How many flights depart from Portland, Maine to South Carolina on average per week?

9 flights are operational weekly from Portland, Maine to South Carolina as of November 2026. The most popular departure day for this route is Thu, with 33% of flights per week taking off on this day.

What is the cheapest airline that flies from Portland to South Carolina?

Breeze Airways, Delta, and United Airlines are the most popular carriers operating from Portland to South Carolina

How many flights depart from Portland, Maine to South Carolina on average per day?

As of November 2026, there are 1 flights per day flying from Portland, Maine to South Carolina. The most common time of day flights depart is 5:00PM, with 66% of flights taking off in the afternoon.

What airlines fly to South Carolina?

American Airlines, Breeze Airways and JetBlue are the top three most popular airlines that fly to South Carolina from Portland, Maine according to our data. American Airlines is the first choice among our users, with 30% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 7 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Portland Airport to South Carolina?

Prices for flights from Portland Airport to South Carolina are updated daily.

How many operators does momondo search for flights from Portland Airport to South Carolina?

There are 5 operators available for flights from Portland Airport to South Carolina as of November 2026.

How old do you have to be to fly from Portland Airport to South Carolina?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to South Carolina.

What documentation or ID do you need to fly to South Carolina?

The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$79 Cheap Flights from Portland, Maine to South Carolina in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Portland, Maine to South Carolina

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:00 pm - 7:43 pmPWM Portland-CHS Charleston

2h 43mnonstop

1:55 pm - 4:20 pmCHS Charleston-PWM Portland

2h 25mnonstop

$128Breeze Airways

Fri, Jan 22 - Mon, Jan 25

5:00 pm - 7:43 pmPWM Portland-CHS Charleston

2h 43mnonstop

1:55 pm - 4:20 pmCHS Charleston-PWM Portland

2h 25mnonstop

$128Breeze Airways

Mon, Jan 11 - Fri, Jan 22

5:00 pm - 7:43 pmPWM Portland-CHS Charleston

2h 43mnonstop

8:23 pm - 9:08 amCHS Charleston-PWM Portland

36h 45m3 stops Tampa Atlanta Hartsfield-Jackson Orlando

$240Multiple Airlines

Fri, Jan 22 - Mon, Jan 25

5:00 pm - 7:43 pmPWM Portland-CHS Charleston

2h 43mnonstop

4:57 pm - 11:48 amCHS Charleston-PWM Portland

42h 51m2 stops Fort Lauderdale Raleigh-Durham

$253Multiple Airlines

Fri, Jan 15 - Mon, Jan 18

7:00 am - 11:49 amPWM Portland-CHS Charleston

4h 49m1 stop Charlotte Douglas

5:30 pm - 10:02 pmCHS Charleston-PWM Portland

4h 32m1 stop Charlotte Douglas

$345American Airlines

Tue, Feb 9 - Tue, Feb 16

4:50 pm - 10:04 pmPWM Portland-CHS Charleston

5h 14m1 stop Detroit Metropolitan Wayne County

4:30 pm - 11:23 pmCHS Charleston-PWM Portland

6h 53m1 stop Atlanta Hartsfield-Jackson

$345Delta

Sat, May 8 - Sat, May 15

6:00 am - 11:26 amPWM Portland-CHS Charleston

5h 26m1 stop Atlanta Hartsfield-Jackson

7:30 am - 12:13 pmCHS Charleston-PWM Portland

4h 43m1 stop Atlanta Hartsfield-Jackson

$345Delta

Wed, May 5 - Sat, May 15

9:12 am - 2:20 pmPWM Portland-CHS Charleston

5h 08m1 stop Newark

7:56 pm - 11:58 pmCHS Charleston-PWM Portland

4h 02m1 stop Washington, D.C. Dulles Intl

$345United Airlines

Wed, Dec 16 - Wed, Dec 16

5:36 am - 12:16 pmPWM Portland-CAE Columbia Metropolitan

6h 40m1 stop Charlotte Douglas

6:40 pm - 11:31 pmCAE Columbia Metropolitan-PWM Portland

4h 51m1 stop Washington, D.C. Reagan-National

$349American Airlines

Thu, Dec 3 - Sun, Dec 6

7:00 am - 3:32 pmPWM Portland-CHS Charleston

8h 32m2 stops Newark Washington, D.C. Dulles Intl

7:56 pm - 11:58 pmCHS Charleston-PWM Portland

4h 02m1 stop Washington, D.C. Dulles Intl

$350United Airlines

Wed, Dec 16 - Wed, Dec 16

Cheap last minute flights

Enter your travel dates to find the best prices.

