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Cheap flights from Panama City, Florida to Greenville from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Greenville departing on 9/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Greenville (ECP-GSP)

Cheap round-trip flights

Delta Logo
6:17 pm - 11:54 pmECP-GSP
4h 37m1 stop
Delta Logo
11:04 am - 3:20 pmGSP-ECP
5h 16m1 stop
$203Delta
Find Deal
Mon, Oct 27 - Thu, Oct 30
Delta Logo
9:13 am - 1:28 pmECP-GSP
3h 15m1 stop
Delta Logo
11:04 am - 3:20 pmGSP-ECP
5h 16m1 stop
$229Delta
Find Deal
Fri, Oct 3 - Mon, Oct 6
Delta Logo
7:10 am - 1:20 pmECP-GSP
5h 10m1 stop
Delta Logo
5:30 am - 8:08 amGSP-ECP
3h 38m1 stop
$255Delta
Find Deal
Fri, Sep 5 - Fri, Sep 12
Delta Logo
6:00 am - 12:50 pmECP-GSP
5h 50m1 stop
Delta Logo
10:04 am - 12:33 pmGSP-ECP
3h 29m1 stop
$307Delta
Find Deal
Mon, Oct 20 - Fri, Oct 24
Southwest Logo
2:55 pm - 7:25 pmECP-GSP
3h 30m1 stop
Southwest Logo
1:50 pm - 10:35 pmGSP-ECP
9h 45m2 stops
$324Southwest
Find Deal
Fri, Oct 3 - Mon, Oct 6
Southwest Logo
9:25 am - 7:25 pmECP-GSP
9h 00m2 stops
Southwest Logo
1:50 pm - 10:35 pmGSP-ECP
9h 45m2 stops
$327Southwest
Find Deal
Mon, Oct 27 - Thu, Oct 30
American Airlines Logo
7:10 am - 2:06 pmECP-GSP
5h 56m1 stop
American Airlines Logo
6:40 pm - 11:49 pmGSP-ECP
6h 09m1 stop
$417American Airlines
Find Deal
Tue, Nov 25 - Sat, Nov 29
American Airlines Logo
6:06 pm - 10:55 amECP-GSP
15h 49m2 stops
American Airlines Logo
7:44 pm - 2:18 pmGSP-ECP
19h 34m1 stop
$422American Airlines
Find Deal
Fri, Sep 5 - Fri, Sep 12
United Airlines Logo
2:27 pm - 2:58 pmECP-GSP
23h 31m2 stops
United Airlines Logo
12:34 pm - 1:03 pmGSP-ECP
25h 29m1 stop
$634United Airlines
Find Deal
Wed, Aug 20 - Sun, Aug 24
United Airlines Logo
2:27 pm - 2:58 pmECP-GSP
23h 31m2 stops
United Airlines Logo
4:30 pm - 4:20 pmGSP-ECP
24h 50m2 stops
$689United Airlines
Find Deal
Wed, Aug 20 - Sun, Aug 24

American Airlines flights from Panama City, Florida to Greenville

Our best American Airlines deals on Panama City, Florida to Greenville flight tickets
American Airlines
Nov 25
ECP7:10 amPanama City NW Florida Beaches
5h 56m
1 stop
GSP2:06 pmGreenville
Nov 29
GSP6:40 pmGreenville
6h 09m
1 stop
ECP11:49 pmPanama City NW Florida Beaches
$417
Find similar
American Airlines
Sep 5
ECP6:06 pmPanama City NW Florida Beaches
15h 49m
2 stops
GSP10:55 amGreenville
Sep 12
GSP7:44 pmGreenville
19h 34m
1 stop
ECP2:18 pmPanama City NW Florida Beaches
$422
Find similar
American Airlines
Sep 18
ECP6:59 pmPanama City NW Florida Beaches
3h 53m
1 stop
GSP11:52 pmGreenville
Sep 22
GSP7:44 pmGreenville
19h 36m
1 stop
ECP2:20 pmPanama City NW Florida Beaches
$459
Find similar

