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Cheap flights from Panama City, Florida to Greenville from $289

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Greenville departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
7:50 am - 12:15 pm
ECP
-
GSP
3h 25m
1 stop
Southwest Logo
7:00 am - 9:30 am
GSP
-
ECP
3h 30m
1 stop
$307Southwest
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
6:20 pm - 10:45 pm
ECP
-
GSP
3h 25m
1 stop
Southwest Logo
7:00 am - 4:45 pm
GSP
-
ECP
10h 45m
2 stops
$318Southwest
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
1:20 pm - 10:45 pm
ECP
-
GSP
8h 25m
2 stops
Southwest Logo
7:00 am - 4:45 pm
GSP
-
ECP
10h 45m
2 stops
$363Southwest
Thu, Jun 4 - Tue, Jun 9
Delta Logo
6:46 pm - 11:56 pm
ECP
-
GSP
4h 10m
1 stop
Delta Logo
7:59 pm - 11:12 pm
GSP
-
ECP
4h 13m
1 stop
$370Delta
Fri, Apr 17 - Sun, Apr 19
Southwest Logo
12:20 pm - 10:15 pm
ECP
-
GSP
8h 55m
2 stops
Southwest Logo
6:45 am - 9:30 am
GSP
-
ECP
3h 45m
1 stop
$383Southwest
Fri, Apr 10 - Tue, Apr 14
Southwest Logo
12:20 pm - 10:15 pm
ECP
-
GSP
8h 55m
2 stops
Southwest Logo
6:45 am - 2:25 pm
GSP
-
ECP
8h 40m
2 stops
$388Southwest
Fri, Apr 10 - Tue, Apr 14
Southwest Logo
5:25 pm - 10:15 pm
ECP
-
GSP
3h 50m
1 stop
Southwest Logo
6:45 am - 9:30 am
GSP
-
ECP
3h 45m
1 stop
$391Southwest
Fri, Apr 10 - Tue, Apr 14
United Airlines Logo
2:28 pm - 9:53 pm
ECP
-
GSP
6h 25m
1 stop
United Airlines Logo
7:00 am - 2:17 pm
GSP
-
ECP
8h 17m
1 stop
$417United Airlines
Wed, Sep 23 - Sat, Sep 26
United Airlines Logo
10:25 am - 11:05 pm
ECP
-
GSP
11h 40m
2 stops
United Airlines Logo
7:00 am - 2:17 pm
GSP
-
ECP
8h 17m
1 stop
$422United Airlines
Wed, Sep 23 - Sat, Sep 26
Delta Logo
1:33 pm - 8:02 pm
ECP
-
GSP
5h 29m
1 stop
Delta Logo
5:40 am - 8:35 am
GSP
-
ECP
3h 55m
1 stop
$423Delta
Fri, Apr 17 - Sun, Apr 19

Delta flights from Panama City, Florida to Greenville

Our best Delta deals on Panama City, Florida to Greenville flight tickets
Delta
Apr 17
ECP6:46 pmPanama City NW Florida Beaches
4h 10m
1 stop
GSP11:56 pmGreenville
Apr 19
GSP7:59 pmGreenville
4h 13m
1 stop
ECP11:12 pmPanama City NW Florida Beaches
$370
Delta
Apr 17
ECP1:33 pmPanama City NW Florida Beaches
5h 29m
1 stop
GSP8:02 pmGreenville
Apr 19
GSP5:40 amGreenville
3h 55m
1 stop
ECP8:35 amPanama City NW Florida Beaches
$423
Delta
Apr 15
ECP5:49 amPanama City NW Florida Beaches
3h 31m
1 stop
GSP10:20 amGreenville
Apr 15
GSP3:03 pmGreenville
5h 33m
1 stop
ECP7:36 pmPanama City NW Florida Beaches
$509

Southwest flights from Panama City, Florida to Greenville

Our best Southwest deals on Panama City, Florida to Greenville flight tickets
Southwest
Jun 4
ECP7:50 amPanama City NW Florida Beaches
3h 25m
1 stop
GSP12:15 pmGreenville
Jun 9
GSP7:00 amGreenville
3h 30m
1 stop
ECP9:30 amPanama City NW Florida Beaches
$307
Southwest
Jun 4
ECP6:20 pmPanama City NW Florida Beaches
3h 25m
1 stop
GSP10:45 pmGreenville
Jun 9
GSP7:00 amGreenville
10h 45m
2 stops
ECP4:45 pmPanama City NW Florida Beaches
$318
Southwest
Jun 4
ECP1:20 pmPanama City NW Florida Beaches
8h 25m
2 stops
GSP10:45 pmGreenville
Jun 9
GSP7:00 amGreenville
10h 45m
2 stops
ECP4:45 pmPanama City NW Florida Beaches
$363

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Thu 6/4

7:50 am-12:15 pm

1 stop3h 25m

Greenville

Tue 6/9

7:00 am-9:30 am

1 stop3h 30m

$307

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Thu 6/4

6:20 pm-10:45 pm

1 stop3h 25m

Greenville

Tue 6/9

7:00 am-4:45 pm

2 stops10h 45m

$318

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Thu 6/4

1:20 pm-10:45 pm

2 stops8h 25m

Greenville

Tue 6/9

7:00 am-4:45 pm

2 stops10h 45m

$363

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 4/17

6:46 pm-11:56 pm

1 stop4h 10m

Greenville

Sun 4/19

7:59 pm-11:12 pm

1 stop4h 13m

$370

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 4/10

12:20 pm-10:15 pm

2 stops8h 55m

Greenville

Tue 4/14

6:45 am-9:30 am

1 stop3h 45m

$383

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 4/10

12:20 pm-10:15 pm

2 stops8h 55m

Greenville

Tue 4/14

6:45 am-2:25 pm

2 stops8h 40m

$388

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 4/10

5:25 pm-10:15 pm

1 stop3h 50m

Greenville

Tue 4/14

6:45 am-9:30 am

1 stop3h 45m

$391

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Wed 9/23

2:28 pm-9:53 pm

1 stop6h 25m

Greenville

Sat 9/26

7:00 am-2:17 pm

1 stop8h 17m

$417

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Wed 9/23

10:25 am-11:05 pm

2 stops11h 40m

Greenville

Sat 9/26

7:00 am-2:17 pm

1 stop8h 17m

$422

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 4/17

1:33 pm-8:02 pm

1 stop5h 29m

Greenville

Sun 4/19

5:40 am-8:35 am

1 stop3h 55m

$423

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Panama City, Florida to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and Greenville?

When to book flights from Panama City, Florida to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Greenville (ECP to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Greenville

Fastest flight time

3h 13m

Direct flights

None
The fastest flight from Panama City, Florida to Greenville takes 3h 13m
There are no direct flights from Panama City, Florida to Greenville. There are no popular flight routes from Panama City, Florida to Greenville.
Search flight deals

  • How far is Panama City NW Florida Beaches to Greenville by plane?

    Panama City NW Florida Beaches and Greenville are 375.7 mi apart from one another. Typically, this will take 3h 13m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Greenville Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Greenville Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Greenville?

Best airlines flying from Panama City, Florida to Greenville

Compare and see reviews for airlines that fly from Panama City, Florida to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $202Free CancellationRating
7.9
8,359 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Greenville?

Finding the right flight to Greenville from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Panama City to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Panama City with this policy.

How can momondo help me find flights from Panama City to Greenville?

momondo helps you find the best flight between Panama City and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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