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Cheap flights from Chicago O'Hare Intl Airport to Florence from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Florence departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago O'Hare Intl Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:32 pm - 7:10 pm
ORD
-
MSL
25h 38m2 stops
Multiple Airlines Logo
1:00 pm - 9:56 pm
MSL
-
ORD
8h 56m1 stop
$287Multiple Airlines
mié., ene. 21 - dom., ene. 25
Multiple Airlines Logo
5:32 pm - 7:10 pm
ORD
-
MSL
25h 38m2 stops
Multiple Airlines Logo
7:25 am - 11:46 pm
MSL
-
ORD
16h 21m2 stops
$353Multiple Airlines
mié., ene. 21 - dom., ene. 25
Multiple Airlines Logo
12:42 pm - 7:10 pm
ORD
-
MSL
30h 28m3 stops
Multiple Airlines Logo
7:25 am - 11:46 pm
MSL
-
ORD
16h 21m2 stops
$368Multiple Airlines
mié., ene. 21 - dom., ene. 25
Multiple Airlines Logo
12:42 pm - 7:10 pm
ORD
-
MSL
30h 28m3 stops
Multiple Airlines Logo
7:25 am - 11:47 am
MSL
-
ORD
28h 22m3 stops
$391Multiple Airlines
mié., ene. 21 - dom., ene. 25
Contour Logo
11:20 am - 7:10 pm
ORD
-
MSL
7h 50m2 stops
Contour Logo
1:00 pm - 4:15 pm
MSL
-
ORD
27h 15m2 stops
$410Contour
lun., may. 11 - vie., may. 15
Multiple Airlines Logo
11:20 am - 7:10 pm
ORD
-
MSL
7h 50m2 stops
Multiple Airlines Logo
1:00 pm - 2:41 pm
MSL
-
ORD
25h 41m3 stops
$482Multiple Airlines
lun., may. 11 - vie., may. 15

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Florence, Alabama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 8, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Florence, Alabama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

mié. 1/21

5:32 pm-7:10 pm

2 stops25h 38m

Florence Muscle Shoals

dom. 1/25

1:00 pm-9:56 pm

1 stop8h 56m

$287

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

mié. 1/21

5:32 pm-7:10 pm

2 stops25h 38m

Florence Muscle Shoals

dom. 1/25

7:25 am-11:46 pm

2 stops16h 21m

$353

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

mié. 1/21

12:42 pm-7:10 pm

3 stops30h 28m

Florence Muscle Shoals

dom. 1/25

7:25 am-11:46 pm

2 stops16h 21m

$368

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

mié. 1/21

12:42 pm-7:10 pm

3 stops30h 28m

Florence Muscle Shoals

dom. 1/25

7:25 am-11:47 am

3 stops28h 22m

$391

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

lun. 5/11

11:20 am-7:10 pm

2 stops7h 50m

Florence Muscle Shoals

vie. 5/15

1:00 pm-4:15 pm

2 stops27h 15m

$410

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

lun. 5/11

11:20 am-7:10 pm

2 stops7h 50m

Florence Muscle Shoals

vie. 5/15

1:00 pm-2:41 pm

3 stops25h 41m

$482

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

lun. 2/23

11:46 am-11:50 am

1 stop24h 04m

$113

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

lun. 2/23

8:16 pm-11:50 am

2 stops15h 34m

$154

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

lun. 2/23

12:05 pm-7:10 pm

3 stops31h 05m

$260

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Florence, Alabama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, Alabama?

United Airlines, American Airlines and Denver Air Connection are the top three most popular airlines that fly to Florence, Alabama from Chicago O'Hare Intl Airport according to our data. United Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Florence, Alabama. Keep in mind that there are 3 different airlines that fly to Florence, Alabama on a routine basis, so you have a few additional options to choose from.

When to book flights from Chicago O'Hare Intl Airport to Florence, Alabama

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Florence, Alabama according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Florence, Alabama (ORD to MSL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Florence, Alabama

Fastest flight time

19h 12m

Direct flights

None
The fastest flight from Chicago O'Hare Intl Airport to Florence, Alabama takes 19h 12m
There are no direct flights from Chicago O'Hare Intl Airport to Florence, Alabama. There are no popular flight routes from Chicago O'Hare Intl Airport to Florence, Alabama.
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  • How far is Chicago O'Hare Intl to Florence Muscle Shoals by plane?

    Florence Muscle Shoals is 495.9 mi away from Chicago O'Hare Intl. 19h 12m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport are updated daily.

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport.

  • What documentation or ID do you need to fly to Florence Muscle Shoals Airport?

    The required travel and health documents for your Florence Muscle Shoals Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Muscle Shoals Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Muscle Shoals
Sheffield

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Chicago.

Can I find flights from Chicago to Florence with flexible booking policies on momondo?

Flights from Chicago to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Florence?

Once all potential Chicago to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Chicago to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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sáb. 2/7
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