Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Cusco from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
5:10 pm - 8:50 am
CUZ
-
PTY
15h 40m
1 stop
$400Avianca
Thu, Feb 19 - Sat, Mar 7
Avianca Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m
1 stop
Avianca Logo
12:25 pm - 12:40 am
CUZ
-
PTY
12h 15m
1 stop
$410Avianca
Wed, Mar 4 - Wed, Mar 25
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m
1 stop
$451Avianca
Sat, Jan 31 - Sat, Mar 7
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
5:10 pm - 8:50 am
CUZ
-
PTY
15h 40m
1 stop
$494Avianca
Sat, Jan 31 - Sat, Mar 7
Avianca Logo
11:25 am - 11:20 am
PTY
-
CUZ
23h 55m
2 stops
Avianca Logo
12:25 pm - 12:40 am
CUZ
-
PTY
12h 15m
1 stop
$553Avianca
Wed, Mar 4 - Wed, Mar 25
Avianca Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m
1 stop
Avianca Logo
5:10 pm - 8:50 am
CUZ
-
PTY
15h 40m
1 stop
$557Avianca
Mon, Feb 9 - Mon, Feb 16
Multiple Airlines Logo
2:55 am - 9:01 pm
PTY
-
CUZ
18h 06m
2 stops
Multiple Airlines Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m
1 stop
$598Multiple Airlines
Thu, Feb 19 - Sat, Mar 7
Multiple Airlines Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Multiple Airlines Logo
9:32 pm - 8:50 am
CUZ
-
PTY
11h 18m
2 stops
$619Multiple Airlines
Tue, Mar 3 - Wed, Mar 25
Multiple Airlines Logo
5:50 pm - 11:20 am
PTY
-
CUZ
17h 30m
1 stop
Multiple Airlines Logo
6:40 pm - 8:50 am
CUZ
-
PTY
14h 10m
2 stops
$643Multiple Airlines
Mon, Feb 9 - Mon, Feb 16
Multiple Airlines Logo
11:25 am - 11:20 am
PTY
-
CUZ
23h 55m
2 stops
Multiple Airlines Logo
7:02 am - 8:50 am
CUZ
-
PTY
25h 48m
3 stops
$664Multiple Airlines
Wed, Mar 4 - Wed, Mar 25

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
Feb 19
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 7
CUZ5:10 pmCusco Velazco Astete
15h 40m
1 stop
PTY8:50 amPanama City Tocumen Intl
$400
Avianca
Jan 29
PTY5:50 pmPanama City Tocumen Intl
17h 30m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 30
CUZ4:45 pmCusco Velazco Astete
8h 00m
1 stop
PTY12:45 amPanama City Tocumen Intl
$410
Avianca
Jan 31
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 7
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$451

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 2/19

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sat 3/7

5:10 pm-8:50 am

1 stop15h 40m

$400

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 3/4

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Wed 3/25

12:25 pm-12:40 am

1 stop12h 15m

$410

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 1/31

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sat 3/7

5:10 pm-1:00 am

1 stop7h 50m

$451

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 1/31

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sat 3/7

5:10 pm-8:50 am

1 stop15h 40m

$494

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 3/4

11:25 am-11:20 am

2 stops23h 55m

Cusco Velazco Astete

Wed 3/25

12:25 pm-12:40 am

1 stop12h 15m

$553

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Mon 2/9

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Mon 2/16

5:10 pm-8:50 am

1 stop15h 40m

$557

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 2/19

2:55 am-9:01 pm

2 stops18h 06m

Cusco Velazco Astete

Sat 3/7

5:10 pm-1:00 am

1 stop7h 50m

$598

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 3/3

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Wed 3/25

9:32 pm-8:50 am

2 stops11h 18m

$619

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Mon 2/9

5:50 pm-11:20 am

1 stop17h 30m

Cusco Velazco Astete

Mon 2/16

6:40 pm-8:50 am

2 stops14h 10m

$643

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 3/4

11:25 am-11:20 am

2 stops23h 55m

Cusco Velazco Astete

Wed 3/25

7:02 am-8:50 am

3 stops25h 48m

$664

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Cusco?

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you aren’t able to travel to Cusco during the month of February, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $380.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $419 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $381 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

11h 16m

Direct flights

None
The fastest flight from Panama City to Cusco takes 11h 16m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
Search flight deals

  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 11h 16m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $368Free CancellationRating
6.6
2,496 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Cusco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 2/21
Sat 2/28
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Peru