Southwest flights from Panama City, Florida to Greenville

Our best Southwest deals on Panama City, Florida to Greenville flight tickets
Southwest
Oct 3
ECP2:55 pmPanama City NW Florida Beaches
3h 30m
1 stop
GSP7:25 pmGreenville
Oct 6
GSP1:50 pmGreenville
9h 45m
2 stops
ECP10:35 pmPanama City NW Florida Beaches
$324
Find similar
Southwest
Oct 27
ECP9:25 amPanama City NW Florida Beaches
9h 00m
2 stops
GSP7:25 pmGreenville
Oct 30
GSP1:50 pmGreenville
9h 45m
2 stops
ECP10:35 pmPanama City NW Florida Beaches
$327
Find similar
Southwest
Oct 27
ECP2:55 pmPanama City NW Florida Beaches
3h 30m
1 stop
GSP7:25 pmGreenville
Oct 30
GSP1:50 pmGreenville
9h 45m
2 stops
ECP10:35 pmPanama City NW Florida Beaches
$332
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 10/27

6:17 pm-11:54 pm

1 stop4h 37m

Greenville

Thu 10/30

11:04 am-3:20 pm

1 stop5h 16m

$203

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 10/3

9:13 am-1:28 pm

1 stop3h 15m

Greenville

Mon 10/6

11:04 am-3:20 pm

1 stop5h 16m

$229

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 9/5

7:10 am-1:20 pm

1 stop5h 10m

Greenville

Fri 9/12

5:30 am-8:08 am

1 stop3h 38m

$255

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 10/20

6:00 am-12:50 pm

1 stop5h 50m

Greenville

Fri 10/24

10:04 am-12:33 pm

1 stop3h 29m

$307

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 10/3

2:55 pm-7:25 pm

1 stop3h 30m

Greenville

Mon 10/6

1:50 pm-10:35 pm

2 stops9h 45m

$324

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Mon 10/27

9:25 am-7:25 pm

2 stops9h 00m

Greenville

Thu 10/30

1:50 pm-10:35 pm

2 stops9h 45m

$327

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Tue 11/25

7:10 am-2:06 pm

1 stop5h 56m

Greenville

Sat 11/29

6:40 pm-11:49 pm

1 stop6h 09m

$417

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Fri 9/5

6:06 pm-10:55 am

2 stops15h 49m

Greenville

Fri 9/12

7:44 pm-2:18 pm

1 stop19h 34m

$422

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Wed 8/20

2:27 pm-2:58 pm

2 stops23h 31m

Greenville

Sun 8/24

12:34 pm-1:03 pm

1 stop25h 29m

$634

Panama CityGreenville

ECP - GSP

ECPGSP

Panama City NW Florida Beaches

Wed 8/20

2:27 pm-2:58 pm

2 stops23h 31m

Greenville

Sun 8/24

4:30 pm-4:20 pm

2 stops24h 50m

$689

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
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See travel insights to Greenville from

How to get the cheapest flight ticket from Panama City, Florida to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Panama City, Florida. The lowest ticket price found for a Wednesday departure recently was $297. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $572. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

When to book flights from Panama City, Florida to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Greenville (ECP to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Greenville

Best Price Found

$102

Fastest flight time

3h 15m

Direct flights

None

Airports in Greenville

1 airport
The best one-way flight to Greenville from Panama City, Florida in the past 72 hours is $102. The best round-trip flight deal from Panama City, Florida to Greenville found on momondo in the last 72 hours is $203.
The fastest flight from Panama City, Florida to Greenville takes 3h 15m
There are no direct flights from Panama City, Florida to Greenville. Popular non-direct route for this connection is Panama City NW Florida Beaches Airport - Greenville Airport.
There is 1 airport near Greenville: Greenville (GSP)
Search flight deals

  • How far is Panama City NW Florida Beaches to Greenville by plane?

    Panama City NW Florida Beaches and Greenville are 375.7 mi apart from one another. Typically, this will take 3h 15m by plane in normal conditions.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Greenville Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Greenville Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Greenville Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Greenville?

Best airlines flying from Panama City, Florida to Greenville

Compare and see reviews for airlines that fly from Panama City, Florida to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $242Free CancellationRating
8.0
7,985 reviews
Search Delta flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Greenville?

Finding the right flight to Greenville from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Greenville quick and easy, saving you time and money.

Can I find flights from Panama City to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Panama City with this policy.

How can momondo help me find flights from Panama City to Greenville?

momondo helps you find the best flight between Panama City and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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