm - 7:40 amFLO-DCA
17h 10m2 stops
$578American Airlines
Find Deal
Mon, Mar 30 - Fri, Apr 3
American Airlines Logo
8:30 am - 12:42 pmDCA-FLO
4h 12m1 stop
American Airlines Logo
5:15 am - 11:17 amFLO-DCA
6h 02m2 stops
$725American Airlines
Find Deal
Sat, Dec 27 - Sun, Jan 4
American Airlines Logo
6:47 am - 10:24 amDCA-FLO
3h 37m1 stop
American Airlines Logo
2:30 pm - 8:35 pmFLO-DCA
6h 05m1 stop
$831American Airlines
Find Deal
Mon, Mar 30 - Fri, Apr 3

American Airlines flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Our best American Airlines deals on Washington, D.C. Reagan-National Airport to Florence, South Carolina flight tickets
American Airlines
Dec 13
DCA7:00 amWashington, D.C. Reagan-National
3h 51m
1 stop
FLO10:51 amFlorence
Dec 24
FLO12:51 pmFlorence
4h 43m
1 stop
DCA5:34 pmWashington, D.C. Reagan-National
American Airlines
Oct 18
DCA5:30 pmWashington, D.C. Reagan-National
6h 33m
1 stop
FLO12:03 amFlorence
Oct 19
FLO5:14 amFlorence
5h 46m
1 stop
DCA11:00 amWashington, D.C. Reagan-National
American Airlines
Oct 18
DCA6:10 amWashington, D.C. Reagan-National
7h 54m
2 stops
FLO2:04 pmFlorence
Oct 19
FLO5:14 amFlorence
4h 10m
1 stop
DCA9:24 amWashington, D.C. Reagan-National

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 9, 2025.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 12/13

7:00 am-10:51 am

1 stop3h 51m

Florence

Wed 12/24

12:51 pm-5:34 pm

1 stop4h 43m

$209

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 12/27

1:44 pm-6:05 pm

1 stop4h 21m

Florence

Sun 1/4

5:15 am-9:20 am

1 stop4h 05m

$439

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 12/13

5:24 pm-12:15 am

1 stop6h 51m

Florence

Wed 12/24

5:15 am-11:10 am

2 stops5h 55m

$479

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 3/30

3:00 pm-11:38 pm

2 stops8h 38m

Florence

Fri 4/3

2:30 pm-7:40 am

2 stops17h 10m

$559

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 3/30

5:30 pm-11:38 pm

1 stop6h 08m

Florence

Fri 4/3

2:30 pm-7:40 am

2 stops17h 10m

$578

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 12/27

8:30 am-12:42 pm

1 stop4h 12m

Florence

Sun 1/4

5:15 am-11:17 am

2 stops6h 02m

$725

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 3/30

6:47 am-10:24 am

1 stop3h 37m

Florence

Fri 4/3

2:30 pm-8:35 pm

1 stop6h 05m

$831

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence, South Carolina?

On average, the least expensive day to fly to Florence, South Carolina from Washington, D.C. Reagan-National Airport is on a Friday. momondo users have found tickets for Friday departures for as low as $288. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Sunday is the most expensive day to depart from Washington, D.C. Reagan-National Airport because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $390.

What is the cheapest time of day to depart on your flight to Florence, South Carolina?

According to our data, the cheapest time of day to fly to Florence, South Carolina is in the morning. momondo users have found flights departing from Washington, D.C. Reagan-National Airport to Florence, South Carolina in the morning for as low as $291. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the evening is when there is more demand to fly to Florence, South Carolina, so prices are often more expensive at around $429 per ticket.

Can stopping save me money on Washington, D.C. Reagan-National Airport to Florence, South Carolina flights?

You could potentially save up to 25% on your flight if you consider stops on a Washington, D.C. Reagan-National Airport to Florence, South Carolina flight.

When to book flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Florence, South Carolina (DCA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Direct flights

None
There are no direct flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina. There are no popular flight routes from Washington, D.C. Reagan-National Airport to Florence, South Carolina.
  • How far is Washington, D.C. Reagan-National to Florence by plane?

    Florence is 355.3 mi away from Washington, D.C. Reagan-National. In terms of flight time, this usually takes a little over 3h 37m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Florence Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Washington, D.C. Reagan-National Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Washington, D.C..

Can I find flights from Washington, D.C. to Florence with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Washington, D.C. to Florence flights to just show those with flexible booking policies.

How can momondo help me find flights from Washington, D.C. to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Washington, D.C..

I’m not ready to book a flight from Washington, D.C. to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Washington, D.C.. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Sat 11/8
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