5:18 pm - 9:43 pmPWM Portland-CAE Columbia Metropolitan

4h 25m1 stop New York LaGuardia

5:00 pm - 11:20 pmCAE Columbia Metropolitan-PWM Portland

6h 20m1 stop New York LaGuardia

$394Delta

Wed, Nov 18 - Wed, Dec 2

12:45 pm - 11:53 pmPWM Portland-CAE Columbia Metropolitan

11h 08m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

3:46 pm - 11:33 pmCAE Columbia Metropolitan-PWM Portland

7h 47m1 stop Atlanta Hartsfield-Jackson

$399Delta

Wed, Nov 18 - Wed, Dec 2

5:50 am - 2:17 pmPWM Portland-CAE Columbia Metropolitan

8h 27m2 stops Newark Washington, D.C. Dulles Intl

10:00 am - 7:25 pmCAE Columbia Metropolitan-PWM Portland

9h 25m2 stops Washington, D.C. Dulles Intl Newark

$404United Airlines

Wed, Nov 18 - Wed, Dec 2

5:30 am - 9:59 amPWM Portland-CAE Columbia Metropolitan

4h 29m1 stop Washington, D.C. Dulles Intl

7:54 pm - 11:59 pmCAE Columbia Metropolitan-PWM Portland

4h 05m1 stop Washington, D.C. Dulles Intl

$464United Airlines

Sat, Nov 14 - Mon, Nov 16

6:47 pm - 11:18 pmPWM Portland-CHS Charleston

4h 31m1 stop Philadelphia

10:19 am - 2:21 pmCHS Charleston-PWM Portland

4h 02m1 stop Washington, D.C. Reagan-National

$529American Airlines

Wed, Nov 18 - Sat, Nov 21

12:13 pm - 9:04 pmPWM Portland-CHS Charleston

8h 51m2 stops Washington, D.C. Reagan-National Charlotte Douglas

5:26 pm - 11:55 pmCHS Charleston-PWM Portland

6h 29m1 stop Charlotte Douglas

$534American Airlines

Wed, Nov 18 - Sat, Nov 21

5:09 pm - 9:32 amPWM Portland-GSP Greenville

16h 23m2 stops Raleigh-Durham Tampa

8:32 pm - 9:08 amGSP Greenville-PWM Portland

12h 36m1 stop Orlando

$534Breeze Airways

Wed, Nov 18 - Fri, Nov 20

6:31 pm - 7:54 amPWM Portland-GSP Greenville

13h 23m2 stops Tampa Fort Lauderdale

10:42 am - 2:25 pmGSP Greenville-PWM Portland

3h 43m1 stop Pittsburgh

$552Multiple Airlines

Wed, Nov 18 - Thu, Nov 19

10:01 am - 8:04 amPWM Portland-CHS Charleston

22h 03m1 stop Fort Myers SW Florida Intl

2:13 pm - 9:08 amCHS Charleston-PWM Portland

18h 55m1 stop Orlando

$573Breeze Airways

Thu, Nov 19 - Thu, Nov 26

9:48 am - 8:28 amPWM Portland-GSP Greenville

22h 40m1 stop Orlando

8:52 pm - 4:24 pmGSP Greenville-PWM Portland

19h 32m2 stops Tampa Raleigh-Durham

$624Multiple Airlines

Sat, Nov 14 - Mon, Nov 16

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Breeze Airways flights from Portland, Maine to South Carolina

Our best Breeze Airways deals on Portland, Maine to South Carolina flight tickets

Breeze Airways

Jan 22

PWM5:00 pmPortland

2h 43m

CHS7:43 pmCharleston

Jan 25

CHS1:55 pmCharleston

2h 25m

PWM4:20 pmPortland

$128

Breeze Airways

Dec 7

PWM5:35 pmPortland

2h 43m

CHS8:18 pmCharleston

Dec 11

CHS2:30 pmCharleston

2h 25m

PWM4:55 pmPortland

$143

Breeze Airways

Dec 7

PWM5:35 pmPortland

2h 43m

CHS8:18 pmCharleston

Dec 11

CHS2:30 pmCharleston

2h 25m

PWM4:55 pmPortland

$152

American Airlines flights from Portland, Maine to South Carolina

Our best American Airlines deals on Portland, Maine to South Carolina flight tickets

