Cheap flights from Ohio to South America from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to South America departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:10 am - 1:12 pm
DTW
-
BOG
8h 02m
1 stop
Spirit Airlines Logo
2:08 pm - 9:03 am
BOG
-
DTW
17h 55m
1 stop
$363Spirit Airlines
Sun, May 3 - Sun, May 10
Multiple Airlines Logo
5:45 am - 1:22 pm
DTW
-
MDE
8h 37m
1 stop
Multiple Airlines Logo
2:06 pm - 11:40 am
MDE
-
DTW
44h 34m
2 stops
$366Multiple Airlines
Tue, Apr 14 - Fri, Apr 24
JetBlue Logo
6:25 am - 2:15 pm
PIT
-
MDE
8h 50m
1 stop
JetBlue Logo
1:25 pm - 10:53 pm
MDE
-
PIT
8h 28m
1 stop
$382JetBlue
Tue, Sep 29 - Wed, Oct 7
JetBlue Logo
6:25 am - 2:15 pm
PIT
-
MDE
8h 50m
1 stop
JetBlue Logo
1:25 pm - 10:53 pm
MDE
-
PIT
8h 28m
1 stop
$387JetBlue
Mon, Sep 28 - Thu, Oct 1
United Airlines Logo
6:00 am - 9:10 pm
PIT
-
MDE
16h 10m
1 stop
United Airlines Logo
9:45 am - 1:05 pm
MDE
-
PIT
26h 20m
2 stops
$392United Airlines
Mon, Apr 20 - Fri, Apr 24
United Airlines Logo
10:35 am - 9:10 pm
PIT
-
MDE
35h 35m
2 stops
United Airlines Logo
9:45 am - 1:09 pm
MDE
-
PIT
26h 24m
2 stops
$406United Airlines
Sat, May 16 - Sat, May 23
LATAM Airlines Logo
5:00 pm - 9:22 am
PIT
-
UIO
17h 22m
2 stops
LATAM Airlines Logo
12:59 am - 6:39 pm
UIO
-
PIT
16h 40m
1 stop
$615LATAM Airlines
Mon, Apr 20 - Wed, Apr 22
LATAM Airlines Logo
5:00 pm - 9:22 am
PIT
-
UIO
17h 22m
2 stops
LATAM Airlines Logo
6:50 pm - 6:39 pm
UIO
-
PIT
22h 49m
2 stops
$619LATAM Airlines
Mon, Apr 20 - Thu, Apr 23
Delta Logo
4:55 pm - 4:43 am
PIT
-
UIO
12h 48m
2 stops
Delta Logo
6:50 pm - 2:54 pm
UIO
-
PIT
19h 04m
2 stops
$642Delta
Mon, Jun 22 - Wed, Jul 1
Delta Logo
6:00 am - 6:59 pm
PIT
-
UIO
13h 59m
1 stop
Delta Logo
12:59 am - 5:10 pm
UIO
-
PIT
15h 11m
1 stop
$647Delta
Thu, Sep 10 - Sat, Sep 19

Spirit Airlines flights from Ohio to South America

Our best Spirit Airlines deals on Ohio to South America flight tickets
Spirit Airlines
Apr 12
DTW5:45 amDetroit Metropolitan Wayne County
8h 26m
1 stop
BOG1:11 pmBogotá El Dorado
Apr 14
BOG2:10 pmBogotá El Dorado
8h 49m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$363
Spirit Airlines
Apr 17
PIT6:35 amPittsburgh
7h 33m
1 stop
MDE1:08 pmMedellín Jose Maria Cordova Intl
Apr 22
MDE1:55 pmMedellín Jose Maria Cordova Intl
8h 26m
1 stop
PIT11:21 pmPittsburgh
$373
Spirit Airlines
Apr 14
DTW5:45 amDetroit Metropolitan Wayne County
8h 37m
1 stop
MDE1:22 pmMedellín Jose Maria Cordova Intl
Apr 24
MDE2:06 pmMedellín Jose Maria Cordova Intl
8h 53m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$380

LATAM Airlines flights from Ohio to South America

Our best LATAM Airlines deals on Ohio to South America flight tickets
LATAM Airlines
Apr 17
PIT11:55 amPittsburgh
21h 20m
2 stops
MDE8:15 amMedellín Jose Maria Cordova Intl
Apr 22
MDE7:55 amMedellín Jose Maria Cordova Intl
15h 40m
2 stops
PIT12:35 amPittsburgh
$428
LATAM Airlines
Apr 22
PIT6:00 amPittsburgh
16h 10m
2 stops
MDE9:10 pmMedellín Jose Maria Cordova Intl
Apr 29
MDE8:25 amMedellín Jose Maria Cordova Intl
23h 50m
2 stops
PIT9:15 amPittsburgh
$430
LATAM Airlines
Apr 15
PIT7:05 amPittsburgh
16h 25m
2 stops
MDE10:30 pmMedellín Jose Maria Cordova Intl
Apr 20
MDE8:25 amMedellín Jose Maria Cordova Intl
23h 50m
2 stops
PIT9:15 amPittsburgh
$431

momondo Fare Finder

 
Customize your flight search to find flights from Ohio to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Ohio to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitBogotá

