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Cheap flights from Panama City, Florida to Greenville from $360

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Greenville departing on 1/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:01 pm - 9:59 pm
ECP
-
GSP
7h 58m1 stop
United Airlines Logo
6:50 am - 12:04 pm
GSP
-
ECP
6h 14m1 stop
$388United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
1:01 pm - 9:59 pm
ECP
-
GSP
7h 58m1 stop
United Airlines Logo
6:30 am - 12:04 pm
GSP
-
ECP
30h 34m2 stops
$528United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
1:01 pm - 9:59 pm
ECP
-
GSP
7h 58m1 stop
United Airlines Logo
10:00 am - 4:11 pm
GSP
-
ECP
31h 11m2 stops
$539United Airlines
Sat, Feb 14 - Wed, Feb 18
United Airlines Logo
1:01 pm - 9:59 pm
ECP
-
GSP
7h 58m1 stop
United Airlines Logo
6:30 am - 7:51 pm
GSP
-
ECP
14h 21m2 stops
$555United Airlines
Sat, Feb 14 - Wed, Feb 18

United Airlines flights from Panama City, Florida to Greenville

Our best United Airlines deals on Panama City, Florida to Greenville flight tickets
United Airlines
Feb 14
ECP1:01 pmPanama City NW Florida Beaches
7h 58m
1 stop
GSP9:59 pmGreenville
Feb 18
GSP6:50 amGreenville
6h 14m
1 stop
ECP12:04 pmPanama City NW Florida Beaches
$388
Find similar
United Airlines
Feb 14
ECP1:01 pmPanama City NW Florida Beaches
7h 58m
1 stop
GSP9:59 pmGreenville
Feb 18
GSP6:30 amGreenville
30h 34m
2 stops
ECP12:04 pmPanama City NW Florida Beaches
$528
Find similar
United Airlines
Feb 14
ECP1:01 pmPanama City NW Florida Beaches
7h 58m
1 stop
GSP9:59 pmGreenville
Feb 18
GSP10:00 amGreenville
31h 11m
2 stops
ECP4:11 pmPanama City NW Florida Beaches
$539
Find similar

American Airlines flights from Panama City, Florida to Greenville

Our best American Airlines deals on Panama City, Florida to Greenville flight tickets
American Airlines
Dec 20
ECP4:09 pmPanama City NW Florida Beaches
4h 45m
1 stop
GSP9:54 pmGreenville
Dec 29
GSP7:00 amGreenville
4h 37m
1 stop
ECP10:37 amPanama City NW Florida Beaches
$868
Find similar
American Airlines
Dec 20
ECP4:09 pmPanama City NW Florida Beaches
6h 49m
1 stop
GSP11:58 pmGreenville
Dec 29
GSP5:00 amGreenville
6h 37m
1 stop
ECP10:37 amPanama City NW Florida Beaches
$891
Find similar
American Airlines
Dec 20
ECP4:09 pmPanama City NW Florida Beaches
6h 49m
1 stop
GSP11:58 pmGreenville
Dec 29
GSP5:00 amGreenville
10h 18m
2 stops
ECP2:18 pmPanama City NW Florida Beaches
$1,359
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-9:59 pm

1 stop7h 58m

Greenville

Wed 2/18

6:50 am-12:04 pm

1 stop6h 14m

$388

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-9:59 pm

1 stop7h 58m

Greenville

Wed 2/18

6:30 am-12:04 pm

2 stops30h 34m

$528

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-9:59 pm

1 stop7h 58m

Greenville

Wed 2/18

10:00 am-4:11 pm

2 stops31h 11m

$539

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Sat 2/14

1:01 pm-9:59 pm

1 stop7h 58m

Greenville

Wed 2/18

6:30 am-7:51 pm

2 stops14h 21m

$555

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 1/2

5:55 pm-9:55 am

2 stops15h 00m

$360

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 1/2

6:00 am-11:58 am

1 stop4h 58m

$460

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Greenville from

How to get the cheapest flight ticket from Panama City, Florida to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Panama City, Florida. The lowest ticket price found for a Wednesday departure recently was $297. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $572. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

When to book flights from Panama City, Florida to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Greenville (ECP to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Greenville

Fastest flight time

6h 02m

Direct flights

None
The fastest flight from Panama City, Florida to Greenville takes 6h 02m
There are no direct flights from Panama City, Florida to Greenville. There are no popular flight routes from Panama City, Florida to Greenville.
Search flight deals

  • How far is Panama City NW Florida Beaches to Greenville by plane?

    Panama City NW Florida Beaches and Greenville are 375.7 mi apart from one another. Typically, this will take 6h 02m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Greenville Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Greenville Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Greenville?

Best airlines flying from Panama City, Florida to Greenville

Compare and see reviews for airlines that fly from Panama City, Florida to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $202Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Greenville?

Finding the right flight to Greenville from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Panama City to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Panama City with this policy.

How can momondo help me find flights from Panama City to Greenville?

momondo helps you find the best flight between Panama City and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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