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Cheap flights from Panama City to Cusco from $410

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 5/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
10:05 pm - 11:00 am
PTY
-
CUZ
12h 55m
1 stop
Avianca Logo
4:45 pm - 10:10 am
CUZ
-
PTY
17h 25m
1 stop
$410Avianca
Sun, May 31 - Sat, Jun 6
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m
1 stop
Avianca Logo
12:25 pm - 1:00 am
CUZ
-
PTY
12h 35m
1 stop
$494Avianca
Thu, Feb 19 - Sun, Feb 22
Avianca Logo
3:20 am - 11:00 am
PTY
-
CUZ
7h 40m
1 stop
Avianca Logo
4:45 pm - 12:45 am
CUZ
-
PTY
8h 00m
1 stop
$504Avianca
Thu, Jun 11 - Mon, Jun 22
Avianca Logo
11:25 am - 11:00 am
PTY
-
CUZ
23h 35m
2 stops
Avianca Logo
4:45 pm - 12:10 am
CUZ
-
PTY
7h 25m
1 stop
$629Avianca
Sun, May 31 - Sat, Jun 6
Multiple Airlines Logo
3:20 am - 11:00 am
PTY
-
CUZ
7h 40m
1 stop
Multiple Airlines Logo
10:30 pm - 12:10 am
CUZ
-
PTY
25h 40m
2 stops
$639Multiple Airlines
Thu, Jun 11 - Mon, Jun 22
Avianca Logo
7:50 pm - 11:20 am
PTY
-
CUZ
15h 30m
2 stops
Avianca Logo
12:25 pm - 1:00 am
CUZ
-
PTY
12h 35m
1 stop
$676Avianca
Fri, Feb 20 - Sun, Feb 22
Multiple Airlines Logo
10:05 pm - 6:35 am
PTY
-
CUZ
32h 30m
3 stops
Multiple Airlines Logo
4:45 pm - 8:55 am
CUZ
-
PTY
16h 10m
1 stop
$712Multiple Airlines
Fri, Jun 12 - Mon, Jun 22
Avianca Logo
11:25 am - 11:00 am
PTY
-
CUZ
23h 35m
2 stops
Avianca Logo
4:45 pm - 2:55 pm
CUZ
-
PTY
22h 10m
2 stops
$844Avianca
Sun, May 31 - Sat, Jun 6
Multiple Airlines Logo
11:05 am - 3:40 pm
PTY
-
CUZ
28h 35m
2 stops
Multiple Airlines Logo
6:00 pm - 8:55 am
CUZ
-
PTY
14h 55m
3 stops
$945Multiple Airlines
Fri, Jun 12 - Mon, Jun 22
Avianca Logo
11:25 am - 11:00 am
PTY
-
CUZ
23h 35m
2 stops
Avianca Logo
4:45 pm - 2:55 pm
CUZ
-
PTY
22h 10m
3 stops
$1,209Avianca
Sun, May 31 - Sat, Jun 6

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
May 31
PTY10:05 pmPanama City Tocumen Intl
12h 55m
1 stop
CUZ11:00 amCusco Velazco Astete
Jun 6
CUZ4:45 pmCusco Velazco Astete
17h 25m
1 stop
PTY10:10 amPanama City Tocumen Intl
$410
Avianca
Jan 28
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 30
CUZ4:45 pmCusco Velazco Astete
8h 00m
1 stop
PTY12:45 amPanama City Tocumen Intl
$425
Avianca
Jan 31
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Mar 7
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$494

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

10:05 pm-11:00 am

1 stop12h 55m

Cusco Velazco Astete

Sat 6/6

4:45 pm-10:10 am

1 stop17h 25m

$410

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 2/19

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sun 2/22

12:25 pm-1:00 am

1 stop12h 35m

$494

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 6/11

3:20 am-11:00 am

1 stop7h 40m

Cusco Velazco Astete

Mon 6/22

4:45 pm-12:45 am

1 stop8h 00m

$504

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

11:25 am-11:00 am

2 stops23h 35m

Cusco Velazco Astete

Sat 6/6

4:45 pm-12:10 am

1 stop7h 25m

$629

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 6/11

3:20 am-11:00 am

1 stop7h 40m

Cusco Velazco Astete

Mon 6/22

10:30 pm-12:10 am

2 stops25h 40m

$639

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 2/20

7:50 pm-11:20 am

2 stops15h 30m

Cusco Velazco Astete

Sun 2/22

12:25 pm-1:00 am

1 stop12h 35m

$676

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 6/12

10:05 pm-6:35 am

3 stops32h 30m

Cusco Velazco Astete

Mon 6/22

4:45 pm-8:55 am

1 stop16h 10m

$712

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

11:25 am-11:00 am

2 stops23h 35m

Cusco Velazco Astete

Sat 6/6

4:45 pm-2:55 pm

2 stops22h 10m

$844

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 6/12

11:05 am-3:40 pm

2 stops28h 35m

Cusco Velazco Astete

Mon 6/22

6:00 pm-8:55 am

3 stops14h 55m

$945

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

11:25 am-11:00 am

2 stops23h 35m

Cusco Velazco Astete

Sat 6/6

4:45 pm-2:55 pm

3 stops22h 10m

$1,209

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you aren’t able to travel to Cusco during the month of February, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $380.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $420 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $381 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

12h 40m

Direct flights

None
The fastest flight from Panama City to Cusco takes 12h 40m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
Search flight deals

  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 12h 40m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $369Free CancellationRating
6.6
2,487 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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