DTW - BOG

DTWBOG

Detroit Metropolitan Wayne County

Sun 5/3

6:10 am-1:12 pm

1 stop8h 02m

Bogotá El Dorado

Sun 5/10

2:08 pm-9:03 am

1 stop17h 55m

$363

DetroitMedellín

DTW - MDE

DTWMDE

Detroit Metropolitan Wayne County

Tue 4/14

5:45 am-1:22 pm

1 stop8h 37m

Medellín Jose Maria Cordova Intl

Fri 4/24

2:06 pm-11:40 am

2 stops44h 34m

$366
Quickest round-trip

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Tue 9/29

6:25 am-2:15 pm

1 stop8h 50m

Medellín Jose Maria Cordova Intl

Wed 10/7

1:25 pm-10:53 pm

1 stop8h 28m

$382

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 9/28

6:25 am-2:15 pm

1 stop8h 50m

Medellín Jose Maria Cordova Intl

Thu 10/1

1:25 pm-10:53 pm

1 stop8h 28m

$387

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 4/20

6:00 am-9:10 pm

1 stop16h 10m

Medellín Jose Maria Cordova Intl

Fri 4/24

9:45 am-1:05 pm

2 stops26h 20m

$392

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Sat 5/16

10:35 am-9:10 pm

2 stops35h 35m

Medellín Jose Maria Cordova Intl

Sat 5/23

9:45 am-1:09 pm

2 stops26h 24m

$406

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Mon 4/20

5:00 pm-9:22 am

2 stops17h 22m

Quito Mariscal Sucr

Wed 4/22

12:59 am-6:39 pm

1 stop16h 40m

$615

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Mon 4/20

5:00 pm-9:22 am

2 stops17h 22m

Quito Mariscal Sucr

Thu 4/23

6:50 pm-6:39 pm

2 stops22h 49m

$619

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Mon 6/22

4:55 pm-4:43 am

2 stops12h 48m

Quito Mariscal Sucr

Wed 7/1

6:50 pm-2:54 pm

2 stops19h 04m

$642

PittsburghQuito

PIT - UIO

PITUIO

Pittsburgh

Thu 9/10

6:00 am-6:59 pm

1 stop13h 59m

Quito Mariscal Sucr

Sat 9/19

12:59 am-5:10 pm

1 stop15h 11m

$647

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Ohio to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from Ohio to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $644. If you aren’t able to travel during the month of January, then book flights to South America from Ohio during October instead. Flights to South America in October, while not as cheap as those in January, still average around $684.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Ohio when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $787 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Ohio for as low as $695 on momondo.

Can stopping save me money on Ohio to South America flights?

You could potentially save up to 59% on your flight if you consider stops on a Ohio to South America flight.

Cheap Ohio to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to South America

Fastest flight time

6h 31m

Direct flights

None
The fastest flight from Ohio to South America takes 6h 31m
There are no direct flights from Ohio to South America. There are no popular flight routes from Ohio to South America.

Frequently asked questions about flying from Ohio to South America

  • When did momondo last update prices for flights from Ohio to South America?

    Prices for flights from Ohio to South America are updated daily.

  • How many operators does momondo search for flights from Ohio to South America?

  • How old do you have to be to fly from Ohio to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Ohio to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Ohio to South America

Compare and see reviews for airlines that fly from Ohio to South America with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $74Free CancellationRating
5.7
3,000 reviews
Search Frontier flights
Spirit AirlinesPriceFrom $244Free CancellationRating
6.3
8,589 reviews
Search Spirit Airlines flights
DeltaPriceFrom $532Free CancellationRating
7.9
8,387 reviews
Search Delta flights
Copa AirlinesPriceFrom $536Free CancellationRating
7.5
1,577 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $546Free CancellationRating
7.4
1,910 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $551Free CancellationRating
7.1
11,562 reviews
Search American Airlines flights
United AirlinesPriceFrom $553Free CancellationRating
7.4
9,547 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Ohio to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Ohio to South America with flexible booking policies on momondo?

Yes. All flights to South America from Ohio on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Ohio to South America?

momondo provides multiple filters to help you find the best flight to South America from Ohio. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Ohio to South America right now. Can momondo alert me if prices change?

Price alerts on flights to South America from Ohio are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your South America trip

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1 adult
Mon 5/4
Mon 5/11

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