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Cheap flights from Orlando Airport to Mayagüez from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Airport to Mayagüez departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Orlando Airport to Mayagüez

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:20 pm - 9:42 am
MCO
-
MAZ
10h 22m
1 stop
Multiple Airlines Logo
1:19 pm - 6:02 am
MAZ
-
MCO
16h 43m
1 stop
$465Multiple Airlines
Fri, May 8 - Tue, May 12
Multiple Airlines Logo
5:01 am - 9:42 am
MCO
-
MAZ
4h 41m
1 stop
Multiple Airlines Logo
1:19 pm - 8:05 pm
MAZ
-
MCO
6h 46m
1 stop
$513Multiple Airlines
Wed, Jul 22 - Wed, Jul 29
JetBlue Logo
5:01 am - 9:42 am
MCO
-
MAZ
4h 41m
1 stop
JetBlue Logo
4:13 pm - 11:53 pm
MAZ
-
MCO
7h 40m
1 stop
$528JetBlue
Mon, Jul 27 - Sat, Aug 15
JetBlue Logo
5:01 am - 9:42 am
MCO
-
MAZ
4h 41m
1 stop
JetBlue Logo
4:13 pm - 9:07 pm
MAZ
-
MCO
4h 54m
1 stop
$546JetBlue
Mon, Jul 27 - Sat, Aug 15
JetBlue Logo
5:01 am - 9:42 am
MCO
-
MAZ
4h 41m
1 stop
JetBlue Logo
1:25 pm - 7:05 pm
MAZ
-
MCO
5h 40m
1 stop
$564JetBlue
Mon, Jul 27 - Sat, Aug 15
JetBlue Logo
5:01 am - 9:42 am
MCO
-
MAZ
4h 41m
1 stop
JetBlue Logo
4:36 pm - 12:59 am
MAZ
-
MCO
8h 23m
1 stop
$566JetBlue
Fri, May 8 - Mon, May 11
JetBlue Logo
1:00 pm - 6:50 pm
MCO
-
MAZ
5h 50m
1 stop
JetBlue Logo
1:25 pm - 9:26 pm
MAZ
-
MCO
8h 01m
1 stop
$568JetBlue
Thu, Aug 13 - Sun, Aug 30
JetBlue Logo
8:00 am - 12:44 pm
MCO
-
MAZ
4h 44m
1 stop
JetBlue Logo
4:36 pm - 12:59 am
MAZ
-
MCO
8h 23m
1 stop
$570JetBlue
Sun, May 17 - Mon, May 18
Multiple Airlines Logo
6:15 am - 6:43 pm
MCO
-
MAZ
12h 28m
2 stops
Multiple Airlines Logo
1:19 pm - 6:52 pm
MAZ
-
MCO
5h 33m
1 stop
$583Multiple Airlines
Fri, May 8 - Tue, May 12
JetBlue Logo
5:55 am - 12:44 pm
MCO
-
MAZ
6h 49m
1 stop
JetBlue Logo
1:25 pm - 8:05 pm
MAZ
-
MCO
6h 40m
1 stop
$586JetBlue
Thu, Jul 30 - Sat, Aug 1

JetBlue flights from Orlando Airport to Mayagüez

Our best JetBlue deals on Orlando Airport to Mayagüez flight tickets
JetBlue
Jul 27
MCO5:01 amOrlando
4h 41m
1 stop
MAZ9:42 amMayagüez Eugenio M De Hostos
Aug 15
MAZ4:13 pmMayagüez Eugenio M De Hostos
7h 40m
1 stop
MCO11:53 pmOrlando
$528
JetBlue
Jul 27
MCO5:01 amOrlando
4h 41m
1 stop
MAZ9:42 amMayagüez Eugenio M De Hostos
Aug 15
MAZ4:13 pmMayagüez Eugenio M De Hostos
4h 54m
1 stop
MCO9:07 pmOrlando
$546
JetBlue
Jul 27
MCO5:01 amOrlando
4h 41m
1 stop
MAZ9:42 amMayagüez Eugenio M De Hostos
Aug 15
MAZ1:25 pmMayagüez Eugenio M De Hostos
5h 40m
1 stop
MCO7:05 pmOrlando
$564

United Airlines flights from Orlando Airport to Mayagüez

Our best United Airlines deals on Orlando Airport to Mayagüez flight tickets
United Airlines
Jul 27
MCO9:40 amOrlando
30h 31m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Aug 15
MAZ1:25 pmMayagüez Eugenio M De Hostos
34h 05m
2 stops
MCO11:30 pmOrlando
$1,296
United Airlines
Aug 13
MCO6:00 amOrlando
9h 49m
2 stops
MAZ3:49 pmMayagüez Eugenio M De Hostos
Aug 30
MAZ1:25 pmMayagüez Eugenio M De Hostos
11h 34m
2 stops
MCO12:59 amOrlando
$1,558
United Airlines
Jul 22
MCO7:09 pmOrlando
21h 02m
2 stops
MAZ4:11 pmMayagüez Eugenio M De Hostos
Jul 29
MAZ1:19 pmMayagüez Eugenio M De Hostos
11h 42m
2 stops
MCO1:01 amOrlando
$1,682