American Airlines

Dec 3

PWM5:36 amPortland

6h 40m

1 stop

CAE12:16 pmColumbia Metropolitan

Dec 6

CAE6:40 pmColumbia Metropolitan

4h 51m

1 stop

PWM11:31 pmPortland

$349

American Airlines

Jan 25

PWM6:00 amPortland

4h 45m

1 stop

MYR10:45 amMyrtle Beach Intl

Feb 2

MYR5:12 pmMyrtle Beach Intl

4h 22m

1 stop

PWM9:34 pmPortland

$377

American Airlines

Feb 27

PWM8:03 amPortland

5h 53m

1 stop

MYR1:56 pmMyrtle Beach Intl

Mar 7

MYR6:25 pmMyrtle Beach Intl

4h 31m

1 stop

PWM10:56 pmPortland

$393

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Fri 1/22

5:00 pm-7:43 pm

Nonstop2h 43m

Charleston

Mon 1/25

1:55 pm-4:20 pm

Nonstop2h 25m

$128

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Mon 1/11

5:00 pm-7:43 pm

Nonstop2h 43m

Charleston

Fri 1/22

1:55 pm-4:20 pm

Nonstop2h 25m

$128

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Fri 1/22

5:00 pm-7:43 pm

Nonstop2h 43m

Charleston

Mon 1/25

8:23 pm-9:08 am

3 stops36h 45m

$240

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Fri 1/15

5:00 pm-7:43 pm

Nonstop2h 43m

Charleston

Mon 1/18

4:57 pm-11:48 am

2 stops42h 51m

$253

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Tue 2/9

7:00 am-11:49 am

1 stop4h 49m

Charleston

Tue 2/16

5:30 pm-10:02 pm

1 stop4h 32m

$345

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Sat 5/8

4:50 pm-10:04 pm

1 stop5h 14m

Charleston

Sat 5/15

4:30 pm-11:23 pm

1 stop6h 53m

$345

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Wed 5/5

6:00 am-11:26 am

1 stop5h 26m

Charleston

Sat 5/15

7:30 am-12:13 pm

1 stop4h 43m

$345

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Wed 12/16

9:12 am-2:20 pm

1 stop5h 08m

Charleston

Wed 12/16

7:56 pm-11:58 pm

1 stop4h 02m

$345

PortlandColumbia

PWM Portland - CAE Columbia Metropolitan

PWMCAE

Portland

Thu 12/3

5:36 am-12:16 pm

1 stop6h 40m

Columbia Metropolitan

Sun 12/6

6:40 pm-11:31 pm

1 stop4h 51m

$349

PortlandCharleston

PWM Portland - CHS Charleston

PWMCHS

Portland

Wed 12/16

7:00 am-3:32 pm

2 stops8h 32m

Charleston

Wed 12/16

7:56 pm-11:58 pm

1 stop4h 02m

$350

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Portland, Maine is in January. Flight prices, which tend to average around $266, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to South Carolina from Portland, Maine during August instead. Flights to South Carolina in August, while not as cheap as those in January, still average around $329.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $169. The most expensive day to fly to South Carolina is Wednesday, with ticket prices averaging around $333.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Portland, Maine to South Carolina flights are usually those with departure times in the morning. Our users have found flights to South Carolina in the morning for as low as $169. Try not to purchase tickets in the afternoon because they tend to be around $261. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Portland to South Carolina flight route?

Fly from Portland to Charleston for the best Portland - South Carolina flight prices

How far in advance should I book a flight from Portland, Maine to South Carolina?

You are more likely to see cheaper flights to South Carolina from Portland, Maine when booking weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $338 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Portland, Maine for as low as $126 on momondo.

What cabin class options are available on Portland, Maine to South Carolina flights?

There are 2 cabin classes available to choose from on Portland, Maine to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Portland, Maine to South Carolina flights?

No. A direct flight is the cheapest option for a flight between Portland, Maine to South Carolina.

Cheap Portland, Maine to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to South Carolina

Best Price Found	$79
Fastest flight time	2h 36m
Direct flights	Tue and Sat
Airports in South Carolina	57 airports

The best one-way flight to South Carolina from Portland, Maine in the past 72 hours is $79. The best round-trip flight deal from Portland, Maine to South Carolina found on momondo in the last 72 hours is $128.

