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Cheap flights from Panama City to Cusco from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$400Avianca
Sun, Feb 1 - Sat, Mar 7
Avianca Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$410Avianca
Tue, Feb 3 - Tue, Feb 10
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$451Avianca
Sat, Jan 31 - Sat, Mar 7
Multiple Airlines Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m1 stop
Multiple Airlines Logo
9:45 pm - 8:50 am
CUZ
-
PTY
11h 05m2 stops
$462Multiple Airlines
Tue, Feb 3 - Tue, Feb 10
Multiple Airlines Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m1 stop
Multiple Airlines Logo
9:37 pm - 8:50 am
CUZ
-
PTY
11h 13m2 stops
$497Multiple Airlines
Wed, Mar 4 - Sat, Mar 7
Multiple Airlines Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Multiple Airlines Logo
9:27 pm - 8:50 am
CUZ
-
PTY
11h 23m2 stops
$499Multiple Airlines
Sat, Feb 28 - Wed, Mar 4
Multiple Airlines Logo
9:45 am - 9:15 pm
PTY
-
CUZ
11h 30m2 stops
Multiple Airlines Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$506Multiple Airlines
Sat, Feb 21 - Sat, Feb 28
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Avianca Logo
4:45 pm - 8:55 am
CUZ
-
PTY
16h 10m1 stop
$546Avianca
Wed, Jan 28 - Mon, Mar 30
Multiple Airlines Logo
2:55 pm - 8:25 am
PTY
-
CUZ
17h 30m3 stops
Multiple Airlines Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$571Multiple Airlines
Sat, Feb 21 - Sat, Feb 28
Multiple Airlines Logo
2:55 am - 9:05 pm
PTY
-
CUZ
18h 10m2 stops
Multiple Airlines Logo
7:05 am - 4:55 pm
CUZ
-
PTY
33h 50m2 stops
$664Multiple Airlines
Mon, Feb 2 - Tue, Feb 10

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
Feb 1
PTY5:50 pmPanama City Tocumen Intl
17h 30m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 7
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$400
Avianca
Feb 3
PTY5:50 pmPanama City Tocumen Intl
17h 30m
1 stop
CUZ11:20 amCusco Velazco Astete
Feb 10
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$410
Avianca
Jan 31
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 7
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$451

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 2/1

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Sat 3/7

5:10 pm-1:00 am

1 stop7h 50m

$400

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 2/3

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Tue 2/10

5:10 pm-1:00 am

1 stop7h 50m

$410

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 1/31

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sat 3/7

5:10 pm-1:00 am

1 stop7h 50m

$451

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 2/3

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Tue 2/10

9:45 pm-8:50 am

2 stops11h 05m

$462

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 3/4

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Sat 3/7

9:37 pm-8:50 am

2 stops11h 13m

$497

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 2/28

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Wed 3/4

9:27 pm-8:50 am

2 stops11h 23m

$499

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 2/21

9:45 am-9:15 pm

2 stops11h 30m

Cusco Velazco Astete

Sat 2/28

5:10 pm-1:00 am

1 stop7h 50m

$506

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 1/28

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Mon 3/30

4:45 pm-8:55 am

1 stop16h 10m

$546

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 2/21

2:55 pm-8:25 am

3 stops17h 30m

Cusco Velazco Astete

Sat 2/28

5:10 pm-1:00 am

1 stop7h 50m

$571

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Mon 2/2

2:55 am-9:05 pm

2 stops18h 10m

Cusco Velazco Astete

Tue 2/10

7:05 am-4:55 pm

2 stops33h 50m

$664

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you aren’t able to travel to Cusco during the month of February, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $375.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $419 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $375 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

11h 30m

Direct flights

None
The fastest flight from Panama City to Cusco takes 11h 30m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
Search flight deals

  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 11h 30m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $358Free CancellationRating
6.6
2,494 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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