Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Florence from $343

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Florence departing on 11/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:31 pm - 7:10 pmORD-MSL
28h 39m2 stops
Multiple Airlines Logo
7:25 am - 5:39 pmMSL-ORD
10h 14m1 stop
$343Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:53 am - 7:10 pmORD-MSL
7h 17m1 stop
Multiple Airlines Logo
1:00 pm - 5:39 pmMSL-ORD
28h 39m1 stop
$353Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:02 am - 7:10 pmORD-MSL
32h 08m3 stops
Multiple Airlines Logo
7:25 am - 11:06 pmMSL-ORD
15h 41m2 stops
$362Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:53 am - 7:10 pmORD-MSL
7h 17m1 stop
Multiple Airlines Logo
1:00 pm - 5:39 pmMSL-ORD
28h 39m1 stop
$364Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:53 am - 7:10 pmORD-MSL
7h 17m1 stop
Multiple Airlines Logo
7:25 am - 11:06 pmMSL-ORD
15h 41m2 stops
$371Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:02 am - 7:10 pmORD-MSL
32h 08m3 stops
Multiple Airlines Logo
7:25 am - 11:06 pmMSL-ORD
15h 41m2 stops
$377Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
3:26 pm - 7:10 pmORD-MSL
27h 44m2 stops
Multiple Airlines Logo
7:25 am - 11:06 pmMSL-ORD
15h 41m2 stops
$391Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
3:26 pm - 7:10 pmORD-MSL
27h 44m2 stops
Multiple Airlines Logo
7:25 am - 11:06 pmMSL-ORD
15h 41m2 stops
$402Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:02 am - 7:10 pmORD-MSL
32h 08m3 stops
Multiple Airlines Logo
7:25 am - 12:56 pmMSL-ORD
29h 31m3 stops
$419Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21
Multiple Airlines Logo
11:02 am - 7:10 pmORD-MSL
32h 08m3 stops
Multiple Airlines Logo
7:25 am - 9:17 amMSL-ORD
25h 52m3 stops
$424Multiple Airlines
Find Deal
Mon, Nov 17 - Fri, Nov 21

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Florence, Alabama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Florence, Alabama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

2:31 pm-7:10 pm

2 stops28h 39m

Florence Muscle Shoals

Fri 11/21

7:25 am-5:39 pm

1 stop10h 14m

$343

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:53 am-7:10 pm

1 stop7h 17m

Florence Muscle Shoals

Fri 11/21

1:00 pm-5:39 pm

1 stop28h 39m

$353

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:02 am-7:10 pm

3 stops32h 08m

Florence Muscle Shoals

Fri 11/21

7:25 am-11:06 pm

2 stops15h 41m

$362

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:53 am-7:10 pm

1 stop7h 17m

Florence Muscle Shoals

Fri 11/21

1:00 pm-5:39 pm

1 stop28h 39m

$364

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:53 am-7:10 pm

1 stop7h 17m

Florence Muscle Shoals

Fri 11/21

7:25 am-11:06 pm

2 stops15h 41m

$371

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:02 am-7:10 pm

3 stops32h 08m

Florence Muscle Shoals

Fri 11/21

7:25 am-11:06 pm

2 stops15h 41m

$377

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

3:26 pm-7:10 pm

2 stops27h 44m

Florence Muscle Shoals

Fri 11/21

7:25 am-11:06 pm

2 stops15h 41m

$391

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

3:26 pm-7:10 pm

2 stops27h 44m

Florence Muscle Shoals

Fri 11/21

7:25 am-11:06 pm

2 stops15h 41m

$402

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:02 am-7:10 pm

3 stops32h 08m

Florence Muscle Shoals

Fri 11/21

7:25 am-12:56 pm

3 stops29h 31m

$419

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Mon 11/17

11:02 am-7:10 pm

3 stops32h 08m

Florence Muscle Shoals

Fri 11/21

7:25 am-9:17 am

3 stops25h 52m

$424

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Florence, Alabama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, Alabama?

United Airlines, American Airlines and Denver Air Connection are the top three most popular airlines that fly to Florence, Alabama from Chicago O'Hare Intl Airport according to our data. United Airlines is the first choice among our users, with 57% of people opting to fly with this airline when traveling to Florence, Alabama. Keep in mind that there are 3 different airlines that fly to Florence, Alabama on a routine basis, so you have a few additional options to choose from.

When to book flights from Chicago O'Hare Intl Airport to Florence, Alabama

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Florence, Alabama according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Florence, Alabama (ORD to MSL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Florence, Alabama

Direct flights

None
There are no direct flights from Chicago O'Hare Intl Airport to Florence, Alabama. There are no popular flight routes from Chicago O'Hare Intl Airport to Florence, Alabama.
Search flight deals

  • How far is Chicago O'Hare Intl to Florence Muscle Shoals by plane?

    Florence Muscle Shoals is 495.9 mi away from Chicago O'Hare Intl. 7h 17m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport are updated daily.

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Florence Muscle Shoals Airport.

  • What documentation or ID do you need to fly to Florence Muscle Shoals Airport?

    The required travel and health documents for your Florence Muscle Shoals Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Muscle Shoals Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Muscle Shoals
Sheffield

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Chicago.

Can I find flights from Chicago to Florence with flexible booking policies on momondo?

Flights from Chicago to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Florence?

Once all potential Chicago to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Chicago to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florence, Alabama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 12/3
Wed 12/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States