Cheap flights from Panama City to Cusco from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 4/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m
1 stop
$411Avianca
Mon, Mar 16 - Tue, Mar 24
Avianca Logo
3:05 am - 11:20 am
PTY
-
CUZ
8h 15m
1 stop
Avianca Logo
5:10 pm - 1:05 am
CUZ
-
PTY
7h 55m
1 stop
$426Avianca
Sat, May 9 - Tue, May 19
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
5:10 pm - 5:00 pm
CUZ
-
PTY
23h 50m
1 stop
$433Avianca
Thu, Mar 19 - Fri, Apr 24
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
12:25 pm - 4:55 pm
CUZ
-
PTY
28h 30m
1 stop
$450Avianca
Thu, Mar 12 - Fri, Mar 20
Avianca Logo
3:10 pm - 11:20 am
PTY
-
CUZ
20h 10m
1 stop
Avianca Logo
5:10 pm - 2:15 pm
CUZ
-
PTY
21h 05m
1 stop
$461Avianca
Fri, Apr 17 - Sun, Apr 19
Multiple Airlines Logo
5:55 pm - 11:20 am
PTY
-
CUZ
17h 25m
1 stop
Multiple Airlines Logo
7:55 am - 2:15 pm
CUZ
-
PTY
30h 20m
2 stops
$481Multiple Airlines
Sun, May 10 - Tue, May 19
Multiple Airlines Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Multiple Airlines Logo
10:25 pm - 1:05 am
CUZ
-
PTY
26h 40m
2 stops
$482Multiple Airlines
Thu, Mar 19 - Fri, Apr 24
Multiple Airlines Logo
2:55 am - 9:26 pm
PTY
-
CUZ
18h 31m
2 stops
Multiple Airlines Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m
1 stop
$521Multiple Airlines
Mon, Mar 16 - Tue, Mar 24
Multiple Airlines Logo
5:50 pm - 9:11 pm
PTY
-
CUZ
27h 21m
2 stops
Multiple Airlines Logo
6:50 am - 1:05 am
CUZ
-
PTY
18h 15m
2 stops
$528Multiple Airlines
Fri, Mar 20 - Fri, Apr 24
Multiple Airlines Logo
9:45 am - 9:26 pm
PTY
-
CUZ
11h 41m
2 stops
Multiple Airlines Logo
11:02 am - 1:00 am
CUZ
-
PTY
13h 58m
2 stops
$579Multiple Airlines
Tue, Mar 17 - Tue, Mar 24

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
Feb 19
PTY5:50 pmPanama City Tocumen Intl
17h 30m
1 stop
CUZ11:20 amCusco Velazco Astete
Feb 25
CUZ12:25 pmCusco Velazco Astete
12h 15m
1 stop
PTY12:40 amPanama City Tocumen Intl
$401
Avianca
Mar 16
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 24
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$411
Avianca
Jul 23
PTY5:55 pmPanama City Tocumen Intl
17h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Jul 30
CUZ5:10 pmCusco Velazco Astete
16h 05m
1 stop
PTY9:15 amPanama City Tocumen Intl
$426

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Mon 3/16

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Tue 3/24

5:10 pm-1:00 am

1 stop7h 50m

$411

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

3:05 am-11:20 am

1 stop8h 15m

Cusco Velazco Astete

Tue 5/19

5:10 pm-1:05 am

1 stop7h 55m

$426

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 3/19

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Fri 4/24

5:10 pm-5:00 pm

1 stop23h 50m

$433

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 3/12

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Fri 3/20

12:25 pm-4:55 pm

1 stop28h 30m

$450

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 4/17

3:10 pm-11:20 am

1 stop20h 10m

Cusco Velazco Astete

Sun 4/19

5:10 pm-2:15 pm

1 stop21h 05m

$461

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/10

5:55 pm-11:20 am

1 stop17h 25m

Cusco Velazco Astete

Tue 5/19

7:55 am-2:15 pm

2 stops30h 20m

$481

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 3/19

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Fri 4/24

10:25 pm-1:05 am

2 stops26h 40m

$482

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Mon 3/16

2:55 am-9:26 pm

2 stops18h 31m

Cusco Velazco Astete

Tue 3/24

5:10 pm-1:00 am

1 stop7h 50m

$521

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 3/20

5:50 pm-9:11 pm

2 stops27h 21m

Cusco Velazco Astete

Fri 4/24

6:50 am-1:05 am

2 stops18h 15m

$528

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 3/17

9:45 am-9:26 pm

2 stops11h 41m

Cusco Velazco Astete

Tue 3/24

11:02 am-1:00 am

2 stops13h 58m

$579

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $391. If you aren’t able to travel to Cusco during the month of February, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $393.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $424 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $381 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

10h 50m

Direct flights

None
The fastest flight from Panama City to Cusco takes 10h 50m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 10h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $369Free CancellationRating
6.6
2,496 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Fri 3/20
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