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Cheap flights from Prague to St. Louis from $424

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Prague to St. Louis departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Prague to St. Louis

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:30 am - 5:44 pm
PRG
-
STL
17h 14m
2 stops
United Airlines Logo
3:15 pm - 1:55 pm
STL
-
PRG
15h 40m
2 stops
$956United Airlines
Wed, Feb 18 - Sun, Feb 22
United Airlines Logo
7:30 am - 10:59 pm
PRG
-
STL
22h 29m
2 stops
United Airlines Logo
3:15 pm - 1:55 pm
STL
-
PRG
15h 40m
2 stops
$957United Airlines
Wed, Feb 18 - Sun, Feb 22
Lufthansa Logo
7:30 am - 8:23 pm
PRG
-
STL
19h 53m
2 stops
Lufthansa Logo
3:30 pm - 1:40 pm
STL
-
PRG
15h 10m
1 stop
$961Lufthansa
Wed, Feb 18 - Fri, Aug 21
United Airlines Logo
7:35 am - 9:05 pm
PRG
-
STL
20h 30m
2 stops
United Airlines Logo
3:30 pm - 5:55 pm
STL
-
PRG
19h 25m
1 stop
$966United Airlines
Mon, Feb 16 - Sun, Aug 23
Air Canada Logo
7:25 am - 3:29 pm
PRG
-
STL
39h 04m
2 stops
Air Canada Logo
12:10 pm - 5:45 pm
STL
-
PRG
22h 35m
2 stops
$968Air Canada
Tue, Feb 17 - Thu, Aug 20
United Airlines Logo
10:25 am - 10:59 pm
PRG
-
STL
19h 34m
2 stops
United Airlines Logo
1:27 pm - 12:45 pm
STL
-
PRG
16h 18m
2 stops
$970United Airlines
Mon, Feb 16 - Fri, Aug 21
Air Canada Logo
7:30 am - 5:44 pm
PRG
-
STL
17h 14m
3 stops
Air Canada Logo
4:05 pm - 2:15 pm
STL
-
PRG
15h 10m
2 stops
$1,233Air Canada
Wed, Feb 18 - Sun, Feb 22
Air Canada Logo
7:30 am - 5:44 pm
PRG
-
STL
17h 14m
3 stops
Air Canada Logo
4:05 pm - 2:15 pm
STL
-
PRG
15h 10m
2 stops
$1,317Air Canada
Wed, Feb 18 - Sun, Feb 22
Air Canada Logo
10:00 am - 10:59 pm
PRG
-
STL
19h 59m
3 stops
Air Canada Logo
2:40 pm - 11:00 am
STL
-
PRG
13h 20m
2 stops
$2,497Air Canada
Wed, Feb 18 - Fri, Aug 21
Multiple Airlines Logo
7:30 am - 7:14 pm
PRG
-
STL
18h 44m
3 stops
Multiple Airlines Logo
6:55 pm - 8:30 pm
STL
-
PRG
18h 35m
3 stops
$2,629Multiple Airlines
Wed, Feb 18 - Sun, Feb 22

United Airlines flights from Prague to St. Louis

Our best United Airlines deals on Prague to St. Louis flight tickets
United Airlines
Feb 18
PRG7:30 amVáclav Havel Prague
17h 14m
2 stops
STL5:44 pmLambert-St Louis
Feb 22
STL3:15 pmLambert-St Louis
15h 40m
2 stops
PRG1:55 pmVáclav Havel Prague
$956
United Airlines
Feb 18
PRG7:30 amVáclav Havel Prague
22h 29m
2 stops
STL10:59 pmLambert-St Louis
Feb 22
STL3:15 pmLambert-St Louis
15h 40m
2 stops
PRG1:55 pmVáclav Havel Prague
$957
United Airlines
Feb 11
PRG7:30 amVáclav Havel Prague
18h 57m
2 stops
STL7:27 pmLambert-St Louis
Aug 19
STL9:23 amLambert-St Louis
20h 22m
2 stops
PRG12:45 pmVáclav Havel Prague
$960