The fastest flight from Portland, Maine to South Carolina takes 2h 36m

Direct flights go from Portland, Maine to South Carolina on Tuesday and Saturday. The only airline offering direct flights is Breeze Airways.

There are 57 airports in South Carolina. From Portland, Maine there are direct flights to Charleston (CHS).

Search flight deals

Frequently asked questions about flying from Portland, Maine to South Carolina

When did momondo last update prices for flights from Portland Airport to South Carolina?
Prices for flights from Portland Airport to South Carolina are updated daily.
How many operators does momondo search for flights from Portland Airport to South Carolina?
There are 5 operators available for flights from Portland Airport to South Carolina as of November 2026.
How old do you have to be to fly from Portland Airport to South Carolina?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Portland, Maine to South Carolina?
Based on momondo bookings for flights between Portland, Maine and South Carolina, the leading plane model is Airbus A220-300, making up 83.02% of the total bookings. Other popular models include Boeing 737 MAX 8 with 5.66%, Airbus A321-100/200 with 5.66%, and Embraer 175 with 1.89%.

Best airlines flying from Portland, Maine to South Carolina

Compare and see reviews for airlines that fly from Portland, Maine to South Carolina with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $123	Free Cancellation	Rating 8.2 323 reviews	Search Breeze Airways flights
Delta	PriceFrom $138	Free Cancellation	Rating 7.8 8,721 reviews	Search Delta flights
United Airlines	PriceFrom $198	Free Cancellation	Rating 7.3 10,487 reviews	Search United Airlines flights
Southwest	PriceFrom $229	Free Cancellation	Rating 8.0 4,220 reviews	Search Southwest flights
American Airlines	PriceFrom $234	Free Cancellation	Rating 7.0 12,234 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to South Carolina?

It is quick and easy to find Portland to South Carolina flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to South Carolina that suits you.

Can I find flights from Portland to South Carolina with flexible booking policies on momondo?

Flights from Portland to South Carolina with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Portland to South Carolina?

Once all potential Portland to South Carolina flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Portland and alert you when they change.

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sun 12/13

Sun 12/20

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South Carolina

Popular cities

Other flights from Portland, Maine

Other flights to South Carolina

Airlines

Complete your trip

Feeling lucky

Popular cities in South Carolina

Flights to New Yorkfrom $68

Flights to Los Angelesfrom $38

Flights to Orlandofrom $43

Flights to Miamifrom $47

Flights to San Franciscofrom $38

Flights to Chicagofrom $90

Flights to Las Vegasfrom $38

Flights to Washington, D.C.from $46

Flights to Fort Lauderdalefrom $38

Flights to Bostonfrom $98

Flights to Atlantafrom $46

Flights to Dallasfrom $48

Cheap flights from Portland, Maine to South Carolina from $79

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to South Carolina departing on 3/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Portland, Maine to South Carolina

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Breeze Airways flights from Portland, Maine to South Carolina

Our best Breeze Airways deals on Portland, Maine to South Carolina flight tickets

American Airlines flights from Portland, Maine to South Carolina

Our best American Airlines deals on Portland, Maine to South Carolina flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to South Carolina that are best for you.

See travel insights to South Carolina from

How to get the cheapest flight ticket from Portland, Maine to South Carolina

What is the cheapest month to fly to South Carolina?

What is the cheapest day to depart on your flight to South Carolina?

What is the cheapest time of day to depart on your flight to South Carolina?

What is the cheapest Portland to South Carolina flight route?

How far in advance should I book a flight from Portland, Maine to South Carolina?

What cabin class options are available on Portland, Maine to South Carolina flights?

Can stopping save me money on Portland, Maine to South Carolina flights?

What is the cheapest airline that flies from Portland to South Carolina?

What airlines fly to South Carolina?

How many flights depart from Portland, Maine to South Carolina on average per day?

How many flights depart from Portland, Maine to South Carolina on average per week?

Cheap Portland, Maine to South Carolina flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in South Carolina

Frequently asked questions about flying from Portland, Maine to South Carolina

Best airlines flying from Portland, Maine to South Carolina

Compare and see reviews for airlines that fly from Portland, Maine to South Carolina with momondo

Why use momondo?

An easier way to manage your South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South Carolina

Popular cities in South Carolina

Popular flights according to clicks in the last 7 days on momondo

Portland, Maine flight routes

According to popular flight searches on momondo this year

South Carolina flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to South Carolina

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Complete your trip to South Carolina

Explore popular destinations other users love

According to popular flight searches on momondo this year