What is the cheapest airline that flies from Ohio to South America?

Spirit Airlines, United Airlines, and JetBlue are the most popular carriers operating from Ohio to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Ohio according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 8 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

How long is the flight from Ohio to South America?

Average flight duration from Ohio to South America depends on which airport you fly into and out of. Flying from Cleveland to Copenhagen is 10h 40m on average, while flying from Cincinnati to Copenhagen is 14h 45m on average. Copenhagen is the most popular airport in South America.

When did momondo last update prices for flights from Ohio to South America?

Prices for flights from Ohio to South America are updated daily.

How many operators does momondo search for flights from Ohio to South America?

As of February 2026, there are 8 operators available to choose from for flights from Ohio to South America.

How old do you have to be to fly from Ohio to South America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Ohio to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$110 Cheap Flights from Ohio to South America in 2026

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Find the cheapest flights from Ohio to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 1:22 pm

PIT

MDE

8h 22m

1 stop

2:17 pm - 11:24 pm

MDE

PIT

8h 07m

1 stop

$296Spirit Airlines

Sun, Mar 22 - Thu, Mar 26

5:35 pm - 12:16 am

CLE

MDE

7h 41m

1 stop

1:11 am - 4:30 pm

MDE

CLE

14h 19m

1 stop

$317Spirit Airlines

Wed, May 6 - Tue, May 12

7:43 pm - 12:16 am

CVG

MDE

29h 33m

2 stops

2:06 pm - 9:54 pm

MDE

CVG

30h 48m

1 stop

$339Multiple Airlines

Sat, May 2 - Sat, May 9

8:15 am - 12:16 am

CLE

MDE

17h 01m

1 stop

1:11 am - 3:16 pm

MDE

CLE

13h 05m

1 stop

$342Multiple Airlines

Tue, May 5 - Tue, May 12

7:00 am - 2:10 pm

PIT

MDE

8h 10m

1 stop

1:20 pm - 10:45 pm

MDE

PIT

8h 25m

1 stop

$346JetBlue

Wed, Apr 15 - Wed, Apr 22

7:30 am - 1:55 pm

PIT

MDE

7h 25m

1 stop

1:20 pm - 10:45 pm

MDE

PIT

8h 25m

1 stop

$347JetBlue

Mon, Apr 13 - Fri, Apr 24

6:00 am - 9:10 pm

PIT

MDE

16h 10m

1 stop

9:45 am - 11:44 pm

MDE

PIT

12h 59m

1 stop

$358United Airlines

Fri, May 1 - Sun, May 10

5:08 pm - 9:20 am

PIT

UIO

17h 12m

2 stops

11:45 pm - 9:04 am

UIO

PIT

8h 19m

1 stop

$533LATAM Airlines

Tue, Mar 17 - Wed, Mar 18

11:23 am - 9:20 am

PIT

UIO

22h 57m

2 stops

11:45 pm - 9:04 am

UIO

PIT

8h 19m

1 stop

$539LATAM Airlines

Tue, Mar 17 - Wed, Mar 18

6:00 am - 11:25 pm

PIT

UIO

18h 25m

1 stop

12:35 am - 3:56 pm

UIO

PIT

14h 21m

1 stop

$596United Airlines

Wed, May 20 - Tue, May 26

Delta flights from Ohio to South America

Our best Delta deals on Ohio to South America flight tickets

Delta

Apr 7

PIT7:05 amPittsburgh

14h 15m

2 stops

LIM8:20 pmLima J Chavez Intl

Apr 14

LIM8:55 amLima J Chavez Intl

14h 40m

2 stops

PIT12:35 amPittsburgh

$615

Delta

Apr 3

PIT4:15 pmPittsburgh

13h 28m

2 stops

UIO4:43 amQuito Mariscal Sucr

Apr 19

UIO6:50 pmQuito Mariscal Sucr

17h 11m

2 stops

PIT1:01 pmPittsburgh

$630

Delta

Apr 23

PIT10:20 amPittsburgh

9h 39m

1 stop

UIO6:59 pmQuito Mariscal Sucr

Apr 25

UIO12:59 amQuito Mariscal Sucr

8h 45m

1 stop

PIT10:44 amPittsburgh

$722

Spirit Airlines flights from Ohio to South America

Our best Spirit Airlines deals on Ohio to South America flight tickets

Spirit Airlines

Mar 22

PIT6:00 amPittsburgh

8h 22m

1 stop

MDE1:22 pmMedellín Jose Maria Cordova Intl

Mar 26

MDE2:17 pmMedellín Jose Maria Cordova Intl

8h 07m

1 stop

PIT11:24 pmPittsburgh

$296

Spirit Airlines

May 6

CLE5:35 pmCleveland Hopkins Intl

7h 41m

1 stop

MDE12:16 amMedellín Jose Maria Cordova Intl

May 12

MDE1:11 amMedellín Jose Maria Cordova Intl

14h 19m

1 stop

CLE4:30 pmCleveland Hopkins Intl

$317

Spirit Airlines

Mar 15

PIT6:00 amPittsburgh

19h 21m

1 stop

MDE12:21 amMedellín Jose Maria Cordova Intl

Mar 19

MDE2:17 pmMedellín Jose Maria Cordova Intl

8h 07m

1 stop

PIT11:24 pmPittsburgh

$319

Fly from

Fly to

Route

Depart

Return

Price

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Sun 3/22

6:00 am-1:22 pm

1 stop8h 22m

Medellín Jose Maria Cordova Intl

Thu 3/26

2:17 pm-11:24 pm

1 stop8h 07m

$296

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Wed 5/6

5:35 pm-12:16 am

1 stop7h 41m

Medellín Jose Maria Cordova Intl

Tue 5/12

1:11 am-4:30 pm