Air Canada flights from Prague to St. Louis

Our best Air Canada deals on Prague to St. Louis flight tickets
Air Canada
Feb 17
PRG7:25 amVáclav Havel Prague
39h 04m
2 stops
STL3:29 pmLambert-St Louis
Aug 20
STL12:10 pmLambert-St Louis
22h 35m
2 stops
PRG5:45 pmVáclav Havel Prague
$968
Air Canada
Feb 18
PRG7:30 amVáclav Havel Prague
17h 14m
3 stops
STL5:44 pmLambert-St Louis
Feb 22
STL4:05 pmLambert-St Louis
15h 10m
2 stops
PRG2:15 pmVáclav Havel Prague
$1,233
Air Canada
Feb 18
PRG7:30 amVáclav Havel Prague
17h 14m
3 stops
STL5:44 pmLambert-St Louis
Feb 22
STL4:05 pmLambert-St Louis
15h 10m
2 stops
PRG2:15 pmVáclav Havel Prague
$1,317

momondo Fare Finder

 
Customize your flight search to find flights from Prague to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Prague to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

7:30 am-5:44 pm

2 stops17h 14m

Lambert-St Louis

Sun 2/22

3:15 pm-1:55 pm

2 stops15h 40m

$956

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

7:30 am-10:59 pm

2 stops22h 29m

Lambert-St Louis

Sun 2/22

3:15 pm-1:55 pm

2 stops15h 40m

$957

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

7:30 am-8:23 pm

2 stops19h 53m

Lambert-St Louis

Fri 8/21

3:30 pm-1:40 pm

1 stop15h 10m

$961

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Mon 2/16

7:35 am-9:05 pm

2 stops20h 30m

Lambert-St Louis

Sun 8/23

3:30 pm-5:55 pm

1 stop19h 25m

$966

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Tue 2/17

7:25 am-3:29 pm

2 stops39h 04m

Lambert-St Louis

Thu 8/20

12:10 pm-5:45 pm

2 stops22h 35m

$968

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Mon 2/16

10:25 am-10:59 pm

2 stops19h 34m

Lambert-St Louis

Fri 8/21

1:27 pm-12:45 pm

2 stops16h 18m

$970

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

7:30 am-5:44 pm

3 stops17h 14m

Lambert-St Louis

Sun 2/22

4:05 pm-2:15 pm

2 stops15h 10m

$1,233

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

7:30 am-5:44 pm

3 stops17h 14m

Lambert-St Louis

Sun 2/22

4:05 pm-2:15 pm

2 stops15h 10m

$1,317

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

10:00 am-10:59 pm

3 stops19h 59m

Lambert-St Louis

Fri 8/21

2:40 pm-11:00 am

2 stops13h 20m

$2,497

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 2/18

7:30 am-7:14 pm

3 stops18h 44m

Lambert-St Louis

Sun 2/22

6:55 pm-8:30 pm

3 stops18h 35m

$2,629

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to St. Louis from

How to get the cheapest flight ticket from Prague to St. Louis

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Prague to St. Louis flights?

You could potentially save up to 20% on your flight if you consider stops on a Prague to St. Louis flight.

When to book flights from Prague to St. Louis

Are you open to changing your travel dates? Check out the ideal times to fly from Prague to St. Louis according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Prague to St. Louis (PRG to STL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Prague to St. Louis

Fastest flight time

32h 47m

Direct flights

None
The fastest flight from Prague to St. Louis takes 32h 47m
There are no direct flights from Prague to St. Louis. There are no popular flight routes from Prague to St. Louis.
Search flight deals

  • How far is Václav Havel Prague to Lambert-St Louis by plane?

    There are 4789.6 mi between Václav Havel Prague and Lambert-St Louis. By plane, this route typically takes 32h 47m.

  • When did momondo last update prices for flights from Václav Havel Prague Airport to Lambert-St Louis Airport?

    Prices for flights from Václav Havel Prague Airport to Lambert-St Louis Airport refresh daily.

  • How old do you have to be to fly from Václav Havel Prague Airport to Lambert-St Louis Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Václav Havel Prague Airport to Lambert-St Louis Airport.

  • What documentation or ID do you need to fly to Lambert-St Louis Airport?

    The travel and health documents required for your trip to Lambert-St Louis Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Lambert-St Louis Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
St. Charles
Chesterfield
Hermann
Fairview Heights
Maryland Heights
Florissant
O'Fallon
Collinsville
St. Peters
Fenton
Wentzville
Alton
Farmington
Clayton
Edwardsville
Eureka
Festus
Litchfield
Glencoe
Shrewsbury

Why use momondo?

Why should I use momondo to find a flight deal from Prague to St. Louis?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Prague to St. Louis. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Prague to St. Louis with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Prague to St. Louis flights to just show those with flexible booking policies.

How can momondo help me find flights from Prague to St. Louis?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to St. Louis from Prague.

I’m not ready to book a flight from Prague to St. Louis right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Prague to St. Louis flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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