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Airport to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Orlando Airport to Mayagüez that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Fri 5/8

11:20 pm-9:42 am

1 stop10h 22m

Mayagüez Eugenio M De Hostos

Tue 5/12

1:19 pm-6:02 am

1 stop16h 43m

$465

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Wed 7/22

5:01 am-9:42 am

1 stop4h 41m

Mayagüez Eugenio M De Hostos

Wed 7/29

1:19 pm-8:05 pm

1 stop6h 46m

$513

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Mon 7/27

5:01 am-9:42 am

1 stop4h 41m

Mayagüez Eugenio M De Hostos

Sat 8/15

4:13 pm-11:53 pm

1 stop7h 40m

$528
Quickest round-trip

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Mon 7/27

5:01 am-9:42 am

1 stop4h 41m

Mayagüez Eugenio M De Hostos

Sat 8/15

4:13 pm-9:07 pm

1 stop4h 54m

$546

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Mon 7/27

5:01 am-9:42 am

1 stop4h 41m

Mayagüez Eugenio M De Hostos

Sat 8/15

1:25 pm-7:05 pm

1 stop5h 40m

$564

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Fri 5/8

5:01 am-9:42 am

1 stop4h 41m

Mayagüez Eugenio M De Hostos

Mon 5/11

4:36 pm-12:59 am

1 stop8h 23m

$566

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Thu 8/13

1:00 pm-6:50 pm

1 stop5h 50m

Mayagüez Eugenio M De Hostos

Sun 8/30

1:25 pm-9:26 pm

1 stop8h 01m

$568

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Sun 5/17

8:00 am-12:44 pm

1 stop4h 44m

Mayagüez Eugenio M De Hostos

Mon 5/18

4:36 pm-12:59 am

1 stop8h 23m

$570

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Fri 5/8

6:15 am-6:43 pm

2 stops12h 28m

Mayagüez Eugenio M De Hostos

Tue 5/12

1:19 pm-6:52 pm

1 stop5h 33m

$583

OrlandoMayagüez

MCO - MAZ

MCOMAZ

Orlando

Thu 7/30

5:55 am-12:44 pm

1 stop6h 49m

Mayagüez Eugenio M De Hostos

Sat 8/1

1:25 pm-8:05 pm

1 stop6h 40m

$586

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Mayagüez from

How to get the cheapest flight ticket from Orlando Airport to Mayagüez

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Orlando to Mayagüez Eugenio M De Hostos?

JetBlue is the most popular carrier operating from Orlando to Mayagüez Eugenio M De Hostos

What airlines fly to Mayagüez?

Frontier, JetBlue and Spirit Airlines are the top three most popular airlines that fly to Mayagüez from Orlando Airport according to our data. Frontier is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Mayagüez. Keep in mind that there are 5 different airlines that fly to Mayagüez on a routine basis, so you have a few additional options to choose from.

When to book flights from Orlando Airport to Mayagüez

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Mayagüez according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Mayagüez (MCO to MAZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Mayagüez

Fastest flight time

4h 41m

Direct flights

None
The fastest flight from Orlando Airport to Mayagüez takes 4h 41m
There are no direct flights from Orlando Airport to Mayagüez. There are no popular flight routes from Orlando Airport to Mayagüez.
Search flight deals

Frequently asked questions about flying from Orlando Airport to Mayagüez

  • How far is Orlando to Mayagüez Eugenio M De Hostos by plane?

    There are 1141.0 mi between Orlando and Mayagüez Eugenio M De Hostos. A reasonable flight in good conditions will take 4h 41m.

  • When did momondo last update prices for flights from Orlando Airport to Mayagüez Eugenio M De Hostos Airport?

    Prices for flights from Orlando Airport to Mayagüez Eugenio M De Hostos Airport were last updated today.

  • How old do you have to be to fly from Orlando Airport to Mayagüez Eugenio M De Hostos Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Airport to Mayagüez Eugenio M De Hostos Airport.

  • What documentation or ID do you need to fly to Mayagüez Eugenio M De Hostos Airport?

    The travel and health documents you'll need for your trip to Mayagüez Eugenio M De Hostos Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mayagüez Eugenio M De Hostos Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Rincon
Cabo Rojo
Boqueron

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Mayagüez?

Finding the right flight to Mayagüez from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mayagüez quick and easy, saving you time and money.

Can I find flights from Orlando to Mayagüez with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Mayagüez from Orlando with this policy.

How can momondo help me find flights from Orlando to Mayagüez?

Once all potential Orlando to Mayagüez flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Orlando to Mayagüez right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Orlando to Mayagüez now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Mayagüez and let you know when they change.

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