Cheap flights from Panama City to Cancún from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cancún departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Avianca Logo
9:45 am - 5:25 pmPTY-CUN
7h 40m1 stop
Avianca Logo
6:25 pm - 8:50 amCUN-PTY
14h 25m1 stop
$305Avianca
Find Deal
Sun, Nov 2 - Sat, Nov 8
Avianca Logo
3:20 am - 5:20 pmPTY-CUN
14h 00m1 stop
Avianca Logo
3:45 pm - 12:45 amCUN-PTY
9h 00m1 stop
$314Avianca
Find Deal
Thu, Sep 18 - Mon, Sep 22
Avianca Logo
3:25 am - 2:40 pmPTY-CUN
11h 15m1 stop
Avianca Logo
3:45 pm - 12:45 amCUN-PTY
9h 00m1 stop
$315Avianca
Find Deal
Fri, Sep 19 - Mon, Sep 22
Avianca Logo
10:05 pm - 5:20 pmPTY-CUN
19h 15m1 stop
Avianca Logo
12:45 pm - 9:10 pmCUN-PTY
8h 25m1 stop
$320Avianca
Find Deal
Mon, Oct 6 - Thu, Oct 16
Copa Airlines Logo
7:11 pm - 9:58 pmPTY-CUN
2h 47mnonstop
Copa Airlines Logo
7:00 am - 9:41 amCUN-PTY
2h 41mnonstop
$322Copa Airlines
Find Deal
Fri, Oct 3 - Thu, Oct 9
Aeromexico Logo
2:39 pm - 11:40 pmPTY-CUN
9h 01m1 stop
Aeromexico Logo
6:15 am - 1:32 pmCUN-PTY
7h 17m1 stop
$324Aeromexico
Find Deal
Fri, Oct 17 - Sun, Dec 7
Copa Airlines Logo
7:11 pm - 9:58 pmPTY-CUN
2h 47mnonstop
Copa Airlines Logo
11:19 am - 2:01 pmCUN-PTY
2h 42mnonstop
$333Copa Airlines
Find Deal
Sat, Oct 18 - Sat, Dec 6
 Logo
2:55 am - 3:50 pmPTY-CUN
12h 55m1 stop
 Logo
11:22 am - 1:00 amCUN-PTY
13h 38m2 stops
Sat, Nov 1 - Sat, Nov 8
 Logo
2:55 am - 3:50 pmPTY-CUN
12h 55m1 stop
 Logo
11:22 am - 1:00 amCUN-PTY
13h 38m2 stops
Sat, Nov 1 - Sat, Nov 8
Aeromexico Logo
2:42 pm - 8:45 pmPTY-CUN
30h 03m1 stop
Aeromexico Logo
9:11 am - 1:42 pmCUN-PTY
28h 31m1 stop
$404Aeromexico
Find Deal
Sun, Oct 5 - Sun, Oct 12

Avianca flights from Panama City to Cancún

Our best Avianca deals on Panama City to Cancún flight tickets
Avianca
Nov 2
PTY9:45 amPanama City Tocumen Intl
7h 40m
1 stop
CUN5:25 pmCancun
Nov 8
CUN6:25 pmCancun
14h 25m
1 stop
PTY8:50 amPanama City Tocumen Intl
Avianca
Sep 18
PTY3:20 amPanama City Tocumen Intl
14h 00m
1 stop
CUN5:20 pmCancun
Sep 22
CUN3:45 pmCancun
9h 00m
1 stop
PTY12:45 amPanama City Tocumen Intl
Avianca
Sep 19
PTY3:25 amPanama City Tocumen Intl
11h 15m
1 stop
CUN2:40 pmCancun
Sep 22
CUN3:45 pmCancun
9h 00m
1 stop
PTY12:45 amPanama City Tocumen Intl

Aeromexico flights from Panama City to Cancún

Our best Aeromexico deals on Panama City to Cancún flight tickets
Aeromexico
Oct 17
PTY2:39 pmPanama City Tocumen Intl
9h 01m
1 stop
CUN11:40 pmCancun
Dec 7
CUN6:15 amCancun
7h 17m
1 stop
PTY1:32 pmPanama City Tocumen Intl
Aeromexico
Oct 5
PTY2:42 pmPanama City Tocumen Intl
30h 03m
1 stop
CUN8:45 pmCancun
Oct 12
CUN9:11 amCancun
28h 31m
1 stop
PTY1:42 pmPanama City Tocumen Intl

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cancún that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama City to Cancún that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Sun 11/2

