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Cheap flights from Panama City to Cusco from $436

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Avianca Logo
12:25 pm - 12:40 am
CUZ
-
PTY
12h 15m1 stop
$436Avianca
Tue, Jan 20 - Wed, Jan 28
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$453Avianca
Sat, Jan 10 - Thu, Jan 15
Avianca Logo
10:05 pm - 11:00 am
PTY
-
CUZ
12h 55m1 stop
Avianca Logo
12:15 pm - 12:10 am
CUZ
-
PTY
11h 55m1 stop
$519Avianca
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Multiple Airlines Logo
9:37 pm - 2:00 pm
CUZ
-
PTY
16h 23m2 stops
$605Multiple Airlines
Fri, Mar 6 - Sat, Mar 7
Multiple Airlines Logo
10:05 pm - 11:00 am
PTY
-
CUZ
12h 55m1 stop
Multiple Airlines Logo
6:57 am - 4:30 pm
CUZ
-
PTY
33h 33m2 stops
$621Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
9:45 am - 7:41 pm
PTY
-
CUZ
9h 56m2 stops
Multiple Airlines Logo
9:47 pm - 2:00 pm
CUZ
-
PTY
16h 13m2 stops
$704Multiple Airlines
Sat, Mar 7 - Sat, Mar 7
Multiple Airlines Logo
9:55 am - 10:25 pm
PTY
-
CUZ
12h 30m2 stops
Multiple Airlines Logo
6:57 am - 4:30 pm
CUZ
-
PTY
33h 33m2 stops
$705Multiple Airlines
Thu, Apr 30 - Sun, May 3
Multiple Airlines Logo
2:55 am - 4:31 pm
PTY
-
CUZ
13h 36m2 stops
Multiple Airlines Logo
7:50 pm - 8:50 am
CUZ
-
PTY
13h 00m3 stops
$857Multiple Airlines
Fri, Mar 6 - Sat, Mar 7
Avianca Logo
7:50 pm - 11:20 am
PTY
-
CUZ
15h 30m2 stops
Avianca Logo
12:25 pm - 12:40 am
CUZ
-
PTY
12h 15m1 stop
$863Avianca
Wed, Jan 21 - Wed, Jan 28
Multiple Airlines Logo
3:20 am - 10:25 pm
PTY
-
CUZ
19h 05m2 stops
Multiple Airlines Logo
7:50 pm - 10:10 am
CUZ
-
PTY
14h 20m3 stops
$900Multiple Airlines
Wed, Apr 29 - Sun, May 3

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
Jan 20
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Jan 28
CUZ12:25 pmCusco Velazco Astete
12h 15m
1 stop
PTY12:40 amPanama City Tocumen Intl
$436
Find similar
Avianca
Jan 10
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Jan 15
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$453
Find similar
Avianca
Apr 30
PTY10:05 pmPanama City Tocumen Intl
12h 55m
1 stop
CUZ11:00 amCusco Velazco Astete
May 3
CUZ12:15 pmCusco Velazco Astete
11h 55m
1 stop
PTY12:10 amPanama City Tocumen Intl
$519
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 1/20

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Wed 1/28

12:25 pm-12:40 am

1 stop12h 15m

$436

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 1/10

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Thu 1/15

5:10 pm-1:00 am

1 stop7h 50m

$453

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 4/30

10:05 pm-11:00 am

1 stop12h 55m

Cusco Velazco Astete

Sun 5/3

12:15 pm-12:10 am

1 stop11h 55m

$519

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 3/6

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sat 3/7

9:37 pm-2:00 pm

2 stops16h 23m

$605

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 4/30

10:05 pm-11:00 am

1 stop12h 55m

Cusco Velazco Astete

Sun 5/3

6:57 am-4:30 pm

2 stops33h 33m

$621

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 3/7

9:45 am-7:41 pm

2 stops9h 56m

Cusco Velazco Astete

Sat 3/7

9:47 pm-2:00 pm

2 stops16h 13m

$704

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 4/30

9:55 am-10:25 pm

2 stops12h 30m

Cusco Velazco Astete

Sun 5/3

6:57 am-4:30 pm

2 stops33h 33m

$705

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 3/6

2:55 am-4:31 pm

2 stops13h 36m

Cusco Velazco Astete

Sat 3/7

7:50 pm-8:50 am

3 stops13h 00m

$857

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 1/21

7:50 pm-11:20 am

2 stops15h 30m

Cusco Velazco Astete

Wed 1/28

12:25 pm-12:40 am

1 stop12h 15m

$863

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 4/29

3:20 am-10:25 pm

2 stops19h 05m

Cusco Velazco Astete

Sun 5/3

7:50 pm-10:10 am

3 stops14h 20m

$900

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you aren’t able to travel to Cusco during the month of February, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $371.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart from Panama City to Cusco is on a Wednesday when prices can be found for as low as $439. The most expensive day to fly to Cusco is Monday, with ticket prices averaging around $459.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $418 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $381 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

12h 20m

Direct flights

None
The fastest flight from Panama City to Cusco takes 12h 20m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
Search flight deals

  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 12h 20m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $358Free CancellationRating
6.6
2,490 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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