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Cheap flights from Washington, D.C. Reagan-National Airport to Florence from $476

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Washington, D.C. Reagan-National Airport to Florence departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Washington, D.C. Reagan-National Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:40 am - 10:00 pm
DCA
-
FLO
10h 20m
2 stops
American Airlines Logo
2:35 pm - 6:22 pm
FLO
-
DCA
3h 47m
1 stop
$493American Airlines
Tue, Jun 23 - Wed, Jul 1
American Airlines Logo
11:40 am - 10:00 pm
DCA
-
FLO
10h 20m
2 stops
American Airlines Logo
5:05 am - 2:58 pm
FLO
-
DCA
9h 53m
2 stops
$498American Airlines
Tue, Jun 23 - Tue, Jun 30
American Airlines Logo
5:26 pm - 10:00 pm
DCA
-
FLO
4h 34m
1 stop
American Airlines Logo
2:35 pm - 6:22 pm
FLO
-
DCA
3h 47m
1 stop
$551American Airlines
Tue, Jun 23 - Wed, Jul 1
American Airlines Logo
9:51 am - 3:50 pm
DCA
-
FLO
5h 59m
1 stop
American Airlines Logo
4:02 pm - 10:15 pm
FLO
-
DCA
6h 13m
1 stop
$554American Airlines
Fri, Apr 24 - Tue, May 5
American Airlines Logo
3:20 pm - 10:00 pm
DCA
-
FLO
6h 40m
1 stop
American Airlines Logo
5:05 am - 2:58 pm
FLO
-
DCA
9h 53m
2 stops
$556American Airlines
Sat, Jun 27 - Tue, Jun 30
American Airlines Logo
3:20 pm - 10:00 pm
DCA
-
FLO
6h 40m
1 stop
American Airlines Logo
5:05 am - 9:29 am
FLO
-
DCA
4h 24m
1 stop
$559American Airlines
Fri, May 22 - Sun, May 24
American Airlines Logo
2:30 pm - 9:47 pm
DCA
-
FLO
7h 17m
2 stops
American Airlines Logo
4:16 pm - 10:37 pm
FLO
-
DCA
6h 21m
2 stops
$564American Airlines
Mon, May 11 - Mon, May 18
American Airlines Logo
9:51 am - 3:50 pm
DCA
-
FLO
5h 59m
1 stop
American Airlines Logo
5:20 am - 9:06 am
FLO
-
DCA
3h 46m
1 stop
$569American Airlines
Wed, Apr 29 - Sun, May 3
American Airlines Logo
11:40 am - 10:00 pm
DCA
-
FLO
10h 20m
2 stops
American Airlines Logo
5:05 am - 9:29 am
FLO
-
DCA
4h 24m
1 stop
$575American Airlines
Tue, Jun 23 - Sun, Jun 28
American Airlines Logo
11:40 am - 10:00 pm
DCA
-
FLO
10h 20m
2 stops
American Airlines Logo
5:05 am - 12:19 pm
FLO
-
DCA
7h 14m
2 stops
$580American Airlines
Tue, Jun 23 - Wed, Jul 1

American Airlines flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Our best American Airlines deals on Washington, D.C. Reagan-National Airport to Florence, South Carolina flight tickets
American Airlines
Jun 23
DCA11:40 amWashington, D.C. Reagan-National
10h 20m
2 stops
FLO10:00 pmFlorence
Jun 30
FLO5:05 amFlorence
5h 45m
1 stop
DCA10:50 amWashington, D.C. Reagan-National
$493
American Airlines
Jun 23
DCA11:40 amWashington, D.C. Reagan-National
10h 20m
2 stops
FLO10:00 pmFlorence
Jun 30
FLO5:05 amFlorence
9h 53m
2 stops
DCA2:58 pmWashington, D.C. Reagan-National
$498
American Airlines
Jun 23
DCA5:26 pmWashington, D.C. Reagan-National
4h 34m
1 stop
FLO10:00 pmFlorence
Jul 1
FLO2:35 pmFlorence
3h 47m
1 stop
DCA6:22 pmWashington, D.C. Reagan-National
$551

momondo Fare Finder

 
Customize your flight search to find flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 16, 2026.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 6/23

11:40 am-10:00 pm

2 stops10h 20m

Florence

Wed 7/1

2:35 pm-6:22 pm

1 stop3h 47m

$493

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 6/23

11:40 am-10:00 pm

2 stops10h 20m

Florence

Tue 6/30

5:05 am-2:58 pm

2 stops9h 53m

$498
Quickest round-trip

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 6/23

5:26 pm-10:00 pm

1 stop4h 34m

Florence

Wed 7/1

2:35 pm-6:22 pm

1 stop3h 47m

$551

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 4/24

9:51 am-3:50 pm

1 stop5h 59m

Florence

Tue 5/5

4:02 pm-10:15 pm

1 stop6h 13m

$554

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 6/27

3:20 pm-10:00 pm

1 stop6h 40m

Florence

Tue 6/30

5:05 am-2:58 pm

2 stops9h 53m

$556

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 5/22

3:20 pm-10:00 pm

1 stop6h 40m

Florence

Sun 5/24

5:05 am-9:29 am

1 stop4h 24m

$559

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 5/11

2:30 pm-9:47 pm

2 stops7h 17m

Florence

Mon 5/18

4:16 pm-10:37 pm

2 stops6h 21m

$564

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Wed 4/29

9:51 am-3:50 pm

1 stop5h 59m

Florence

Sun 5/3

5:20 am-9:06 am

1 stop3h 46m

$569

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 6/23

11:40 am-10:00 pm

2 stops10h 20m

Florence

Sun 6/28

5:05 am-9:29 am

1 stop4h 24m

$575

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Tue 6/23

11:40 am-10:00 pm

2 stops10h 20m

Florence

Wed 7/1

5:05 am-12:19 pm

2 stops7h 14m

$580

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Washington, D.C. Reagan-National Airport to Florence, South Carolina flights?

You could potentially save up to 25% on your flight if you consider stops on a Washington, D.C. Reagan-National Airport to Florence, South Carolina flight.

When to book flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Washington, D.C. Reagan-National Airport to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Washington, D.C. Reagan-National Airport to Florence, South Carolina (DCA to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina

Fastest flight time

5h 52m

Direct flights

None
The fastest flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina takes 5h 52m
There are no direct flights from Washington, D.C. Reagan-National Airport to Florence, South Carolina. There are no popular flight routes from Washington, D.C. Reagan-National Airport to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Washington, D.C. Reagan-National Airport to Florence, South Carolina

  • How far is Washington, D.C. Reagan-National to Florence by plane?

    Florence is 355.3 mi away from Washington, D.C. Reagan-National. In terms of flight time, this usually takes a little over 5h 52m.

  • When did momondo last update prices for flights from Washington, D.C. Reagan-National Airport to Florence Airport?

    Prices for flights from Washington, D.C. Reagan-National Airport to Florence Airport are updated daily.

  • How old do you have to be to fly from Washington, D.C. Reagan-National Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Washington, D.C. Reagan-National Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Washington, D.C. to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Washington, D.C..

Can I find flights from Washington, D.C. to Florence with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Washington, D.C. to Florence flights to just show those with flexible booking policies.

How can momondo help me find flights from Washington, D.C. to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Washington, D.C..

I’m not ready to book a flight from Washington, D.C. to Florence right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Florence from Washington, D.C.. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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