9:45 am-5:25 pm

1 stop7h 40m

Cancun

Sat 11/8

6:25 pm-8:50 am

1 stop14h 25m

$305

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Thu 9/18

3:20 am-5:20 pm

1 stop14h 00m

Cancun

Mon 9/22

3:45 pm-12:45 am

1 stop9h 00m

$314

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Fri 9/19

3:25 am-2:40 pm

1 stop11h 15m

Cancun

Mon 9/22

3:45 pm-12:45 am

1 stop9h 00m

$315

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Mon 10/6

10:05 pm-5:20 pm

1 stop19h 15m

Cancun

Thu 10/16

12:45 pm-9:10 pm

1 stop8h 25m

$320

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Fri 10/3

7:11 pm-9:58 pm

Nonstop2h 47m

Cancun

Thu 10/9

7:00 am-9:41 am

Nonstop2h 41m

$322

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Fri 10/17

2:39 pm-11:40 pm

1 stop9h 01m

Cancun

Sun 12/7

6:15 am-1:32 pm

1 stop7h 17m

$324

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Sat 10/18

7:11 pm-9:58 pm

Nonstop2h 47m

Cancun

Sat 12/6

11:19 am-2:01 pm

Nonstop2h 42m

$333

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Sat 11/1

2:55 am-3:50 pm

1 stop12h 55m

Cancun

Sat 11/8

11:22 am-1:00 am

2 stops13h 38m

$388

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Sat 11/1

2:55 am-3:50 pm

1 stop12h 55m

Cancun

Sat 11/8

11:22 am-1:00 am

2 stops13h 38m

$390

Panama CityCancún

PTY - CUN

PTYCUN

Panama City Tocumen Intl

Sun 10/5

2:42 pm-8:45 pm

1 stop30h 03m

Cancun

Sun 10/12

9:11 am-1:42 pm

1 stop28h 31m

$404

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cancún from

How to get the cheapest flight ticket from Panama City to Cancún

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Cancún?

What is the cheapest month to fly to Cancún?

If you don’t want to visit Cancún in May, then you should wait until March to fly from Panama City, when ticket prices are also cheap, with an average price of $317.

What is the cheapest day to depart on your flight to Cancún?

The cheapest day to depart from Panama City to Cancún is on a Tuesday when prices can be found for as low as $317. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $330. These prices are subject to change though, so be sure to set up a Price Alert for flights to Cancún.

What is the cheapest time of day to depart on your flight to Cancún?

Our most recent data shows that the best time of day to fly to Cancún is in the afternoon. Flights from Panama City to Cancún during this time can be as low as $298. Flights to Cancún are more costly in the morning, with an average ticket price of $331. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Panama City Tocumen Intl to Cancun flight route?

Fly from Panama City Tocumen Intl to Cancun for the best Panama City Tocumen Intl - Cancun flight prices

How far in advance should I book a flight to Cancún?

You are more likely to see cheaper flights to Cancún from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cancún for around $320 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cancún from Panama City for as low as $295 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Cancun flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Cancun flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Cancún flight prices changed over time?

As of September 2025, prices for Panama City to Cancún flights are approximately 46% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Cancún

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cancún according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cancún (PTY to CUN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cancún

Best Price Found

$405

Fastest flight time

2h 47m

Direct flights

Every day

Airports in Cancún

1 airport
The best one-way flight to Cancún from Panama City in the past 72 hours is $405. The best round-trip flight deal from Panama City to Cancún found on momondo in the last 72 hours is $322.
The fastest flight from Panama City to Cancún takes 2h 47m
Direct flights go from Panama City to Cancún every day.
There is 1 airport near Cancún: Cancun (CUN)
  • How far is Panama City Tocumen Intl to Cancun by plane?

    A flight from Panama City Tocumen Intl to Cancun will travel around 970.7 mi. Flights usually cover this in 2h 47m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cancun Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cancun Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cancun Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cancun Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cancun Airport.

  • What documentation or ID do you need to fly to Cancun Airport?

    The required travel and health documents for your Cancun Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cancun Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama City to Cancún?

  • What is the most popular airline from Panama City to Cancún?

Best airlines flying from Panama City to Cancún

Compare and see reviews for airlines that fly from Panama City to Cancún with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $256Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
AviancaPriceFrom $271Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
AeromexicoPriceFrom $300Free CancellationRating
7.4
1,697 reviews
Search Aeromexico flights
  • Copa Airlines Flights From Panama City to Cancún

    Copa Airlines flight deals from Panama City to Cancún start from $256 round-trip. Over the 32 Copa Airlines flights for this route in a normal week, average airfare is usually $321 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Cancún?

Book flights to Cancún if you plan to visit one of these locations
Playa del Carmen
Isla Mujeres
Holbox
Puerto Morelos
Akumal
Puerto Aventuras
Valladolid
Punta Sam

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cancún?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Cancún from Panama City.

Can I find flights from Panama City to Cancún with flexible booking policies on momondo?

All flight searches from Panama City to Cancún on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cancún?

momondo helps you find the best flight between Panama City and Cancún by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cancún right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cancún flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Wed 10/15
Wed 10/22

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