1 stop14h 19m

$317

CincinnatiMedellín

CVG - MDE

CVGMDE

Cincinnati Cinci./N. Kentucky

Sat 5/2

7:43 pm-12:16 am

2 stops29h 33m

Medellín Jose Maria Cordova Intl

Sat 5/9

2:06 pm-9:54 pm

1 stop30h 48m

$339

ClevelandMedellín

CLE - MDE

CLEMDE

Cleveland Hopkins Intl

Tue 5/5

8:15 am-12:16 am

1 stop17h 01m

Medellín Jose Maria Cordova Intl

Tue 5/12

1:11 am-3:16 pm

1 stop13h 05m

$342

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Wed 4/15

7:00 am-2:10 pm

1 stop8h 10m

Medellín Jose Maria Cordova Intl

Wed 4/22

1:20 pm-10:45 pm

1 stop8h 25m

$346

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 4/13

7:30 am-1:55 pm

1 stop7h 25m

Medellín Jose Maria Cordova Intl

Fri 4/24

1:20 pm-10:45 pm

1 stop8h 25m

$347

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Fri 5/1

6:00 am-9:10 pm

1 stop16h 10m

Medellín Jose Maria Cordova Intl

Sun 5/10

9:45 am-11:44 pm

1 stop12h 59m

$358

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Tue 3/17

5:08 pm-9:20 am

2 stops17h 12m

Quito Mariscal Sucr

Wed 3/18

11:45 pm-9:04 am

1 stop8h 19m

$533

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Tue 3/17

11:23 am-9:20 am

2 stops22h 57m

Quito Mariscal Sucr

Wed 3/18

11:45 pm-9:04 am

1 stop8h 19m

$539

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Wed 5/20

6:00 am-11:25 pm

1 stop18h 25m

Quito Mariscal Sucr

Tue 5/26

12:35 am-3:56 pm

1 stop14h 21m

$596

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Ohio to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from Ohio to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $644. If you aren’t able to travel during the month of January, then book flights to South America from Ohio during October instead. Flights to South America in October, while not as cheap as those in January, still average around $684.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Ohio when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $787 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Ohio for as low as $673 on momondo.

Can stopping save me money on Ohio to South America flights?

You could potentially save up to 61% on your flight if you consider stops on a Ohio to South America flight.

Cheap Ohio to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to South America

Fastest flight time	6h 29m
Direct flights	None

The fastest flight from Ohio to South America takes 6h 29m

There are no direct flights from Ohio to South America. There are no popular flight routes from Ohio to South America.

Search flight deals

When did momondo last update prices for flights from Ohio to South America?
Prices for flights from Ohio to South America are updated daily.
How many operators does momondo search for flights from Ohio to South America?
As of February 2026, there are 8 operators available to choose from for flights from Ohio to South America.
How old do you have to be to fly from Ohio to South America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Ohio to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Ohio to South America

Compare and see reviews for airlines that fly from Ohio to South America with momondo

Airline	Rating	Free Cancellation	Price
Frontier	PriceFrom $74	Free Cancellation	Rating 5.7 3,045 reviews	Search Frontier flights
Spirit Airlines	PriceFrom $244	Free Cancellation	Rating 6.3 8,482 reviews	Search Spirit Airlines flights
Delta	PriceFrom $413	Free Cancellation	Rating 7.9 8,241 reviews	Search Delta flights
American Airlines	PriceFrom $443	Free Cancellation	Rating 7.2 11,341 reviews	Search American Airlines flights
United Airlines	PriceFrom $462	Free Cancellation	Rating 7.4 9,339 reviews	Search United Airlines flights
LATAM Airlines	PriceFrom $472	Free Cancellation	Rating 7.5 1,919 reviews	Search LATAM Airlines flights
Copa Airlines	PriceFrom $536	Free Cancellation	Rating 7.5 1,555 reviews	Search Copa Airlines flights
Air Canada	PriceFrom $744	Free Cancellation	Rating 7.1 10,738 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Ohio to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Ohio to South America with flexible booking policies on momondo?

Yes. All flights to South America from Ohio on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Ohio to South America?

momondo provides multiple filters to help you find the best flight to South America from Ohio. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Ohio to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Ohio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.