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Cheap flights from Panama City to Cusco from $412

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Cusco (PTY-CUZ)

Cheap round-trip flights

Avianca Logo
5:55 pm - 11:20 amPTY-CUZ
17h 25m1 stop
Avianca Logo
5:10 pm - 8:50 amCUZ-PTY
15h 40m1 stop
$412Avianca
Find Deal
Sat, Nov 1 - Thu, Nov 6
Avianca Logo
5:55 pm - 11:20 amPTY-CUZ
17h 25m1 stop
Avianca Logo
5:10 pm - 8:50 amCUZ-PTY
15h 40m1 stop
$417Avianca
Find Deal
Sat, Nov 1 - Thu, Nov 6
Avianca Logo
5:55 pm - 11:20 amPTY-CUZ
17h 25m1 stop
Avianca Logo
12:25 pm - 12:40 amCUZ-PTY
12h 15m1 stop
$485Avianca
Find Deal
Mon, Oct 27 - Fri, Oct 31
Avianca Logo
2:55 am - 11:20 amPTY-CUZ
8h 25m1 stop
Avianca Logo
12:25 pm - 12:40 amCUZ-PTY
12h 15m1 stop
$496Avianca
Find Deal
Sun, Oct 26 - Fri, Oct 31
Avianca Logo
2:55 am - 11:20 amPTY-CUZ
8h 25m1 stop
Avianca Logo
12:25 pm - 12:40 amCUZ-PTY
12h 15m1 stop
$511Avianca
Find Deal
Sun, Oct 26 - Fri, Oct 31
Avianca Logo
3:20 am - 11:00 amPTY-CUZ
7h 40m1 stop
Avianca Logo
12:15 pm - 9:10 pmCUZ-PTY
8h 55m1 stop
$536Avianca
Find Deal
Thu, Oct 9 - Fri, Oct 17
Avianca Logo
9:45 am - 11:20 amPTY-CUZ
25h 35m1 stop
Avianca Logo
12:25 pm - 8:50 amCUZ-PTY
20h 25m1 stop
$573Avianca
Find Deal
Sat, Nov 1 - Wed, Nov 5
Avianca Logo
9:45 am - 11:20 amPTY-CUZ
25h 35m1 stop
Avianca Logo
12:25 pm - 8:50 amCUZ-PTY
20h 25m1 stop
$583Avianca
Find Deal
Sat, Nov 1 - Wed, Nov 5
Logo
12:05 pm - 10:00 pmPTY-CUZ
9h 55m1 stop
Logo
11:35 pm - 2:44 pmCUZ-PTY
15h 09m1 stop
$635
Find Deal
Fri, Oct 10 - Fri, Oct 17
Logo
3:20 am - 8:19 pmPTY-CUZ
16h 59m2 stops
Logo
12:15 pm - 9:10 pmCUZ-PTY
8h 55m1 stop
$639
Find Deal
Thu, Oct 9 - Fri, Oct 17

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
Nov 1
PTY5:55 pmPanama City Tocumen Intl
17h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Nov 6
CUZ5:10 pmCusco Velazco Astete
15h 40m
1 stop
PTY8:50 amPanama City Tocumen Intl
$412
Find similar
Avianca
Nov 1
PTY5:55 pmPanama City Tocumen Intl
17h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Nov 6
CUZ5:10 pmCusco Velazco Astete
15h 40m
1 stop
PTY8:50 amPanama City Tocumen Intl
$417
Find similar
Avianca
Oct 27
PTY5:55 pmPanama City Tocumen Intl
17h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Oct 31
CUZ12:25 pmCusco Velazco Astete
12h 15m
1 stop
PTY12:40 amPanama City Tocumen Intl
$485
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 27, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 11/1

5:55 pm-11:20 am

1 stop17h 25m

Cusco Velazco Astete

Thu 11/6

5:10 pm-8:50 am

1 stop15h 40m

$412

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 11/1

5:55 pm-11:20 am

1 stop17h 25m

Cusco Velazco Astete

Thu 11/6

5:10 pm-8:50 am

1 stop15h 40m

$417

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Mon 10/27

5:55 pm-11:20 am

1 stop17h 25m

Cusco Velazco Astete

Fri 10/31

12:25 pm-12:40 am

1 stop12h 15m

$485

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 10/26

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Fri 10/31

12:25 pm-12:40 am

1 stop12h 15m

$496

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 10/26

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Fri 10/31

12:25 pm-12:40 am

1 stop12h 15m

$511

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 10/9

3:20 am-11:00 am

1 stop7h 40m

Cusco Velazco Astete

Fri 10/17

12:15 pm-9:10 pm

1 stop8h 55m

$536

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 11/1

9:45 am-11:20 am

1 stop25h 35m

Cusco Velazco Astete

Wed 11/5

12:25 pm-8:50 am

1 stop20h 25m

$573

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 11/1

9:45 am-11:20 am

1 stop25h 35m

Cusco Velazco Astete

Wed 11/5

12:25 pm-8:50 am

1 stop20h 25m

$583

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 10/10

12:05 pm-10:00 pm

1 stop9h 55m

Cusco Velazco Astete

Fri 10/17

11:35 pm-2:44 pm

1 stop15h 09m

$635

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 10/9

3:20 am-8:19 pm

2 stops16h 59m

Cusco Velazco Astete

Fri 10/17

12:15 pm-9:10 pm

1 stop8h 55m

$639

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $358. If you aren’t able to travel to Cusco during the month of February, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $364.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart from Panama City to Cusco is on a Wednesday when prices can be found for as low as $439. The most expensive day to fly to Cusco is Monday, with ticket prices averaging around $459.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $404 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $369 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Direct flights

None
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
Search flight deals

  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 7h 40m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $358Free CancellationRating
6.7
2,419 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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