Cheap flights from Panama City to Cusco from $258

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 4/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
5:55 pm - 11:20 am
PTY
-
CUZ
17h 25m
1 stop
Avianca Logo
5:10 pm - 12:35 am
CUZ
-
PTY
7h 25m
1 stop
$465Avianca
Sat, May 30 - Mon, Jun 8
Avianca Logo
4:25 am - 11:20 am
PTY
-
CUZ
6h 55m
1 stop
Avianca Logo
5:10 pm - 12:35 am
CUZ
-
PTY
7h 25m
1 stop
$484Avianca
Sun, May 31 - Mon, Jun 8
Multiple Airlines Logo
10:10 am - 9:16 pm
PTY
-
CUZ
11h 06m
2 stops
Multiple Airlines Logo
5:10 pm - 12:35 am
CUZ
-
PTY
7h 25m
1 stop
$540Multiple Airlines
Wed, May 27 - Mon, Jun 8
Multiple Airlines Logo
4:25 am - 11:20 am
PTY
-
CUZ
6h 55m
1 stop
Multiple Airlines Logo
9:55 pm - 9:15 am
CUZ
-
PTY
11h 20m
2 stops
$563Multiple Airlines
Sun, May 31 - Tue, Jun 9
Multiple Airlines Logo
4:25 am - 4:35 pm
PTY
-
CUZ
12h 10m
2 stops
Multiple Airlines Logo
5:10 pm - 12:35 am
CUZ
-
PTY
7h 25m
1 stop
$564Multiple Airlines
Fri, May 29 - Mon, Jun 8
Multiple Airlines Logo
4:25 am - 11:20 am
PTY
-
CUZ
6h 55m
1 stop
Multiple Airlines Logo
10:05 pm - 9:15 am
CUZ
-
PTY
11h 10m
2 stops
$565Multiple Airlines
Sun, May 31 - Sun, Jun 7
Multiple Airlines Logo
4:25 am - 8:35 pm
PTY
-
CUZ
16h 10m
2 stops
Multiple Airlines Logo
4:35 pm - 9:15 am
CUZ
-
PTY
16h 40m
2 stops
$568Multiple Airlines
Fri, Jun 5 - Tue, Jun 9
Multiple Airlines Logo
10:10 am - 7:20 pm
PTY
-
CUZ
9h 10m
2 stops
Multiple Airlines Logo
5:10 pm - 12:35 am
CUZ
-
PTY
7h 25m
1 stop
$572Multiple Airlines
Thu, Sep 17 - Tue, Sep 22
Avianca Logo
4:25 am - 11:20 am
PTY
-
CUZ
6h 55m
1 stop
Avianca Logo
5:10 pm - 12:35 am
CUZ
-
PTY
7h 25m
1 stop
$583Avianca
Thu, May 28 - Mon, Jun 8
Avianca Logo
3:10 pm - 11:20 am
PTY
-
CUZ
20h 10m
1 stop
Avianca Logo
5:10 pm - 2:15 pm
CUZ
-
PTY
21h 05m
1 stop
$610Avianca
Wed, May 27 - Mon, Jun 8

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
May 30
PTY5:55 pmPanama City Tocumen Intl
17h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Jun 8
CUZ5:10 pmCusco Velazco Astete
7h 25m
1 stop
PTY12:35 amPanama City Tocumen Intl
$465
Avianca
May 31
PTY4:25 amPanama City Tocumen Intl
6h 55m
1 stop
CUZ11:20 amCusco Velazco Astete
Jun 8
CUZ5:10 pmCusco Velazco Astete
7h 25m
1 stop
PTY12:35 amPanama City Tocumen Intl
$484
Avianca
May 28
PTY4:25 amPanama City Tocumen Intl
6h 55m
1 stop
CUZ11:20 amCusco Velazco Astete
Jun 8
CUZ5:10 pmCusco Velazco Astete
7h 25m
1 stop
PTY12:35 amPanama City Tocumen Intl
$583

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/30

5:55 pm-11:20 am

1 stop17h 25m

Cusco Velazco Astete

Mon 6/8

5:10 pm-12:35 am

1 stop7h 25m

$465
Quickest round-trip

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

4:25 am-11:20 am

1 stop6h 55m

Cusco Velazco Astete

Mon 6/8

5:10 pm-12:35 am

1 stop7h 25m

$484

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 5/27

10:10 am-9:16 pm

2 stops11h 06m

Cusco Velazco Astete

Mon 6/8

5:10 pm-12:35 am

1 stop7h 25m

$540

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

4:25 am-11:20 am

1 stop6h 55m

Cusco Velazco Astete

Tue 6/9

9:55 pm-9:15 am

2 stops11h 20m

$563

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 5/29

4:25 am-4:35 pm

2 stops12h 10m

Cusco Velazco Astete

Mon 6/8

5:10 pm-12:35 am

1 stop7h 25m

$564

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 5/31

4:25 am-11:20 am

1 stop6h 55m

Cusco Velazco Astete

Sun 6/7

10:05 pm-9:15 am

2 stops11h 10m

$565

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 6/5

4:25 am-8:35 pm

2 stops16h 10m

Cusco Velazco Astete

Tue 6/9

4:35 pm-9:15 am

2 stops16h 40m

$568

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 9/17

10:10 am-7:20 pm

2 stops9h 10m

Cusco Velazco Astete

Tue 9/22

5:10 pm-12:35 am

1 stop7h 25m

$572

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 5/28

4:25 am-11:20 am

1 stop6h 55m

Cusco Velazco Astete

Mon 6/8

5:10 pm-12:35 am

1 stop7h 25m

$583

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 5/27

3:10 pm-11:20 am

1 stop20h 10m

Cusco Velazco Astete

Mon 6/8

5:10 pm-2:15 pm

1 stop21h 05m

$610

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Cusco?

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $390. If you aren’t able to travel to Cusco during the month of February, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $397.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $424 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $381 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

6h 55m

Direct flights

None
The fastest flight from Panama City to Cusco takes 6h 55m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 6h 55m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $369Free CancellationRating
6.5
2,505 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Cusco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 4/24
Fri 5/1

Find better results for your trip to Peru