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Cheap flights from Panama City to Cusco from $451

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Cusco departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City to Cusco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Avianca Logo
5:10 pm - 1:00 am
CUZ
-
PTY
7h 50m1 stop
$451Avianca
Sun, Jan 11 - Tue, Jan 20
Avianca Logo
10:05 pm - 11:00 am
PTY
-
CUZ
12h 55m1 stop
Avianca Logo
4:45 pm - 10:10 am
CUZ
-
PTY
17h 25m1 stop
$494Avianca
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
5:25 pm - 11:00 am
PTY
-
CUZ
17h 35m1 stop
Multiple Airlines Logo
4:15 pm - 9:10 pm
CUZ
-
PTY
28h 55m2 stops
$522Multiple Airlines
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
10:05 pm - 11:00 am
PTY
-
CUZ
12h 55m1 stop
Multiple Airlines Logo
10:17 pm - 10:10 am
CUZ
-
PTY
11h 53m2 stops
$535Multiple Airlines
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Multiple Airlines Logo
9:45 pm - 12:40 am
CUZ
-
PTY
26h 55m2 stops
$536Multiple Airlines
Sun, Jan 11 - Tue, Jan 20
Multiple Airlines Logo
2:55 am - 11:20 am
PTY
-
CUZ
8h 25m1 stop
Multiple Airlines Logo
11:02 am - 1:00 am
CUZ
-
PTY
13h 58m2 stops
$547Multiple Airlines
Sun, Jan 11 - Tue, Jan 20
Multiple Airlines Logo
3:25 am - 8:34 pm
PTY
-
CUZ
17h 09m2 stops
Multiple Airlines Logo
10:17 pm - 4:30 pm
CUZ
-
PTY
18h 13m2 stops
$691Multiple Airlines
Fri, May 8 - Sat, May 16
Multiple Airlines Logo
1:30 pm - 11:00 am
PTY
-
CUZ
21h 30m2 stops
Multiple Airlines Logo
4:15 pm - 9:10 pm
CUZ
-
PTY
28h 55m2 stops
$700Multiple Airlines
Sat, May 9 - Sat, May 16
Multiple Airlines Logo
9:45 pm - 6:24 am
PTY
-
CUZ
8h 39m1 stop
Multiple Airlines Logo
12:05 am - 7:39 am
CUZ
-
PTY
7h 34m1 stop
$703Multiple Airlines
Sat, May 9 - Fri, May 15
Multiple Airlines Logo
8:10 pm - 11:00 am
PTY
-
CUZ
14h 50m3 stops
Multiple Airlines Logo
8:02 am - 10:10 am
CUZ
-
PTY
26h 08m2 stops
$836Multiple Airlines
Sat, May 9 - Sat, May 16

Avianca flights from Panama City to Cusco

Our best Avianca deals on Panama City to Cusco flight tickets
Avianca
Jan 11
PTY2:55 amPanama City Tocumen Intl
8h 25m
1 stop
CUZ11:20 amCusco Velazco Astete
Jan 20
CUZ5:10 pmCusco Velazco Astete
7h 50m
1 stop
PTY1:00 amPanama City Tocumen Intl
$451
Find similar
Avianca
May 9
PTY10:05 pmPanama City Tocumen Intl
12h 55m
1 stop
CUZ11:00 amCusco Velazco Astete
May 16
CUZ4:45 pmCusco Velazco Astete
17h 25m
1 stop
PTY10:10 amPanama City Tocumen Intl
$494
Find similar
Avianca
Jan 12
PTY7:50 pmPanama City Tocumen Intl
15h 30m
2 stops
CUZ11:20 amCusco Velazco Astete
Jan 20
CUZ5:10 pmCusco Velazco Astete
25h 45m
2 stops
PTY6:55 pmPanama City Tocumen Intl
$998
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 1/11

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Tue 1/20

5:10 pm-1:00 am

1 stop7h 50m

$451

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

10:05 pm-11:00 am

1 stop12h 55m

Cusco Velazco Astete

Sat 5/16

4:45 pm-10:10 am

1 stop17h 25m

$494

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

5:25 pm-11:00 am

1 stop17h 35m

Cusco Velazco Astete

Sat 5/16

4:15 pm-9:10 pm

2 stops28h 55m

$522

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

10:05 pm-11:00 am

1 stop12h 55m

Cusco Velazco Astete

Sat 5/16

10:17 pm-10:10 am

2 stops11h 53m

$535

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 1/11

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Tue 1/20

9:45 pm-12:40 am

2 stops26h 55m

$536

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 1/11

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Tue 1/20

11:02 am-1:00 am

2 stops13h 58m

$547

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Fri 5/8

3:25 am-8:34 pm

2 stops17h 09m

Cusco Velazco Astete

Sat 5/16

10:17 pm-4:30 pm

2 stops18h 13m

$691

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

1:30 pm-11:00 am

2 stops21h 30m

Cusco Velazco Astete

Sat 5/16

4:15 pm-9:10 pm

2 stops28h 55m

$700

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

9:45 pm-6:24 am

1 stop8h 39m

Cusco Velazco Astete

Fri 5/15

12:05 am-7:39 am

1 stop7h 34m

$703

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sat 5/9

8:10 pm-11:00 am

3 stops14h 50m

Cusco Velazco Astete

Sat 5/16

8:02 am-10:10 am

2 stops26h 08m

$836

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Cusco from

How to get the cheapest flight ticket from Panama City to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cusco?

In general, February is the cheapest month to fly from Panama City to Cusco. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $371. If you aren’t able to travel to Cusco during the month of February, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $371.

What is the cheapest day to depart on your flight to Cusco?

The cheapest day to depart from Panama City to Cusco is on a Wednesday when prices can be found for as low as $439. The most expensive day to fly to Cusco is Monday, with ticket prices averaging around $459.

How far in advance should I book a flight to Cusco?

You are more likely to see cheaper flights to Cusco from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cusco for around $419 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cusco from Panama City for as low as $381 on momondo.

When to book flights from Panama City to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Cusco (PTY to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Cusco

Fastest flight time

12h 51m

Direct flights

None
The fastest flight from Panama City to Cusco takes 12h 51m
There are no direct flights from Panama City to Cusco. There are no popular flight routes from Panama City to Cusco.
Search flight deals

  • How far is Panama City Tocumen Intl to Cusco Velazco Astete by plane?

    Panama City Tocumen Intl and Cusco Velazco Astete are 1638.7 mi apart from one another. Typically, this will take 12h 51m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The required travel and health documents for your Cusco Velazco Astete Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cusco Velazco Astete Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Panama City to Cusco?

Best airlines flying from Panama City to Cusco

Compare and see reviews for airlines that fly from Panama City to Cusco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $358Free CancellationRating
6.6
2,492 reviews
Search Avianca flights

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Cusco?

Finding the right flight to Cusco from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Cusco quick and easy, saving you time and money.

Can I find flights from Panama City to Cusco with flexible booking policies on momondo?

All flight searches from Panama City to Cusco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Panama City to Cusco?

momondo helps you find the best flight between Panama City and Cusco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Cusco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Cusco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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